NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|523670097|ref|WP_020801285|]
View 

MULTISPECIES: aquaporin Z [Pseudomonas]

Protein Classification

aquaporin Z( domain architecture ID 10012387)

aquaporin Z is involved in osmoregulation, allowing water to move into and out of the cell in response to osmotic pressure

CATH:  1.20.1080.10
Gene Ontology:  GO:0055085|GO:0015250|GO:0006833
PubMed:  11964478|11473620|8849412
SCOP:  3000508
TCDB:  1.A.8

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK05420 PRK05420
aquaporin Z; Provisional
 3-230 5.10e-138

aquaporin Z; Provisional


:

Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 386.25  E-value: 5.10e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   3 LFKRSATELVGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKE 82
Cdd:PRK05420   1 MFKKLAAEFFGTFWLVFGGCGSAVLAAAFPELGIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPAKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  83 LPAYIIAQVIGAVIAAALLYFIASGKPGFELAG-GLASNGFGEHSPGGYSMAAGFVCELVMTAMFILIILGATDNRAPAG 161
Cdd:PRK05420  81 LVPYIIAQVVGGIAAAAVLYLIASGKAGFDLAGsGFASNGYGEHSPGGYSLLAALVCEVVLTAFFLLVILGATDKRAPAG 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 523670097 162 LAPIAIGLALTLIHLISIPVTNTSVNPARSTGPALIVGGWAIQQLWMFWVAPLLGAVVGGVLYRWLGKE 230
Cdd:PRK05420 161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTGVALFVGGWALEQLWLFWVAPIVGAIIGGLIYRLLLEK 229
 
Name Accession Description Interval E-value
PRK05420 PRK05420
aquaporin Z; Provisional
 3-230 5.10e-138

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 386.25  E-value: 5.10e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   3 LFKRSATELVGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKE 82
Cdd:PRK05420   1 MFKKLAAEFFGTFWLVFGGCGSAVLAAAFPELGIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPAKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  83 LPAYIIAQVIGAVIAAALLYFIASGKPGFELAG-GLASNGFGEHSPGGYSMAAGFVCELVMTAMFILIILGATDNRAPAG 161
Cdd:PRK05420  81 LVPYIIAQVVGGIAAAAVLYLIASGKAGFDLAGsGFASNGYGEHSPGGYSLLAALVCEVVLTAFFLLVILGATDKRAPAG 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 523670097 162 LAPIAIGLALTLIHLISIPVTNTSVNPARSTGPALIVGGWAIQQLWMFWVAPLLGAVVGGVLYRWLGKE 230
Cdd:PRK05420 161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTGVALFVGGWALEQLWLFWVAPIVGAIIGGLIYRLLLEK 229
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 2-229 2.13e-77

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 232.71  E-value: 2.13e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   2 SLFKRSATELVGTFWLVLGGCGS-AVLAAAFPdvGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPA 80
Cdd:COG0580    1 SLMKRLLAEFLGTFILVLLGCGVvAVLAGTKG--GIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFPW 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  81 KELPAYIIAQVIGAVIAAALLYFIASGKPGfELAGGLASNGFGEHSPG-GYSMAAGFVCELVMTAMFILIILGATDNR-A 158
Cdd:COG0580   79 KDVLPYIIAQLLGAFLGAALVYLIYGGHFD-ATEDGGAKLGVFATSPAiGYSLGAAFLTEIIGTFVLVFVILGITDKRaA 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 523670097 159 PAGLAPIAIGLALTLIHLISIPVTNTSVNPARSTGPALIV----GGWAIQQLWMFWVAPLLGAVVGGVLYRWLGK 229
Cdd:COG0580  158 PGGLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRLFHalgkGGSDWGYLWVPIVAPILGAALAALLYRALFG 232
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 5-225 1.79e-62

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 194.78  E-value: 1.79e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   5 KRSATELVGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKELP 84
Cdd:cd00333    1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGGASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIRVI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  85 AYIIAQVIGAVIAAALLYFIASGK-PGFELAGGLASNGFGEHSPGGYSMAAGFVCELVMTAMFILIILGATDNR---APA 160
Cdd:cd00333   81 PYIIAQLLGAILGAALLYGLYYGLyLEFLGANNIVAGIFGTYPSPGVSNGNAFFVEFIGTFILVLVVFATTDDPngpPPG 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 523670097 161 GLAPIAIGLALTLIHLISIPVTNTSVNPARSTGPALIVGGW-AIQQLWMFWVAPLLGAVVGGVLYR 225
Cdd:cd00333  161 GLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLArHWHYFWVYWVGPLIGAIAGALVYD 226
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 10-224 2.74e-55

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 175.95  E-value: 2.74e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   10 ELVGTFWLVLGGCGSAV---LAAAFPDVGIG-LLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKELPA 85
Cdd:TIGR00861   2 EFLGTFLLVFFGVGSALgvnVAGAYGAVGGGqFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRVPV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   86 YIIAQVIGAVIAAALLYFIASGKPGFELAgglasngFGEHSPGGYSMAAGFVCELVMTAMFILIILGATDNR---APAGL 162
Cdd:TIGR00861  82 YIVAQLIGAILGAALLYGLTSGLFPGNLA-------VNGSASAGVSSGQAFFVEFIGTAILVLVIFATTDDRnrvPRGGF 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 523670097  163 APIAIGLALTLIHLISIPVTNTSVNPARSTGPALIVGGWAIQQLWMFWVAPLLGAVVGGVLY 224
Cdd:TIGR00861 155 APLAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGLAGWGNHWVYWVGPIIGAILGALVY 216
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 10-224 1.58e-45

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 151.32  E-value: 1.58e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   10 ELVGTFWLVLGGCGSAV-LAAAFPDVG-IGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKELPAYI 87
Cdd:pfam00230  14 EFLATLLFVFFGVGSALgVKKLVSSLAvSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLVGRRFSLLRAIFYI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   88 IAQVIGAVIAAALLYFIASgkpgfelaGGLASNGFGEHSPGGYSMAAGFVCELVMTAMFILIILGATDNRAPAGL---AP 164
Cdd:pfam00230  94 VAQLLGAIAGAALLYGVTV--------GLQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTDDRRNGSLgtvAP 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  165 IAIGLALTLIHLISIPVTNTSVNPARSTGPALIvgGWAIQQLWMFWVAPLLGAVVGGVLY 224
Cdd:pfam00230 166 LAIGFAVFLNHLAGGPYTGASMNPARSFGPAVV--LWKWDDHWVYWVGPFIGAALGALVY 223
 
Name Accession Description Interval E-value
PRK05420 PRK05420
aquaporin Z; Provisional
 3-230 5.10e-138

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 386.25  E-value: 5.10e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   3 LFKRSATELVGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKE 82
Cdd:PRK05420   1 MFKKLAAEFFGTFWLVFGGCGSAVLAAAFPELGIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPAKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  83 LPAYIIAQVIGAVIAAALLYFIASGKPGFELAG-GLASNGFGEHSPGGYSMAAGFVCELVMTAMFILIILGATDNRAPAG 161
Cdd:PRK05420  81 LVPYIIAQVVGGIAAAAVLYLIASGKAGFDLAGsGFASNGYGEHSPGGYSLLAALVCEVVLTAFFLLVILGATDKRAPAG 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 523670097 162 LAPIAIGLALTLIHLISIPVTNTSVNPARSTGPALIVGGWAIQQLWMFWVAPLLGAVVGGVLYRWLGKE 230
Cdd:PRK05420 161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTGVALFVGGWALEQLWLFWVAPIVGAIIGGLIYRLLLEK 229
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 2-229 2.13e-77

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 232.71  E-value: 2.13e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   2 SLFKRSATELVGTFWLVLGGCGS-AVLAAAFPdvGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPA 80
Cdd:COG0580    1 SLMKRLLAEFLGTFILVLLGCGVvAVLAGTKG--GIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFPW 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  81 KELPAYIIAQVIGAVIAAALLYFIASGKPGfELAGGLASNGFGEHSPG-GYSMAAGFVCELVMTAMFILIILGATDNR-A 158
Cdd:COG0580   79 KDVLPYIIAQLLGAFLGAALVYLIYGGHFD-ATEDGGAKLGVFATSPAiGYSLGAAFLTEIIGTFVLVFVILGITDKRaA 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 523670097 159 PAGLAPIAIGLALTLIHLISIPVTNTSVNPARSTGPALIV----GGWAIQQLWMFWVAPLLGAVVGGVLYRWLGK 229
Cdd:COG0580  158 PGGLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRLFHalgkGGSDWGYLWVPIVAPILGAALAALLYRALFG 232
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 5-225 1.79e-62

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 194.78  E-value: 1.79e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   5 KRSATELVGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKELP 84
Cdd:cd00333    1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGGASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIRVI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  85 AYIIAQVIGAVIAAALLYFIASGK-PGFELAGGLASNGFGEHSPGGYSMAAGFVCELVMTAMFILIILGATDNR---APA 160
Cdd:cd00333   81 PYIIAQLLGAILGAALLYGLYYGLyLEFLGANNIVAGIFGTYPSPGVSNGNAFFVEFIGTFILVLVVFATTDDPngpPPG 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 523670097 161 GLAPIAIGLALTLIHLISIPVTNTSVNPARSTGPALIVGGW-AIQQLWMFWVAPLLGAVVGGVLYR 225
Cdd:cd00333  161 GLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLArHWHYFWVYWVGPLIGAIAGALVYD 226
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 10-224 2.74e-55

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 175.95  E-value: 2.74e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   10 ELVGTFWLVLGGCGSAV---LAAAFPDVGIG-LLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKELPA 85
Cdd:TIGR00861   2 EFLGTFLLVFFGVGSALgvnVAGAYGAVGGGqFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRVPV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   86 YIIAQVIGAVIAAALLYFIASGKPGFELAgglasngFGEHSPGGYSMAAGFVCELVMTAMFILIILGATDNR---APAGL 162
Cdd:TIGR00861  82 YIVAQLIGAILGAALLYGLTSGLFPGNLA-------VNGSASAGVSSGQAFFVEFIGTAILVLVIFATTDDRnrvPRGGF 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 523670097  163 APIAIGLALTLIHLISIPVTNTSVNPARSTGPALIVGGWAIQQLWMFWVAPLLGAVVGGVLY 224
Cdd:TIGR00861 155 APLAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGLAGWGNHWVYWVGPIIGAILGALVY 216
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 10-224 1.58e-45

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 151.32  E-value: 1.58e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   10 ELVGTFWLVLGGCGSAV-LAAAFPDVG-IGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKELPAYI 87
Cdd:pfam00230  14 EFLATLLFVFFGVGSALgVKKLVSSLAvSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLVGRRFSLLRAIFYI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   88 IAQVIGAVIAAALLYFIASgkpgfelaGGLASNGFGEHSPGGYSMAAGFVCELVMTAMFILIILGATDNRAPAGL---AP 164
Cdd:pfam00230  94 VAQLLGAIAGAALLYGVTV--------GLQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTDDRRNGSLgtvAP 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  165 IAIGLALTLIHLISIPVTNTSVNPARSTGPALIvgGWAIQQLWMFWVAPLLGAVVGGVLY 224
Cdd:pfam00230 166 LAIGFAVFLNHLAGGPYTGASMNPARSFGPAVV--LWKWDDHWVYWVGPFIGAALGALVY 223
PLN00184 PLN00184
aquaporin NIP1; Provisional
 10-224 2.68e-42

aquaporin NIP1; Provisional


Pssm-ID: 177778  Cd Length: 296  Bit Score: 145.16  E-value: 2.68e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  10 ELVGTFWLVLGGCGSAVLAAAFpDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKELPAYIIA 89
Cdd:PLN00184  60 EVLGTYFLVFTGCASVVVNMQN-DNVVTLPGIAIVWGLTIMVLIYSLGHISGAHINPAVTIAFASCGRFPLKQVPAYVIS 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  90 QVIGAVIAAALLYFIasgkpgFELAGGLAS---NGFGEHSPGGYSMAAgFVCELVMTAMFILIILG-ATDNRAPAGLAPI 165
Cdd:PLN00184 139 QVIGSTLAAATLRLL------FGLDHDVCSgkhDVFIGSSPVGSDLQA-FVMEFIVTFYLMFIISGvATDNRAIGELAGL 211

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 523670097 166 AIGLALTLIHLISIPVTNTSVNPARSTGPALIVGGWaiQQLWMFWVAPLLGAVVGGVLY 224
Cdd:PLN00184 212 AIGSTVLLNVLIAAPVSSASMNPGRSLGPAMVYGCY--KGIWIYIVAPTLGAIAGAWVY 268
PLN00182 PLN00182
putative aquaporin NIP4; Provisional
 10-229 1.36e-34

putative aquaporin NIP4; Provisional


Pssm-ID: 165748  Cd Length: 283  Bit Score: 124.64  E-value: 1.36e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  10 ELVGTFWLVLGGCGSAVLAAAFPDVgIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKELPAYIIA 89
Cdd:PLN00182  48 EMIGTYFIIFSGCGVVVVNVLYGGT-ITFPGICVTWGLIVMVMIYSTGHISGAHFNPAVTVTFAIFRRFPWYQVPLYIGA 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  90 QVIGAVIAAALLyfiasgkpgfELAGGLASNGFGEHSPGGySMAAGFVCELVMTAMFILIILG-ATDNRAPAGLAPIAIG 168
Cdd:PLN00182 127 QLTGSLLASLTL----------RLMFNVTPEAFFGTTPTD-SSGQALVAEIIISFLLMFVISGvATDSRAVGELAGIAVG 195

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 523670097 169 LALTLIHLISIPVTNTSVNPARSTGPALIVGGWaiQQLWMFWVAPLLGAVVGGVLY---RWLGK 229
Cdd:PLN00182 196 MTIILNVFVAGPISGASMNPARSLGPAIVMGRY--KGIWVYIVGPFVGIIAGGFVYnliRFTDK 257
PLN00183 PLN00183
putative aquaporin NIP7; Provisional
 10-227 6.10e-29

putative aquaporin NIP7; Provisional


Pssm-ID: 215092  Cd Length: 274  Bit Score: 109.56  E-value: 6.10e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  10 ELVGTFWLVLGGCGsaVLAAAFPDVG-IGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKELPAYII 88
Cdd:PLN00183  51 EMVGTFILMFCVCG--IIASTQLSGGeVGLLEYAATAGLTVVVVVFSIGSISGAHVNPSVTIAFATFGHFPWSKVPLYIT 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  89 AQVIGAVIAAALLYFIASGKPGFELAGGLAsngfgehspggySMAAGFVCELVMTamFILIILGATDNRAPAGLAPIA-- 166
Cdd:PLN00183 129 AQTVGSVLATYVGVSVYGVKADLMTTKPAQ------------GCSSAFWVEFIAT--FIVMFLAASLTSQPQSLGHLSgf 194

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 523670097 167 -IGLALTLIHLISIPVTNTSVNPARSTGPALIvgGWAIQQLWMFWVAPLLGAVVGGVLYRWL 227
Cdd:PLN00183 195 vIGIAIGLAVLITGPVSGGSMNPARSLGPAIV--SWDFKDIWIYITAPTIGAVAGALMFHLL 254
PLN00026 PLN00026
aquaporin NIP; Provisional
 1-224 3.39e-28

aquaporin NIP; Provisional


Pssm-ID: 177663 [Multi-domain]  Cd Length: 298  Bit Score: 108.03  E-value: 3.39e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   1 MSLFKRSATELVGTFWLVLGGCGSAVLAAAFpDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPA 80
Cdd:PLN00026  68 VSLTRKLGAEFVGTFILIFAATAGPIVNQKY-DGAETLIGNAACAGLAVMIVILSTGHISGAHLNPSLTIAFAALRHFPW 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  81 KELPAYIIAQVIGAVIAAallyfiasgkpgFELAGGLASNGFGEHSPGGYSMAAGFVCELVMTAMFILIILG-ATDNRAP 159
Cdd:PLN00026 147 KHVPAYIAAQVSASICAS------------FALKGVFHPFMSGGVTVPSVSTGQAFALEFIITFNLLFVVTAvATDTRAV 214

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 523670097 160 AGLAPIAIGLALTLIHLISIPVTNTSVNPARSTGPALIVGGWaiQQLWMFWVAPLLGAVVGGVLY 224
Cdd:PLN00026 215 GELAGIAVGATVMLNILVAGPSTGGSMNPVRTLGPAVAAGNY--RAIWIYLVAPTLGALAGAGTY 277
PTZ00016 PTZ00016
aquaglyceroporin; Provisional
 10-227 5.76e-25

aquaglyceroporin; Provisional


Pssm-ID: 240230 [Multi-domain]  Cd Length: 294  Bit Score: 99.43  E-value: 5.76e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  10 ELVGTFWLVLGGCGsAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKELPAYIIA 89
Cdd:PTZ00016  56 EFLGTFVLLFFGEG-VVATTHTVGNNGDYLAITIGWGLGVTFGLLVSAGISGGHLNPAVTLGNAVFGKFPWKKLPGYFVA 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  90 QVIGAVIAAALLY------FIASGKPGFELAGGLASNGFGEHSPGGYSMAAGFVCELVMTAMFILIILGATDNR--APAG 161
Cdd:PTZ00016 135 QLLGAFVGAACVYglyygfFKDHGIPELPWETMANGFAGVFATYPREGNFYAIFSELILTAILLLVILAITDPNncPAFN 214

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 523670097 162 LAPIAIGLALTLIHLISIPVTNTSVNPARSTGP----ALIVGGWAIQQ----LWMFWVAPLLGAVVGGVLYRWL 227
Cdd:PTZ00016 215 YLPVAVGLLVFVIGISFGGNTGYALNPARDLGPrlfsAILWGSEVFTKdnyyFWVPLVAPFVGAVLGMFLYDKF 288
PLN00166 PLN00166
aquaporin TIP2; Provisional
 4-224 4.22e-21

aquaporin TIP2; Provisional


Pssm-ID: 165733  Cd Length: 250  Bit Score: 88.46  E-value: 4.22e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   4 FKRSATELVGTFWLVLGGCGSAVLAAAFPDVGI----GLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFP 79
Cdd:PLN00166  18 LKAYLSEFIATLLFVFAGVGSAIAFAKLTSDAAldpaGLVAVAVAHAFALFVGVSIAANISGGHLNPAVTLGLAIGGNIT 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  80 AKELPAYIIAQVIGAVIAAALLYFIASGK--PGFELAGGLASngfgehspggysmAAGFVCELVMTAMFILIILGATDNR 157
Cdd:PLN00166  98 IITGFFYWIAQCLGSIVACLLLVFVTNGEsvPTHGVAAGLGA-------------IEGVVMEIVVTFALVYTVYATAADP 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097 158 APAGL---APIAIGLALTLIHLISIPVTNTSVNPARSTGPALIVGGWAiqQLWMFWVAPLLGAVVGGVLY 224
Cdd:PLN00166 165 KKGSLgtiAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVVSGDFS--QIWIYWVGPLVGGALAGLIY 232
PLN00167 PLN00167
aquaporin TIP5; Provisional
 10-224 2.01e-16

aquaporin TIP5; Provisional


Pssm-ID: 215085  Cd Length: 256  Bit Score: 75.71  E-value: 2.01e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  10 ELVGTFWLVLGGCGSAV----LAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFPAKELPA 85
Cdd:PLN00167  28 EFISTFFFVFAAVGSAMssrkLMPDAASDPSSLLIVAIANAFALSSAVYIAANISGGHVNPAVTFGMAVGGHISVPTAMF 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  86 YIIAQVIGAVIAAALLYFIASGK--PGFELAGGLAsnGFGEHspggysmaagfVCELVMTAMFILIILGATDNR--APAG 161
Cdd:PLN00167 108 YWISQMLASVMACLFLKVTTVGQhvPTYKIAEEMT--GFGAS-----------VLEGVLTFGLVYTVYAAGDPRrgLLGA 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 523670097 162 LAPIAIGLALTLIHLISIPVTNTSVNPARSTGPALIVGGWAIQQLwmFWVAPLLGAVVGGVLY 224
Cdd:PLN00167 175 IGPLAIGLVAGANVLAAGPFSGGSMNPACAFGSAVVAGSFKNQAV--YWVGPLLGGAVAGLLY 235
PLN00027 PLN00027
aquaporin TIP; Provisional
 4-224 2.42e-16

aquaporin TIP; Provisional


Pssm-ID: 177664  Cd Length: 252  Bit Score: 75.59  E-value: 2.42e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097   4 FKRSATELVGTFWLVLGGCGSAVLAAAFPDVG----IGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVSLGLVVGGRFP 79
Cdd:PLN00027  20 LKAALAEFISTLIFVFAGEGSGMAFNKLTDNGsttpAGLVAAALAHAFALFVAVSVGANISGGHVNPAVTFGAFIGGNIT 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523670097  80 AKELPAYIIAQVIGAVIAAALLYFIasgkpgfelAGGLASNGFGEHSpgGYSMAAGFVCELVMT-AMFILIILGATDNR- 157
Cdd:PLN00027 100 LLRGILYWIAQLLGSVVACLLLKFS---------TGGLETSAFSLSS--GVGVWNAFVFEIVMTfGLVYTVYATAVDPKk 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 523670097 158 -APAGLAPIAIGLALTLIHLISIPVTNTSVNPARSTGPALIVGGWAIQqlWMFWVAPLLGAVVGGVLY 224
Cdd:PLN00027 169 gDLGIIAPIAIGFIVGANILAGGAFDGASMNPAVSFGPAVVSWTWTNH--WVYWAGPLIGGGIAGLVY 234
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH