|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-424 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 862.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 1 MAVIEQVGAREILDSRGNPTVEVEVALDDGTLGRAAVPSGASTGEHEAVELRDKDAKRYGGKGVEQAVAGVLDDIGPELT 80
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 81 GIEAVEQRLVDQKLVDLDGTPDKSRLGANAVLGVSLAVAKAAAESSGLELFRYLGGPNSHVLPVPMMNILNGGAHADNDV 160
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 161 DIQEFMIAPIGADSFREALRWGAEVYHALKAVLKKQGLATGLGDEGGFAPNLKSNREALDLITTAIGNAGYAPGRDIALA 240
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 241 LDVAAAELYADGVYTF--EGSKRSAEQLGSYYAELVGQYPLVSIEDPLGEDDWVGWAHLTSSLGDRVQLVGDDLFVTNLE 318
Cdd:COG0148 241 LDVAASEFYKDGKYHLkgEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTNPK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 319 RLDDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSGETEDTTIADLAVSTGCGQIKSGAPARSDRVAK 398
Cdd:COG0148 321 RLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERVAK 400
|
410 420
....*....|....*....|....*.
gi 521985204 399 YNQLLRIEEELGDAARYAGDLAFPRF 424
Cdd:COG0148 401 YNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-424 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 837.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 1 MAVIEQVGAREILDSRGNPTVEVEVALDDGTLGRAAVPSGASTGEHEAVELRDKDAKRYGGKGVEQAVAGVLDDIGPELT 80
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 81 GIEAVEQRLVDQKLVDLDGTPDKSRLGANAVLGVSLAVAKAAAESSGLELFRYLGGPNSHVLPVPMMNILNGGAHADNDV 160
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 161 DIQEFMIAPIGADSFREALRWGAEVYHALKAVLKKQGLATGLGDEGGFAPNLKSNREALDLITTAIGNAGYAPGRDIALA 240
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 241 LDVAAAELYADGVYTFEGSKRSAEQLGSYYAELVGQYPLVSIEDPLGEDDWVGWAHLTSSLGDRVQLVGDDLFVTNLERL 320
Cdd:PRK00077 241 LDCAASEFYKDGKYVLEGEGLTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTNTKRL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 321 DDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSGETEDTTIADLAVSTGCGQIKSGAPARSDRVAKYN 400
Cdd:PRK00077 321 KKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKYN 400
|
410 420
....*....|....*....|....
gi 521985204 401 QLLRIEEELGDAARYAGDLAFPRF 424
Cdd:PRK00077 401 QLLRIEEELGDAARYAGKKAFKNL 424
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
7-408 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 728.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 7 VGAREILDSRGNPTVEVEVALDDGTLGRAAVPSGASTGEHEAVELRDKDAKRYGGKGVEQAVAGVLDDIGPELTGIEAVE 86
Cdd:cd03313 2 IKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVTD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 87 QRLVDQKLVDLDGTPDKSRLGANAVLGVSLAVAKAAAESSGLELFRYLGGPNSHVLPVPMMNILNGGAHADNDVDIQEFM 166
Cdd:cd03313 82 QRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEFM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 167 IAPIGADSFREALRWGAEVYHALKAVLKKQG--LATGLGDEGGFAPNLKSNREALDLITTAIGNAGYAPGRDIALALDVA 244
Cdd:cd03313 162 IVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDVA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 245 AAELYADGVYTF---EGSKRSAEQLGSYYAELVGQYPLVSIEDPLGEDDWVGWAHLTSSLGDRVQLVGDDLFVTNLERLD 321
Cdd:cd03313 242 ASEFYDEGKYVYdsdEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPERLK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 322 DGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSGETEDTTIADLAVSTGCGQIKSGAPARSDRVAKYNQ 401
Cdd:cd03313 322 KGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKYNQ 401
|
....*..
gi 521985204 402 LLRIEEE 408
Cdd:cd03313 402 LLRIEEE 408
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-424 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 725.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 4 IEQVGAREILDSRGNPTVEVEVALDDGTLGRAAVPSGASTGEHEAVELRDKDAKRYGGKGVEQAVAGVLDDIGPELTGIE 83
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 84 AVEQRLVDQKLVDLDGTPDKSRLGANAVLGVSLAVAKAAAESSGLELFRYLGGPNSHVLPVPMMNILNGGAHADNDVDIQ 163
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 164 EFMIAPIGADSFREALRWGAEVYHALKAVLKKQGLATGLGDEGGFAPNLKSNREALDLITTAIGNAGYAPGRDIALALDV 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 244 AAAELY--ADGVYTFEGSKR--SAEQLGSYYAELVGQYPLVSIEDPLGEDDWVGWAHLTSSLGDRVQLVGDDLFVTNLER 319
Cdd:TIGR01060 241 AASEFYdeEDGKYVYKGENKqlTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 320 LDDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSGETEDTTIADLAVSTGCGQIKSGAPARSDRVAKY 399
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400
|
410 420
....*....|....*....|....*
gi 521985204 400 NQLLRIEEELGDAARYAGDLAFPRF 424
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
139-417 |
2.69e-152 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 433.06 E-value: 2.69e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 139 SHVLPVPMMNILNGGAHADNDVDIQEFMIAPIGADSFREALRWGAEVYHALKAVLKKQG--LATGLGDEGGFAPNLKSNR 216
Cdd:pfam00113 1 SYVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 217 EALDLITTAIGNAGYAPgrDIALALDVAAAELYA--DGVY--TFEGSKR------SAEQLGSYYAELVGQYPLVSIEDPL 286
Cdd:pfam00113 81 EALDLIVEAIEKAGYKG--KIKIAMDVASSEFYNkkDGKYdlDFKGEKSdkskklTSAQLADLYEELVKKYPIVSIEDPF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 287 GEDDWVGWAHLTSSLGDRVQLVGDDLFVTNLERLDDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSG 366
Cdd:pfam00113 159 DEDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSG 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 521985204 367 ETEDTTIADLAVSTGCGQIKSGAPARSDRVAKYNQLLRIEEELGDAARYAG 417
Cdd:pfam00113 239 ETEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAG 289
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-424 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 862.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 1 MAVIEQVGAREILDSRGNPTVEVEVALDDGTLGRAAVPSGASTGEHEAVELRDKDAKRYGGKGVEQAVAGVLDDIGPELT 80
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 81 GIEAVEQRLVDQKLVDLDGTPDKSRLGANAVLGVSLAVAKAAAESSGLELFRYLGGPNSHVLPVPMMNILNGGAHADNDV 160
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 161 DIQEFMIAPIGADSFREALRWGAEVYHALKAVLKKQGLATGLGDEGGFAPNLKSNREALDLITTAIGNAGYAPGRDIALA 240
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 241 LDVAAAELYADGVYTF--EGSKRSAEQLGSYYAELVGQYPLVSIEDPLGEDDWVGWAHLTSSLGDRVQLVGDDLFVTNLE 318
Cdd:COG0148 241 LDVAASEFYKDGKYHLkgEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTNPK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 319 RLDDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSGETEDTTIADLAVSTGCGQIKSGAPARSDRVAK 398
Cdd:COG0148 321 RLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERVAK 400
|
410 420
....*....|....*....|....*.
gi 521985204 399 YNQLLRIEEELGDAARYAGDLAFPRF 424
Cdd:COG0148 401 YNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-424 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 837.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 1 MAVIEQVGAREILDSRGNPTVEVEVALDDGTLGRAAVPSGASTGEHEAVELRDKDAKRYGGKGVEQAVAGVLDDIGPELT 80
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 81 GIEAVEQRLVDQKLVDLDGTPDKSRLGANAVLGVSLAVAKAAAESSGLELFRYLGGPNSHVLPVPMMNILNGGAHADNDV 160
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 161 DIQEFMIAPIGADSFREALRWGAEVYHALKAVLKKQGLATGLGDEGGFAPNLKSNREALDLITTAIGNAGYAPGRDIALA 240
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 241 LDVAAAELYADGVYTFEGSKRSAEQLGSYYAELVGQYPLVSIEDPLGEDDWVGWAHLTSSLGDRVQLVGDDLFVTNLERL 320
Cdd:PRK00077 241 LDCAASEFYKDGKYVLEGEGLTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTNTKRL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 321 DDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSGETEDTTIADLAVSTGCGQIKSGAPARSDRVAKYN 400
Cdd:PRK00077 321 KKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKYN 400
|
410 420
....*....|....*....|....
gi 521985204 401 QLLRIEEELGDAARYAGDLAFPRF 424
Cdd:PRK00077 401 QLLRIEEELGDAARYAGKKAFKNL 424
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
7-408 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 728.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 7 VGAREILDSRGNPTVEVEVALDDGTLGRAAVPSGASTGEHEAVELRDKDAKRYGGKGVEQAVAGVLDDIGPELTGIEAVE 86
Cdd:cd03313 2 IKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVTD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 87 QRLVDQKLVDLDGTPDKSRLGANAVLGVSLAVAKAAAESSGLELFRYLGGPNSHVLPVPMMNILNGGAHADNDVDIQEFM 166
Cdd:cd03313 82 QRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEFM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 167 IAPIGADSFREALRWGAEVYHALKAVLKKQG--LATGLGDEGGFAPNLKSNREALDLITTAIGNAGYAPGRDIALALDVA 244
Cdd:cd03313 162 IVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDVA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 245 AAELYADGVYTF---EGSKRSAEQLGSYYAELVGQYPLVSIEDPLGEDDWVGWAHLTSSLGDRVQLVGDDLFVTNLERLD 321
Cdd:cd03313 242 ASEFYDEGKYVYdsdEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPERLK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 322 DGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSGETEDTTIADLAVSTGCGQIKSGAPARSDRVAKYNQ 401
Cdd:cd03313 322 KGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKYNQ 401
|
....*..
gi 521985204 402 LLRIEEE 408
Cdd:cd03313 402 LLRIEEE 408
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-424 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 725.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 4 IEQVGAREILDSRGNPTVEVEVALDDGTLGRAAVPSGASTGEHEAVELRDKDAKRYGGKGVEQAVAGVLDDIGPELTGIE 83
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 84 AVEQRLVDQKLVDLDGTPDKSRLGANAVLGVSLAVAKAAAESSGLELFRYLGGPNSHVLPVPMMNILNGGAHADNDVDIQ 163
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 164 EFMIAPIGADSFREALRWGAEVYHALKAVLKKQGLATGLGDEGGFAPNLKSNREALDLITTAIGNAGYAPGRDIALALDV 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 244 AAAELY--ADGVYTFEGSKR--SAEQLGSYYAELVGQYPLVSIEDPLGEDDWVGWAHLTSSLGDRVQLVGDDLFVTNLER 319
Cdd:TIGR01060 241 AASEFYdeEDGKYVYKGENKqlTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 320 LDDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSGETEDTTIADLAVSTGCGQIKSGAPARSDRVAKY 399
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400
|
410 420
....*....|....*....|....*
gi 521985204 400 NQLLRIEEELGDAARYAGDLAFPRF 424
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| PTZ00081 |
PTZ00081 |
enolase; Provisional |
1-417 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 240259 [Multi-domain] Cd Length: 439 Bit Score: 580.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 1 MAVIEQVGAREILDSRGNPTVEVEVALDDGTLgRAAVPSGASTGEHEAVELRDKDAKRYGGKGVEQAVAGVLDDIGPELT 80
Cdd:PTZ00081 1 MSTIKSIKAREILDSRGNPTVEVDLTTEKGVF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 81 GIEAVEQRLVDQKLVD-LDGTPD-----KSRLGANAVLGVSLAVAKAAAESSGLELFRYL----GGPNSH-VLPVPMMNI 149
Cdd:PTZ00081 80 GKDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLaqlaGKPTDKfVLPVPCFNV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 150 LNGGAHADNDVDIQEFMIAPIGADSFREALRWGAEVYHALKAVLKKQ-GL-ATGLGDEGGFAPNLKSNREALDLITTAIG 227
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKKyGLdATNVGDEGGFAPNIKDPEEALDLLVEAIK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 228 NAGYApGRdIALALDVAAAELYAD--GVY--TF------EGSKRSAEQLGSYYAELVGQYPLVSIEDPLGEDDWVGWAHL 297
Cdd:PTZ00081 240 KAGYE-GK-VKICMDVAASEFYDKekKVYdlDFknpnndKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAKL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 298 TSSLGDRVQLVGDDLFVTNLERLDDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSGETEDTTIADLA 377
Cdd:PTZ00081 318 TAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADLV 397
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 521985204 378 VSTGCGQIKSGAPARSDRVAKYNQLLRIEEELGDAARYAG 417
Cdd:PTZ00081 398 VGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAG 437
|
|
| PLN00191 |
PLN00191 |
enolase |
1-417 |
0e+00 |
|
enolase
Pssm-ID: 215095 [Multi-domain] Cd Length: 457 Bit Score: 548.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 1 MAVIEQVGAREILDSRGNPTVEVEVALDDGTLgRAAVPSGASTGEHEAVELRDKDaKRYGGKGVEQAVAGVLDDIGPELT 80
Cdd:PLN00191 25 MATITKVKARQIIDSRGNPTVEVDLHTSKGMF-RAAVPSGASTGIYEALELRDGD-KDYLGKGVLKAVKNVNEIIAPALI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 81 GIEAVEQRLVDQKLVDLDGTPDKSRLGANAVLGVSLAVAKAAAESSGLELFRY---LGGPNSHVLPVPMMNILNGGAHAD 157
Cdd:PLN00191 103 GMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHiadLAGNKKLVLPVPAFNVINGGSHAG 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 158 NDVDIQEFMIAPIGADSFREALRWGAEVYHALKAVLKKQ--GLATGLGDEGGFAPNLKSNREALDLITTAIGNAGYApGR 235
Cdd:PLN00191 183 NKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT-GK 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 236 dIALALDVAAAELY-ADGVYTFE--------GSKRSAEQLGSYYAELVGQYPLVSIEDPLGEDDWVGWAHLTSSlgDRVQ 306
Cdd:PLN00191 262 -IKIGMDVAASEFYtKDKKYDLDfkeenndgSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSL--EDVQ 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 307 LVGDDLFVTNLERLDDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSGETEDTTIADLAVSTGCGQIK 386
Cdd:PLN00191 339 IVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQIK 418
|
410 420 430
....*....|....*....|....*....|.
gi 521985204 387 SGAPARSDRVAKYNQLLRIEEELGDAARYAG 417
Cdd:PLN00191 419 TGAPCRSERLAKYNQLLRIEEELGDEAVYAG 449
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
139-417 |
2.69e-152 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 433.06 E-value: 2.69e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 139 SHVLPVPMMNILNGGAHADNDVDIQEFMIAPIGADSFREALRWGAEVYHALKAVLKKQG--LATGLGDEGGFAPNLKSNR 216
Cdd:pfam00113 1 SYVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 217 EALDLITTAIGNAGYAPgrDIALALDVAAAELYA--DGVY--TFEGSKR------SAEQLGSYYAELVGQYPLVSIEDPL 286
Cdd:pfam00113 81 EALDLIVEAIEKAGYKG--KIKIAMDVASSEFYNkkDGKYdlDFKGEKSdkskklTSAQLADLYEELVKKYPIVSIEDPF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 287 GEDDWVGWAHLTSSLGDRVQLVGDDLFVTNLERLDDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSG 366
Cdd:pfam00113 159 DEDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSG 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 521985204 367 ETEDTTIADLAVSTGCGQIKSGAPARSDRVAKYNQLLRIEEELGDAARYAG 417
Cdd:pfam00113 239 ETEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAG 289
|
|
| Enolase_N |
pfam03952 |
Enolase, N-terminal domain; |
4-134 |
8.12e-79 |
|
Enolase, N-terminal domain;
Pssm-ID: 461105 [Multi-domain] Cd Length: 131 Bit Score: 239.58 E-value: 8.12e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 4 IEQVGAREILDSRGNPTVEVEVALDDGTLGRAAVPSGASTGEHEAVELRDKDAKRYGGKGVEQAVAGVLDDIGPELTGIE 83
Cdd:pfam03952 1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 521985204 84 AVEQRLVDQKLVDLDGTPDKSRLGANAVLGVSLAVAKAAAESSGLELFRYL 134
Cdd:pfam03952 81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
|
|
| PRK08350 |
PRK08350 |
hypothetical protein; Provisional |
1-414 |
3.02e-25 |
|
hypothetical protein; Provisional
Pssm-ID: 169397 [Multi-domain] Cd Length: 341 Bit Score: 105.66 E-value: 3.02e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 1 MAVIEQVGAREILDSRGNPTVEVEVALDDGtLGRAAVPSgastgeHEAVELRDKDAKRyggkgveqAVAGVLDDIGPELT 80
Cdd:PRK08350 1 MTVIENIIGRVAVLRGGKYSVEVDVITDSG-FGRFAAPI------DENPSLYIAEAHR--------AVSEVDEIIGPELI 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 81 GIEAVEQRLVDQKLVDLDGTPDKSRLGANAVLGVSLAVAKAAAESSGLELFRYLGGPNSHVLPVPMMNILNgGAHADNDV 160
Cdd:PRK08350 66 GFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIGGTFTTELPVPILEFAE-DENFEYYV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 161 DIQEFMiapigadsfrealrwgaEVYHALKAVLKKQGLATGLGDEGgfapnlksnrealdlITTAIGNAGYAPGRDIALA 240
Cdd:PRK08350 145 LVRDLM-----------------EITDVVDAVNKILENSKEVSLEG---------------LSKASEKAGDELGLEVALG 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 241 LdVAAAELYADGVYtfegskrsaeqlgsyyaELVGQYPLVSIEdPLGED----DWVGWAHltsslgdRVQLVGDDLFVTN 316
Cdd:PRK08350 193 I-AQKREMETEKVL-----------------NLVEDNNIAYIK-PIGDEelflELIAGTH-------GVFIDGEYLFRTR 246
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 317 lerldDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSGETEDTTIADLAVSTGCgqiksgaPA---RS 393
Cdd:PRK08350 247 -----NILDRRYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLRC-------PAmliHK 314
|
410 420
....*....|....*....|.
gi 521985204 394 DRVAKYNQLLRIEEELGDAAR 414
Cdd:PRK08350 315 DSVEKINELNRIAEDLGERGR 335
|
|
| enolase_like |
cd00308 |
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ... |
234-381 |
7.77e-10 |
|
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.
Pssm-ID: 238188 [Multi-domain] Cd Length: 229 Bit Score: 58.88 E-value: 7.77e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 234 GRDIALALDVAAAElyadgvytfegSKRSAEQLGSYYAElvgqYPLVSIEDPLGEDDWVGWAHLTSSLGdrVQLVGDDLF 313
Cdd:cd00308 92 GPDARLAVDANGAW-----------TPKEAIRLIRALEK----YGLAWIEEPCAPDDLEGYAALRRRTG--IPIAADESV 154
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 521985204 314 VTNLERLdDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMMSHRSG-ETEDTTIADLAVSTG 381
Cdd:cd00308 155 TTVDDAL-EALELGAVDILQIKPTRVGGLTESRRAADLAEAFGIRVMVHGTLEsSIGTAAALHLAAALP 222
|
|
| NAAAR |
cd03317 |
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of ... |
189-356 |
1.15e-05 |
|
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building blocks for antibiotics, herbicides, and drugs. NAAAR is a member of the enolase superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239433 [Multi-domain] Cd Length: 354 Bit Score: 47.23 E-value: 1.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 189 LKAVLKKQGLATGLGDEGGFAP------NLKSNREALDLITTAIgNAGY-------APGRDIALaldVAA-------AEL 248
Cdd:cd03317 106 LYAKAQGQSLAQYLGGTRDSIPvgvsigIQDDVEQLLKQIERYL-EEGYkriklkiKPGWDVEP---LKAvrerfpdIPL 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 249 YAD--GVYTFEgskrSAEQLgsyyAELvGQYPLVSIEDPLGEDDWVGWAHLTSSLGDRVQLvgdDLFVTNLERLDDGIGR 326
Cdd:cd03317 182 MADanSAYTLA----DIPLL----KRL-DEYGLLMIEQPLAADDLIDHAELQKLLKTPICL---DESIQSAEDARKAIEL 249
|
170 180 190
....*....|....*....|....*....|
gi 521985204 327 GVANALLVKVNQIGTLSETLDAVTLAQTSG 356
Cdd:cd03317 250 GACKIINIKPGRVGGLTEALKIHDLCQEHG 279
|
|
| PTZ00378 |
PTZ00378 |
hypothetical protein; Provisional |
77-409 |
1.26e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 173571 [Multi-domain] Cd Length: 518 Bit Score: 47.18 E-value: 1.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 77 PELTGIEAVEQRLVDQKLVDLDGTPDKSRLGANAVLGVSLAVAKAAAESSGLELFRYL-------GGPNSHVLPVPMMNI 149
Cdd:PTZ00378 117 PRLLQLGARDQREFDSTLRAALSTSPLANVGSAVQWALSIVASLAAARCRSVPLFQYLralfgslTSVETFSMPQLCITF 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 150 LNGGAHADNDVDIQEFMIAPI---GADSfREALRwgaEVYHALKAVLKKQGLATGLGdeGGFAPNLKSN-REALDLITTA 225
Cdd:PTZ00378 197 FGPGNPSTARLALKSVLFSPVmpsGTVL-RERMQ---KIFAAFHHFCQSHNSSVRSD--GSLHWDGFANlTDAVKLATEA 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 226 IGNAGYAPGRDIALALDVAAAELYADGVYTFEGSKR--------------------SAEQLGSYYAELVGQYP--LVSIE 283
Cdd:PTZ00378 271 LRAVQLTPGTDVCLGLRMAASTTRVPATAVADGGAWkeakddcevlyslfpgepdvTGDQLSEYVREQLQAVPdiVVYVE 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 284 DPLGEDDWVGWAHLTSSLGDRVQLVGDDLFV-TNLERLDDGIGRGVANALLVKVNQIGTLSETLDAVTLA-QTSGYKCMM 361
Cdd:PTZ00378 351 DTHCDEDTFGLQRLQAALGDSIVLSGVDVYArSEYKKVESGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVgEDEGRAVTV 430
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 521985204 362 SHRSGETEDTTIADLAVSTGCGQIKSGAPARSDRVAKYNQLLRIEEEL 409
Cdd:PTZ00378 431 LVQTLAGNAATAAHLAVAMGARFLCSGGLFSAHQCEVVSQLASRQDEL 478
|
|
| RspA |
COG4948 |
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane ... |
230-361 |
1.88e-04 |
|
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 443975 [Multi-domain] Cd Length: 359 Bit Score: 43.27 E-value: 1.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 230 GYAPGRDIALALDVAAA-----ELYAD--GVYTFEGSKRSAEQLGsyyaelvgQYPLVSIEDPLGEDDWVGWAHLTSSLg 302
Cdd:COG4948 162 GPDPEEDVERVRAVREAvgpdaRLRVDanGAWTLEEAIRLLRALE--------DLGLEWIEQPLPAEDLEGLAELRRAT- 232
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 521985204 303 dRVQLVGDDLfVTNLERLDDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKCMM 361
Cdd:COG4948 233 -PVPIAADES-LTSRADFRRLIEAGAVDIVNIKLSKVGGLTEALRIAALAEAHGVPVMP 289
|
|
| mandelate_racemase |
cd03321 |
Mandelate racemase (MR) catalyzes the Mg2+-dependent 1,1-proton transfer reaction that ... |
66-363 |
1.59e-03 |
|
Mandelate racemase (MR) catalyzes the Mg2+-dependent 1,1-proton transfer reaction that interconverts the enantiomers of mandelic acid. MR is the first enzyme in the bacterial pathway that converts mandelic acid to benzoic acid and allows this pathway to utilize either enantiomer of mandelate. MR belongs to the enolase superfamily of enzymes, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239437 [Multi-domain] Cd Length: 355 Bit Score: 40.54 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 66 QAVAGVLDDIGPELTGIEAVEqRLVDQKLVD---LDGTPDKSRLganAVLGVSLAVAKAAAESSGLELFRYLGGPNShvl 142
Cdd:cd03321 57 KSLKQLLDDMAALLVGEPLAP-AELERALAKrfrLLGYTGLVRM---AAAGIDMAAWDALAKVHGLPLAKLLGGNPR--- 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 143 PVPmmnilnggAHADNDVDIQEFMIApigadsfrEALRWGAEVYHALKAVLKKqglatglgdeggfaPNLKSNREALDLI 222
Cdd:cd03321 130 PVQ--------AYDSHGLDGAKLATE--------RAVTAAEEGFHAVKTKIGY--------------PTADEDLAVVRSI 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521985204 223 TTAIGnAGYAPGRDIALALDVAAAelyadgvytfegSKRSaeqlgsyyaELVGQYPLVSIEDPLGEDDWVGWAHLTSSLG 302
Cdd:cd03321 180 RQAVG-DGVGLMVDYNQSLTVPEA------------IERG---------QALDQEGLTWIEEPTLQHDYEGHARIASALR 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 521985204 303 DRVQlVGDDLFvtNLERLDDGIGRGVANALLVKVNQIGTLSETLDAVTLAQTSGYKcMMSH 363
Cdd:cd03321 238 TPVQ-MGENWL--GPEEMFKALSAGACDLVMPDLMKIGGVTGWLRASALAEQAGIP-MSSH 294
|
|
| |
