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Conserved domains on  [gi|522821568|ref|WP_020734307|]
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class II fructose-bisphosphate aldolase [Sorangium cellulosum]

Protein Classification

class II fructose-bisphosphate aldolase( domain architecture ID 10013149)

class II fructose-1,6-bisphosphate (FBP) aldolase catalyzes the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate

EC:  4.1.2.13
Gene Ontology:  GO:0008270|GO:0004332|GO:0016832

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 8-354 0e+00

fructose-bisphosphate aldolase; Provisional


:

Pssm-ID: 236406  Cd Length: 350  Bit Score: 619.12  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568   8 PGVITGSALQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFLDNKGEKAAIAGAIAG 87
Cdd:PRK09197   1 PGVATGEDYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGKGVKDDGQGAAVLGAIAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  88 AHYVRNLAEAYGVPVVLHTDHAAKKLLPWVDGMLEHGKKFFEKNGEPLFSSHMLDLSEEPLHENLEICQKYLRQMAAIKM 167
Cdd:PRK09197  81 AKHVHEVAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAAGGKPLFSSHMIDLSEEPLEENIEICSKYLERMAKAGM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 168 TLEIELGVTGGEEDGVDNSGIDNAKLYTQPAEVLAAYDALKPI-GNFTVAASFGNTHGVYKPGNVQLRPPILKNSQDAIQ 246
Cdd:PRK09197 161 TLEIELGVTGGEEDGVDNSHEDNSKLYTQPEDVLYAYEALGKIsGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 247 KERKTGAKPVDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDKGAYLKSQLGNPEGEDKPNKKYID 326
Cdd:PRK09197 241 KKFGLPAKPFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDYLQGQVGNPEGEDKPNKKYYD 320

                        330       340
                 ....*....|....*....|....*...
gi 522821568 327 PRGWLHLGEKGLAARLVEAFKDLNSFDK 354
Cdd:PRK09197 321 PRVWLRAAEASMAARLEEAFEDLNSIGV 348
 
Name Accession Description Interval E-value
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 8-354 0e+00

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 619.12  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568   8 PGVITGSALQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFLDNKGEKAAIAGAIAG 87
Cdd:PRK09197   1 PGVATGEDYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGKGVKDDGQGAAVLGAIAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  88 AHYVRNLAEAYGVPVVLHTDHAAKKLLPWVDGMLEHGKKFFEKNGEPLFSSHMLDLSEEPLHENLEICQKYLRQMAAIKM 167
Cdd:PRK09197  81 AKHVHEVAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAAGGKPLFSSHMIDLSEEPLEENIEICSKYLERMAKAGM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 168 TLEIELGVTGGEEDGVDNSGIDNAKLYTQPAEVLAAYDALKPI-GNFTVAASFGNTHGVYKPGNVQLRPPILKNSQDAIQ 246
Cdd:PRK09197 161 TLEIELGVTGGEEDGVDNSHEDNSKLYTQPEDVLYAYEALGKIsGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 247 KERKTGAKPVDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDKGAYLKSQLGNPEGEDKPNKKYID 326
Cdd:PRK09197 241 KKFGLPAKPFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDYLQGQVGNPEGEDKPNKKYYD 320

                        330       340
                 ....*....|....*....|....*...
gi 522821568 327 PRGWLHLGEKGLAARLVEAFKDLNSFDK 354
Cdd:PRK09197 321 PRVWLRAAEASMAARLEEAFEDLNSIGV 348
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 13-354 0e+00

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 546.58  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  13 GSALQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFLDNKGEKAAIAGAIAGAHYVR 92
Cdd:cd00946    1 GDDVLKLFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQFSNGGAAFYAGKGLKNEKQKASIAGAIAAAHHVR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  93 NLAEAYGVPVVLHTDHAAKKLLPWVDGMLEHGKKFFEKNGEPLFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIE 172
Cdd:cd00946   81 SMAEHYGVPVVLHTDHCAKKLLPWFDGLLEADEEYFKQHGEPLFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEME 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 173 LGVTGGEEDGVDNSGIDNAKLYTQPAEVLAAYDALKPI-GNFTVAASFGNTHGVYKPGNVQLRPPILKNSQDAIQKERKT 251
Cdd:cd00946  161 IGITGGEEDGVDNSGVDNAELYTQPEDVWYVYEALSKIsPNFSIAAAFGNVHGVYKPGNVKLQPEILGEHQDYVREKLGL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 252 G-AKPVDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDKGAYLKSQLGNPEGEDKPNKKYIDPRGW 330
Cdd:cd00946  241 AdDKPLYFVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLKNEDYLQGQIGNPEGPDKPNKKYYDPRVW 320

                        330       340
                 ....*....|....*....|....
gi 522821568 331 LHLGEKGLAARLVEAFKDLNSFDK 354
Cdd:cd00946  321 LREGEKSMVARVKKAFEDLNSVNK 344
FruBisAldo_II_A TIGR01520
fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are ...
 5-354 0e+00

fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are class II examples of the glycolytic enzyme fructose-bisphosphate aldolase (FBA). This model represents one of two deeply split, architecturally distinct clades of the family that includes class II fructose-bisphosphate aldolases, tagatose-bisphosphate aldolases, and related uncharacterized proteins. This family is well-conserved and includes characterized FBA from Saccharomyces cerevisiae, Escherichia coli, and Corynebacterium glutamicum. Proteins outside the scope of this model may also be designated as class II fructose-bisphosphate aldolases, but are well separated in an alignment-based phylogenetic tree. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130583  Cd Length: 357  Bit Score: 508.98  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568    5 KLKPGVITGSALQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFLDNKGEKAAIAG- 83
Cdd:TIGR01520   4 FVKPGVITGDDVHKLFQYAKENNFAIPAINCTSSSTINAALEAAADVKSPIIIQFSNGGAAFIAGKGVKDEVPQGASILg 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568   84 AIAGAHYVRNLAEAYGVPVVLHTDHAAKKLLPWVDGMLEHGKKFFEKNGEPLFSSHMLDLSEEPLHENLEICQKYLRQMA 163
Cdd:TIGR01520  84 AIAGAHHVHSIAEHYGVPVVLHTDHCAKKLLPWVDGLLEAGEKYFSAHGKPLFSSHMIDLSEEPIEENIEICVKYLKRMA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  164 AIKMTLEIELGVTGGEEDGVDNSGIDNAKLYTQPAEVLAAYDALKPI-GNFTVAASFGNTHGVYKPGNVQLRPPILKNSQ 242
Cdd:TIGR01520 164 KIKMWLEIEIGITGGEEDGVDNSHMDAEALYTQPEDVYYAYEELSKIsPNFSIAAAFGNVHGVYKPGNVKLTPDILADGQ 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  243 DAIQKerKTG---AKPVDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDKGAYLKSQLGNPEGEDK 319
Cdd:TIGR01520 244 EYVSE--KLGlpaAKPLFFVFHGGSGSTKQEIKEALSYGVVKMNIDTDTQWAYWEGILNYYKNNEDYLQGQLGNPKGPDK 321

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 522821568  320 PNKKYIDPRGWLHLGEKGLAARLVEAFKDLNSFDK 354
Cdd:TIGR01520 322 PNKKFYDPRVWLREGEKSMKARVEKACQELNNINV 356
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 16-354 1.87e-109

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 320.88  E-value: 1.87e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  16 LQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFLdnkgekaaiagaiagAHYVRNLA 95
Cdd:COG0191    5 LKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGLEYL---------------AAMVRAAA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  96 EAYGVPVVLHTDHAAkkllpwvdgmlehGKKFFEKNGEPLFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGV 175
Cdd:COG0191   70 EEASVPVALHLDHGA-------------SFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGV 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 176 TGGEEDGVDNSgiDNAKLYTQPAEVLAAYDALkpiGNFTVAASFGNTHGVYKpGNVQLRPPILKNSQDAIqkerktgakP 255
Cdd:COG0191  137 VGGEEDGVDVD--DAEALYTDPEEAAEFVEET---GVDALAVAIGTVHGVYK-GEPKLDFDRLKEIREAV---------P 201

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 256 VDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMddkgaylksqlgnpegEDKPNKkyIDPRGWLHLGE 335
Cdd:COG0191  202 VPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVREYL----------------AENPDK--YDPRKYLKPAR 263

                        330
                 ....*....|....*....
gi 522821568 336 KGLAARLVEAFKDLNSFDK 354
Cdd:COG0191  264 EAMKEVVKEKIRLFGSAGK 282
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
16-354 1.03e-108

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 318.97  E-value: 1.03e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568   16 LQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFldnkgekaaiagaIAGAHYVRNLA 95
Cdd:pfam01116   3 LKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKYAGGA-------------EALAALVRAAA 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568   96 EAYGVPVVLHTDHAAKkllpwVDGMLEHGKKffekngepLFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGV 175
Cdd:pfam01116  70 EAAGVPVALHLDHGAS-----FELIKEAIEA--------GFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGR 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  176 TGGEEDGVdnsgIDNAKLYTQPAEVLAAYDALkpiGNFTVAASFGNTHGVYKPGNvQLRPPILKNSQDAIqkerktgakP 255
Cdd:pfam01116 137 IGGEEDGV----VVDEKLYTDPEEAAEFVEAT---GVDALAVAIGNVHGVYKPGP-KLDFDRLKEIQEAV---------P 199

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  256 VDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDKgaylksqlgnpegedkpnkkyiDPRGWLHLGE 335
Cdd:pfam01116 200 VPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTAAVREYPPNK----------------------DPRKYLRPAE 257

                         330
                  ....*....|....*....
gi 522821568  336 KGLAARLVEAFKDLNSFDK 354
Cdd:pfam01116 258 EAMKEVVKEKIRLFGSAGK 276
 
Name Accession Description Interval E-value
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 8-354 0e+00

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 619.12  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568   8 PGVITGSALQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFLDNKGEKAAIAGAIAG 87
Cdd:PRK09197   1 PGVATGEDYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGKGVKDDGQGAAVLGAIAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  88 AHYVRNLAEAYGVPVVLHTDHAAKKLLPWVDGMLEHGKKFFEKNGEPLFSSHMLDLSEEPLHENLEICQKYLRQMAAIKM 167
Cdd:PRK09197  81 AKHVHEVAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAAGGKPLFSSHMIDLSEEPLEENIEICSKYLERMAKAGM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 168 TLEIELGVTGGEEDGVDNSGIDNAKLYTQPAEVLAAYDALKPI-GNFTVAASFGNTHGVYKPGNVQLRPPILKNSQDAIQ 246
Cdd:PRK09197 161 TLEIELGVTGGEEDGVDNSHEDNSKLYTQPEDVLYAYEALGKIsGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 247 KERKTGAKPVDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDKGAYLKSQLGNPEGEDKPNKKYID 326
Cdd:PRK09197 241 KKFGLPAKPFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDYLQGQVGNPEGEDKPNKKYYD 320

                        330       340
                 ....*....|....*....|....*...
gi 522821568 327 PRGWLHLGEKGLAARLVEAFKDLNSFDK 354
Cdd:PRK09197 321 PRVWLRAAEASMAARLEEAFEDLNSIGV 348
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 13-354 0e+00

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 546.58  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  13 GSALQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFLDNKGEKAAIAGAIAGAHYVR 92
Cdd:cd00946    1 GDDVLKLFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQFSNGGAAFYAGKGLKNEKQKASIAGAIAAAHHVR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  93 NLAEAYGVPVVLHTDHAAKKLLPWVDGMLEHGKKFFEKNGEPLFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIE 172
Cdd:cd00946   81 SMAEHYGVPVVLHTDHCAKKLLPWFDGLLEADEEYFKQHGEPLFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEME 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 173 LGVTGGEEDGVDNSGIDNAKLYTQPAEVLAAYDALKPI-GNFTVAASFGNTHGVYKPGNVQLRPPILKNSQDAIQKERKT 251
Cdd:cd00946  161 IGITGGEEDGVDNSGVDNAELYTQPEDVWYVYEALSKIsPNFSIAAAFGNVHGVYKPGNVKLQPEILGEHQDYVREKLGL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 252 G-AKPVDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDKGAYLKSQLGNPEGEDKPNKKYIDPRGW 330
Cdd:cd00946  241 AdDKPLYFVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLKNEDYLQGQIGNPEGPDKPNKKYYDPRVW 320

                        330       340
                 ....*....|....*....|....
gi 522821568 331 LHLGEKGLAARLVEAFKDLNSFDK 354
Cdd:cd00946  321 LREGEKSMVARVKKAFEDLNSVNK 344
FruBisAldo_II_A TIGR01520
fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are ...
 5-354 0e+00

fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are class II examples of the glycolytic enzyme fructose-bisphosphate aldolase (FBA). This model represents one of two deeply split, architecturally distinct clades of the family that includes class II fructose-bisphosphate aldolases, tagatose-bisphosphate aldolases, and related uncharacterized proteins. This family is well-conserved and includes characterized FBA from Saccharomyces cerevisiae, Escherichia coli, and Corynebacterium glutamicum. Proteins outside the scope of this model may also be designated as class II fructose-bisphosphate aldolases, but are well separated in an alignment-based phylogenetic tree. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130583  Cd Length: 357  Bit Score: 508.98  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568    5 KLKPGVITGSALQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFLDNKGEKAAIAG- 83
Cdd:TIGR01520   4 FVKPGVITGDDVHKLFQYAKENNFAIPAINCTSSSTINAALEAAADVKSPIIIQFSNGGAAFIAGKGVKDEVPQGASILg 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568   84 AIAGAHYVRNLAEAYGVPVVLHTDHAAKKLLPWVDGMLEHGKKFFEKNGEPLFSSHMLDLSEEPLHENLEICQKYLRQMA 163
Cdd:TIGR01520  84 AIAGAHHVHSIAEHYGVPVVLHTDHCAKKLLPWVDGLLEAGEKYFSAHGKPLFSSHMIDLSEEPIEENIEICVKYLKRMA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  164 AIKMTLEIELGVTGGEEDGVDNSGIDNAKLYTQPAEVLAAYDALKPI-GNFTVAASFGNTHGVYKPGNVQLRPPILKNSQ 242
Cdd:TIGR01520 164 KIKMWLEIEIGITGGEEDGVDNSHMDAEALYTQPEDVYYAYEELSKIsPNFSIAAAFGNVHGVYKPGNVKLTPDILADGQ 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  243 DAIQKerKTG---AKPVDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDKGAYLKSQLGNPEGEDK 319
Cdd:TIGR01520 244 EYVSE--KLGlpaAKPLFFVFHGGSGSTKQEIKEALSYGVVKMNIDTDTQWAYWEGILNYYKNNEDYLQGQLGNPKGPDK 321

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 522821568  320 PNKKYIDPRGWLHLGEKGLAARLVEAFKDLNSFDK 354
Cdd:TIGR01520 322 PNKKFYDPRVWLREGEKSMKARVEKACQELNNINV 356
FTBP_aldolase_II cd00453
Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1, ...
 17-353 2.71e-123

Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to yield fructose-1,6-bisphosphate. TBP-aldolase is tetrameric and produces tagarose-1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. Although structurally similar, the class I aldolases use a different mechanism and are believed to have an independent evolutionary origin.


Pssm-ID: 238255  Cd Length: 340  Bit Score: 358.35  E-value: 2.71e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  17 QELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFLDNKGEKAAIAGAIAG-AHYVRNLA 95
Cdd:cd00453    2 QKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAAILGAISgAHHVHQMA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  96 EAYGVPVVLHTDHAAKKLLPWVDGMLEHGKKFFEKNGEPLFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGV 175
Cdd:cd00453   82 EHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELGC 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 176 TGGEEDGVDNSGIDNAKLYTQPAEVLAAYDALKPIGN-FTVAASFGNTHGVYKPGNVQLRPPILKNSQDAIQKERKTGAK 254
Cdd:cd00453  162 TGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPrFTIAASFGNVHGVYKKGNVVLTPTILRDSQEYVSKKHNLPHN 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 255 PVDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDKGAYLKSQLGNPEGEDKPNKKYIDPRGWLHLG 334
Cdd:cd00453  242 SLNFVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVWLRAG 321

                        330
                 ....*....|....*....
gi 522821568 335 EKGLAARLVEAFKDLNSFD 353
Cdd:cd00453  322 QTSMIARLEKAFQELNAID 340
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 16-354 1.87e-109

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 320.88  E-value: 1.87e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  16 LQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFLdnkgekaaiagaiagAHYVRNLA 95
Cdd:COG0191    5 LKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGLEYL---------------AAMVRAAA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  96 EAYGVPVVLHTDHAAkkllpwvdgmlehGKKFFEKNGEPLFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGV 175
Cdd:COG0191   70 EEASVPVALHLDHGA-------------SFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGV 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 176 TGGEEDGVDNSgiDNAKLYTQPAEVLAAYDALkpiGNFTVAASFGNTHGVYKpGNVQLRPPILKNSQDAIqkerktgakP 255
Cdd:COG0191  137 VGGEEDGVDVD--DAEALYTDPEEAAEFVEET---GVDALAVAIGTVHGVYK-GEPKLDFDRLKEIREAV---------P 201

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 256 VDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMddkgaylksqlgnpegEDKPNKkyIDPRGWLHLGE 335
Cdd:COG0191  202 VPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVREYL----------------AENPDK--YDPRKYLKPAR 263

                        330
                 ....*....|....*....
gi 522821568 336 KGLAARLVEAFKDLNSFDK 354
Cdd:COG0191  264 EAMKEVVKEKIRLFGSAGK 282
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
16-354 1.03e-108

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 318.97  E-value: 1.03e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568   16 LQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFldnkgekaaiagaIAGAHYVRNLA 95
Cdd:pfam01116   3 LKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKYAGGA-------------EALAALVRAAA 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568   96 EAYGVPVVLHTDHAAKkllpwVDGMLEHGKKffekngepLFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGV 175
Cdd:pfam01116  70 EAAGVPVALHLDHGAS-----FELIKEAIEA--------GFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGR 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  176 TGGEEDGVdnsgIDNAKLYTQPAEVLAAYDALkpiGNFTVAASFGNTHGVYKPGNvQLRPPILKNSQDAIqkerktgakP 255
Cdd:pfam01116 137 IGGEEDGV----VVDEKLYTDPEEAAEFVEAT---GVDALAVAIGNVHGVYKPGP-KLDFDRLKEIQEAV---------P 199

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  256 VDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDKgaylksqlgnpegedkpnkkyiDPRGWLHLGE 335
Cdd:pfam01116 200 VPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTAAVREYPPNK----------------------DPRKYLRPAE 257

                         330
                  ....*....|....*....
gi 522821568  336 KGLAARLVEAFKDLNSFDK 354
Cdd:pfam01116 258 EAMKEVVKEKIRLFGSAGK 276
cbbA TIGR00167
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ...
 11-354 7.49e-104

ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 272938  Cd Length: 288  Bit Score: 306.94  E-value: 7.49e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568   11 ITGSALQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKfldnkgekaaiaGAIAGAHY 90
Cdd:TIGR00167   1 MMLVDVKELLQDAKEEGYAIPAFNINNLETINAVLEAAAEEKSPVIIQFSNGAAKYIAGL------------GAISAMVK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568   91 VRNLAEAYGVPVVLHTDHAAkkllpwvdgmlehGKKFFEKNGEPLFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLE 170
Cdd:TIGR00167  69 AMSEAYPYGVPVALHLDHGA-------------SEEDCAQAVKAGFSSVMIDGSHEPFEENIELTKKVVERAHKMGVSVE 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  171 IELGVTGGEEDGVdnSGIDNAKLYTQPAEvlaaYDALKPI-GNFTVAASFGNTHGVYKPGNVQLRPPILKNSQDAIQker 249
Cdd:TIGR00167 136 AELGTLGGEEDGV--SVADESALYTDPEE----AKEFVKLtGVDSLAAAIGNVHGVYKGEPKGLDFERLEEIQKYVN--- 206

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  250 ktgakpVDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMddkgaylksqlgnpegedKPNKKYIDPRG 329
Cdd:TIGR00167 207 ------LPLVLHGGSGIPDEEIKKAISLGVVKVNIDTELQIAFAAAVRNYY------------------AENKDYYDPRV 262

                         330       340
                  ....*....|....*....|....*
gi 522821568  330 WLHLGEKGLAARLVEAFKDLNSFDK 354
Cdd:TIGR00167 263 WLRPGEKAMKEVVLEKIKLFGSANK 287
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 29-351 3.64e-51

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 171.56  E-value: 3.64e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  29 ALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFLdnkgekaaiagaiagAHYVRNLAEAYGVPVVLHTDH 108
Cdd:cd00947   14 AVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAGLELL---------------VAMVKAAAERASVPVALHLDH 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 109 AAKkllpwvdgmLEHGKKFFEkNGeplFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGVTGGEEDGVdnsgI 188
Cdd:cd00947   79 GSS---------FELIKRAIR-AG---FSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGV----V 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 189 DNAKLYTQPAEVLAAY-----DALkpignftvAASFGNTHGVYKPGNVQLRPPILKNSQDAIqkerktgakPVDFVFHGG 263
Cdd:cd00947  142 GDEGLLTDPEEAEEFVeetgvDAL--------AVAIGTSHGAYKGGEPKLDFDRLKEIAERV---------NVPLVLHGG 204

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 264 SGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDkgaylksqlgnpegedkpNKKYIDPRGWLHLGEKGLAARLV 343
Cdd:cd00947  205 SGIPDEQIRKAIKLGVCKININTDLRLAFTAALREYLAE------------------NPKEFDPRKYLAPAIEAVKEVVK 266


                 ....*...
gi 522821568 344 EAFKDLNS 351
Cdd:cd00947  267 HKMELFGS 274
PRK12857 PRK12857
class II fructose-1,6-bisphosphate aldolase;
29-328 7.49e-30

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 237235  Cd Length: 284  Bit Score: 115.59  E-value: 7.49e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  29 ALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFfAGkfLDnkgekaaiagaiAGAHYVRNLAEAYGVPVVLHtdh 108
Cdd:PRK12857  19 AVGAFNCNNMEIVQAIVAAAEAEKSPVIIQASQGAIKY-AG--IE------------YISAMVRTAAEKASVPVALH--- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 109 aakkllpwvdgmLEHGKKFFE-----KNGeplFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGVTGGEEDGV 183
Cdd:PRK12857  81 ------------LDHGTDFEQvmkciRNG---FTSVMIDGSKLPLEENIALTKKVVEIAHAVGVSVEAELGKIGGTEDDI 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 184 DNSgiDNAKLYTQPAEvlaAYDALKPIGNFTVAASFGNTHGVYKpgnvqLRPpilKNSQDAIQKERKTGAKPVdfVFHGG 263
Cdd:PRK12857 146 TVD--EREAAMTDPEE---ARRFVEETGVDALAIAIGTAHGPYK-----GEP---KLDFDRLAKIKELVNIPI--VLHGS 210

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 522821568 264 SGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDkgaylksqlgnpegedkpNKKYIDPR 328
Cdd:PRK12857 211 SGVPDEAIRKAISLGVRKVNIDTNIREAFVARLREVLEK------------------NPDEIDPR 257
PRK07709 PRK07709
fructose-bisphosphate aldolase; Provisional
 41-354 1.35e-28

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 169068  Cd Length: 285  Bit Score: 112.45  E-value: 1.35e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  41 TVAALQAAREAKSPVIIQFSNGGAHFFAGkfldnkgekaaiagAIAGAHYVRNLAEAYG--VPVVLHTDHAAKkllpwvd 118
Cdd:PRK07709  31 TQAILAAAEEEKSPVILGVSEGAARHMTG--------------FKTVVAMVKALIEEMNitVPVAIHLDHGSS------- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 119 gmlehgkkfFEKNGEPL---FSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGVTGGEEDGVDNSGIdnakLYT 195
Cdd:PRK07709  90 ---------FEKCKEAIdagFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVGGQEDDVIAEGV----IYA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 196 QPAEvlaAYDALKPIGNFTVAASFGNTHGVYKpGNVQLRPPILKNSQDaiqkerKTGakpVDFVFHGGSGSSPEEIREAV 275
Cdd:PRK07709 157 DPAE---CKHLVEATGIDCLAPALGSVHGPYK-GEPNLGFAEMEQVRD------FTG---VPLVLHGGTGIPTADIEKAI 223

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 522821568 276 SYGVIKMNIDTDTQWAFTQPIKKYMDDkgaylksqlgnpegedkpNKKYIDPRGWLHLGEKGLAARLVEAFKDLNSFDK 354
Cdd:PRK07709 224 SLGTSKINVNTENQIEFTKAVREVLNK------------------DQEVYDPRKFIGPGRDAIKATVIGKIREFGSNGK 284
PRK08185 PRK08185
hypothetical protein; Provisional
 16-354 1.72e-28

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 112.13  E-value: 1.72e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  16 LQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNG-----GAHFFAgkfldnkgekaaiagaiagahY 90
Cdd:PRK08185   1 MKELLKVAKEHQFAVGAFNVADSCFLRAVVEEAEANNAPAIIAIHPNeldflGDNFFA---------------------Y 59

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  91 VRNLAEAYGVPVVLHTDHAAKkllpwvdgmLEHGKKFFeKNGeplFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLE 170
Cdd:PRK08185  60 VRERAKRSPVPFVIHLDHGAT---------IEDVMRAI-RCG---FTSVMIDGSLLPYEENVALTKEVVELAHKVGVSVE 126

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 171 IELGvTGGEEDGVDNSGIDNAkLYTQPAEvlaAYDALKPIGNFTVAASFGNTHGVY-KPGNVQLRPPILKNSQDAIQker 249
Cdd:PRK08185 127 GELG-TIGNTGTSIEGGVSEI-IYTDPEQ---AEDFVSRTGVDTLAVAIGTAHGIYpKDKKPELQMDLLKEINERVD--- 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 250 ktgakpVDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDkgaylksqlgNPEGEDkPNKKYIDPRG 329
Cdd:PRK08185 199 ------IPLVLHGGSANPDAEIAESVQLGVGKINISSDMKYAFFKKVREILSD----------NPSLYE-PNQIYPSAIE 261

                        330       340
                 ....*....|....*....|....*..
gi 522821568 330 wlhlgekglAARLVEAFK-DL-NSFDK 354
Cdd:PRK08185 262 ---------AAKEVVRHKmDLfNSTGK 279
PRK07084 PRK07084
class II fructose-1,6-bisphosphate aldolase;
17-303 8.91e-26

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180829  Cd Length: 321  Bit Score: 105.19  E-value: 8.91e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  17 QELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAGKFLDNKGEKAAIagaiagahYVRNLAe 96
Cdd:PRK07084  13 REMFAKAVKGGYAIPAYNFNNMEQLQAIIQACVETKSPVILQVSKGARKYANATLLRYMAQGAVE--------YAKELG- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  97 aYGVPVVLHTDHAAKkllpwvdgmLEHGKKFFEKNgeplFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGVT 176
Cdd:PRK07084  84 -CPIPIVLHLDHGDS---------FELCKDCIDSG----FSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVL 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 177 GGEEDGVdnsgIDNAKLYTQPAEVLaayDALKPIGNFTVAASFGNTHGVYK--PGnvQLRPPILKNSQDAIQKE------ 248
Cdd:PRK07084 150 AGVEDEV----SAEHHTYTQPEEVE---DFVKKTGVDSLAISIGTSHGAYKfkPG--QCPPPLRFDILEEIEKRipgfpi 220

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 522821568 249 --RKTGAKPVDFVF----HGGS-----GSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDK 303
Cdd:PRK07084 221 vlHGSSSVPQEYVKtineYGGKlkdaiGIPEEQLRKAAKSAVCKINIDSDGRLAMTAAIRKVFDEK 286
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 41-344 2.64e-25

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 103.43  E-value: 2.64e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  41 TVAALQAAREAKSPVIIQFSNGGAHFFAGKFLdnkgekaaiagaiaGAHYVRNLAEAYG--VPVVLHTDHaakkllpwvd 118
Cdd:PRK07315  31 TQAILRAAEAKKAPVLIQTSMGAAKYMGGYKV--------------CKNLIENLVESMGitVPVAIHLDH---------- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 119 GMLEHGKKFFEKNgeplFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGVTGGEEDGVDNSG----IDNAKly 194
Cdd:PRK07315  87 GHYEDALECIEVG----YTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGelapIEDAK-- 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 195 tqpAEVLAAYDALkpignftvAASFGNTHGVYkPGNVQlrppilknSQDAIQKERKTGAKP-VDFVFHGGSGSSPEEIRE 273
Cdd:PRK07315 161 ---AMVETGIDFL--------AAGIGNIHGPY-PENWE--------GLDLDHLEKLTEAVPgFPIVLHGGSGIPDDQIQE 220

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 522821568 274 AVSYGVIKMNIDTDTQWAFTQPIKKYMDDKGAylksqlgNPEGEDKpnKKYIDPRGWLHLGEKGLAARLVE 344
Cdd:PRK07315 221 AIKLGVAKVNVNTECQIAFANATRKFARDYEA-------NEAEYDK--KKLFDPRKFLAPGVKAIQASVEE 282
PRK08610 PRK08610
fructose-bisphosphate aldolase; Reviewed
 41-306 2.17e-24

fructose-bisphosphate aldolase; Reviewed


Pssm-ID: 181501  Cd Length: 286  Bit Score: 100.83  E-value: 2.17e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  41 TVAALQAAREAKSPVIIQFSNGGAHFFAGKFLDNKgekaaiagaiagahYVRNLAEAYG--VPVVLHTDHAAKkllpwvd 118
Cdd:PRK08610  31 TQAILEASQEENAPVILGVSEGAARYMSGFYTVVK--------------MVEGLMHDLNitIPVAIHLDHGSS------- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 119 gmlehgkkfFEKNGEPL---FSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGVTGGEEDGVDNSGIdnakLYT 195
Cdd:PRK08610  90 ---------FEKCKEAIdagFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGI----IYA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 196 QPAEvlaAYDALKPIGNFTVAASFGNTHGVYKpGNVQLrppilknsqdAIQKERKTGAKP-VDFVFHGGSGSSPEEIREA 274
Cdd:PRK08610 157 DPKE---CQELVEKTGIDALAPALGSVHGPYK-GEPKL----------GFKEMEEIGLSTgLPLVLHGGTGIPTKDIQKA 222

                        250       260       270
                 ....*....|....*....|....*....|...
gi 522821568 275 VSYGVIKMNIDTDTQWAFTQPIKKYMD-DKGAY 306
Cdd:PRK08610 223 IPFGTAKINVNTENQIASAKAVRDVLNnDKEVY 255
gatY PRK09195
tagatose-bisphosphate aldolase; Reviewed
 29-327 3.19e-24

tagatose-bisphosphate aldolase; Reviewed


Pssm-ID: 181690  Cd Length: 284  Bit Score: 100.20  E-value: 3.19e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  29 ALPAVNVIGSHSTVAALQAAREAKSPVIIQ-----FSNGGAHFFAgkfldnkgekaaiagaiagaHYVRNLAEAYGVPVV 103
Cdd:PRK09195  19 AVPAFNIHNLETMQVVVETAAELHSPVIIAgtpgtFSYAGTEYLL--------------------AIVSAAAKQYHHPLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 104 LHTDHAAKklLPWVDGMLEHGKKffekngeplfsSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGVTGGEEDGV 183
Cdd:PRK09195  79 LHLDHHEK--FDDIAQKVRSGVR-----------SVMIDGSHLPFAQNISLVKEVVDFCHRFDVSVEAELGRLGGQEDDL 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 184 DNSGIDnaKLYTQPaevLAAYDALKPIGNFTVAASFGNTHGVYKpgnvqlRPPILKNSQDAIQKERKTgakpVDFVFHGG 263
Cdd:PRK09195 146 QVDEAD--ALYTDP---AQAREFVEATGIDSLAVAIGTAHGMYK------GEPKLDFDRLENIRQWVN----IPLVLHGA 210

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 522821568 264 SGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDkgaylksqlgNPEGEDKpnKKYIDP 327
Cdd:PRK09195 211 SGLPTKDIQQTIKLGICKVNVATELKIAFSQALKNYLTE----------HPEANDP--RHYLQP 262
PRK06806 PRK06806
class II aldolase;
95-306 4.61e-23

class II aldolase;


Pssm-ID: 180705  Cd Length: 281  Bit Score: 97.13  E-value: 4.61e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  95 AEAYGVPVVLHTDHAakKLLPWVDGMLEHGkkffekngeplFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELG 174
Cdd:PRK06806  70 AKQAKVPVAVHFDHG--MTFEKIKEALEIG-----------FTSVMFDGSHLPLEENIQKTKEIVELAKQYGATVEAEIG 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 175 VTGGEEDGVDNSGI-----DNAKLYTQPAEVlaayDALkpignftvAASFGNTHGVYKpGNVQLRPPILKNSQDAIqker 249
Cdd:PRK06806 137 RVGGSEDGSEDIEMlltstTEAKRFAEETDV----DAL--------AVAIGNAHGMYN-GDPNLRFDRLQEINDVV---- 199

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 522821568 250 ktgakPVDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDKGAY 306
Cdd:PRK06806 200 -----HIPLVLHGGSGISPEDFKKCIQHGIRKINVATATFNSVITAVNNLVLNTPYS 251
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
29-286 2.87e-22

ketose 1,6-bisphosphate aldolase;


Pssm-ID: 180701  Cd Length: 286  Bit Score: 94.82  E-value: 2.87e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  29 ALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNggAHFfagKFLDnkgekaaiagAIAGAHYVRNLAEAYGVPVVLHTDH 108
Cdd:PRK06801  19 ALGAFNVLDSHFLRALFAAAKQERSPFIINIAE--VHF---KYIS----------LESLVEAVKFEAARHDIPVVLNLDH 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 109 AAKklLPWVDGMLEHGkkffekngeplFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGVTGGEEDGVDNSGI 188
Cdd:PRK06801  84 GLH--FEAVVRALRLG-----------FSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGEA 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 189 DNAKlYTQPAEvlaAYDALKPIGNFTVAASFGNTHGVYKpGNVQLRPPILknsqDAIQKErkTGakpVDFVFHGGSGSSP 268
Cdd:PRK06801 151 DSAK-FTDPQL---ARDFVDRTGIDALAVAIGNAHGKYK-GEPKLDFARL----AAIHQQ--TG---LPLVLHGGSGISD 216

                        250
                 ....*....|....*...
gi 522821568 269 EEIREAVSYGVIKMNIDT 286
Cdd:PRK06801 217 ADFRRAIELGIHKINFYT 234
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
29-327 4.76e-22

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 94.37  E-value: 4.76e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  29 ALPAVNVIGSHSTVAALQAAREAKSPVIIQfSNGGAHFFAGkfLDNkgekaaiagaiaGAHYVRNLAEAYGVPVVLHTDH 108
Cdd:PRK12737  19 AVPAFNIHNLETLQVVVETAAELRSPVILA-GTPGTFSYAG--TDY------------IVAIAEVAARKYNIPLALHLDH 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 109 ------AAKKLlpwvdgmlEHGkkffekngeplFSSHMLDLSEEPLHENLEI-------CQKYLrqmaaikMTLEIELGV 175
Cdd:PRK12737  84 hedlddIKKKV--------RAG-----------IRSVMIDGSHLSFEENIAIvkevvefCHRYD-------ASVEAELGR 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 176 TGGEEDGVDnsgIDNAK-LYTQPAevlAAYDALKPIGNFTVAASFGNTHGVYKpGNVQLRPPILKNSQDAIQkerktgak 254
Cdd:PRK12737 138 LGGQEDDLV---VDEKDaMYTNPD---AAAEFVERTGIDSLAVAIGTAHGLYK-GEPKLDFERLAEIREKVS-------- 202

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 522821568 255 pVDFVFHGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDkgaylksqlgNPEGEDKpnKKYIDP 327
Cdd:PRK12737 203 -IPLVLHGASGVPDEDVKKAISLGICKVNVATELKIAFSDAVKKYFYE----------NPKANDP--RKYMTP 262
PRK09196 PRK09196
fructose-bisphosphate aldolase class II;
30-331 1.34e-21

fructose-bisphosphate aldolase class II;


Pssm-ID: 181691  Cd Length: 347  Bit Score: 94.25  E-value: 1.34e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  30 LPAVNVIGSHSTVAALQAAREAKSPVIIQFSnGGAHFFAG-KFLdnkgekaaiagaiagAHYVRNLAEAY-GVPVVLHTD 107
Cdd:PRK09196  20 VPAFNVNNLEQVQAIMEAADETDSPVILQAS-AGARKYAGePFL---------------RHLILAAVEEYpHIPVVMHQD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 108 HAAKkllPWV-DGMLEHGkkffekngeplFSSHMLDLSeepLHE----------NLEICQKYLRQMAAIKMTLEIELGV- 175
Cdd:PRK09196  84 HGNS---PATcQRAIQLG-----------FTSVMMDGS---LKAdgktpasyeyNVDVTRKVVEMAHACGVSVEGELGCl 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 176 ------TGGEEDGVDNSG-IDNAKLYTQPAEvlaAYDALKPIGNFTVAASFGNTHGVYKpgnvQLRPP---ILknsqdAI 245
Cdd:PRK09196 147 gsletgMGGEEDGHGAEGkLSHDQLLTDPEE---AADFVKKTQVDALAIAIGTSHGAYK----FTRKPtgdVL-----AI 214

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 246 QKERKTGAK-P-VDFVFHgGSGSSP----------------------EEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMD 301
Cdd:PRK09196 215 DRIKEIHARlPnTHLVMH-GSSSVPqelldiineyggdmpetygvpvEEIQEGIKHGVRKVNIDTDLRLAMTGAIRRFLA 293

                        330       340       350
                 ....*....|....*....|....*....|
gi 522821568 302 DkgaylksqlgnpegedkpNKKYIDPRGWL 331
Cdd:PRK09196 294 E------------------NPSEFDPRKYL 305
PRK13399 PRK13399
fructose-bisphosphate aldolase class II;
15-303 5.45e-20

fructose-bisphosphate aldolase class II;


Pssm-ID: 184029  Cd Length: 347  Bit Score: 89.45  E-value: 5.45e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  15 ALQELFEYMKSVECALPAVNVIGSHSTVAALQAAREAKSPVIIQFSnGGAHFFAGK-FLdnkgekaaiagaiagAHYVRN 93
Cdd:PRK13399   5 TLRQLLDHAAENGYGVPAFNVNNMEQILAIMEAAEATDSPVILQAS-RGARKYAGDaML---------------RHMVLA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  94 LAEAY-GVPVVLHTDHAAKkllPWV-DGMLEHGkkffekngeplFSSHMLDLSEEPLHE-------NLEICQKYLRQMAA 164
Cdd:PRK13399  69 AAEMYpDIPICLHQDHGNS---PATcQSAIRSG-----------FTSVMMDGSLLADGKtpasydyNVDVTRRVTEMAHA 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 165 IKMTLEIELGV-------TGGEEDGVDNSG-IDNAKLYTQPAEvlaAYDALKPIGNFTVAASFGNTHGVYKPGnvqlRPP 236
Cdd:PRK13399 135 VGVSVEGELGClgsletgEAGEEDGVGAEGkLSHDQMLTDPDQ---AVDFVQRTGVDALAIAIGTSHGAYKFT----RKP 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 237 ---ILknsqdAIQKERKTGAKPVD--FVFHGGS---------------------GSSPEEIREAVSYGVIKMNIDTDTQW 290
Cdd:PRK13399 208 dgdIL-----AIDRIEEIHARLPNthLVMHGSSsvpqelqeiinayggkmketyGVPVEEIQRGIKHGVRKVNIDTDIRL 282

                        330
                 ....*....|...
gi 522821568 291 AFTQPIKKYMDDK 303
Cdd:PRK13399 283 AMTGAIRKVLAEH 295
PLN02858 PLN02858
fructose-bisphosphate aldolase
 29-298 9.57e-16

fructose-bisphosphate aldolase


Pssm-ID: 215463 [Multi-domain]  Cd Length: 1378  Bit Score: 78.74  E-value: 9.57e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568   29 ALPAVNVIGSHSTVAALQAAREAKSPVIIQ-----FSNGGAHFFAGKFLDnkgekaaiagaiagahyvrnlAEAYGVPVV 103
Cdd:PLN02858 1115 AVGAFNVYNLEGIEAVVAAAEAEKSPAILQvhpgaLKQGGIPLVSCCIAA---------------------AEQASVPIT 1173

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  104 LHTDHAAKK--LLPwvdgMLEHGkkffekngeplFSSHMLDLSEEPLHENLEIcQKYLRQMAAIK-MTLEIELGVTGGEE 180
Cdd:PLN02858 1174 VHFDHGTSKheLLE----ALELG-----------FDSVMVDGSHLSFTENISY-TKSISSLAHSKgLMVEAELGRLSGTE 1237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  181 DGVDNSGIDnaklyTQPAEVLAAYDALKPIGNFTVAASFGNTHGVYKPGNVQLRPPILKNSQDAIQKerktgaKPVDFVF 260
Cdd:PLN02858 1238 DGLTVEEYE-----AKLTDVDQAKEFIDETGIDALAVCIGNVHGKYPASGPNLRLDLLKELRALSSK------KGVLLVL 1306

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 522821568  261 HGGSGSSPEEIREAVSYGVIKMNIDTDTQWAFTQPIKK 298
Cdd:PLN02858 1307 HGASGLPESLIKECIENGVRKFNVNTEVRTAYMEALSS 1344
kbaY PRK12738
tagatose-bisphosphate aldolase subunit KbaY;
29-334 1.42e-15

tagatose-bisphosphate aldolase subunit KbaY;


Pssm-ID: 183711  Cd Length: 286  Bit Score: 76.23  E-value: 1.42e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  29 ALPAVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAgkfldnkgekaaiagAIAGAHYVRNLAEAYGVPVVLHTDH 108
Cdd:PRK12738  19 AVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIA---------------LEEIYALCSAYSTTYNMPLALHLDH 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 109 aaKKLLPWVDGMLEHGKKffekngeplfsSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGVTGGEEDgvDNSGI 188
Cdd:PRK12738  84 --HESLDDIRRKVHAGVR-----------SAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVED--DMSVD 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 189 DNAKLYTQPAEvlaAYDALKPIGNFTVAASFGNTHGVYKPgnvqlRPPIlknSQDAIQKERKTGAKPVdfVFHGGSGSSP 268
Cdd:PRK12738 149 AESAFLTDPQE---AKRFVELTGVDSLAVAIGTAHGLYSK-----TPKI---DFQRLAEIREVVDVPL--VLHGASDVPD 215

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 522821568 269 EEIREAVSYGVIKMNIDTDTQWAFTQPIKKYMDDkgaylksqlgNPEGEdkpnkkyiDPRGWLHLG 334
Cdd:PRK12738 216 EFVRRTIELGVTKVNVATELKIAFAGAVKAWFAE----------NPQGN--------DPRYYMRVG 263
PRK05835 PRK05835
class II fructose-1,6-bisphosphate aldolase;
32-354 2.06e-14

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180280 [Multi-domain]  Cd Length: 307  Bit Score: 73.08  E-value: 2.06e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568  32 AVNVIGSHSTVAALQAAREAKSPVIIQFSNGGAHFFAgkfldnkgekaaiagAIAGAHYVRNLAEAY-GVPVVLHTDHAA 110
Cdd:PRK05835  21 AFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMG---------------IDMAVGMVKIMCERYpHIPVALHLDHGT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 111 KkllpwvdgmLEHGKKFFEKNgeplFSSHMLDLSEEPLHENLEICQKYLRQMAAIKMTLEIELGVTGGEEDGVDNSGIDN 190
Cdd:PRK05835  86 T---------FESCEKAVKAG----FTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISVDEKDA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 191 AKLYTQPAEVLaaydaLKPIGNFTVAASFGNTHGVYK-PGNVQLRPPILKnsqdaiQKERKTGakpVDFVFHGGSgSSPE 269
Cdd:PRK05835 153 VLVNPKEAEQF-----VKESQVDYLAPAIGTSHGAFKfKGEPKLDFERLQ------EVKRLTN---IPLVLHGAS-AIPD 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 522821568 270 EIREA----------------------VSYGVIKMNIDTDTQWAFTQPIKKYMDDkgaylksqlgnpegedkpNKKYIDP 327
Cdd:PRK05835 218 DVRKSyldaggdlkgskgvpfeflqesVKGGINKVNTDTDLRIAFIAEVRKVANE------------------DKSQFDL 279

                        330       340
                 ....*....|....*....|....*..
gi 522821568 328 RGWLHLGEKGLAARLVEAFKDLNSFDK 354
Cdd:PRK05835 280 RKFFSPAQLALKNVVKERMKLLGSANK 306
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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