|
Name |
Accession |
Description |
Interval |
E-value |
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
6-632 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 752.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 6 SPEGQLAQAIPGFKPREPQRQMAHAVARAIDTAQPLVVEAGTGTGKTYAYLAPALRA----KKKVIISTGSKALQDQLYS 81
Cdd:COG1199 1 ADDGLLALAFPGFEPRPGQREMAEAVARALAEGRHLLIEAGTGTGKTLAYLVPALLAaretGKKVVISTATKALQEQLVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 82 RDLPTVANALKYKGRLALLKGRSNYLCLERLEQqALAGGDLPVQTLSDVIILRAWANQTEEGDISTCASvPEDSPAWPLV 161
Cdd:COG1199 81 KDLPLLRKALGLPLRVALLKGRSNYLCLRRLEQ-ALQEGDDLDDEELLLARILAWASETWTGDRDELPL-PEDDELWRQV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 162 TSTNDNCLGSDCPLYKDCFVVKARKTAMDADVVVVNHHLFLADMVVKDsgfgELIPEADVMIFDEAHQLPDIASQYFGQS 241
Cdd:COG1199 159 TSDADNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALGE----ELLPEDDVLIIDEAHNLPDRARDMFSAE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 242 LSSRQLQDLAKDFTIAYRTelKDTQQLQKCADRLAQSAQDFRLQLGE-PGYRGNLRELLAD-KNIQRALLLLDDALELCY 319
Cdd:COG1199 235 LSSRSLLRLLRELRKLGLR--PGLKKLLDLLERLREALDDLFLALEEeEELRLALGELPDEpEELLEALDALRDALEALA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 320 DVAKLSLGRSALLDAAFERATLYRARLKR-LKEINQPGFSYWYECTSRHFTLALTPLTVADKFKEVMAQKPGSWIFTSAT 398
Cdd:COG1199 313 EALEEELERLAELDALLERLEELLFALARfLRIAEDEGYVRWLEREGGDVRLHAAPLDPADLLRELLFSRARSVVLTSAT 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 399 LSVNDDLHHFTGRLGIEQ-AESLLLPSPFDYETQALLCVPRNLPLPNQ-PGAARLLAAMLRPMIEANNGRCFMLCTSHAM 476
Cdd:COG1199 393 LSVGGPFDYFARRLGLDEdARTLSLPSPFDYENQALLYVPRDLPRPSDrDGYLEAIAEAIAELLEASGGNTLVLFTSYRA 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 477 MRDLAEQFRATMTLPVLLQGETSKGQLLQQFVSAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMED 556
Cdd:COG1199 473 LEQVAELLRERLDIPVLVQGDGSREALLERFREGGNSVLVGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREA 552
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 527036687 557 CRLRGGDPFDEVQLPDAVITLKQGVGRLIRDTDDRGVLVICDNRLVMRPYGATFLASLPPAPRTRdIKRAVRFLAN 632
Cdd:COG1199 553 LEARGGNGFMYAYLPPAVIKLKQGAGRLIRSEEDRGVVVLLDRRLLTKRYGKRFLDSLPPFRRTR-PEELRAFLER 627
|
|
| PRK08074 |
PRK08074 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
8-618 |
2.26e-128 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain] Cd Length: 928 Bit Score: 400.87 E-value: 2.26e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 8 EGQLAQAIPGFKPREPQRQMAHAVARAIDTAQPLVVEAGTGTGKTYAYLAP----ALRAKKKVIISTGSKALQDQLYSRD 83
Cdd:PRK08074 246 EEKLSLAMPKYEKREGQQEMMKEVYTALRDSEHALIEAGTGTGKSLAYLLPaayfAKKKEEPVVISTYTIQLQQQLLEKD 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 84 LPTVANALKYKGRLALLKGRSNYLCLERLEQqALAGGDlpvqTLSDVIILRA----WANQTEEGDISTcASVPEdSPA-- 157
Cdd:PRK08074 326 IPLLQKIFPFPVEAALLKGRSHYLCLRKFEQ-ALQEED----DNYDVALTKAqllvWLTETETGDLDE-LNLPS-GGKll 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 158 WPLVTSTNDNCLGSDCPLYKDCFVVKARKTAMDADVVVVNHHLFLADMVVKDSgfgeLIPEADVMIFDEAHQLPDIASQY 237
Cdd:PRK08074 399 WNRIASDGESDGGKQSPWFSRCFYQRAKNRAKFADLVITNHALLLTDLTSEEP----LLPSYEHIIIDEAHHFEEAASRH 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 238 FGQSLSSRQLQ-------------DLAKDFTIAYRTELKDTQQLQKC----------ADRLAQSAQDF------RLQLGE 288
Cdd:PRK08074 475 LGEQFSYMSFQlllsrlgtleedgLLSKLAKLFKKSDQASRSSFRDLdeslkelkfeADELFQMLRSFvlkrkkQEQNGR 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 289 PGYRGNlRELLADKNIQRALLLLDDALELCYDV-AKLSLGRSALLD-----AAFERATL--------YRARLKRLKEINQ 354
Cdd:PRK08074 555 LIYRYN-TESEKGKLWDAITELANRLCYDLRDLlTLLEAQKKELQEkmeseSAFLTGEYahlidlleKMAQLLQLLFEED 633
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 355 PGFSYWYECTSRHFTLALT----PLTVADKF-KEVMAQKPgSWIFTSATLSVNDDLHHFTGRLGIE--QAESLLLPSPFD 427
Cdd:PRK08074 634 PDYVTWIEIDAKGAINATRlyaqPVEVAERLaDEFFAKKK-SVILTSATLTVNGSFDYIIERLGLEdfYPRTLQIPSPFS 712
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 428 YETQALLCVPRNLPL---PNQPGAARLLAAMLRPMIEANNGRCFMLCTSHAMMRDLAEQFRATMTLP--VLL-QGET--S 499
Cdd:PRK08074 713 YEEQAKLMIPTDMPPikdVPIEEYIEEVAAYIAKIAKATKGRMLVLFTSYEMLKKTYYNLKNEEELEgyVLLaQGVSsgS 792
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 500 KGQLLQQFVSAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFDEVQLPDAVITLKQ 579
Cdd:PRK08074 793 RARLTKQFQQFDKAILLGTSSFWEGIDIPGDELSCLVIVRLPFAPPDQPVMEAKSEWAKEQGENPFQELSLPQAVLRFKQ 872
|
650 660 670
....*....|....*....|....*....|....*....
gi 527036687 580 GVGRLIRDTDDRGVLVICDNRLVMRPYGATFLASLPPAP 618
Cdd:PRK08074 873 GFGRLIRTETDRGTVFVLDRRLTTTSYGKYFLESLPTVP 911
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
17-615 |
1.00e-86 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 288.63 E-value: 1.00e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 17 GFKPREPQRQMAHAVARAIDTAQPLVVEAGTGTGKTYAYLAPAL---RAKKKVIISTGSKALQDQLYSRDLPTVANALKY 93
Cdd:TIGR01407 243 GLEYRPEQLKLAELVLDQLTHSEKSLIEAPTGTGKTLGYLLPALyyaITEKPVVISTNTKVLQSQLLEKDIPLLNEILNF 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 94 KGRLALLKGRSNYLCLERLEQqALAGGdlpvQTLSDVIILRA----WANQTEEGDISTCASVPEDSPAWPLVTStnDNCL 169
Cdd:TIGR01407 323 KINAALIKGKSNYLSLGKFSQ-ILKDN----TDNYEFNIFKMqvlvWLTETETGDLDELNLKGGNKMFFAQVRH--DGNL 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 170 GSDCPLYKDCFVVKARKTAMDADVVVVNHHLFLADMVVKDsgfgELIPEADVMIFDEAHQLPDIASQYFGQSLSSRQLQD 249
Cdd:TIGR01407 396 SKKDLFYEVDFYNRAQKNAEQAQILITNHAYLITRLVDNP----ELFPSFRDLIIDEAHHLPDIAENQLQEELDYADIKY 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 250 LAKDFTIAyrtelkDTQQLQKcadRLAQSAQDFRLQLG---EPGYRGNLRELLADKNIQRALlllddalelcyDVAKLSL 326
Cdd:TIGR01407 472 QIDLIGKG------ENEQLLK---RIQQLEKQEILEKLfdfETKDILKDLQAILDKLNKLLQ-----------IFSELSH 531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 327 grsALLDAAFERATLYRARLKRLKEINQPGFSYWYEC----TSRHFTLALTPLTVADKFKEVMAQKPGSWIFTSATLSVN 402
Cdd:TIGR01407 532 ---KTVDQLRKFDLALKDDFKNIEQSLKEGHTSWISIenlqQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSATLKFS 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 403 DDLHHFTGRLGIEQAE-SLLLPSPFDYETQALLCVPRNLPL---PNQPGAARLLAAMLRPMIEANNGRCFMLCTSHAMMR 478
Cdd:TIGR01407 609 HSFESFPQLLGLTDVHfNTIEPTPLNYAENQRVLIPTDAPAiqnKSLEEYAQEIASYIIEITAITSPKILVLFTSYEMLH 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 479 DLAEQFRATMT---LPVLLQGET-SKGQLLQQFVSAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARM 554
Cdd:TIGR01407 689 MVYDMLNELPEfegYEVLAQGINgSRAKIKKRFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANPKHPLTKKYW 768
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 527036687 555 EDCRLRGGDPFDEVQLPDAVITLKQGVGRLIRDTDDRGVLVICDNRLVMRPYGATFLASLP 615
Cdd:TIGR01407 769 QKLEQEGKNPFYDYVLPMAIIRLRQALGRLIRRENDRGSIVILDRRLVGKRYGKRFEKSLP 829
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
459-616 |
6.81e-50 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 170.82 E-value: 6.81e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 459 MIEANNGRCFMLCTSHAMMRDLAEQFRATMT---LPVLLQ-GETSKGQLLQQFVSAG-NALLVATS--SFWEGVDVRGDT 531
Cdd:pfam13307 3 LLKVIPGGVLVFFPSYSYLEKVAERLKESGLekgIEIFVQpGEGSREKLLEEFKKKGkGAVLFGVCggSFSEGIDFPGDL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 532 LSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFDEVQLPDAVITLKQGVGRLIRDTDDRGVLVICDNRLVMRPYGATFL 611
Cdd:pfam13307 83 LRAVIIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRYGKLLP 162
|
....*
gi 527036687 612 ASLPP 616
Cdd:pfam13307 163 KWLPP 167
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
474-603 |
1.42e-41 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 147.43 E-value: 1.42e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 474 HAMMRDLAEQFRATMTL----PVLLQGETSKG--QLLQQFVSAGN---ALLVATSS--FWEGVDVRGDTLSLVIIDKLPF 542
Cdd:smart00491 1 YRYLEQVVEYWKENGILeinkPVFIEGKDSGEteELLEKYSAACEargALLLAVARgkVSEGIDFPDDLGRAVIIVGIPF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 527036687 543 TSPDDPLLKARMEDCRLRG-GDPFDEVQLPDAVITLKQGVGRLIRDTDDRGVLVICDNRLVM 603
Cdd:smart00491 81 PNPDSPILRARLEYLDEKGgIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
503-600 |
4.11e-10 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 58.77 E-value: 4.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 503 LLQQFVSAGNALL-VATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCR-------LRGGDPFDEvqlpDAV 574
Cdd:cd18788 57 YMERVVSRGALLLaVCRGKVSEGIDFSDDLGRAVIMVGIPYPNTKDPILKLKMDDLEylrdkglLTGEDWYTF----QAM 132
|
90 100
....*....|....*....|....*.
gi 527036687 575 ITLKQGVGRLIRDTDDRGVLVICDNR 600
Cdd:cd18788 133 RAVNQAIGRAIRHKNDYGAIVLLDKR 158
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
6-632 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 752.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 6 SPEGQLAQAIPGFKPREPQRQMAHAVARAIDTAQPLVVEAGTGTGKTYAYLAPALRA----KKKVIISTGSKALQDQLYS 81
Cdd:COG1199 1 ADDGLLALAFPGFEPRPGQREMAEAVARALAEGRHLLIEAGTGTGKTLAYLVPALLAaretGKKVVISTATKALQEQLVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 82 RDLPTVANALKYKGRLALLKGRSNYLCLERLEQqALAGGDLPVQTLSDVIILRAWANQTEEGDISTCASvPEDSPAWPLV 161
Cdd:COG1199 81 KDLPLLRKALGLPLRVALLKGRSNYLCLRRLEQ-ALQEGDDLDDEELLLARILAWASETWTGDRDELPL-PEDDELWRQV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 162 TSTNDNCLGSDCPLYKDCFVVKARKTAMDADVVVVNHHLFLADMVVKDsgfgELIPEADVMIFDEAHQLPDIASQYFGQS 241
Cdd:COG1199 159 TSDADNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALGE----ELLPEDDVLIIDEAHNLPDRARDMFSAE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 242 LSSRQLQDLAKDFTIAYRTelKDTQQLQKCADRLAQSAQDFRLQLGE-PGYRGNLRELLAD-KNIQRALLLLDDALELCY 319
Cdd:COG1199 235 LSSRSLLRLLRELRKLGLR--PGLKKLLDLLERLREALDDLFLALEEeEELRLALGELPDEpEELLEALDALRDALEALA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 320 DVAKLSLGRSALLDAAFERATLYRARLKR-LKEINQPGFSYWYECTSRHFTLALTPLTVADKFKEVMAQKPGSWIFTSAT 398
Cdd:COG1199 313 EALEEELERLAELDALLERLEELLFALARfLRIAEDEGYVRWLEREGGDVRLHAAPLDPADLLRELLFSRARSVVLTSAT 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 399 LSVNDDLHHFTGRLGIEQ-AESLLLPSPFDYETQALLCVPRNLPLPNQ-PGAARLLAAMLRPMIEANNGRCFMLCTSHAM 476
Cdd:COG1199 393 LSVGGPFDYFARRLGLDEdARTLSLPSPFDYENQALLYVPRDLPRPSDrDGYLEAIAEAIAELLEASGGNTLVLFTSYRA 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 477 MRDLAEQFRATMTLPVLLQGETSKGQLLQQFVSAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMED 556
Cdd:COG1199 473 LEQVAELLRERLDIPVLVQGDGSREALLERFREGGNSVLVGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREA 552
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 527036687 557 CRLRGGDPFDEVQLPDAVITLKQGVGRLIRDTDDRGVLVICDNRLVMRPYGATFLASLPPAPRTRdIKRAVRFLAN 632
Cdd:COG1199 553 LEARGGNGFMYAYLPPAVIKLKQGAGRLIRSEEDRGVVVLLDRRLLTKRYGKRFLDSLPPFRRTR-PEELRAFLER 627
|
|
| PRK08074 |
PRK08074 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
8-618 |
2.26e-128 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain] Cd Length: 928 Bit Score: 400.87 E-value: 2.26e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 8 EGQLAQAIPGFKPREPQRQMAHAVARAIDTAQPLVVEAGTGTGKTYAYLAP----ALRAKKKVIISTGSKALQDQLYSRD 83
Cdd:PRK08074 246 EEKLSLAMPKYEKREGQQEMMKEVYTALRDSEHALIEAGTGTGKSLAYLLPaayfAKKKEEPVVISTYTIQLQQQLLEKD 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 84 LPTVANALKYKGRLALLKGRSNYLCLERLEQqALAGGDlpvqTLSDVIILRA----WANQTEEGDISTcASVPEdSPA-- 157
Cdd:PRK08074 326 IPLLQKIFPFPVEAALLKGRSHYLCLRKFEQ-ALQEED----DNYDVALTKAqllvWLTETETGDLDE-LNLPS-GGKll 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 158 WPLVTSTNDNCLGSDCPLYKDCFVVKARKTAMDADVVVVNHHLFLADMVVKDSgfgeLIPEADVMIFDEAHQLPDIASQY 237
Cdd:PRK08074 399 WNRIASDGESDGGKQSPWFSRCFYQRAKNRAKFADLVITNHALLLTDLTSEEP----LLPSYEHIIIDEAHHFEEAASRH 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 238 FGQSLSSRQLQ-------------DLAKDFTIAYRTELKDTQQLQKC----------ADRLAQSAQDF------RLQLGE 288
Cdd:PRK08074 475 LGEQFSYMSFQlllsrlgtleedgLLSKLAKLFKKSDQASRSSFRDLdeslkelkfeADELFQMLRSFvlkrkkQEQNGR 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 289 PGYRGNlRELLADKNIQRALLLLDDALELCYDV-AKLSLGRSALLD-----AAFERATL--------YRARLKRLKEINQ 354
Cdd:PRK08074 555 LIYRYN-TESEKGKLWDAITELANRLCYDLRDLlTLLEAQKKELQEkmeseSAFLTGEYahlidlleKMAQLLQLLFEED 633
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 355 PGFSYWYECTSRHFTLALT----PLTVADKF-KEVMAQKPgSWIFTSATLSVNDDLHHFTGRLGIE--QAESLLLPSPFD 427
Cdd:PRK08074 634 PDYVTWIEIDAKGAINATRlyaqPVEVAERLaDEFFAKKK-SVILTSATLTVNGSFDYIIERLGLEdfYPRTLQIPSPFS 712
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 428 YETQALLCVPRNLPL---PNQPGAARLLAAMLRPMIEANNGRCFMLCTSHAMMRDLAEQFRATMTLP--VLL-QGET--S 499
Cdd:PRK08074 713 YEEQAKLMIPTDMPPikdVPIEEYIEEVAAYIAKIAKATKGRMLVLFTSYEMLKKTYYNLKNEEELEgyVLLaQGVSsgS 792
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 500 KGQLLQQFVSAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFDEVQLPDAVITLKQ 579
Cdd:PRK08074 793 RARLTKQFQQFDKAILLGTSSFWEGIDIPGDELSCLVIVRLPFAPPDQPVMEAKSEWAKEQGENPFQELSLPQAVLRFKQ 872
|
650 660 670
....*....|....*....|....*....|....*....
gi 527036687 580 GVGRLIRDTDDRGVLVICDNRLVMRPYGATFLASLPPAP 618
Cdd:PRK08074 873 GFGRLIRTETDRGTVFVLDRRLTTTSYGKYFLESLPTVP 911
|
|
| dinG |
PRK11747 |
ATP-dependent DNA helicase DinG; Provisional |
10-622 |
6.56e-113 |
|
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain] Cd Length: 697 Bit Score: 353.75 E-value: 6.56e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 10 QLAQAIPGFKPREPQRQMAHAVARAIDTAQP-----LVVEAGTGTGKTYAYLAP----ALRAKKKVIISTGSKALQDQLY 80
Cdd:PRK11747 16 ALQEQLPGFIPRAGQRQMIAEVAKTLAGEYLkdgriLVIEAGTGVGKTLSYLLAgipiARAEKKKLVISTATVALQEQLV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 81 SRDLPTVANALKYKGRLALLKGRSNYLCLERLE--------QQALAGGDLPVQTL---SDVIILRAWANQTEE----GDI 145
Cdd:PRK11747 96 SKDLPLLLKISGLDFKFTLAKGRGRYVCPRKLAalasdegtQQDLLLFLDDELTPpdeEEQKLLARLAKALATgkwdGDR 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 146 STCASVPEDSpAWPLVTSTNDNCLGSDCPLYKDCFVVKARKTAMDADVVVVNHHLFLADMvvkDSGFGELIPEADVMI-- 223
Cdd:PRK11747 176 DHWPEPIDDS-LWQRITTDKHSCLGRNCPYFRECPFFKARREIDEADVVVANHDLVLADL---ELGGGVVLPDPENLLyv 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 224 FDEAHQLPDIASQYFGQSLS----SRQLQDLAKDFT----IAYRTELKDTQQLQKCADRLAQSAQDFRLQL--------G 287
Cdd:PRK11747 252 LDEGHHLPDVARDHFAASAElkgtADWLEKLLKLLTklvaLIMEPPLALPERLNAHCEELRELLASLNQILnlflpaggE 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 288 EPGYR---GNLRELLadkniqrallllddaLELCYDVAKLSLG------------RSALLDAAFERATLYRA-------- 344
Cdd:PRK11747 332 EARYRfemGELPEEL---------------LELAERLAKLTEKllgllekllndlSEAMKTGKIDIVRLERLllelgral 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 345 -RLK----------RLKEINQPGFSYWYECTSR----HFTLALTPLTVADKFKEVMAQKPGSWIFTSATLSVNDDLHHFT 409
Cdd:PRK11747 397 gRLEalsklwrlaaKEDQESGAPMARWITREERdgqgDYLFHASPIRVGDQLERLLWSRAPGAVLTSATLRSLNSFDRFQ 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 410 GRLGI-EQAES--LLLPSPFDYETQALLCVPRNLPLPNQPGA-ARLLAAMLRPMIEANNGrCFMLCTSHAMMRDLAEQFR 485
Cdd:PRK11747 477 EQSGLpEKDGDrfLALPSPFDYPNQGKLVIPKMRAEPDNEEAhTAEMAEFLPELLEKHKG-SLVLFASRRQMQKVADLLP 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 486 ATMTLPVLLQGETSKGQLLQ---QFVSAGNA-LLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRG 561
Cdd:PRK11747 556 RDLRLMLLVQGDQPRQRLLEkhkKRVDEGEGsVLFGLQSFAEGLDLPGDYLTQVIITKIPFAVPDSPVEATLAEWLKSRG 635
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 527036687 562 GDPFDEVQLPDAVITLKQGVGRLIRDTDDRGVLVICDNRLVMRPYGATFLASLPPAPRTRD 622
Cdd:PRK11747 636 GNPFMEISVPDASFKLIQAVGRLIRSEQDRGRVTILDRRLLTKRYGKRLLDALPPFKREIE 696
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
17-615 |
1.00e-86 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 288.63 E-value: 1.00e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 17 GFKPREPQRQMAHAVARAIDTAQPLVVEAGTGTGKTYAYLAPAL---RAKKKVIISTGSKALQDQLYSRDLPTVANALKY 93
Cdd:TIGR01407 243 GLEYRPEQLKLAELVLDQLTHSEKSLIEAPTGTGKTLGYLLPALyyaITEKPVVISTNTKVLQSQLLEKDIPLLNEILNF 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 94 KGRLALLKGRSNYLCLERLEQqALAGGdlpvQTLSDVIILRA----WANQTEEGDISTCASVPEDSPAWPLVTStnDNCL 169
Cdd:TIGR01407 323 KINAALIKGKSNYLSLGKFSQ-ILKDN----TDNYEFNIFKMqvlvWLTETETGDLDELNLKGGNKMFFAQVRH--DGNL 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 170 GSDCPLYKDCFVVKARKTAMDADVVVVNHHLFLADMVVKDsgfgELIPEADVMIFDEAHQLPDIASQYFGQSLSSRQLQD 249
Cdd:TIGR01407 396 SKKDLFYEVDFYNRAQKNAEQAQILITNHAYLITRLVDNP----ELFPSFRDLIIDEAHHLPDIAENQLQEELDYADIKY 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 250 LAKDFTIAyrtelkDTQQLQKcadRLAQSAQDFRLQLG---EPGYRGNLRELLADKNIQRALlllddalelcyDVAKLSL 326
Cdd:TIGR01407 472 QIDLIGKG------ENEQLLK---RIQQLEKQEILEKLfdfETKDILKDLQAILDKLNKLLQ-----------IFSELSH 531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 327 grsALLDAAFERATLYRARLKRLKEINQPGFSYWYEC----TSRHFTLALTPLTVADKFKEVMAQKPGSWIFTSATLSVN 402
Cdd:TIGR01407 532 ---KTVDQLRKFDLALKDDFKNIEQSLKEGHTSWISIenlqQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSATLKFS 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 403 DDLHHFTGRLGIEQAE-SLLLPSPFDYETQALLCVPRNLPL---PNQPGAARLLAAMLRPMIEANNGRCFMLCTSHAMMR 478
Cdd:TIGR01407 609 HSFESFPQLLGLTDVHfNTIEPTPLNYAENQRVLIPTDAPAiqnKSLEEYAQEIASYIIEITAITSPKILVLFTSYEMLH 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 479 DLAEQFRATMT---LPVLLQGET-SKGQLLQQFVSAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARM 554
Cdd:TIGR01407 689 MVYDMLNELPEfegYEVLAQGINgSRAKIKKRFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANPKHPLTKKYW 768
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 527036687 555 EDCRLRGGDPFDEVQLPDAVITLKQGVGRLIRDTDDRGVLVICDNRLVMRPYGATFLASLP 615
Cdd:TIGR01407 769 QKLEQEGKNPFYDYVLPMAIIRLRQALGRLIRRENDRGSIVILDRRLVGKRYGKRFEKSLP 829
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
459-616 |
6.81e-50 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 170.82 E-value: 6.81e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 459 MIEANNGRCFMLCTSHAMMRDLAEQFRATMT---LPVLLQ-GETSKGQLLQQFVSAG-NALLVATS--SFWEGVDVRGDT 531
Cdd:pfam13307 3 LLKVIPGGVLVFFPSYSYLEKVAERLKESGLekgIEIFVQpGEGSREKLLEEFKKKGkGAVLFGVCggSFSEGIDFPGDL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 532 LSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFDEVQLPDAVITLKQGVGRLIRDTDDRGVLVICDNRLVMRPYGATFL 611
Cdd:pfam13307 83 LRAVIIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRYGKLLP 162
|
....*
gi 527036687 612 ASLPP 616
Cdd:pfam13307 163 KWLPP 167
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
474-603 |
1.42e-41 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 147.43 E-value: 1.42e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 474 HAMMRDLAEQFRATMTL----PVLLQGETSKG--QLLQQFVSAGN---ALLVATSS--FWEGVDVRGDTLSLVIIDKLPF 542
Cdd:smart00491 1 YRYLEQVVEYWKENGILeinkPVFIEGKDSGEteELLEKYSAACEargALLLAVARgkVSEGIDFPDDLGRAVIIVGIPF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 527036687 543 TSPDDPLLKARMEDCRLRG-GDPFDEVQLPDAVITLKQGVGRLIRDTDDRGVLVICDNRLVM 603
Cdd:smart00491 81 PNPDSPILRARLEYLDEKGgIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| PRK07246 |
PRK07246 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
10-614 |
3.74e-32 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 180905 [Multi-domain] Cd Length: 820 Bit Score: 132.89 E-value: 3.74e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 10 QLAQ------AIPGFKPREPQRQMAHAVARAIDTAQPLVVEAGTGTGKTYAYLAPALRAKK--KVIISTGSKALQDQLYS 81
Cdd:PRK07246 230 KLSQdfsiniALLGLEERPKQESFAKLVGEDFHDGPASFIEAQTGIGKTYGYLLPLLAQSDqrQIIVSVPTKILQDQIMA 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 82 RDLPTVANALKYKgrLALLKGRSNYLCLERLeQQALAGGD-------LPVQTLsdviilrAWANQTEEGDISTC------ 148
Cdd:PRK07246 310 EEVKAIQEVFHID--CHSLKGPQNYLKLDAF-YDSLQQNDdnrlvnrYKMQLL-------VWLTETETGDLDEIkqkqry 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 149 ASVPEDSpawplvtsTNDNCLGSDCPLYKDCFVVKARKTAMDADVVVVNHHLFLaDMVVKDSGFGElipeADVMIFDEAH 228
Cdd:PRK07246 380 AAYFDQL--------KHDGNLSQSSLFYDYDFWKRSYEKAKTARLLITNHAYFL-TRVQDDKDFAR----NKVLVFDEAQ 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 229 QLPDIASQYFGQSLS-SRQLQDLAKdftiAYRTELKDTQQlqkcadRLAQSAQDFRLQLGEPGYRGNLRELLADkniqra 307
Cdd:PRK07246 447 KLMLQLEQLSRHQLNiTSFLQTIQK----ALSGPLPLLQK------RLLESISFELLQLSEQFYQGKERQLIHD------ 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 308 llllddalelcyDVAKLSLGRSALLDAAFERatlyrarlkrLKEINQPGFS-YWYEcTSRHFTLALTPLTVADK----FK 382
Cdd:PRK07246 511 ------------SLSRLHQYFSELEVAGFQE----------LQAFFATAEGdYWLE-SEKQSEKRVTYLNSASKafthFS 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 383 EVM--AQKPgswIFTSATLSVNDDLHhFTGRLGIEQAESLLLPSpfDYETQALLCVPRNLPLPNQPG--------AARL- 451
Cdd:PRK07246 568 QLLpeTCKT---YFVSATLQISPRVS-LADLLGFEEYLFHKIEK--DKKQDQLVVVDQDMPLVTETSdevyaeeiAKRLe 641
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 452 -LAAMLRPMIEANNGRCFMLctshaMMRDLAEQfratMTLPVLLQGETSKG-QLLQQFVSAGNALLVATSSFWEGVD-VR 528
Cdd:PRK07246 642 eLKQLQQPILVLFNSKKHLL-----AVSDLLDQ----WQVSHLAQEKNGTAyNIKKRFDRGEQQILLGLGSFWEGVDfVQ 712
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 529 GDTLsLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFDEVQLPDAVITLKQGVGRLIRDTDDRGVLVICDNRLVMRPYGA 608
Cdd:PRK07246 713 ADRM-IEVITRLPFDNPEDPFVKKMNQYLLQEGKNPFYDYFLPMTILRLKQAIGRTMRREDQKSAVLILDRRILTKSYGK 791
|
....*.
gi 527036687 609 TFLASL 614
Cdd:PRK07246 792 QILASL 797
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
503-600 |
4.11e-10 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 58.77 E-value: 4.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 503 LLQQFVSAGNALL-VATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCR-------LRGGDPFDEvqlpDAV 574
Cdd:cd18788 57 YMERVVSRGALLLaVCRGKVSEGIDFSDDLGRAVIMVGIPYPNTKDPILKLKMDDLEylrdkglLTGEDWYTF----QAM 132
|
90 100
....*....|....*....|....*.
gi 527036687 575 ITLKQGVGRLIRDTDDRGVLVICDNR 600
Cdd:cd18788 133 RAVNQAIGRAIRHKNDYGAIVLLDKR 158
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
16-82 |
2.44e-06 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 48.64 E-value: 2.44e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 527036687 16 PGFKPREPQRQmahAVARAIDTAQPLVVEAGTGTGKTYAYLAPALRA-----KKKVIISTGSKALQDQLYSR 82
Cdd:smart00487 5 GFEPLRPYQKE---AIEALLSGLRDVILAAPTGSGKTLAALLPALEAlkrgkGGRVLVLVPTRELAEQWAEE 73
|
|
| DEXDc2 |
smart00488 |
DEAD-like helicases superfamily; |
18-247 |
8.98e-05 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214693 [Multi-domain] Cd Length: 289 Bit Score: 44.68 E-value: 8.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 18 FKPREPQRQMAHAVARAIDTAQPLVVEAGTGTGKTYAYLA---------PALRAKKKVIISTGS------------KALQ 76
Cdd:smart00488 7 YEPYPIQYEFMEELKRVLDRGKIGILESPTGTGKTLSLLCltltwlrsfPERIQKIKLIYLSRTvseiekrleelrKLMQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 77 DQLY-----SRDLPTVANAL---KYKGRLALLKGRSNyLCLERLEQQALAGGDLPVQTLSDVIILRAWANQTEEGDISTC 148
Cdd:smart00488 87 KVEYesdeeSEKQAQLLHELgreKPKVLGLSLTSRKN-LCLNPEVRTLKQNGLVVDEVCRSLTASKARKYRYENPKVERC 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 149 --------ASVPEDSPAWPLVTS--TNDNCLGSDCPLYKdcfvvkARKTAMDADVVVVNHHLFLADMV-------VKDSg 211
Cdd:smart00488 166 pfyentefLLVRDLLPAEVYDIEdlLELGKRLGGCPYFA------SRKAIEFANVVVLPYQYLLDPKIrqalsieLKDS- 238
|
250 260 270
....*....|....*....|....*....|....*.
gi 527036687 212 fgelipeadVMIFDEAHQLPDIASQYFGQSLSSRQL 247
Cdd:smart00488 239 ---------IVIFDEAHNLDNVCISALSSELSRRSL 265
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
18-82 |
9.71e-05 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 45.40 E-value: 9.71e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 527036687 18 FKPREPQRQMAHAVARAIDTA-QPLVVEAGTGTGKTY--AYLAPALRAKKKVIISTGSKALQDQLYSR 82
Cdd:COG1061 79 FELRPYQQEALEALLAALERGgGRGLVVAPTGTGKTVlaLALAAELLRGKRVLVLVPRRELLEQWAEE 146
|
|
| Csf4_U |
cd09708 |
CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly ... |
39-589 |
2.09e-04 |
|
CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DinG family DNA helicase
Pssm-ID: 187839 [Multi-domain] Cd Length: 632 Bit Score: 44.58 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 39 QPLVVEAGTGTGKTYAYLAPAL-----RAKKKVIISTGSKALQDQLYSRDLPTVANALKYKGRLALLKGRSNYLCLERLE 113
Cdd:cd09708 17 RIGMLEASTGVGKTLAMIMAALtmlkeRPDQKIAIAVPTLALMGQLWSELERLTAEGLAGPVQAGFFPGSQEFVSPGALQ 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 114 Q-----------QA------LAGGDLPVQ-----------TLSDVIILRAWANQTEEGDISTCASVPEDSPAWplVTSTN 165
Cdd:cd09708 97 ElldqsdgpgdkDAvvrlwmGQGGPRKVAplfnrmrdvtlLIHDTADIRGYVSYREQWDSLPRCSAMSRAPTK--MASMT 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 166 DNCLGSDCPLYKDcFVVKARKTAMDADVVVVNHHLFLADMVVKDSGFGE----LIPEADVMIFDEAHQLPDIASQYFGQS 241
Cdd:cd09708 175 HDLKALATLNPQD-FVTEDEEDKRWVTSLVESREYYARKSRILACTHTMlkwgLLPQPDILIVDEAHLFEQNISRVYSNA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 242 LSsrqLQDLAKDftiAYRTELKDTQQlqKCADRLAQSAQDFRLQLGEPGYRGNLRELLADKNIQRALLLLDDALELcydv 321
Cdd:cd09708 254 LS---LRMLRFH---LEVSHRKTGAI--GSAVVAAVSAVSHRLRQVSALGDGQTLCLDAGNKELETLFADLDAALE---- 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 322 AKLSLGRSALLDAAF-ERATLYRARLKRLKEINQPGFSYWYECTSRHFTLALTPLTVADKFKEVMAQKPGSWIFTSATLS 400
Cdd:cd09708 322 IKSTPNKKALSVVKDvKKARIILDNAITAIQGKQSTVYLQFSPDRRFPSLIVGREDLGKVMGGLWKDVTHGAIIVSATLY 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 401 VNDdlhhFTGRLGIEQAESLL-LP-----------SPFDYETQALLCVP---RNLPLPNQPGAARLLAAMLRPMIEA--- 462
Cdd:cd09708 402 LPD----RFGQMSCDYLKRVLsLPlsrldtpspivAPWVRNLIPHLHVPnakARFLLSRPVGKTEQGDANLAGWLENvsl 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 463 --------NNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSK-GQLLQQFVSAGNA----LLVATSSFWEGVDV-- 527
Cdd:cd09708 478 staailrkAQGGTLVLTTAFSHISAIGQLVELGIPAEIVIQSEKNRlASAEQQFLALYANgiqpVLIAAGGAWTGIDLhd 557
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 527036687 528 ------RGDTLSLVIIDKLPFTspddpLLKARMEDCRLRGGDPFDEVqLPDAVITLKQGVGRLIRDTD 589
Cdd:cd09708 558 psvspdKDNLLTDLIITCAPFG-----LNRSLSMLKRIRKTSVRPEI-INESLMMLRQGLGRLVRHPD 619
|
|
| DEXHc_RE |
cd17926 |
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family ... |
20-82 |
3.01e-04 |
|
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family is composed of helicase restriction enzymes and similar proteins such as TFIIH basal transcription factor complex helicase XPB subunit. These proteins are part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350684 [Multi-domain] Cd Length: 146 Bit Score: 41.52 E-value: 3.01e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 527036687 20 PREPQRQMAHAVaRAIDTAQPLVVEAGTGTGKTY-AYLAPALRAKKKVIISTGSKALQDQLYSR 82
Cdd:cd17926 1 LRPYQEEALEAW-LAHKNNRRGILVLPTGSGKTLtALALIAYLKELRTLIVVPTDALLDQWKER 63
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
32-82 |
6.53e-04 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 40.69 E-value: 6.53e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 32 ARAIDTAQP---LVVEAGTGTGKTYAYLAPALRA------KKKVIISTGSKALQDQLYSR 82
Cdd:pfam00270 5 AEAIPAILEgrdVLVQAPTGSGKTLAFLLPALEAldkldnGPQALVLAPTRELAEQIYEE 64
|
|
| rad3 |
TIGR00604 |
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are ... |
511-600 |
6.81e-04 |
|
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are DNA-DNA helicases that funciton in the initiation of transcription and nucleotide excision repair as part of the TFIIH complex. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273169 [Multi-domain] Cd Length: 705 Bit Score: 42.78 E-value: 6.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 527036687 511 GNALL-VATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEdcRLRGGDPFDEVQL---PDAVITLKQGVGRLIR 586
Cdd:TIGR00604 583 GAVLLsVAGGKVSEGIDFCDDLGRAVIMVGIPYEYTESRILLARLE--FLRDQYPIRENQDfyeFDAMRAVNQAIGRVIR 660
|
90
....*....|....
gi 527036687 587 DTDDRGVLVICDNR 600
Cdd:TIGR00604 661 HKDDYGSIVLLDKR 674
|
|
| DEXHc_Mtr4-like |
cd18024 |
DEXH-box helicase domain of ATP-dependent RNA helicase Mtr4; Mtr4 (also known as DOB1 or ... |
35-84 |
1.85e-03 |
|
DEXH-box helicase domain of ATP-dependent RNA helicase Mtr4; Mtr4 (also known as DOB1 or SKIV2L2) is a type II DEAD box helicase that plays a role in the processing of structured RNAs, including the maturation of 5.8S ribosomal RNA (rRNA)and is part of the TRAMP complex that is involved in exosome-mediated degradation of aberrant RNAs. Mtr4 belongs to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350782 [Multi-domain] Cd Length: 205 Bit Score: 40.12 E-value: 1.85e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 527036687 35 IDTAQPLVVEAGTGTGKT----YAyLAPALRAKKKVIISTGSKALQDQLYsRDL 84
Cdd:cd18024 44 IERNESVLVSAHTSAGKTvvaeYA-IAQSLRDKQRVIYTSPIKALSNQKY-REL 95
|
|
| Cas3 |
COG1203 |
CRISPR-Cas type I system-associated endonuclease/helicase Cas3 [Defense mechanisms]; ... |
18-82 |
9.88e-03 |
|
CRISPR-Cas type I system-associated endonuclease/helicase Cas3 [Defense mechanisms]; CRISPR-Cas type I system-associated endonuclease/helicase Cas3 is part of the Pathway/BioSystem: CRISPR-Cas system
Pssm-ID: 440816 [Multi-domain] Cd Length: 535 Bit Score: 38.91 E-value: 9.88e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 527036687 18 FKPREP----QRQMAHAVARAIDTAQPLVV-EAGTGTGKTYAYLAPALR-----AKKKVIISTGSKALQDQLYSR 82
Cdd:COG1203 122 SKPRTPinplQNEALELALEAAEEEPGLFIlTAPTGGGKTEAALLFALRlaakhGGRRIIYALPFTSIINQTYDR 196
|
|
| |
