|
Name |
Accession |
Description |
Interval |
E-value |
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
46-383 |
5.50e-92 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 279.14 E-value: 5.50e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 46 KVLVKSISQWDSFNGRIEAVESVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRTYRAALEQAQAALARAKTQASLAQ 125
Cdd:COG0845 2 KVERGDVPETVEATGTVEARREVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPPDLQAALAQAQAQLAAAQAQLELAK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 126 SEANRTDKLVHTNLVSREEWEQRRSAAVQAQADIRAAQAAVDAAQLNLDFTKVTAPIDGRASRALITSGNLVTAGDTasv 205
Cdd:COG0845 82 AELERYKALLKKGAVSQQELDQAKAALDQAQAALAAAQAALEQARANLAYTTIRAPFDGVVGERNVEPGQLVSAGTP--- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 206 LTTLVSQKTVYVYFDVDESTYLHYqnlaRRGQgassdnqalPVEIGLVGEEGYPHQGKVDFLDNQLTPSTGTIRMRALLD 285
Cdd:COG0845 159 LFTIADLDPLEVEFDVPESDLARL----KVGQ---------PVTVTLDAGPGKTFEGKVTFIDPAVDPATRTVRVRAELP 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 286 NSQRLFTPGLFARVRLPGSAEFKATLIDDKAVLTDQDRKYVYIVDKDGKAQRRDITPGRLADGLRIVQKGLNPGDSVIVD 365
Cdd:COG0845 226 NPDGLLRPGMFVRVRIVLGERENALLVPASAVVRDGGGAYVFVVDADGKVERRPVTLGRRDGDQVEVLSGLKAGDRVVVS 305
|
330
....*....|....*...
gi 523681352 366 GLQKVfMPGMPVNAKTVA 383
Cdd:COG0845 306 GLQRL-RDGAKVRVVEAA 322
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
42-377 |
3.72e-77 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 241.06 E-value: 3.72e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 42 VSAAKVLVKSISQWDSFNGRIEAVESVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRTYRAALEQAQAALARAKTQA 121
Cdd:TIGR01730 1 VTVATVESETLANTLTFPGSLEAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDDDYQLALQAALAQLAAAEAQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 122 SLAQSEANRTDKLVHTNLVSREEWEQRRSAAVQAQADIRAAQAAVDAAQLNLDFTKVTAPIDGRASRALITSGNLVTAGD 201
Cdd:TIGR01730 81 ELAQRSFERAERLVKRNAVSQADLDDAKAAVEAAQADLEAAKASLASAQLNLRYTEIRAPFDGTIGRRLVEVGAYVTAGQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 202 TasvLTTLVSQKTVYVYFDVDEstylHYQNLARRGQgassdnqalPVEIGLVGEEGYPHQGKVDFLDNQLTPSTGTIRMR 281
Cdd:TIGR01730 161 T---LATIVDLDPLEADFSVPE----RDLPQLRRGQ---------TLTVELDALPGEEFKGKLRFIDPRVDSGTGTVRVR 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 282 ALLDNSQRLFTPGLFARVRLPGSAEFKATLIDDKAVLTDQDRKYVYIVDKDGKAQRRDITPGRLADGLRIVQKGLNPGDS 361
Cdd:TIGR01730 225 ATFPNPDGRLLPGMFGRVTISLKVRSSAIVVPTQAVIEDLNGKYVYVVKNDGKVSKRPVEVGLRNGGYVEIESGLKAGDQ 304
|
330
....*....|....*.
gi 523681352 362 VIVDGLQKVfMPGMPV 377
Cdd:TIGR01730 305 IVTAGVVKL-RDGAKV 319
|
|
| PRK09578 |
PRK09578 |
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit; |
14-379 |
1.15e-53 |
|
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 169982 [Multi-domain] Cd Length: 385 Bit Score: 182.30 E-value: 1.15e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 14 ALCAMMLSFLLVGCDDSVAQNAAPPAPTVSAAKVLVKSISQWDSFNGRIEAVESVQLRPRVSGYIDKVNYTDGQEVKKGQ 93
Cdd:PRK09578 10 LLAALVALFVLAGCGKGDSDAAAAAPREATVVTVRPTSVPMTVELPGRLDAYRQAEVRARVAGIVTARTYEEGQEVKQGA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 94 VLFTIDDRTYRAAleqaqaalaRAKTQASLAQSEAN---------RTDKLVHTNLVSREEWEQRRSAAVQAQADIRAAQA 164
Cdd:PRK09578 90 VLFRIDPAPLKAA---------RDAAAGALAKAEAAhlaaldkrrRYDDLVRDRAVSERDYTEAVADERQAKAAVASAKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 165 AVDAAQLNLDFTKVTAPIDGRASRALITSGNLVtAGDTASVLTTLVSQKTVYVYFDVDESTYLHYQNLARRGQGASSDNQ 244
Cdd:PRK09578 161 ELARAQLQLDYATVTAPIDGRARRALVTEGALV-GQDQATPLTTVEQLDPIYVNFSQPAADVEALRRAVKSGRATGIAQQ 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 245 ALPVEIGLVGEEGYPHQGKVDFLDNQLTPSTGTIRMRALLDNSQRLFTPGLFARVRLPGSAEFKATLIDDKAVLTDQDRK 324
Cdd:PRK09578 240 DVAVTLVRADGSEYPLKGKLLFSDLAVDPTTDTVAMRALFPNPERELLPGAYVRIALDRAVNPRAILVPRDALLRTADSA 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 523681352 325 YVYIVDKDGKAQRRDITPGRLADGLRIVQKGLNPGDSVIVDGLQKvFMPGMPVNA 379
Cdd:PRK09578 320 SVKVVGQNGKVRDVEVEADQMSGRDWIVTRGLAGGERVIVDNAAQ-FAPGTAVKA 373
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
53-364 |
2.11e-37 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 137.55 E-value: 2.11e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 53 SQWDSFNGRIEAV-ESVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRTYRAALEQAQAALARAKTQASLAQSEANRT 131
Cdd:pfam00529 5 TKGVEAPGRVVVSgNAKAVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAELDRL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 132 DKLVHTNLVSREEWEQRRSAAVQAQADIRAAQAAVDAAQLNLDFTKVTAPIDGRASRALITSGNLVTAGDtASVLTTLVS 211
Cdd:pfam00529 85 QALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTAGALVAQAQ-ANLLATVAQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 212 QKTVYVYFDVDESTYLhyQNLARRGQGASSDNQALPVEIGLVGEEG------YPHQGKVDFLDNQLTPSTGTIRMRALLD 285
Cdd:pfam00529 164 LDQIYVQITQSAAENQ--AEVRSELSGAQLQIAEAEAELKLAKLDLerteirAPVDGTVAFLSVTVDGGTVSAGLRLMFV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 286 N-SQRLFTPGLFARVRLPGSAEFKATLIDDKAVLTDQDRKY-VYIVDKDGKAQRRDITPGRLADGLRIVQKGLNPGDSVI 363
Cdd:pfam00529 242 VpEDNLLVPGMFVETQLDQVRVGQPVLIPFDAFPQTKTGRFtGVVVGISPDTGPVRVVVDKAQGPYYPLRIGLSAGALVR 321
|
.
gi 523681352 364 V 364
Cdd:pfam00529 322 L 322
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
46-383 |
5.50e-92 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 279.14 E-value: 5.50e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 46 KVLVKSISQWDSFNGRIEAVESVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRTYRAALEQAQAALARAKTQASLAQ 125
Cdd:COG0845 2 KVERGDVPETVEATGTVEARREVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPPDLQAALAQAQAQLAAAQAQLELAK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 126 SEANRTDKLVHTNLVSREEWEQRRSAAVQAQADIRAAQAAVDAAQLNLDFTKVTAPIDGRASRALITSGNLVTAGDTasv 205
Cdd:COG0845 82 AELERYKALLKKGAVSQQELDQAKAALDQAQAALAAAQAALEQARANLAYTTIRAPFDGVVGERNVEPGQLVSAGTP--- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 206 LTTLVSQKTVYVYFDVDESTYLHYqnlaRRGQgassdnqalPVEIGLVGEEGYPHQGKVDFLDNQLTPSTGTIRMRALLD 285
Cdd:COG0845 159 LFTIADLDPLEVEFDVPESDLARL----KVGQ---------PVTVTLDAGPGKTFEGKVTFIDPAVDPATRTVRVRAELP 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 286 NSQRLFTPGLFARVRLPGSAEFKATLIDDKAVLTDQDRKYVYIVDKDGKAQRRDITPGRLADGLRIVQKGLNPGDSVIVD 365
Cdd:COG0845 226 NPDGLLRPGMFVRVRIVLGERENALLVPASAVVRDGGGAYVFVVDADGKVERRPVTLGRRDGDQVEVLSGLKAGDRVVVS 305
|
330
....*....|....*...
gi 523681352 366 GLQKVfMPGMPVNAKTVA 383
Cdd:COG0845 306 GLQRL-RDGAKVRVVEAA 322
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
42-377 |
3.72e-77 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 241.06 E-value: 3.72e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 42 VSAAKVLVKSISQWDSFNGRIEAVESVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRTYRAALEQAQAALARAKTQA 121
Cdd:TIGR01730 1 VTVATVESETLANTLTFPGSLEAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDDDYQLALQAALAQLAAAEAQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 122 SLAQSEANRTDKLVHTNLVSREEWEQRRSAAVQAQADIRAAQAAVDAAQLNLDFTKVTAPIDGRASRALITSGNLVTAGD 201
Cdd:TIGR01730 81 ELAQRSFERAERLVKRNAVSQADLDDAKAAVEAAQADLEAAKASLASAQLNLRYTEIRAPFDGTIGRRLVEVGAYVTAGQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 202 TasvLTTLVSQKTVYVYFDVDEstylHYQNLARRGQgassdnqalPVEIGLVGEEGYPHQGKVDFLDNQLTPSTGTIRMR 281
Cdd:TIGR01730 161 T---LATIVDLDPLEADFSVPE----RDLPQLRRGQ---------TLTVELDALPGEEFKGKLRFIDPRVDSGTGTVRVR 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 282 ALLDNSQRLFTPGLFARVRLPGSAEFKATLIDDKAVLTDQDRKYVYIVDKDGKAQRRDITPGRLADGLRIVQKGLNPGDS 361
Cdd:TIGR01730 225 ATFPNPDGRLLPGMFGRVTISLKVRSSAIVVPTQAVIEDLNGKYVYVVKNDGKVSKRPVEVGLRNGGYVEIESGLKAGDQ 304
|
330
....*....|....*.
gi 523681352 362 VIVDGLQKVfMPGMPV 377
Cdd:TIGR01730 305 IVTAGVVKL-RDGAKV 319
|
|
| PRK09578 |
PRK09578 |
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit; |
14-379 |
1.15e-53 |
|
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 169982 [Multi-domain] Cd Length: 385 Bit Score: 182.30 E-value: 1.15e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 14 ALCAMMLSFLLVGCDDSVAQNAAPPAPTVSAAKVLVKSISQWDSFNGRIEAVESVQLRPRVSGYIDKVNYTDGQEVKKGQ 93
Cdd:PRK09578 10 LLAALVALFVLAGCGKGDSDAAAAAPREATVVTVRPTSVPMTVELPGRLDAYRQAEVRARVAGIVTARTYEEGQEVKQGA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 94 VLFTIDDRTYRAAleqaqaalaRAKTQASLAQSEAN---------RTDKLVHTNLVSREEWEQRRSAAVQAQADIRAAQA 164
Cdd:PRK09578 90 VLFRIDPAPLKAA---------RDAAAGALAKAEAAhlaaldkrrRYDDLVRDRAVSERDYTEAVADERQAKAAVASAKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 165 AVDAAQLNLDFTKVTAPIDGRASRALITSGNLVtAGDTASVLTTLVSQKTVYVYFDVDESTYLHYQNLARRGQGASSDNQ 244
Cdd:PRK09578 161 ELARAQLQLDYATVTAPIDGRARRALVTEGALV-GQDQATPLTTVEQLDPIYVNFSQPAADVEALRRAVKSGRATGIAQQ 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 245 ALPVEIGLVGEEGYPHQGKVDFLDNQLTPSTGTIRMRALLDNSQRLFTPGLFARVRLPGSAEFKATLIDDKAVLTDQDRK 324
Cdd:PRK09578 240 DVAVTLVRADGSEYPLKGKLLFSDLAVDPTTDTVAMRALFPNPERELLPGAYVRIALDRAVNPRAILVPRDALLRTADSA 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 523681352 325 YVYIVDKDGKAQRRDITPGRLADGLRIVQKGLNPGDSVIVDGLQKvFMPGMPVNA 379
Cdd:PRK09578 320 SVKVVGQNGKVRDVEVEADQMSGRDWIVTRGLAGGERVIVDNAAQ-FAPGTAVKA 373
|
|
| PRK15030 |
PRK15030 |
multidrug efflux RND transporter periplasmic adaptor subunit AcrA; |
9-382 |
1.05e-51 |
|
multidrug efflux RND transporter periplasmic adaptor subunit AcrA;
Pssm-ID: 184990 [Multi-domain] Cd Length: 397 Bit Score: 177.60 E-value: 1.05e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 9 NIHLTALCAMML---SFLLVGCDDSVAQNAAPPAPTVSAAKVLVKSISQWDSFNGRIEAVESVQLRPRVSGYIDKVNYTD 85
Cdd:PRK15030 4 NRGFTPLAVVLMlsgSLALTGCDDKQAQQGGQQMPAVGVVTVKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 86 GQEVKKGQVLFTIDDRTYRAALEQAQAALARAKTQASLAQSEANRTDKLVHTNLVSREEWEQRRSAAVQAQADIRAAQAA 165
Cdd:PRK15030 84 GSDIEAGVSLYQIDPATYQATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 166 VDAAQLNLDFTKVTAPIDGRASRALITSGNLVTAGDtASVLTTLvsQKTVYVYFDVDEST--YLHYQNLARRGQGASSDN 243
Cdd:PRK15030 164 VETARINLAYTKVTSPISGRIGKSNVTEGALVQNGQ-ATALATV--QQLDPIYVDVTQSSndFLRLKQELANGTLKQENG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 244 QAlpvEIGLVGEEG--YPHQGKVDFLDNQLTPSTGTIRMRALLDNSQRLFTPGLFARVRLPGSAEFKATLIDDKAVL-TD 320
Cdd:PRK15030 241 KA---KVSLITSDGikFPQDGTLEFSDVTVDQTTGSITLRAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTrTP 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 523681352 321 QDRKYVYIVDKDGKAQRRDITPGRLADGLRIVQKGLNPGDSVIVDGLQKVfMPGMPVNAKTV 382
Cdd:PRK15030 318 RGDATVLVVGADDKVETRPIVASQAIGDKWLVTEGLKAGDRVVISGLQKV-RPGVQVKAQEV 378
|
|
| PRK09859 |
PRK09859 |
multidrug transporter subunit MdtE; |
23-389 |
5.49e-47 |
|
multidrug transporter subunit MdtE;
Pssm-ID: 137559 [Multi-domain] Cd Length: 385 Bit Score: 164.89 E-value: 5.49e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 23 LLVGCDDSVAQNAAPPAPTVSAAKVLVKSISQWDSFNGRIEAVESVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRT 102
Cdd:PRK09859 17 MLTACDDKSAENAAAMTPEVGVVTLSPGSVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAP 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 103 YRAALEQAQAALARAKTQASLAQSEANRTDKLVHTNLVSREEWEQRRSAAVQAQADIRAAQAAVDAAQLNLDFTKVTAPI 182
Cdd:PRK09859 97 LQAELNSAKGSLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAVEQATINLQYANVTSPI 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 183 DGRASRALITSGNLVTAGDTASVLTTlvsQKTVYVYFDVDEST--YLHYQNLARRGQGASSDNQAlPVEIGLVGEEGYPH 260
Cdd:PRK09859 177 TGVSGKSSVTVGALVTANQADSLVTV---QRLDPIYVDLTQSVqdFLRMKEEVASGQIKQVQGST-PVQLNLENGKRYSQ 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 261 QGKVDFLDNQLTPSTGTIRMRALLDNSQRLFTPGLFARVRLPGSAEFKATLIDDKAVLTD-QDRKYVYIVDKDGKAQRRD 339
Cdd:PRK09859 253 TGTLKFSDPTVDETTGSVTLRAIFPNPNGDLLPGMYVTALVDEGSRQNVLLVPQEGVTHNaQGKATALILDKDDVVQLRE 332
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 523681352 340 ITPGRLADGLRIVQKGLNPGDSVIVDGLQKVfMPGMPVNAKTVAMTSSAT 389
Cdd:PRK09859 333 IEASKAIGDQWVVTSGLQAGDRVIVSGLQRI-RPGIKARAISSSQENAST 381
|
|
| PRK11556 |
PRK11556 |
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit; |
36-369 |
2.10e-42 |
|
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 183194 [Multi-domain] Cd Length: 415 Bit Score: 153.41 E-value: 2.10e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 36 APPAPTVSAAKVLVKSISQWDSFNGRIEAVESVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRTYRAALEQAQAALa 115
Cdd:PRK11556 56 SGPLAPVQAATATEQAVPRYLTGLGTVTAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPRPFKVALAQAQGQL- 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 116 rAKTQASL--AQSEANRTDKLVHTNLVSREEWEQRRSAAVQAQADIRAAQAAVDAAQLNLDFTKVTAPIDGRASRALITS 193
Cdd:PRK11556 135 -AKDQATLanARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDYSRITAPISGRVGLKQVDV 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 194 GNLVTAGDTASVLtTLVSQKTVYVYFDVDEStylhyqNLARRGQgASSDNQALPVEIGLVGEEGYPHQGKVDFLDNQLTP 273
Cdd:PRK11556 214 GNQISSGDTTGIV-VITQTHPIDLVFTLPES------DIATVVQ-AQKAGKPLVVEAWDRTNSKKLSEGTLLSLDNQIDA 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 274 STGTIRMRALLDNSQRLFTPGLFARVRLPGSAEFKATLIDDKAVLTDQDRKYVYIVDKDGKAQRRDITPGrLADGLRIV- 352
Cdd:PRK11556 286 TTGTIKLKARFNNQDDALFPNQFVNARMLVDTLQNAVVIPTAALQMGNEGHFVWVLNDENKVSKHLVTPG-IQDSQKVVi 364
|
330
....*....|....*..
gi 523681352 353 QKGLNPGDSVIVDGLQK 369
Cdd:PRK11556 365 SAGLSAGDRVVTDGIDR 381
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
53-364 |
2.11e-37 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 137.55 E-value: 2.11e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 53 SQWDSFNGRIEAV-ESVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRTYRAALEQAQAALARAKTQASLAQSEANRT 131
Cdd:pfam00529 5 TKGVEAPGRVVVSgNAKAVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAELDRL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 132 DKLVHTNLVSREEWEQRRSAAVQAQADIRAAQAAVDAAQLNLDFTKVTAPIDGRASRALITSGNLVTAGDtASVLTTLVS 211
Cdd:pfam00529 85 QALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTAGALVAQAQ-ANLLATVAQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 212 QKTVYVYFDVDESTYLhyQNLARRGQGASSDNQALPVEIGLVGEEG------YPHQGKVDFLDNQLTPSTGTIRMRALLD 285
Cdd:pfam00529 164 LDQIYVQITQSAAENQ--AEVRSELSGAQLQIAEAEAELKLAKLDLerteirAPVDGTVAFLSVTVDGGTVSAGLRLMFV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 286 N-SQRLFTPGLFARVRLPGSAEFKATLIDDKAVLTDQDRKY-VYIVDKDGKAQRRDITPGRLADGLRIVQKGLNPGDSVI 363
Cdd:pfam00529 242 VpEDNLLVPGMFVETQLDQVRVGQPVLIPFDAFPQTKTGRFtGVVVGISPDTGPVRVVVDKAQGPYYPLRIGLSAGALVR 321
|
.
gi 523681352 364 V 364
Cdd:pfam00529 322 L 322
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
59-301 |
1.37e-26 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 108.60 E-value: 1.37e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 59 NGRIEAvESVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRTYR---------------------------AALEQAQ 111
Cdd:COG1566 38 DGRVEA-RVVTVAAKVSGRVTEVLVKEGDRVKKGQVLARLDPTDLQaalaqaeaqlaaaeaqlarleaelgaeAEIAAAE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 112 AALARAKTQASLAQSEANRTDKLVHTNLVSREEWEQRRSAAVQAQADIRAAQAAVDAAQ--------------------- 170
Cdd:COG1566 117 AQLAAAQAQLDLAQRELERYQALYKKGAVSQQELDEARAALDAAQAQLEAAQAQLAQAQaglreeeelaaaqaqvaqaea 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 171 ------LNLDFTKVTAPIDGRASRALITSGNLVTAGDTasvLTTLVSQKTVYVYFDVDEsTYLHYqnlARRGQgassdnq 244
Cdd:COG1566 197 alaqaeLNLARTTIRAPVDGVVTNLNVEPGEVVSAGQP---LLTIVPLDDLWVEAYVPE-TDLGR---VKPGQ------- 262
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 523681352 245 alPVEIGLVGEEGYPHQGKVDFL----------DNQLTPSTGTIRMRALLDNSQ-RLFTPGLFARVRL 301
Cdd:COG1566 263 --PVEVRVDAYPDRVFEGKVTSIspgagftsppKNATGNVVQRYPVRIRLDNPDpEPLRPGMSATVEI 328
|
|
| PRK11578 |
PRK11578 |
macrolide transporter subunit MacA; Provisional |
38-364 |
8.37e-15 |
|
macrolide transporter subunit MacA; Provisional
Pssm-ID: 183211 [Multi-domain] Cd Length: 370 Bit Score: 75.20 E-value: 8.37e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 38 PAPTVSAAKVLVKSISQWDSFNGRIEAVESVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDD-------RTYRAALEQA 110
Cdd:PRK11578 32 PVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPeqaenqiKEVEATLMEL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 111 QAALARAKTQASLAQSEANRTDKLVHTNLVSREEWEQRRS--AAVQAQ-----ADIRAAQAAVDAAQLNLDFTKVTAPID 183
Cdd:PRK11578 112 RAQRQQAEAELKLARVTLSRQQRLAKTQAVSQQDLDTAATelAVKQAQigtidAQIKRNQASLDTAKTNLDYTRIVAPMA 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 184 GRASRALITSGNLVTAGDTASVLTTLVSQKTVYVYFDVDESTYLHYqnlaRRGQGASsdnqalpveIGLVGEEGYPHQGK 263
Cdd:PRK11578 192 GEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHL----KPGQKAW---------FTVLGDPLTRYEGV 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 264 VDflDNQLTPS--TGTIRMRALLD--NSQRLFTPGLFARVRLPgSAEFKATLIDDKAVLTDQ--DRKYVYIVDKDGKAQR 337
Cdd:PRK11578 259 LK--DILPTPEkvNDAIFYYARFEvpNPNGLLRLDMTAQVHIQ-LTDVKNVLTIPLSALGDPvgDNRYKVKLLRNGETRE 335
|
330 340
....*....|....*....|....*..
gi 523681352 338 RDITPGRLADGLRIVQKGLNPGDSVIV 364
Cdd:PRK11578 336 REVTIGARNDTDVEIVKGLEAGDEVII 362
|
|
| PRK10559 |
PRK10559 |
p-hydroxybenzoic acid efflux pump subunit AaeA; |
68-217 |
3.46e-13 |
|
p-hydroxybenzoic acid efflux pump subunit AaeA;
Pssm-ID: 182548 [Multi-domain] Cd Length: 310 Bit Score: 69.77 E-value: 3.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 68 VQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRTYRAALEQAQAALARAKTQASLAQSEANRTDKLvHTNLVSREEWEQ 147
Cdd:PRK10559 48 VAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALAEAEADVAYYQVLAQEKRREAGRRNRL-GVQAMSREEIDQ 126
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 148 RRSAAVQAQADIRAAQAAVDAAQLNLDFTKVTAPIDGRASRALITSGNLVTAGDTAsvlTTLVSQKTVYV 217
Cdd:PRK10559 127 ANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTA---VALVKQNSFYV 193
|
|
| HlyD_D23 |
pfam16576 |
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and ... |
60-297 |
4.62e-12 |
|
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.
Pssm-ID: 435440 [Multi-domain] Cd Length: 214 Bit Score: 64.84 E-value: 4.62e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 60 GRIEAVES--VQLRPRVSGYIDK--VNYTdGQEVKKGQVLFTIDdrtyraaleqaqaalaraKTQASLAQSE----ANRT 131
Cdd:pfam16576 10 GRVAYDERrlAHVHARVEGWIEKlyVNAT-GDPVKKGQPLAELY------------------SPELVAAQQEyllaLRSG 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 132 DKLVHTNLVSREEwEQRRSAAVQAqADIRAAQAAVDAAQLnldFTkVTAPIDGRASRALITSGNLVTAGDTasvLTTLVS 211
Cdd:pfam16576 71 DALSKSELLRAAR-QRLRLLGMPE-AQIAELERTGKVQPT---VT-VYAPISGVVTELNVREGMYVQPGDT---LFTIAD 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 212 QKTVYVYFDVDEstylHYQNLARRGQGASSDNQALPveiglvgeeGYPHQGKVDFLDNQLTPSTGTIRMRALLDNSQRLF 291
Cdd:pfam16576 142 LSTVWVEADVPE----QDLALVKVGQPAEVTLPALP---------GKTFEGKVDYIYPTLDPKTRTVRVRIELPNPDGRL 208
|
....*.
gi 523681352 292 TPGLFA 297
Cdd:pfam16576 209 KPGMFA 214
|
|
| Biotin_lipoyl_2 |
pfam13533 |
Biotin-lipoyl like; |
66-104 |
3.01e-09 |
|
Biotin-lipoyl like;
Pssm-ID: 433286 Cd Length: 50 Bit Score: 52.45 E-value: 3.01e-09
10 20 30
....*....|....*....|....*....|....*....
gi 523681352 66 ESVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRTYR 104
Cdd:pfam13533 1 PVVKIASPVSGKVVAVNVKEGQQVKKGDVLATLDSPELQ 39
|
|
| PRK10476 |
PRK10476 |
multidrug transporter subunit MdtN; |
66-217 |
8.71e-07 |
|
multidrug transporter subunit MdtN;
Pssm-ID: 182488 [Multi-domain] Cd Length: 346 Bit Score: 50.41 E-value: 8.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 66 ESVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRTY----------------------------RAALEQAQAALARA 117
Cdd:PRK10476 47 DVVHVASEVGGRIVELAVTENQAVKKGDLLFRIDPRPYeltvaqaqadlaladaqimttqrsvdaeRSNAASANEQVERA 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 118 KTQASLAQSEANRTDKLVHTNLVSREEWEQ----RRSAAV---QAQ-----------------ADIRAAQAAVDAAQLNL 173
Cdd:PRK10476 127 RANAKLATRTLERLEPLLAKGYVSAQQVDQartaQRDAEVslnQALlqaqaaaaavggvdalvAQRAAREAALAIAELHL 206
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 523681352 174 DFTKVTAPIDGRASRALITSGNLVTAgdtASVLTTLVSQKTVYV 217
Cdd:PRK10476 207 EDTTVRAPFDGRVVGLKVSVGEFAAP---MQPIFTLIDTDHWYA 247
|
|
| PRK09783 |
PRK09783 |
copper/silver efflux system membrane fusion protein CusB; Provisional |
273-367 |
8.29e-06 |
|
copper/silver efflux system membrane fusion protein CusB; Provisional
Pssm-ID: 236625 [Multi-domain] Cd Length: 409 Bit Score: 47.55 E-value: 8.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 273 PSTGTIRMRALLDNSQRLFTPGLFARVRLPGSAEfKATLIDDKAVLTDQDRKYVYIVDKDGKAQRRDITPGRLADGLRIV 352
Cdd:PRK09783 291 AATRTLQLRLEVDNADEALKPGMNAWLQLNTASE-PMLLIPSQALIDTGSEQRVITVDADGRFVPKRVAVFQESQGVTAI 369
|
90
....*....|....*
gi 523681352 353 QKGLNPGDSVIVDGL 367
Cdd:PRK09783 370 RSGLAEGEKVVSSGL 384
|
|
| HlyD_3 |
pfam13437 |
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator ... |
177-294 |
4.85e-05 |
|
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator HlyD proteins.
Pssm-ID: 433206 [Multi-domain] Cd Length: 104 Bit Score: 41.96 E-value: 4.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 177 KVTAPIDGRASRALITSGNLVTAGDtasVLTTLVSQKTVYVYFDVDEstylhyQNLARRGQGAssdnqalPVEIGLVGEE 256
Cdd:pfam13437 1 TIRAPVDGVVAELNVEEGQVVQAGD---PLATIVPPDRLLVEAFVPA------ADLGSLKKGQ-------KVTLKLDPGS 64
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 523681352 257 GYPHQGKVDFLDNQLTPSTGTIRMRALLDNS--QRLFTPG 294
Cdd:pfam13437 65 DYTLEGKVVRISPTVDPDTGVIPVRVSIENPktPIPLLPG 104
|
|
| PRK03598 |
PRK03598 |
putative efflux pump membrane fusion protein; Provisional |
67-266 |
1.33e-04 |
|
putative efflux pump membrane fusion protein; Provisional
Pssm-ID: 235136 [Multi-domain] Cd Length: 331 Bit Score: 43.41 E-value: 1.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 67 SVQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRTYRAALEQAQAALARAKTQ-----------------ASLAQSEA- 128
Cdd:PRK03598 43 TVNLGFRVGGRLASLAVDEGDAVKAGQVLGELDAAPYENALMQAKANVSVAQAQldlmlagyrdeeiaqarAAVKQAQAa 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 129 --------NRTDKLVHTNLVSREEWEQRRSAAVQAQADIRAAQA--------------------------AVDAAQLNLD 174
Cdd:PRK03598 123 ydyaqnfyNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDklsqyregnrpqdiaqakaslaqaqaALAQAELNLQ 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 175 FTKVTAPIDGRA-SRAlITSGNLVTAGDTASVLTTlvsQKTVYVYFDVDEStylhyqNLARRGQGassdnqaLPVEIGLV 253
Cdd:PRK03598 203 DTELIAPSDGTIlTRA-VEPGTMLNAGSTVFTLSL---TRPVWVRAYVDER------NLGQAQPG-------RKVLLYTD 265
|
250
....*....|...
gi 523681352 254 GEEGYPHQGKVDF 266
Cdd:PRK03598 266 GRPDKPYHGQIGF 278
|
|
| PRK15136 |
PRK15136 |
multidrug efflux MFS transporter periplasmic adaptor subunit EmrA; |
68-188 |
3.74e-04 |
|
multidrug efflux MFS transporter periplasmic adaptor subunit EmrA;
Pssm-ID: 185090 [Multi-domain] Cd Length: 390 Bit Score: 42.37 E-value: 3.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 68 VQLRPRVSGYIDKVNYTDGQEVKKGQVLFTIDDRtyraaleQAQAALARAKT-------------------QASL----- 123
Cdd:PRK15136 62 VQIMSQVSGSVTKVWADNTDFVKEGDVLVTLDPT-------DAEQAFEKAKTalansvrqthqlminskqyQANIelqkt 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523681352 124 ----AQSEANRTDKLVHTNLVSREEWEQRRSAAVQAQAD-------------------------IRAAQAAVDAAQLNLD 174
Cdd:PRK15136 135 alaqAQSDLNRRVPLGNANLIGREELQHARDAVASAQAQldvaiqqynanqamilntpledqpaVQQAATEVRNAWLALQ 214
|
170
....*....|....
gi 523681352 175 FTKVTAPIDGRASR 188
Cdd:PRK15136 215 RTKIVSPMTGYVSR 228
|
|
| |
