|
Name |
Accession |
Description |
Interval |
E-value |
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
1-390 |
0e+00 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 529.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGeQSANIARTALLGAGWPVTV 80
Cdd:COG0183 1 MREVVIVDAVRTPFGRFGGALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLQAG-QGQNPARQAALLAGLPESV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIHGAAFGWMAAQR---------YELTSQGEA 151
Cdd:COG0183 80 PAVTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSRAPMLLPKARWGYRMNAKLVDPminpgltdpYTGLSMGET 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 152 AERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKElsepagVLRQDETIRRDTSREKLSTLKTS 231
Cdd:COG0183 160 AENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDEIVPVEVPDRKGEV------VVDRDEGPRPDTTLEKLAKLKPA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 232 FRPDtGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLF 311
Cdd:COG0183 234 FKKD-GTVTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRKALARAGLTLDDIDLI 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 523666866 312 EVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIERL 390
Cdd:COG0183 313 EINEAFAAQVLAVLRELGLDPDKVNVNGGAIALGHPLGASGARILVTLLHELERRGGRYGLATMCIGGGQGIALIIERV 391
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
5-389 |
0e+00 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 513.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 5 VIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEqSANIARTALLGAGWPVTVAGLT 84
Cdd:cd00751 1 VIVSAVRTPIGRFGGALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAGE-GQNPARQAALLAGLPESVPATT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 85 IDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIHGAAFG---------WMAAQRYELTSQGEAAERM 155
Cdd:cd00751 80 VNRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPYLLPKARRGGRLGlntldgmldDGLTDPFTGLSMGITAENV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 156 ADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKElsepagVLRQDETIRRDTSREKLSTLKTSFRPD 235
Cdd:cd00751 160 AEKYGISREEQDEFALRSHQRAAAAQEAGRFKDEIVPVEVPGRKGPV------VVDRDEGPRPDTTLEKLAKLKPAFKKD 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 236 tGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLFEVNE 315
Cdd:cd00751 234 -GTVTAGNASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKRAGLTLDDIDLIEINE 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 523666866 316 AFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIER 389
Cdd:cd00751 313 AFAAQALACLKELGLDPEKVNVNGGAIALGHPLGASGARIVVTLLHELKRRGGRYGLATMCIGGGQGAAMVIER 386
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
6-388 |
4.05e-158 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 449.76 E-value: 4.05e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 6 IVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQsANIARTALLGAGWPVTVAGLTI 85
Cdd:TIGR01930 1 IVAAARTPIGKFGGSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQ-QNIARQAALLAGLPESVPAYTV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 86 DRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIHGAA---FGWMAAQR-------YELTSQGEAAERM 155
Cdd:TIGR01930 80 NRQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRVPYGVPRSLRWGVkpgNAELEDARlkdltdaNTGLPMGVTAENL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 156 ADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKElsepagVLRQDETIRRDTSREKLSTLKTSFRPD 235
Cdd:TIGR01930 160 AKKYGISREEQDEYALRSHQRAAKAWEEGLFKDEIVPVTVKGRKGPV------TVSSDEGIRPNTTLEKLAKLKPAFDPD 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 236 tGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLFEVNE 315
Cdd:TIGR01930 234 -GTVTAGNSSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKKAGLSISDIDLFEINE 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 523666866 316 AFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIE 388
Cdd:TIGR01930 313 AFAAQVLACIKELGLDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGGRYGLATMCIGGGQGAAVILE 385
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
1-390 |
1.30e-157 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 448.39 E-value: 1.30e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPVTV 80
Cdd:PRK07801 1 MAEAYIVDAVRTPVGKRKGGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVDTIGPQAGNIARTSWLAAGLPEEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNReIHGAAFG----------WMAaqRY--ELTSQ 148
Cdd:PRK07801 81 PGVTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQIPISSAM-TAGEQLGftspfaeskgWLH--RYgdQEVSQ 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 149 GEAAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVvveelrekelsepaGVLRQDETIRrDTSREKLSTL 228
Cdd:PRK07801 158 FRGAELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNEIVPV--------------GGVTVDEGPR-ETSLEKMAGL 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 229 KTSFrpDTGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDI 308
Cdd:PRK07801 223 KPLV--EGGRLTAAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYALEKTGLSIDDI 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 309 DLFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIE 388
Cdd:PRK07801 301 DVVEINEAFAPVVLAWLKETGADPAKVNPNGGAIALGHPLGATGAKLMTTLLHELERTGGRYGLQTMCEGGGTANVTIIE 380
|
..
gi 523666866 389 RL 390
Cdd:PRK07801 381 RL 382
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
1-390 |
6.55e-150 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 429.19 E-value: 6.55e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGeQSANIARTALLGAGWPVTV 80
Cdd:PRK05790 1 MKDVVIVSAARTPIGKFGGALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLQAG-AGQNPARQAALKAGLPVEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVP--MGSNREihGAAFGWMAAQ----------RYELTSQ 148
Cdd:PRK05790 80 PALTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQAPhvLPGSRW--GQKMGDVELVdtmihdgltdAFNGYHM 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 149 GEAAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKELsepagVLRQDETIRRDTSREKLSTL 228
Cdd:PRK05790 158 GITAENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDEIVPVTIKQRKGDPV-----VVDTDEHPRPDTTAESLAKL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 229 KTSFRPDtGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDI 308
Cdd:PRK05790 233 RPAFDKD-GTVTAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVPAIRKALEKAGWSLADL 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 309 DLFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIE 388
Cdd:PRK05790 312 DLIEINEAFAAQALAVEKELGLDPEKVNVNGGAIALGHPIGASGARILVTLLHEMKRRGAKKGLATLCIGGGQGVALIVE 391
|
..
gi 523666866 389 RL 390
Cdd:PRK05790 392 RP 393
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
1-390 |
3.96e-146 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 420.06 E-value: 3.96e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFR--GSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPV 78
Cdd:PRK08242 1 MTEAYIYDAVRTPRGKGKkdGSLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVTPVGDQGADIARTAVLAAGLPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 79 TVAGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNreihGAAFGW--MAAQRYELTSQGEAAERMA 156
Cdd:PRK08242 81 TVPGVQINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMSRVPMGSD----GGAWAMdpSTNFPTYFVPQGISADLIA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 157 DKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVvveelrekelSEPAG--VLRQDETIRRDTSREKLSTLKTSFR- 233
Cdd:PRK08242 157 TKYGFSREDVDAYAVESQQRAAAAWAEGYFAKSVVPV----------KDQNGltILDHDEHMRPGTTMESLAKLKPSFAm 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 234 ---------------PDTGRI----TAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAAT 294
Cdd:PRK08242 227 mgemggfdavalqkyPEVERInhvhHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDPTIMLTGPVPAT 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 295 QKVLAKAGLSINDIDLFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQA 374
Cdd:PRK08242 307 RKALAKAGLTVDDIDLFELNEAFASVVLRFMQALDIPHDKVNVNGGAIAMGHPLGATGAMILGTVLDELERRGKRTALIT 386
|
410
....*....|....*.
gi 523666866 375 ICCAGGMGTATIIERL 390
Cdd:PRK08242 387 LCVGGGMGIATIIERV 402
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
1-390 |
8.33e-139 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 401.02 E-value: 8.33e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPVTV 80
Cdd:PRK07850 1 MGNPVIVEAVRTPIGKRNGWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQVIGGCVTQAGEQSNNITRTAWLHAGLPYHV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREiHGAAFGWMAAQRYELTSQGEAAERMADKWA 160
Cdd:PRK07850 81 GATTIDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMSRVPLGANAG-PGRGLPRPDSWDIDMPNQFEAAERIAKRRG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 161 LSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKelSEPAGVLR---QDETIRrDTSREKLSTLKTSFrpDTG 237
Cdd:PRK07850 160 ITREDVDAFGLRSQRRAAQAWAEGRFDREISPVQAPVLDEE--GQPTGETRlvtRDQGLR-DTTMEGLAGLKPVL--EGG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 238 RITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLFEVNEAF 317
Cdd:PRK07850 235 IHTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLEKAGMKIGDIDLVEINEAF 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 523666866 318 ASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIERL 390
Cdd:PRK07850 315 ASVVLSWAQVHEPDMDKVNVNGGAIALGHPVGSTGARLITTALHELERTDKSTALITMCAGGALSTGTIIERI 387
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
1-390 |
1.47e-134 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 390.24 E-value: 1.47e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPVTV 80
Cdd:PRK06504 1 MAEAYIVAAARTAGGRKGGRLAGWHPADLAAQVLDALVDRSGADPALIEDVIMGCVSQVGEQATNVARNAVLASKLPESV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIHG-AAFGWMAAQRYE------LTSQGEAAE 153
Cdd:PRK06504 81 PGTSIDRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTRVPMGSPSTLPAkNGLGHYKSPGMEerypgiQFSQFTGAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 154 RMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVvveelrEKELSEPAGVLRQ-DETIRRDTSREKLSTLKTSf 232
Cdd:PRK06504 161 MMAKKYGLSKDQLDEFALQSHQRAIAATQAGKFKAEIVPL------EITRADGSGEMHTvDEGIRFDATLEGIAGVKLI- 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 233 rPDTGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLFE 312
Cdd:PRK06504 234 -AEGGRLTAATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPVIMLEAPLPATERALKKAGMKIDDIDLYE 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 523666866 313 VNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIERL 390
Cdd:PRK06504 313 VNEAFASVPLAWLKATGADPERLNVNGGAIALGHPLGASGTKLMTTLVHALKQRGKRYGLQTMCEGGGMANVTIVERL 390
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
1-390 |
1.62e-128 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 375.45 E-value: 1.62e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLER-VDVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPVT 79
Cdd:PRK09050 1 MTEAFICDAIRTPIGRYGGALSSVRADDLGAVPLKALMARnPGVDWEAVDDVIYGCANQAGEDNRNVARMSALLAGLPVS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 80 VAGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVP--MGS-------NREIHGAAFGW------MAAQrYE 144
Cdd:PRK09050 81 VPGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRAPfvMGKadsafsrQAEIFDTTIGWrfvnplMKAQ-YG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 145 LTSQGEAAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELRekelSEPAgVLRQDETIRRDTSREK 224
Cdd:PRK09050 160 VDSMPETAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEEIVPVTIPQKK----GDPV-VVDRDEHPRPETTLEA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 225 LSTLKTSFRPDtGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLS 304
Cdd:PRK09050 235 LAKLKPVFRPD-GTVTAGNASGVNDGAAALLLASEAAAKKHGLTPRARILGMATAGVEPRIMGIGPAPATRKLLARLGLT 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 305 INDIDLFEVNEAFASVPLAWMQETGVPH--SKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMG 382
Cdd:PRK09050 314 IDQFDVIELNEAFAAQGLAVLRQLGLADddARVNPNGGAIALGHPLGMSGARLVLTALHQLERTGGRYALCTMCIGVGQG 393
|
....*...
gi 523666866 383 TATIIERL 390
Cdd:PRK09050 394 IALAIERV 401
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
1-390 |
1.03e-120 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 355.04 E-value: 1.03e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFR-GSLAGVRADHLGSLVISRLLER-VDVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPV 78
Cdd:PRK08947 1 MEDVVIVDAIRTPMGRSKgGAFRNVRAEDLSAHLMRSLLARnPALDPAEIDDIIWGCVQQTLEQGFNIARNAALLAGIPH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 79 TVAGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMgsnreIHGAAFGWMAAQRYELTS--QGEAAERMA 156
Cdd:PRK08947 81 SVPAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHVPM-----NHGVDFHPGLSKNVAKAAgmMGLTAEMLG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 157 DKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVvveelrekELSEPAGVLR---QDETIRRDTSREKLSTLKTSFR 233
Cdd:PRK08947 156 KMHGISREQQDAFAARSHQRAWAATQEGRFKNEIIPT--------EGHDADGVLKlfdYDEVIRPETTVEALAALRPAFD 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 234 PDTGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLFEV 313
Cdd:PRK08947 228 PVNGTVTAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGLSISDIDVFEL 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 314 NEAFASVPLAWMQETGVPHS---KLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIERL 390
Cdd:PRK08947 308 NEAFAAQSLPCLKDLGLLDKmdeKVNLNGGAIALGHPLGCSGARISTTLLNLMERKDAQFGLATMCIGLGQGIATVFERV 387
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
1-389 |
1.69e-112 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 334.65 E-value: 1.69e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSAnIARTALLGAGWPVTV 80
Cdd:PRK06205 1 MRDAVICEPVRTPVGRFGGAFKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYPNGEAPA-IGRVAALDAGLPVTV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIHGAAFGWMAAQ----RYELTSQG------- 149
Cdd:PRK06205 80 PGMQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSNVEFYTTDMRWGVRGGGVQLHdrlaRGRETAGGrrfpvpg 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 150 ---EAAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELRekelSEPAgVLRQDETIRRDTSREKLS 226
Cdd:PRK06205 160 gmiETAENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDEIVPVTVPQRK----GDPT-VVDRDEHPRADTTLESLA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 227 TLKT---SFRPDtGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGL 303
Cdd:PRK06205 235 KLRPimgKQDPE-ATVTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGPVPATEKALARAGL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 304 SINDIDLFEVNEAFASVPLAWMQETGVP---HSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGG 380
Cdd:PRK06205 314 TLDDIDLIELNEAFAAQVLAVLKEWGFGaddEERLNVNGSGISLGHPVGATGGRILATLLRELQRRQARYGLETMCIGGG 393
|
....*....
gi 523666866 381 MGTATIIER 389
Cdd:PRK06205 394 QGLAAVFER 402
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
1-389 |
1.15e-111 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 332.07 E-value: 1.15e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGS------LAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSANIARTALLGA 74
Cdd:PRK06445 1 LEDVYLVDFARTAFSRFRPKdpqkdvFNNIRPEELAAMLINRLIEKTGIKPEEIDDIITGCALQVGENWLYGGRHPIFLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 75 GWPVTVAGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNR--EIHGAAFGWMAAQRYELT---SQG 149
Cdd:PRK06445 81 RLPYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTRTPMGDNPhiEPNPKLLTDPKYIEYDLTtgyVMG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 150 EAAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKElsepagVLRQDETIRRDTSREKLSTLK 229
Cdd:PRK06445 161 LTAEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKDEILPIEVEVEGKKK------VVDVDQSVRPDTSLEKLAKLP 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 230 TSFRPDtGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDID 309
Cdd:PRK06445 235 PAFKPD-GVITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKGPVPASKKALEKAGLSVKDID 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 310 LFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIER 389
Cdd:PRK06445 314 LWEINEAFAVVVLYAIKELGLDPETVNIKGGAIAIGHPLGATGARIVGTLARQLQIKGKDYGVATLCVGGGQGGAVVLER 393
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
1-390 |
4.04e-111 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 330.77 E-value: 4.04e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPVTV 80
Cdd:PRK09051 2 MREVVVVSGVRTAIGTFGGSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIPTEPRDMYLSRVAAINAGVPQET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIHGAAFGWMAAQRYELTS---------QGEA 151
Cdd:PRK09051 82 PAFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRAPYLLPAARWGARMGDAKLVDMMVGAlhdpfgtihMGVT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 152 AERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEElREKELsepagVLRQDETIRRDTSREKLSTLKTS 231
Cdd:PRK09051 162 AENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDQIVPVEIKT-RKGEV-----VFDTDEHVRADTTLEDLAKLKPV 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 232 FRPDTGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLF 311
Cdd:PRK09051 236 FKKENGTVTAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQKALERAGLTVADLDVI 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 523666866 312 EVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIERL 390
Cdd:PRK09051 316 EANEAFAAQACAVTRELGLDPAKVNPNGSGISLGHPVGATGAIITVKALYELQRIGGRYALVTMCIGGGQGIAAIFERL 394
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
1-388 |
8.47e-110 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 327.44 E-value: 8.47e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGeQSANIARTALLGAGWPVTV 80
Cdd:PRK08235 1 MSKTVIVSAARTPFGKFGGSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGG-QGQIPSRQAARAAGIPWEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVP-----------MGSNREIHGAAFG--WMAAQRYELTS 147
Cdd:PRK08235 80 QTETVNKVCASGLRAVTLADQIIRAGDASVIVAGGMESMSNAPyilpgarwgyrMGDNEVIDLMVADglTCAFSGVHMGV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 148 QGEAAermADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKELsepagVLRQDETIRRDTSREKLST 227
Cdd:PRK08235 160 YGGEV---AKELGISREAQDEWAYRSHQRAVSAHEEGRFEEEIVPVTIPQRKGDPI-----VVAKDEAPRKDTTIEKLAK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 228 LKTSFRPDtGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSIND 307
Cdd:PRK08235 232 LKPVFDKT-GTITAGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAINALLEKTGKTVED 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 308 IDLFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATII 387
Cdd:PRK08235 311 IDLFEINEAFAAVALASTEIAGIDPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRGGGIGIAAICSGGGQGDAVLI 390
|
.
gi 523666866 388 E 388
Cdd:PRK08235 391 E 391
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
1-390 |
3.98e-108 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 322.86 E-value: 3.98e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKF-RGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPVT 79
Cdd:PRK07661 1 MREAVIVAGARTPVGKAkKGSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMPEAEQGLNMARNIGALAGLPYT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 80 VAGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIHGAAFGWMAAQRYelTSQGEAAERMADKW 159
Cdd:PRK07661 81 VPAITINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSLVPMMGHVVRPNPRLVEAAPEYY--MGMGHTAEQVAVKY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 160 ALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELR---EKELSEPAGVLRQDETIRRDTSREKLSTLKTSFRPDt 236
Cdd:PRK07661 159 GISREDQDAFAVRSHQRAAKALAEGKFADEIVPVDVTLRTvgeNNKLQEETITFSQDEGVRADTTLEILGKLRPAFNVK- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 237 GRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLFEVNEA 316
Cdd:PRK07661 238 GSVTAGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAIPKALKLAGLELSDIGLFELNEA 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 523666866 317 FASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIERL 390
Cdd:PRK07661 318 FASQSIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQFGIVTMCIGGGMGAAGVFELL 391
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
1-390 |
5.69e-108 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 322.72 E-value: 5.69e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKF-RGSLAGVRADHLGSLVISRLLERV-DVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPV 78
Cdd:PRK09052 5 LQDAYIVAATRTPVGKApRGMFKNTRPDDLLAHVLRSAVAQVpGLDPKLIEDAIVGCAMPEAEQGLNVARIGALLAGLPN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 79 TVAGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNR-----------EIHGAAFGwmaaqryelts 147
Cdd:PRK09052 85 SVGGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSMVPMMGNKpsmspaifardENVGIAYG----------- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 148 QGEAAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEE----LREKELSEPAGVLRQDETIRRDTSRE 223
Cdd:PRK09052 154 MGLTAEKVAEQWKVSREDQDAFALESHQKAIAAQQAGEFKDEITPYEITErfpdLATGEVDVKTRTVDLDEGPRADTSLE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 224 KLSTLKTSFRPdTGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGL 303
Cdd:PRK09052 234 GLAKLKPVFAN-KGSVTAGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPIEAIPAALKQAGL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 304 SINDIDLFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGT 383
Cdd:PRK09052 313 KQDDLDWIELNEAFAAQSLAVIRDLGLDPSKVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNLKYGMVTMCVGTGMGA 392
|
....*..
gi 523666866 384 ATIIERL 390
Cdd:PRK09052 393 AGIFERL 399
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
2-391 |
4.76e-107 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 320.50 E-value: 4.76e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 2 KDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTqigeqSANI----ARTALLGAGWP 77
Cdd:PLN02644 1 RDVCIVGVARTPIGGFLGSLSSLSATELGSIAIQAALERAGVDPALVQEVFFGNVL-----SANLgqapARQAALGAGLP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 78 VTVAGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIHGAAFG-------------WMAaqrYE 144
Cdd:PLN02644 76 PSTICTTVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSNAPKYLPEARKGSRLGhdtvvdgmlkdglWDV---YN 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 145 LTSQGEAAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKelsePAGVLRQDETIRRdTSREK 224
Cdd:PLN02644 153 DFGMGVCAELCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWEIVPVEVPGGRGR----PSVIVDKDEGLGK-FDPAK 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 225 LSTLKTSFRPDTGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLS 304
Cdd:PLN02644 228 LRKLRPSFKEDGGSVTAGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPALAIPKALKHAGLE 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 305 INDIDLFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTA 384
Cdd:PLN02644 308 ASQVDYYEINEAFSVVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGARILVTLLGVLRSKNGKYGVAGICNGGGGASA 387
|
....*..
gi 523666866 385 TIIERLD 391
Cdd:PLN02644 388 IVVELMQ 394
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
1-390 |
7.76e-104 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 312.87 E-value: 7.76e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTP--IGKF-RGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWP 77
Cdd:PRK06025 1 MAEAYIIDAVRTPrgIGKVgKGALAHLHPQHLAATVLKALAERNGLNTADVDDIIWSTSSQRGKQGGDLGRMAALDAGYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 78 VTVAGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMS-RVPMGSNREIHGAAFGWMAAQRYEL------TSQGE 150
Cdd:PRK06025 81 IKASGVTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSyTAAMAAEDMAAGKPPLGMGSGNLRLralhpqSHQGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 151 AAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREkelsepagVLRQDETIRRDTSREKLSTLKT 230
Cdd:PRK06025 161 CGDAIATMEGITREALDALGLESQRRAARAIKEGRFDKSLVPVYRDDGSV--------ALDHEEFPRPQTTAEGLAALKP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 231 SFRP------DTGRIT-------------------AGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTL 285
Cdd:PRK06025 233 AFTAiadyplDDKGTTyrglinqkypdleikhvhhAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 286 MLTGPIAATQKVLAKAGLSINDIDLFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELER 365
Cdd:PRK06025 313 MLNAPVPAAKKVLAKAGLTKDDIDLWEINEAFAVVAEKFIRDLDLDRDKVNVNGGAIALGHPIGATGSILIGTVLDELER 392
|
410 420
....*....|....*....|....*
gi 523666866 366 RGGRYGLQAICCAGGMGTATIIERL 390
Cdd:PRK06025 393 RGLKRGLVTMCAAGGMAPAIIIERV 417
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
1-389 |
2.71e-100 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 302.96 E-value: 2.71e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGeQSANIARTALLGAGWPVTV 80
Cdd:PRK05656 1 MQDVVIVAATRTAIGSFQGSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAG-AGQNPARQAAIKAGLPHSV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVP-----------MGSNREIHGAAFG--WMAAQRYELts 147
Cdd:PRK05656 80 PAMTLNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSLAPyvlpgartglrMGHAQLVDSMITDglWDAFNDYHM-- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 148 qGEAAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELRekelSEPAgVLRQDETIRRDTSREKLST 227
Cdd:PRK05656 158 -GITAENLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDEITPILIPQRK----GEPL-AFATDEQPRAGTTAESLAK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 228 LKTSFRPDtGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSIND 307
Cdd:PRK05656 232 LKPAFKKD-GSVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIMGIGPVSATRRCLDKAGWSLAE 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 308 IDLFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATII 387
Cdd:PRK05656 311 LDLIEANEAFAAQSLAVGKELGWDAAKVNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDAKKGLATLCIGGGQGVALAI 390
|
..
gi 523666866 388 ER 389
Cdd:PRK05656 391 ER 392
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
3-391 |
2.57e-98 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 300.14 E-value: 2.57e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 3 DIVIVDAVRTPIGKF-RGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPVTVA 81
Cdd:PLN02287 47 DVVIVAAYRTPICKAkRGGFKDTYPDDLLAPVLKAVVEKTGLNPSEVGDIVVGTVLAPGSQRANECRMAAFYAGFPETVP 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 82 GLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIHGAAFGWMAAQRYeLTSQGEAAERMADKWAL 161
Cdd:PLN02287 127 VRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGVESMTTNPMAWEGGVNPRVESFSQAQDC-LLPMGITSENVAERFGV 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 162 SRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKELSEPAGVLRQDETIRRDTSREKLSTLKTSFRPDtGRITA 241
Cdd:PLN02287 206 TREEQDQAAVESHRKAAAATASGKFKDEIVPVHTKIVDPKTGEEKPIVISVDDGIRPNTTLADLAKLKPVFKKN-GTTTA 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 242 GNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLFEVNEAFASVP 321
Cdd:PLN02287 285 GNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAVGVDPAVMGIGPAVAIPAAVKAAGLELDDIDLFEINEAFASQF 364
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 523666866 322 LAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRG--GRYGLQAICCAGGMGTATIIERLD 391
Cdd:PLN02287 365 VYCCKKLGLDPEKVNVNGGAIALGHPLGATGARCVATLLHEMKRRGkdCRFGVVSMCIGTGMGAAAVFERGD 436
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
1-390 |
1.07e-95 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 291.52 E-value: 1.07e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGK-FRGSLAGVRADHLGSLVISRLLERV-DVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPv 78
Cdd:PRK07851 1 MPEAVIVSTARSPIGRaFKGSLKDMRPDDLAAQMVRAALDKVpALDPTDIDDLMLGCGLPGGEQGFNMARVVAVLLGYD- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 79 TVAGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREI---HGAAFGwMAAQRYELTSQGEA---- 151
Cdd:PRK07851 80 FLPGTTVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVSRFAKGNSDSLpdtKNPLFA-EAQARTAARAEGGAeawh 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 152 ------------------AERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVeelrekelsePAG-VLRQ 212
Cdd:PRK07851 159 dpredgllpdvyiamgqtAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFEREITPVTL----------PDGtVVST 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 213 DETIRRDTSREKLSTLKTSFRPDtGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIA 292
Cdd:PRK07851 229 DDGPRAGTTYEKVSQLKPVFRPD-GTVTAGNACPLNDGAAAVVIMSDTKARELGLTPLARIVSTGVSGLSPEIMGLGPVE 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 293 ATQKVLAKAGLSINDIDLFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGL 372
Cdd:PRK07851 308 ASKQALARAGMSIDDIDLVEINEAFAAQVLPSARELGIDEDKLNVSGGAIALGHPFGMTGARITTTLLNNLQTHDKTFGL 387
|
410
....*....|....*...
gi 523666866 373 QAICCAGGMGTATIIERL 390
Cdd:PRK07851 388 ETMCVGGGQGMAMVLERL 405
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
1-391 |
8.13e-94 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 286.67 E-value: 8.13e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPVTV 80
Cdd:PRK08131 1 MLDAYIYDGLRSPFGRHAGALASVRPDDLAATVIRRLLEKSGFPGDDIEDVILGCTNQAGEDSRNVARNALLLAGLPVTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVP--MGS-----NREIH------GAAF-GWMAAQRYELT 146
Cdd:PRK08131 81 PGQTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRAPfvMGKaesafSRDAKvfdttiGARFpNPKIVAQYGND 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 147 SQGEAAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKelsePAGVLRQDETIRRDTSREKLS 226
Cdd:PRK08131 161 SMPETGDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADEITPIEVPQGRKL----PPKLVAEDEHPRPSSTVEALT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 227 TLKTSFrpDTGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSIN 306
Cdd:PRK08131 237 KLKPLF--EGGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMGIGPVEAIKKALARAGLTLD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 307 DIDLFEVNEAFASVPLAWMQETGVPH--SKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTA 384
Cdd:PRK08131 315 DMDIIEINEAFASQVLGCLKGLGVDFddPRVNPNGGAIAVGHPLGASGARLALTAARELQRRGKRYAVVSLCIGVGQGLA 394
|
....*..
gi 523666866 385 TIIERLD 391
Cdd:PRK08131 395 MVIERVS 401
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
1-390 |
4.00e-91 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 279.35 E-value: 4.00e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGK-FRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSANIARTALLGAGWPVT 79
Cdd:PRK07108 1 MTEAVIVSTARTPLAKsWRGAFNMTHGATLGGHVVQHAVERAKLDPAEVEDVIMGCANPEGATGANIARQIALRAGLPVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 80 VAGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNReiHGAAFGWMAAQRYELT-SQGEAAERMADK 158
Cdd:PRK07108 81 VPGMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESISCVQNEMNR--HMLREGWLVEHKPEIYwSMLQTAENVAKR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 159 WALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVE---------ELREKELSepagvLRQDETIRRDTSREKLSTLK 229
Cdd:PRK07108 159 YGISKERQDEYGVQSQQRAAAAQAAGRFDDEIVPITVTagvadkatgRLFTKEVT-----VSADEGIRPDTTLEGVSKIR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 230 TSFrpDTGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDID 309
Cdd:PRK07108 234 SAL--PGGVITAGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPVFAVPKLLKQAGLKVDDID 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 310 LFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIER 389
Cdd:PRK07108 312 LWELNEAFAVQVLYCRDTLGIPMDRLNVNGGAIAVGHPYGVSGARLTGHALIEGKRRGAKYVVVTMCIGGGQGAAGLFEV 391
|
.
gi 523666866 390 L 390
Cdd:PRK07108 392 L 392
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
1-388 |
6.73e-91 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 278.84 E-value: 6.73e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQiGEQSANIARTALLGAGWPVTV 80
Cdd:PRK06633 2 TKPVYITHAKRTAFGSFMGSLSTTPAPMLAAHLIKDILQNSKIDPALVNEVILGQVIT-GGSGQNPARQTLIHAGIPKEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIhGAAFG---WMAAQRYE-LTS------QGE 150
Cdd:PRK06633 81 PGYTINKVCGSGLKSVALAANSIMTGDNEIVIAGGQENMSLGMHGSYIRA-GAKFGdikMVDLMQYDgLTDvfsgvfMGI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 151 AAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVvveelrEKELSEPAGVLRQDETIRRDTSREKLSTLKT 230
Cdd:PRK06633 160 TAENISKQFNISRQEQDEFALSSHKKAAKAQLAGIFKDEILPI------EVTIKKTTSLFDHDETVRPDTSLEILSKLRP 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 231 SFRPDtGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDL 310
Cdd:PRK06633 234 AFDKN-GVVTAGNASSINDGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPASQKALSKAGWSVNDLEV 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 523666866 311 FEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIE 388
Cdd:PRK06633 313 IEVNEAFAAQSIYVNREMKWDMEKVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAKKGLVTLCIGGGMGMAMCVE 390
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
4-389 |
2.80e-90 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 278.41 E-value: 2.80e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 4 IVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEqSANIARTALLGAGWPVTVAGL 83
Cdd:PRK08963 7 IAIVSGLRTPFAKQATAFHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVQMPE-APNIAREIVLGTGMNVHTDAY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 84 TIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNRE----IHGAAFGWMAAQRYELTSQ----------- 148
Cdd:PRK08963 86 SVSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSVLPIGVSKKlaraLVDLNKARTLGQRLKLFSRlrlrdllpvpp 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 149 -----------GEAAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREkelsepagVLRQDETIR 217
Cdd:PRK08963 166 avaeystglrmGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDEVMTAHVPPYKQ--------PLEEDNNIR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 218 RDTSREKLSTLKTSFRPDTGRITAGNSSQISDGAAALLLMSADTAKKLGLK--ARARVVAFT--TVGSDptlMLTGPIAA 293
Cdd:PRK08963 238 GDSTLEDYAKLRPAFDRKHGTVTAANSTPLTDGAAAVLLMSESRAKALGLTplGYLRSYAFAaiDVWQD---MLLGPAYA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 294 TQKVLAKAGLSINDIDLFEVNEAFASVPLAWMQETG-----------------VPHSKLNVNGGAIALGHPLGASGARLM 356
Cdd:PRK08963 315 TPLALERAGLTLADLTLIDMHEAFAAQTLANLQMFAserfareklgrsqaigeVDMSKFNVLGGSIAYGHPFAATGARMI 394
|
410 420 430
....*....|....*....|....*....|...
gi 523666866 357 TTMLNELERRGGRYGLQAICCAGGMGTATIIER 389
Cdd:PRK08963 395 TQTLHELRRRGGGLGLTTACAAGGLGAAMVLEV 427
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
4-388 |
1.49e-88 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 272.92 E-value: 1.49e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 4 IVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSANiARTALLGAGWPVTVAGL 83
Cdd:PRK06954 9 IVIASAARTPMAAFQGEFASLTAPQLGAAAIAAAVERAGLKPEQIDEVVMGCVLPAGQGQAP-ARQAALGAGLPLSVGCT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 84 TIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPM------GSNREIHGAAFGWMAAQRYELT-----SQGEAA 152
Cdd:PRK06954 88 TVNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESMTNAPYllpkarGGMRMGHGQVLDHMFLDGLEDAydkgrLMGTFA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 153 ERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKElsepagVLRQDETIRRdTSREKLSTLKTSF 232
Cdd:PRK06954 168 EECAGEYGFTREAQDAFAIESLARAKRANEDGSFAWEIAPVTVAGKKGDT------VIDRDEQPFK-ANPEKIPTLKPAF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 233 RPDtGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLFE 312
Cdd:PRK06954 241 SKT-GTVTAANSSSISDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPVGAIRKLFEKNGWRAAEVDLFE 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 523666866 313 VNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIE 388
Cdd:PRK06954 320 INEAFAVVTMAAMKEHGLPHEKVNVNGGACALGHPIGASGARILVTLIGALRARGGKRGVASLCIGGGEATAMGIE 395
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
5-390 |
6.93e-83 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 257.39 E-value: 6.93e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 5 VIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVdvsPTLVDDVIFGNVTQIGeqsANIARTALLGAGWPVTVAGLT 84
Cdd:PRK06690 4 VIVEAKRTPIGKKNGMLKDYEVQQLAAPLLTFLSKGM---EREIDDVILGNVVGPG---GNVARLSALEAGLGLHIPGVT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 85 IDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMgSNReihgAAFgwmAAQRYELTSQGEAAERMADKWALSRD 164
Cdd:PRK06690 78 IDRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSPF-QNR----ARF---SPETIGDPDMGVAAEYVAERYNITRE 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 165 ALDDFAFASHQRAATACDAGYFDNETIPVvveelrekelsepAGVLrqDETIRRDTSREKL-STLKTSFRPDtGRITAGN 243
Cdd:PRK06690 150 MQDEYACLSYKRTLQALEKGYIHEEILSF-------------NGLL--DESIKKEMNYERIiKRTKPAFLHN-GTVTAGN 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 244 SSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLFEVNEAFASVPLA 323
Cdd:PRK06690 214 SCGVNDGACAVLVMEEGQARKLGYKPVLRFVRSAVVGVDPNLPGTGPIFAVNKLLNEMNMKVEDIDYFEINEAFASKVVA 293
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 523666866 324 WMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIERL 390
Cdd:PRK06690 294 CAKELQIPYEKLNVNGGAIALGHPYGASGAMLVTRLFYQAKREDMKYGIATLGIGGGIGLALLFEKV 360
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
1-390 |
1.39e-81 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 256.10 E-value: 1.39e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQsANIARTALLGAGWPVTV 80
Cdd:PRK08170 2 ARPVYIVDGARTPFLKARGGPGPFSASDLAVAAGRALLNRQPFAPDDLDEVILGCAMPSPDE-ANIARVVALRLGCGEKV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIHGAAFGWMAAQ--------------RY--- 143
Cdd:PRK08170 81 PAWTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMSHAPLLFSEKMVRWLAGWYAAKsigqklaalgklrpSYlap 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 144 ------ELT------SQGEAAERMADKWALSRDALDDFAFASHQRAATACDAGYFdNETIPVVVEELRekelsepagVLR 211
Cdd:PRK08170 161 vigllrGLTdpvvglNMGQTAEVLAHRFGITREQMDAYAARSHQRLAAAQAEGRL-KEVVPLFDRDGK---------FYD 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 212 QDETIRRDTSREKLSTLKTSFRPDTGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPI 291
Cdd:PRK08170 231 HDDGVRPDSSMEKLAKLKPFFDRPYGRVTAGNSSQITDGACWLLLASEEAVKKYGLPPLGRIVDSQWAALDPSQMGLGPV 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 292 AATQKVLAKAGLSINDIDLFEVNEAFASVPL----AW------MQETGVPHS-------KLNVNGGAIALGHPLGASGAR 354
Cdd:PRK08170 311 HAATPLLQRHGLTLEDLDLWEINEAFAAQVLaclaAWadeeycREQLGLDGAlgeldreRLNVDGGAIALGHPVGASGAR 390
|
410 420 430
....*....|....*....|....*....|....*.
gi 523666866 355 LMTTMLNELERRGGRYGLQAICCAGGMGTATIIERL 390
Cdd:PRK08170 391 IVLHLLHALKRRGTKRGIAAICIGGGQGGAMLLERV 426
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
1-391 |
2.98e-74 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 236.06 E-value: 2.98e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 1 MKDIVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGeQSANIARTALLGAGWPVTV 80
Cdd:PRK06366 1 MKDVYIVSAKRTAIGKFGRSFSKIKAPQLGGAAIKAVIDDAKLDPALVQEVIMGNVIQAG-VGQNPAGQAAYHAGLPFGV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 81 AGLTIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVP--------------MGSNREIHGAAF--GWMAAQRYE 144
Cdd:PRK06366 80 TKYTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPfllpsdlrwgpkhlLHKNYKIDDAMLvdGLIDAFYFE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 145 ltSQGEAAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVvveelrekelsepaGVLRQDETIRRdTSREK 224
Cdd:PRK06366 160 --HMGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNEIVPF--------------NDLDRDEGIRK-TTMED 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 225 LSTLKTSFRPDtGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLS 304
Cdd:PRK06366 223 LAKLPPAFDKN-GILTAGNSAQLSDGGSALVMASEKAINEYGLKPIARITGYESASLDPLDFVEAPIPATRKLLEKQNKS 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 305 INDIDLFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTA 384
Cdd:PRK06366 302 IDYYDLVEHNEAFSIASIIVRDQLKIDNERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTRHMKTGLATLCHGGGGAHT 381
|
....*..
gi 523666866 385 TIIERLD 391
Cdd:PRK06366 382 LTLEMVE 388
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
4-260 |
3.52e-70 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 221.02 E-value: 3.52e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 4 IVIVDAVRTPIGKFRGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQiGEQSANIARTALLGAGWPVTVAGL 83
Cdd:pfam00108 1 VVIVSAARTPFGSFGGSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQ-AGEGQNPARQAALKAGIPDSAPAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 84 TIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIH-GAAFGwmAAQRYELTS------------QGE 150
Cdd:pfam00108 80 TINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALPTDARsGLKHG--DEKKHDLLIpdgltdafngyhMGL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 151 AAERMADKWALSRDALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKelsepaGVLRQDETIRRDTSREKLSTLKT 230
Cdd:pfam00108 158 TAENVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDEIVPVTVKGRKGK------PTVDKDEGIRPPTTAEPLAKLKP 231
|
250 260 270
....*....|....*....|....*....|
gi 523666866 231 SFRPDtGRITAGNSSQISDGAAALLLMSAD 260
Cdd:pfam00108 232 AFDKE-GTVTAGNASPINDGAAAVLLMSES 260
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
147-389 |
5.24e-55 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 187.03 E-value: 5.24e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 147 SQGEAAERMADKWALSRDALDDFAFASHQRAATACDAGYFDnetipvvveelrekELSEPAGVLRQDETIRRDTSREKLS 226
Cdd:PRK09268 177 SMGEHAAITAKEWGISREAQDELAAASHQNLAAAYDRGFFD--------------DLITPFLGLTRDNNLRPDSSLEKLA 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 227 TLKTSF-RPDTGRITAGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTV------GSDPTLMltGPIAATQKVLA 299
Cdd:PRK09268 243 KLKPVFgKGGRATMTAGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDAETAavdfvhGKEGLLM--APAYAVPRLLA 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 300 KAGLSINDIDLFEVNEAFASVPL----AWMQET-------------GVPHSKLNVNGGAIALGHPLGASGARLMTTMLNE 362
Cdd:PRK09268 321 RNGLTLQDFDFYEIHEAFASQVLatlkAWEDEEycrerlgldaplgSIDRSKLNVNGSSLAAGHPFAATGGRIVATLAKL 400
|
250 260
....*....|....*....|....*..
gi 523666866 363 LERRGGRYGLQAICCAGGMGTATIIER 389
Cdd:PRK09268 401 LAEKGSGRGLISICAAGGQGVTAILER 427
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
267-389 |
7.49e-55 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 176.68 E-value: 7.49e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 267 LKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLFEVNEAFASVPLAWMQETGVPHSKLNVNGGAIALGH 346
Cdd:pfam02803 1 LKPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPEKVNVNGGAIALGH 80
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 523666866 347 PLGASGARLMTTMLNELERRGGRYGLQAICCAGGMGTATIIER 389
Cdd:pfam02803 81 PLGASGARILVTLLHELKRRGGKYGLASLCIGGGQGVAMIIER 123
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
7-388 |
2.68e-45 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 160.74 E-value: 2.68e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 7 VDAVRTPIGKF---RGSLAGVRADHLGSLVISRLLERVDVSPTLVDDVIFGNVTQIGEQSaNIARTALLGAGWPVTVAGL 83
Cdd:cd00826 1 AGAAMTAFGKFggeNGADANDLAHEAGAKAIAAALEPAGVAAGAVEEACLGQVLGAGEGQ-NCAQQAAMHAGGLQEAPAI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 84 TIDRKCGSGEVAVHMAVGAIAAGAADIVVAGGAENMSRVPMGSNREIHgaafgwmaaqryeltsqgeaAERMADKWAlSR 163
Cdd:cd00826 80 GMNNLCGSGLRALALAMQLIAGGDANCILAGGFEKMETSAENNAKEKH--------------------IDVLINKYG-MR 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 164 DALDDFAFASHQRAATACDAGYFDNETIPVVVEELREKELSEpagvlrQDETIR--RDTSREKLSTLKTSFRPDtGRITA 241
Cdd:cd00826 139 ACPDAFALAGQAGAEAAEKDGRFKDEFAKFGVKGRKGDIHSD------ADEYIQfgDEASLDEIAKLRPAFDKE-DFLTA 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 242 GNSSQISDGAAALLLMSADTAKKLGLKARA-------RVVAFTTVGSDPT----LMLTGPIAATQKVLAKAGLSINDIDL 310
Cdd:cd00826 212 GNACGLNDGAAAAILMSEAEAQKHGLQSKAreiqaleMITDMASTFEDKKvikmVGGDGPIEAARKALEKAGLGIGDLDL 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 311 FEVNEAFASVPLAWMQETGV------------------PHSKLNVNGGAIALGHPLGASGARLMTTMLNELERRGG---- 368
Cdd:cd00826 292 IEAHDAFAANACATNEALGLcpegqggalvdrgdntygGKSIINPNGGAIAIGHPIGASGAAICAELCFELKGEAGkrqg 371
|
410 420
....*....|....*....|.
gi 523666866 369 -RYGLQAICCAGGMGTATIIE 388
Cdd:cd00826 372 aGAGLALLCIGGGGGAAMCIE 392
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
33-387 |
3.42e-19 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 88.09 E-value: 3.42e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 33 VISRLLERVDVSPTLVDDVIFGNVTQIGEQS---ANIARTALLGAGWPVTVagltiDRKCGSGEVAVHMAVGAIAAGAAD 109
Cdd:cd00829 23 AARAALDDAGLEPADIDAVVVGNAAGGRFQSfpgALIAEYLGLLGKPATRV-----EAAGASGSAAVRAAAAAIASGLAD 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 110 IVVAGGAENMSRVPMGSNREIHGAAFGWMAAQRYELTSQ----GEAAERMADKWALSRDALDDFAFASHQRAATACDAGY 185
Cdd:cd00829 98 VVLVVGAEKMSDVPTGDEAGGRASDLEWEGPEPPGGLTPpalyALAARRYMHRYGTTREDLAKVAVKNHRNAARNPYAQF 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 186 FDNETipvVVEELREKELSEPagvlrqdetirrdtsreklstlktsfrpdtgrITAGNSSQISDGAAALLLMSADTAKKL 265
Cdd:cd00829 178 RKPIT---VEDVLNSRMIADP--------------------------------LRLLDCCPVSDGAAAVVLASEERAREL 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 266 GLKArARVVAfTTVGSDPTLM--------LTGPIAATQKVLAKAGLSINDIDLFEVNEAFASVPLAWMQETG-------- 329
Cdd:cd00829 223 TDRP-VWILG-VGAASDTPSLserddflsLDAARLAARRAYKMAGITPDDIDVAELYDCFTIAELLALEDLGfcekgegg 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 330 -------------VPHsklNVNGGAIALGHPLGASGARlmttMLNELER--RGGRYGLQAICC-------AGGMGTATII 387
Cdd:cd00829 301 klvregdtaiggdLPV---NTSGGLLSKGHPLGATGLA----QAVEAVRqlRGEAGARQVPGArvglahnIGGTGSAAVV 373
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
241-387 |
6.59e-14 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 70.94 E-value: 6.59e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 241 AGNSSQISDGAAALLLMSADTAKKLGLKARARVVAFTTVGSDPT----LMLTGPIAATQKVLAKAGLSINDIDLFEVNEA 316
Cdd:cd00327 94 GSEEFVFGDGAAAAVVESEEHALRRGAHPQAEIVSTAATFDGASmvpaVSGEGLARAARKALEGAGLTPSDIDYVEAHGT 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 317 FASVPLAWMQETGVPHSK---LNVNGGAIALGHPLGASGARLMTTMLNELE-------RRGGRYGLQAICCAGGMGTATI 386
Cdd:cd00327 174 GTPIGDAVELALGLDPDGvrsPAVSATLIMTGHPLGAAGLAILDELLLMLEhefipptPREPRTVLLLGFGLGGTNAAVV 253
|
.
gi 523666866 387 I 387
Cdd:cd00327 254 L 254
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
245-375 |
1.58e-10 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 62.22 E-value: 1.58e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 245 SQISDGAAALLLMSADTAKKLGLKAR-ARVVAFTTVGS----------DPTLMLTGPIAAtQKVLAKAGLSINDIDLFEV 313
Cdd:PTZ00455 256 SQVSDGGAGLVLASEEGLQKMGLSPNdSRLVEIKSLACasgnlyedppDATRMFTSRAAA-QKALSMAGVKPSDLQVAEV 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 314 NEAFASVPLAWMQETGVP---HSK---------------LNVNGGAIALGHPLGASGARLMTTMLNELERRGGRYGLQAI 375
Cdd:PTZ00455 335 HDCFTIAELLMYEALGIAeygHAKdlirngatalegripVNTGGGLLSFGHPVGATGVKQIMEVYRQMKGQCGEYQMKNI 414
|
|
| PRK07516 |
PRK07516 |
thiolase domain-containing protein; |
245-352 |
2.08e-10 |
|
thiolase domain-containing protein;
Pssm-ID: 181013 [Multi-domain] Cd Length: 389 Bit Score: 61.89 E-value: 2.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 245 SQISDGAAALLLMSADTAKKL----GLKARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLFEVNEAFASV 320
Cdd:PRK07516 213 SLVSDGAAALVLADAETARALqravRFRARAHVNDFLPLSRRDPLAFEGPRRAWQRALAQAGVTLDDLSFVETHDCFTIA 292
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 523666866 321 PL--------------------AWMQETGvphsKLNVN--GGAIALGHPLGASG 352
Cdd:PRK07516 293 ELieyeamglappgqgaraireGWTAKDG----KLPVNpsGGLKAKGHPIGATG 342
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
244-354 |
2.90e-09 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 58.37 E-value: 2.90e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 244 SSQISDGAAALLLMSADTAKKL---GLKARARVVAFTTVG-SDPTLMLT--GPIAATQKVLAKAGLSINDIDLFEVNEAF 317
Cdd:PRK06064 208 CSPITDGAAAVILASEEKAKEYtdtPVWIKASGQASDTIAlHDRKDFTTldAAVVAAEKAYKMAGIEPKDIDVAEVHDCF 287
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 523666866 318 ASVPLAWMQETG---------------------VPhskLNVNGGAIALGHPLGASGAR 354
Cdd:PRK06064 288 TIAEILAYEDLGfakkgeggklaregqtyiggdIP---VNPSGGLKAKGHPVGATGVS 342
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
237-356 |
2.40e-07 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 52.38 E-value: 2.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 237 GRITAGNSSQISDGAAALLLMSADTAKKLGlKAR--ARVVAF--TTVG----------SDPTLMLTGPIAATQKVLAKAG 302
Cdd:PRK06289 212 GRLRRQDCSQVTDGGAGVVLASDAYLRDYA-DARpiPRIKGWghRTAPlgleqkldrsAGDPYVLPHVRQAVLDAYRRAG 290
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 523666866 303 LSINDIDLFEVNEAFASVPLAWMQETGV----------------PHSKLNVN--GGAIALGHPLGASGARLM 356
Cdd:PRK06289 291 VGLDDLDGFEVHDCFTPSEYLAIDHIGLtgpgeswkaiengeiaIGGRLPINpsGGLIGGGHPVGASGVRML 362
|
|
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
248-352 |
6.71e-06 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 47.59 E-value: 6.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 248 SDGAAALLLMSADTAKKLGLKARARVV--AFTT--------------VGSDPTlmltgpIAATQKVLAKAGLSINDIDLF 311
Cdd:PRK08256 214 TCGAAAAIVCSEEFARKHGLDRAVEIVaqAMTTdtpstfdgrsmidlVGYDMT------RAAAQQVYEQAGIGPEDIDVV 287
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 523666866 312 EVNEAFAS------VPLAWMQETGVPhsKL--------------NVNGGAIALGHPLGASG 352
Cdd:PRK08256 288 ELHDCFSAnelltyEALGLCPEGEAE--KFiddgdntyggrwvvNPSGGLLSKGHPLGATG 346
|
|
| PRK05952 |
PRK05952 |
beta-ketoacyl-ACP synthase; |
249-353 |
1.69e-05 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235653 [Multi-domain] Cd Length: 381 Bit Score: 46.58 E-value: 1.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 249 DGAAALLLMSADTAKKLGLKARARVVAFTTV-----GSDPTLMLTGPIAATQKVLAKAGLSINDIDLF-------EVNEA 316
Cdd:PRK05952 210 EGGAILVLESAELAQKRGAKIYGQILGFGLTcdayhMSAPEPDGKSAIAAIQQCLARSGLTPEDIDYIhahgtatRLNDQ 289
|
90 100 110
....*....|....*....|....*....|....*..
gi 523666866 317 FASvplAWMQeTGVPHsKLNVNGGAIALGHPLGASGA 353
Cdd:PRK05952 290 REA---NLIQ-ALFPH-RVAVSSTKGATGHTLGASGA 321
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
243-368 |
1.78e-05 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 46.38 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 243 NSSQISDGAAALLLMSADTAKKLGLKArarVVAFTTVG--SDPTLM--------LTGPIAATQKVLAKAGLSINDIDLFE 312
Cdd:PRK12578 205 DSCPISDGSATAIFASEEKVKELKIDS---PVWITGIGyaNDYAYVarrgewvgFKATQLAARQAYNMAKVTPNDIEVAT 281
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 523666866 313 VNEAFASVPLAWMQETGVPHS----------------KLNVN--GGAIALGHPLGASGARLMTTMLNELERRGG 368
Cdd:PRK12578 282 VHDAFTIAEIMGYEDLGFTEKgkggkfieegqsekggKVGVNlfGGLKAKGHPLGATGLSMIYEITKQLRDEAG 355
|
|
| PRK08257 |
PRK08257 |
acetyl-CoA acetyltransferase; Validated |
249-372 |
2.36e-05 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 236204 [Multi-domain] Cd Length: 498 Bit Score: 46.06 E-value: 2.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 249 DGAAALLLMSADTAKKLGLkARARVVAF--TTVGSDPTLMLTGP--------IAATQKVLAKAGLSINDIDLFEVNEAFA 318
Cdd:PRK08257 244 DQGAAVLLTSVAKARRLGV-PEDRWVYLhgGADAHDPYDILERPdlhrspaiRAAGRRALALAGLGIDDIDAFDLYSCFP 322
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 523666866 319 SVPLAWMQETGVPHSK---LNVNGgaialGHPL-GASGARLMT----TMLNELERRGGRYGL 372
Cdd:PRK08257 323 SAVQVAARELGLDLDDprpLTVTG-----GLPFfGGPGNNYVThaiaEMVERLRANPGRRGL 379
|
|
| PRK06157 |
PRK06157 |
acetyl-CoA acetyltransferase; Validated |
247-369 |
3.07e-05 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 180433 [Multi-domain] Cd Length: 398 Bit Score: 45.79 E-value: 3.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 247 ISDGAAALLLMSADTAKKLGLKARARVVAFT-TVGSDPTLMLTG--------PIAATQKVLAKAGLS--INDIDLFEVNE 315
Cdd:PRK06157 216 VSDGAAAAIVTTPEIARALGKKDPVYVKALQlAVSNGWELQYNGwdgsyfptTRIAARKAYREAGITdpREELSMAEVHD 295
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 523666866 316 AFASVPLAWMQETG---------------------VPhskLNVNGGAIALGHPLGASGARLMTTM-LNELERRGGR 369
Cdd:PRK06157 296 CFSITELVTMEDLGlsergqawrdvldgffdadggLP---CQIDGGLKCFGHPIGASGLRMLYEMyLQLLGRAGER 368
|
|
| elong_cond_enzymes |
cd00828 |
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
248-366 |
9.22e-05 |
|
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP) thioesters as primer substrates, as well as the nature of their active site residues.
Pssm-ID: 238424 [Multi-domain] Cd Length: 407 Bit Score: 44.35 E-value: 9.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 248 SDGAAALLLMSADTAKKLGLKARARvVAFTTVGSDP-----TLMLTGPIAATQKVLAKAGLSINDIDLfeVNEAFASVPL 322
Cdd:cd00828 230 AEGAGVLVLERAELALARGAPIYGR-VAGTASTTDGagrsvPAGGKGIARAIRTALAKAGLSLDDLDV--ISAHGTSTPA 306
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 523666866 323 AWMQETGVPHSKLNVNGGAIAL-------GHPLGASGARLMTTMLNELERR 366
Cdd:cd00828 307 NDVAESRAIAEVAGALGAPLPVtaqkalfGHSKGAAGALQLIGALQSLEHG 357
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
247-353 |
8.89e-04 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 41.23 E-value: 8.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 247 ISDGAAALLLMSADTAKKLGLKARARVVAF--TTVGSDPTLM---LTGPIAATQKVLAKAGLSINDIDLfeVNeafA--- 318
Cdd:COG0304 229 LGEGAGVLVLEELEHAKARGAKIYAEVVGYgaSSDAYHITAPapdGEGAARAMRAALKDAGLSPEDIDY--IN---Ahgt 303
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 523666866 319 SVPLAWMQET-------GVPHSKLNVNggAI--ALGHPLGASGA 353
Cdd:COG0304 304 STPLGDAAETkaikrvfGDHAYKVPVS--STksMTGHLLGAAGA 345
|
|
| PRK06059 |
PRK06059 |
lipid-transfer protein; Provisional |
248-329 |
1.00e-03 |
|
lipid-transfer protein; Provisional
Pssm-ID: 180373 [Multi-domain] Cd Length: 399 Bit Score: 40.90 E-value: 1.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 248 SDGAAALLLMSADTAKKLGLKARA--RVVAFTTV--------------GSDPTLMLTGPI-----AATQKVLAKAGLSIN 306
Cdd:PRK06059 212 SDGAAALIVASKSFARRHLGSVAGvpSVRAISTVtprypqhlpelpdiATDSTAAVPAPErvfkdQILDAAYAEAGIGPE 291
|
90 100
....*....|....*....|...
gi 523666866 307 DIDLFEVNEAFASVPLAWMQETG 329
Cdd:PRK06059 292 DLSLAEVYDLSTALELDWYEHLG 314
|
|
| PRK06158 |
PRK06158 |
thiolase; Provisional |
247-347 |
1.16e-03 |
|
thiolase; Provisional
Pssm-ID: 180434 [Multi-domain] Cd Length: 384 Bit Score: 40.78 E-value: 1.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 247 ISDGAAALLLMSADTAKKLGLK-----ARARVVAFTTVGSDPTLMLTGPIAATQKVLAKAGLSINDIDLFEVNEAFASVP 321
Cdd:PRK06158 208 VTDGAGAVVMVRADRARDLPRPpvyvlGAAAATWHRQISSMPDLTVTAAAESGPRAFAMAGLTPADIDVVELYDAFTINT 287
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 523666866 322 LAWMQETG----------------VPHSKL--NVNGGAIALGHP 347
Cdd:PRK06158 288 ILFLEDLGfcakgeggafveggriAPGGRLpvNTNGGGLSCVHP 331
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
247-353 |
2.29e-03 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 39.83 E-value: 2.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523666866 247 ISDGAAALLLMSADTAKKLGLKARARVV-------AFTTVGSDPTLMltGPIAATQKVLAKAGLSINDIDLfeVN----- 314
Cdd:cd00834 229 LGEGAGVLVLESLEHAKARGAKIYAEILgygassdAYHITAPDPDGE--GAARAMRAALADAGLSPEDIDY--INahgts 304
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 523666866 315 -------EAFAsvplawMQETGVPH-SKLNVNG--GAIalGHPLGASGA 353
Cdd:cd00834 305 tplndaaESKA------IKRVFGEHaKKVPVSStkSMT--GHLLGAAGA 345
|
|
| |
