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Conserved domains on  [gi|523697111|ref|WP_020815474|]
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ABC transporter permease [Ruminiclostridium papyrosolvens]

Protein Classification

ABC transporter permease( domain architecture ID 10003058)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates such as monosaccharide sugars such as xylose, arabinose, and fructose

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AraH COG1172
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ...
 14-317 1.56e-104

Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440785  Cd Length: 322  Bit Score: 309.34  E-value: 1.56e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  14 KKYSIFMVLFVLFIICSLANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSGVFAISAYKATG-S 92
Cdd:COG1172   17 PELGLLLALVLLLVVFSILSPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSVGSVVALSGVVAALLLVALGlP 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  93 LVVAVLVGIITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKGQNILQLDK-FVVFGQGSVGVIPIPIIFLV 171
Cdd:COG1172   97 ILLAILLALLVGALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLLTGGRPISGLPDaFRALGQGSLLGIPVPVLIAL 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 172 ALAIVTWYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTA 251
Cdd:COG1172  177 VVALVAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQPNAGSGYELDAIAA 256

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 523697111 252 AIIGGTSFSGGVGTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVIYDIQSKNRRTK 317
Cdd:COG1172  257 VVIGGTSLTGGRGSVLGTLLGALILGVLNNGLNLLGVSSYWQQIVKGAIILLAVLLDRLRRRRRAR 322
 
Name Accession Description Interval E-value
AraH COG1172
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ...
 14-317 1.56e-104

Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440785  Cd Length: 322  Bit Score: 309.34  E-value: 1.56e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  14 KKYSIFMVLFVLFIICSLANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSGVFAISAYKATG-S 92
Cdd:COG1172   17 PELGLLLALVLLLVVFSILSPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSVGSVVALSGVVAALLLVALGlP 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  93 LVVAVLVGIITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKGQNILQLDK-FVVFGQGSVGVIPIPIIFLV 171
Cdd:COG1172   97 ILLAILLALLVGALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLLTGGRPISGLPDaFRALGQGSLLGIPVPVLIAL 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 172 ALAIVTWYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTA 251
Cdd:COG1172  177 VVALVAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQPNAGSGYELDAIAA 256

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 523697111 252 AIIGGTSFSGGVGTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVIYDIQSKNRRTK 317
Cdd:COG1172  257 VVIGGTSLTGGRGSVLGTLLGALILGVLNNGLNLLGVSSYWQQIVKGAIILLAVLLDRLRRRRRAR 322
TM_PBP1_transp_AraH_like cd06579
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the ...
 50-308 1.75e-83

Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.


Pssm-ID: 119321 [Multi-domain]  Cd Length: 263  Bit Score: 253.49  E-value: 1.75e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  50 AVTTILAFGQTILIISGMLDLSQGSVLALSGVFAISAYKATG-SLVVAVLVGIITGVVCNFINALMISTFKAPPFIATLA 128
Cdd:cd06579    2 AVLGILALGMTLVIITGGIDLSVGSVAALSAVVAALLLVNAGlPIPLAILAALAVGALIGLLNGLLVAYLRIPPFIVTLG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 129 MLTMARGVALLYTKGQNILQLDKF--VVFGQGSVGVIPIPIIFLVALAIVTWYILKHTRIGRSLYAVGGNEEASVASGIN 206
Cdd:cd06579   82 TMFILRGLALLITGGRPISGLPPLfsFFLGGGLILGIPVPVLIALAVALVAWFLLRRTRFGRYLYAVGGNPEAARLSGIN 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 207 VHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTAAIIGGTSFSGGVGTATGTLAGAFIVGFLDNIMNLT 286
Cdd:cd06579  162 VRRVKILAYVLSGLLAGLAGILLAARLGSAQPTAGNGYELDAIAAVVLGGTSLTGGRGSVLGTLLGALLLGVLNNGLNLL 241

                        250       260
                 ....*....|....*....|..
gi 523697111 287 SVDSYMQQIVRGAIIALAVIYD 308
Cdd:cd06579  242 GVSSFWQQIVKGAILLLAVALD 263
rbsC PRK09512
ribose ABC transporter permease protein; Reviewed
 22-312 1.53e-74

ribose ABC transporter permease protein; Reviewed


Pssm-ID: 181922 [Multi-domain]  Cd Length: 320  Bit Score: 232.69  E-value: 1.53e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  22 LFVLFIICSLANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSGVFAISAYKATGSLVVAVLVGI 101
Cdd:PRK09512  25 LLVLIAIVSTLSPNFFTVNNLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVPAAL 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 102 ITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKGQNIL-----QLDKFVVFGQGSVGVIPIPIIFLVALAIV 176
Cdd:PRK09512 105 ALGAAIGAVTGVIVAKGKVQAFIATLVMMLLLRGVTMVYTDGSPINtgftdNADLFGWFGIGRPLGIPTPVWIMAIVFLA 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 177 TWYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTAAIIGG 256
Cdd:PRK09512 185 AWYMLHHTRLGRYIYALGGNEAATRLSGINVNKVKIIVYALCGLLAALAGIIEVARLSSAQPTAGTGYELDAIAAVVLGG 264

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 523697111 257 TSFSGGVGTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVIYDIQSK 312
Cdd:PRK09512 265 TSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ 320
GguB NF040906
sugar ABC transporter permease;
14-314 3.23e-45

sugar ABC transporter permease;


Pssm-ID: 468841 [Multi-domain]  Cd Length: 375  Bit Score: 158.01  E-value: 3.23e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  14 KKYSIFMVLFVLFIICS-LANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSG-VFAISAYKATG 91
Cdd:NF040906   3 RQYGMLIALVAIVVLFQiLTGGILLRPLNVTNLILQNSYILILAIGMLLVIIAGHIDLSVGSVVAFVGaVAAVLMVNWGM 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  92 SLVVAVLVGIITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKGQNI------------------------- 146
Cdd:NF040906  83 PWWLAVLLCLLVGALIGAWQGFWVAYVGIPAFIVTLAGMLVFRGLTLVVLGGQSIgpfpdgfqkissgflpdlfggtglh 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 147 -----------------------------LQLDKFVVFGQGSVGV----------------IPIPIIFLVALAIVTWYIL 181
Cdd:NF040906 163 lltlllgvlaaaalvwsqlrgrrrrikygLEVEPMALFIAKLVLIaaailfftyllasyrgLPNVLIILGVLILVYSFVT 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 182 KHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTAAIIGGTSFSG 261
Cdd:NF040906 243 NRTVIGRHIYAVGGNEKAAKLSGIKTKRVTFLVFVNMGVLAALAGLVFAARLNSATPKAGNGFELDAIAACFIGGASASG 322

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 523697111 262 GVGTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVIYDIQSKNR 314
Cdd:NF040906 323 GVGTVVGAIIGALVMGVLNNGMSILGIGIDWQQVIKGLVLLAAVAFDVYNKRK 375
BPD_transp_2 pfam02653
Branched-chain amino acid transport system / permease component; This is a large family mainly ...
 41-305 4.94e-29

Branched-chain amino acid transport system / permease component; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease and a ribose transport system.


Pssm-ID: 396977 [Multi-domain]  Cd Length: 269  Bit Score: 112.74  E-value: 4.94e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111   41 NLTNISRQLAVTTILAFGQTILI-ISGMLDLSQGSVLALSGVFAISAYKATGSLV-VAVLVGIITGVVCNFINALMISTF 118
Cdd:pfam02653   1 NILNILTLASIYAIAALGLTLIYgIAGVINLGHGGFMMLGAYVAAMLLNLLGPGLwLALPVGILVGAAVGLLIGILTLRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  119 KAPPFIATLAMLTMARGVALLY----TKGQNILQLDKFVVFGQG---SVGVIPIPIIFLVALAIVtWYILKHTRIGRSLY 191
Cdd:pfam02653  81 KINEVIITLLLNLAALGLALFLvtgiLGGEGGTSGITGPSGFPGaflSFAFAFIFLLALLLVLAL-WLLLYRTKFGRALR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  192 AVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGA-VGYEFTALTAAIIGGTsfsggvGTATGTL 270
Cdd:pfam02653 160 AVGENEEAARAAGINVKKLKLLTFVISGALAGLAGALLALYTGVVPPSNFgVGLGLDAIAAVVLGGA------GSPIGVV 233

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 523697111  271 AGAFIVGFLDNIM-NLTSVDSYMQQIVRGAIIALAV 305
Cdd:pfam02653 234 IGSLIIGLVQSLGlGALGSPPELSLLVLGALLILVL 269
 
Name Accession Description Interval E-value
AraH COG1172
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ...
 14-317 1.56e-104

Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440785  Cd Length: 322  Bit Score: 309.34  E-value: 1.56e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  14 KKYSIFMVLFVLFIICSLANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSGVFAISAYKATG-S 92
Cdd:COG1172   17 PELGLLLALVLLLVVFSILSPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSVGSVVALSGVVAALLLVALGlP 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  93 LVVAVLVGIITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKGQNILQLDK-FVVFGQGSVGVIPIPIIFLV 171
Cdd:COG1172   97 ILLAILLALLVGALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLLTGGRPISGLPDaFRALGQGSLLGIPVPVLIAL 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 172 ALAIVTWYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTA 251
Cdd:COG1172  177 VVALVAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQPNAGSGYELDAIAA 256

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 523697111 252 AIIGGTSFSGGVGTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVIYDIQSKNRRTK 317
Cdd:COG1172  257 VVIGGTSLTGGRGSVLGTLLGALILGVLNNGLNLLGVSSYWQQIVKGAIILLAVLLDRLRRRRRAR 322
TM_PBP1_transp_AraH_like cd06579
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the ...
 50-308 1.75e-83

Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.


Pssm-ID: 119321 [Multi-domain]  Cd Length: 263  Bit Score: 253.49  E-value: 1.75e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  50 AVTTILAFGQTILIISGMLDLSQGSVLALSGVFAISAYKATG-SLVVAVLVGIITGVVCNFINALMISTFKAPPFIATLA 128
Cdd:cd06579    2 AVLGILALGMTLVIITGGIDLSVGSVAALSAVVAALLLVNAGlPIPLAILAALAVGALIGLLNGLLVAYLRIPPFIVTLG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 129 MLTMARGVALLYTKGQNILQLDKF--VVFGQGSVGVIPIPIIFLVALAIVTWYILKHTRIGRSLYAVGGNEEASVASGIN 206
Cdd:cd06579   82 TMFILRGLALLITGGRPISGLPPLfsFFLGGGLILGIPVPVLIALAVALVAWFLLRRTRFGRYLYAVGGNPEAARLSGIN 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 207 VHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTAAIIGGTSFSGGVGTATGTLAGAFIVGFLDNIMNLT 286
Cdd:cd06579  162 VRRVKILAYVLSGLLAGLAGILLAARLGSAQPTAGNGYELDAIAAVVLGGTSLTGGRGSVLGTLLGALLLGVLNNGLNLL 241

                        250       260
                 ....*....|....*....|..
gi 523697111 287 SVDSYMQQIVRGAIIALAVIYD 308
Cdd:cd06579  242 GVSSFWQQIVKGAILLLAVALD 263
rbsC PRK09512
ribose ABC transporter permease protein; Reviewed
 22-312 1.53e-74

ribose ABC transporter permease protein; Reviewed


Pssm-ID: 181922 [Multi-domain]  Cd Length: 320  Bit Score: 232.69  E-value: 1.53e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  22 LFVLFIICSLANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSGVFAISAYKATGSLVVAVLVGI 101
Cdd:PRK09512  25 LLVLIAIVSTLSPNFFTVNNLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVPAAL 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 102 ITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKGQNIL-----QLDKFVVFGQGSVGVIPIPIIFLVALAIV 176
Cdd:PRK09512 105 ALGAAIGAVTGVIVAKGKVQAFIATLVMMLLLRGVTMVYTDGSPINtgftdNADLFGWFGIGRPLGIPTPVWIMAIVFLA 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 177 TWYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTAAIIGG 256
Cdd:PRK09512 185 AWYMLHHTRLGRYIYALGGNEAATRLSGINVNKVKIIVYALCGLLAALAGIIEVARLSSAQPTAGTGYELDAIAAVVLGG 264

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 523697111 257 TSFSGGVGTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVIYDIQSK 312
Cdd:PRK09512 265 TSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ 320
COG4158 COG4158
Predicted ABC-type sugar transport system, permease component [General function prediction ...
 18-308 2.79e-70

Predicted ABC-type sugar transport system, permease component [General function prediction only];


Pssm-ID: 443324  Cd Length: 334  Bit Score: 222.11  E-value: 2.79e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  18 IFMVLFVLFIICSLANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSGVFAISAYKATGSLVVAV 97
Cdd:COG4158   32 MLPVLILLCIGFELLTPNFLTVQNLSNIARQASINIVLAAGMTFVILTGGIDLSVGSILAASAVVAVLVSLLPGLGLLGI 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  98 LVGIITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKGQNILQLD-KFVVFGQGSVGVIPIPIIFLVALAIV 176
Cdd:COG4158  112 PAALLVGLLFGLINGLLIAFLKLPPFIVTLGSLTALRGAARLLANGTTVFNPDlPFAWIGNGYLLGIPWLVVIALAVVLA 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 177 TWYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGA-VGYEFTALTAAIIG 255
Cdd:COG4158  192 SWFILRRTVLGVHIYAVGGNAQAARLTGIKVWRVLLFVYAVSGLLAGLGGVMSAARLYAANGLQLgQGYELDAIAAVILG 271

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 523697111 256 GTSFSGGVGTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVIYD 308
Cdd:COG4158  272 GTSFVGGIGSIWGTLIGALIIAVLNNGLILLGVSDFWQFIIKGLVIIIAVALD 324
XylH COG4214
ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism];
14-315 1.73e-68

ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443360 [Multi-domain]  Cd Length: 393  Bit Score: 219.22  E-value: 1.73e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  14 KKYSIFMVLFVLFIICSLAN-PNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSG-VFAISAYKATG 91
Cdd:COG4214   23 RSLGMIIALVVIWIVFQILTgGTFLTPRNLSNLLLQNSYIGILAIGMVLVILLGHIDLSVGSVSGFVGaVAAVLMVNWGL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  92 SLVVAVLVGIITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKGQNILQLDK-FVVFGQGS----------- 159
Cdd:COG4214  103 PWWLAILAALLVGALIGAWQGFWVAYVGIPSFIVTLAGMLAFRGLTLLVLGGGTIAPFDPtFQAIGNGFlpdilgtlswv 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 160 VGV-----------------------------------------------------IPIPIIFLVALAIVTWYILKHTRI 186
Cdd:COG4214  183 LGAvavaayvalqlrsrrrrrryglpveplwlfvlklallavlilgavyllnsyrgIPIVVLILLVLVVVYTFVLTRTVF 262

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 187 GRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTAAIIGGTSFSGGVGTA 266
Cdd:COG4214  263 GRHIYAVGGNPEAARLSGINVRRVTFSVFVNMGVLAALAGIVFAARLNSATPSAGTGFELDAIAAAVIGGTSLFGGVGTV 342

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 523697111 267 TGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVIYDIQSKNRR 315
Cdd:COG4214  343 YGAVIGALVMGSLNNGMSLLGVDSDWQQIVKGLVLLLAVAFDVLSRRRR 391
araH PRK11285
L-arabinose transporter permease protein; Provisional
 15-318 5.62e-63

L-arabinose transporter permease protein; Provisional


Pssm-ID: 183076 [Multi-domain]  Cd Length: 333  Bit Score: 203.37  E-value: 5.62e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  15 KYSIFMVLFVLFIICSLANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSGVFAISAYKATGSLV 94
Cdd:PRK11285  29 QYGMLVVFAVLFIACSLFVPNFASFINMKGLGLAISMIGMVACTMLFCLASGDFDLSVASVVAFAGVVTAVVINATESLW 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  95 VAVLVGIITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKGQNI-LQLDKFVVFGQGSVGVIPIPIIFLVAL 173
Cdd:PRK11285 109 LGVAAGLLLGAAVGLVNGFVIARLKINALITTLATMQIVRGLAYIISDGKAVgISDERFFALGYANFFGVPAPIWLTVAC 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 174 AIVTWYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTAAI 253
Cdd:PRK11285 189 FVVFGFLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLQGLVSALAGVILASRMTSGQPMTSIGFELIVISACV 268

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 523697111 254 IGGTSFSGGVGTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVIYDiQSKNRRTKS 318
Cdd:PRK11285 269 LGGVSLKGGIAKISGVVAGVLILGTVENAMNLLNISPFYQYVVRGLILLAAVLFD-RYKQRAKRT 332
PRK09699 PRK09699
D-allose ABC transporter permease;
6-308 6.59e-57

D-allose ABC transporter permease;


Pssm-ID: 182035 [Multi-domain]  Cd Length: 312  Bit Score: 186.90  E-value: 6.59e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111   6 NNLWNtakkKYSIFMVLFVLFIICSLANPN-FLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSGVFAI 84
Cdd:PRK09699   6 ALFWD----KYGTFFILAIIVAIFGSLSPEyFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGAILALSGMVTA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  85 SAYKATGSLVVAVLVG-IITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKGQNILQLD-KFVVFGQGSVGV 162
Cdd:PRK09699  82 KLMLAGVDPFLAALIGgVLVGGALGAINGCLVNWTGLHPFIITLGTNAIFRGITLVISDANSVYGFSfDFVNFFAASVIG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 163 IPIPIIFLVALAIVTWYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAV 242
Cdd:PRK09699 162 IPVPVIFSLIVALILWFLTTRMRLGRNIYALGGNKNSAFYSGIDVKFHILVVFIISGVCAGLAGVVSTARLGAAEPLAGM 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 523697111 243 GYEFTALTAAIIGGTSFSGGVGTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVIYD 308
Cdd:PRK09699 242 GFETYAIASAIIGGTSFFGGKGRIFSVVIGGLIIGTINNGLNILQVQTYYQLVVMGGLIIAAVALD 307
mglC PRK09478
galactose/methyl galactoside ABC transporter permease MglC;
1-310 1.01e-52

galactose/methyl galactoside ABC transporter permease MglC;


Pssm-ID: 181892 [Multi-domain]  Cd Length: 336  Bit Score: 176.80  E-value: 1.01e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111   1 MDLRSNNLWNTAKKKYSIFMVLFVLFIICSLANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSG 80
Cdd:PRK09478   1 MSALNKKSFLTYLKEGGIYVVLLVLLAIIIIQDPTFLSLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  81 VFAIS-------AYK-----ATGSLVVAVLVGIITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTK---GQN 145
Cdd:PRK09478  81 VVAATllqsmdnANKvfpelATMPIALVILIVCAIGAVIGLINGLIIAYLNVTPFIATLGTMIIVYGINSLYYDfvgASP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 146 ILQLD-KFVVFGQGSVGV----IPIPIIFLVALAIVTWYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGI 220
Cdd:PRK09478 161 ISGFDsGFSTFAQGFVALgsfrLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVPLNLLMIYALSGV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 221 FVGLAGVLFMSRVNAGLPNGAVGYEFTALTAAIIGGTSFSGGVGTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAI 300
Cdd:PRK09478 241 FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAI 320

                        330
                 ....*....|
gi 523697111 301 IALAVIYDIQ 310
Cdd:PRK09478 321 IIFAVALDSL 330
GguB NF040906
sugar ABC transporter permease;
14-314 3.23e-45

sugar ABC transporter permease;


Pssm-ID: 468841 [Multi-domain]  Cd Length: 375  Bit Score: 158.01  E-value: 3.23e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  14 KKYSIFMVLFVLFIICS-LANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSG-VFAISAYKATG 91
Cdd:NF040906   3 RQYGMLIALVAIVVLFQiLTGGILLRPLNVTNLILQNSYILILAIGMLLVIIAGHIDLSVGSVVAFVGaVAAVLMVNWGM 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  92 SLVVAVLVGIITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKGQNI------------------------- 146
Cdd:NF040906  83 PWWLAVLLCLLVGALIGAWQGFWVAYVGIPAFIVTLAGMLVFRGLTLVVLGGQSIgpfpdgfqkissgflpdlfggtglh 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 147 -----------------------------LQLDKFVVFGQGSVGV----------------IPIPIIFLVALAIVTWYIL 181
Cdd:NF040906 163 lltlllgvlaaaalvwsqlrgrrrrikygLEVEPMALFIAKLVLIaaailfftyllasyrgLPNVLIILGVLILVYSFVT 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 182 KHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTAAIIGGTSFSG 261
Cdd:NF040906 243 NRTVIGRHIYAVGGNEKAAKLSGIKTKRVTFLVFVNMGVLAALAGLVFAARLNSATPKAGNGFELDAIAACFIGGASASG 322

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 523697111 262 GVGTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVIYDIQSKNR 314
Cdd:NF040906 323 GVGTVVGAIIGALVMGVLNNGMSILGIGIDWQQVIKGLVLLAAVAFDVYNKRK 375
PRK11618 PRK11618
inner membrane ABC transporter permease protein YjfF; Provisional
 20-277 1.03e-36

inner membrane ABC transporter permease protein YjfF; Provisional


Pssm-ID: 183235 [Multi-domain]  Cd Length: 317  Bit Score: 134.31  E-value: 1.03e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  20 MVLFVLFIICSLANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSGVFAISAYKATG--SLVVAV 97
Cdd:PRK11618  13 GVFVLGYLFCLVQFPGFASTRVICNLLTDNAFLGIVAVGMTFVILSGGIDLSVGSVIAFTGVFLAKLIGDYGwsPLLAFP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  98 LVGIITGVVCNFINALmISTFKAPPFIATLAMLTMARGVALLYTKgQNI---------LQLDKFVVFGQGSVGVIPIPII 168
Cdd:PRK11618  93 LVLVMGAAFGAFMGAL-IHYLKLPAFIVTLAGMFLARGVSFLVSE-ESIpinhpfydtLSSLAWKLPGGGRLSAMALIML 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 169 FLVALAIvtwYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTA 248
Cdd:PRK11618 171 AVVAIGI---FLAHRTRFGNNVYAIGGNATSANLMGIPVRRTTIRIYMLSGFLATLAGIVFSLYTSAGYALAAVGVELDA 247

                        250       260
                 ....*....|....*....|....*....
gi 523697111 249 LTAAIIGGTSFSGGVGTATGTLAGAFIVG 277
Cdd:PRK11618 248 IAAVVIGGTLLTGGVGTVLGTLFGVLIQG 276
PRK15432 PRK15432
autoinducer 2 ABC transporter permease LsrC; Provisional
 17-308 9.32e-35

autoinducer 2 ABC transporter permease LsrC; Provisional


Pssm-ID: 185330 [Multi-domain]  Cd Length: 344  Bit Score: 129.85  E-value: 9.32e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  17 SIFMVLFVLFIICSLANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSGVFAISAYKATGSLVVA 96
Cdd:PRK15432  12 TALLAIVLLFVLLGFLDRQYLSLQTLTMVFSSAQILILLAIGATLVMLTRNIDVSVGSITGLCAVLVGMLLNAGYSLPVA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  97 VLVGIITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKG-------QNILQLDKFVVFGQGSVGVIpipiif 169
Cdd:PRK15432  92 CLATLLLGLLAGFFNGVLVAWLRIPAIVATLGTLGLYRGIMLLWTGGkwieglpAELKQLSAPILLGISPIGWL------ 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 170 LVALAIVTWYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAgLPNG-AVGYEFTA 248
Cdd:PRK15432 166 TLILILAMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGF-IPNQtGTGLEMKA 244

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 249 LTAAIIGGTSFSGGVGTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVIYD 308
Cdd:PRK15432 245 IAACVLGGISLLGGSGTIIGAVLGAYFLTQIDSVLVLLRIPAWWNDFIAGLVLLGVLVFD 304
BPD_transp_2 pfam02653
Branched-chain amino acid transport system / permease component; This is a large family mainly ...
 41-305 4.94e-29

Branched-chain amino acid transport system / permease component; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease and a ribose transport system.


Pssm-ID: 396977 [Multi-domain]  Cd Length: 269  Bit Score: 112.74  E-value: 4.94e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111   41 NLTNISRQLAVTTILAFGQTILI-ISGMLDLSQGSVLALSGVFAISAYKATGSLV-VAVLVGIITGVVCNFINALMISTF 118
Cdd:pfam02653   1 NILNILTLASIYAIAALGLTLIYgIAGVINLGHGGFMMLGAYVAAMLLNLLGPGLwLALPVGILVGAAVGLLIGILTLRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  119 KAPPFIATLAMLTMARGVALLY----TKGQNILQLDKFVVFGQG---SVGVIPIPIIFLVALAIVtWYILKHTRIGRSLY 191
Cdd:pfam02653  81 KINEVIITLLLNLAALGLALFLvtgiLGGEGGTSGITGPSGFPGaflSFAFAFIFLLALLLVLAL-WLLLYRTKFGRALR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  192 AVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGA-VGYEFTALTAAIIGGTsfsggvGTATGTL 270
Cdd:pfam02653 160 AVGENEEAARAAGINVKKLKLLTFVISGALAGLAGALLALYTGVVPPSNFgVGLGLDAIAAVVLGGA------GSPIGVV 233

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 523697111  271 AGAFIVGFLDNIM-NLTSVDSYMQQIVRGAIIALAV 305
Cdd:pfam02653 234 IGSLIIGLVQSLGlGALGSPPELSLLVLGALLILVL 269
TM_PBP1_branched-chain-AA_like cd06574
Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette ...
 54-305 8.49e-27

Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of monosaccharides including ribose, galactose, and arabinose. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. This group includes Escherichia coli LivM and LivH, two TMs which heterodimerize to form the translocation pathway of the E. coli branched-chain AA LIV-1/LS transporter. This transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) and LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine. Included in this group are proteins from transport systems that contain a single TM which homodimerizes to generate the transmembrane pore; for example E. coli RbsC, AlsC, and MglC, the TMs of the high affinity ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also to be involved in low affinity ribose transport.


Pssm-ID: 119320 [Multi-domain]  Cd Length: 266  Bit Score: 106.59  E-value: 8.49e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  54 ILAFGQTILI-ISGMLDLSQGSVLALSGVFAISAYKATGSLVVAVLVGIITGVVCNFINALMISTFKAPPFIATLAMLTM 132
Cdd:cd06574    6 ILALGVYIVFrILGFPDLTVDGSFPLGAAVAAILIVAGYNPWLALIAAILAGAAAGLVTGFLHTRLKINGLLAGILIMIG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 133 ARGVALLYTKGQNILQLDK------FVVFGQGSVGVIPIPIIFLVALAIVTWYILKHTRIGRSLYAVGGNEEASVASGIN 206
Cdd:cd06574   86 LYSINLRIMGGPNIPLGTRdtllglLLLFGISGTLSIPVVLLLIVLLVLFLVIWFLRTKLGLAMRATGDNPDMARSLGIN 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 207 VHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTAAIIGGTSFSGGVGTA--TGTLAGAFIVGFLDNIMN 284
Cdd:cd06574  166 VDRTRILGLVISNALAALGGALYAQYQGFADVNMGIGTGVIGLAAVIIGGAIVGRRTIKAsiLGVIIGAILYRIALALAL 245

                        250       260
                 ....*....|....*....|.
gi 523697111 285 LTSVDSYMQQIVRGAIIALAV 305
Cdd:cd06574  246 GSGLIPSDLKLITAGVIVLVL 266
PRK15038 PRK15038
autoinducer 2 ABC transporter permease LsrD;
31-306 2.96e-22

autoinducer 2 ABC transporter permease LsrD;


Pssm-ID: 184998  Cd Length: 330  Bit Score: 95.28  E-value: 2.96e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  31 LANPNFLTTSNLTNISRQLAVTTILAFGQTILIISGMLDLSQGSVLALSGVFAISAYKATGSLVVAVLVGIITGVVCNFI 110
Cdd:PRK15038  24 LINPRMLDINVLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLFQSGVPMPLAILLTLLLGALCGLI 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 111 NALMISTFKAPPFIATLAMLTMARGVALLYTKGQNILQLD-------KFVVFGQGSVGVIPIPIIFLVALAIVTWYILKH 183
Cdd:PRK15038 104 NAGLIIYTGVNPLVITLGTLYLFGGSALLLSGMAGATGYEgiggfpmAFTDFANLDVLGLPVPLIIFLICLLVFWLLMHR 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 184 TRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNGAVGYEFTALTAAIIGGTSFSGGV 263
Cdd:PRK15038 184 THAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMTGLASAIAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGS 263

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 523697111 264 GTATGTLAGAFIVGFLDNIMNLTSVDSYMQQIVRGAIIALAVI 306
Cdd:PRK15038 264 GSIIGTALAVLLVGYLQQGLQMAGVPNQISSALSGALLIVVVV 306
NupQ COG1079
ABC-type guanosine uptake system NupNOPQ, permease subunit NupQ [Nucleotide transport and ...
 65-282 1.21e-21

ABC-type guanosine uptake system NupNOPQ, permease subunit NupQ [Nucleotide transport and metabolism];


Pssm-ID: 440697 [Multi-domain]  Cd Length: 309  Bit Score: 93.21  E-value: 1.21e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  65 SGMLDLSQGSVLALSGVFAISAYKATGSLVVAVLVGIITGVVCNFINALMISTFKAPPFIATLAMLTMARGVA-----LL 139
Cdd:COG1079   34 AGVLNIGLEGMMLMGAFAGFAVAYLTGSPWLGLLAAALAGALLALLHAFLTITLRANQIVSGLALNLLALGLTaflgrLL 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 140 YTKGQNILQLDKFVVFGQGSVGVIPI--PIIF--------LVALAIVTWYILKHTRIGRSLYAVGGNEEASVASGINVHR 209
Cdd:COG1079  114 FGQGGQTPSIPGLPPIPIPGLSDIPVlgPLLFgqsplvylALLLVPLVWWVLYRTRFGLRLRAVGENPAAADALGINVYR 193

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 523697111 210 VKYTAFIINGIFVGLAGVLF-MSRVNAGLPNGAVGYEFTALTAAIIGGtsfsggvGTATGTLAGAFIVGFLDNI 282
Cdd:COG1079  194 IRYLAVLIGGALAGLGGAYLsLGYVGSFTEGMTAGRGFIALAAVIFGR-------WRPLGALLAALLFGFADAL 260
TM_PBP1_LivM_like cd06581
Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two ...
 50-307 6.42e-21

Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.


Pssm-ID: 119323 [Multi-domain]  Cd Length: 268  Bit Score: 90.58  E-value: 6.42e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  50 AVTTILAFGQTILI-ISGMLDLSQGSVLALSG-VFAISAYKATGSLVVAVLVGIITGVVCNFINALMISTFKAPPF-IAT 126
Cdd:cd06581    2 LIYAILALGLNLLLgYAGQLSLGHAAFFGIGAyTAALLATRLGLPFWLALLAAGLVAALVGLLLGLPALRLRGVYFaIAT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 127 LAMLTMARGVAL---LYTKGQN-ILQLDKFVVFGQGSVGVIPIPIIFLVALAIVTW--YILKHTRIGRSLYAVGGNEEAS 200
Cdd:cd06581   82 LAFAEIVRLLALnwsSLTGGSNgLSGIPPPLLGGLLLSSPLAFYYLVLAVLLLVLLllRRLVRSPFGRALRAIRENEVAA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 201 VASGINVHRVKYTAFIINGIFVGLAGVLFMSRVN-AGLPNGAVGYEFTALTAAIIggtsfsGGVGTATGTLAGAFIVGFL 279
Cdd:cd06581  162 EALGINVTRYKLLAFALSAALAGLAGALYAHYLGfVSPESFGFALSIELLLMVVL------GGLGSLLGPVLGAALLVLL 235

                        250       260
                 ....*....|....*....|....*...
gi 523697111 280 DNImnLTSVDSYMQQIVRGAIIALAVIY 307
Cdd:cd06581  236 PEL--LRSLGPGLRLLVFGLLLILVVLF 261
TM_PBP1_transp_TpRbsC_like cd06580
Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. ...
 89-304 1.42e-20

Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters, which are mainly involved in the uptake of branched-chain amino acids (AAs) or in the uptake of monosaccharides including ribose, galactose, and arabinose, and which generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction.


Pssm-ID: 119322 [Multi-domain]  Cd Length: 234  Bit Score: 88.65  E-value: 1.42e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  89 ATGSLVVAVLVGIITGVVCNFINALMISTFKAPPFIATLAMLTMArgvallytkgqnilqldkfvvfgqgsVGVIPIPII 168
Cdd:cd06580   46 ATGSLPLGLLAAALAGALWALLPALLKAKLGVNEVISGLMLNYIA--------------------------LGLTSYLLL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 169 FLVALAIVTWYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAG-VLFMSRVNAGLPNGAVGYEFT 247
Cdd:cd06580  100 LALLLVILVWLLLYRTRFGLRLRAVGENPRAARYAGINVKRVRLLAMLISGALAGLAGaYLVLGVQGRFTEGMSAGYGFI 179

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 523697111 248 ALTAAIIGGtsfsggvGTATGTLAGAFIVGFLDNIMN----LTSVDSYMQQIVRGAIIALA 304
Cdd:cd06580  180 AIAVALLGR-------WNPLGILLAALLFGALEAGGIalqrSGGVPSELVQVLPGIIVLFV 233
LivH COG0559
Branched-chain amino acid ABC-type transport system, permease component [Amino acid transport ...
 64-283 5.09e-20

Branched-chain amino acid ABC-type transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440325 [Multi-domain]  Cd Length: 290  Bit Score: 88.20  E-value: 5.09e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  64 ISGMLDLSQGSVLALSGVFAISAYKATG-----SLVVAVLVGIITGVVcnfINALMISTF-KAPP---FIATLAMLTMAR 134
Cdd:COG0559   31 VMGVINFAHGEFVMLGAYVAYTLATLLGlplwlALLLAVLVAALLGVL---LERLVIRPLrGAPPlalLLATIGLSLVLQ 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 135 GVALLYTKGQNI---LQLDKFVVFGQGSVGVIPIPIIFL-VALAIVTWYILKHTRIGRSLYAVGGNEEASVASGINVHRV 210
Cdd:COG0559  108 GLVLLIFGADPRsfpALLSGSVELGGVSIPAYRLFIIVVaLVLLAALWLFLRRTRLGLAMRAVAQNREAARLMGINVDRV 187

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 523697111 211 KYTAFIINGIFVGLAGVLFMSRVNAGlPNGAVGYEFTALTAAIIggtsfsGGVGTATGTLAGAFIVGFLDNIM 283
Cdd:COG0559  188 IALTFALGAALAGLAGVLLAPIYSVS-PTMGFLLGLKAFAAVVL------GGLGSIPGAVVGGLLLGLAESLG 253
LivM COG4177
ABC-type branched-chain amino acid transport system, permease component [Amino acid transport ...
 48-307 6.99e-20

ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443336 [Multi-domain]  Cd Length: 285  Bit Score: 87.83  E-value: 6.99e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  48 QLAVTTILAFGQTILI-ISGMLDLSQGSVLALSG-VFAISAYKATGSLVVAVLVGIITGVVCNFINALMISTFKAPPF-I 124
Cdd:COG4177   10 LILIYAILALGLNLLLgYTGLLSLGHAAFFGIGAyAAALLTTHLGLPFWLALLLAGLVAALLGLLIGLPALRLRGDYLaI 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 125 ATLAMLTMARGVAL---LYTKGQN-ILQLDKFVVFGQGSVGVIPIPIIFLVALAIVTW--YILKHTRIGRSLYAVGGNEE 198
Cdd:COG4177   90 ATLAFAEIVRLLALnleSLTGGADgLSGIPRPTLFGLDLGSPLAFYYLVLALLVLVLLllRRLVRSRFGRALRAIRENEI 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 199 ASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGLPNG-AVGYEFTALTAAIIggtsfsGGVGTATGTLAGAFIVG 277
Cdd:COG4177  170 AAEALGINVTRYKLLAFVLSAALAGLAGALYAHYVGFVSPESfSFLLSIEILLMVVL------GGLGSLLGPVLGAVLLV 243

                        250       260       270
                 ....*....|....*....|....*....|
gi 523697111 278 FLDNImnLTSVDSYmQQIVRGAIIALAVIY 307
Cdd:COG4177  244 LLPEL--LRSLPEY-RLLIFGLLLILVVLF 270
TM_PBP1_LivH_like cd06582
Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two ...
 54-282 1.94e-18

Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.


Pssm-ID: 119324 [Multi-domain]  Cd Length: 272  Bit Score: 83.63  E-value: 1.94e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  54 ILAFGQT-ILIISGMLDLSQGSVLALSGVFAISAYKATG-----SLVVAVLVGIITGVVCNFInaLMISTFKAPPF---I 124
Cdd:cd06582   10 LIALGLTlIFGVTGVINFAHGEFYMLGAYVAYTLLVALGlpfwlALLLALLVAALLGVLLERL--VLRPLRGAPLLtllI 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 125 ATLAMLTMARGVALLYtkGQNILQLDKFVVFGQGSVGVIPIP----IIFLVALAIV--TWYILKHTRIGRSLYAVGGNEE 198
Cdd:cd06582   88 TFGGLLILLQGLLLIF--GGDPRVPPPPLLSGSVELGGVTIPpyrlFIIAVALVLLaaLYLFLRRTRLGRAIRAVAQNPE 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 199 ASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGlPNGAVGYEFTALTAAIIggtsfsGGVGTATGTLAGAFIVGF 278
Cdd:cd06582  166 AARLLGINVRRVFALTFALGAALAGLAGVLLAPITGVS-PTMGLLLLLKAFAAVVL------GGLGSIPGAVVGGLLLGL 238


                 ....
gi 523697111 279 LDNI 282
Cdd:cd06582  239 AESL 242
NupP COG4603
ABC-type guanosine uptake system NupNOPQ, permease component NupP [Nucleotide transport and ...
 163-301 1.29e-13

ABC-type guanosine uptake system NupNOPQ, permease component NupP [Nucleotide transport and metabolism];


Pssm-ID: 443653 [Multi-domain]  Cd Length: 356  Bit Score: 70.92  E-value: 1.29e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 163 IPIPIIFLVALAIVTWYILKHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVNAGL-PNGA 241
Cdd:COG4603  196 LHLGLLIALLAAVLVWVLLNRTTLGYELRAVGLNPRAARYAGINVKRLIVLAMLISGALAGLAGAVEVLGVQGRLtPGFS 275

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 523697111 242 VGYEFTALTAAIIGGtsfsggvGTATGTLAGAFIVGFL----DNIMNLTSVDSYMQQIVRGAII 301
Cdd:COG4603  276 PGYGFTGIAVALLGR-------NNPLGIILAALLFGALyvggDAMQRALGVPSEIVDVIQGLII 332
COG4120 COG4120
ABC-type uncharacterized transport system, permease component [General function prediction ...
 94-229 1.15e-07

ABC-type uncharacterized transport system, permease component [General function prediction only];


Pssm-ID: 443296  Cd Length: 296  Bit Score: 52.43  E-value: 1.15e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  94 VVAVLVGIITGVVCNFINALMISTFKAPPFIATLAMLTMARGVALLYTKGQNILQLDKFVVFGQ-------GSVGVIPIP 166
Cdd:COG4120   59 FLATLAAFLAGALAGLVTGLLHTKLKIPPLLAGILTMTALYSINLRIMGKPNIPLLGEDTIFTLlpdlglpGDWAKLLVL 138

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 523697111 167 IIFLVALAIVTWYILkHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLF 229
Cdd:COG4120  139 LVIVLVIKLLLDWFL-KTELGLALRATGDNPQMARALGINTDRMKILGLALSNGLVALSGALV 200
livM PRK11301
leucine/isoleucine/valine transporter permease subunit; Provisional
 167-283 2.08e-04

leucine/isoleucine/valine transporter permease subunit; Provisional


Pssm-ID: 236896 [Multi-domain]  Cd Length: 419  Bit Score: 42.65  E-value: 2.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 167 IIFL--VALAIVTWYILKHTR-----IGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRvnaglpN 239
Cdd:PRK11301 261 VIFLylVALLLVVLTLFVINRllrmpLGRAWEALREDEIACRSLGLNPTRIKLSAFTIGAAFAGFAGTFFAAR------Q 334

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 523697111 240 GAVGYE-FTALTAAIIGGTSFSGGVGTATGTLAGAFIVGFLDNIM 283
Cdd:PRK11301 335 GFVSPEsFTFIESAFILAIVVLGGMGSQFGVILAAILLVVLPELM 379
PRK10740 PRK10740
high-affinity branched-chain amino acid ABC transporter permease LivH;
54-277 3.08e-03

high-affinity branched-chain amino acid ABC transporter permease LivH;


Pssm-ID: 182689 [Multi-domain]  Cd Length: 308  Bit Score: 38.75  E-value: 3.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111  54 ILAFGQTILI-ISGMLDLSQGSVlalsgvFAISAYKATGSLVVAVLVGIITG---VVCNFINALMISTFKAPPF--IATL 127
Cdd:PRK10740  24 LIAIGYTMVYgIIGMINFAHGEV------YMIGSYVSFMIIAALMMMGIDTSwllVAAGFVGAIVIASAYGWSIerVAYR 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 128 AMLTMARGVALLYTKGQNILqLDKFVVFGQGSVGV--------------------------IPIPIIFLVALAIVTWYIl 181
Cdd:PRK10740  98 PVRNSKRLIALISAIGMSIF-LQNYVSLTEGSRDValpslfngqwvvghsenfsasittmqAVIWIVTFLAMLALTIFI- 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523697111 182 KHTRIGRSLYAVGGNEEASVASGINVHRVKYTAFIINGIFVGLAGVLFMSRVnaGLPNGAVGY--EFTALTAAIIggtsf 259
Cdd:PRK10740 176 RYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAVAGVLLGQFY--GVINPYIGFmaGMKAFTAAVL----- 248

                        250
                 ....*....|....*...
gi 523697111 260 sGGVGTATGTLAGAFIVG 277
Cdd:PRK10740 249 -GGIGSIPGAMIGGLILG 265
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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