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Conserved domains on  [gi|544778753|ref|WP_021202635|]
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MULTISPECIES: protein translocase subunit SecF [Stenotrophomonas]

Protein Classification

protein translocase subunit SecF( domain architecture ID 11417410)

protein translocase subunit SecF is part of the Sec protein translocase complex; SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA

Gene Ontology:  GO:0015450|GO:0043952|GO:0065002
TCDB:  2.A.6.4

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 8-300 7.34e-109

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 318.53  E-value: 7.34e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753   8 ILPNDTKIDFMRWRHVAMAVTIVVFLASVAIIGIKGFNYALDFTGGTLIEARFDKAVDVEQVRTKLEQNGFEGAQVQSVG 87
Cdd:COG0341    2 LFPGNTNIDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTFG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  88 GNTDLLIRLAPHGEHAPGTGDAAAEDkataaavvkaLSTADNQATVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIA 167
Cdd:COG0341   82 SDNDVLIRTPPLDGESAEEVEKVRAA----------LKEAFGDVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIA 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 168 VRFEWKFAVtASIVAMF-DLIVTVAYVSLLGREFDLTVLAGLLSVMGFAINDIIVVFDRVRENFRSLRVDSM-EVLNRSI 245
Cdd:COG0341  152 FRFEWRFAV-GAVVALLhDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLaEIINLSI 230

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 544778753 246 NQTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHMIGAVIVVLSSILVAVPML 300
Cdd:COG0341  231 NQTLSRTINTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLL 285
 
Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 8-300 7.34e-109

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 318.53  E-value: 7.34e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753   8 ILPNDTKIDFMRWRHVAMAVTIVVFLASVAIIGIKGFNYALDFTGGTLIEARFDKAVDVEQVRTKLEQNGFEGAQVQSVG 87
Cdd:COG0341    2 LFPGNTNIDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTFG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  88 GNTDLLIRLAPHGEHAPGTGDAAAEDkataaavvkaLSTADNQATVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIA 167
Cdd:COG0341   82 SDNDVLIRTPPLDGESAEEVEKVRAA----------LKEAFGDVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIA 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 168 VRFEWKFAVtASIVAMF-DLIVTVAYVSLLGREFDLTVLAGLLSVMGFAINDIIVVFDRVRENFRSLRVDSM-EVLNRSI 245
Cdd:COG0341  152 FRFEWRFAV-GAVVALLhDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLaEIINLSI 230

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 544778753 246 NQTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHMIGAVIVVLSSILVAVPML 300
Cdd:COG0341  231 NQTLSRTINTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLL 285
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 7-300 1.88e-74

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 243.22  E-value: 1.88e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753   7 HILPNDTKIDFMRWRHVAMAVTIVVFLASVAIIGIKGFNYALDFTGGTLIEARFDKAVDVEQVRTKLEQNGFEGAQVQSV 86
Cdd:PRK13024 441 EGVTIFDRIDFVKKRKWFLIFSIVLVIAGIIIFFIFGLNLGIDFTGGTRYEIRTDQPVDLEQVRADLKELGLGEVNIVTF 520

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  87 GG-NTDLLIRLAPHGEhapgtgDAAAEDKATAAAVVKALSTADnQATVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIY 165
Cdd:PRK13024 521 GSdNNQVLVRTYGILS------DDEEADTEIVAKLKNALKNDK-GGTIPSSETVGPTVGKELARNAIIAVLIALIGILLY 593

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 166 IAVRFEWKFAVtASIVAM-FDLIVTVAYVSLLGREFDLTVLAGLLSVMGFAINDIIVVFDRVRENFRSLRVDSM-EVLNR 243
Cdd:PRK13024 594 ILIRFEWTFSL-GAILALlHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLYKKKDLrEIVNK 672

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 544778753 244 SINQTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHMIGAVIVVLSSILVAVPML 300
Cdd:PRK13024 673 SINQTLSRTINTSLTTLLVLLALLIFGGSSLRNFSLALLVGLIVGTYSSIFIAAPLW 729
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 43-296 1.25e-66

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 209.44  E-value: 1.25e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753   43 GFNYALDFTGGTLIEARFDKAVDVEQVRTKLEQNGFEGAQVQSVGGNTDLLIRLAPHgEHAPGTgdaaaedkATAAAVVK 122
Cdd:TIGR00966   1 GFNFGIDFTGGTVIETRLEQAADVAEVRDVLEKAGIEGVVIQEFGSSHTIMIRIPTL-DTEQSE--------ELREALEE 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  123 ALSTADNQATVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIAVRFEWKFAVtASIVAM-FDLIVTVAYVSLLGREFD 201
Cdd:TIGR00966  72 ALKNVDPDAEIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFAL-GAIVALvHDVIITVGVYSLFGIEVN 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  202 LTVLAGLLSVMGFAINDIIVVFDRVRENFRSL-RVDSMEVLNRSINQTLSRTVITAVMFFLSALALYLYGGSSMEGLAET 280
Cdd:TIGR00966 151 LTTVAALLTIIGYSINDTVVVFDRIRENLRKYtRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLA 230

                         250
                  ....*....|....*.
gi 544778753  281 HMIGAVIVVLSSILVA 296
Cdd:TIGR00966 231 LLVGVIVGTYSSIFIA 246
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 124-300 5.98e-47

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 157.00  E-value: 5.98e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  124 LSTADNQATVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIAVRFEWKFAVTASIVAMFDLIVTVAYVSLLGREFDLT 203
Cdd:pfam02355   6 LKNVGPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFGIEVDLA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  204 VLAGLLSVMGFAINDIIVVFDRVRENFRSLRVDSM-EVLNRSINQTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHM 282
Cdd:pfam02355  86 TVAALLTIIGYSVNDTVVVFDRVRENLRKKTRATLnEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALL 165

                         170
                  ....*....|....*...
gi 544778753  283 IGAVIVVLSSILVAVPML 300
Cdd:pfam02355 166 VGVIVGTYSSIFIASPIL 183
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 152-239 5.78e-06

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 47.85  E-value: 5.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  152 LYATIFMLAGFLIYIAVRFEWKFAVTASIVAMFDLIVTVAYVSLLGREFDLTVLAGLLSVMGFAINDIIVVFDRVRENFR 231
Cdd:NF037998  960 AISFAIILLALIVYILIRFKWTYYVALALAIVFAPAITVSIVIIFRVPITFEILIAFVSIIGFAIASAIIILGKAKSLIS 1039


                  ....*...
gi 544778753  232 SLRVDSME 239
Cdd:NF037998 1040 SKNKKELE 1047
 
Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 8-300 7.34e-109

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 318.53  E-value: 7.34e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753   8 ILPNDTKIDFMRWRHVAMAVTIVVFLASVAIIGIKGFNYALDFTGGTLIEARFDKAVDVEQVRTKLEQNGFEGAQVQSVG 87
Cdd:COG0341    2 LFPGNTNIDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTFG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  88 GNTDLLIRLAPHGEHAPGTGDAAAEDkataaavvkaLSTADNQATVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIA 167
Cdd:COG0341   82 SDNDVLIRTPPLDGESAEEVEKVRAA----------LKEAFGDVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIA 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 168 VRFEWKFAVtASIVAMF-DLIVTVAYVSLLGREFDLTVLAGLLSVMGFAINDIIVVFDRVRENFRSLRVDSM-EVLNRSI 245
Cdd:COG0341  152 FRFEWRFAV-GAVVALLhDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLaEIINLSI 230

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 544778753 246 NQTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHMIGAVIVVLSSILVAVPML 300
Cdd:COG0341  231 NQTLSRTINTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLL 285
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 7-300 1.88e-74

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 243.22  E-value: 1.88e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753   7 HILPNDTKIDFMRWRHVAMAVTIVVFLASVAIIGIKGFNYALDFTGGTLIEARFDKAVDVEQVRTKLEQNGFEGAQVQSV 86
Cdd:PRK13024 441 EGVTIFDRIDFVKKRKWFLIFSIVLVIAGIIIFFIFGLNLGIDFTGGTRYEIRTDQPVDLEQVRADLKELGLGEVNIVTF 520

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  87 GG-NTDLLIRLAPHGEhapgtgDAAAEDKATAAAVVKALSTADnQATVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIY 165
Cdd:PRK13024 521 GSdNNQVLVRTYGILS------DDEEADTEIVAKLKNALKNDK-GGTIPSSETVGPTVGKELARNAIIAVLIALIGILLY 593

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 166 IAVRFEWKFAVtASIVAM-FDLIVTVAYVSLLGREFDLTVLAGLLSVMGFAINDIIVVFDRVRENFRSLRVDSM-EVLNR 243
Cdd:PRK13024 594 ILIRFEWTFSL-GAILALlHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLYKKKDLrEIVNK 672

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 544778753 244 SINQTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHMIGAVIVVLSSILVAVPML 300
Cdd:PRK13024 673 SINQTLSRTINTSLTTLLVLLALLIFGGSSLRNFSLALLVGLIVGTYSSIFIAAPLW 729
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 43-296 1.25e-66

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 209.44  E-value: 1.25e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753   43 GFNYALDFTGGTLIEARFDKAVDVEQVRTKLEQNGFEGAQVQSVGGNTDLLIRLAPHgEHAPGTgdaaaedkATAAAVVK 122
Cdd:TIGR00966   1 GFNFGIDFTGGTVIETRLEQAADVAEVRDVLEKAGIEGVVIQEFGSSHTIMIRIPTL-DTEQSE--------ELREALEE 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  123 ALSTADNQATVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIAVRFEWKFAVtASIVAM-FDLIVTVAYVSLLGREFD 201
Cdd:TIGR00966  72 ALKNVDPDAEIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFAL-GAIVALvHDVIITVGVYSLFGIEVN 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  202 LTVLAGLLSVMGFAINDIIVVFDRVRENFRSL-RVDSMEVLNRSINQTLSRTVITAVMFFLSALALYLYGGSSMEGLAET 280
Cdd:TIGR00966 151 LTTVAALLTIIGYSINDTVVVFDRIRENLRKYtRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLA 230

                         250
                  ....*....|....*.
gi 544778753  281 HMIGAVIVVLSSILVA 296
Cdd:TIGR00966 231 LLVGVIVGTYSSIFIA 246
PRK14726 PRK14726
protein translocase subunit SecDF;
9-311 2.92e-59

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 203.80  E-value: 2.92e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753   9 LPNDTKIDFMRWRHVAMAVTIVVFLASVAIIGIKGFNYALDFTGGTLIEARFDKAV-DVEQVRTKLEQNGFEGAQVQSVG 87
Cdd:PRK14726 541 LFEGANIRFMGIRRYVFTLSAALSLASLVLFATVGLNLGIDFTGGSLIEVRAKQGNaDIADIRARLNELNLGEVQVERFG 620

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  88 GNTDLLIRLaphgeHAPGTGDAAAEDKATAAAvvkalSTADNQATVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIA 167
Cdd:PRK14726 621 SPRDALIRI-----ASQDGGENAEQSAVTLVR-----GELEDDYDFRRVEVVGPAVSGELTMAATLGVLAALAAILIYIW 690

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 168 VRFEWKFAVTASIVAMFDLIVTVAYVSLLGREFDLTVLAGLLSVMGFAINDIIVVFDRVRENFRSLRVDSMEVL-NRSIN 246
Cdd:PRK14726 691 IRFEWQFAVGAIIATLHDVILTLGLFVLTGIEFNLTSIAAILTIVGYSLNDTVVVYDRVRENLRRYKKMPLPILiDASIN 770

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 544778753 247 QTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHMIGAVIVVLSSILVAVPMLTIGFLRVSKQD 311
Cdd:PRK14726 771 QTLSRTVLTSATTLLALLALYLFGGEVIRSFTFAMLFGVAVGTFSSIYIAAPVLIVFKLRPESLD 835
secF PRK13021
preprotein translocase subunit SecF; Reviewed
 19-296 3.81e-48

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 237274 [Multi-domain]  Cd Length: 297  Bit Score: 163.49  E-value: 3.81e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  19 RWRHVAMAVTIVVFLASVAIIGIKGFNYALDFTGGTLIEARFDKAVDVEQVRTKLEQNGFEGAQVQSVGGNTDLLIRLA- 97
Cdd:PRK13021   8 KWRYISSAISIVLMLLSLTIIGVKGFNWGLDFTGGVVTEVQLDRKITSSELQPLLNAAYQQEVSVISASEPGRWVLRYAp 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  98 -PHGEHAPgtgdaaaedkataaAVVKALSTADNQATVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIAVRFEWKFAV 176
Cdd:PRK13021  88 aDTAQSNV--------------DIQQALAPLGTEVQVLNSSIVGPQVGQELAEQGGLALLVAMLCILGYLSYRFEWRLAS 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 177 TASIVAMFDLIVTVAYVSLLGREFDLTVLAGLLSVMGFAINDIIVVFDRVRENFRS-LRVDSMEVLNRSINQTLSRTVIT 255
Cdd:PRK13021 154 GALFALVHDVIFVLAFFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAkPKLAIQEINNQAIVATFSRTMVT 233

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 544778753 256 AVMFFLSALALYLYGGSSMEGLAETHMIGAVIVVLSSILVA 296
Cdd:PRK13021 234 SGTTLMTVGALWIMGGGPLEGFSIAMFIGILTGTFSSISVG 274
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 124-300 5.98e-47

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 157.00  E-value: 5.98e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  124 LSTADNQATVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIAVRFEWKFAVTASIVAMFDLIVTVAYVSLLGREFDLT 203
Cdd:pfam02355   6 LKNVGPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFGIEVDLA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  204 VLAGLLSVMGFAINDIIVVFDRVRENFRSLRVDSM-EVLNRSINQTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHM 282
Cdd:pfam02355  86 TVAALLTIIGYSVNDTVVVFDRVRENLRKKTRATLnEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALL 165

                         170
                  ....*....|....*...
gi 544778753  283 IGAVIVVLSSILVAVPML 300
Cdd:pfam02355 166 VGVIVGTYSSIFIASPIL 183
2A0604s01 TIGR00916
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ...
 138-293 2.76e-36

protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273336 [Multi-domain]  Cd Length: 192  Bit Score: 129.30  E-value: 2.76e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  138 FVGPQIGKDLAMNGLYATIFMLAGFLIYIAVRFEWKFAVTASIVAMFDLIVTVAYVSLLGREFDLTVLAGLLSVMGFAIN 217
Cdd:TIGR00916  36 TVGPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVILILGVLSLFGATLTLPGIAGLLTIIGYSVD 115

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544778753  218 DIIVVFDRVRENFRSL-RVDSMEVLNRSINQTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHMIGAVIVVLSSI 293
Cdd:TIGR00916 116 DTVVIFDRIREELRKYkGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
PRK13023 PRK13023
protein translocase subunit SecDF;
6-300 7.91e-35

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 134.36  E-value: 7.91e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753   6 LHILPNDTKIDFMRWRHVAMAVTIVVFLASVAIIGIKGFNYALDFTGGTLIE--ARFDKAvDVEQVRTKLEQNGFEGAQV 83
Cdd:PRK13023 444 LKLVPTVTHIPFMRLQFVTLGISVLACAIVVALFVNIGFNYGIDFRGGSMVElqARNGDA-NLEDINERLAELNIDSARV 522

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  84 QSVGGNTDLLIRLAPH--GEHAPGTgdaaaedkataaAVVKALSTADNQATVLRNEFVGPQIGKDLAMNGLYATIFMLAG 161
Cdd:PRK13023 523 LPAKSPRSALVIIGSQevGDDAEQT------------VAVKLRGEFEQDYSFQRVDVVGPTVSEQLSRAGVLAVILSLIG 590

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 162 FLIYIAVRFEWKFAVTASIVAMFDLIVTVAYVSLLGREFDLTVLAGLLSVMGFAINDIIVVFDRVRENFRSLRVDSM-EV 240
Cdd:PRK13023 591 IFIYVWFRFRWQLALGAVLSTLHDVVILSGMFIVFRMEFNLWSVAAILTIIGYSLNDTVVIYDRVRENLRRYKSAPLpAI 670

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 241 LNRSINQTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHMIGAVIVVLSSILVAVPML 300
Cdd:PRK13023 671 IDASINQTLSRTLLTSFVTFLAHVPLYAFGGSEIRMFALALSVGIIVASYSSIFIAAPLL 730
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 139-300 5.92e-20

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 90.69  E-value: 5.92e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  139 VGPQIGKDLAMNGLYATIFMLAGFLIYIAVRFEWKFAVTASIVAMFDLIVT----VAYVSLLGR-EFDLTVLAGLLSVMG 213
Cdd:PRK12911 1224 VSGQLSNKMRTQAVIALFGALGIILLYVSLRFEWRYAFSAICALIHDLLATcavlVALHFFLQKiQIDLQAIGALMTVLG 1303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  214 FAINDIIVVFDRVRENFRSLRVDSMEVL-NRSINQTLSRTVITAVMfFLSALALYLY-GGSSMEGLAETHMIGAVIVVLS 291
Cdd:PRK12911 1304 YSLNNTLIIFDRIREDRQEKLFTPMPILiNDALQKTLGRTVMTTAT-TLSVLLILLFvGGGSIFNFAFIMTIGILLGTLS 1382


                  ....*....
gi 544778753  292 SILVAVPML 300
Cdd:PRK12911 1383 SLYIAPPLL 1391
secD TIGR01129
protein-export membrane protein SecD; Members of this family are highly variable in length ...
 132-300 8.37e-13

protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273456 [Multi-domain]  Cd Length: 397  Bit Score: 68.47  E-value: 8.37e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  132 TVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIAVRFEWkFAVTASIVAMFDLIVTVAYVSLLGREFDLTVLAGLLSV 211
Cdd:TIGR01129 231 QILEERTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRL-FGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILT 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  212 MGFAINDIIVVFDRVRENFRslrvdsmevLNRSINQTL-------SRTVITA-VMFFLSALALYLYGGSSMEGLAETHMI 283
Cdd:TIGR01129 310 IGMAVDANVLIYERIKEELR---------LGKSVRQAIeagferaFSTIFDAnITTLIAALILYVFGTGPVKGFAVTLAI 380

                         170
                  ....*....|....*..
gi 544778753  284 GAVIVVLSSILVAVPML 300
Cdd:TIGR01129 381 GIIASLFTALVFTRLLL 397
PRK14726 PRK14726
protein translocase subunit SecDF;
132-316 1.01e-10

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 62.82  E-value: 1.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 132 TVLRNEFVGPQIGKDLAMNGLYATIF--MLAGFLIYIAVRFewkFAVTASIVAMFDLIVTVAYVSLLGREFDLTVLAGLL 209
Cdd:PRK14726 355 TVVEERTVGPGLGADSIAAGLVAGLIaaILVAALMIGFYGF---LGVIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIV 431

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 210 SVMGFAINDIIVVFDRVRENFRSLRvDSMEVLNRSINQTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHMIGAVIVV 289
Cdd:PRK14726 432 LTIGMAVDSNVLIYERIREEEKTGH-SLIQALDRGFSRALATIVDANVTILIAAVILFFLGSGAVRGFAVTLAVGILTTV 510

                        170       180
                 ....*....|....*....|....*..
gi 544778753 290 LSSILVAVPMLTiGFLRVSKQDLLPKA 316
Cdd:PRK14726 511 FTAFTLTRSLVA-VWLRRRRPKHLPKG 536
SecD COG0342
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ...
 132-298 4.81e-10

Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440111 [Multi-domain]  Cd Length: 434  Bit Score: 60.13  E-value: 4.81e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 132 TVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIAVRFeWKFAVTASIVAMFDLIVTVAYVSLLGREFDLTVLAGLLSV 211
Cdd:COG0342  254 EIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYY-RLPGLVANIALALNVVLLLGVLSLLGATLTLPGIAGIILT 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 212 MGFAINDIIVVFDRVRE---NFRSLRvdsmevlnRSINQTLSR---TVITA-VMFFLSALALYLYGGSSMEGLAETHMIG 284
Cdd:COG0342  333 IGMAVDANVLIFERIREelrAGRSLR--------AAIEAGFKRafsTILDAnVTTLIAAVVLFVLGTGPVKGFAVTLILG 404

                        170
                 ....*....|....
gi 544778753 285 avivVLSSILVAVP 298
Cdd:COG0342  405 ----ILISMFTAVP 414
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 133-305 2.35e-09

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 58.72  E-value: 2.35e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  133 VLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIAVRFewKFA-VTASIVAMFDLIVTVAYVSLLGREFDLTVLAGLLSV 211
Cdd:PRK12911  893 VLSEEVISPELGKSQRTQGIISVCLGLAVLIVLMSVYY--RFGgVIASGAVLLNLLLIWAALQYLDAPLTLSGLAGIVLA 970

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  212 MGFAINDIIVVFDRVRENFrslrvdsmeVLNRSINQTLSR-----------TVITAVMffLSALALYLYGGsSMEGLAET 280
Cdd:PRK12911  971 MGMAVDANVLVFERIREEY---------LLSRSLSESVEAgykkafsaifdSNLTTIL--ASALLLMLDTG-PIKGFALT 1038

                         170       180
                  ....*....|....*....|....*
gi 544778753  281 HMIGavivVLSSILVAVPMLTIGFL 305
Cdd:PRK12911 1039 LIIG----IFSSMFTALFMTKFFFM 1059
secD PRK05812
preprotein translocase subunit SecD; Reviewed
 126-309 3.94e-09

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 235615 [Multi-domain]  Cd Length: 462  Bit Score: 57.54  E-value: 3.94e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 126 TADNQATVLR------------NEFVGPQIGKDLAMNGLYATIFMLAGFLIYIAV--RFewkFAVTASIVAMFDLIVTVA 191
Cdd:PRK05812 262 EARDLALLLRagalpapleiveERTIGPSLGADSIRAGLIAGLIGLALVLLFMILyyRL---FGLIANIALVANLVLILA 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 192 YVSLLGREFDLTVLAGLLSVMGFAINDIIVVFDRVRE---NFRSLRvdsmevlnRSINQTLSR---TVITA-VMFFLSAL 264
Cdd:PRK05812 339 VLSLLGATLTLPGIAGIVLTIGMAVDANVLIFERIREelrEGRSLR--------SAIEAGFKRafsTILDSnITTLIAAI 410

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 544778753 265 ALYLYGGSSMEGLAETHMIGAVIVVLSSILVAVPMLTIGFLRVSK 309
Cdd:PRK05812 411 ILYALGTGPVKGFAVTLGIGILTSMFTAITVTRALVNLLYGRRKR 455
PRK13023 PRK13023
protein translocase subunit SecDF;
132-317 1.74e-08

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 55.78  E-value: 1.74e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 132 TVLRNEFVGPQIGKDLAMNGLYATifMLAGFLIYIAVRFEWK-FAVTASIVAMFDLIVTVAYVSLLGREFDLTVLAGLLS 210
Cdd:PRK13023 261 TVLEERTIASALGEDYASAAVLAA--LLAALVVGLFMVLSYGiLGVIALVALVVNIIILTAVLSLIGASISLASIAGLVL 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 211 VMGFAINDIIVVFDRVRENFRSlRVDSMEVLNRSINQTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHMIGaVIVVL 290
Cdd:PRK13023 339 TIGLAVDAHILIYERVREDRRK-GYSVVQAMESGFYRALSTIVDANLTTLIAALVLFLLGSGTVHGFALTVAIG-IGTTL 416

                        170       180
                 ....*....|....*....|....*..
gi 544778753 291 SSILVAVPMLTIGFLRVSKQDLLPKAK 317
Cdd:PRK13023 417 FTTLTFTRLLIAQWVRTAKPKEVPKRR 443
Sec_GG pfam07549
SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export ...
 38-64 1.72e-06

SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force. This alignment encompasses a -GG- motif typically found in N-terminal half of the SecD/SecF proteins.


Pssm-ID: 462205 [Multi-domain]  Cd Length: 27  Bit Score: 43.81  E-value: 1.72e-06
                          10        20
                  ....*....|....*....|....*..
gi 544778753   38 IIGIKGFNYALDFTGGTLIEARFDKAV 64
Cdd:pfam07549   1 SLFTRGLNLGLDFTGGTVIELQFDQPV 27
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 131-296 3.12e-06

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 48.69  E-value: 3.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 131 ATVLRNEFVGPQIGKDLAMNGLYATIFMLAGFLIYIAVrFEWKFAVTASIVAMFDLIVTVAYVSLLGREFDLTVLAGLLS 210
Cdd:PRK13024 248 LKIIESRSVGPTLGQDAIDAGIIAGIIGFALIFLFMLV-YYGLPGLIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVL 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753 211 VMGFAINDIIVVFDRVRENFR---SLRvDSMEVLNRSINQTLSRTVITAVmffLSALALYLYGGSSMEGLAETHMIGAVI 287
Cdd:PRK13024 327 GIGMAVDANVLIFERIKEELRkgkSLK-KAFKKGFKNAFSTILDSNITTL---IAAAILFFFGTGPVKGFATTLIIGILA 402


                 ....*....
gi 544778753 288 VVLSSILVA 296
Cdd:PRK13024 403 SLFTAVFLT 411
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 152-239 5.78e-06

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 47.85  E-value: 5.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  152 LYATIFMLAGFLIYIAVRFEWKFAVTASIVAMFDLIVTVAYVSLLGREFDLTVLAGLLSVMGFAINDIIVVFDRVRENFR 231
Cdd:NF037998  960 AISFAIILLALIVYILIRFKWTYYVALALAIVFAPAITVSIVIIFRVPITFEILIAFVSIIGFAIASAIIILGKAKSLIS 1039


                  ....*...
gi 544778753  232 SLRVDSME 239
Cdd:NF037998 1040 SKNKKELE 1047
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
 143-295 5.86e-03

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 38.28  E-value: 5.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544778753  143 IGKDLAMNGLYATIFMLAgFLIYIAVRFEWKFavTASIVAMFDLIVTVAYVSLLGREFDLTVLAGLLSVMGFAINDIIVV 222
Cdd:TIGR00921 191 FGKDMGTTMAISGILVVL-VLLLDFKRWWRPL--LPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQT 267

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544778753  223 FDRVRENFRSLRvDSMEVLNRSINQTLSRTVITAVMFFLSALALYLYGGSSMEGLAETHMIGAVIVVLSSILV 295
Cdd:TIGR00921 268 LNRYEEERDIGR-AKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLV 339
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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