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Conserved domains on  [gi|544824265|ref|WP_021240268|]
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MULTISPECIES: Ecr family regulatory small membrane protein [Enterobacter]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
sm_mem_Ecr NF033861
Ecr family regulatory small membrane protein; Ecr, as described in the genus Enterobacter, is ...
1-46 1.24e-12

Ecr family regulatory small membrane protein; Ecr, as described in the genus Enterobacter, is a small membrane protein predicted to span the inner membrane. It was found to modulate expression of PhoP, part of the PhoP-PhoQ two component system, which in turn induces the arnBCADTEF operon, leading to modification of LPS and conferring elevated resistance to colistin. The form described in PMID:31169899 (WP_048029797.1), at 72 amino acids in length, is aberrant compared with the typical length for the majority of family members, about 46 residues.


:

Pssm-ID: 411429  Cd Length: 46  Bit Score: 54.65  E-value: 1.24e-12
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 544824265  1 MGKTEIILTLIILLLIIFGFWFIFSGEIWYLVEFLENSLYPTFDAP 46
Cdd:NF033861  1 MSKTEIILLIIILLILIFGLWFIFSGEIWLLVSYLENSLYPTFDAP 46
 
Name Accession Description Interval E-value
sm_mem_Ecr NF033861
Ecr family regulatory small membrane protein; Ecr, as described in the genus Enterobacter, is ...
1-46 1.24e-12

Ecr family regulatory small membrane protein; Ecr, as described in the genus Enterobacter, is a small membrane protein predicted to span the inner membrane. It was found to modulate expression of PhoP, part of the PhoP-PhoQ two component system, which in turn induces the arnBCADTEF operon, leading to modification of LPS and conferring elevated resistance to colistin. The form described in PMID:31169899 (WP_048029797.1), at 72 amino acids in length, is aberrant compared with the typical length for the majority of family members, about 46 residues.


Pssm-ID: 411429  Cd Length: 46  Bit Score: 54.65  E-value: 1.24e-12
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 544824265  1 MGKTEIILTLIILLLIIFGFWFIFSGEIWYLVEFLENSLYPTFDAP 46
Cdd:NF033861  1 MSKTEIILLIIILLILIFGLWFIFSGEIWLLVSYLENSLYPTFDAP 46
 
Name Accession Description Interval E-value
sm_mem_Ecr NF033861
Ecr family regulatory small membrane protein; Ecr, as described in the genus Enterobacter, is ...
1-46 1.24e-12

Ecr family regulatory small membrane protein; Ecr, as described in the genus Enterobacter, is a small membrane protein predicted to span the inner membrane. It was found to modulate expression of PhoP, part of the PhoP-PhoQ two component system, which in turn induces the arnBCADTEF operon, leading to modification of LPS and conferring elevated resistance to colistin. The form described in PMID:31169899 (WP_048029797.1), at 72 amino acids in length, is aberrant compared with the typical length for the majority of family members, about 46 residues.


Pssm-ID: 411429  Cd Length: 46  Bit Score: 54.65  E-value: 1.24e-12
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 544824265  1 MGKTEIILTLIILLLIIFGFWFIFSGEIWYLVEFLENSLYPTFDAP 46
Cdd:NF033861  1 MSKTEIILLIIILLILIFGLWFIFSGEIWLLVSYLENSLYPTFDAP 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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