glycosyltransferase family 9 protein may functions as a lipopolysaccharide heptosyltransferase involved in the biosynthesis of lipooligosaccharide (LOS)
lipopolysaccharide heptosyltransferase and similar proteins; Lipopolysaccharide ...
3-335
1.68e-51
lipopolysaccharide heptosyltransferase and similar proteins; Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340821 Cd Length: 277 Bit Score: 172.15 E-value: 1.68e-51
Glycosyltransferase family 9 (heptosyltransferase); Members of this family belong to ...
73-307
3.63e-11
Glycosyltransferase family 9 (heptosyltransferase); Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.
Pssm-ID: 395853 Cd Length: 247 Bit Score: 62.35 E-value: 3.63e-11
lipopolysaccharide heptosyltransferase II; This family consists of examples of ADP-heptose:LPS ...
3-288
1.30e-08
lipopolysaccharide heptosyltransferase II; This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
Pssm-ID: 274026 Cd Length: 334 Bit Score: 55.46 E-value: 1.30e-08
lipopolysaccharide heptosyltransferase and similar proteins; Lipopolysaccharide ...
3-335
1.68e-51
lipopolysaccharide heptosyltransferase and similar proteins; Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340821 Cd Length: 277 Bit Score: 172.15 E-value: 1.68e-51
Glycosyltransferase family 9 (heptosyltransferase); Members of this family belong to ...
73-307
3.63e-11
Glycosyltransferase family 9 (heptosyltransferase); Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.
Pssm-ID: 395853 Cd Length: 247 Bit Score: 62.35 E-value: 3.63e-11
lipopolysaccharide heptosyltransferase II; This family consists of examples of ADP-heptose:LPS ...
3-288
1.30e-08
lipopolysaccharide heptosyltransferase II; This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
Pssm-ID: 274026 Cd Length: 334 Bit Score: 55.46 E-value: 1.30e-08
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440471 [Multi-domain] Cd Length: 363 Bit Score: 41.27 E-value: 6.38e-04
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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