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Full Results
xanthine dehydrogenase family protein molybdopterin-binding subunit [Clostridioides difficile]
Protein Classification
xanthine dehydrogenase family protein molybdopterin-binding subunit ( domain architecture ID 11445946 )
xanthine dehydrogenase family protein molybdopterin-binding subunit is part of an oxidase/dehydrogenase complex acting on one or more of a variety of substrates
List of domain hits
Name
Accession
Description
Interval
E-value
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
2-757
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 803.30
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 2 VN K E V RKI D SE A I VTG KPI YT E D LIF h KDV L TIKLL RSPHA F A K IK N ID IKN AL KVK GVV NIF T YK D V P NYRYSM vgesy 81
Cdd:COG1529 10 IG K P V PRV D GP A K VTG RAR YT D D IRL - PGM L YAAVV RSPHA H A R IK S ID TSA AL ALP GVV AVL T GE D L P GLKFGL ----- 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 82 P EAS P HDQLILE D I VRYVG DE VA IIA AE DER AA IK A MK LIKVEYE VMTPIL D ARES - EGNKI L I HEE DD lfcpfdfglda 160
Cdd:COG1529 84 P GPD P DQPPLAD D K VRYVG EP VA AVV AE TRE AA RD A AE LIKVEYE PLPAVV D PEAA l APGAP L V HEE LP ----------- 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 161 t K N IVSREKMGK GDV EKE F K E S DV I VE HS Y I T QSQ AH CM ME THR A YTYI D TN GRL V V TSAN Q SAYHM RR QVS RALG I P LS 240
Cdd:COG1529 153 - G N VAAEWRGER GDV DAA F A E A DV V VE AT Y T T PRL AH AP ME PRA A VAEW D GD GRL T V WAST Q GPHLV RR ALA RALG L P PE 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 241 KVR A I K P RI GGGFGGK - NIAVT E IY A SFVTWMTK RP A KL IY TREE T F AMTNT RH QMFFDIKI GADK K G N I K A IDMKALNN 319
Cdd:COG1529 232 KVR V I A P DV GGGFGGK l DVYPE E VL A ALAARKLG RP V KL VL TREE D F LADTH RH ATVQRVRL GADK D G K I T A LRHDVVAD 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 320 TGAY GDN G PS V CSESGHNVLPT Y N n V P AIKFDG R T VYTN LV P G GA L RG Y G AT Q GT FAL DC A I DELA HK L N MDP T E IK L K N 399
Cdd:COG1529 312 TGAY ASF G EA V LPLGATMATGP Y A - I P NVRVEA R A VYTN TP P T GA Y RG P G RP Q AA FAL ES A M DELA EE L G MDP V E LR L R N 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 400 I I KKQTEG g IMNF P IR S CA L D EC IIRGKKLI GW D E KYPV - RDIGNN K V R AV G MSVGTH GSG I a NI D MAIVNM R MDE DG TY 478
Cdd:COG1529 391 L I RPGDFP - PTGQ P YD S GR L A EC LEKAAEAF GW G E RRAR p AEARAG K L R GI G VAAYIE GSG G - GG D PESARV R LNP DG SV 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 479 KLFS G SS D L G T G SD T I LAQIAA KA L NTSIDRIS V YT GDTD MC PY DT G AYA S CT T Y V T G N A TI K S AE S L KQ K I L KV A QKK L 558
Cdd:COG1529 469 TVYT G AT D I G Q G HE T V LAQIAA EE L GVPPEDVR V VL GDTD LT PY GG G TGG S RS T A V G G S A VR K A AE K L RE K L L EL A AHL L 548
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 559 DLPID DL ILYED RV C yse DVEKF V L L S EL GKESVG GG nqev L YSSES Y GIQE - SAKP F L A GF AE I E L D KT TGE FK V INYA 637
Cdd:COG1529 549 GADPE DL EFEDG RV R --- VPGRS V S L A EL AAAAYY GG ---- L EATGT Y DPPT y PTYS F G A HV AE V E V D PE TGE VR V LRVV 621
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 638 CST DCG T V M NP A L ARI QVEGGV T QGIG L A M YE DPRHGS DG K L QTS N LLQ Y K VP TKK D IGN I I V D FV DNYE PT G P Y GAK SL 717
Cdd:COG1529 622 AVH DCG R V I NP L L VEG QVEGGV V QGIG Q A L YE ELVYDE DG Q L LNA N FAD Y L VP RAA D VPE I E V I FV ETPD PT N P L GAK GV 701
730 740 750 760
....*....|....*....|....*....|....*....|
gi 544972940 718 GE IVIHTP APAIANA I Y N ATGVRIR E LPIT S EKV YM A MKK 757
Cdd:COG1529 702 GE PGTIGV APAIANA V Y D ATGVRIR D LPIT P EKV LA A LRE 741
Name
Accession
Description
Interval
E-value
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
2-757
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 803.30
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 2 VN K E V RKI D SE A I VTG KPI YT E D LIF h KDV L TIKLL RSPHA F A K IK N ID IKN AL KVK GVV NIF T YK D V P NYRYSM vgesy 81
Cdd:COG1529 10 IG K P V PRV D GP A K VTG RAR YT D D IRL - PGM L YAAVV RSPHA H A R IK S ID TSA AL ALP GVV AVL T GE D L P GLKFGL ----- 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 82 P EAS P HDQLILE D I VRYVG DE VA IIA AE DER AA IK A MK LIKVEYE VMTPIL D ARES - EGNKI L I HEE DD lfcpfdfglda 160
Cdd:COG1529 84 P GPD P DQPPLAD D K VRYVG EP VA AVV AE TRE AA RD A AE LIKVEYE PLPAVV D PEAA l APGAP L V HEE LP ----------- 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 161 t K N IVSREKMGK GDV EKE F K E S DV I VE HS Y I T QSQ AH CM ME THR A YTYI D TN GRL V V TSAN Q SAYHM RR QVS RALG I P LS 240
Cdd:COG1529 153 - G N VAAEWRGER GDV DAA F A E A DV V VE AT Y T T PRL AH AP ME PRA A VAEW D GD GRL T V WAST Q GPHLV RR ALA RALG L P PE 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 241 KVR A I K P RI GGGFGGK - NIAVT E IY A SFVTWMTK RP A KL IY TREE T F AMTNT RH QMFFDIKI GADK K G N I K A IDMKALNN 319
Cdd:COG1529 232 KVR V I A P DV GGGFGGK l DVYPE E VL A ALAARKLG RP V KL VL TREE D F LADTH RH ATVQRVRL GADK D G K I T A LRHDVVAD 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 320 TGAY GDN G PS V CSESGHNVLPT Y N n V P AIKFDG R T VYTN LV P G GA L RG Y G AT Q GT FAL DC A I DELA HK L N MDP T E IK L K N 399
Cdd:COG1529 312 TGAY ASF G EA V LPLGATMATGP Y A - I P NVRVEA R A VYTN TP P T GA Y RG P G RP Q AA FAL ES A M DELA EE L G MDP V E LR L R N 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 400 I I KKQTEG g IMNF P IR S CA L D EC IIRGKKLI GW D E KYPV - RDIGNN K V R AV G MSVGTH GSG I a NI D MAIVNM R MDE DG TY 478
Cdd:COG1529 391 L I RPGDFP - PTGQ P YD S GR L A EC LEKAAEAF GW G E RRAR p AEARAG K L R GI G VAAYIE GSG G - GG D PESARV R LNP DG SV 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 479 KLFS G SS D L G T G SD T I LAQIAA KA L NTSIDRIS V YT GDTD MC PY DT G AYA S CT T Y V T G N A TI K S AE S L KQ K I L KV A QKK L 558
Cdd:COG1529 469 TVYT G AT D I G Q G HE T V LAQIAA EE L GVPPEDVR V VL GDTD LT PY GG G TGG S RS T A V G G S A VR K A AE K L RE K L L EL A AHL L 548
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 559 DLPID DL ILYED RV C yse DVEKF V L L S EL GKESVG GG nqev L YSSES Y GIQE - SAKP F L A GF AE I E L D KT TGE FK V INYA 637
Cdd:COG1529 549 GADPE DL EFEDG RV R --- VPGRS V S L A EL AAAAYY GG ---- L EATGT Y DPPT y PTYS F G A HV AE V E V D PE TGE VR V LRVV 621
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 638 CST DCG T V M NP A L ARI QVEGGV T QGIG L A M YE DPRHGS DG K L QTS N LLQ Y K VP TKK D IGN I I V D FV DNYE PT G P Y GAK SL 717
Cdd:COG1529 622 AVH DCG R V I NP L L VEG QVEGGV V QGIG Q A L YE ELVYDE DG Q L LNA N FAD Y L VP RAA D VPE I E V I FV ETPD PT N P L GAK GV 701
730 740 750 760
....*....|....*....|....*....|....*....|
gi 544972940 718 GE IVIHTP APAIANA I Y N ATGVRIR E LPIT S EKV YM A MKK 757
Cdd:COG1529 702 GE PGTIGV APAIANA V Y D ATGVRIR D LPIT P EKV LA A LRE 741
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
2-752
0e+00
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 651.76
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 2 VN K EVRKI D SE A I VTG KPI YT E D LIF h KDV L TI K LL RSP H A FA K I K N ID IKN A LKVK GV VNI FT YK DVP NYRYSMV G ESY 81
Cdd:PRK09970 3 IG K SIMRV D AI A K VTG RAK YT D D YVM - AGM L YA K YV RSP I A HG K V K S ID TEE A RSLP GV EAV FT WE DVP DIPFPTA G HPW 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 82 PEASP H ---- D QLI L EDI VR YV GD E VA IIA A E DE RA A I KA M KLIKVEYE VMTP I L D ARES - EGNKIL IH EEDD lfcpfdf 156
Cdd:PRK09970 82 SLDPN H rdia D RAL L TRH VR HH GD A VA AVV A R DE LT A E KA L KLIKVEYE ELPV I T D PEAA l AEGAPP IH NGRG ------- 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 157 gldatk N IVSREK M GK G D V EKEF K ES D VI V EHS Y I T QSQA HC M ME THRA Y T Y IDTN GR LVVT S AN Q SAYHM RR Q V SR ALG 236
Cdd:PRK09970 155 ------ N LLKQST M ST G N V QQTI K AA D YQ V QGH Y E T PIVQ HC H ME NVTS Y A Y MEDD GR ITIV S ST Q IPHIV RR V V GQ ALG 228
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 237 IP LS KVR A IKP RI GGGFG G K NIAVT E IY A S F V T W - MTK RP A K LIYT REE T F AM T N TRH QMFF DIK I G ADKK G NI K AIDMK 315
Cdd:PRK09970 229 IP WG KVR V IKP YV GGGFG N K QDVLE E PL A A F L T S k VGG RP V K VSLS REE C F LA T R TRH AFTI DIK M G VNRD G TL K GYSLD 308
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 316 A L N NTGAY GDN G P S VC S ES G HN V LPT Y n NVP A I K FDGR TVYTNL VPG GA L RGYGA T Q GT FA LDCAI D EL A HK L NM DP T E I 395
Cdd:PRK09970 309 V L S NTGAY ASH G H S IA S AG G NK V AYL Y - PRC A Y K YSSK TVYTNL PSA GA M RGYGA P Q VV FA VESML D DA A TA L GI DP V E F 387
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 396 K L K N IIKKQTEGGIMNFP I R S CA L D EC IIR G K K LIG WD EK --- YPVRD ig N N KV R A VG MSVGTHG SG IANIDMA I VNM R - 471
Cdd:PRK09970 388 R L R N AAREGDANPLSGKR I Y S AG L P EC LEK G R K IFE WD KR rae CKNQQ -- G N LR R G VG VACFSYT SG TWPVGLE I AGA R l 465
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 472 - M DE DGT YKLF SG SSDL G T GSDT ILA Q IA A KALNTSIDRIS V Y - T G DTD MC P Y D T GAYAS CTT YV T G N A TI K S A ES LK Q K 549
Cdd:PRK09970 466 l M NQ DGT VQVQ SG ATEI G Q GSDT VFS Q MV A ETVGIPVSDVR V I s T Q DTD VT P F D P GAYAS RQS YV A G P A IR K A A LE LK E K 545
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 550 IL KV A QKK L DLPIDD L ILYEDRVCYSEDV E KFVL L S EL GKESV - GGGNQEVLYSSE S YGIQESAKP F LAG F AEI E L D KTT 628
Cdd:PRK09970 546 IL AH A AVM L HQSAMN L DIIDGHIVVKRPG E PLMS L E EL AMDAY y HPERGGQITAES S IKTTTNPPA F GCT F VDV E V D IAL 625
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 629 GEFKVINYACST D C G TVM NP A LA RI QV E GG VTQ GIG L A MY E ---- D PR hgs D G KLQTS NLL Q YK V PT KK D IGNIIVD FV D 704
Cdd:PRK09970 626 CKVTINRILNVH D S G HIL NP L LA EG QV H GG MGM GIG W A LF E emii D EK --- T G VVRNP NLL D YK L PT MM D LPQLESA FV E 702
730 740 750 760
....*....|....*....|....*....|....*....|....*...
gi 544972940 705 N YEP TGP YG A KSLGE IV I HT PAPAI A NA IYN ATGV R I RE LP I T SEKVY 752
Cdd:PRK09970 703 I YEP QSA YG H KSLGE PP I IS PAPAI R NA VLM ATGV A I NT LP M T PQRLF 750
MoCoBD_1
pfam02738 Molybdopterin cofactor-binding domain;
159-399
5.27e-97
Molybdopterin cofactor-binding domain;
Pssm-ID: 460671 [Multi-domain]
Cd Length: 244
Bit Score: 300.53
E-value: 5.27e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 159 DATK N IV sr EKMG KGDVE KE F K E S D VI VE HS Y I T QS Q A H CM MET HR A YTYI D T - N GRL V V T S AN Q SAYHM RR Q V S R A LGI 237
Cdd:pfam02738 4 EPPN N VA -- FHRE KGDVE AA F A E A D HV VE GE Y R T GR Q E H FY MET RA A LAVP D D e D GRL T V Y S ST Q GPHLV RR L V A R V LGI 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 238 P LS KVR A I K PR I GGGFGGK NIAVT - E IY A SFVTWM T K RP A K LIYT REE TFAM T NT RH QMFFDI K I GADK K G N I K A I D MKA 316
Cdd:pfam02738 82 P EN KVR V I V PR V GGGFGGK TQSYP e E AL A ALAARK T G RP V K WVLD REE DMLA T GH RH PFLIKY K V GADK D G K I L A L D VDL 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 317 LNNT GAY G D NG P S V CSESGHNVLPT Y N n V P AIKF DGR T VYTN LV P G GA L RG Y G AT QG T FAL DCAI DELA HK L N MDP T E IK 396
Cdd:pfam02738 162 YADG GAY A D LS P A V PERALSHLDGP Y K - I P NVRV DGR A VYTN TP P N GA F RG F G RP QG M FAL ERLM DELA EE L G MDP L E LR 240
...
gi 544972940 397 LK N 399
Cdd:pfam02738 241 RR N 243
mam_aldehyde_ox
TIGR02969 aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
16-754
9.30e-46
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain]
Cd Length: 1330
Bit Score: 177.12
E-value: 9.30e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 16 TG KP IY TE D LIFHKDV L TIKLLR S PH A F AKI KN ID IKN AL KVK GVV N I F T YKDVPN yrysm VGESYP E asphd Q L ILE D I 95
Cdd:TIGR02969 590 TG EA IY CD D MPAVDQE L FLTFVT S SR A H AKI VS ID LSE AL SLP GVV D I I T AEHLQD ----- ANTFGT E ----- K L LAT D K 659
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 96 V RY VG DE V AIIA A ED E RA A IK A M K LI K VE Y EVMT P - IL DAR E SEGN K ILIHE E DD L FC pfdfgldatknivsrekmgk G D 174
Cdd:TIGR02969 660 V HC VG QL V CAVI A DS E VQ A KQ A A K HV K IV Y RDLE P l IL TIE E AIQH K SFFEP E RK L EY -------------------- G N 719
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 175 V EKE FK ES D V I V E HSYITQS Q A H CM MET HRAYTYID - TNGRLV V TSAN Q SAYHMRRQ V SRA L GI P LS KV RAIKP R I GG G F 253
Cdd:TIGR02969 720 V DEA FK VV D Q I L E GEIHMGG Q E H FY MET QSMLVVPK g EDQEMD V YVST Q FPKYIQDI V AAT L KL P VN KV MCHVR R V GG A F 799
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 254 GGK -- NIAVTEIYAS F VTWMTK R PAKLIYT R E E TFAM T NT RH QMFFDI K I G ADKK G N I K A I D MKALN N T G AYG D NGPS V C 331
Cdd:TIGR02969 800 GGK vg KTSIMAAITA F AANKHG R AVRCTLE R G E DMLI T GG RH PYLGKY K A G FMND G R I V A L D VEHYS N G G SSL D ESLW V I 879
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 332 s E S G HNVLPTYNNV P AIKFD G RTVY TNL VPGG A L RG Y G AT Q GTFALDCA I D E L A H K LNMD P TEIKLK N II K K qtegg I MN 411
Cdd:TIGR02969 880 - E M G LLKMDNAYKF P NLRCR G WACR TNL PSNT A F RG F G FP Q AGLITEAC I T E V A A K CGLS P EKVRTI N MY K E ----- I DQ 953
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 412 F P IRS caldec I I RG K K L IG - W D E ----- K Y PV R DIGNN K VR A ------ V G MS V --------- G THGS G I A nid M A I V NM 470
Cdd:TIGR02969 954 T P YKQ ------ E I NA K N L FQ c W R E cmaks S Y SE R KVAVE K FN A enywkk R G LA V iplkfpvgl G SVAM G Q A --- A A L V HI 1024
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 471 RM de DG TYKLFS G SSDL G T G SD T ILA Q IAAKA L NTSIDRISVYTGD T DMC P YDTGAYA S CTTYVT G N A TIKSAES L KQKI 550
Cdd:TIGR02969 1025 YL -- DG SVLVTH G GIEM G Q G VH T KMI Q VVSRE L KMPMSNVHLRGTS T ETV P NTNASGG S VVADLN G L A VKDACQT L LKRL 1102
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 551 LKVAQ K KLDLPID D LI lyed RVCYSEDVE kfvl LS EL G ke SVG G gnqevl Y S S ESYGIQESAK PF L ----- A GFA E I E L D 625
Cdd:TIGR02969 1103 EPIIS K NPQGTWK D WA ---- QTAFDQSIS ---- LS AV G -- YFR G ------ Y E S NINWEKGEGH PF E yfvyg A ACS E V E I D 1166
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 626 KT TG EF K V I NYACST D C G TVM NPAL ARI QVEG GVT QG I GL AMY E DPRHGSD G K L QTSNLL QYK V P TKK DI - GNIIVD F VD 704
Cdd:TIGR02969 1167 CL TG DH K N I RTDIVM D V G HSI NPAL DIG QVEG AFI QG M GL YTI E ELSYSPQ G I L YSRGPN QYK I P AIC DI p TELHIS F LP 1246
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 705 NY E PTGP - Y GA K S LGE IVIHTPAP --- AI AN A IYN A TGV R ------ IREL P I T S EK VY MA 754
Cdd:TIGR02969 1247 PS E HSNT l Y SS K G LGE SGVFLGCS vff AI HD A VRA A RQE R glsgpw KLTS P L T P EK IR MA 1306
Ald_Xan_dh_C
smart01008 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ...
16-127
2.27e-31
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain]
Cd Length: 107
Bit Score: 118.00
E-value: 2.27e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 16 TG KPI Y TE D LIF h KDV L TIKLL RSP H A F A K IK N ID IKN A LKVK GVV NIF T Y KDVP NYRYSMVGE sypeas P HDQLILE D I 95
Cdd:smart01008 1 TG EAR Y GD D IRL - PGM L HAAVV RSP V A H A R IK S ID TSA A RAMP GVV AVL T A KDVP GLNDFGPLG ------ P DEPVLAD D K 73
90 100 110
....*....|....*....|....*....|..
gi 544972940 96 VRYVG DE VA IIA AE D E R AA IK A MKLI KVEYE V 127
Cdd:smart01008 74 VRYVG QP VA AVV AE T E E AA RD A AEAV KVEYE E 105
Name
Accession
Description
Interval
E-value
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
2-757
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 803.30
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 2 VN K E V RKI D SE A I VTG KPI YT E D LIF h KDV L TIKLL RSPHA F A K IK N ID IKN AL KVK GVV NIF T YK D V P NYRYSM vgesy 81
Cdd:COG1529 10 IG K P V PRV D GP A K VTG RAR YT D D IRL - PGM L YAAVV RSPHA H A R IK S ID TSA AL ALP GVV AVL T GE D L P GLKFGL ----- 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 82 P EAS P HDQLILE D I VRYVG DE VA IIA AE DER AA IK A MK LIKVEYE VMTPIL D ARES - EGNKI L I HEE DD lfcpfdfglda 160
Cdd:COG1529 84 P GPD P DQPPLAD D K VRYVG EP VA AVV AE TRE AA RD A AE LIKVEYE PLPAVV D PEAA l APGAP L V HEE LP ----------- 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 161 t K N IVSREKMGK GDV EKE F K E S DV I VE HS Y I T QSQ AH CM ME THR A YTYI D TN GRL V V TSAN Q SAYHM RR QVS RALG I P LS 240
Cdd:COG1529 153 - G N VAAEWRGER GDV DAA F A E A DV V VE AT Y T T PRL AH AP ME PRA A VAEW D GD GRL T V WAST Q GPHLV RR ALA RALG L P PE 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 241 KVR A I K P RI GGGFGGK - NIAVT E IY A SFVTWMTK RP A KL IY TREE T F AMTNT RH QMFFDIKI GADK K G N I K A IDMKALNN 319
Cdd:COG1529 232 KVR V I A P DV GGGFGGK l DVYPE E VL A ALAARKLG RP V KL VL TREE D F LADTH RH ATVQRVRL GADK D G K I T A LRHDVVAD 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 320 TGAY GDN G PS V CSESGHNVLPT Y N n V P AIKFDG R T VYTN LV P G GA L RG Y G AT Q GT FAL DC A I DELA HK L N MDP T E IK L K N 399
Cdd:COG1529 312 TGAY ASF G EA V LPLGATMATGP Y A - I P NVRVEA R A VYTN TP P T GA Y RG P G RP Q AA FAL ES A M DELA EE L G MDP V E LR L R N 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 400 I I KKQTEG g IMNF P IR S CA L D EC IIRGKKLI GW D E KYPV - RDIGNN K V R AV G MSVGTH GSG I a NI D MAIVNM R MDE DG TY 478
Cdd:COG1529 391 L I RPGDFP - PTGQ P YD S GR L A EC LEKAAEAF GW G E RRAR p AEARAG K L R GI G VAAYIE GSG G - GG D PESARV R LNP DG SV 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 479 KLFS G SS D L G T G SD T I LAQIAA KA L NTSIDRIS V YT GDTD MC PY DT G AYA S CT T Y V T G N A TI K S AE S L KQ K I L KV A QKK L 558
Cdd:COG1529 469 TVYT G AT D I G Q G HE T V LAQIAA EE L GVPPEDVR V VL GDTD LT PY GG G TGG S RS T A V G G S A VR K A AE K L RE K L L EL A AHL L 548
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 559 DLPID DL ILYED RV C yse DVEKF V L L S EL GKESVG GG nqev L YSSES Y GIQE - SAKP F L A GF AE I E L D KT TGE FK V INYA 637
Cdd:COG1529 549 GADPE DL EFEDG RV R --- VPGRS V S L A EL AAAAYY GG ---- L EATGT Y DPPT y PTYS F G A HV AE V E V D PE TGE VR V LRVV 621
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 638 CST DCG T V M NP A L ARI QVEGGV T QGIG L A M YE DPRHGS DG K L QTS N LLQ Y K VP TKK D IGN I I V D FV DNYE PT G P Y GAK SL 717
Cdd:COG1529 622 AVH DCG R V I NP L L VEG QVEGGV V QGIG Q A L YE ELVYDE DG Q L LNA N FAD Y L VP RAA D VPE I E V I FV ETPD PT N P L GAK GV 701
730 740 750 760
....*....|....*....|....*....|....*....|
gi 544972940 718 GE IVIHTP APAIANA I Y N ATGVRIR E LPIT S EKV YM A MKK 757
Cdd:COG1529 702 GE PGTIGV APAIANA V Y D ATGVRIR D LPIT P EKV LA A LRE 741
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
2-752
0e+00
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 651.76
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 2 VN K EVRKI D SE A I VTG KPI YT E D LIF h KDV L TI K LL RSP H A FA K I K N ID IKN A LKVK GV VNI FT YK DVP NYRYSMV G ESY 81
Cdd:PRK09970 3 IG K SIMRV D AI A K VTG RAK YT D D YVM - AGM L YA K YV RSP I A HG K V K S ID TEE A RSLP GV EAV FT WE DVP DIPFPTA G HPW 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 82 PEASP H ---- D QLI L EDI VR YV GD E VA IIA A E DE RA A I KA M KLIKVEYE VMTP I L D ARES - EGNKIL IH EEDD lfcpfdf 156
Cdd:PRK09970 82 SLDPN H rdia D RAL L TRH VR HH GD A VA AVV A R DE LT A E KA L KLIKVEYE ELPV I T D PEAA l AEGAPP IH NGRG ------- 154
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 157 gldatk N IVSREK M GK G D V EKEF K ES D VI V EHS Y I T QSQA HC M ME THRA Y T Y IDTN GR LVVT S AN Q SAYHM RR Q V SR ALG 236
Cdd:PRK09970 155 ------ N LLKQST M ST G N V QQTI K AA D YQ V QGH Y E T PIVQ HC H ME NVTS Y A Y MEDD GR ITIV S ST Q IPHIV RR V V GQ ALG 228
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 237 IP LS KVR A IKP RI GGGFG G K NIAVT E IY A S F V T W - MTK RP A K LIYT REE T F AM T N TRH QMFF DIK I G ADKK G NI K AIDMK 315
Cdd:PRK09970 229 IP WG KVR V IKP YV GGGFG N K QDVLE E PL A A F L T S k VGG RP V K VSLS REE C F LA T R TRH AFTI DIK M G VNRD G TL K GYSLD 308
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 316 A L N NTGAY GDN G P S VC S ES G HN V LPT Y n NVP A I K FDGR TVYTNL VPG GA L RGYGA T Q GT FA LDCAI D EL A HK L NM DP T E I 395
Cdd:PRK09970 309 V L S NTGAY ASH G H S IA S AG G NK V AYL Y - PRC A Y K YSSK TVYTNL PSA GA M RGYGA P Q VV FA VESML D DA A TA L GI DP V E F 387
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 396 K L K N IIKKQTEGGIMNFP I R S CA L D EC IIR G K K LIG WD EK --- YPVRD ig N N KV R A VG MSVGTHG SG IANIDMA I VNM R - 471
Cdd:PRK09970 388 R L R N AAREGDANPLSGKR I Y S AG L P EC LEK G R K IFE WD KR rae CKNQQ -- G N LR R G VG VACFSYT SG TWPVGLE I AGA R l 465
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 472 - M DE DGT YKLF SG SSDL G T GSDT ILA Q IA A KALNTSIDRIS V Y - T G DTD MC P Y D T GAYAS CTT YV T G N A TI K S A ES LK Q K 549
Cdd:PRK09970 466 l M NQ DGT VQVQ SG ATEI G Q GSDT VFS Q MV A ETVGIPVSDVR V I s T Q DTD VT P F D P GAYAS RQS YV A G P A IR K A A LE LK E K 545
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 550 IL KV A QKK L DLPIDD L ILYEDRVCYSEDV E KFVL L S EL GKESV - GGGNQEVLYSSE S YGIQESAKP F LAG F AEI E L D KTT 628
Cdd:PRK09970 546 IL AH A AVM L HQSAMN L DIIDGHIVVKRPG E PLMS L E EL AMDAY y HPERGGQITAES S IKTTTNPPA F GCT F VDV E V D IAL 625
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 629 GEFKVINYACST D C G TVM NP A LA RI QV E GG VTQ GIG L A MY E ---- D PR hgs D G KLQTS NLL Q YK V PT KK D IGNIIVD FV D 704
Cdd:PRK09970 626 CKVTINRILNVH D S G HIL NP L LA EG QV H GG MGM GIG W A LF E emii D EK --- T G VVRNP NLL D YK L PT MM D LPQLESA FV E 702
730 740 750 760
....*....|....*....|....*....|....*....|....*...
gi 544972940 705 N YEP TGP YG A KSLGE IV I HT PAPAI A NA IYN ATGV R I RE LP I T SEKVY 752
Cdd:PRK09970 703 I YEP QSA YG H KSLGE PP I IS PAPAI R NA VLM ATGV A I NT LP M T PQRLF 750
PRK09800
PRK09800 putative hypoxanthine oxidase; Provisional
2-758
0e+00
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain]
Cd Length: 956
Bit Score: 559.06
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 2 VN K EVR K I D SEAI V TG KP I Y T ED LI f HK D VLT IK L LRSPHA F A K I KNI D IKN A LKVK GVV NIF T YKDV P NYR Y SMV G E S Y 81
Cdd:PRK09800 172 IG K HYP K T D AAKM V QA KP C Y V ED RV - TA D ACV IK M LRSPHA H A L I THL D VSK A EALP GVV HVI T HLNC P DIY Y TPG G Q S A 250
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 82 PE A SP H D QLILEDIV R Y VGD E VA IIA AE D E RA A IK A M KLI K VEYEV MT P ILDAR E SEG - NKILI H E E --------- D D L - 150
Cdd:PRK09800 251 PE P SP L D RRMFGKKM R H VGD R VA AVV AE S E EI A LE A L KLI D VEYEV LK P VMSID E AMA e DAPVV H D E pvvyvagap D T L e 330
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 151 ------------- FCP F DF G LDAT KNI VSREKMGK GD VE K E F KES DVI V E HS Y ITQSQAH C MM ETH RAY T YI D TN g RLV V 217
Cdd:PRK09800 331 ddnshaaqrgehm IIN F PI G SRPR KNI AASIHGHI GD MD K G F ADA DVI I E RT Y NSTQAQQ C PT ETH ICF T RM D GD - RLV I 409
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 218 TSAN Q SAY H M RRQV S R AL G IPLS KV RA IK P R I GGGFG G K NIAVT E IYASFV T WM T K RP AKLI YTREE T F AMTNT RH QMFF 297
Cdd:PRK09800 410 HAST Q VPW H L RRQV A R LV G MKQH KV HV IK E R V GGGFG S K QDILL E EVCAWA T CV T G RP VLFR YTREE E F IANTS RH VAKV 489
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 298 DI K I GA D K K G NIK A ID M KALN NTG A YG DNGPS V CSESGHNV LP T Y -- N NV pai K F DGR T V Y T N LV P G GA LR GYGA TQ G T F 375
Cdd:PRK09800 490 TV K L GA K K D G RLT A VK M DFRA NTG P YG NHSLT V PCNGPALS LP L Y pc D NV --- D F QVT T Y Y S N IC P N GA YQ GYGA PK G N F 566
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 376 A LDC A ID ELA HK L NM D PT EI KLK N IIKKQT E -------- G G IMNFPI --- R SCAL D E CIIR G KKL I G W DEKY P VR di G NN 444
Cdd:PRK09800 567 A ITM A LA ELA EQ L QI D QL EI IER N RVHEGQ E lkilgaig E G KAPTSV psa A SCAL E E ILRQ G REM I Q W SSPK P QN -- G DW 644
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 445 KV r AV G MSVGTHG SGI AN ID M A IVNMRMDE DGT YKLF SG SS D L GTG S DT ILAQI AA KA L NTSIDRIS V YT GDTD MCPY D T 524
Cdd:PRK09800 645 HI - GR G VAIIMQK SGI PD ID Q A NCMIKLES DGT FIVH SG GA D I GTG L DT VVTKL AA EV L HCPPQDVH V IS GDTD HALF D K 723
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 525 GAYAS CT T YVT GNA TIKS AE S L KQ KIL KVAQKK L DL P ID D LI L YEDR V CYSEDV E kf V LLSELGKESVG G GNQEV L YSSE 604
Cdd:PRK09800 724 GAYAS SG T CFS GNA ARLA AE N L RE KIL FHGAQM L GE P VA D VQ L ATPG V VRGKKG E -- V SFGDIAHKGET G TGFGS L VGTG 801
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 605 SY GIQES A K P FL A G FAE IELDKT TGE FKVINYACST DCGT VM NP A LA RI Q VE G GVTQG IG LA M Y E DPRHGSD G KLQ T SN L 684
Cdd:PRK09800 802 SY ITPDF A F P YG A N FAE VAVNTR TGE IRLDKFYALL DCGT PV NP E LA LG Q IY G ATLRA IG HS M S E EIIYDAE G HPL T RD L 881
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544972940 685 LQ Y KV P T kkd IG N I IV DF ---- V DNYEPT GP Y GAKS LG EI VIHTP APAIA N AI YN A T G VRI RE LPI T S EK VYM A MK K L 758
Cdd:PRK09800 882 RS Y GA P K --- IG D I PR DF ravl V PSDDKV GP F GAKS IS EI GVNGA APAIA T AI HD A C G IWL RE WHF T P EK ILT A LE K I 956
MoCoBD_1
pfam02738 Molybdopterin cofactor-binding domain;
159-399
5.27e-97
Molybdopterin cofactor-binding domain;
Pssm-ID: 460671 [Multi-domain]
Cd Length: 244
Bit Score: 300.53
E-value: 5.27e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 159 DATK N IV sr EKMG KGDVE KE F K E S D VI VE HS Y I T QS Q A H CM MET HR A YTYI D T - N GRL V V T S AN Q SAYHM RR Q V S R A LGI 237
Cdd:pfam02738 4 EPPN N VA -- FHRE KGDVE AA F A E A D HV VE GE Y R T GR Q E H FY MET RA A LAVP D D e D GRL T V Y S ST Q GPHLV RR L V A R V LGI 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 238 P LS KVR A I K PR I GGGFGGK NIAVT - E IY A SFVTWM T K RP A K LIYT REE TFAM T NT RH QMFFDI K I GADK K G N I K A I D MKA 316
Cdd:pfam02738 82 P EN KVR V I V PR V GGGFGGK TQSYP e E AL A ALAARK T G RP V K WVLD REE DMLA T GH RH PFLIKY K V GADK D G K I L A L D VDL 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 317 LNNT GAY G D NG P S V CSESGHNVLPT Y N n V P AIKF DGR T VYTN LV P G GA L RG Y G AT QG T FAL DCAI DELA HK L N MDP T E IK 396
Cdd:pfam02738 162 YADG GAY A D LS P A V PERALSHLDGP Y K - I P NVRV DGR A VYTN TP P N GA F RG F G RP QG M FAL ERLM DELA EE L G MDP L E LR 240
...
gi 544972940 397 LK N 399
Cdd:pfam02738 241 RR N 243
MoCoBD_2
pfam20256 Molybdopterin cofactor-binding domain;
425-695
1.85e-75
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain]
Cd Length: 282
Bit Score: 245.52
E-value: 1.85e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 425 RGKK L IGW DE KYPVRDIG N -- N KV R AV G MSVGTH GSG IA -- NIDM A IVNM R MDE DG TYKLFS G SSDL G T G SD T I LAQIAA 500
Cdd:pfam20256 1 KALE L SDY DE RRAEQAEF N rg N RK R GI G IAPYVE GSG LG pg ALNQ A GALV R LNP DG SVTVYT G GTEM G Q G LE T K LAQIAA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 501 K AL NTSIDRIS V YT GDTD MC P YDT G AY AS CT T Y V T GNA TIKS AE S L KQKI LK V A QKK L DLPID DL I l Y ED RVC Y SEDVEK 580
Cdd:pfam20256 81 E AL GIPPEDVR V VE GDTD TV P NGG G TG AS RS T D V G GNA VLLA AE K L RERL LK I A AHL L EASPE DL E - F ED GKV Y VKGDPR 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 581 F V LLS EL GKESV G G G NQ ev L YSSES Y GIQESAK --------- P FL A GF AE I E L D KT TGE FK V IN Y ACST DCG T V M NPA LA 651
Cdd:pfam20256 160 S V TFA EL AAAAY G E G VG -- L SATGF Y TPPDDET gqgppfayy P YG A HA AE V E V D PE TGE VR V LR Y VAVH DCG R V I NPA IV 237
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 544972940 652 RI Q V EGG VT QGIGLA MY E DPRHGS DG K L Q T SN L LQ YK V PT KK DI 695
Cdd:pfam20256 238 EG Q I EGG FV QGIGLA LM E ELVYDE DG Q L L T AS L MD YK I PT AA DI 281
PLN02906
PLN02906 xanthine dehydrogenase
15-754
8.44e-69
xanthine dehydrogenase
Pssm-ID: 215491 [Multi-domain]
Cd Length: 1319
Bit Score: 246.92
E-value: 8.44e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 15 VTG KPI Y TE D LIFHKDV L TIK L LR S PHAF A K I KN ID IKN A LKVK G VVN IF TY KDVP nyrysmv G ESYPEASP HD Q - L ILE 93
Cdd:PLN02906 578 VTG EAE Y AD D IPMPPNT L HAA L VL S TKPH A R I LS ID DSE A KSSP G FAG IF LA KDVP ------- G DNMIGPVV HD E e L FAT 650
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 94 D I V RY VG DEVAIIA A EDERA A IK A MKLI KVEYE VMTP IL DAR E SE gnkilihe E DDL F C P F dfgldatkniv SREKMG KG 173
Cdd:PLN02906 651 D V V TC VG QVIGVVV A DTQEN A KA A ARKV KVEYE ELPA IL SIE E AI -------- E AGS F H P N ----------- TERRLE KG 711
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 174 DVE KE F KES dviv EHSY I TQSQAHCMMET H ray T Y IDT N GR LV V TS ANQSAY HM ---------- RRQ V SRA LG I P L SKV R 243
Cdd:PLN02906 712 DVE LC F ASG ---- QCDR I IEGEVQMGGQE H --- F Y LEP N SS LV W TS DSGNEV HM isstqapqkh QKY V AHV LG L P M SKV V 784
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 244 AIKP RIGGGFGGK NI -- A VTEIY A SFVTWMTK RP A KL IYT R EETFAM T NT RH QMFFDI K I G ADKK G N I K A I D MKAL NN T G 321
Cdd:PLN02906 785 CKTK RIGGGFGGK ET rs A FIAAA A AVPAYLLN RP V KL TLD R DVDMMI T GQ RH AFLGKY K V G FTNE G K I L A L D LEIY NN G G 864
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 322 AYG D NGPS V CSESGHNVLPT Y n NV P AIKFD G RTVY TN LVPGG A L RG Y G AT QG TFALDCA I DEL A HK LN MD P T EI KLK N I i 401
Cdd:PLN02906 865 NSL D LSGA V LERAMFHSDNV Y - EI P NVRIV G NVCF TN FPSNT A F RG F G GP QG MLITENW I QRI A VE LN KS P E EI REM N F - 942
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 402 kk Q T EG GIMNFP -- IRS C A L DEC iirgkklig WDE KYPVR D I ----------- GN N KVRAV G MSVGTHGS GI A ------ N 462
Cdd:PLN02906 943 -- Q G EG SVTHYG qv LQH C T L PQL --------- WDE LKVSC D F lkrreevdefn AK N RWKKR G VAMVPTKF GI S fttkfm N 1011
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 463 IDM A I V NMRM de DGT YKLFS G SSDL G T G SD T IL AQ I AA K A L N TSIDRISVYTGD TD MC P YDTGAY AS CTTYVT G N A TIKS 542
Cdd:PLN02906 1012 QAG A L V HVYT -- DGT VLVTH G GVEM G Q G LH T KV AQ V AA S A F N IPLSSVFISETS TD KV P NASPTA AS ASSDMY G A A VLDA 1089
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 543 A E SL K QKILK VA Q K KLDLPIDD L IL yedr V CY SEDVE ---- K F VLLSEL G KESVG G - GN Q evl YSSES YG iqesakpfl A 617
Cdd:PLN02906 1090 C E QI K ARMEP VA S K LNFSSFAE L VT ---- A CY FQRID lsah G F YITPDI G FDWKT G k GN P --- FNYFT YG --------- A 1153
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 618 G FAE I E L D KT TG E F KVINYACST D C G TVM NPA LARI Q V EG GVT QG I G LAMY E DPRH G SD ------- G K L Q T SNLLQ YK V P 690
Cdd:PLN02906 1154 A FAE V E I D TL TG D F HTRRVDIVM D L G YSI NPA IDIG Q I EG AFV QG L G WVAL E ELKW G DA ahkwirp G S L F T CGPGT YK I P 1233
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 691 TKK DI G nii VD F ------- VD N ye P TGPYGA K SL GE IVIHTP A P --- AI AN AI YN A ------ T G VRIREL P I T S E KVY MA 754
Cdd:PLN02906 1234 SVN DI P --- FK F nvsllkg AP N -- P KAIHSS K AV GE PPFFLA A S vff AI KD AI KA A raevgl H G WFPLDT P A T P E RIR MA 1308
mam_aldehyde_ox
TIGR02969 aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
16-754
9.30e-46
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain]
Cd Length: 1330
Bit Score: 177.12
E-value: 9.30e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 16 TG KP IY TE D LIFHKDV L TIKLLR S PH A F AKI KN ID IKN AL KVK GVV N I F T YKDVPN yrysm VGESYP E asphd Q L ILE D I 95
Cdd:TIGR02969 590 TG EA IY CD D MPAVDQE L FLTFVT S SR A H AKI VS ID LSE AL SLP GVV D I I T AEHLQD ----- ANTFGT E ----- K L LAT D K 659
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 96 V RY VG DE V AIIA A ED E RA A IK A M K LI K VE Y EVMT P - IL DAR E SEGN K ILIHE E DD L FC pfdfgldatknivsrekmgk G D 174
Cdd:TIGR02969 660 V HC VG QL V CAVI A DS E VQ A KQ A A K HV K IV Y RDLE P l IL TIE E AIQH K SFFEP E RK L EY -------------------- G N 719
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 175 V EKE FK ES D V I V E HSYITQS Q A H CM MET HRAYTYID - TNGRLV V TSAN Q SAYHMRRQ V SRA L GI P LS KV RAIKP R I GG G F 253
Cdd:TIGR02969 720 V DEA FK VV D Q I L E GEIHMGG Q E H FY MET QSMLVVPK g EDQEMD V YVST Q FPKYIQDI V AAT L KL P VN KV MCHVR R V GG A F 799
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 254 GGK -- NIAVTEIYAS F VTWMTK R PAKLIYT R E E TFAM T NT RH QMFFDI K I G ADKK G N I K A I D MKALN N T G AYG D NGPS V C 331
Cdd:TIGR02969 800 GGK vg KTSIMAAITA F AANKHG R AVRCTLE R G E DMLI T GG RH PYLGKY K A G FMND G R I V A L D VEHYS N G G SSL D ESLW V I 879
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 332 s E S G HNVLPTYNNV P AIKFD G RTVY TNL VPGG A L RG Y G AT Q GTFALDCA I D E L A H K LNMD P TEIKLK N II K K qtegg I MN 411
Cdd:TIGR02969 880 - E M G LLKMDNAYKF P NLRCR G WACR TNL PSNT A F RG F G FP Q AGLITEAC I T E V A A K CGLS P EKVRTI N MY K E ----- I DQ 953
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 412 F P IRS caldec I I RG K K L IG - W D E ----- K Y PV R DIGNN K VR A ------ V G MS V --------- G THGS G I A nid M A I V NM 470
Cdd:TIGR02969 954 T P YKQ ------ E I NA K N L FQ c W R E cmaks S Y SE R KVAVE K FN A enywkk R G LA V iplkfpvgl G SVAM G Q A --- A A L V HI 1024
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 471 RM de DG TYKLFS G SSDL G T G SD T ILA Q IAAKA L NTSIDRISVYTGD T DMC P YDTGAYA S CTTYVT G N A TIKSAES L KQKI 550
Cdd:TIGR02969 1025 YL -- DG SVLVTH G GIEM G Q G VH T KMI Q VVSRE L KMPMSNVHLRGTS T ETV P NTNASGG S VVADLN G L A VKDACQT L LKRL 1102
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 551 LKVAQ K KLDLPID D LI lyed RVCYSEDVE kfvl LS EL G ke SVG G gnqevl Y S S ESYGIQESAK PF L ----- A GFA E I E L D 625
Cdd:TIGR02969 1103 EPIIS K NPQGTWK D WA ---- QTAFDQSIS ---- LS AV G -- YFR G ------ Y E S NINWEKGEGH PF E yfvyg A ACS E V E I D 1166
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 626 KT TG EF K V I NYACST D C G TVM NPAL ARI QVEG GVT QG I GL AMY E DPRHGSD G K L QTSNLL QYK V P TKK DI - GNIIVD F VD 704
Cdd:TIGR02969 1167 CL TG DH K N I RTDIVM D V G HSI NPAL DIG QVEG AFI QG M GL YTI E ELSYSPQ G I L YSRGPN QYK I P AIC DI p TELHIS F LP 1246
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 705 NY E PTGP - Y GA K S LGE IVIHTPAP --- AI AN A IYN A TGV R ------ IREL P I T S EK VY MA 754
Cdd:TIGR02969 1247 PS E HSNT l Y SS K G LGE SGVFLGCS vff AI HD A VRA A RQE R glsgpw KLTS P L T P EK IR MA 1306
PLN00192
PLN00192 aldehyde oxidase
2-691
1.41e-40
aldehyde oxidase
Pssm-ID: 215096 [Multi-domain]
Cd Length: 1344
Bit Score: 161.04
E-value: 1.41e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 2 V NKEVR K IDSEAIVT G KPI Y TE D LIFH K DV L TIKLLR S PHAF A KI K N I DI K NA L KVK GV VNIF T Y KD V P ---- N yrysm V 77
Cdd:PLN00192 579 V GEPIK K VGAALQAS G EAV Y VD D IPSP K NC L YGAFIY S TKPL A RV K G I KF K SN L VPQ GV LAVI T F KD I P kggq N ----- I 653
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 78 G ESYPEAS ph DQ L ILEDIV R YV G DEV A IIA A EDERA A IK A MK L IK VEY EV --- MT PIL DARESEGNKI L I h E EDDLFC P f 154
Cdd:PLN00192 654 G SKTIFGP -- EP L FADEVT R CA G QRI A LVV A DTQKH A DM A AN L AV VEY DT enl EP PIL TVEDAVKRSS L F - E VPPFLY P - 729
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 155 dfgldat K NI vsrekmgk GD VE K EFK E S D VIVEHSY I T - Q SQ AHCM MET HR A YTYI D TNGRL VV T S AN Q SAYHMRRQVS R 233
Cdd:PLN00192 730 ------- K PV -------- GD IS K GMA E A D HKILSAE I K l G SQ YYFY MET QT A LALP D EDNCI VV Y S ST Q CPEYVHSVIA R 794
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 234 A LGIP LSK VR A I KP R I GGGFGGK NIAVTEIYA -- SFVTWMTK RP AKLIYT R EETFA M TNT RH Q M FFDIKI G ADKK G N I K A 311
Cdd:PLN00192 795 C LGIP EHN VR V I TR R V GGGFGGK AVKSMPVAT ac ALAAFKLQ RP VRMYLN R KTDMI M AGG RH P M KITYSV G FKSD G K I T A 874
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 312 IDMKA L N N T G AYG D NG P SV cses GH N V --- L PT Y n NVP A IK FD GRTVY TNL VPGG A L R GY G AT QG TFALDCA I DEL A HK L 388
Cdd:PLN00192 875 LHLDI L I N A G ISP D IS P IM ---- PR N I iga L KK Y - DWG A LS FD IKVCK TNL SSRS A M R AP G EV QG SYIAEAI I EHV A ST L 949
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 389 N MD PTEIKLK N I -------- IKKQTE G GIMNFPIR S C aldeciirgkklig WD ----- EKYPV R DI ------ GN NK VRAV 449
Cdd:PLN00192 950 S MD VDSVRKI N L htyeslkl FYGDSA G EPSEYTLP S I -------------- WD klass SEFKQ R TE mvkefn RS NK WKKR 1015
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 450 G M S V -- GT H G sgianidmai V NM R ------- MDE DG TYKLFS G SSDL G T G SD T ILA Q I AA KA L NTS -------- I D R I S V 512
Cdd:PLN00192 1016 G I S R vp IV H E ---------- V ML R ptpgkvs ILS DG SIAVEV G GIEI G Q G LW T KVK Q M AA FG L GMI kcdggedl L D K I R V 1085
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 513 YTG DT ------ DMCPYD T GAYA SC ttyvtg N A TIKSAES L KQKI lkvaqkkld L PI DDLILYEDR vcyse D V EKFV L L S E 586
Cdd:PLN00192 1086 IQS DT lsmiqg GFTAGS T TSES SC ------ E A VRLCCVI L VERL --------- K PI KERLQEQMG ----- S V TWDM L I S Q 1145
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 587 LGKE SV G ggnqev L YS S ES Y GIQE S AKPF L --- A GFA E I E L D KT TGE FKVINYACST DCG TVM NPA LARI Q V EG GVT QGI 663
Cdd:PLN00192 1146 AYMQ SV N ------ L SA S SY Y TPDP S SMEY L nyg A AVS E V E V D LL TGE TTILRSDIIY DCG QSL NPA VDLG Q I EG AFV QGI 1219
730 740
....*....|....*....|....*...
gi 544972940 664 G LA M Y E DPRHG SDG KLQ T SNLLQ YK V PT 691
Cdd:PLN00192 1220 G FF M L E EYTTN SDG LVV T DGTWT YK I PT 1247
Ald_Xan_dh_C
smart01008 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ...
16-127
2.27e-31
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain]
Cd Length: 107
Bit Score: 118.00
E-value: 2.27e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 16 TG KPI Y TE D LIF h KDV L TIKLL RSP H A F A K IK N ID IKN A LKVK GVV NIF T Y KDVP NYRYSMVGE sypeas P HDQLILE D I 95
Cdd:smart01008 1 TG EAR Y GD D IRL - PGM L HAAVV RSP V A H A R IK S ID TSA A RAMP GVV AVL T A KDVP GLNDFGPLG ------ P DEPVLAD D K 73
90 100 110
....*....|....*....|....*....|..
gi 544972940 96 VRYVG DE VA IIA AE D E R AA IK A MKLI KVEYE V 127
Cdd:smart01008 74 VRYVG QP VA AVV AE T E E AA RD A AEAV KVEYE E 105
Ald_Xan_dh_C
pfam01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
16-127
1.95e-28
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
Pssm-ID: 426197 [Multi-domain]
Cd Length: 107
Bit Score: 109.63
E-value: 1.95e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544972940 16 TG KPI Y TE D l I FHKDV L TIKLL RS PH A F AKI KN ID IKN AL KVK GVV NIF T Y KD V P nyrysm V G ESYPEAS P H D Q L ILE D I 95
Cdd:pfam01315 1 TG EAV Y VD D - I PAPGN L YGAFV RS TI A H AKI VS ID TSA AL ALP GVV AVI T A KD L P ------ G G NYNIGPI P L D P L FAT D K 73
90 100 110
....*....|....*....|....*....|..
gi 544972940 96 VR Y VG DEV A IIA A E DE RA A IK A M KL I KVEYE V 127
Cdd:pfam01315 74 VR H VG QPI A AVV A D DE ET A RR A A KL V KVEYE E 105
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
