|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
231-468 |
6.36e-53 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 178.18 E-value: 6.36e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 231 ELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSSLSNREQ-EQVSIICNQGIKIRELVNDLNLVSKLE 309
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEEDLSPEERrELLEIIRESAERLLRLIEDLLDLSRLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 310 YNMQALNCDKIRVSAFLRELISEFINNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKS 389
Cdd:COG2205 81 SGKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544959485 390 DLDFCYIIVEDDGKGMSQERINSLLKSQNGLSEAyAKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPLIK 468
Cdd:COG2205 161 EGDGVRISVSDNGPGIPEEELERIFERFYRGDNS-RGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLPLAE 238
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
236-466 |
6.02e-43 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 154.30 E-value: 6.02e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 236 DEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESssLSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQAL 315
Cdd:COG0642 100 LLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEE--LDEEQREYLETILRSADRLLRLINDLLDLSRLEAGKLEL 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 316 NCDKIRVSAFLRELISEFINNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCY 395
Cdd:COG0642 178 EPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVRREGDRVR 257
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544959485 396 IIVEDDGKGMSQERINSLLK--SQnglSEAYAKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:COG0642 258 ISVEDTGPGIPPEDLERIFEpfFR---TDPSRRGGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTLPL 327
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
160-468 |
4.05e-39 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 145.85 E-value: 4.05e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 160 EIEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGILSDISKSINTVSKELQMKDEKL 239
Cdd:COG5002 79 LALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITEL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 240 RKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSSLSNREQEQ-VSIICNQGIKIRELVNDLNLVSKLEYNMQALNCD 318
Cdd:COG5002 159 ERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGAADDPEERREyLEIILEEAERLSRLVNDLLDLSRLESGELKLEKE 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 319 KIRVSAFLRELISEFINNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIV 398
Cdd:COG5002 239 PVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDDQVRISV 318
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544959485 399 EDDGKGMSQERINSLL-------KSQNGlseayaKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPLIK 468
Cdd:COG5002 319 RDTGIGIPEEDLPRIFerfyrvdKSRSR------ETGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITLPLAR 389
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
250-466 |
1.62e-26 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 111.21 E-value: 1.62e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 250 IAGISHDIRTPLSMIIGYAGELEESSSLSNREQEQ-----VSIICNQGIKIRELVNDLNLVSKleynMQALNCDKIRVSA 324
Cdd:COG5000 205 ARRIAHEIKNPLTPIQLSAERLRRKLADKLEEDREdleraLDTIIRQVDRLKRIVDEFLDFAR----LPEPQLEPVDLNE 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 325 FLRELISEFINNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKG 404
Cdd:COG5000 281 LLREVLALYEPALKEKDIRLELDLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDGRVRIEVSDNGPG 360
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 544959485 405 MSQERINSLLksqnglsEAY----AKGQnhGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:COG5000 361 IPEEVLERIF-------EPFfttkPKGT--GLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLPL 417
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
176-457 |
5.96e-20 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 92.54 E-value: 5.96e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 176 AIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGILSDISKSINTVSKELQMKDEKLRKKEEA--RSN----- 248
Cdd:COG4251 205 LLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEEELEERTAEleRSNeeleq 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 249 --WIAgiSHDIRTPLSMIIGYAGELEE--SSSLSNREQEQVSIICNQGIKIRELVNDLNLVSKLEynMQALNCDKIRVSA 324
Cdd:COG4251 285 faYVA--SHDLREPLRKISGFSQLLEEdyGDKLDEEGREYLERIRDAAERMQALIDDLLAYSRVG--RQELEFEPVDLNE 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 325 FLRELISEFINNNLDNDFYVEFDilnEDIIIDADKKLLKRAISNLIQNSITHNQQGCN--IRVTSKSDLDFCYIIVEDDG 402
Cdd:COG4251 361 LLEEVLEDLEPRIEERGAEIEVG---PLPTVRGDPTLLRQVFQNLISNAIKYSRPGEPprIEIGAEREGGEWVFSVRDNG 437
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 544959485 403 KGMS---QERINSLLKSQNGLSEayakGQNHGLGILIVSGIINAHRGKLDITSIDSQG 457
Cdd:COG4251 438 IGIDpeyAEKIFEIFQRLHSRDE----YEGTGIGLAIVKKIVERHGGRIWVESEPGEG 491
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
357-466 |
1.57e-19 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 83.85 E-value: 1.57e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 357 ADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILI 436
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRKIGGTGLGLSI 80
|
90 100 110
....*....|....*....|....*....|
gi 544959485 437 VSGIINAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITLPL 110
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
251-466 |
2.46e-19 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 89.09 E-value: 2.46e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 251 AGISHDIRTPLSMIIGYAGELEESSSLSNREQEQ---VSIICNQGIKIRELVNDL-NLVSKLEYNMQALNcdkirvsafL 326
Cdd:COG4191 147 AGIAHEINNPLAAILGNAELLRRRLEDEPDPEELreaLERILEGAERAAEIVRSLrAFSRRDEEEREPVD---------L 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 327 RELISE---FINNNL-DNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSI---THNQQGCnIRVTSKSDLDFCYIIVE 399
Cdd:COG4191 218 NELIDEaleLLRPRLkARGIEVELDLPPDLPPVLGDPGQLEQVLLNLLINAIdamEEGEGGR-ITISTRREGDYVVISVR 296
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544959485 400 DDGKGMSQERINSLLksqnglsEAY----AKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:COG4191 297 DNGPGIPPEVLERIF-------EPFfttkPVGKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITLPL 360
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
250-468 |
3.51e-19 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 88.75 E-value: 3.51e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 250 IAGISHDIRTPLSMIIGYAGELEESSSlSNREQEQVSIICNQGIKIRELVND-LNLVSKLEYNMQALNcdkirVSAFLRE 328
Cdd:COG3852 139 AAGLAHEIRNPLTGIRGAAQLLERELP-DDELREYTQLIIEEADRLNNLVDRlLSFSRPRPPEREPVN-----LHEVLER 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 329 LIsEFINNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDL----------DFCYIIV 398
Cdd:COG3852 213 VL-ELLRAEAPKNIRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIRTRVERqvtlgglrprLYVRIEV 291
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544959485 399 EDDGKGMSQERINSLLksqnglsEAY--AKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPLIK 468
Cdd:COG3852 292 IDNGPGIPEEILDRIF-------EPFftTKEKGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYLPLEQ 356
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
238-465 |
1.54e-18 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 87.37 E-value: 1.54e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 238 KLRKKEEARSNWIAGISHDIRTPLSMIIGYAgELEESSSLSNREQEQV-SIICNQGIKIRELVNDLNLVSKLEYN-MQAL 315
Cdd:PRK11006 196 QMHQLEGARRNFFANVSHELRTPLTVLQGYL-EMMQDQPLEGALREKAlHTMREQTQRMEGLVKQLLTLSKIEAApTIDL 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 316 NcDKIRVSAFLRELISEFINNNlDNDFYVEFDIlNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCY 395
Cdd:PRK11006 275 N-EKVDVPMMLRVLEREAQTLS-QGKHTITFEV-DNSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQGAE 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 396 IIVEDDGKGMSQERINSLLK----------SQNGLSeayakgqnhGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLP 465
Cdd:PRK11006 352 FSVEDNGPGIAPEHIPRLTErfyrvdkarsRQTGGS---------GLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLP 422
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
362-464 |
8.10e-18 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 78.41 E-value: 8.10e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 362 LKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSQNGLSEAYaKGQNHGLGILIVSGII 441
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSR-EGGGTGLGLAIVRRIV 79
|
90 100
....*....|....*....|...
gi 544959485 442 NAHRGKLDITSIDSQGLKTILKL 464
Cdd:cd00075 80 EAHGGRITVESEPGGGTTFTVTL 102
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
243-466 |
6.99e-17 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 82.65 E-value: 6.99e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 243 EEARSNWIAGISHDIRTPLSMIiGYAGEL--EESSSLSNreqeqvSII-----CNqGIkIRELVNDLNLVSKLEYNMQAL 315
Cdd:PRK09467 226 EDDRTLLMAGVSHDLRTPLTRI-RLATEMmsEEDGYLAE------SINkdieeCN-AI-IEQFIDYLRTGQEMPMEMADL 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 316 NcdkirvsaflrELISEFINNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQqGCnIRVTSKSDLDFCY 395
Cdd:PRK09467 297 N-----------ALLGEVIAAESGYEREIETALQPGPIEVPMNPIAIKRALANLVVNAARYGN-GW-IKVSSGTEGKRAW 363
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544959485 396 IIVEDDGKGMSQERINSLLksqnglsEAYAKGQN------HGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:PRK09467 364 FQVEDDGPGIPPEQLKHLF-------QPFTRGDSargssgTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLPL 433
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
357-466 |
3.67e-16 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 73.94 E-value: 3.67e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 357 ADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDlDFCYIIVEDDGKGMSQERINSLLksQNGLSEAYAKGQNHGLGILI 436
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSEG-GELTLTVEDNGIGIPPEDLPRIF--EPFSTADKRGGGGTGLGLSI 77
|
90 100 110
....*....|....*....|....*....|
gi 544959485 437 VSGIINAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:pfam02518 78 VRKLVELLGGTITVESEPGGGTTVTLTLPL 107
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
250-466 |
1.93e-15 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 78.11 E-value: 1.93e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 250 IAGISHDIRTPLSMIiGYagELEESSSLSnrEQEQVSIicNQGI-KIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRE 328
Cdd:PRK10604 216 IDGIAHELRTPLVRL-RY--RLEMSDNLS--AAESQAL--NRDIgQLEALIEELLTYARLDRPQNELHLSEPDLPAWLST 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 329 LISEFinNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQgcNIRVTSKSDLDFCYIIVEDDGKGMSQE 408
Cdd:PRK10604 289 HLADI--QAVTPEKTVRLDTPHQGDYGALDMRLMERVLDNLLNNALRYAHS--RVRVSLLLDGNQACLIVEDDGPGIPPE 364
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 409 RINSLLKSQNGL--SEAYAKGqNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:PRK10604 365 ERERVFEPFVRLdpSRDRATG-GCGLGLAIVHSIALAMGGSVNCDESELGGARFSFSWPV 423
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
216-466 |
7.33e-15 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 76.69 E-value: 7.33e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 216 GILSDISKsiNTVSKELQMKDEKLRKKEEARsnwiAGISHDIRTPLSMIIGYAGELEESSslsNREQEQVSIICNQGIKI 295
Cdd:COG5805 263 VILRDITE--KKEAEELMARSEKLSIAGQLA----AGIAHEIRNPLTSIKGFLQLLQPGI---EDKEEYFDIMLSELDRI 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 296 RELVNDLNLVSK-LEYNMQALNCDKIrvsafLRELIS----EFINNNLDndfyVEFDILNEDIIIDADKKLLKRAISNLI 370
Cdd:COG5805 334 ESIISEFLALAKpQAVNKEKENINEL-----IQDVVTlletEAILHNIQ----IRLELLDEDPFIYCDENQIKQVFINLI 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 371 QNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLlksqnGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI 450
Cdd:COG5805 405 KNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEERLKKL-----GEPFFTTKEKGTGLGLMVSYKIIENHNGTIDI 479
|
250
....*....|....*.
gi 544959485 451 TSIDSQGLKTILKLPL 466
Cdd:COG5805 480 DSKVGKGTTFTITLPL 495
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
233-467 |
1.10e-14 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 75.98 E-value: 1.10e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 233 QMKDEKLRK-KEEARSNWIAGISHDIRTPLSMIIGYAGELEESSSLSNREQEQVSIICNQGIKIRELVNDL-NLVSKLEY 310
Cdd:PRK10364 223 LLQDEMKRKeKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELlELVKPTHL 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 311 NMQAlncdkIRVSAFLR---ELISEFINNNldnDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTS 387
Cdd:PRK10364 303 ALQA-----VDLNDLINhslQLVSQDANSR---EIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTA 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 388 KSDLDFCYIIVEDDGKGMSQERINSLLksqnglsEAY--AKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLP 465
Cdd:PRK10364 375 SESGAGVKISVTDSGKGIAADQLEAIF-------TPYftTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLP 447
|
..
gi 544959485 466 LI 467
Cdd:PRK10364 448 VN 449
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
246-465 |
8.30e-14 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 73.27 E-value: 8.30e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 246 RSNWIAGISHDIRTPLSMIIGYAgELEESSSLSNREQEQVsIICN--QGIKIRELVNDLNLVSKLEYNMQALNCDKIRVS 323
Cdd:PRK09835 262 QSNFSADIAHEIRTPITNLITQT-EIALSQSRSQKELEDV-LYSNleELTRMAKMVSDMLFLAQADNNQLIPEKKMLDLA 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 324 AflrELISEFinnnldnDFY--------VEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCY 395
Cdd:PRK09835 340 D---EVGKVF-------DFFeawaeergVELRFVGDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQ 409
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544959485 396 IIVEDDGKGMSQERINSLLKSQNGLSEAYA-KGQNHGLGILIVSGIINAHRGKLDITSiDSQGLKTILKLP 465
Cdd:PRK09835 410 LVVENPGTPIAPEHLPRLFDRFYRVDPSRQrKGEGSGIGLAIVKSIVVAHKGTVAVTS-DARGTRFVISLP 479
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
5-468 |
1.11e-13 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 72.74 E-value: 1.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 5 KYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSDNLDTSDSREIKSNLIMIEDNLILRNGKFILDDSSKEVLHK 84
Cdd:COG2972 3 KSLSLLSIVLLLLILLLLVLLILLLSLLLIILLLLLLLILLLLLLILLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 85 NKVWAMLIDNNGDRIWGFDLPKEIPSHYT-LTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKfnltytvkEIEQ 163
Cdd:COG2972 83 LLLLLLLLLLLILLLSLLLLLALILLLALlLLLSILLLILGLLLIILLLLSLLGWTLVSLIPKSELFR--------GLFS 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 164 FPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGI--LSDISKSINTVSKELQ--MKDEKL 239
Cdd:COG2972 155 LRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLVRLEVSGNdeIGILARSFNEMVERIKelIEEVYE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 240 RKKEEARSNWIAGIS----HDIRTPLSMIIGYAgeleesssLSNREQEqvsiicnqgikIRELVNDLnlVSKLEYNMQAL 315
Cdd:COG2972 235 LELEKKEAELKALQAqinpHFLFNTLNSIRWLA--------ELEDPEE-----------AEEMLEAL--SKLLRYSLSKG 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 316 NcDKIRVS---AFLRELIS-EFINnnLDNDFYVEFDIlnEDIIIDAdkKLLKRAISNLIQNSITH----NQQGCNIRVTS 387
Cdd:COG2972 294 D-ELVTLEeelELIKSYLEiQKLR--FGDRLEVEIEI--DEELLDL--LIPKLILQPLVENAIEHgiepKEGGGTIRISI 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 388 KSDLDFCYIIVEDDGKGMSQERINSLlksqngLSEAYAKGQNHGLGILIVSGIINAHRGK---LDITSIDSQGLKTILKL 464
Cdd:COG2972 367 RKEGDRLVITVEDNGVGMPEEKLEKL------LEELSSKGEGRGIGLRNVRERLKLYYGEeygLEIESEPGEGTTVTIRI 440
|
....
gi 544959485 465 PLIK 468
Cdd:COG2972 441 PLEE 444
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
166-465 |
1.76e-13 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 72.17 E-value: 1.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 166 MLIIGMFLVNAIVTFLIALfiGLKmvKSIKPIITGIKLMSKGE---PVLLQEKGILSDISKSINTVSkelqmkdEKLRKK 242
Cdd:NF012163 168 LIVALALLLAALAAFLLAR--GLL--APVKRLVEATHRLAAGDyttRVTPTSNDELGKLAQDFNQLA-------STLEKN 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 243 EEARSNWIAGISHDIRTPLSMIigyAGELEE-SSSLSNREQEQVSIICNQGIKIRELVNDLNLVSKLEynMQALNCDKIR 321
Cdd:NF012163 237 EQMRRDFMADISHELRTPLAVL---RAELEAiQDGIRKFTPESLDSLQAEVGTLTKLVDDLHDLSMSD--EGALAYQKAS 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 322 VS--AFLRELISEFINNNLDNDFYVEFDiLNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVE 399
Cdd:NF012163 312 VDlvPLLEVEGGAFRERFASAGLELEVS-LPDSSLVFGDRDRLMQLFNNLLENSLRYTDSGGSLHISASQRPKEVTLTVA 390
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544959485 400 DDGKGMSQERINSLLKS--QNGLSEAYAKGQNhGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLP 465
Cdd:NF012163 391 DSAPGVSDEQLARLFERfyRVEVSRNRASGGS-GLGLAISLNIVQAHGGTLHAAHSPLGGLRIVVTLP 457
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
217-466 |
2.63e-13 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 71.92 E-value: 2.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 217 ILSDIsksinTVSKELQmkdEKLRKKEE--ARSNWIAGISHDIRTPLSMIIGYAGELEESSSLsNREQEQVSIICNQGIK 294
Cdd:PRK11360 367 IFSDL-----TERKRLQ---RRVARQERlaALGELVAGVAHEIRNPLTAIRGYVQIWRQQTSD-PPSQEYLSVVLREVDR 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 295 IRELVNDLNLVSK-LEYNMQalncdKIRVSAFLRELISEFINNNLDNDFYVEFDiLNEDI-IIDADKKLLKRAISNLIQN 372
Cdd:PRK11360 438 LNKVIDQLLEFSRpRESQWQ-----PVSLNALVEEVLQLFQTAGVQARVDFETE-LDNELpPIWADPELLKQVLLNILIN 511
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 373 SITHNQQGCNIRV-TSKSDLDFCYIIVEDDGKGMSQErinSLLKSQNGLSEAYAKGQnhGLGILIVSGIINAHRGKLDIT 451
Cdd:PRK11360 512 AVQAISARGKIRIrTWQYSDGQVAVSIEDNGCGIDPE---LLKKIFDPFFTTKAKGT--GLGLALSQRIINAHGGDIEVE 586
|
250
....*....|....*
gi 544959485 452 SIDSQGLKTILKLPL 466
Cdd:PRK11360 587 SEPGVGTTFTLYLPI 601
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
231-466 |
4.79e-13 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 70.77 E-value: 4.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 231 ELQMKDEKLRKKEeaRSNWI----AGISHDIRTPLSMIIGYAGELEEssSLSNREQEQVSIICNQGIKIRELVNDLNLVS 306
Cdd:COG5809 253 ERKKLEELLRKSE--KLSVVgelaAGIAHEIRNPLTSLKGFIQLLKD--TIDEEQKTYLDIMLSELDRIESIISEFLVLA 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 307 KleynMQALNCDKIRVSAFLRELISEFINNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRV- 385
Cdd:COG5809 329 K----PQAIKYEPKDLNTLIEEVIPLLQPQALLKNVQIELELEDDIPDILGDENQLKQVFINLLKNAIEAMPEGGNITIe 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 386 TSKSDLDFCYIIVEDDGKGMSQERINSllksqngLSEAYA--KGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILK 463
Cdd:COG5809 405 TKAEDDDKVVISVTDEGCGIPEERLKK-------LGEPFYttKEKGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSIT 477
|
...
gi 544959485 464 LPL 466
Cdd:COG5809 478 LPI 480
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
243-307 |
1.01e-12 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 63.00 E-value: 1.01e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 544959485 243 EEARSNWIAGISHDIRTPLSMIIGYAGELEESSSLSNREQEQVSIICNQGIKIRELVNDLNLVSK 307
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
362-466 |
3.06e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 62.73 E-value: 3.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 362 LKRAISNLIQNSITHNQQgcNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSQNGLSEAY-AKGQNHGLGILIVSGI 440
Cdd:cd16949 1 LARALENVLRNALRYSPS--KILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARdRESGGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*.
gi 544959485 441 INAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRIWLPA 104
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
180-466 |
3.12e-12 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 68.33 E-value: 3.12e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 180 FLIALFIGLKM----VKSIKPIITGIKLMSKGEPVLLQEKGilsdiSKSINTVSKELqmkdEKLRKKEEARsNWIAG--- 252
Cdd:PRK11100 192 LGIALLIGAGVvwwlNRSIRRLTRYADAVTEGKPVPLPKLG-----SSELRELAQAL----ESMRVKLEGK-AYVEQyvq 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 253 -ISHDIRTPLSMIIGyAGELEESSSLSNREQEQVSIICNQGIKIRELVNDLNLVSKLEyNMQAL-NCDKIRVSAFLRELI 330
Cdd:PRK11100 262 tLTHELKSPLAAIRG-AAELLQEDPPPEDRARFTGNILTQSARLQQLIDRLLELARLE-QRQELeVLEPVALAALLEELV 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 331 SEFI----NNNldndfyVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKG-- 404
Cdd:PRK11100 340 EAREaqaaAKG------ITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGPGip 413
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544959485 405 ---MSQ--ERINSLLKSQNGLseayaKGQnhGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:PRK11100 414 dyaLPRifERFYSLPRPANGR-----KST--GLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPR 473
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
245-309 |
1.05e-11 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 59.89 E-value: 1.05e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 544959485 245 ARSNWIAGISHDIRTPLSMIIGYAgELEESSSLSNREQEQVSIICNQGIKIRELVNDLNLVSKLE 309
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYL-ELLLDTELSEEQREYLETILREAERLLRLINDLLDLSRIE 64
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
245-309 |
2.15e-11 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 59.15 E-value: 2.15e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 544959485 245 ARSNWIAGISHDIRTPLSMIIGYAgELEESSSLSNREQEQVSIICNQGIKIRELVNDLNLVSKLE 309
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYL-ELLRDEKLDEEQREYLETILRSAERLLRLINDLLDLSRIE 64
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
239-466 |
2.68e-11 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 65.42 E-value: 2.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 239 LRKKEEARSNWIAGISHDIRTPLSMIigyAGELE-----------ES-SSLsnreQEQVSIICnqgikirELVNDLNLVS 306
Cdd:PRK10549 233 LEKNEQMRRDFMADISHELRTPLAVL---RGELEaiqdgvrkftpESvASL----QAEVGTLT-------KLVDDLHQLS 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 307 -----KLEYNMQALNCD---KIRVSAFLRELISEFINNNLDndfyvefdiLNEDIIIDADKKLLKRAISNLIQNSITHNQ 378
Cdd:PRK10549 299 lsdegALAYRKTPVDLVpllEVAGGAFRERFASRGLTLQLS---------LPDSATVFGDPDRLMQLFNNLLENSLRYTD 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 379 QGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLK-------SQNglseaYAKGQNhGLGILIVSGIINAHRGKLDIT 451
Cdd:PRK10549 370 SGGSLHISAEQRDKTLRLTFADSAPGVSDEQLQKLFErfyrtegSRN-----RASGGS-GLGLAICLNIVEAHNGRIIAA 443
|
250
....*....|....*
gi 544959485 452 SIDSQGLKTILKLPL 466
Cdd:PRK10549 444 HSPFGGVSITVELPL 458
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
241-466 |
3.49e-11 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 65.70 E-value: 3.49e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 241 KKEEARSNWIAGISHDIRTPLSMIIGYAgELEESSSLSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQ------- 313
Cdd:PRK11466 439 KASQAKSAFLAAMSHEIRTPLYGILGTA-QLLADNPALNAQRDDLRAITDSGESLLTILNDILDYSAIEAGGKnvsvsde 517
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 314 ----------ALNCDKIRVSAFLRELISEFInnnldndfyvefDILNEdiIIDADKKLLKRAISNLIQNSITHNQQGcNI 383
Cdd:PRK11466 518 pfeprpllesTLQLMSGRVKGRPIRLATDIA------------DDLPT--ALMGDPRRIRQVITNLLSNALRFTDEG-SI 582
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 384 RVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSqngLSEAYAKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILK 463
Cdd:PRK11466 583 VLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQP---FVQVSGKRGGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLR 659
|
...
gi 544959485 464 LPL 466
Cdd:PRK11466 660 LPL 662
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
220-466 |
4.00e-11 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 65.53 E-value: 4.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 220 DISKSINTVSKeLQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAgELEESSSLSNREQ-EQVSIICNQGIKIREL 298
Cdd:PRK09959 687 DITETRDLIHA-LEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFL-ELLSGSGLSKEQRvEAISLAYATGQSLLGL 764
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 299 VNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFINNNLDNDFYVEFDILNED-IIIDADKKLLKRAISNLIQNSITHN 377
Cdd:PRK09959 765 IGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHSFGAIAASKSIALSCSSTFPDhYLVKIDPQAFKQVLSNLLSNALKFT 844
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 378 QQGCNIRVTSKSDLDFCYIIVE----DDGKGMSQERINSLLKSQNGLSeAYAKGQNHGLGILIVSGIINAHRGKLDITSI 453
Cdd:PRK09959 845 TEGAVKITTSLGHIDDNHAVIKmtimDSGSGLSQEEQQQLFKRYSQTS-AGRQQTGSGLGLMICKELIKNMQGDLSLESH 923
|
250
....*....|...
gi 544959485 454 DSQGLKTILKLPL 466
Cdd:PRK09959 924 PGIGTTFTITIPV 936
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
242-466 |
1.23e-10 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 63.90 E-value: 1.23e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 242 KEEARSNWIAGISHDIRTPLSMIIGYAGELEES-SSLSNREQEQVSIICNQGIKIRELVNDL-----------NLvsKLE 309
Cdd:PRK10490 660 REQLRNALLAALSHDLRTPLTVLFGQAEILTLDlASEGSPHARQASEIRQQVLNTTRLVNNLldmariqsggfNL--RKE 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 310 YnmQALncDKIRVSAfLRELisefinNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSI--THNQQGCNIRVTS 387
Cdd:PRK10490 738 W--LTL--EEVVGSA-LQML------EPGLSGHPINLSLPEPLTLIHVDGPLFERVLINLLENAVkyAGAQAEIGIDAHV 806
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 388 KSdlDFCYIIVEDDGKGMSQERINSLL-KSQNGLSEAYAKGQnhGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:PRK10490 807 EG--ERLQLDVWDNGPGIPPGQEQLIFdKFARGNKESAIPGV--GLGLAICRAIVEVHGGTIWAENRPEGGACFRVTLPL 882
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
362-465 |
7.67e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 55.92 E-value: 7.67e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 362 LKRAISNLIQNSITHNqqGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSqnglseaYAKGQNH------GLGIL 435
Cdd:cd16950 1 LKRVLSNLVDNALRYG--GGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQP-------FYRGDNArgtsgtGLGLA 71
|
90 100 110
....*....|....*....|....*....|
gi 544959485 436 IVSGIINAHRGKLDITSIDSQGLKTILKLP 465
Cdd:cd16950 72 IVQRISDAHGGSLTLANRAGGGLCARIELP 101
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
342-452 |
1.79e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 55.60 E-value: 1.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 342 FYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSQNGLS 421
Cdd:cd16947 1 FQVEINIPDRPIYANANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLE 80
|
90 100 110
....*....|....*....|....*....|..
gi 544959485 422 EAYAKG-QNHGLGILIVSGIINAHRGKLDITS 452
Cdd:cd16947 81 DSRNSAkQGNGLGLTITKRLAESMGGSIYVNS 112
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
253-468 |
4.92e-09 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 58.41 E-value: 4.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 253 ISHDIRTPLSmiigyagELEESSSLSNR---EQEQVSIICNQGIKIRELVNDLNLVSKLEYNmQALNCDKIRVSAFLREL 329
Cdd:PRK09470 250 ISHELRTPLT-------RLQLATALLRRrqgESKELERIETEAQRLDSMINDLLVLSRNQQK-NHLERETFKANSLWSEV 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 330 I--SEFINNNLDNDFYVEFDIlnEDIIIDADKKLLKRAISNLIQNSI--THNQqgcnIRVTSKSDLDFCYIIVEDDGKGM 405
Cdd:PRK09470 322 LedAKFEAEQMGKSLTVSAPP--GPWPINGNPNALASALENIVRNALrySHTK----IEVAFSVDKDGLTITVDDDGPGV 395
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544959485 406 SQERINSLLKSQNGLSEAYAK---GQnhGLGILIVSGIINAHRGKldITSIDSQ--GLKTILKLPLIK 468
Cdd:PRK09470 396 PEEEREQIFRPFYRVDEARDResgGT--GLGLAIVENAIQQHRGW--VKAEDSPlgGLRLTIWLPLYK 459
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
294-466 |
6.58e-09 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 57.55 E-value: 6.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 294 KIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFINNNLDndFYVEFDILNEDIIIDADKklLKRAISNLIQNS 373
Cdd:COG3290 218 EALEYIDEISEELQELIDSLLSRIGNPVLAALLLGKAARARERGID--LTIDIDSDLPDLPLSDTD--LVTILGNLLDNA 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 374 ITHNQQGCN----IRVTSKSDLDFCYIIVEDDGKGMSQERINSLLksQNGLSEAyaKGQNHGLGILIVSGIINAHRGKLD 449
Cdd:COG3290 294 IEAVEKLPEeerrVELSIRDDGDELVIEVEDSGPGIPEELLEKIF--ERGFSTK--LGEGRGLGLALVKQIVEKYGGTIE 369
|
170
....*....|....*..
gi 544959485 450 ITSIDSQGLKTILKLPL 466
Cdd:COG3290 370 VESEEGEGTVFTVRLPK 386
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
358-463 |
9.65e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 52.85 E-value: 9.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 358 DKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIV 437
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSGGHYGMGLYIA 80
|
90 100
....*....|....*....|....*.
gi 544959485 438 SGIINAHRGKLDITSIDSQGLKTILK 463
Cdd:cd16975 81 KNLVEKHGGSLIIENSQKGGAEVTVK 106
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
358-464 |
1.55e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 52.46 E-value: 1.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 358 DKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIV 437
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPRPHSGQKSTGLGLAFV 80
|
90 100
....*....|....*....|....*..
gi 544959485 438 SGIINAHRGKLDITSIDSQGLkTILKL 464
Cdd:cd16945 81 QEVAQLHGGRITLRNRPDGVL-AFLTL 106
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
226-467 |
1.84e-08 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 56.96 E-value: 1.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 226 NTVSKELQMKDEKLRKKEEA---RSNWIAGISHDIRTPLSMIIGyAGELEESSSLSNREQEQVSIICNQGIKIRELVNDL 302
Cdd:PRK15347 375 NKVAERTQALAEAKQRAEQAnkrKSEHLTTISHEIRTPLNGVLG-ALELLQNTPLTAEQMDLADTARQCTLSLLAIINNL 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 303 NLVSKLEYNMQALNCDK-------------IRVSAFLREL-ISEFINNNLDNDFYVefdilnediiidaDKKLLKRAISN 368
Cdd:PRK15347 454 LDFSRIESGQMTLSLEEtallplldqamltIQGPAQSKSLtLRTFVGAHVPLYLHL-------------DSLRLRQILVN 520
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 369 LIQNSITHNQQGcNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLksqnglsEAYAKGQNH----GLGILIVSGIINAH 444
Cdd:PRK15347 521 LLGNAVKFTETG-GIRLRVKRHEQQLCFTVEDTGCGIDIQQQQQIF-------TPFYQADTHsqgtGLGLTIASSLAKMM 592
|
250 260
....*....|....*....|...
gi 544959485 445 RGKLDITSIDSQGLKTILKLPLI 467
Cdd:PRK15347 593 GGELTLFSTPGVGSCFSLVLPLN 615
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
362-457 |
6.27e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 50.66 E-value: 6.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 362 LKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQN-HGLGILIVSGI 440
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGgTGLGLAIVKHV 80
|
90
....*....|....*..
gi 544959485 441 INAHRGKLDITSIDSQG 457
Cdd:cd16952 81 MSRHDARLLIASELGKG 97
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
358-465 |
1.39e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 49.84 E-value: 1.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 358 DKKLLKRAISNLIQN---SITHNQQG-CNIRVTSKSDLDF-CYIIVEDDGKGMSQERINSLLksqnglsEAY----AKGQ 428
Cdd:cd16944 1 DTTQISQVLTNILKNaaeAIEGRPSDvGEVRIRVEADQDGrIVLIVCDNGKGFPREMRHRAT-------EPYvttrPKGT 73
|
90 100 110
....*....|....*....|....*....|....*..
gi 544959485 429 nhGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLP 465
Cdd:cd16944 74 --GLGLAIVKKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
362-448 |
1.59e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 49.49 E-value: 1.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 362 LKRAISNLIQNSITHN-QQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLK---SQNGLSEAYakGQNHGLGILIV 437
Cdd:cd16953 1 LGQVLRNLIGNAISFSpPDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDrfyTERPANEAF--GQHSGLGLSIS 78
|
90
....*....|.
gi 544959485 438 SGIINAHRGKL 448
Cdd:cd16953 79 RQIIEAHGGIS 89
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
351-464 |
1.80e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 49.33 E-value: 1.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 351 EDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDlDFCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQnh 430
Cdd:cd16940 3 ADIQVQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKLSAD-DGAVIRVEDNGPGIDEEELEALFERFYRSDGQNYGGS-- 79
|
90 100 110
....*....|....*....|....*....|....
gi 544959485 431 GLGILIVSGIINAHRGKLDITSIDSQGLKTILKL 464
Cdd:cd16940 80 GLGLSIVKRIVELHGGQIFLGNAQGGGLEAWVRL 113
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
362-466 |
3.78e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 48.20 E-value: 3.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 362 LKRAISNLIQNSITHNQQgcNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSQNGL--SEAYAKGqNHGLGILIVSG 439
Cdd:cd16939 1 MARALDNLLRNALRYAHR--TVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLdpSRDRATG-GFGLGLAIVHR 77
|
90 100
....*....|....*....|....*..
gi 544959485 440 IINAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:cd16939 78 VALWHGGHVECDDSELGGACFRLTWPR 104
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
313-466 |
5.24e-07 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 51.83 E-value: 5.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 313 QALNCDKIRVSAFLRELISEFINNNLDNDFYVEFDIlnEDIIIDADkkllkRAIS-----N-LIQNSITH---NQQGCNI 383
Cdd:COG3920 352 QSEDWEGVDLRDYLRELLEPLRDSYGGRGIRIELDG--PDVELPAD-----AAVPlglilNeLVTNALKHaflSGEGGRI 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 384 RVTSKSDLDFCYIIVEDDGKGmsqerinsllksqngLSEAYAKGQNHGLGILIVSGIINAHRGKLDITSidSQGLKTILK 463
Cdd:COG3920 425 RVSWRREDGRLRLTVSDNGVG---------------LPEDVDPPARKGLGLRLIRALVRQLGGTLELDR--PEGTRVRIT 487
|
...
gi 544959485 464 LPL 466
Cdd:COG3920 488 FPL 490
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
358-465 |
1.49e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 46.69 E-value: 1.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 358 DKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKS--QNGLSEAYAKGqNHGLGIL 435
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERfyRVESSRNRASG-GSGLGLA 79
|
90 100 110
....*....|....*....|....*....|
gi 544959485 436 IVSGIINAHRGKLDITSIDSQGLKTILKLP 465
Cdd:cd16946 80 ICHNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
352-465 |
1.68e-06 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 49.97 E-value: 1.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 352 DIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAkgqNHG 431
Cdd:PRK10755 238 DITVQGDATLLRLLLRNLVENAHRYSPEGSTITIKLSQEDGGAVLAVEDEGPGIDESKCGELSKAFVRMDSRYG---GIG 314
|
90 100 110
....*....|....*....|....*....|....*
gi 544959485 432 LGILIVSGIINAHRGKLDITS-IDSQGLKTILKLP 465
Cdd:PRK10755 315 LGLSIVSRITQLHHGQFFLQNrQERSGTRAWVWLP 349
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
356-465 |
2.71e-06 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 45.95 E-value: 2.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 356 DADKklLKRAISNLIQNSITHNQQGCNIR-VTSKSDLDFCYIIVEDDGKGMS---QERInsLLKSQNGLSEAYAKGQNHG 431
Cdd:cd16925 1 DAEK--YERVVLNLLSNAFKFTPDGGRIRcILEKFRLNRFLLTVSDSGPGIPpnlREEI--FERFRQGDGSSTRAHGGTG 76
|
90 100 110
....*....|....*....|....*....|....
gi 544959485 432 LGILIVSGIINAHRGKLDITSIDSQGLKTILKLP 465
Cdd:cd16925 77 LGLSIVKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
252-467 |
9.32e-06 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 48.14 E-value: 9.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 252 GISHDIRTPLSMIIGYAGELEESSSLSNREQEQVSIICNQGIKIRELVND-LNLVSKLEYNMQalncdKIRVSAFLRELI 330
Cdd:PRK13837 456 GIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIISAGARARLIIDQiLAFGRKGERNTK-----PFDLSELVTEIA 530
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 331 SeFINNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSIthnqQGC--NIRVT---SKSDL-------------- 391
Cdd:PRK13837 531 P-LLRVSLPPGVELDFDQDQEPAVVEGNPAELQQVLMNLCSNAA----QAMdgAGRVDislSRAKLrapkvlshgvlppg 605
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544959485 392 DFCYIIVEDDGKGMSQ---ERINSLLKSqnglseayAKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPLI 467
Cdd:PRK13837 606 RYVLLRVSDTGAGIDEavlPHIFEPFFT--------TRAGGTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFDVYLPPS 676
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
244-466 |
1.06e-05 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 48.05 E-value: 1.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 244 EARSNWIAGISHDIRTPLSMIIGYAgELEESSSLSNREQEQVSIICNQGIKIRELVNDLNLVSKLEynMQALncdKIRVS 323
Cdd:PRK10841 445 QSKSMFLATVSHELRTPLYGIIGNL-DLLQTKELPKGVDRLVTAMNNSSSLLLKIISDILDFSKIE--SEQL---KIEPR 518
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 324 AFL-RELISEFINN--------NLDNDFYVEFDILNediIIDADKKLLKRAISNLIQNSITHNQQGCnIRVTSKSDLDFC 394
Cdd:PRK10841 519 EFSpREVINHITANylplvvkkRLGLYCFIEPDVPV---ALNGDPMRLQQVISNLLSNAIKFTDTGC-IVLHVRVDGDYL 594
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 395 YIIVEDDGKGMSQERINSLLKS--QNGlseayAKGQNH----GLGILIVSGIINAHRGklDITSIDSQGLKTI--LKLPL 466
Cdd:PRK10841 595 SFRVRDTGVGIPAKEVVRLFDPffQVG-----TGVQRNfqgtGLGLAICEKLINMMDG--DISVDSEPGMGSQftIRIPL 667
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
228-467 |
1.70e-05 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 47.23 E-value: 1.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 228 VSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSSLSNrEQEQVSIICNQGIKIRELVNDLNLVSK 307
Cdd:PRK10618 432 VNKKLQQAQREYEKNQQARKAFLQNIGDELKQPLQSLAQLAAQLRQTSDEEQ-QQPELDQLAEQSDVLVRLVDNIQLLNM 510
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 308 LEYNMQALNCDKIRVSAFLRELISE------------FINNNLDndfyvefdilNEDIIIdADKKLLKRAISNLIQNSIT 375
Cdd:PRK10618 511 LETQDWKPEQELFSLQDLIDEVLPEvlpaikrkglqlLIHNHLK----------AEQLRI-GDRDALRKILLLLLNYAIT 579
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 376 HNQQG-CNIRVTSKSDLDFCYII-VEDDGKGMSQERINSLlkSQNGLSEAYAK--GQNHGLGILIVSGIINAHRGKLDIT 451
Cdd:PRK10618 580 TTAYGkITLEVDQDESSPDRLTIrILDTGAGVSIKELDNL--HFPFLNQTQGDryGKASGLTFFLCNQLCRKLGGHLTIK 657
|
250
....*....|....*.
gi 544959485 452 SIDSQGLKTILKLPLI 467
Cdd:PRK10618 658 SREGLGTRYSIHLKML 673
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
230-457 |
2.00e-05 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 46.48 E-value: 2.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 230 KELQMKDEKLRKKEE---------ARSNWIAGISHDIRTPL--------SMIIGYAGELEESSS-LSNREQEQVSiicNQ 291
Cdd:PRK09303 126 ELLQLSDELFVLRQEnetlleqlkFKDRVLAMLAHDLRTPLtaaslaleTLELGQIDEDTELKPaLIEQLQDQAR---RQ 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 292 GIKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFinnnldNDFYVEFDI-LNEDIIID-----ADKKLLKRA 365
Cdd:PRK09303 203 LEEIERLITDLLEVGRTRWEALRFNPQKLDLGSLCQEVILEL------EKRWLAKSLeIQTDIPSDlpsvyADQERIRQV 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 366 ISNLIQNSITHNQQGCNI------RVTSKSDldfcyIIVEDDGKGM---SQERI--NSLLKSQNGLSEAYakgqnhGLGI 434
Cdd:PRK09303 277 LLNLLDNAIKYTPEGGTItlsmlhRTTQKVQ-----VSICDTGPGIpeeEQERIfeDRVRLPRDEGTEGY------GIGL 345
|
250 260
....*....|....*....|...
gi 544959485 435 LIVSGIINAHRGKLDITSIDSQG 457
Cdd:PRK09303 346 SVCRRIVRVHYGQIWVDSEPGQG 368
|
|
| HATPase_YehU-like |
cd16956 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-465 |
2.18e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YehU; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Escherichia coli YehU, a HK of the two-component system (TCS) YehU-YehT which is involved in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase); some have a GAF sensor domain while some have a cupin domain.
Pssm-ID: 340432 [Multi-domain] Cd Length: 101 Bit Score: 43.19 E-value: 2.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 365 AISNLIQNSITHNQQG----CNIRVTSKSDLDFCYIIVEDDGKGMSQE-RINSLLKSQNG---------LSEAYakGQNH 430
Cdd:cd16956 5 TLQPIVENAVKHGLSGlldgGRVEITARLDGQHLLLEVEDNGGGMDPDtLARILIRSSNGlglnlvdkrLRQAF--GNDY 82
|
90 100 110
....*....|....*....|....*....|....*
gi 544959485 431 GlgilivsgiinahrgkLDITSIDSQGLKTILKLP 465
Cdd:cd16956 83 G----------------LDIECAPGEGTRITIRLP 101
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
362-465 |
1.15e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 41.23 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 362 LKRAISNLIQNSI-THNQQGCNIRV----TSKSDLDFCYIIVEDDGKGMSQERINSLLksqnglsEAY--AKGQNHGLGI 434
Cdd:cd16920 1 IQQVLINLVRNGIeAMSEGGCERREltirTSPADDRAVTISVKDTGPGIAEEVAGQLF-------DPFytTKSEGLGMGL 73
|
90 100 110
....*....|....*....|....*....|.
gi 544959485 435 LIVSGIINAHRGKLDITSIDSQGLKTILKLP 465
Cdd:cd16920 74 SICRSIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
361-466 |
1.18e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 41.25 E-value: 1.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 361 LLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKGMS---QERINSLLKSQNGLseayakGQNHGLGILIV 437
Cdd:cd16943 3 QLNQVLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDpeiLGRIFDPFFTTKPV------GEGTGLGLSLS 76
|
90 100
....*....|....*....|....*....
gi 544959485 438 SGIINAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:cd16943 77 YRIIQKHGGTIRVASVPGGGTRFTIILPI 105
|
|
| HATPase_LytS-like |
cd16957 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-415 |
1.24e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis LytS and Staphylococcus aureus LytS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), and a GAF sensor domain; most contain a DUF3816 domain.
Pssm-ID: 340433 [Multi-domain] Cd Length: 106 Bit Score: 41.26 E-value: 1.24e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 544959485 365 AISNLIQNSITH----NQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLK 415
Cdd:cd16957 5 ALQVLVENAIRHafpkRKENNEVRVVVKKDQHKVHVSVSDNGQGIPEERLDLLGK 59
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
295-466 |
1.99e-04 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 43.07 E-value: 1.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 295 IRELVNDLNLVSkleYNMQALNCDKIRVSAFLRELISEFINnnlDNDFYVEFDILNEDIIIDADKKL-LKRAISNLIQNS 373
Cdd:COG4585 101 AREALAELRRLV---RGLRPPALDDLGLAAALEELAERLLR---AAGIRVELDVDGDPDRLPPEVELaLYRIVQEALTNA 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 374 ITHNQqGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSllksqnglseayakgqnHGLGILIVSGIINAHRGKLDITSI 453
Cdd:COG4585 175 LKHAG-ATRVTVTLEVDDGELTLTVRDDGVGFDPEAAPG-----------------GGLGLRGMRERAEALGGTLTIGSA 236
|
170
....*....|...
gi 544959485 454 DSQGLKTILKLPL 466
Cdd:COG4585 237 PGGGTRVRATLPL 249
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
362-466 |
2.03e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 40.55 E-value: 2.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 362 LKRAISNLIQNSITHNQQGC-NIRVTSKSDLDFCYII---VEDDGKGMSQERINSLLK--SQ--NGLSEAYakgQNHGLG 433
Cdd:cd16922 1 LRQILLNLLGNAIKFTEEGEvTLRVSLEEEEEDGVQLrfsVEDTGIGIPEEQQARLFEpfSQadSSTTRKY---GGTGLG 77
|
90 100 110
....*....|....*....|....*....|...
gi 544959485 434 ILIVSGIINAHRGKLDITSIDSQGLKTILKLPL 466
Cdd:cd16922 78 LAISKKLVELMGGDISVESEPGQGSTFTFTLPL 110
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-452 |
3.24e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 40.69 E-value: 3.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 368 NLIQNSITHnqqgCN--IRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSQNGLSEAYakgQNHGLGILIVSGIINAHR 445
Cdd:cd16954 44 NLLDNACKW----CLefVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQRGQRLDEQR---PGQGLGLAIAKEIVEQYG 116
|
....*..
gi 544959485 446 GKLDITS 452
Cdd:cd16954 117 GELSLSD 123
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
362-465 |
7.42e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 38.85 E-value: 7.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 362 LKRAISNLIQNSI--THNQQGCNIRVTSKSDLDFCYIIVEDDGKGMS---QERINSLLKSQNGLSEayakGQNHGLGILI 436
Cdd:cd16921 1 LGQVLTNLLGNAIkfRRPRRPPRIEVGAEDVGEEWTFYVRDNGIGIDpeyAEKVFGIFQRLHSREE----YEGTGVGLAI 76
|
90 100
....*....|....*....|....*....
gi 544959485 437 VSGIINAHRGKLDITSIDSQGLKTILKLP 465
Cdd:cd16921 77 VRKIIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
237-408 |
2.16e-03 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 40.69 E-value: 2.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 237 EKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEEsSSLSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALN 316
Cdd:PRK11091 274 DALEKASRDKTTFISTISHELRTPLNGIVGLSRILLD-TELTAEQRKYLKTIHVSAITLGNIFNDIIDMDKMERRKLQLD 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 317 CDKIRVSAFLREL--ISEFINNnlDNDFYVEFDILNE-DIIIDADKKLLKRAISNLIQNSITHNQQG-CNIRVTSKSDLD 392
Cdd:PRK11091 353 NQPIDFTDFLADLenLSGLQAE--QKGLRFDLEPLLPlPHKVITDGTRLRQILWNLISNAVKFTQQGgVTVRVRYEEGDM 430
|
170
....*....|....*.
gi 544959485 393 FCYiIVEDDGKGMSQE 408
Cdd:PRK11091 431 LTF-EVEDSGIGIPED 445
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
366-465 |
2.44e-03 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 40.28 E-value: 2.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 366 ISNLIQNSI--THNQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLksQNGLSeayAKGQNHGLGILIVSGIINA 443
Cdd:PRK11086 438 LGNLIENALeaVGGEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIF--DKGYS---TKGSNRGVGLYLVKQSVEN 512
|
90 100
....*....|....*....|..
gi 544959485 444 HRGKLDITSIDSQGLKTILKLP 465
Cdd:PRK11086 513 LGGSIAVESEPGVGTQFFVQIP 534
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
344-465 |
4.35e-03 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 37.95 E-value: 4.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 344 VEFDILNEDIIIDadKKLLKR---AISNLIQNSITH-------------NQQGcNIRVTSKSDLDFCYIIVEDDGKGMSQ 407
Cdd:cd16916 20 VELVVEGEDTELD--KSVLEKladPLTHLLRNAVDHgieapeerlaagkPPEG-TITLRAEHQGNQVVIEVSDDGRGIDR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544959485 408 ERINSLLKSQNGLSEAYAKG------------------------QNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILK 463
Cdd:cd16916 97 EKIREKAIERGLITADEAATlsddevlnlifapgfstaeqvtdvSGRGVGMDVVKRSIESLGGTIEVESEPGQGTTFTIR 176
|
..
gi 544959485 464 LP 465
Cdd:cd16916 177 LP 178
|
|
| |
