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Concise Results
Standard Results
Full Results
MULTISPECIES: phosphopyruvate hydratase [Spirosoma]
Protein Classification
phosphopyruvate hydratase ( domain architecture ID 11414960 )
phosphopyruvate hydratase (enolase) catalyzes the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways
List of domain hits
Name
Accession
Description
Interval
E-value
Eno
COG0148 Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
1-425
0e+00
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain]
Cd Length: 426
Bit Score: 881.66
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 1 MS T I QSI HAR Q ILDSRGNPTVEV D V RT E N G FL GRAAVPSGASTG T HEAVELRD D DK KV Y M GKGVLKAV S NVNE L I F P E L V 80
Cdd:COG0148 1 MS R I EDV HAR E ILDSRGNPTVEV E V TL E D G AV GRAAVPSGASTG S HEAVELRD G DK SR Y L GKGVLKAV E NVNE E I A P A L I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 81 G ISIFE Q SM IDR I M L ELDGTPNK G RLGANAILGVSLA A AKAAA QEA GLPLYRY I GGVNA N TLPVPMMNI L NGG S HADN SI 160
Cdd:COG0148 81 G MDATD Q RA IDR A M I ELDGTPNK S RLGANAILGVSLA V AKAAA AAL GLPLYRY L GGVNA K TLPVPMMNI I NGG A HADN NV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 161 D F QEFM V MP AN APSFSEALRMG T E I FH T LK G VLK KM GL A T N VGDEGGFAPN I KSNEEA IQT I IQ AIEKAGY R PGED VWI A 240
Cdd:COG0148 161 D I QEFM I MP VG APSFSEALRMG A E V FH A LK K VLK EK GL S T A VGDEGGFAPN L KSNEEA LEL I LE AIEKAGY K PGED IAL A 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 241 M D A A S SEFY D ae A G V YH F k K ST G DK LTS S EM AGFWK D W V N KYPI L SIEDG M AEDDWDGWK AQ T DL L K D n K T QLVGDDLFV 320
Cdd:COG0148 241 L D V A A SEFY K -- D G K YH L - K GE G KE LTS E EM IDYYA D L V D KYPI V SIEDG L AEDDWDGWK LL T EK L G D - K V QLVGDDLFV 316
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 321 TN VT RL QE GI DK G I AN A IL V KVNQIG S LTET I D TVN LAKR NS Y KNIM SHRSGETED A TIADLAVA L N T GQIKTGS A SRS D 400
Cdd:COG0148 317 TN PK RL KK GI EE G A AN S IL I KVNQIG T LTET L D AIE LAKR AG Y TAVI SHRSGETED T TIADLAVA T N A GQIKTGS P SRS E 396
410 420
....*....|....*....|....*
gi 522085333 401 R M AKYNQLLRIEEELG ET A YFP G LK 425
Cdd:COG0148 397 R V AKYNQLLRIEEELG DA A RYA G RS 421
Name
Accession
Description
Interval
E-value
Eno
COG0148 Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
1-425
0e+00
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain]
Cd Length: 426
Bit Score: 881.66
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 1 MS T I QSI HAR Q ILDSRGNPTVEV D V RT E N G FL GRAAVPSGASTG T HEAVELRD D DK KV Y M GKGVLKAV S NVNE L I F P E L V 80
Cdd:COG0148 1 MS R I EDV HAR E ILDSRGNPTVEV E V TL E D G AV GRAAVPSGASTG S HEAVELRD G DK SR Y L GKGVLKAV E NVNE E I A P A L I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 81 G ISIFE Q SM IDR I M L ELDGTPNK G RLGANAILGVSLA A AKAAA QEA GLPLYRY I GGVNA N TLPVPMMNI L NGG S HADN SI 160
Cdd:COG0148 81 G MDATD Q RA IDR A M I ELDGTPNK S RLGANAILGVSLA V AKAAA AAL GLPLYRY L GGVNA K TLPVPMMNI I NGG A HADN NV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 161 D F QEFM V MP AN APSFSEALRMG T E I FH T LK G VLK KM GL A T N VGDEGGFAPN I KSNEEA IQT I IQ AIEKAGY R PGED VWI A 240
Cdd:COG0148 161 D I QEFM I MP VG APSFSEALRMG A E V FH A LK K VLK EK GL S T A VGDEGGFAPN L KSNEEA LEL I LE AIEKAGY K PGED IAL A 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 241 M D A A S SEFY D ae A G V YH F k K ST G DK LTS S EM AGFWK D W V N KYPI L SIEDG M AEDDWDGWK AQ T DL L K D n K T QLVGDDLFV 320
Cdd:COG0148 241 L D V A A SEFY K -- D G K YH L - K GE G KE LTS E EM IDYYA D L V D KYPI V SIEDG L AEDDWDGWK LL T EK L G D - K V QLVGDDLFV 316
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 321 TN VT RL QE GI DK G I AN A IL V KVNQIG S LTET I D TVN LAKR NS Y KNIM SHRSGETED A TIADLAVA L N T GQIKTGS A SRS D 400
Cdd:COG0148 317 TN PK RL KK GI EE G A AN S IL I KVNQIG T LTET L D AIE LAKR AG Y TAVI SHRSGETED T TIADLAVA T N A GQIKTGS P SRS E 396
410 420
....*....|....*....|....*
gi 522085333 401 R M AKYNQLLRIEEELG ET A YFP G LK 425
Cdd:COG0148 397 R V AKYNQLLRIEEELG DA A RYA G RS 421
eno
PRK00077 enolase; Provisional
1-426
0e+00
enolase; Provisional
Pssm-ID: 234617 [Multi-domain]
Cd Length: 425
Bit Score: 843.60
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 1 MS T I QS I H AR Q ILDSRGNPTVEV D V RT E N G FL GRAAVPSGASTG TH EAVELRD D DK KV Y M GKGVLKAV S NVNE L I F P E L V 80
Cdd:PRK00077 1 MS K I ED I I AR E ILDSRGNPTVEV E V TL E D G AF GRAAVPSGASTG ER EAVELRD G DK SR Y L GKGVLKAV E NVNE E I A P A L I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 81 G ISIFE Q SM ID RI M L ELDGTPNK GR LGANAILGVSLA A AKAAA QEA GLPLYRY I GG V NA NT LPVPMMNI L NGG S HADN SI 160
Cdd:PRK00077 81 G LDALD Q RA ID KA M I ELDGTPNK SK LGANAILGVSLA V AKAAA DSL GLPLYRY L GG P NA KV LPVPMMNI I NGG A HADN NV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 161 D F QEFM V MP AN APSF S EALRMG T E I FHTLK G VLK KM GL A T N VGDEGGFAPN I KSNEEA IQT I IQ AIEKAGY R PGED VWI A 240
Cdd:PRK00077 161 D I QEFM I MP VG APSF K EALRMG A E V FHTLK K VLK EK GL S T A VGDEGGFAPN L KSNEEA LDL I LE AIEKAGY K PGED IAL A 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 241 M D A A S SEFY da EA G V Y HFK kst G DK LTS S EM AGFWKDW V N KYPI L SIEDG MA E D DW D GWK AQ T DL L K D n K T QLVGDDLFV 320
Cdd:PRK00077 241 L D C A A SEFY -- KD G K Y VLE --- G EG LTS E EM IDYLAEL V D KYPI V SIEDG LD E N DW E GWK LL T EK L G D - K V QLVGDDLFV 314
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 321 TN VT RL QE GI D KG I AN A IL V KVNQIG S LTET I D TVN LAKR NS Y KNIM SHRSGETED A TIADLAVA L N T GQIKTGS A SRS D 400
Cdd:PRK00077 315 TN TK RL KK GI E KG A AN S IL I KVNQIG T LTET L D AIE LAKR AG Y TAVV SHRSGETED T TIADLAVA T N A GQIKTGS L SRS E 394
410 420
....*....|....*....|....*.
gi 522085333 401 R M AKYNQLLRIEEELG ET A YFP G L K F 426
Cdd:PRK00077 395 R I AKYNQLLRIEEELG DA A RYA G K K A 420
enolase
cd03313 Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
6-414
0e+00
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain]
Cd Length: 408
Bit Score: 748.54
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 6 S I H AR Q ILDSRGNPTVEV D V R TE N G FL GRAAVPSGASTG T HEAVELRD D DK KV Y M GKGVLKAV S NVNE L I F P E L V G ISIF 85
Cdd:cd03313 1 K I K AR E ILDSRGNPTVEV E V T TE D G GV GRAAVPSGASTG E HEAVELRD G DK SR Y L GKGVLKAV K NVNE I I A P A L I G MDVT 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 86 E Q SM ID RIML ELDGTPNK GR LGANAILGVSLA A AKAAA QEA GLPLYRY I GG VN A NT LPVPM M N IL NGG S HA D N SI DFQEF 165
Cdd:cd03313 81 D Q RA ID KLLI ELDGTPNK SK LGANAILGVSLA V AKAAA AAL GLPLYRY L GG LA A YV LPVPM F N VI NGG A HA G N KL DFQEF 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 166 M VM P AN APSFSEALRMG T E IF HTLK G VLKK M G -- LATNVGDEGGFAPN IK SNEEA IQTIIQ AIEKAGY R PG EDVW IA M D A 243
Cdd:cd03313 161 M IV P VG APSFSEALRMG A E VY HTLK K VLKK K G gl LATNVGDEGGFAPN LS SNEEA LDLLVE AIEKAGY E PG KKIA IA L D V 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 244 A S SEFYD ae A G V Y HFKKST G D KLTS S E MAGFW K DW V N KYPI L SIED GMA EDDW D GW KAQ T DL L K D n K T Q L VGDDLFVTN V 323
Cdd:cd03313 241 A A SEFYD -- E G K Y VYDSDE G K KLTS E E LIDYY K EL V K KYPI V SIED PFD EDDW E GW AKL T AK L G D - K I Q I VGDDLFVTN P 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 324 T RL QE GI D K GI ANA I L V KVNQIG S LTETI DTVN LAK R N S Y KNIM SHRSGETED AT IADLAVAL NT GQIKTG SAS RS D R M A 403
Cdd:cd03313 318 E RL KK GI E K KA ANA L L I KVNQIG T LTETI EAIK LAK K N G Y GVVV SHRSGETED TF IADLAVAL GA GQIKTG APC RS E R T A 397
410
....*....|.
gi 522085333 404 KYNQLLRIEEE 414
Cdd:cd03313 398 KYNQLLRIEEE 408
eno
TIGR01060 phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
4-426
0e+00
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain]
Cd Length: 425
Bit Score: 727.62
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 4 I QS I H AR Q ILDSRGNPTVEV D V RT E N G FL GRAAVPSGASTG TH EA V ELRD D DKK V Y M GKGVLKAV S NVNE L I F PEL V G IS 83
Cdd:TIGR01060 1 I VD I R AR E ILDSRGNPTVEV E V IL E D G TF GRAAVPSGASTG ER EA L ELRD G DKK R Y L GKGVLKAV E NVNE I I A PEL I G MD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 84 IFE Q SM ID R I ML ELDGTPNK GR LGANAILGVS L A A AKAAA QEA GLPLYRY I GG V NA NT LPVPMMNI L NGG S HADN SI DFQ 163
Cdd:TIGR01060 81 ATD Q RE ID Q I LI ELDGTPNK SK LGANAILGVS M A V AKAAA DSL GLPLYRY L GG F NA YV LPVPMMNI I NGG A HADN NL DFQ 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 164 EFM V MP AN APSF S EALRMG T E I FH T LK GV LK KM GLAT N VGDEGGFAPN IK SNEEA IQT I IQ AIEKAGY R PGEDV WI A M D A 243
Cdd:TIGR01060 161 EFM I MP VG APSF R EALRMG A E V FH A LK KL LK EK GLAT G VGDEGGFAPN LA SNEEA LEI I VE AIEKAGY K PGEDV AL A L D C 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 244 A S SEFYD A E A G V Y HF K KST g DK LTS S EM AGFWKDW V N KYPI L SIEDG MA E D DW D GW KAQ T DL L K D n K T Q L VGDDLFVTN V 323
Cdd:TIGR01060 241 A A SEFYD E E D G K Y VY K GEN - KQ LTS E EM IEYYEEL V E KYPI I SIEDG LS E E DW E GW AEL T KR L G D - K V Q I VGDDLFVTN T 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 324 TR L Q EGI DK G I AN A IL V K V NQIG S LTET I D TVN LAK RNS Y KNIM SHRSGETED A TIADLAVA L N T GQIKTGS A SRS D R M A 403
Cdd:TIGR01060 319 EI L R EGI EM G V AN S IL I K P NQIG T LTET L D AIE LAK KAG Y TAVI SHRSGETED T TIADLAVA T N A GQIKTGS L SRS E R I A 398
410 420
....*....|....*....|...
gi 522085333 404 KYNQLLRIEEELG ET A YFP G LKF 426
Cdd:TIGR01060 399 KYNQLLRIEEELG DS A RYA G KNS 421
Enolase_C
pfam00113 Enolase, C-terminal TIM barrel domain;
141-426
1.84e-155
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063
Cd Length: 296
Bit Score: 441.15
E-value: 1.84e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 141 T LPVPMMN IL NGGSHA D N SID FQEFM VM P AN APSFSEA L RMG T E IF H T LK G VLK KMG -- L ATNVGDEGGFAPN IK SN E EA 218
Cdd:pfam00113 3 V LPVPMMN VI NGGSHA G N NLA FQEFM IL P TG APSFSEA M RMG A E VY H H LK S VLK AKY gq S ATNVGDEGGFAPN LQ SN K EA 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 219 IQT I IQ AIEKAGY RP ge DVW IAMD A ASSEFY DAEA G V Y H -- FK KSTG D --- KLTS SEM A GFWKDW V N KYPI L SIED GMA E 293
Cdd:pfam00113 83 LDL I VE AIEKAGY KG -- KIK IAMD V ASSEFY NKKD G K Y D ld FK GEKS D ksk KLTS AQL A DLYEEL V K KYPI V SIED PFD E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 294 DDW DG WK AQ T DL L k DN K T Q L VGDDL F VTN VT RL QEG I D K G IANA I L V KVNQIGSLTE T I DT V NL AK RNSYKNIM SHRSGE 373
Cdd:pfam00113 161 DDW EA WK YL T ER L - GD K V Q I VGDDL T VTN PK RL KTA I E K K IANA L L L KVNQIGSLTE S I AA V KM AK DAGWGVMV SHRSGE 239
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 522085333 374 TED A TIADLAV A LN T GQIKTG SAS RS D R M AKYNQLLRIEEELG ET A YFP G LK F 426
Cdd:pfam00113 240 TED T TIADLAV G LN A GQIKTG APC RS E R L AKYNQLLRIEEELG SE A KYA G RS F 292
Name
Accession
Description
Interval
E-value
Eno
COG0148 Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
1-425
0e+00
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain]
Cd Length: 426
Bit Score: 881.66
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 1 MS T I QSI HAR Q ILDSRGNPTVEV D V RT E N G FL GRAAVPSGASTG T HEAVELRD D DK KV Y M GKGVLKAV S NVNE L I F P E L V 80
Cdd:COG0148 1 MS R I EDV HAR E ILDSRGNPTVEV E V TL E D G AV GRAAVPSGASTG S HEAVELRD G DK SR Y L GKGVLKAV E NVNE E I A P A L I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 81 G ISIFE Q SM IDR I M L ELDGTPNK G RLGANAILGVSLA A AKAAA QEA GLPLYRY I GGVNA N TLPVPMMNI L NGG S HADN SI 160
Cdd:COG0148 81 G MDATD Q RA IDR A M I ELDGTPNK S RLGANAILGVSLA V AKAAA AAL GLPLYRY L GGVNA K TLPVPMMNI I NGG A HADN NV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 161 D F QEFM V MP AN APSFSEALRMG T E I FH T LK G VLK KM GL A T N VGDEGGFAPN I KSNEEA IQT I IQ AIEKAGY R PGED VWI A 240
Cdd:COG0148 161 D I QEFM I MP VG APSFSEALRMG A E V FH A LK K VLK EK GL S T A VGDEGGFAPN L KSNEEA LEL I LE AIEKAGY K PGED IAL A 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 241 M D A A S SEFY D ae A G V YH F k K ST G DK LTS S EM AGFWK D W V N KYPI L SIEDG M AEDDWDGWK AQ T DL L K D n K T QLVGDDLFV 320
Cdd:COG0148 241 L D V A A SEFY K -- D G K YH L - K GE G KE LTS E EM IDYYA D L V D KYPI V SIEDG L AEDDWDGWK LL T EK L G D - K V QLVGDDLFV 316
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 321 TN VT RL QE GI DK G I AN A IL V KVNQIG S LTET I D TVN LAKR NS Y KNIM SHRSGETED A TIADLAVA L N T GQIKTGS A SRS D 400
Cdd:COG0148 317 TN PK RL KK GI EE G A AN S IL I KVNQIG T LTET L D AIE LAKR AG Y TAVI SHRSGETED T TIADLAVA T N A GQIKTGS P SRS E 396
410 420
....*....|....*....|....*
gi 522085333 401 R M AKYNQLLRIEEELG ET A YFP G LK 425
Cdd:COG0148 397 R V AKYNQLLRIEEELG DA A RYA G RS 421
eno
PRK00077 enolase; Provisional
1-426
0e+00
enolase; Provisional
Pssm-ID: 234617 [Multi-domain]
Cd Length: 425
Bit Score: 843.60
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 1 MS T I QS I H AR Q ILDSRGNPTVEV D V RT E N G FL GRAAVPSGASTG TH EAVELRD D DK KV Y M GKGVLKAV S NVNE L I F P E L V 80
Cdd:PRK00077 1 MS K I ED I I AR E ILDSRGNPTVEV E V TL E D G AF GRAAVPSGASTG ER EAVELRD G DK SR Y L GKGVLKAV E NVNE E I A P A L I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 81 G ISIFE Q SM ID RI M L ELDGTPNK GR LGANAILGVSLA A AKAAA QEA GLPLYRY I GG V NA NT LPVPMMNI L NGG S HADN SI 160
Cdd:PRK00077 81 G LDALD Q RA ID KA M I ELDGTPNK SK LGANAILGVSLA V AKAAA DSL GLPLYRY L GG P NA KV LPVPMMNI I NGG A HADN NV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 161 D F QEFM V MP AN APSF S EALRMG T E I FHTLK G VLK KM GL A T N VGDEGGFAPN I KSNEEA IQT I IQ AIEKAGY R PGED VWI A 240
Cdd:PRK00077 161 D I QEFM I MP VG APSF K EALRMG A E V FHTLK K VLK EK GL S T A VGDEGGFAPN L KSNEEA LDL I LE AIEKAGY K PGED IAL A 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 241 M D A A S SEFY da EA G V Y HFK kst G DK LTS S EM AGFWKDW V N KYPI L SIEDG MA E D DW D GWK AQ T DL L K D n K T QLVGDDLFV 320
Cdd:PRK00077 241 L D C A A SEFY -- KD G K Y VLE --- G EG LTS E EM IDYLAEL V D KYPI V SIEDG LD E N DW E GWK LL T EK L G D - K V QLVGDDLFV 314
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 321 TN VT RL QE GI D KG I AN A IL V KVNQIG S LTET I D TVN LAKR NS Y KNIM SHRSGETED A TIADLAVA L N T GQIKTGS A SRS D 400
Cdd:PRK00077 315 TN TK RL KK GI E KG A AN S IL I KVNQIG T LTET L D AIE LAKR AG Y TAVV SHRSGETED T TIADLAVA T N A GQIKTGS L SRS E 394
410 420
....*....|....*....|....*.
gi 522085333 401 R M AKYNQLLRIEEELG ET A YFP G L K F 426
Cdd:PRK00077 395 R I AKYNQLLRIEEELG DA A RYA G K K A 420
enolase
cd03313 Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
6-414
0e+00
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain]
Cd Length: 408
Bit Score: 748.54
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 6 S I H AR Q ILDSRGNPTVEV D V R TE N G FL GRAAVPSGASTG T HEAVELRD D DK KV Y M GKGVLKAV S NVNE L I F P E L V G ISIF 85
Cdd:cd03313 1 K I K AR E ILDSRGNPTVEV E V T TE D G GV GRAAVPSGASTG E HEAVELRD G DK SR Y L GKGVLKAV K NVNE I I A P A L I G MDVT 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 86 E Q SM ID RIML ELDGTPNK GR LGANAILGVSLA A AKAAA QEA GLPLYRY I GG VN A NT LPVPM M N IL NGG S HA D N SI DFQEF 165
Cdd:cd03313 81 D Q RA ID KLLI ELDGTPNK SK LGANAILGVSLA V AKAAA AAL GLPLYRY L GG LA A YV LPVPM F N VI NGG A HA G N KL DFQEF 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 166 M VM P AN APSFSEALRMG T E IF HTLK G VLKK M G -- LATNVGDEGGFAPN IK SNEEA IQTIIQ AIEKAGY R PG EDVW IA M D A 243
Cdd:cd03313 161 M IV P VG APSFSEALRMG A E VY HTLK K VLKK K G gl LATNVGDEGGFAPN LS SNEEA LDLLVE AIEKAGY E PG KKIA IA L D V 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 244 A S SEFYD ae A G V Y HFKKST G D KLTS S E MAGFW K DW V N KYPI L SIED GMA EDDW D GW KAQ T DL L K D n K T Q L VGDDLFVTN V 323
Cdd:cd03313 241 A A SEFYD -- E G K Y VYDSDE G K KLTS E E LIDYY K EL V K KYPI V SIED PFD EDDW E GW AKL T AK L G D - K I Q I VGDDLFVTN P 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 324 T RL QE GI D K GI ANA I L V KVNQIG S LTETI DTVN LAK R N S Y KNIM SHRSGETED AT IADLAVAL NT GQIKTG SAS RS D R M A 403
Cdd:cd03313 318 E RL KK GI E K KA ANA L L I KVNQIG T LTETI EAIK LAK K N G Y GVVV SHRSGETED TF IADLAVAL GA GQIKTG APC RS E R T A 397
410
....*....|.
gi 522085333 404 KYNQLLRIEEE 414
Cdd:cd03313 398 KYNQLLRIEEE 408
eno
TIGR01060 phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
4-426
0e+00
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain]
Cd Length: 425
Bit Score: 727.62
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 4 I QS I H AR Q ILDSRGNPTVEV D V RT E N G FL GRAAVPSGASTG TH EA V ELRD D DKK V Y M GKGVLKAV S NVNE L I F PEL V G IS 83
Cdd:TIGR01060 1 I VD I R AR E ILDSRGNPTVEV E V IL E D G TF GRAAVPSGASTG ER EA L ELRD G DKK R Y L GKGVLKAV E NVNE I I A PEL I G MD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 84 IFE Q SM ID R I ML ELDGTPNK GR LGANAILGVS L A A AKAAA QEA GLPLYRY I GG V NA NT LPVPMMNI L NGG S HADN SI DFQ 163
Cdd:TIGR01060 81 ATD Q RE ID Q I LI ELDGTPNK SK LGANAILGVS M A V AKAAA DSL GLPLYRY L GG F NA YV LPVPMMNI I NGG A HADN NL DFQ 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 164 EFM V MP AN APSF S EALRMG T E I FH T LK GV LK KM GLAT N VGDEGGFAPN IK SNEEA IQT I IQ AIEKAGY R PGEDV WI A M D A 243
Cdd:TIGR01060 161 EFM I MP VG APSF R EALRMG A E V FH A LK KL LK EK GLAT G VGDEGGFAPN LA SNEEA LEI I VE AIEKAGY K PGEDV AL A L D C 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 244 A S SEFYD A E A G V Y HF K KST g DK LTS S EM AGFWKDW V N KYPI L SIEDG MA E D DW D GW KAQ T DL L K D n K T Q L VGDDLFVTN V 323
Cdd:TIGR01060 241 A A SEFYD E E D G K Y VY K GEN - KQ LTS E EM IEYYEEL V E KYPI I SIEDG LS E E DW E GW AEL T KR L G D - K V Q I VGDDLFVTN T 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 324 TR L Q EGI DK G I AN A IL V K V NQIG S LTET I D TVN LAK RNS Y KNIM SHRSGETED A TIADLAVA L N T GQIKTGS A SRS D R M A 403
Cdd:TIGR01060 319 EI L R EGI EM G V AN S IL I K P NQIG T LTET L D AIE LAK KAG Y TAVI SHRSGETED T TIADLAVA T N A GQIKTGS L SRS E R I A 398
410 420
....*....|....*....|...
gi 522085333 404 KYNQLLRIEEELG ET A YFP G LKF 426
Cdd:TIGR01060 399 KYNQLLRIEEELG DS A RYA G KNS 421
PTZ00081
PTZ00081 enolase; Provisional
1-423
0e+00
enolase; Provisional
Pssm-ID: 240259 [Multi-domain]
Cd Length: 439
Bit Score: 604.35
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 1 MSTI Q SI H AR Q ILDSRGNPTVEVD VR TE N G FL g RAAVPSGASTG TH EA V ELRD D DK KV Y M GKGVLKAV S NVNE L I F P E L V 80
Cdd:PTZ00081 1 MSTI K SI K AR E ILDSRGNPTVEVD LT TE K G VF - RAAVPSGASTG IY EA L ELRD G DK SR Y L GKGVLKAV E NVNE I I A P A L I 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 81 G ISIFE Q SMI D RI M L E - LDGT P N ----- K GR LGANAIL G VS L A A A K AAA QEA G L PLY R Y IGGVNANT ----- LPVP MM N I 149
Cdd:PTZ00081 80 G KDVTD Q KKL D KL M V E q LDGT K N ewgwc K SK LGANAIL A VS M A V A R AAA AAK G V PLY K Y LAQLAGKP tdkfv LPVP CF N V 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 150 L NGG S HA D N SID FQEFM VM P AN APSF S EALRMG T E IF H T LK G V L K - K M GL - ATNVGDEGGFAPNIK SN EEA IQTIIQ AI E 227
Cdd:PTZ00081 160 I NGG K HA G N KLA FQEFM IA P VG APSF K EALRMG A E VY H S LK S V I K k K Y GL d ATNVGDEGGFAPNIK DP EEA LDLLVE AI K 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 228 KAGY R p G E d V W I A MD A A S SEFYD A E AG VY H -- FK KSTG D --- KLT SS E MAGFWK D W V N KYPI L SIED GMAE DDW DGWKAQ 302
Cdd:PTZ00081 240 KAGY E - G K - V K I C MD V A A SEFYD K E KK VY D ld FK NPNN D ksn KLT GE E LVELYL D L V K KYPI V SIED PFDQ DDW EAYAKL 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 303 T DLLK d N K T Q L VGDDL F VTN V TR LQEG I D K GIA NA I L V KVNQIG SL TE T I DTVN LA KR N SYKNIM SHRSGETED AT IADL 382
Cdd:PTZ00081 318 T AAIG - Q K V Q I VGDDL L VTN P TR IKKA I E K KAC NA L L L KVNQIG TV TE A I EAAK LA QK N GWGVMV SHRSGETED TF IADL 396
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 522085333 383 A V A L N TGQIKTG SAS RS D R M AKYNQLLRIEEELG ET A YFP G 423
Cdd:PTZ00081 397 V V G L G TGQIKTG APC RS E R L AKYNQLLRIEEELG SN A VYA G 437
PLN00191
PLN00191 enolase
1-426
0e+00
enolase
Pssm-ID: 215095 [Multi-domain]
Cd Length: 457
Bit Score: 569.34
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 1 M S TI QSIH ARQI L DSRGNPTVEVD VR T EN G FL g RAAVPSGASTG TH EA V ELRD D DK K v Y M GKGVLKAV S NVNE L I F P E L V 80
Cdd:PLN00191 25 M A TI TKVK ARQI I DSRGNPTVEVD LH T SK G MF - RAAVPSGASTG IY EA L ELRD G DK D - Y L GKGVLKAV K NVNE I I A P A L I 102
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 81 G ISIFE Q SM ID RI MLELDGTPNKG R LGANAIL G VSLA AA KA A A Q E A G L PLY RY I --- G G VNANT LPVP MM N IL NGGSHA D 157
Cdd:PLN00191 103 G MDPTD Q TQ ID NF MLELDGTPNKG K LGANAIL A VSLA VC KA G A A E K G V PLY KH I adl A G NKKLV LPVP AF N VI NGGSHA G 182
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 158 N SIDF QEFM VM P AN A P SF S EA LR MG T E IF H T LK G V L KK M -- GL A T NVGDEGGFAPNI KS N E E AIQTIIQ AIEKAGY R pg E 235
Cdd:PLN00191 183 N KLAM QEFM IL P VG A S SF K EA MQ MG S E VY H H LK A V I KK K yg QD A C NVGDEGGFAPNI QD N K E GLELLKE AIEKAGY T -- G 260
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 236 DVW I A MD A A S SEFY DAE a GV Y -- H FK --- KSTGD K LTSS E MAGFW K DW V NK YPI L SIED GMAE DDW DG W KAQ T D L lkd NK 310
Cdd:PLN00191 261 KIK I G MD V A A SEFY TKD - KK Y dl D FK een NDGSN K KSGD E LIDLY K EF V SD YPI V SIED PFDQ DDW EH W AKL T S L --- ED 336
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 311 T Q L VGDDL F VTN VT R LQEG I DKGIA NA I L V KVNQIG SL TE T I DT V NLA K RNSYKNIM SHRSGETED AT IADLAV A L N TGQ 390
Cdd:PLN00191 337 V Q I VGDDL L VTN PK R VAKA I QEKAC NA L L L KVNQIG TV TE S I EA V KMS K AAGWGVMT SHRSGETED SF IADLAV G L A TGQ 416
410 420 430
....*....|....*....|....*....|....*.
gi 522085333 391 IKTG SAS RS D R M AKYNQLLRIEEELG ET A YFP G LK F 426
Cdd:PLN00191 417 IKTG APC RS E R L AKYNQLLRIEEELG DE A VYA G EN F 452
Enolase_C
pfam00113 Enolase, C-terminal TIM barrel domain;
141-426
1.84e-155
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063
Cd Length: 296
Bit Score: 441.15
E-value: 1.84e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 141 T LPVPMMN IL NGGSHA D N SID FQEFM VM P AN APSFSEA L RMG T E IF H T LK G VLK KMG -- L ATNVGDEGGFAPN IK SN E EA 218
Cdd:pfam00113 3 V LPVPMMN VI NGGSHA G N NLA FQEFM IL P TG APSFSEA M RMG A E VY H H LK S VLK AKY gq S ATNVGDEGGFAPN LQ SN K EA 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 219 IQT I IQ AIEKAGY RP ge DVW IAMD A ASSEFY DAEA G V Y H -- FK KSTG D --- KLTS SEM A GFWKDW V N KYPI L SIED GMA E 293
Cdd:pfam00113 83 LDL I VE AIEKAGY KG -- KIK IAMD V ASSEFY NKKD G K Y D ld FK GEKS D ksk KLTS AQL A DLYEEL V K KYPI V SIED PFD E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 294 DDW DG WK AQ T DL L k DN K T Q L VGDDL F VTN VT RL QEG I D K G IANA I L V KVNQIGSLTE T I DT V NL AK RNSYKNIM SHRSGE 373
Cdd:pfam00113 161 DDW EA WK YL T ER L - GD K V Q I VGDDL T VTN PK RL KTA I E K K IANA L L L KVNQIGSLTE S I AA V KM AK DAGWGVMV SHRSGE 239
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 522085333 374 TED A TIADLAV A LN T GQIKTG SAS RS D R M AKYNQLLRIEEELG ET A YFP G LK F 426
Cdd:pfam00113 240 TED T TIADLAV G LN A GQIKTG APC RS E R L AKYNQLLRIEEELG SE A KYA G RS F 292
Enolase_N
pfam03952 Enolase, N-terminal domain;
4-134
5.27e-80
Enolase, N-terminal domain;
Pssm-ID: 461105 [Multi-domain]
Cd Length: 131
Bit Score: 242.67
E-value: 5.27e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 4 I QSIH AR Q ILDSRGNPTVEV D V RT E N G FL GRAAVPSGASTG T HEAVELRD D DK KV Y M GKGVLKAV S NVNE L I F P E L V G IS 83
Cdd:pfam03952 1 I TKVK AR E ILDSRGNPTVEV E V TL E D G TF GRAAVPSGASTG E HEAVELRD G DK SR Y G GKGVLKAV E NVNE I I A P A L I G MD 80
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 522085333 84 IFE Q SM IDR IML ELDGT P NK GR LGANAILGVSLA A AKAAA QEA GLPLYRY I 134
Cdd:pfam03952 81 ATD Q RA IDR ALI ELDGT E NK SK LGANAILGVSLA V AKAAA AAL GLPLYRY L 131
PRK08350
PRK08350 hypothetical protein; Provisional
1-417
6.49e-24
hypothetical protein; Provisional
Pssm-ID: 169397 [Multi-domain]
Cd Length: 341
Bit Score: 101.81
E-value: 6.49e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 1 M ST I QS I HA R QILDSR G NPT VEVDV R T EN GF l GR A A V P S gastgtheavelr D DDKKV Y MGKG v LK AVS N V N E L I F PEL V 80
Cdd:PRK08350 1 M TV I EN I IG R VAVLRG G KYS VEVDV I T DS GF - GR F A A P I ------------- D ENPSL Y IAEA - HR AVS E V D E I I G PEL I 65
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 81 G ISIF EQ SM ID RIML E L DGT PNKGRL GAN AI L G VS L A A AKAAA QEAGL PLY R YIGG VNANT LPVP MMNILNG gshadnsi 160
Cdd:PRK08350 66 G FDAS EQ EL ID SYLW E I DGT EDFSHI GAN TA L A VS V A V AKAAA NSKNM PLY S YIGG TFTTE LPVP ILEFAED -------- 137
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 161 DFQ E FM V M panapsfsea L R MGT EI FHTLKG V L K KMG latnvgdeggfapni K S N E EAIQTIIQ A I EKAG YRP G ED V WI a 240
Cdd:PRK08350 138 ENF E YY V L ---------- V R DLM EI TDVVDA V N K ILE --------------- N S K E VSLEGLSK A S EKAG DEL G LE V AL - 191
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 241 mdaassefydaea G VYHFKKSTGD K LTSS emagfwkdw V NKYP I LS I EDGMA E DDWDGWK A Q T dllkd NKTQLV G DD LF v 320
Cdd:PRK08350 192 ------------- G IAQKREMETE K VLNL --------- V EDNN I AY I KPIGD E ELFLELI A G T ----- HGVFID G EY LF - 243
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 321 tnvt R LQEGI D KGIA NA ILV K VNQI G S LT ETIDT VN LA K RNSYKN I MSHRSG E TE D ATIAD LAV A L NTGQI ktgs ASRS D 400
Cdd:PRK08350 244 ---- R TRNIL D RRYY NA LSI K PINL G T LT DLYNL VN DV K SERITP I LAEAKY E SA D EALPH LAV G L RCPAM ---- LIHK D 315
410
....*....|....*..
gi 522085333 401 RMA K Y N Q L L RI E E E LGE 417
Cdd:PRK08350 316 SVE K I N E L N RI A E D LGE 332
enolase_like
cd00308 Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ...
214-393
6.93e-11
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.
Pssm-ID: 238188 [Multi-domain]
Cd Length: 229
Bit Score: 61.96
E-value: 6.93e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 214 SNE E AIQTIIQ A I ekagyrp G E D VWI A M DA ASS efydaeagvyhfkkstgdk L T SS E MAGFWKD w VN KY PILS IE DGM A E 293
Cdd:cd00308 79 GSI E RVRAVRE A F ------- G P D ARL A V DA NGA ------------------- W T PK E AIRLIRA - LE KY GLAW IE EPC A P 131
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522085333 294 DD WD G WK A QTDLL kdn KTQLVG D DLFV T NVTR L q E GIDK G IANAILV K VNQI G S LTE TIDTVN LA KRNS y KNI M S H RSG E 373
Cdd:cd00308 132 DD LE G YA A LRRRT --- GIPIAA D ESVT T VDDA L - E ALEL G AVDILQI K PTRV G G LTE SRRAAD LA EAFG - IRV M V H GTL E 206
170 180
....*....|....*....|...
gi 522085333 374 TE -- D A TIAD LA V AL - N TGQ I K T 393
Cdd:cd00308 207 SS ig T A AALH LA A AL p N DRA I E T 229
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
