|
Name |
Accession |
Description |
Interval |
E-value |
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
5-214 |
7.93e-111 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 319.14 E-value: 7.93e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEIRNMVGYLPQD 83
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLGPGMYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVlKQPQKLRRRIGYLPQE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:cd03264 81 FGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAG 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 544973757 164 LDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNG 214
Cdd:cd03264 161 LDPEERIRFRNLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
5-219 |
8.69e-95 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 279.26 E-value: 8.69e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEIRNMVGYLPQ 82
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSLTVEPGeIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVaRDPAEVRRRIGYVPQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:COG1131 81 EPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTS 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 163 GLDPEERIRFRNLLCEIAND-RIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:COG1131 161 GLDPEARRELWELLRELAAEgKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDEL 218
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
5-219 |
9.04e-75 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 228.59 E-value: 9.04e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEIRNMVGYLPQ 82
Cdd:COG4555 2 IEVENLSKKYGKVPALKDVSFTAKDGeITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVrKEPREARRQIGVLPD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:COG4555 82 ERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTN 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 163 GLDPEERIRFRNLLCEIAN-DRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:COG4555 162 GLDVMARRLLREILRALKKeGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDEL 219
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
5-266 |
2.24e-71 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 221.91 E-value: 2.24e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIenTKEIRNMVGYLPQD 83
Cdd:COG4152 2 LELKGLTKRFGDKTAVDDVSFTVPKGeIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPL--DPEDRRRIGYLPEE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:COG4152 80 RGLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 164 LDPEERIRFRNLLCE-IANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEALAKLAEGKVYSIEVDkKDIENIKS 242
Cdd:COG4152 160 LDPVNVELLKDVIRElAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGRNTLRLEAD-GDAGWLRA 238
|
250 260
....*....|....*....|....
gi 544973757 243 RFIVIGMLTHGGKATLRIISDDKP 266
Cdd:COG4152 239 LPGVTVVEEDGDGAELKLEDGADA 262
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
5-210 |
8.64e-69 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 211.10 E-value: 8.64e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEIRNMVGYLPQ 82
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGeIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIkKEPEEVKRRIGYLPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVYkamDYLavlsdiplrkrrkiiakllskvnltnyqnmkvkSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:cd03230 81 EPSLYENLTVR---ENL---------------------------------KLSGGMKQRLALAQALLHDPELLILDEPTS 124
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 544973757 163 GLDPEERIRFRNLLCEIAND-RIVILSTHIVGDIEATCENVAILDSGKV 210
Cdd:cd03230 125 GLDPESRREFWELLRELKKEgKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| GldA_ABC_ATP |
TIGR03522 |
gliding motility-associated ABC transporter ATP-binding subunit GldA; Members of this protein ... |
3-263 |
4.31e-60 |
|
gliding motility-associated ABC transporter ATP-binding subunit GldA; Members of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldA is an ABC transporter ATP-binding protein (pfam00005) linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae and Cytophaga hutchinsonii. Knockouts of GldA abolish the gliding phenotype. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Bacteroidetes with members of this protein family appear to have all of the genes associated with gliding motility.
Pssm-ID: 132561 [Multi-domain] Cd Length: 301 Bit Score: 193.07 E-value: 4.31e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEIRNMVGYL 80
Cdd:TIGR03522 1 MSIRVSSLTKLYGTQNALDEVSFEAQKGrIVGFLGPNGAGKSTTMKIITGYLPPDSGSVQVCGEDVlQNPKEVQRNIGYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:TIGR03522 81 PEHNPLYLDMYVREYLQFIAGIYGMKGQLLKQRVEEMIELVGLRPEQHKKIGQLSKGYRQRVGLAQALIHDPKVLILDEP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 161 TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEALAKLAEGKVYSIEVDKK-DIEN 239
Cdd:TIGR03522 161 TTGLDPNQLVEIRNVIKNIGKDKTIILSTHIMQEVEAICDRVIIINKGKIVADKKLDELSAANKKQVIEVEFEEQiDLQL 240
|
250 260
....*....|....*....|....*
gi 544973757 240 IKS-RFIVIGMLTHGGKATLRIISD 263
Cdd:TIGR03522 241 FETlEEISSVKNTGGNTWKLTFETP 265
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
7-216 |
6.04e-59 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 187.33 E-value: 6.04e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQ--ALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEIRNMVGYLPQ 82
Cdd:cd03263 3 IRNLTKTYKKGTkpAVDDLSLNVYKGeIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIrTDRKAARQSLGYCPQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:cd03263 83 FDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTS 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 544973757 163 GLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGST 216
Cdd:cd03263 163 GLDPASRRAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSP 216
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
5-219 |
2.62e-56 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 180.64 E-value: 2.62e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEIRNMVGYLPQ 82
Cdd:cd03265 1 IEVENLVKKYGDFEAVRGVSFRVRRGeIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVvREPREVRRRIGIVFQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:cd03265 81 DLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTI 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 163 GLDPEERIRFRNLLCEI--ANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:cd03265 161 GLDPQTRAHVWEYIEKLkeEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
5-214 |
2.37e-55 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 177.79 E-value: 2.37e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQD 83
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGeIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEALRRIGALIEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVYKAMDYLAVLsdipLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:cd03268 81 PGFYPNLTARENLRLLARL----LGIRKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNG 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 544973757 164 LDPEERIRFRNLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGKVIYNG 214
Cdd:cd03268 157 LDPDGIKELRELILSLRDQGItVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
5-214 |
1.07e-54 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 176.32 E-value: 1.07e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIenTKEIRNMVGYLPQD 83
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGeIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPL--DIAARNRIGYLPEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:cd03269 79 RGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSG 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 544973757 164 LDPEERIRFRNLLCEIA-NDRIVILSTHIVGDIEATCENVAILDSGKVIYNG 214
Cdd:cd03269 159 LDPVNVELLKDVIRELArAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
12-263 |
7.71e-51 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 169.49 E-value: 7.71e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 12 KRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEIRNMVGYLPQDFSMYPN 89
Cdd:TIGR01188 1 KVYGDFKAVDGVNFKVREGeVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDVvREPRKVRRSIGIVPQYASVDED 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 90 MTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEER 169
Cdd:TIGR01188 81 LTGRENLEMMGRLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 170 IRFRNLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGKVIYNGSTEALAKLAEGKV-YSIEVDKKDIENIKSRFIVI 247
Cdd:TIGR01188 161 RAIWDYIRALKEEGVtILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLGKDTlESRPRDIQSLKVEVSMLIAE 240
|
250
....*....|....*.
gi 544973757 248 GMLTHGGKATLRIISD 263
Cdd:TIGR01188 241 LGETGLGLLAVTVDSD 256
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
5-219 |
1.07e-49 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 164.04 E-value: 1.07e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF-GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI--ENTKEIRNMVGYL 80
Cdd:COG1122 1 IELENLSFSYpGGTPALDDVSLSIEKGEFvAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDItkKNLRELRRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDfsmyP-----NMTVYKamdylavlsDI---------PLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQ 146
Cdd:COG1122 81 FQN----PddqlfAPTVEE---------DVafgpenlglPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAG 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 544973757 147 ALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:COG1122 148 VLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKtVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREV 221
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
9-211 |
5.02e-48 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 159.22 E-value: 5.02e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 9 NLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMY 87
Cdd:cd03259 5 GLSKTYGSVRALDDLSLTVEPGeFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERRNIGMVFQDYALF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 88 PNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE 167
Cdd:cd03259 85 PHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAK 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 544973757 168 ERIRFRNLLCEI--ANDRIVILSTHIVGDIEATCENVAILDSGKVI 211
Cdd:cd03259 165 LREELREELKELqrELGITTIYVTHDQEEALALADRIAVMNEGRIV 210
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-217 |
4.34e-47 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 157.94 E-value: 4.34e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIentKEIRNMVGY 79
Cdd:COG1121 3 MMPAIELENLTVSYGGRPVLEDVSLTIPPGeFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPP---RRARRRIGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYPN--MTV--------YKAMDYLAVLSdiplRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALI 149
Cdd:COG1121 80 VPQRAEVDWDfpITVrdvvlmgrYGRRGLFRRPS----RADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 150 HNPRVLIVDEPTAGLDPEERIRFRNLLCEI-ANDRIVILSTHIVGDIEATCENVAILDsGKVIYNGSTE 217
Cdd:COG1121 156 QDPDLLLLDEPFAGVDAATEEALYELLRELrREGKTILVVTHDLGAVREYFDRVLLLN-RGLVAHGPPE 223
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
5-246 |
9.55e-47 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 157.13 E-value: 9.55e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN--TKEIRNMVGYLP 81
Cdd:COG1120 2 LEAENLSVGYGGRPVLDDVSLSLPPGEVtALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASlsRRELARRIAYVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QDFSMYPNMTVYkamDYLAvLSDIPLRKR--------RKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPR 153
Cdd:COG1120 82 QEPPAPFGLTVR---ELVA-LGRYPHLGLfgrpsaedREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 154 VLIVDEPTAGLDPEERIRFRNLLCEIAND--RIVILSTHivgDIE---ATCENVAILDSGKVIYNGSTEAL---AKLAEg 225
Cdd:COG1120 158 LLLLDEPTSHLDLAHQLEVLELLRRLARErgRTVVMVLH---DLNlaaRYADRLVLLKDGRIVAQGPPEEVltpELLEE- 233
|
250 260
....*....|....*....|.
gi 544973757 226 kVYSIEVDKKDIENIKSRFIV 246
Cdd:COG1120 234 -VYGVEARVIEDPVTGRPLVL 253
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-196 |
1.71e-46 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 156.79 E-value: 1.71e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRF----GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEntkEIRN 75
Cdd:COG1116 4 AAPALELRGVSKRFptggGGVTALDDVSLTVAAGEFvALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVT---GPGP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 76 MVGYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVL 155
Cdd:COG1116 81 DRGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVL 160
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 544973757 156 IVDEPTAGLDPEERIRFRNLLCEI--ANDRIVILSTHivgDIE 196
Cdd:COG1116 161 LMDEPFGALDALTRERLQDELLRLwqETGKTVLFVTH---DVD 200
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
5-190 |
2.71e-46 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 154.96 E-value: 2.71e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFG----KKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEI------ 73
Cdd:cd03255 1 IELKNLSKTYGgggeKVQALKGVSLSIEKGEFvAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKelaafr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 74 RNMVGYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPR 153
Cdd:cd03255 81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160
|
170 180 190
....*....|....*....|....*....|....*....
gi 544973757 154 VLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTH 190
Cdd:cd03255 161 IILADEPTGNLDSETGKEVMELLRELNKEAgtTIVVVTH 199
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
3-198 |
3.95e-46 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 154.17 E-value: 3.95e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE-IRNMVGYL 80
Cdd:COG4133 1 MMLEAENLSCRRGERLLFSGLSFTLAAGeALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREdYRRRLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRkiIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:COG4133 81 GHADGLKPELTVRENLRFWAALYGLRADREA--IDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEP 158
|
170 180 190
....*....|....*....|....*....|....*....
gi 544973757 161 TAGLDPEERIRFRNLLCE-IANDRIVILSTHIVGDIEAT 198
Cdd:COG4133 159 FTALDAAGVALLAELIAAhLARGGAVLLTTHQPLELAAA 197
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
5-219 |
7.50e-46 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 161.22 E-value: 7.50e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF-----GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-----ENTKEI 73
Cdd:COG1123 261 LEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGeTLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLtklsrRSLREL 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 74 RNMVGYLPQD-FSMY-PNMTVYKAMDY-LAVLSDIPLRKRRKIIAKLLSKVNL-TNYQNMKVKSLSGGMNRRLGIAQALI 149
Cdd:COG1123 341 RRRVQMVFQDpYSSLnPRMTVGDIIAEpLRLHGLLSRAERRERVAELLERVGLpPDLADRYPHELSGGQRQRVAIARALA 420
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 544973757 150 HNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR----IVIlsTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:COG1123 421 LEPKLLILDEPTSALDVSVQAQILNLLRDLQRELgltyLFI--SHDLAVVRYIADRVAVMYDGRIVEDGPTEEV 492
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-221 |
3.03e-45 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 152.83 E-value: 3.03e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENT-----KEIR 74
Cdd:COG1127 2 SEPMIEVRNLTKSFGDRVVLDGVSLDVPRGeILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLsekelYELR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 75 NMVGYLPQD---FSmypNMTVYkamDYLAV----LSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQA 147
Cdd:COG1127 82 RRIGMLFQGgalFD---SLTVF---ENVAFplreHTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARA 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 148 LIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIaNDRI---VILSTHIVGDIEATCENVAILDSGKVIYNGSTEALAK 221
Cdd:COG1127 156 LALDPEILLYDEPTAGLDPITSAVIDELIREL-RDELgltSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLA 231
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
7-214 |
7.89e-45 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 151.15 E-value: 7.89e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTkeiRNMVGYLPQDFS 85
Cdd:cd03235 2 VEDLTVSYGGHPVLEDVSFEVKPGEFlAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKE---RKRIGYVPQRRS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 86 M---YPnMTVYK----AMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVD 158
Cdd:cd03235 79 IdrdFP-ISVRDvvlmGLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLD 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 159 EPTAGLDPEERIRFRNLLCEI-ANDRIVILSTHIVGDIEATCENVAILDsGKVIYNG 214
Cdd:cd03235 158 EPFAGVDPKTQEDIYELLRELrREGMTILVVTHDLGLVLEYFDRVLLLN-RTVVASG 213
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
7-209 |
2.14e-44 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 149.92 E-value: 2.14e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRF--GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI--ENTKEIRNMVGYLP 81
Cdd:cd03225 2 LKNLSFSYpdGARPALDDISLTIKKGEFvLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLtkLSLKELRRKVGLVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QD-FSMYPNMTVYkamDYLA---VLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIV 157
Cdd:cd03225 82 QNpDDQFFGPTVE---EEVAfglENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 544973757 158 DEPTAGLDPEERIRFRNLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGK 209
Cdd:cd03225 159 DEPTAGLDPAGRRELLELLKKLKAEGKtIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
5-209 |
2.49e-44 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 148.49 E-value: 2.49e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI----ENTKEIRNMVGY 79
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGeIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLtdleDELPPLRRRIGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYPNMTVYKamdylavlsdiplrkrrkiiakllskvNLTnyqnmkvKSLSGGMNRRLGIAQALIHNPRVLIVDE 159
Cdd:cd03229 81 VFQDFALFPHLTVLE---------------------------NIA-------LGLSGGQQQRVALARALAMDPDVLLLDE 126
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 544973757 160 PTAGLDPEERIRFRNLLCEI-ANDRI-VILSTHIVGDIEATCENVAILDSGK 209
Cdd:cd03229 127 PTSALDPITRREVRALLKSLqAQLGItVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
5-219 |
5.41e-44 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 151.88 E-value: 5.41e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEIRNMVGYLPQ 82
Cdd:PRK13537 8 IDFRNVEKRYGDKLVVDGLSFHVQRGEcFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVpSRARHARQRVGVVPQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:PRK13537 88 FDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTT 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544973757 163 GLDPEER----IRFRNLLceiANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK13537 168 GLDPQARhlmwERLRSLL---ARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHAL 225
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
5-219 |
1.73e-43 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 148.67 E-value: 1.73e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF-GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNM---V 77
Cdd:COG3638 3 LELRNLSKRYpGGTPALDDVSLEIERGEFvALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTalRGRALRRLrrrI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GYLPQDFSMYPNMTVYK-----AMDYL----AVLSDIPLRKRRKIIAkLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQAL 148
Cdd:COG3638 83 GMIFQQFNLVPRLSVLTnvlagRLGRTstwrSLLGLFPPEDRERALE-ALERVGLADKAYQRADQLSGGQQQRVAIARAL 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 544973757 149 IHNPRVLIVDEPTAGLDPE--ERIrfRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:COG3638 162 VQEPKLILADEPVASLDPKtaRQV--MDLLRRIAREDgiTVVVNLHQVDLARRYADRIIGLRDGRVVFDGPPAEL 234
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-190 |
1.97e-43 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 147.88 E-value: 1.97e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKK----QALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE--- 72
Cdd:COG1136 1 MSPLLELRNLTKSYGTGegevTALRGVSLSIEAGEFvAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSErel 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 73 --IRN-MVGYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALI 149
Cdd:COG1136 81 arLRRrHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALV 160
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 544973757 150 HNPRVLIVDEPTAGLDPEERIRFRNLLCEIAND--RIVILSTH 190
Cdd:COG1136 161 NRPKLILADEPTGNLDSKTGEEVLELLRELNRElgTTIVMVTH 203
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
5-214 |
1.47e-42 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 145.20 E-value: 1.47e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKK----QALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEIRNMVG 78
Cdd:cd03266 2 ITADALTKRFRDVkktvQAVDGVSFTVKPGeVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVvKEPAEARRRLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 79 YLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVD 158
Cdd:cd03266 82 FVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLD 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 159 EPTAGLDPEERIRFRNLLCEI-ANDRIVILSTHIVGDIEATCENVAILDSGKVIYNG 214
Cdd:cd03266 162 EPTTGLDVMATRALREFIRQLrALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
7-209 |
2.27e-42 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 142.77 E-value: 2.27e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN--TKEIRNMVGYLPQd 83
Cdd:cd00267 2 IENLSFRYGGRTALDNVSLTLKAGeIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKlpLEELRRRIGYVPQ- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 fsmypnmtvykamdylavlsdiplrkrrkiiakllskvnltnyqnmkvksLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:cd00267 81 --------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTSG 110
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 544973757 164 LDPEERIRFRNLLCEIAND-RIVILSTHIVGDIEATCENVAILDSGK 209
Cdd:cd00267 111 LDPASRERLLELLRELAEEgRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
5-196 |
2.40e-42 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 144.92 E-value: 2.40e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFG----KKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIentKEIRNMVGY 79
Cdd:cd03293 1 LEVRNVSKTYGggggAVTALEDISLSVEEGEFvALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPV---TGPGPDRGY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDE 159
Cdd:cd03293 78 VFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDE 157
|
170 180 190
....*....|....*....|....*....|....*....
gi 544973757 160 PTAGLDPEERIRFRNLLCEI--ANDRIVILSTHivgDIE 196
Cdd:cd03293 158 PFSALDALTREQLQEELLDIwrETGKTVLLVTH---DID 193
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
5-219 |
2.97e-42 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 145.40 E-value: 2.97e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFG-KKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN--TKEIRNM---V 77
Cdd:cd03256 1 IEVENLSKTYPnGKKALKDVSLSINPGeFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKlkGKALRQLrrqI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GYLPQDFSMYPNMTVYK--------AMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALI 149
Cdd:cd03256 81 GMIFQQFNLIERLSVLEnvlsgrlgRRSTWRSLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALM 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 150 HNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:cd03256 161 QQPKLILADEPVASLDPASSRQVMDLLKRINREEgiTVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
7-215 |
3.95e-42 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 144.46 E-value: 3.95e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIeNTKEIRNmVGYLPQDFS 85
Cdd:TIGR03740 3 TKNLSKRFGKQTAVNNISLTVPKNsVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPW-TRKDLHK-IGSLIESPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 86 MYPNMTVYKAMDYLAVLSDIPLRKrrkiIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLD 165
Cdd:TIGR03740 81 LYENLTARENLKVHTTLLGLPDSR----IDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKLLILDEPTNGLD 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 544973757 166 PEERIRFRNLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGKVIYNGS 215
Cdd:TIGR03740 157 PIGIQELRELIRSFPEQGItVILSSHILSEVQQLADHIGIISEGVLGYQGK 207
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
5-221 |
4.65e-42 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 144.57 E-value: 4.65e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE-----IRNMVG 78
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGeILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEaelyrLRRRMG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 79 YLPQDFSMYPNMTVYKAMDY-LAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIV 157
Cdd:cd03261 81 MLFQSGALFDSLTVFENVAFpLREHTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLY 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 158 DEPTAGLDP------EERIrfRNLLCEIANDRIVIlsTHIVGDIEATCENVAILDSGKVIYNGSTEALAK 221
Cdd:cd03261 161 DEPTAGLDPiasgviDDLI--RSLKKELGLTSIMV--THDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
6-214 |
2.75e-40 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 138.34 E-value: 2.75e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 6 AVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN--TKEIRNMVGYLPQ 82
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGeIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASlsPKELARKIAYVPQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 dfsmypnmtvykAMDYLAVLSdipLRKRRkiiakllskvnltnyqnmkVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:cd03214 81 ------------ALELLGLAH---LADRP-------------------FNELSGGERQRVLLARALAQEPPILLLDEPTS 126
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 163 GLDPEERIRFRNLLCEIANDR--IVILSTHivgDIEAT---CENVAILDSGKVIYNG 214
Cdd:cd03214 127 HLDIAHQIELLELLRRLARERgkTVVMVLH---DLNLAaryADRVILLKDGRIVAQG 180
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
3-219 |
8.66e-40 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 141.51 E-value: 8.66e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEIRNMVGYL 80
Cdd:PRK13536 40 VAIDLAGVSKSYGDKAVVNGLSFTVASGeCFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVpARARLARARIGVV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:PRK13536 120 PQFDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEP 199
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544973757 161 TAGLDPEER----IRFRNLLceiANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK13536 200 TTGLDPHARhliwERLRSLL---ARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHAL 259
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
5-214 |
1.05e-39 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 138.02 E-value: 1.05e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF----GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN-----TKEIR 74
Cdd:cd03257 2 LEVKNLSVSFptggGSVKALDDVSFSIKKGeTLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKlsrrlRKIRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 75 NMVGYLPQD--FSMYPNMTVYKAMD--YLAVLSDIPLRKRRKIIAKLLSKVNL-TNYQNMKVKSLSGGMNRRLGIAQALI 149
Cdd:cd03257 82 KEIQMVFQDpmSSLNPRMTIGEQIAepLRIHGKLSKKEARKEAVLLLLVGVGLpEEVLNRYPHELSGGQRQRVAIARALA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 150 HNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNG 214
Cdd:cd03257 162 LNPKLLIADEPTSALDVSVQAQILDLLKKLQEELglTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
5-221 |
1.37e-39 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 137.95 E-value: 1.37e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK--EIRNM-VGYL 80
Cdd:cd03219 1 LEVRGLTKRFGGLVALDDVSFSVRPGeIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPphEIARLgIGRT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFSMYPNMTVYKAMDyLAV--------LSDIPLRKRRKIIAK---LLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALI 149
Cdd:cd03219 81 FQIPRLFPELTVLENVM-VAAqartgsglLLARARREEREARERaeeLLERVGLADLADRPAGELSYGQQRRLEIARALA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544973757 150 HNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGKVIYNGSTEALAK 221
Cdd:cd03219 160 TDPKLLLLDEPAAGLNPEETEELAELIRELRERGItVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRN 232
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
9-219 |
1.53e-39 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 146.81 E-value: 1.53e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 9 NLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE-NTKEIRNMVGYLPQDFSM 86
Cdd:NF033858 271 GLTMRFGDFTAVDHVSFRIRRGeIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDaGDIATRRRVGYMSQAFSL 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 87 YPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDP 166
Cdd:NF033858 351 YGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDP 430
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 167 EERIRFRNLLCEIA-NDRIVI-LSTHIVGdiEAT-CENVAILDSGKVIYNGSTEAL 219
Cdd:NF033858 431 VARDMFWRLLIELSrEDGVTIfISTHFMN--EAErCDRISLMHAGRVLASDTPAAL 484
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
5-224 |
6.68e-39 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 136.86 E-value: 6.68e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKK----QALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN--TKEIRNMV 77
Cdd:COG1124 2 LEVRNLSVSYGQGgrrvPVLKDVSLEVAPGeSFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRrrRKAFRRRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GYLPQDF--SMYPNMTVYKAMDYLAVLSDIPLRKRRkiIAKLLSKVNLT-NYQNMKVKSLSGGMNRRLGIAQALIHNPRV 154
Cdd:COG1124 82 QMVFQDPyaSLHPRHTVDRILAEPLRIHGLPDREER--IAELLEQVGLPpSFLDRYPHQLSGGQRQRVAIARALILEPEL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 155 LIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNGSTEALAKLAE 224
Cdd:COG1124 160 LLLDEPTSALDVSVQAEILNLLKDLREERglTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGPK 231
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
5-219 |
1.20e-38 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 136.81 E-value: 1.20e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGK-----KQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-----ENTKEI 73
Cdd:TIGR04521 1 IKLKNVSYIYQPgtpfeKKALDDVSLTIEDGEFvAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDItakkkKKLKDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 74 RNMVGYLPQdfsmYPNM-----TVYKamdylavlsDI---------PLRKRRKIIAKLLSKVNLTnyQNMKVKS---LSG 136
Cdd:TIGR04521 81 RKKVGLVFQ----FPEHqlfeeTVYK---------DIafgpknlglSEEEAEERVKEALELVGLD--EEYLERSpfeLSG 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 137 GMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEI--ANDRIVILSTHIVGDIEATCENVAILDSGKVIYNG 214
Cdd:TIGR04521 146 GQMRRVAIAGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLhkEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDG 225
|
....*
gi 544973757 215 STEAL 219
Cdd:TIGR04521 226 TPREV 230
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
5-220 |
2.24e-38 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 134.98 E-value: 2.24e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENT---KEIRNMVGYL 80
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGeIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLpmhKRARLGIGYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFSMYPNMTVykAMDYLAVLSDIPLRK--RRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVD 158
Cdd:cd03218 81 PQEASIFRKLTV--EENILAVLEIRGLSKkeREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLD 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544973757 159 EPTAGLDPEERIRFRNLLCEIANDRIVILST-HIVGDIEATCENVAILDSGKVIYNGSTEALA 220
Cdd:cd03218 159 EPFAGVDPIAVQDIQKIIKILKDRGIGVLITdHNVRETLSITDRAYIIYEGKVLAEGTPEEIA 221
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
5-190 |
2.60e-38 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 134.41 E-value: 2.60e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF-GKKQALDNINLEIDSGMFGLL-GRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE-----IRNMV 77
Cdd:COG2884 2 IRFENVSKRYpGGREALSDVSLEIEKGEFVFLtGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRreipyLRRRI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GYLPQDFSMYPNMTVYkamDYLAvlsdIPLR---KRRKIIAK----LLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIH 150
Cdd:COG2884 82 GVVFQDFRLLPDRTVY---ENVA----LPLRvtgKSRKEIRRrvreVLDLVGLSDKAKALPHELSGGEQQRVAIARALVN 154
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 544973757 151 NPRVLIVDEPTAGLDPEERIRFRNLLCEIaNDR--IVILSTH 190
Cdd:COG2884 155 RPELLLADEPTGNLDPETSWEIMELLEEI-NRRgtTVLIATH 195
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-219 |
2.02e-37 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 135.61 E-value: 2.02e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMK-IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK-EIRNmV 77
Cdd:COG3842 1 MAMPaLELENVSKRYGDVTALDDVSLSIEPGeFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPpEKRN-V 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GYLPQDFSMYPNMTVY-------KAMDylavlsdIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIH 150
Cdd:COG3842 80 GMVFQDYALFPHLTVAenvafglRMRG-------VPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAP 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 544973757 151 NPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR-I-VILSTHivgDIE---ATCENVAILDSGKVIYNGSTEAL 219
Cdd:COG3842 153 EPRVLLLDEPLSALDAKLREEMREELRRLQRELgItFIYVTH---DQEealALADRIAVMNDGRIEQVGTPEEI 223
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
2-221 |
2.10e-37 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 132.46 E-value: 2.10e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 2 EMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN---TKEIRNMV 77
Cdd:COG1137 1 MMTLEAENLVKSYGKRTVVKDVSLEVNQGeIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHlpmHKRARLGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GYLPQDFSMYPNMTVYKAMdyLAVL--SDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVL 155
Cdd:COG1137 81 GYLPQEASIFRKLTVEDNI--LAVLelRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFI 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 156 IVDEPTAGLDPEERIRFRNLLCEIANDRIVILST-HIVGDIEATCENVAILDSGKVIYNGSTEALAK 221
Cdd:COG1137 159 LLDEPFAGVDPIAVADIQKIIRHLKERGIGVLITdHNVRETLGICDRAYIISEGKVLAEGTPEEILN 225
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
3-219 |
3.46e-37 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 134.89 E-value: 3.46e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCG------VPienTKEiRN 75
Cdd:COG1118 1 MSIEVRNISKRFGSFTLLDDVSLEIASGeLVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGrdlftnLP---PRE-RR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 76 mVGYLPQDFSMYPNMTVYkamDYLAV-LSDIPLRK--RRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNP 152
Cdd:COG1118 77 -VGFVFQHYALFPHMTVA---ENIAFgLRVRPPSKaeIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEP 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 544973757 153 RVLIVDEPTAGLD----PEERIRFRNLLCEIanDRIVILSTHivgDIE---ATCENVAILDSGKVIYNGSTEAL 219
Cdd:COG1118 153 EVLLLDEPFGALDakvrKELRRWLRRLHDEL--GGTTVFVTH---DQEealELADRVVVMNQGRIEQVGTPDEV 221
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
5-219 |
3.89e-37 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 131.53 E-value: 3.89e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLL-----SKTEGSIHMCGVPI----ENTKEIR 74
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEiTALIGPSGCGKSTLLRLLNRLNdlipgAPDEGEVLLDGKDIydldVDVLELR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 75 NMVGYLPQDFSMYPnMTVYKAMDYLAVLSDIPLRKRRK-IIAKLLSKVNLTNY--QNMKVKSLSGGMNRRLGIAQALIHN 151
Cdd:cd03260 81 RRVGMVFQKPNPFP-GSIYDNVAYGLRLHGIKLKEELDeRVEEALRKAALWDEvkDRLHALGLSGGQQQRLCLARALANE 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 152 PRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:cd03260 160 PEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
|
|
| LPS_export_lptB |
TIGR04406 |
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ... |
7-220 |
9.97e-37 |
|
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 130.86 E-value: 9.97e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENT---KEIRNMVGYLPQ 82
Cdd:TIGR04406 4 AENLIKSYKKRKVVNDVSLSVKSGeIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHLpmhERARLGIGYLPQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVYKamDYLAVL---SDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDE 159
Cdd:TIGR04406 84 EASIFRKLTVEE--NIMAVLeirKDLDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILLDE 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 160 PTAGLDPEERIRFRNLLCEIANDRIVILST-HIVGDIEATCENVAILDSGKVIYNGSTEALA 220
Cdd:TIGR04406 162 PFAGVDPIAVGDIKKIIKHLKERGIGVLITdHNVRETLDICDRAYIISDGKVLAEGTPAEIV 223
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
5-265 |
1.01e-36 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 132.90 E-value: 1.01e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF-------G--------------KKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHM 62
Cdd:COG4586 2 IEVENLSKTYrvyekepGlkgalkglfrreyrEVEAVDDISFTIEPGeIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 63 CG-VPIENTKEIRNMVGylpqdFSM------YPNMTVYKAMDYLAVLSDIP---LRKRRKIIAKLLskvNLTNYQNMKVK 132
Cdd:COG4586 82 LGyVPFKRRKEFARRIG-----VVFgqrsqlWWDLPAIDSFRLLKAIYRIPdaeYKKRLDELVELL---DLGELLDTPVR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 133 SLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKV 210
Cdd:COG4586 154 QLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERgtTILLTSHDMDDIEALCDRVIVIDHGRI 233
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 211 IYNGSTEAL-AKLAEGKVYSIEVDKK-DIENIKSRFIVIGmlTHGGKATLRIISDDK 265
Cdd:COG4586 234 IYDGSLEELkERFGPYKTIVLELAEPvPPLELPRGGEVIE--REGNRVRLEVDPRES 288
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
5-214 |
1.28e-36 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 130.53 E-value: 1.28e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSK---------------------RFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHM 62
Cdd:cd03267 1 IEVSNLSKsyrvyskepgligslkslfkrKYREVEALKGISFTIEKGeIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 63 CG-VPIENTKEIRNMVGY-LPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNR 140
Cdd:cd03267 81 AGlVPWKRRKKFLRRIGVvFGQKTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRM 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 141 RLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNG 214
Cdd:cd03267 161 RAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERgtTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
5-219 |
1.79e-36 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 130.11 E-value: 1.79e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGK-KQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENT--KEIRNM---V 77
Cdd:TIGR02315 2 LEVENLSKVYPNgKQALKNINLNINPGEFvAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLrgKKLRKLrrrI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GYLPQDFSMYPNMTVYK--------AMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALI 149
Cdd:TIGR02315 82 GMIFQHYNLIERLTVLEnvlhgrlgYKPTWRSLLGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIARALA 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 150 HNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:TIGR02315 162 QQPDLILADEPIASLDPKTSKQVMDYLKRINKEDgiTVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSEL 233
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
5-217 |
5.22e-36 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 131.35 E-value: 5.22e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKK----QALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNM- 76
Cdd:COG1135 2 IELENLSKTFPTKggpvTALDDVSLTIEKGeIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTalSERELRAAr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 --VGYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRV 154
Cdd:COG1135 82 rkIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKV 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544973757 155 LIVDEPTAGLDPE--ERIrfRNLLCEIaNDRI---VILSTH---IVGDIeatCENVAILDSGKVIYNGSTE 217
Cdd:COG1135 162 LLCDEATSALDPEttRSI--LDLLKDI-NRELgltIVLITHemdVVRRI---CDRVAVLENGRIVEQGPVL 226
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
5-210 |
3.42e-35 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 126.08 E-value: 3.42e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK--EIRNMVGYLP 81
Cdd:COG4619 1 LELEGLSFRVGGKPILSPVSLTLEAGECvAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPppEWRRQVAYVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QDFSMYPNmTVYKAMDYLAVLSDIPLRkrRKIIAKLLSKVNLTN-YQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:COG4619 81 QEPALWGG-TVRDNLPFPFQLRERKFD--RERALELLERLGLPPdILDKPVERLSGGERQRLALIRALLLQPDVLLLDEP 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 544973757 161 TAGLDPEERIRFRNLLCEIAN--DRIVILSTHIVGDIEATCENVAILDSGKV 210
Cdd:COG4619 158 TSALDPENTRRVEELLREYLAeeGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
5-219 |
3.67e-35 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 126.54 E-value: 3.67e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFG----KKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE-----IR 74
Cdd:cd03258 2 IELKNVSKVFGdtggKVTALKDVSLSVPKGeIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGkelrkAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 75 NMVGYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRV 154
Cdd:cd03258 82 RRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKV 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 155 LIVDEPTAGLDPEERIRFRNLLCEIaNDRI---VILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:cd03258 162 LLCDEATSALDPETTQSILALLRDI-NRELgltIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEV 228
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1-218 |
4.59e-35 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 127.08 E-value: 4.59e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK--EIRNM- 76
Cdd:COG0411 1 SDPLLEVRGLTKRFGGLVAVDDVSLEVERGeIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPphRIARLg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 VGYLPQDFSMYPNMTVY----------KAMDYLAVLSDIP--LRKRRKIIAK---LLSKVNLTNYQNMKVKSLSGGMNRR 141
Cdd:COG0411 81 IARTFQNPRLFPELTVLenvlvaaharLGRGLLAALLRLPraRREEREARERaeeLLERVGLADRADEPAGNLSYGQQRR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 142 LGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRI--VILSTHIVGDIEATCENVAILDSGKVIYNGSTEA 218
Cdd:COG0411 161 LEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGitILLIEHDMDLVMGLADRIVVLDFGRVIAEGTPAE 239
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
3-219 |
6.51e-35 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 125.91 E-value: 6.51e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLP 81
Cdd:cd03296 1 MSIEVRNVSKRFGDFVALDDVSLDIPSGeLVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQERNVGFVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QDFSMYPNMTVYkamDYLAVLSDIPLRKRR----KIIAK---LLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRV 154
Cdd:cd03296 81 QHYALFRHMTVF---DNVAFGLRVKPRSERppeaEIRAKvheLLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKV 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 155 LIVDEPTAGLDPEERIRFRNLLCEIaNDRIVILSTHIVGDIEATCE---NVAILDSGKVIYNGSTEAL 219
Cdd:cd03296 158 LLLDEPFGALDAKVRKELRRWLRRL-HDELHVTTVFVTHDQEEALEvadRVVVMNKGRIEQVGTPDEV 224
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
7-214 |
8.30e-35 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 131.34 E-value: 8.30e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLLSKTEGSIHMcgvpienTKEIRnmVGYLPQDFS 85
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDrIGLVGRNGAGKSTLLKILAGELEPDSGEVSI-------PKGLR--IGYLPQEPP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 86 MYPNMTVYKA-MDYLAVLSDIpLRKRRKI--------------------------------IAKLLSKVNLT-NYQNMKV 131
Cdd:COG0488 72 LDDDLTVLDTvLDGDAELRAL-EAELEELeaklaepdedlerlaelqeefealggweaearAEEILSGLGFPeEDLDRPV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 132 KSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANdrIVILSTHivgD---IEATCENVAILDSG 208
Cdd:COG0488 151 SELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKNYPG--TVLVVSH---DryfLDRVATRILELDRG 225
|
....*..
gi 544973757 209 KVI-YNG 214
Cdd:COG0488 226 KLTlYPG 232
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
5-219 |
1.15e-34 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 128.27 E-value: 1.15e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIeNTKEI--RNmVGYLP 81
Cdd:COG3839 4 LELENVSKSYGGVEALKDIDLDIEDGEFlVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDV-TDLPPkdRN-IAMVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPT 161
Cdd:COG3839 82 QSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDEPL 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 162 AGLDPEERIRFRNllcEIAndRI-------VILSTHivgD-IEA-T-CENVAILDSGKVIYNGSTEAL 219
Cdd:COG3839 162 SNLDAKLRVEMRA---EIK--RLhrrlgttTIYVTH---DqVEAmTlADRIAVMNDGRIQQVGTPEEL 221
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
5-236 |
1.83e-34 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 125.20 E-value: 1.83e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEG-SIHMCGVPI--ENTKEIRNMVGY- 79
Cdd:COG1119 4 LELRNVTVRRGGKTILDDISWTVKPGEHwAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGERRggEDVWELRKRIGLv 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 ---LPQDFsmYPNMTVYKAmdylaVLS---------DIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQA 147
Cdd:COG1119 84 spaLQLRF--PRDETVLDV-----VLSgffdsiglyREPTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 148 LIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRI--VILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL---AKL 222
Cdd:COG1119 157 LVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAptLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEVltsENL 236
|
250
....*....|....
gi 544973757 223 AEGKVYSIEVDKKD 236
Cdd:COG1119 237 SEAFGLPVEVERRD 250
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
20-162 |
3.57e-34 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 121.60 E-value: 3.57e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 20 LDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI--ENTKEIRNMVGYLPQDFSMYPNMTVYKAM 96
Cdd:pfam00005 1 LKNVSLTLNPGeILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLtdDERKSLRKEIGYVFQDPQLFPRLTVRENL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 97 DYLAVLSDIPLRKRRKIIAKLLSKVNLTNY----QNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:pfam00005 81 RLGLLLKGLSKREKDARAEEALEKLGLGDLadrpVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
5-209 |
3.75e-34 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 122.11 E-value: 3.75e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFG--KKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGY 79
Cdd:cd03228 1 IEFKNVSFSYPgrPKPVLKDVSLTIKPGEKvAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRdlDLESLRKNIAY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYpNMTVYKamdylavlsdiplrkrrkiiakllskvNLtnyqnmkvksLSGGMNRRLGIAQALIHNPRVLIVDE 159
Cdd:cd03228 81 VPQDPFLF-SGTIRE---------------------------NI----------LSGGQRQRIAIARALLRDPPILILDE 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 544973757 160 PTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEAtCENVAILDSGK 209
Cdd:cd03228 123 ATSALDPETEALILEALRALAKGKTVIVIAHRLSTIRD-ADRIIVLDDGR 171
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
5-217 |
4.42e-34 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 123.99 E-value: 4.42e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQaLDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQD 83
Cdd:cd03299 1 LKVENLSKDWKEFK-LKNVSLEVERGdYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKRDISYVPQN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVYKAMDY-LAVLSDIPLRKRRKI--IAKLLskvNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:cd03299 80 YALFPHMTVYKNIAYgLKKRKVDKKEIERKVleIAEML---GIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEP 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 161 TAGLDPEERIRFRNLLCEI--ANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTE 217
Cdd:cd03299 157 FSALDVRTKEKLREELKKIrkEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPE 215
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
5-228 |
4.55e-34 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 130.72 E-value: 4.55e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFG--KKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGY 79
Cdd:COG2274 474 IELENVSFRYPgdSPPVLDNISLTIKPGERvAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRqiDPASLRRQIGV 553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYP-----NMT----------VYKAMDYLAVLSDI---PLRkrrkiiakllskvnltnYqNMKV----KSLSGG 137
Cdd:COG2274 554 VLQDVFLFSgtireNITlgdpdatdeeIIEAARLAGLHDFIealPMG-----------------Y-DTVVgeggSNLSGG 615
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 138 MNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTH---IVGDieatCENVAILDSGKVIYNG 214
Cdd:COG2274 616 QRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLKGRTVIIIAHrlsTIRL----ADRIIVLDKGRIVEDG 691
|
250
....*....|....
gi 544973757 215 STEALakLAEGKVY 228
Cdd:COG2274 692 THEEL--LARKGLY 703
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-219 |
5.16e-34 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 129.25 E-value: 5.16e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRF--GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKT---EGSIHMCGVPIENTKE-- 72
Cdd:COG1123 1 MTPLLEVRDLSVRYpgGDVPAVDGVSLTIAPGETvALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEal 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 73 IRNMVGYLPQDFSMYPNM-TVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHN 151
Cdd:COG1123 81 RGRRIGMVFQDPMTQLNPvTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALD 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 152 PRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:COG1123 161 PDLLIADEPTTALDVTTQAEILDLLRELQRERgtTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEI 230
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-224 |
7.27e-34 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 128.61 E-value: 7.27e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCG--VPIENTKE-IRNM 76
Cdd:COG3845 2 MPPALELRGITKRFGGVVANDDVSLTVRPGeIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGkpVRIRSPRDaIALG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 VGYLPQDFSMYPNMTVYK----AMDYLAVLSdIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNP 152
Cdd:COG3845 82 IGMVHQHFMLVPNLTVAEnivlGLEPTKGGR-LDRKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGA 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 153 RVLIVDEPTAGLDPEERIRF----RNLlceIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL--AKLAE 224
Cdd:COG3845 161 RILILDEPTAVLTPQEADELfeilRRL---AAEGKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDTAETseEELAE 235
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
16-214 |
2.33e-33 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 121.61 E-value: 2.33e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 16 KKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLL---SKTEGSIHMCGVPIeNTKEIRNMVGYLPQDFSMYPNMT 91
Cdd:cd03234 19 YARILNDVSLHVESGqVMAILGSSGSGKTTLLDAISGRVeggGTTSGQILFNGQPR-KPDQFQKCVAYVRQDDILLPGLT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 92 VYKAMDYLAVLSdIPLRKRRKIIAK-----LLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDP 166
Cdd:cd03234 98 VRETLTYTAILR-LPRKSSDAIRKKrvedvLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDS 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 544973757 167 EERIRFRNLLCEIA-NDRIVILSTHIVG-DIEATCENVAILDSGKVIYNG 214
Cdd:cd03234 177 FTALNLVSTLSQLArRNRIVILTIHQPRsDLFRLFDRILLLSSGEIVYSG 226
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
5-219 |
3.47e-33 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 121.64 E-value: 3.47e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGK-KQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI--ENTKEIRNMVGYL 80
Cdd:cd03295 1 IEFENVTKRYGGgKKAVNNLNLEIAKGEFlVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIreQDPVELRRKIGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNL--TNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVD 158
Cdd:cd03295 81 IQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAADPPLLLMD 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 159 EPTAGLDPEERIR----FRNLLCEIAndRIVILSTHivgDI-EATC--ENVAILDSGKVIYNGSTEAL 219
Cdd:cd03295 161 EPFGALDPITRDQlqeeFKRLQQELG--KTIVFVTH---DIdEAFRlaDRIAIMKNGEIVQVGTPDEI 223
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
15-214 |
4.48e-33 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 119.96 E-value: 4.48e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 15 GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLS--KTEGSIHMCGVPIEnTKEIRNMVGYLPQDFSMYPNMT 91
Cdd:cd03213 20 SGKQLLKNVSGKAKPGeLTAIMGPSGAGKSTLLNALAGRRTglGVSGEVLINGRPLD-KRSFRKIIGYVPQDDILHPTLT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 92 VYKAMDYLAVLsdiplrkrrkiiakllskvnltnyqnmkvKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIR 171
Cdd:cd03213 99 VRETLMFAAKL-----------------------------RGLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQ 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 544973757 172 FRNLLCEIAND-RIVILSTHIV-GDIEATCENVAILDSGKVIYNG 214
Cdd:cd03213 150 VMSLLRRLADTgRTIICSIHQPsSEIFELFDKLLLLSQGRVIYFG 194
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
5-167 |
1.43e-32 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 119.17 E-value: 1.43e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK----EIRNMVGY 79
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGeVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKkninELRQKVGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYPNMTVYKAMdylaVLSDIPLRKRRKIIA-----KLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRV 154
Cdd:cd03262 81 VFQQFNLFPHLTVLENI----TLAPIKVKGMSKAEAeeralELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKV 156
|
170
....*....|...
gi 544973757 155 LIVDEPTAGLDPE 167
Cdd:cd03262 157 MLFDEPTSALDPE 169
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
7-220 |
2.22e-32 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 119.08 E-value: 2.22e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENT---KEIRNMVGYLPQ 82
Cdd:cd03224 3 VENLNAGYGKSQILFGVSLTVPEGeIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLpphERARAGIGYVPE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVYKAMdyLAVLSDIPLRKRRKIIAKLLSKV-NLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPT 161
Cdd:cd03224 83 GRRIFPELTVEENL--LLGAYARRRAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPS 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 162 AGLDP--EERIrFRnLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGKVIYNGSTEALA 220
Cdd:cd03224 161 EGLAPkiVEEI-FE-AIRELRDEGVtILLVEQNARFALEIADRAYVLERGRVVLEGTAAELL 220
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
5-213 |
3.22e-32 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 118.88 E-value: 3.22e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQD 83
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFfTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:cd03300 81 YALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544973757 164 LDPEERirfRNLLCEIAN--DRI---VILSTHIVGDIEATCENVAILDSGKV--------IYN 213
Cdd:cd03300 161 LDLKLR---KDMQLELKRlqKELgitFVFVTHDQEEALTMSDRIAVMNKGKIqqigtpeeIYE 220
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
9-214 |
5.78e-32 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 117.78 E-value: 5.78e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 9 NLSKRFGKKQA---LdNINLEIDSGMFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNM------VGY 79
Cdd:cd03297 1 MLCVDIEKRLPdftL-KIDFDLNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKKINLppqqrkIGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYPNMTVYKAMDY-LAVLSDIPLRKRrkiIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVD 158
Cdd:cd03297 80 VFQQYALFPHLNVRENLAFgLKRKRNREDRIS---VDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLD 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 159 EPTAGLDPEERIRFRNLLCEIAND--RIVILSTHIVGDIEATCENVAILDSGKVIYNG 214
Cdd:cd03297 157 EPFSALDRALRLQLLPELKQIKKNlnIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
5-211 |
1.40e-31 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 115.22 E-value: 1.40e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIentkEIRNmvgylpqd 83
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGeVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEV----SFAS-------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 fsmypnmtvykamdylavlsdiPLRKRRKIIAkllskvnlTNYQnmkvksLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:cd03216 69 ----------------------PRDARRAGIA--------MVYQ------LSVGERQMVEIARALARNARLLILDEPTAA 112
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 544973757 164 LDPEERIRFRNLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGKVI 211
Cdd:cd03216 113 LTPAEVERLFKVIRRLRAQGVaVIFISHRLDEVFEIADRVTVLRDGRVV 161
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
5-167 |
1.40e-31 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 117.40 E-value: 1.40e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK----EIRNMVGY 79
Cdd:COG1126 2 IEIENLHKSFGDLEVLKGISLDVEKGeVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKkdinKLRRKVGM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYPNMTVykaMDYLAvLSDIPLRKRRKIIAK-----LLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRV 154
Cdd:COG1126 82 VFQQFNLFPHLTV---LENVT-LAPIKVKKMSKAEAEerameLLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKV 157
|
170
....*....|...
gi 544973757 155 LIVDEPTAGLDPE 167
Cdd:COG1126 158 MLFDEPTSALDPE 170
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
5-210 |
1.51e-31 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 116.74 E-value: 1.51e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKK-QALDNINLEIDSGMFG-LLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE-----IRNMV 77
Cdd:cd03292 1 IEFINVTKTYPNGtAALDGINISISAGEFVfLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGraipyLRRKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIV 157
Cdd:cd03292 81 GVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIA 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 544973757 158 DEPTAGLDPEERIRFRNLLCEIaNDR--IVILSTHIVGDIEATCENVAILDSGKV 210
Cdd:cd03292 161 DEPTGNLDPDTTWEIMNLLKKI-NKAgtTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
3-196 |
3.46e-31 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 119.03 E-value: 3.46e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLP 81
Cdd:PRK10851 1 MSIEIANIKKSFGRTQVLNDISLDIPSGqMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QDFSMYPNMTVYkamDYLAV-LSDIPLRKR------RKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRV 154
Cdd:PRK10851 81 QHYALFRHMTVF---DNIAFgLTVLPRRERpnaaaiKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQI 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544973757 155 LIVDEPTAGLDPEERIRFRNLL---------------------CEIAnDRIVILSThivGDIE 196
Cdd:PRK10851 158 LLLDEPFGALDAQVRKELRRWLrqlheelkftsvfvthdqeeaMEVA-DRVVVMSQ---GNIE 216
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-196 |
3.25e-30 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 114.19 E-value: 3.25e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMkIAVSNLSKRFGK----KQALDNINLEIDSGMFG-LLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRN 75
Cdd:COG4525 1 MSM-LTVRHVSVRYPGggqpQPALQDVSLTIESGEFVvALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGADRG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 76 MVGylpQDFSMYPNMTVykaMDYLAV---LSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNP 152
Cdd:COG4525 80 VVF---QKDALLPWLNV---LDNVAFglrLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADP 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 544973757 153 RVLIVDEPTAGLDPEERIRFRNLLCEIAND--RIVILSTHivgDIE 196
Cdd:COG4525 154 RFLLMDEPFGALDALTREQMQELLLDVWQRtgKGVFLITH---SVE 196
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
3-220 |
5.29e-30 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 113.18 E-value: 5.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCG--------VPIENTKEI 73
Cdd:COG4161 1 MSIQLKNINCFYGSHQALFDINLECPSGeTLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGhqfdfsqkPSEKAIRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 74 RNMVGYLPQDFSMYPNMTVykaMDYLA-----VLsDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQAL 148
Cdd:COG4161 81 RQKVGMVFQQYNLWPHLTV---MENLIeapckVL-GLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARAL 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544973757 149 IHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIV-ILSTHIVGDIEATCENVAILDSGKVIYNGSTEALA 220
Cdd:COG4161 157 MMEPQVLLFDEPTAALDPEITAQVVEIIRELSQTGITqVIVTHEVEFARKVASQVVYMEKGRIIEQGDASHFT 229
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
3-224 |
5.77e-30 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 114.37 E-value: 5.77e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGK-----KQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE----NTKE 72
Cdd:PRK13637 1 MSIKIENLTHIYMEgtpfeKKALDNVNIEIEDGEFvGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITdkkvKLSD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 73 IRNMVGYLPQdfsmYPNM-----TVYKAMDYLAV---LSDIPLRKRRKiiaKLLSKVNLtNYQNMKVKS---LSGGMNRR 141
Cdd:PRK13637 81 IRKKVGLVFQ----YPEYqlfeeTIEKDIAFGPInlgLSEEEIENRVK---RAMNIVGL-DYEDYKDKSpfeLSGGQKRR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 142 LGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEI--ANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK13637 153 VAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKELhkEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREV 232
|
....*
gi 544973757 220 AKLAE 224
Cdd:PRK13637 233 FKEVE 237
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
5-221 |
8.92e-30 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 117.94 E-value: 8.92e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF--GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGY 79
Cdd:COG4987 334 LELEDVSFRYpgAGRPVLDGLSLTLPPGeRVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRdlDEDDLRRRIAV 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQD---FsmypNMTVykaMDYLAV----LSDIPLRKrrkiiakLLSKVNLTNYqnmkVKS---------------LSGG 137
Cdd:COG4987 414 VPQRphlF----DTTL---RENLRLarpdATDEELWA-------ALERVGLGDW----LAAlpdgldtwlgeggrrLSGG 475
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 138 MNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEAtCENVAILDSGKVIYNGSTE 217
Cdd:COG4987 476 ERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAGRTVLLITHRLAGLER-MDRILVLEDGRIVEQGTHE 554
|
....
gi 544973757 218 ALAK 221
Cdd:COG4987 555 ELLA 558
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
7-211 |
1.19e-29 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 111.19 E-value: 1.19e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQ-ALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENtKEIRNMVGYLPQD- 83
Cdd:cd03226 2 IENISFSYKKGTeILDDLSLDLYAGeIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKA-KERRKSIGYVMQDv 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 -FSMYPNmTVYKAMDylavLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:cd03226 81 dYQLFTD-SVREELL----LGLKELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTS 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 544973757 163 GLDPEERIRFRNLLCEIAN-DRIVILSTHivgDIE---ATCENVAILDSGKVI 211
Cdd:cd03226 156 GLDYKNMERVGELIRELAAqGKAVIVITH---DYEflaKVCDRVLLLANGAIV 205
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
5-210 |
2.51e-29 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 110.81 E-value: 2.51e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQD 83
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFvVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDRDIAMVFQN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVYKAMDYLAVLSDIP---LRKRRKIIAKLLSkvnLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:cd03301 81 YALYPHMTVYDNIAFGLKLRKVPkdeIDERVREVAELLQ---IEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEP 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 544973757 161 TAGLDPEERIRFRNLLCEI--ANDRIVILSTHIVGDIEATCENVAILDSGKV 210
Cdd:cd03301 158 LSNLDAKLRVQMRAELKRLqqRLGTTTIYVTHDQVEAMTMADRIAVMNDGQI 209
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1-219 |
3.55e-29 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 111.64 E-value: 3.55e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLS--KTEGS-IHMCGVPIE-------N 69
Cdd:PRK09984 1 MQTIIRVEKLAKTFNQHQALHAVDLNIHHGeMVALLGPSGSGKSTLLRHLSGLITgdKSAGShIELLGRTVQregrlarD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 70 TKEIRNMVGYLPQDFSMYPNMTVYKAMdYLAVLSDIPL---------RKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNR 140
Cdd:PRK09984 81 IRKSRANTGYIFQQFNLVNRLSVLENV-LIGALGSTPFwrtcfswftREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 141 RLGIAQALIHNPRVLIVDEPTAGLDPEE-RIRFRNLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGKVIYNGSTEA 218
Cdd:PRK09984 160 RVAIARALMQQAKVILADEPIASLDPESaRIVMDTLRDINQNDGItVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQ 239
|
.
gi 544973757 219 L 219
Cdd:PRK09984 240 F 240
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
9-228 |
3.78e-29 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 111.14 E-value: 3.78e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 9 NLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSI-----HMCGVPIEntKEIRNMVGYLPQ 82
Cdd:PRK10895 8 NLAKAYKGRRVVEDVSLTVNSGeIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIiiddeDISLLPLH--ARARRGIGYLPQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVY-KAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPT 161
Cdd:PRK10895 86 EASIFRRLSVYdNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPF 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 162 AGLDPEERIRFRNLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGKVIYNGS-TEALAKLAEGKVY 228
Cdd:PRK10895 166 AGVDPISVIDIKRIIEHLRDSGLgVLITDHNVRETLAVCERAYIVSQGHLIAHGTpTEILQDEHVKRVY 234
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
10-222 |
5.34e-29 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 115.91 E-value: 5.34e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 10 LSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSK---TEGSIHMCGVPIeNTKEIRNMVGYLPQDFS 85
Cdd:TIGR00955 31 FCRERPRKHLLKNVSGVAKPGeLLAVMGSSGAGKTTLMNALAFRSPKgvkGSGSVLLNGMPI-DAKEMRAISAYVQQDDL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 86 MYPNMTVYKAMDYLAVL---SDIPLRKRRKIIAKLLSKVNLTNYQNMK------VKSLSGGMNRRLGIAQALIHNPRVLI 156
Cdd:TIGR00955 110 FIPTLTVREHLMFQAHLrmpRRVTKKEKRERVDEVLQALGLRKCANTRigvpgrVKGLSGGERKRLAFASELLTDPPLLF 189
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 157 VDEPTAGLDPEERIRFRNLLCEIAND-RIVILSTH-IVGDIEATCENVAILDSGKVIYNGSTEALAKL 222
Cdd:TIGR00955 190 CDEPTSGLDSFMAYSVVQVLKGLAQKgKTIICTIHqPSSELFELFDKIILMAEGRVAYLGSPDQAVPF 257
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
5-243 |
9.41e-29 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 115.88 E-value: 9.41e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGK--KQALDNINLEI-DSGMFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE-NTKEIRNMVGYL 80
Cdd:TIGR01257 929 VCVKNLVKIFEPsgRPAVDRLNITFyENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIEtNLDAVRQSLGMC 1008
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:TIGR01257 1009 PQHNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEP 1088
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 161 TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKvIYNGSTEALAKLAEGKVYSIEVDKKdIENI 240
Cdd:TIGR01257 1089 TSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGR-LYCSGTPLFLKNCFGTGFYLTLVRK-MKNI 1166
|
...
gi 544973757 241 KSR 243
Cdd:TIGR01257 1167 QSQ 1169
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
3-218 |
1.18e-28 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 109.72 E-value: 1.18e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE-----NTKEIRNM 76
Cdd:PRK11124 1 MSIQLNGINCFYGAHQALFDITLDCPQGeTLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDfsktpSDKAIREL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 ---VGYLPQDFSMYPNMTVykaMDYL-------AVLSDIPLRKRRKiiaKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQ 146
Cdd:PRK11124 81 rrnVGMVFQQYNLWPHLTV---QQNLieapcrvLGLSKDQALARAE---KLLERLRLKPYADRFPLHLSGGQQQRVAIAR 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 544973757 147 ALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRI--VILsTHIVGDIEATCENVAILDSGKVIYNGSTEA 218
Cdd:PRK11124 155 ALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGItqVIV-THEVEVARKTASRVVYMENGHIVEQGDASC 227
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
7-219 |
1.49e-28 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 111.30 E-value: 1.49e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRF----GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSK---TEGSIHMCGVPI-----ENTKEI 73
Cdd:COG0444 4 VRNLKVYFptrrGVVKAVDGVSFDVRRGeTLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLlklseKELRKI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 74 R-NMVGYLPQDF--SMYPNMTVYKAM-DYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMkVKS----LSGGMNRRLGIA 145
Cdd:COG0444 84 RgREIQMIFQDPmtSLNPVMTVGDQIaEPLRIHGGLSKAEARERAIELLERVGLPDPERR-LDRypheLSGGMRQRVMIA 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 146 QALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRI--VILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:COG0444 163 RALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGlaILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEEL 238
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
5-219 |
1.54e-28 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 109.41 E-value: 1.54e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGV----PIENTKEIRNMVGY 79
Cdd:PRK09493 2 IEFKNVSKHFGPTQVLHNIDLNIDQGeVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLkvndPKVDERLIRQEAGM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYPNMTvykAMDYLAVLsdiPLRKR-------RKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNP 152
Cdd:PRK09493 82 VFQQFYLFPHLT---ALENVMFG---PLRVRgaskeeaEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKP 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 153 RVLIVDEPTAGLDPEERIRFRNLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK09493 156 KLMLFDEPTSALDPELRHEVLKVMQDLAEEGMtMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVL 223
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
5-215 |
1.68e-28 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 109.83 E-value: 1.68e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF--GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI---ENTKEIRNMVG 78
Cdd:TIGR04520 1 IEVENVSFSYpeSEKPALKNVSLSIEKGEFvAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTldeENLWEIRKKVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 79 YLPQD---------------FSMyPNMTVykamdylavlsdiPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLG 143
Cdd:TIGR04520 81 MVFQNpdnqfvgatveddvaFGL-ENLGV-------------PREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVA 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 144 IAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHivgDIE--ATCENVAILDSGKVIYNGS 215
Cdd:TIGR04520 147 IAGVLAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEgiTVISITH---DMEeaVLADRVIVMNKGKIVAEGT 219
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1-211 |
1.80e-28 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 113.57 E-value: 1.80e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNM- 76
Cdd:COG1129 1 AEPLLEMRGISKSFGGVKALDGVSLELRPGeVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRfrSPRDAQAAg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 VGYLPQDFSMYPNMTVY------------KAMDYlavlsdiplRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGI 144
Cdd:COG1129 81 IAIIHQELNLVPNLSVAeniflgreprrgGLIDW---------RAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEI 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 145 AQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGKVI 211
Cdd:COG1129 152 ARALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQGVaIIYISHRLDEVFEIADRVTVLRDGRLV 219
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
7-196 |
2.19e-28 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 109.40 E-value: 2.19e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGylpQDFS 85
Cdd:PRK11248 4 ISHLYADYGGKPALEDINLTLESGeLLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAERGVVF---QNEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 86 MYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLD 165
Cdd:PRK11248 81 LLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD 160
|
170 180 190
....*....|....*....|....*....|...
gi 544973757 166 PEERIRFRNLLCEIAND--RIVILSTHivgDIE 196
Cdd:PRK11248 161 AFTREQMQTLLLKLWQEtgKQVLLITH---DIE 190
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
3-219 |
3.85e-28 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 111.86 E-value: 3.85e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENT--KEIRNMVGY 79
Cdd:PRK09536 2 PMIDVSDLSVEFGDTTVLDGVDLSVREGSLvGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALsaRAASRRVAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYPNMTVYKAMDylavLSDIPLRKR--------RKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHN 151
Cdd:PRK09536 82 VPQDTSLSFEFDVRQVVE----MGRTPHRSRfdtwtetdRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQA 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 152 PRVLIVDEPTAGLDPEERIRFRNLLCEIAND-RIVILSTHivgDIEAT---CENVAILDSGKVIYNGSTEAL 219
Cdd:PRK09536 158 TPVLLLDEPTASLDINHQVRTLELVRRLVDDgKTAVAAIH---DLDLAaryCDELVLLADGRVRAAGPPADV 226
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
9-219 |
8.90e-28 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 109.81 E-value: 8.90e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 9 NLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTkEIRN----MVGylpQD 83
Cdd:PRK11432 11 NITKRFGSNTVIDNLNLTIKQGtMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHR-SIQQrdicMVF---QS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:PRK11432 87 YALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSN 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 164 LDPEERIRFRNLLCEIaNDRIVILS---THIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK11432 167 LDANLRRSMREKIREL-QQQFNITSlyvTHDQSEAFAVSDTVIVMNKGKIMQIGSPQEL 224
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-219 |
3.27e-27 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 105.99 E-value: 3.27e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMkIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK-------- 71
Cdd:PRK11264 1 MSA-IEVKNLVKKFHGQTVLHGIDLEVKPGeVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIDTARslsqqkgl 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 72 --EIRNMVGYLPQDFSMYPNMTVYK-AMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQAL 148
Cdd:PRK11264 80 irQLRQHVGFVFQNFNLFPHRTVLEnIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARAL 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 149 IHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAND-RIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK11264 160 AMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEkRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKAL 231
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1-220 |
4.38e-27 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 105.45 E-value: 4.38e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMkIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK--EI-RNM 76
Cdd:COG0410 1 MPM-LEVENLHAGYGGIHVLHGVSLEVEEGeIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPphRIaRLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 VGYLPQDFSMYPNMTV--------YKAMDYLAVLSDIP--------LRKRRKIIAkllskvnltnyqnmkvKSLSGG--- 137
Cdd:COG0410 80 IGYVPEGRRIFPSLTVeenlllgaYARRDRAEVRADLErvyelfprLKERRRQRA----------------GTLSGGeqq 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 138 MnrrLGIAQALIHNPRVLIVDEPTAGLDP------EERIRfrnllcEIANDRIVIL----STHIVGDIeatCENVAILDS 207
Cdd:COG0410 144 M---LAIGRALMSRPKLLLLDEPSLGLAPliveeiFEIIR------RLNREGVTILlveqNARFALEI---ADRAYVLER 211
|
250
....*....|...
gi 544973757 208 GKVIYNGSTEALA 220
Cdd:COG0410 212 GRIVLEGTAAELL 224
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
5-219 |
4.81e-27 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 110.60 E-value: 4.81e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEiRNMVG----Y 79
Cdd:NF033858 2 ARLEGVSHRYGKTVALDDVSLDIPAGcMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARH-RRAVCpriaY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDF--SMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIV 157
Cdd:NF033858 81 MPQGLgkNLYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLIL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 158 DEPTAGLDPEERIRFRNLLCEIANDR---IVILSThivGDIE--ATCENVAILDSGKVIYNGSTEAL 219
Cdd:NF033858 161 DEPTTGVDPLSRRQFWELIDRIRAERpgmSVLVAT---AYMEeaERFDWLVAMDAGRVLATGTPAEL 224
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
4-228 |
6.05e-27 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 105.38 E-value: 6.05e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 4 KIAVSNLSKRFGKKQALDNINLEI-DSGMFGLLGRNGAGKTTFMRILATLL-----SKTEGSIHMCGVPI--ENTKEIRN 75
Cdd:PRK14247 3 KIEIRDLKVSFGQVEVLDGVNLEIpDNTITALMGPSGSGKSTLLRVFNRLIelypeARVSGEVYLDGQDIfkMDVIELRR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 76 MVGYLPQDFSMYPNMTVYKAMDYLAVLSDIpLRKRRKIIAKL---LSKVNL----TNYQNMKVKSLSGGMNRRLGIAQAL 148
Cdd:PRK14247 83 RVQMVFQIPNPIPNLSIFENVALGLKLNRL-VKSKKELQERVrwaLEKAQLwdevKDRLDAPAGKLSGGQQQRLCIARAL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 149 IHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGST---------EAL 219
Cdd:PRK14247 162 AFQPEVLLADEPTANLDPENTAKIESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTrevftnprhELT 241
|
....*....
gi 544973757 220 AKLAEGKVY 228
Cdd:PRK14247 242 EKYVTGRLY 250
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
15-192 |
8.82e-27 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 103.27 E-value: 8.82e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 15 GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK----EIRNMVGYLPQDfsmyPN 89
Cdd:TIGR01166 3 GGPEVLKGLNFAAERGeVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPLDYSRkgllERRQRVGLVFQD----PD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 90 MTVYKAmdylAVLSDIPLRKR---------RKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:TIGR01166 79 DQLFAA----DVDQDVAFGPLnlglseaevERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEP 154
|
170 180 190
....*....|....*....|....*....|...
gi 544973757 161 TAGLDPEERIRFRNLLCEI-ANDRIVILSTHIV 192
Cdd:TIGR01166 155 TAGLDPAGREQMLAILRRLrAEGMTVVISTHDV 187
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
3-216 |
9.20e-27 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 106.32 E-value: 9.20e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKK-----QALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGV----------- 65
Cdd:PRK13651 1 MQIKVKNIVKIFNKKlptelKALDNVSVEINQGEFiAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKdeknkkktkek 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 66 ---------------PIENTKEIRNMVGYLPQdFSMYP--NMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNL-TNYQ 127
Cdd:PRK13651 81 ekvleklviqktrfkKIKKIKEIRRRVGVVFQ-FAEYQlfEQTIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLdESYL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 128 NMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEI-ANDRIVILSTHIVGDIEATCENVAILD 206
Cdd:PRK13651 160 QRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLnKQGKTIILVTHDLDNVLEWTKRTIFFK 239
|
250
....*....|
gi 544973757 207 SGKVIYNGST 216
Cdd:PRK13651 240 DGKIIKDGDT 249
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
20-208 |
2.23e-26 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 103.31 E-value: 2.23e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 20 LDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRnMVGYlpQDFSMYPNMTVYKAMdY 98
Cdd:TIGR01184 1 LKGVNLTIQQGEFiSLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDR-MVVF--QNYSLLPWLTVRENI-A 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 99 LAV---LSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNL 175
Cdd:TIGR01184 77 LAVdrvLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEE 156
|
170 180 190
....*....|....*....|....*....|....*
gi 544973757 176 LCEIANDR--IVILSTHIVGDIEATCENVAILDSG 208
Cdd:TIGR01184 157 LMQIWEEHrvTVLMVTHDVDEALLLSDRVVMLTNG 191
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
5-214 |
2.25e-26 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 103.00 E-value: 2.25e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF----------------------GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIH 61
Cdd:cd03220 1 IELENVSKSYptykggssslkklgilgrkgevGEFWALKDVSFEVPRGeRIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 62 MCG--VPIentkeIRNMVGylpqdfsMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMN 139
Cdd:cd03220 81 VRGrvSSL-----LGLGGG-------FNPELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMK 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 140 RRLGIAQALIHNPRVLIVDEPTAGLDPEERIR-FRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNG 214
Cdd:cd03220 149 ARLAFAIATALEPDILLIDEVLAVGDAAFQEKcQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
6-238 |
3.12e-26 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 103.27 E-value: 3.12e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 6 AVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE--IRNM-VGYLP 81
Cdd:COG4674 12 YVEDLTVSFDGFKALNDLSLYVDPGeLRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLTGLDEheIARLgIGRKF 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QDFSMYPNMTVYKAMDyLAVLSDIP----LRKRRK-----IIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNP 152
Cdd:COG4674 92 QKPTVFEELTVFENLE-LALKGDRGvfasLFARLTaeerdRIEEVLETIGLTDKADRLAGLLSHGQKQWLEIGMLLAQDP 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 153 RVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKViyngstealakLAEGKVYSIEV 232
Cdd:COG4674 171 KLLLLDEPVAGMTDAETERTAELLKSLAGKHSVVVVEHDMEFVRQIARKVTVLHQGSV-----------LAEGSLDEVQA 239
|
....*.
gi 544973757 233 DKKDIE 238
Cdd:COG4674 240 DPRVIE 245
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
10-219 |
3.72e-26 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 103.88 E-value: 3.72e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 10 LSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNM----VGYLPQ 82
Cdd:cd03294 30 ILKKTGQTVGVNDVSLDVREGeIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAamSRKELRELrrkkISMVFQ 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:cd03294 110 SFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFS 189
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 163 GLDPEERIRFRNLLCEIAND--RIVILSTHivgD-IEAT--CENVAILDSGKVIYNGSTEAL 219
Cdd:cd03294 190 ALDPLIRREMQDELLRLQAElqKTIVFITH---DlDEALrlGDRIAIMKDGRLVQVGTPEEI 248
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
5-219 |
7.90e-26 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 106.38 E-value: 7.90e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF-GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN--TKEIRNMVGYL 80
Cdd:COG4988 337 IELEDVSFSYpGGRPALDGLSLTIPPGeRVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDldPASWRRQIAWV 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDfsmyP---------NMTVYKAmdylavlsDIPlrkrRKIIAKLLSKVNLTNYqnmkVKS---------------LSG 136
Cdd:COG4988 417 PQN----PylfagtireNLRLGRP--------DAS----DEELEAALEAAGLDEF----VAAlpdgldtplgeggrgLSG 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 137 GMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEAtCENVAILDSGKVIYNGST 216
Cdd:COG4988 477 GQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKGRTVILITHRLALLAQ-ADRILVLDDGRIVEQGTH 555
|
...
gi 544973757 217 EAL 219
Cdd:COG4988 556 EEL 558
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
7-280 |
2.20e-25 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 103.76 E-value: 2.20e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFS 85
Cdd:PRK11607 22 IRNLTKSFDGQHAVDDVSLTIYKGeIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRPINMMFQSYA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 86 MYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLD 165
Cdd:PRK11607 102 LFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALD 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 166 PEERIRFRNLLCEIAnDRI---VILSTHIVGDIEATCENVAILDSGKVIYNGSTEalaklaegKVYSIEVDKKDIENIKS 242
Cdd:PRK11607 182 KKLRDRMQLEVVDIL-ERVgvtCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPE--------EIYEHPTTRYSAEFIGS 252
|
250 260 270
....*....|....*....|....*....|....*...
gi 544973757 243 RFIVIGMLTHGGKATLRIISDDKPFETAVDCNPTIEDG 280
Cdd:PRK11607 253 VNVFEGVLKERQEDGLVIDSPGLVHPLKVDADASVVDN 290
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
16-214 |
2.27e-25 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 100.36 E-value: 2.27e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 16 KKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGYLPQD---F--SMY 87
Cdd:cd03245 16 EIPALDNVSLTIRAGeKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRqlDPADLRRNIGYVPQDvtlFygTLR 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 88 PNMTvykamdylavLSDIPLRKRRKIIAKLLSKVN-LTNYQ----NMKV----KSLSGGMNRRLGIAQALIHNPRVLIVD 158
Cdd:cd03245 96 DNIT----------LGAPLADDERILRAAELAGVTdFVNKHpnglDLQIgergRGLSGGQRQAVALARALLNDPPILLLD 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 159 EPTAGLD--PEERI--RFRNLLCeianDRIVILSTHIVGdIEATCENVAILDSGKVIYNG 214
Cdd:cd03245 166 EPTSAMDmnSEERLkeRLRQLLG----DKTLIIITHRPS-LLDLVDRIIVMDSGRIVADG 220
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
3-232 |
2.29e-25 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 101.39 E-value: 2.29e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK--EIRNMVGY 79
Cdd:PRK13548 1 AMLEARNLSVRLGGRTLLDDVSLTLRPGeVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSpaELARRRAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSM-YPnMTVYK--AMDyLAVLSDIPLRKRRkIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALI------H 150
Cdd:PRK13548 81 LPQHSSLsFP-FTVEEvvAMG-RAPHGLSRAEDDA-LVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 151 NPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR----IVILstHivgDIEAT---CENVAILDSGKVIYNGS-TEALAKL 222
Cdd:PRK13548 158 PPRWLLLDEPTSALDLAHQHHVLRLARQLAHERglavIVVL--H---DLNLAaryADRIVLLHQGRLVADGTpAEVLTPE 232
|
250
....*....|
gi 544973757 223 AEGKVYSIEV 232
Cdd:PRK13548 233 TLRRVYGADV 242
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
5-165 |
3.11e-25 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 103.10 E-value: 3.11e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQD 83
Cdd:PRK09452 15 VELRGISKSFDGKEVISNLDLTINNGEFlTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENRHVNTVFQS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:PRK09452 95 YALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSA 174
|
..
gi 544973757 164 LD 165
Cdd:PRK09452 175 LD 176
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
3-191 |
3.77e-25 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 99.56 E-value: 3.77e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVgYL- 80
Cdd:PRK13539 1 MMLEGEDLACVRGGRVLFSGLSFTLAAGeALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEACH-YLg 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFsMYPNMTVykaMDYLAVLSDIpLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:PRK13539 80 HRNA-MKPALTV---AENLEFWAAF-LGGEELDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEP 154
|
170 180 190
....*....|....*....|....*....|..
gi 544973757 161 TAGLDPEERIRFRNLLCE-IANDRIVILSTHI 191
Cdd:PRK13539 155 TAALDAAAVALFAELIRAhLAQGGIVIAATHI 186
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
5-217 |
5.71e-25 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 101.80 E-value: 5.71e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF----GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEI---R 74
Cdd:PRK11153 2 IELKNISKVFpqggRTIHALNNVSLHIPAGeIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTalSEKELrkaR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 75 NMVGYLPQDFSMYPNMTVYkamDYLAV---LSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHN 151
Cdd:PRK11153 82 RQIGMIFQHFNLLSSRTVF---DNVALpleLAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASN 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 152 PRVLIVDEPTAGLDPEERIRFRNLLCEIaNDRI---VILSTHIVGDIEATCENVAILDSGKVIYNGSTE 217
Cdd:PRK11153 159 PKVLLCDEATSALDPATTRSILELLKDI-NRELgltIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVS 226
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1-217 |
8.74e-25 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 99.39 E-value: 8.74e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRF----------------------GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTE 57
Cdd:COG1134 1 MSSMIEVENVSKSYrlyhepsrslkelllrrrrtrrEEFWALKDVSFEVERGeSVGIIGRNGAGKSTLLKLIAGILEPTS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 58 GSIHMCG---VPIEntkeirnmVGylpqdFSMYPNMTVYKAMDYLAVLsdipLRKRRKIIAKLLSKV----NLTNYQNMK 130
Cdd:COG1134 81 GRVEVNGrvsALLE--------LG-----AGFHPELTGRENIYLNGRL----LGLSRKEIDEKFDEIvefaELGDFIDQP 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 131 VKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAND-RIVILSTHIVGDIEATCENVAILDSGK 209
Cdd:COG1134 144 VKTYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRESgRTVIFVSHSMGAVRRLCDRAIWLEKGR 223
|
....*...
gi 544973757 210 VIYNGSTE 217
Cdd:COG1134 224 LVMDGDPE 231
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
5-245 |
1.18e-24 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 99.68 E-value: 1.18e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFG--KKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI--ENTKEIRNMVGY 79
Cdd:PRK13632 8 IKVENVSFSYPnsENNALKNVSFEINEGEYvAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITIskENLKEIRKKIGI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQD-FSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVD 158
Cdd:PRK13632 88 IFQNpDNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 159 EPTAGLDPEERIRFRNLLCEIANDR--IVILSTHivgDI-EAT-CENVAILDSGKVIyngstealaklAEGKVYSIEVDK 234
Cdd:PRK13632 168 ESTSMLDPKGKREIKKIMVDLRKTRkkTLISITH---DMdEAIlADKVIVFSEGKLI-----------AQGKPKEILNNK 233
|
250
....*....|...
gi 544973757 235 KDIENIK--SRFI 245
Cdd:PRK13632 234 EILEKAKidSPFI 246
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
5-167 |
1.31e-24 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 102.84 E-value: 1.31e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLLSKTEGSIHMcGvpiENTKeirnmVGYLPQD 83
Cdd:COG0488 316 LELEGLSKSYGDKTLLDDLSLRIDRGDrIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-G---ETVK-----IGYFDQH 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 F-SMYPNMTVYkamDYLAVLSDiplRKRRKIIAKLLSKVNLT-NYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPT 161
Cdd:COG0488 387 QeELDPDKTVL---DELRDGAP---GGTEQEVRGYLGRFLFSgDDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPT 460
|
....*.
gi 544973757 162 AGLDPE 167
Cdd:COG0488 461 NHLDIE 466
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
16-219 |
2.20e-24 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 99.52 E-value: 2.20e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 16 KKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI------ENTKEIRNMVGYLPQdfsmYP 88
Cdd:PRK13641 19 EKKGLDNISFELEEGSFvALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHItpetgnKNLKKLRKKVSLVFQ----FP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 89 NMTVYKAmdylAVLSDI---PL------RKRRKIIAKLLSKVNLTnyQNMKVKS---LSGGMNRRLGIAQALIHNPRVLI 156
Cdd:PRK13641 95 EAQLFEN----TVLKDVefgPKnfgfseDEAKEKALKWLKKVGLS--EDLISKSpfeLSGGQMRRVAIAGVMAYEPEILC 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 544973757 157 VDEPTAGLDPEERIRFRNLLCEI-ANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK13641 169 LDEPAAGLDPEGRKEMMQLFKDYqKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEI 232
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
5-210 |
2.38e-24 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 98.60 E-value: 2.38e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE-IRNMVgylpQ 82
Cdd:PRK11247 13 LLLNAVSKRYGERTVLNQLDLHIPAGQFvAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEAREdTRLMF----Q 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVykaMDYLAvlsdIPLR-KRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPT 161
Cdd:PRK11247 89 DARLLPWKKV---IDNVG----LGLKgQWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPL 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 544973757 162 AGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKV 210
Cdd:PRK11247 162 GALDALTRIEMQDLIESLWQQHgfTVLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
5-197 |
2.59e-24 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 97.04 E-value: 2.59e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEI--RNM--VGY 79
Cdd:TIGR01189 1 LAARNLACSRGERMLFEGLSFTLNAGeALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEphENIlyLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPqdfSMYPNMTVYKAMDYLAVLsdipLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDE 159
Cdd:TIGR01189 81 LP---GLKPELSALENLHFWAAI----HGGAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDE 153
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 544973757 160 PTAGLDPEERIRFRNLLCE-IANDRIVILSTHI-VGDIEA 197
Cdd:TIGR01189 154 PTTALDKAGVALLAGLLRAhLARGGIVLLTTHQdLGLVEA 193
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
5-211 |
4.52e-24 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 97.12 E-value: 4.52e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF----GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE-----IR 74
Cdd:COG4181 9 IELRGLTKTVgtgaGELTILKGISLEVEAGESvAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEdararLR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 75 N-MVGYLPQDFSMYPNMTvykAMDYLAVlsdiPL-----RKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQAL 148
Cdd:COG4181 89 ArHVGFVFQSFQLLPTLT---ALENVML----PLelagrRDARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAF 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 544973757 149 IHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEAtCENVAILDSGKVI 211
Cdd:COG4181 162 ATEPAILFADEPTGNLDAATGEQIIDLLFELNRERgtTLVLVTHDPALAAR-CDRVLRLRAGRLV 225
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
2-219 |
8.58e-24 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 97.35 E-value: 8.58e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 2 EMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGvpiENTKEIRNMVGYL 80
Cdd:PRK10619 3 ENKLNVIDLHKRYGEHEVLKGVSLQANAGdVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNG---QTINLVRDKDGQL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 P------------------QDFSMYPNMTVYK-AMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKS-LSGGMNR 140
Cdd:PRK10619 80 KvadknqlrllrtrltmvfQHFNLWSHMTVLEnVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVhLSGGQQQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 141 RLGIAQALIHNPRVLIVDEPTAGLDPE---ERIRFRNLLCEIANDRIVIlsTHIVGDIEATCENVAILDSGKVIYNGSTE 217
Cdd:PRK10619 160 RVSIARALAMEPEVLLFDEPTSALDPElvgEVLRIMQQLAEEGKTMVVV--THEMGFARHVSSHVIFLHQGKIEEEGAPE 237
|
..
gi 544973757 218 AL 219
Cdd:PRK10619 238 QL 239
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
18-221 |
9.31e-24 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 97.61 E-value: 9.31e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 18 QALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK----EIRNMVGYLPQD-----FSMy 87
Cdd:PRK13636 20 HALKGININIKKGeVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDYSRkglmKLRESVGMVFQDpdnqlFSA- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 88 pnmTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE 167
Cdd:PRK13636 99 ---SVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPM 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 168 ERIRFRNLLCEIAN--DRIVILSTHIVGDIEATCENVAILDSGKVIYNGS-TEALAK 221
Cdd:PRK13636 176 GVSEIMKLLVEMQKelGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNpKEVFAE 232
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
1-217 |
1.12e-23 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 96.83 E-value: 1.12e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEI-DSGMFGLLGRNGAGKTTFMRILATLL-----SKTEGSIHMCGVPIENTK--- 71
Cdd:PRK14267 1 MKFAIETVNLRVYYGSNHVIKGVDLKIpQNGVFALMGPSGCGKSTLLRTFNRLLelneeARVEGEVRLFGRNIYSPDvdp 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 72 -EIRNMVGYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRR--KIIAKLLSKVNL----TNYQNMKVKSLSGGMNRRLGI 144
Cdd:PRK14267 81 iEVRREVGMVFQYPNPFPHLTIYDNVAIGVKLNGLVKSKKEldERVEWALKKAALwdevKDRLNDYPSNLSGGQRQRLVI 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544973757 145 AQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTE 217
Cdd:PRK14267 161 ARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTR 233
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
19-232 |
1.14e-23 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 100.86 E-value: 1.14e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 19 ALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEIRNMVGYLPQdFSMYPNMTVYKAM 96
Cdd:TIGR01257 1954 AVDRLCVGVRPGeCFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSIlTNISDVHQNMGYCPQ-FDAIDDLLTGREH 2032
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 97 DYL-AVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNL 175
Cdd:TIGR01257 2033 LYLyARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNT 2112
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 176 LCEIAND-RIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL-AKLAEGKVYSIEV 232
Cdd:TIGR01257 2113 IVSIIREgRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHLkSKFGDGYIVTMKI 2171
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
18-215 |
2.24e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 96.73 E-value: 2.24e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 18 QALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENT------KEIRNMVGYLPQdfsmYPNM 90
Cdd:PRK13643 20 RALFDIDLEVKKGSYtALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTskqkeiKPVRKKVGVVFQ----FPES 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 91 TVYKAmdylAVLSDIPL---------RKRRKIIAKLLSKVNLTN-YQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:PRK13643 96 QLFEE----TVLKDVAFgpqnfgipkEKAEKIAAEKLEMVGLADeFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEP 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 161 TAGLDPEERIRFRNLLCEI-ANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGS 215
Cdd:PRK13643 172 TAGLDPKARIEMMQLFESIhQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGT 227
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
1-219 |
2.84e-23 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 98.18 E-value: 2.84e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFG---------------KKQALD---------NINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSK 55
Cdd:PRK10070 1 MAIKLEIKNLYKIFGehpqrafkyieqglsKEQILEktglslgvkDASLAIEEGeIFVIMGLSGSGKSTMVRLLNRLIEP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 56 TEGSIHMCGVPIENTKEI------RNMVGYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNM 129
Cdd:PRK10070 81 TRGQVLIDGVDIAKISDAelrevrRKKIAMVFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 130 KVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEI--ANDRIVILSTHIVGDIEATCENVAILDS 207
Cdd:PRK10070 161 YPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLqaKHQRTIVFISHDLDEAMRIGDRIAIMQN 240
|
250
....*....|..
gi 544973757 208 GKVIYNGSTEAL 219
Cdd:PRK10070 241 GEVVQVGTPDEI 252
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
5-214 |
2.97e-23 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 93.53 E-value: 2.97e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFG--KKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN-TKEIRNMVGYL 80
Cdd:cd03247 1 LSINNVSFSYPeqEQQVLKNLSLELKQGEkIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDlEKALSSLISVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFSMYpnmtvykamdylavlsdiplrkrrkiiakllskvNLTNYQNMKvKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:cd03247 81 NQRPYLF----------------------------------DTTLRNNLG-RRFSGGERQRLALARILLQDAPIVLLDEP 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 544973757 161 TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATcENVAILDSGKVIYNG 214
Cdd:cd03247 126 TVGLDPITERQLLSLIFEVLKDKTLIWITHHLTGIEHM-DKILFLENGKIIMQG 178
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
5-210 |
3.21e-23 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 93.43 E-value: 3.21e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQA--LDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGY 79
Cdd:cd03246 1 LEVENVSFRYPGAEPpvLRNVSFSIEPGeSLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISqwDPNELGDHVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDfsmypnmtvykamdylavlsdiplrkrrkiiAKLLSKvnlTNYQNMkvksLSGGMNRRLGIAQALIHNPRVLIVDE 159
Cdd:cd03246 81 LPQD-------------------------------DELFSG---SIAENI----LSGGQRQRLGLARALYGNPRILVLDE 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 544973757 160 PTAGLDPE-ERIRFRNLLCEIANDRIVILSTHIVGDIEAtCENVAILDSGKV 210
Cdd:cd03246 123 PNSHLDVEgERALNQAIAALKAAGATRIVIAHRPETLAS-ADRILVLEDGRV 173
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-190 |
4.79e-23 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 95.10 E-value: 4.79e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLL-----SKTEGSIHMCGVPIENTK--- 71
Cdd:COG1117 8 LEPKIEVRNLNVYYGDKQALKDINLDIPENKvTALIGPSGCGKSTLLRCLNRMNdlipgARVEGEILLDGEDIYDPDvdv 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 72 -EIRNMVGYLPQdfsmYPN---MTVYKAMDYLAVLSDIplRKRRK---IIAKLLSKVNLTNyqnmKVK--------SLSG 136
Cdd:COG1117 88 vELRRRVGMVFQ----KPNpfpKSIYDNVAYGLRLHGI--KSKSEldeIVEESLRKAALWD----EVKdrlkksalGLSG 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 544973757 137 GMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTH 190
Cdd:COG1117 158 GQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDYTIVIVTH 211
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
5-166 |
1.57e-22 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 94.00 E-value: 1.57e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGK-----KQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIR--NM 76
Cdd:COG1101 2 LELKNLSKTFNPgtvneKRALDGLNLTIEEGDFvTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKraKY 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 VGYLPQDFSM--YPNMTVYK--AMDY---------LAVLsdiplRKRRKIIAKLLSKVN--LTNYQNMKVKSLSGGMNRR 141
Cdd:COG1101 82 IGRVFQDPMMgtAPSMTIEEnlALAYrrgkrrglrRGLT-----KKRRELFRELLATLGlgLENRLDTKVGLLSGGQRQA 156
|
170 180
....*....|....*....|....*
gi 544973757 142 LGIAQALIHNPRVLIVDEPTAGLDP 166
Cdd:COG1101 157 LSLLMATLTKPKLLLLDEHTAALDP 181
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
34-214 |
1.68e-22 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 92.56 E-value: 1.68e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 34 LLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDyLAVLSDIPLR-KRRK 112
Cdd:cd03298 29 IVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRPVSMLFQENNLFAHLTVEQNVG-LGLSPGLKLTaEDRQ 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 113 IIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTH 190
Cdd:cd03298 108 AIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDLHAETkmTVLMVTH 187
|
170 180
....*....|....*....|....
gi 544973757 191 IVGDIEATCENVAILDSGKVIYNG 214
Cdd:cd03298 188 QPEDAKRLAQRVVFLDNGRIAAQG 211
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
9-220 |
2.66e-22 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 94.79 E-value: 2.66e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 9 NLSKRFGKKQaLDnINLEIDS-GMFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-ENTKEI-----RNMVGYLP 81
Cdd:TIGR02142 4 RFSKRLGDFS-LD-ADFTLPGqGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLfDSRKGIflppeKRRIGYVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKiiAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPT 161
Cdd:TIGR02142 82 QEARLFPHLSVRGNLRYGMKRARPSERRISF--ERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 544973757 162 AGLDPEERIR----FRNLLCEIandRI-VILSTHIVGDIEATCENVAILDSGKVIYNGSTEALA 220
Cdd:TIGR02142 160 AALDDPRKYEilpyLERLHAEF---GIpILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVW 220
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
5-217 |
4.47e-22 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 95.64 E-value: 4.47e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF-----GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGS---------IHMCGVPIEN 69
Cdd:TIGR03269 280 IKVRNVSKRYisvdrGVVKAVDNVSLEVKEGeIFGIVGTSGAGKTTLSKIIAGVLEPTSGEvnvrvgdewVDMTKPGPDG 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 70 TKEIRNMVGYLPQDFSMYPNMTVykaMDYL--AVLSDIP--LRKRRKIIAklLSKVNLTNYQNMKV-----KSLSGGMNR 140
Cdd:TIGR03269 360 RGRAKRYIGILHQEYDLYPHRTV---LDNLteAIGLELPdeLARMKAVIT--LKMVGFDEEKAEEIldkypDELSEGERH 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 141 RLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNllcEIANDRIVILSTHIVGD-----IEATCENVAILDSGKVIYNGS 215
Cdd:TIGR03269 435 RVALAQVLIKEPRIVILDEPTGTMDPITKVDVTH---SILKAREEMEQTFIIVShdmdfVLDVCDRAALMRDGKIVKIGD 511
|
..
gi 544973757 216 TE 217
Cdd:TIGR03269 512 PE 513
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
5-235 |
4.77e-22 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 92.16 E-value: 4.77e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFG--KKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGY 79
Cdd:cd03252 1 ITFEHVRFRYKpdGPVILDNISLRIKPGeVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLAlaDPAWLRRQVGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYpNMTVykaMDYLAVLSDIPLRKRRKIIAKL------LSKVNLtNYQNM---KVKSLSGGMNRRLGIAQALIH 150
Cdd:cd03252 81 VLQENVLF-NRSI---RDNIALADPGMSMERVIEAAKLagahdfISELPE-GYDTIvgeQGAGLSGGQRQRIAIARALIH 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 151 NPRVLIVDEPTAGLDPE-ERIRFRNLLcEIANDRIVILSTHIVGDIEaTCENVAILDSGKVIYNGSTEALakLAEGKVYS 229
Cdd:cd03252 156 NPRILIFDEATSALDYEsEHAIMRNMH-DICAGRTVIIIAHRLSTVK-NADRIIVMEKGRIVEQGSHDEL--LAENGLYA 231
|
....*.
gi 544973757 230 IEVDKK 235
Cdd:cd03252 232 YLYQLQ 237
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
5-190 |
6.06e-22 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 95.05 E-value: 6.06e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF-GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGYL 80
Cdd:TIGR02857 322 LEFSGVSVAYpGRRPALRPVSFTVPPGeRVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLAdaDADSWRDQIAWV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFSMYPNmtvykamdylAVLSDIPLRKR---RKIIAKLLSKVNLTNY-------QNMKVKS----LSGGMNRRLGIAQ 146
Cdd:TIGR02857 402 PQHPFLFAG----------TIAENIRLARPdasDAEIREALERAGLDEFvaalpqgLDTPIGEggagLSGGQAQRLALAR 471
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 544973757 147 ALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTH 190
Cdd:TIGR02857 472 AFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQGRTVLLVTH 515
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
5-215 |
9.84e-22 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 91.99 E-value: 9.84e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEID-SGMFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE----IRNMVGY 79
Cdd:PRK13638 2 LATSDLWFRYQDEPVLKGLNLDFSlSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRgllaLRQQVAT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDfsmyPNMTVYkamdYLAVLSDIPLRKRRKIIAK---------LLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIH 150
Cdd:PRK13638 82 VFQD----PEQQIF----YTDIDSDIAFSLRNLGVPEaeitrrvdeALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 151 NPRVLIVDEPTAGLDPEERIRFRNLLCEI-ANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGS 215
Cdd:PRK13638 154 QARYLLLDEPTAGLDPAGRTQMIAIIRRIvAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGA 219
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
18-215 |
1.30e-21 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 91.68 E-value: 1.30e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 18 QALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK----EIRNMVGYL---PQDFSMYPn 89
Cdd:PRK13639 16 EALKGINFKAEKGeMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKYDKksllEVRKTVGIVfqnPDDQLFAP- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 90 mTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEER 169
Cdd:PRK13639 95 -TVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGA 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 544973757 170 IRFRNLLCEIANDRI-VILSTHIVGDIEATCENVAILDSGKVIYNGS 215
Cdd:PRK13639 174 SQIMKLLYDLNKEGItIIISTHDVDLVPVYADKVYVMSDGKIIKEGT 220
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
5-219 |
1.43e-21 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 91.20 E-value: 1.43e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN--TKEIRNM-VGYL 80
Cdd:PRK11300 6 LSVSGLMMRFGGLLAVNNVNLEVREQeIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGlpGHQIARMgVVRT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFSMYPNMTVYKAM----------DYLAVLSDIPL--RKRRKII---AKLLSKVNLTNYQNMKVKSLSGGMNRRLGIA 145
Cdd:PRK11300 86 FQHVRLFREMTVIENLlvaqhqqlktGLFSGLLKTPAfrRAESEALdraATWLERVGLLEHANRQAGNLAYGQQRRLEIA 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 146 QALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK11300 166 RCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHnvTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEI 241
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
5-219 |
2.84e-21 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 89.81 E-value: 2.84e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKkQALdNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQD 83
Cdd:COG3840 2 LRLDDLTYRYGD-FPL-RFDLTIAAGERvAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAERPVSMLFQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVYKAMdYLAVLSDIPL-RKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:COG3840 80 NNLFPHLTVAQNI-GLGLRPGLKLtAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFS 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 163 GLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:COG3840 159 ALDPALRQEMLDLVDELCRERglTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAAL 217
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
19-215 |
4.10e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 90.19 E-value: 4.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 19 ALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENT------KEIRNMVGYLPQdfsmYPNMT 91
Cdd:PRK13649 22 ALFDVNLTIEDGSYtAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTsknkdiKQIRKKVGLVFQ----FPESQ 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 92 VYKAmdylAVLSDIPL---------RKRRKIIAKLLSKVNLTnyQNMKVKS---LSGGMNRRLGIAQALIHNPRVLIVDE 159
Cdd:PRK13649 98 LFEE----TVLKDVAFgpqnfgvsqEEAEALAREKLALVGIS--ESLFEKNpfeLSGGQMRRVAIAGILAMEPKILVLDE 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 160 PTAGLDPEERIRFRNLLCEIANDRIVI-LSTHIVGDIEATCENVAILDSGKVIYNGS 215
Cdd:PRK13649 172 PTAGLDPKGRKELMTLFKKLHQSGMTIvLVTHLMDDVANYADFVYVLEKGKLVLSGK 228
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
7-197 |
4.84e-21 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 88.69 E-value: 4.84e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLS---KTEGSI-----HMCGVPIENtkeiRNmV 77
Cdd:COG4136 4 LENLTITLGGRPLLAPLSLTVAPGeILTLMGPSGSGKSTLLAAIAGTLSpafSASGEVllngrRLTALPAEQ----RR-I 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GYLPQDFSMYPNMTVYKAMDYlAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIV 157
Cdd:COG4136 79 GILFQDDLLFPHLSVGENLAF-ALPPTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLL 157
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 544973757 158 DEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEA 197
Cdd:COG4136 158 DEPFSKLDAALRAQFREFVFEQIRQRgiPALLVTHDEEDAPA 199
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
1-220 |
5.97e-21 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 89.79 E-value: 5.97e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGK-KQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI--ENTKEIRNM 76
Cdd:PRK13647 1 MDNIIEVEDLHFRYKDgTKALKGLSLSIPEGsKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVnaENEKWVRSK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 VGYLPQD-----FSMypnmTVYKAMDYLAV---LSDIPLRKRrkiIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQAL 148
Cdd:PRK13647 81 VGLVFQDpddqvFSS----TVWDDVAFGPVnmgLDKDEVERR---VEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVL 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544973757 149 IHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAND-RIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEALA 220
Cdd:PRK13647 154 AMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQgKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLLT 226
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
17-215 |
2.31e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 88.22 E-value: 2.31e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 17 KQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVP---IENTKEIRNMVGYLPQDfsmyPNMTV 92
Cdd:PRK13633 23 KLALDDVNLEVKKGEFlVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDtsdEENLWDIRNKAGMVFQN----PDNQI 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 93 YKAMdylaVLSD---------IPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:PRK13633 99 VATI----VEEDvafgpenlgIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAM 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 544973757 164 LDPEERIRFRNLLCEIaNDR---IVILSTHIVgDIEATCENVAILDSGKVIYNGS 215
Cdd:PRK13633 175 LDPSGRREVVNTIKEL-NKKygiTIILITHYM-EEAVEADRIIVMDSGKVVMEGT 227
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
5-209 |
2.65e-20 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 84.81 E-value: 2.65e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIhmcgvpienTKEIRNMVGYLPQd 83
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGdRIGLVGRNGAGKSTLLKLIAGELEPDEGIV---------TWGSTVKIGYFEQ- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 fsmypnmtvykamdylavlsdiplrkrrkiiakllskvnltnyqnmkvksLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:cd03221 71 --------------------------------------------------LSGGEKMRLALAKLLLENPNLLLLDEPTNH 100
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 544973757 164 LDPEERIRFRNLLceIANDRIVILSTHivgD---IEATCENVAILDSGK 209
Cdd:cd03221 101 LDLESIEALEEAL--KEYPGTVILVSH---DryfLDQVATKIIELEDGK 144
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
15-217 |
2.90e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 87.94 E-value: 2.90e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 15 GKKQALDNINLEID-SGMFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI--ENTKEIRNMVGYL---PQDFSMYP 88
Cdd:PRK13652 15 GSKEALNNINFIAPrNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPItkENIREVRKFVGLVfqnPDDQIFSP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 89 NMTVYKAMDYLAVLSDIPLRKRRkiIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE- 167
Cdd:PRK13652 95 TVEQDIAFGPINLGLDEETVAHR--VSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQg 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 544973757 168 --ERIRFRNLLCEIANdRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTE 217
Cdd:PRK13652 173 vkELIDFLNDLPETYG-MTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVE 223
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
15-228 |
4.35e-20 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 89.84 E-value: 4.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 15 GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGYLPQDFSMY---- 87
Cdd:COG1132 351 GDRPVLKDISLTIPPGeTVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRdlTLESLRRQIGVVPQDTFLFsgti 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 88 --------PNMT---VYKAMDyLAVLSDiplrkrrkIIAKLLSKvnltnYQNMkV----KSLSGGMNRRLGIAQALIHNP 152
Cdd:COG1132 431 renirygrPDATdeeVEEAAK-AAQAHE--------FIEALPDG-----YDTV-VgergVNLSGGQRQRIAIARALLKDP 495
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 153 RVLIVDEPTAGLDPE-ERIRFRNLLcEIANDRIVI-----LSThivgdIEAtCENVAILDSGKVIYNGSTEALakLAEGK 226
Cdd:COG1132 496 PILILDEATSALDTEtEALIQEALE-RLMKGRTTIviahrLST-----IRN-ADRILVLDDGRIVEQGTHEEL--LARGG 566
|
..
gi 544973757 227 VY 228
Cdd:COG1132 567 LY 568
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
15-219 |
5.83e-20 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 86.13 E-value: 5.83e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 15 GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGYLPQDFSMYPNmT 91
Cdd:cd03254 14 EKKPVLKDINFSIKPGETvAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRdiSRKSLRSMIGVVLQDTFLFSG-T 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 92 VykaMDYLAVLSDIPLRKRRKIIAKLL--------SKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:cd03254 93 I---MENIRLGRPNATDEEVIEAAKEAgahdfimkLPNGYDTVLGENGGNLSQGERQLLAIARAMLRDPKILILDEATSN 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 164 LDPEERIRFRNLLCEIANDRIVILSTHIVGDIEaTCENVAILDSGKVIYNGSTEAL 219
Cdd:cd03254 170 IDTETEKLIQEALEKLMKGRTSIIIAHRLSTIK-NADKILVLDDGKIIEEGTHDEL 224
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
3-219 |
5.93e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 87.14 E-value: 5.93e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGK-----KQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN-TKE--- 72
Cdd:PRK13646 1 MTIRFDNVSYTYQKgtpyeHQAIHDVNTEFEQGKYyAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHkTKDkyi 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 73 --IRNMVGYLPQdfsmYPNM-----TVYKAMDYLAVLSDIPLRKRRKIIAKLLskVNLTNYQNMKVKS---LSGGMNRRL 142
Cdd:PRK13646 81 rpVRKRIGMVFQ----FPESqlfedTVEREIIFGPKNFKMNLDEVKNYAHRLL--MDLGFSRDVMSQSpfqMSGGQMRKI 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 143 GIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAND--RIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK13646 155 AIVSILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQTDenKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKEL 233
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
19-267 |
7.53e-20 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 86.86 E-value: 7.53e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 19 ALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEiRNMVGYLPQ----DFSmYP----- 88
Cdd:PRK15056 22 ALRDASFTVPGGsIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQ-KNLVAYVPQseevDWS-FPvlved 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 89 --NMTVYKAMDYLAvlsdIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDP 166
Cdd:PRK15056 100 vvMMGRYGHMGWLR----RAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 167 EERIRFRNLLCEIAND-RIVILSTHIVGDIEATCEnVAILDSGKVIYNGSTEALAKlaegkvysievdkkdIENIKSRFi 245
Cdd:PRK15056 176 KTEARIISLLRELRDEgKTMLVSTHNLGSVTEFCD-YTVMVKGTVLASGPTETTFT---------------AENLELAF- 238
|
250 260
....*....|....*....|....*..
gi 544973757 246 vIGMLTH----GGKAtlRIISDD-KPF 267
Cdd:PRK15056 239 -SGVLRHvalnGSEE--SIITDDeRPF 262
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
16-215 |
8.58e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 86.78 E-value: 8.58e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 16 KKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLL---SKTEGSIHMCGVPI--ENTKEIRNMVGYLPQD-FSMYP 88
Cdd:PRK13640 19 KKPALNDISFSIPRGSWtALIGHNGSGKSTISKLINGLLlpdDNPNSKITVDGITLtaKTVWDIREKVGIVFQNpDNQFV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 89 NMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEE 168
Cdd:PRK13640 99 GATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAG 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 544973757 169 RIRFRNLLCEIANDR--IVILSTHivgDIE--ATCENVAILDSGKVIYNGS 215
Cdd:PRK13640 179 KEQILKLIRKLKKKNnlTVISITH---DIDeaNMADQVLVLDDGKLLAQGS 226
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
13-190 |
8.60e-20 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 84.59 E-value: 8.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 13 RFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIH-MCGVPientkeirnmVGYLPQDFSMYPNM 90
Cdd:NF040873 1 GYGGRPVLHGVDLTIPAGsLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRrAGGAR----------VAYVPQRSEVPDSL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 91 --TVYKAMDyLAVLSDIPLRKR-----RKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:NF040873 71 plTVRDLVA-MGRWARRGLWRRltrddRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTG 149
|
170 180
....*....|....*....|....*...
gi 544973757 164 LDPEERIRFRNLLCEIAND-RIVILSTH 190
Cdd:NF040873 150 LDAESRERIIALLAEEHARgATVVVVTH 177
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-165 |
9.23e-20 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 85.94 E-value: 9.23e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIhmcgvpiENTKEIRnmVGY 79
Cdd:PRK09544 1 MTSLVSLENVSVSFGQRRVLSDVSLELKPGkILTLLGPNGAGKSTLVRVVLGLVAPDEGVI-------KRNGKLR--IGY 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYPNM--TVYKAMDylavlsdipLRK--RRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVL 155
Cdd:PRK09544 72 VPQKLYLDTTLplTVNRFLR---------LRPgtKKEDILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLL 142
|
170
....*....|
gi 544973757 156 IVDEPTAGLD 165
Cdd:PRK09544 143 VLDEPTQGVD 152
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
3-219 |
1.06e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 86.61 E-value: 1.06e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKK-----QALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE---- 72
Cdd:PRK13634 1 MDITFQKVEHRYQYKtpferRALYDVNVSIPSGSYvAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKKnkkl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 73 --IRNMVGYLPQdfsmYPNMTVYKAmdylAVLSDI---------PLRKRRKIIAKLLSKVNLTnyQNMKVKS---LSGGM 138
Cdd:PRK13634 81 kpLRKKVGIVFQ----FPEHQLFEE----TVEKDIcfgpmnfgvSEEDAKQKAREMIELVGLP--EELLARSpfeLSGGQ 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 139 NRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNGST 216
Cdd:PRK13634 151 MRRVAIAGVLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKglTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTP 230
|
...
gi 544973757 217 EAL 219
Cdd:PRK13634 231 REI 233
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
3-232 |
1.12e-19 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 85.84 E-value: 1.12e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 3 MKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGY 79
Cdd:PRK11231 1 MTLRTENLTVGYGTKRILNDLSLSLPTGkITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISmlSSRQLARRLAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYPNMTV-----YKAMDYLAV---LSDiplrKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHN 151
Cdd:PRK11231 81 LPQHHLTPEGITVrelvaYGRSPWLSLwgrLSA----EDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 152 PRVLIVDEPTAGLDPEERIRFRNLLCEI-ANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGS-----TEALAKlaeg 225
Cdd:PRK11231 157 TPVVLLDEPTTYLDINHQVELMRLMRELnTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTpeevmTPGLLR---- 232
|
....*..
gi 544973757 226 KVYSIEV 232
Cdd:PRK11231 233 TVFDVEA 239
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
9-230 |
1.30e-19 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 85.81 E-value: 1.30e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 9 NLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN--TKEIRNMVGYLPQDFS 85
Cdd:PRK10253 12 QLTLGYGKYTVAENLTVEIPDGHFtAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHyaSKEVARRIGLLAQNAT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 86 MYPNMTVYKAMDYlAVLSDIPLRKR-RK----IIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:PRK10253 92 TPGDITVQELVAR-GRYPHQPLFTRwRKedeeAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEP 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 544973757 161 TAGLDPEERIRFRNLLCEIANDRIVILSThIVGDIEATCE---NVAILDSGKVIYNGSTEAL--AKLAEgKVYSI 230
Cdd:PRK10253 171 TTWLDISHQIDLLELLSELNREKGYTLAA-VLHDLNQACRyasHLIALREGKIVAQGAPKEIvtAELIE-RIYGL 243
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
5-247 |
1.50e-19 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 88.32 E-value: 1.50e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATL--LSKTEGSI--HM----------------- 62
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGeVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRIiyHValcekcgyverpskvge 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 63 ----CGVPIEN------------TKEIRNMVGYLPQ-DFSMYPNMTVYKamDYLAVLSDI--PLRKRRKIIAKLLSKVNL 123
Cdd:TIGR03269 81 pcpvCGGTLEPeevdfwnlsdklRRRIRKRIAIMLQrTFALYGDDTVLD--NVLEALEEIgyEGKEAVGRAVDLIEMVQL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 124 TNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCE--IANDRIVILSTHIVGDIEATCEN 201
Cdd:TIGR03269 159 SHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEavKASGISMVLTSHWPEVIEDLSDK 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 544973757 202 VAILDSGKVIYNG-STEALAKLAEG-----KVYSIEVdKKDI---ENIKSRFIVI 247
Cdd:TIGR03269 239 AIWLENGEIKEEGtPDEVVAVFMEGvseveKECEVEV-GEPIikvRNVSKRYISV 292
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
15-214 |
1.54e-19 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 84.22 E-value: 1.54e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 15 GKKQALDNINLEIDSGMFG-LLGRNGAGKTTFMRILA--TLLSKTEGSIHMCGVPIenTKEIRNMVGYLPQDFSMYPNMT 91
Cdd:cd03232 18 GKRQLLNNISGYVKPGTLTaLMGESGAGKTTLLDVLAgrKTAGVITGEILINGRPL--DKNFQRSTGYVEQQDVHSPNLT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 92 VYKAMDYLAVLSDIPLRKRrkiiakllskvnltnyqnmkvkslsggmnRRLGIAQALIHNPRVLIVDEPTAGLDPEERIR 171
Cdd:cd03232 96 VREALRFSALLRGLSVEQR-----------------------------KRLTIGVELAAKPSILFLDEPTSGLDSQAAYN 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 544973757 172 FRNLLCEIAND-RIVILSTH-IVGDIEATCENVAILDS-GKVIYNG 214
Cdd:cd03232 147 IVRFLKKLADSgQAILCTIHqPSASIFEKFDRLLLLKRgGKTVYFG 192
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-232 |
1.87e-19 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 88.06 E-value: 1.87e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKiavsNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLL--SKTEGSIHMCGVPIE--NTKEI-R 74
Cdd:PRK13549 6 LEMK----NITKTFGGVKALDNVSLKVRAGeIVSLCGENGAGKSTLMKVLSGVYphGTYEGEIIFEGEELQasNIRDTeR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 75 NMVGYLPQDFSMYPNMTV------------YKAMDYLAVLSDIplrkrrkiiAKLLSKVNLTNYQNMKVKSLSGGMNRRL 142
Cdd:PRK13549 82 AGIAIIHQELALVKELSVleniflgneitpGGIMDYDAMYLRA---------QKLLAQLKLDINPATPVGNLGLGQQQLV 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 143 GIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIV-ILSTHIVGDIEATCENVAILDSGKVIyngSTEALAK 221
Cdd:PRK13549 153 EIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAHGIAcIYISHKLNEVKAISDTICVIRDGRHI---GTRPAAG 229
|
250
....*....|.
gi 544973757 222 LAEGKVYSIEV 232
Cdd:PRK13549 230 MTEDDIITMMV 240
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
17-229 |
1.89e-19 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 84.97 E-value: 1.89e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 17 KQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK--EIRNMVGYLPQDFSMYpNMTVY 93
Cdd:cd03253 14 RPVLKDVSFTIPAGkKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTldSLRRAIGVVPQDTVLF-NDTIG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 94 KAMDYLAV-LSDIPLRKRRKiIAKLLSKV-NLTNYQNMKVKS----LSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE 167
Cdd:cd03253 93 YNIRYGRPdATDEEVIEAAK-AAQIHDKImRFPDGYDTIVGErglkLSGGEKQRVAIARAILKNPPILLLDEATSALDTH 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544973757 168 -ERIRFRNLLcEIANDRIVILSTHIVGDIeATCENVAILDSGKVIYNGSTEALakLAEGKVYS 229
Cdd:cd03253 172 tEREIQAALR-DVSKGRTTIVIAHRLSTI-VNADKIIVLKDGRIVERGTHEEL--LAKGGLYA 230
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
5-191 |
7.34e-19 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 82.54 E-value: 7.34e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEI--RNMVgYLP 81
Cdd:cd03231 1 LEADELTCERDGRALFSGLSFTLAAGeALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSiaRGLL-YLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QDFSMYPNMTVYKAMDYLAVLSDiplrkrRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPT 161
Cdd:cd03231 80 HAPGIKTTLSVLENLRFWHADHS------DEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPT 153
|
170 180 190
....*....|....*....|....*....|.
gi 544973757 162 AGLDPEERIRFRNLLC-EIANDRIVILSTHI 191
Cdd:cd03231 154 TALDKAGVARFAEAMAgHCARGGMVVLTTHQ 184
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
5-219 |
9.59e-19 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 83.99 E-value: 9.59e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDS-GMFGLLGRNGAGKTTFMRILATLLSKTEG-----SIHMCGVPIENTK---EIRN 75
Cdd:PRK14271 22 MAAVNLTLGFAGKTVLDQVSMGFPArAVTSLMGPTGSGKTTFLRTLNRMNDKVSGyrysgDVLLGGRSIFNYRdvlEFRR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 76 MVGYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKS----LSGGMNRRLGIAQALIHN 151
Cdd:PRK14271 102 RVGMLFQRPNPFPMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLWDAVKDRLSDspfrLSGGQQQLLCLARTLAVN 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 152 PRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK14271 182 PEVLLLDEPTSALDPTTTEKIEEFIRSLADRLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQL 249
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
5-210 |
1.03e-18 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 85.08 E-value: 1.03e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGMFGL-LGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQD 83
Cdd:PRK11000 4 VTLRNVTKAYGDVVISKDINLDIHEGEFVVfVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAERGVGMVFQS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVYKAMDY---LAVLSDIPLRKRRKIIAKLLskvNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:PRK11000 84 YALYPHLSVAENMSFglkLAGAKKEEINQRVNQVAEVL---QLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 161 TAGLDPEERIRFRnllCEIAN-----DRIVILSTHivGDIEAT--CENVAILDSGKV 210
Cdd:PRK11000 161 LSNLDAALRVQMR---IEISRlhkrlGRTMIYVTH--DQVEAMtlADKIVVLDAGRV 212
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
7-219 |
1.15e-18 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 83.17 E-value: 1.15e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEI-DSGMFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEI--------RNMV 77
Cdd:PRK14246 13 ISRLYLYINDKAILKDITIKIpNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYFGKDIfqidaiklRKEV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKR-RKIIAKLLSKVNL----TNYQNMKVKSLSGGMNRRLGIAQALIHNP 152
Cdd:PRK14246 93 GMVFQQPNPFPHLSIYDNIAYPLKSHGIKEKREiKKIVEECLRKVGLwkevYDRLNSPASQLSGGQQQRLTIARALALKP 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 153 RVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK14246 173 KVLLMDEPTSMIDIVNSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEI 239
|
|
| nickel_nikD |
TIGR02770 |
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ... |
19-219 |
1.64e-18 |
|
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 82.03 E-value: 1.64e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 19 ALDNINLEIDSG-MFGLLGRNGAGKTT----FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQD--FSMYPNMT 91
Cdd:TIGR02770 1 LVQDLNLSLKRGeVLALVGESGSGKSLtclaILGLLPPGLTQTSGEILLDGRPLLPLSIRGRHIATIMQNprTAFNPLFT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 92 VYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVK---SLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEE 168
Cdd:TIGR02770 81 MGNHAIETLRSLGKLSKQARALILEALEAVGLPDPEEVLKKypfQLSGGMLQRVMIALALLLEPPFLIADEPTTDLDVVN 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 544973757 169 RIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:TIGR02770 161 QARVLKLLRELRQLFgtGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEI 213
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
7-165 |
2.06e-18 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 83.63 E-value: 2.06e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKK-----------QALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-----EN 69
Cdd:COG4608 10 VRDLKKHFPVRgglfgrtvgvvKAVDGVSFDIRRGeTLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDItglsgRE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 70 TKEIRNMVGYLPQD--FSMYPNMTVYKAMDY-LAVLSDIPLRKRRKIIAKLLSKVNL-----TNYQNMkvksLSGGMNRR 141
Cdd:COG4608 90 LRPLRRRMQMVFQDpyASLNPRMTVGDIIAEpLRIHGLASKAERRERVAELLELVGLrpehaDRYPHE----FSGGQRQR 165
|
170 180
....*....|....*....|....
gi 544973757 142 LGIAQALIHNPRVLIVDEPTAGLD 165
Cdd:COG4608 166 IGIARALALNPKLIVCDEPVSALD 189
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-214 |
2.44e-18 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 84.45 E-value: 2.44e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVP---IENTKEIRNM 76
Cdd:PRK09700 2 ATPYISMAGIGKSFGPVHALKSVNLTVYPGeIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINynkLDHKLAAQLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 VGYLPQDFSMYPNMTVYKAMdYLAVLS-----DIPL---RKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQAL 148
Cdd:PRK09700 82 IGIIYQELSVIDELTVLENL-YIGRHLtkkvcGVNIidwREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 149 IHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAND-RIVILSTHIVGDIEATCENVAILDSGKVIYNG 214
Cdd:PRK09700 161 MLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEgTAIVYISHKLAEIRRICDRYTVMKDGSSVCSG 227
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
17-219 |
2.49e-18 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 83.61 E-value: 2.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 17 KQALDNINLEID-----SGMFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNM------VGYLPQDFS 85
Cdd:COG4148 8 RLRRGGFTLDVDftlpgRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDSARGIFLpphrrrIGYVFQEAR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 86 MYPNMTVYKAMDYlaVLSDIPlRKRRKI----------IAKLLSKvnltnyqnmKVKSLSGGMNRRLGIAQALIHNPRVL 155
Cdd:COG4148 88 LFPHLSVRGNLLY--GRKRAP-RAERRIsfdevvellgIGHLLDR---------RPATLSGGERQRVAIGRALLSSPRLL 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 156 IVDEPTAGLDPE---------ERIRfrnllceianDRI---VILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:COG4148 156 LMDEPLAALDLArkaeilpylERLR----------DELdipILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEV 221
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
19-219 |
2.52e-18 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 82.73 E-value: 2.52e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 19 ALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVP---IENTKEIRNMVGYLPQD-FSMYPNMTVY 93
Cdd:PRK13644 17 ALENINLVIKKGEYiGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDtgdFSKLQGIRKLVGIVFQNpETQFVGRTVE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 94 KAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIR-F 172
Cdd:PRK13644 97 EDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAvL 176
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 544973757 173 RNLLCEIANDRIVILSTHIVGDIEATcENVAILDSGKVIYNGSTEAL 219
Cdd:PRK13644 177 ERIKKLHEKGKTIVYITHNLEELHDA-DRIIVMDRGKIVLEGEPENV 222
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
5-219 |
3.25e-18 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 84.49 E-value: 3.25e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF--GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE--IRNMVGY 79
Cdd:PRK11160 339 LTLNNVSFTYpdQPQPVLKGLSLQIKAGEKvALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEaaLRQAISV 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQdfsmypnmTVYkamdylaVLSDiPLRKRRKIIAK---------LLSKVNLTNY-QNMKV---------KSLSGGMNR 140
Cdd:PRK11160 419 VSQ--------RVH-------LFSA-TLRDNLLLAAPnasdealieVLQQVGLEKLlEDDKGlnawlgeggRQLSGGEQR 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 141 RLGIAQALIHNPRVLIVDEPTAGLDPE-ERIRFRNLLcEIANDRIVILSTHIVGDIEATcENVAILDSGKVIYNGSTEAL 219
Cdd:PRK11160 483 RLGIARALLHDAPLLLLDEPTEGLDAEtERQILELLA-EHAQNKTVLMITHRLTGLEQF-DRICVMDNGQIIEQGTHQEL 560
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
15-190 |
3.54e-18 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 84.33 E-value: 3.54e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 15 GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK--EIRNMVGYLPQDfsmypnmt 91
Cdd:TIGR02868 346 GAPPVLDGVSLDLPPGeRVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDqdEVRRRVSVCAQD-------- 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 92 vykamdylAVLSDIPLRKRRKI---------IAKLLSKVNLTNY-------QNMKV----KSLSGGMNRRLGIAQALIHN 151
Cdd:TIGR02868 418 --------AHLFDTTVRENLRLarpdatdeeLWAALERVGLADWlralpdgLDTVLgeggARLSGGERQRLALARALLAD 489
|
170 180 190
....*....|....*....|....*....|....*....
gi 544973757 152 PRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTH 190
Cdd:TIGR02868 490 APILLLDEPTEHLDAETADELLEDLLAALSGRTVVLITH 528
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
19-225 |
3.69e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 82.11 E-value: 3.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 19 ALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI--ENTKEIRNMVGYLPQDfsmyP-NMTVYK 94
Cdd:PRK13648 24 TLKDVSFNIPKGQWtSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAItdDNFEKLRKHIGIVFQN----PdNQFVGS 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 95 AMDYLAVLS----DIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERI 170
Cdd:PRK13648 100 IVKYDVAFGlenhAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQ 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 171 RFRNLLCEI-ANDRIVILSthIVGDIEATCEN--VAILDSGKVIYNGSTEALAKLAEG 225
Cdd:PRK13648 180 NLLDLVRKVkSEHNITIIS--ITHDLSEAMEAdhVIVMNKGTVYKEGTPTEIFDHAEE 235
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
6-219 |
3.82e-18 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 81.76 E-value: 3.82e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 6 AVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGYLPQ 82
Cdd:PRK10575 13 ALRNVSFRVPGRTLLHPLSLTFPAGkVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLEswSSKAFARKVAYLPQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVYKamdyLAVLSDIPL--------RKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRV 154
Cdd:PRK10575 93 QLPAAEGMTVRE----LVAIGRYPWhgalgrfgAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRC 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 155 LIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK10575 169 LLLDEPTSALDIAHQVDVLALVHRLSQERglTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEL 235
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1-178 |
4.65e-18 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 80.94 E-value: 4.65e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRF------GKK-QALDNINLEIDSGMF-GLLGRNGAGKTTFMR-ILATLLSkTEGSIHMC--GVPIEN 69
Cdd:COG4778 1 MTTLLEVENLSKTFtlhlqgGKRlPVLDGVSFSVAAGECvALTGPSGAGKSTLLKcIYGNYLP-DSGSILVRhdGGWVDL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 70 TK----EI----RNMVGYLPQDFSMYPNMTvykAMDYLAVlsdiPLRKR-------RKIIAKLLSKVNL-----TNYQNm 129
Cdd:COG4778 80 AQasprEIlalrRRTIGYVSQFLRVIPRVS---ALDVVAE----PLLERgvdreeaRARARELLARLNLperlwDLPPA- 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 544973757 130 kvkSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCE 178
Cdd:COG4778 152 ---TFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEE 197
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
4-167 |
7.99e-18 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 81.00 E-value: 7.99e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 4 KIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE---------- 72
Cdd:COG4598 8 ALEVRDLHKSFGDLEVLKGVSLTARKGdVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRLKPDrdgelvpadr 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 73 -----IRNMVGYLPQDFSMYPNMTVykamdyLAVLSDIPL----RKRRKIIAK---LLSKVNLTNYQNMKVKSLSGGMNR 140
Cdd:COG4598 88 rqlqrIRTRLGMVFQSFNLWSHMTV------LENVIEAPVhvlgRPKAEAIERaeaLLAKVGLADKRDAYPAHLSGGQQQ 161
|
170 180
....*....|....*....|....*..
gi 544973757 141 RLGIAQALIHNPRVLIVDEPTAGLDPE 167
Cdd:COG4598 162 RAAIARALAMEPEVMLFDEPTSALDPE 188
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
5-215 |
8.08e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 81.82 E-value: 8.08e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQ-----ALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGV------------- 65
Cdd:PRK13631 22 LRVKNLYCVFDEKQenelvALNNISYTFEKNkIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIyigdkknnhelit 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 66 -----PIENTKEIRNMVGYLPQ--DFSMYPNmTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNL-TNYQNMKVKSLSGG 137
Cdd:PRK13631 102 npyskKIKNFKELRRRVSMVFQfpEYQLFKD-TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLdDSYLERSPFGLSGG 180
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 138 MNRRLGIAQALIHNPRVLIVDEPTAGLDPE-ERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGS 215
Cdd:PRK13631 181 QKRRVAIAGILAIQPEILIFDEPTAGLDPKgEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGT 259
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
5-217 |
1.05e-17 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 80.65 E-value: 1.05e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIH-----------MCGVPIENTKE 72
Cdd:TIGR02323 4 LQVSGLSKSYGGGKGCRDVSFDLYPGeVLGIVGESGSGKSTLLGCLAGRLAPDHGTATyimrsgaelelYQLSEAERRRL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 73 IRNMVGYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIA---KLLSKVNL-TNYQNMKVKSLSGGMNRRLGIAQAL 148
Cdd:TIGR02323 84 MRTEWGFVHQNPRDGLRMRVSAGANIGERLMAIGARHYGNIRAtaqDWLEEVEIdPTRIDDLPRAFSGGMQQRLQIARNL 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544973757 149 IHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNGSTE 217
Cdd:TIGR02323 164 VTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLglAVIIVTHDLGVARLLAQRLLVMQQGRVVESGLTD 234
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
5-229 |
2.46e-17 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 79.20 E-value: 2.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQ--ALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK--EIRNMVGY 79
Cdd:cd03251 1 VEFKNVTFRYPGDGppVLRDISLDIPAGeTVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTlaSLRRQIGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQDFSMYpNMTVYKAMDYLAvlsdipLRKRRKIIAKLLSKVNLTNY-QNMK-----------VKsLSGGMNRRLGIAQA 147
Cdd:cd03251 81 VSQDVFLF-NDTVAENIAYGR------PGATREEVEEAARAANAHEFiMELPegydtvigergVK-LSGGQRQRIAIARA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 148 LIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVaILDSGKVIYNGSTEALakLAEGKV 227
Cdd:cd03251 153 LLKDPPILILDEATSALDTESERLVQAALERLMKNRTTFVIAHRLSTIENADRIV-VLEDGKIVERGTHEEL--LAQGGV 229
|
..
gi 544973757 228 YS 229
Cdd:cd03251 230 YA 231
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
7-165 |
2.66e-17 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 81.60 E-value: 2.66e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRfgkkQALDNINLEIDSG----MFGLLGrngAGKTTFMRILATLLSKTEGSIHMCG--VPIENTKE-IRNMVGY 79
Cdd:COG1129 259 VEGLSVG----GVVRDVSFSVRAGeilgIAGLVG---AGRTELARALFGADPADSGEIRLDGkpVRIRSPRDaIRAGIAY 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQD---------FSMYPNMTvykamdyLAVLSD------IPLRKRRKIIAKLLSKVNL-TNYQNMKVKSLSGGMNRRLG 143
Cdd:COG1129 332 VPEDrkgeglvldLSIRENIT-------LASLDRlsrgglLDRRRERALAEEYIKRLRIkTPSPEQPVGNLSGGNQQKVV 404
|
170 180
....*....|....*....|..
gi 544973757 144 IAQALIHNPRVLIVDEPTAGLD 165
Cdd:COG1129 405 LAKWLATDPKVLILDEPTRGID 426
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
18-228 |
2.95e-17 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 78.74 E-value: 2.95e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 18 QALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGYLPQDFSMYpNMTVYK 94
Cdd:cd03249 17 PILKGLSLTIPPGKTvALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRdlNLRWLRSQIGLVSQEPVLF-DGTIAE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 95 AMDY---LAVLSDIPLRKRRKIIAKLLSKvnLTN-YQNM---KVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE 167
Cdd:cd03249 96 NIRYgkpDATDEEVEEAAKKANIHDFIMS--LPDgYDTLvgeRGSQLSGGQKQRIAIARALLRNPKILLLDEATSALDAE 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544973757 168 ERIRFRNLLCEIANDRIVILSTHIVGDIEAtCENVAILDSGKVIYNGSTEALakLAEGKVY 228
Cdd:cd03249 174 SEKLVQEALDRAMKGRTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQGTHDEL--MAQKGVY 231
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
1-224 |
5.39e-17 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 78.90 E-value: 5.39e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRF--GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI--ENTKEIRN 75
Cdd:PRK13635 2 KEEIIRVEHISFRYpdAATYALKDVSFSVYEGEWvAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLseETVWDVRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 76 MVGYLPQDfsmyPN-----MTVykAMDYLAVLSD--IPlrkRRKIIAKL---LSKVNLTNYQNMKVKSLSGGMNRRLGIA 145
Cdd:PRK13635 82 QVGMVFQN----PDnqfvgATV--QDDVAFGLENigVP---REEMVERVdqaLRQVGMEDFLNREPHRLSGGQKQRVAIA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 146 QALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEI-ANDRIVILS-THivgDIE--ATCENVAILDSGKVIYNGSTEALAK 221
Cdd:PRK13635 153 GVLALQPDIIILDEATSMLDPRGRREVLETVRQLkEQKGITVLSiTH---DLDeaAQADRVIVMNKGEILEEGTPEEIFK 229
|
...
gi 544973757 222 LAE 224
Cdd:PRK13635 230 SGH 232
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
5-210 |
6.10e-17 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 77.61 E-value: 6.10e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF-GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE-----IRNMV 77
Cdd:PRK10908 2 IRFEHVSKAYlGGRQALQGVTFHMRPGeMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNrevpfLRRQI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIV 157
Cdd:PRK10908 82 GMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLA 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 158 DEPTAGLDPEERIRFRNLLCEIanDRI---VILSTHIVGDIEATCENVAILDSGKV 210
Cdd:PRK10908 162 DEPTGNLDDALSEGILRLFEEF--NRVgvtVLMATHDIGLISRRSYRMLTLSDGHL 215
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
21-190 |
6.77e-17 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 77.15 E-value: 6.77e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 21 DNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEI--RNM--VGYLPqdfSMYPNMTVYKA 95
Cdd:PRK13538 18 SGLSFTLNAGeLVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEyhQDLlyLGHQP---GIKTELTALEN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 96 MDYLAVLSDIPlrkRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNL 175
Cdd:PRK13538 95 LRFYQRLHGPG---DDEALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVARLEAL 171
|
170
....*....|....*.
gi 544973757 176 LCE-IANDRIVILSTH 190
Cdd:PRK13538 172 LAQhAEQGGMVILTTH 187
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1-235 |
1.30e-16 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 79.48 E-value: 1.30e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKiavsNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLL--SKTEGSIHMCGVPIEnTKEIRNM- 76
Cdd:TIGR02633 2 LEMK----GIVKTFGGVKALDGIDLEVRPGeCVGLCGENGAGKSTLMKILSGVYphGTWDGEIYWSGSPLK-ASNIRDTe 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 ---VGYLPQDFSMYPNMTVYK------AMDYLAVLSDIPLRKRRkiIAKLLSKVNLTNYQNMK-VKSLSGGMNRRLGIAQ 146
Cdd:TIGR02633 77 ragIVIIHQELTLVPELSVAEniflgnEITLPGGRMAYNAMYLR--AKNLLRELQLDADNVTRpVGDYGGGQQQLVEIAK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 147 ALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIV-ILSTHIVGDIEATCENVAILDSGKVIyngSTEALAKLAEG 225
Cdd:TIGR02633 155 ALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVAcVYISHKLNEVKAVCDTICVIRDGQHV---ATKDMSTMSED 231
|
250
....*....|
gi 544973757 226 KVYSIEVDKK 235
Cdd:TIGR02633 232 DIITMMVGRE 241
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
7-214 |
1.87e-16 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 79.15 E-value: 1.87e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILAtllskteGSIH---MCGVPIEN----TKEIRNMVG 78
Cdd:PLN03211 71 ISDETRQIQERTILNGVTGMASPGEIlAVLGPSGSGKSTLLNALA-------GRIQgnnFTGTILANnrkpTKQILKRTG 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 79 YLPQDFSMYPNMTVYKAMDYLAVL-------SDIPLRKRRKIIAKL-LSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIH 150
Cdd:PLN03211 144 FVTQDDILYPHLTVRETLVFCSLLrlpksltKQEKILVAESVISELgLTKCENTIIGNSFIRGISGGERKRVSIAHEMLI 223
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 151 NPRVLIVDEPTAGLDPEERIRFRNLLCEIAND-RIVILSTHIVGD-IEATCENVAILDSGKVIYNG 214
Cdd:PLN03211 224 NPSLLILDEPTSGLDATAAYRLVLTLGSLAQKgKTIVTSMHQPSSrVYQMFDSVLVLSEGRCLFFG 289
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
5-221 |
2.33e-16 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 78.94 E-value: 2.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN-TKEIRNMVG-YL- 80
Cdd:PRK15439 12 LCARSISKQYSGVEVLKGIDFTLHAGeVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARlTPAKAHQLGiYLv 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLtnyqNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:PRK15439 92 PQEPLLFPNLSVKENILFGLPKRQASMQKMKQLLAALGCQLDL----DSSAGSLEVADRQIVEILRGLMRDSRILILDEP 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 544973757 161 TAGLDPEERIRF----RNLLCEIANdrIVILStHIVGDIEATCENVAILDSGKVIYNGSTEALAK 221
Cdd:PRK15439 168 TASLTPAETERLfsriRELLAQGVG--IVFIS-HKLPEIRQLADRISVMRDGTIALSGKTADLST 229
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-166 |
2.66e-16 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 76.46 E-value: 2.66e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI---ENTKEIRNM 76
Cdd:PRK11614 2 EKVMLSFDKVSAHYGKIQALHEVSLHINQGeIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDItdwQTAKIMREA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 VGYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRR-KIIAKLLSKVNLTNYQnmKVKSLSGGMNRRLGIAQALIHNPRVL 155
Cdd:PRK11614 82 VAIVPEGRRVFSRMTVEENLAMGGFFAERDQFQERiKWVYELFPRLHERRIQ--RAGTMSGGEQQMLAIGRALMSQPRLL 159
|
170
....*....|.
gi 544973757 156 IVDEPTAGLDP 166
Cdd:PRK11614 160 LLDEPSLGLAP 170
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
36-167 |
2.80e-16 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 75.66 E-value: 2.80e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 36 GRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNM--VGYLPqdfSMYPNMTVYKAMDYLAVLSDiplRKRRKI 113
Cdd:PRK13543 44 GDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGDRSRFMayLGHLP---GLKADLSTLENLHFLCGLHG---RRAKQM 117
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 544973757 114 IAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE 167
Cdd:PRK13543 118 PGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLE 171
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
4-214 |
3.20e-16 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 75.38 E-value: 3.20e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 4 KIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLS---KTEGSIHMCGVPIENTKEI-RNMVG 78
Cdd:cd03233 7 RNISFTTGKGRSKIPILKDFSGVVKPGeMVLVLGRPGSGCSTLLKALANRTEgnvSVEGDIHYNGIPYKEFAEKyPGEII 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 79 YLPQDFSMYPNMTVYKAMDYLAvlsdiplrkrrkiiakllskvNLTNYQNmkVKSLSGGMNRRLGIAQALIHNPRVLIVD 158
Cdd:cd03233 87 YVSEEDVHFPTLTVRETLDFAL---------------------RCKGNEF--VRGISGGERKRVSIAEALVSRASVLCWD 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 159 EPTAGLDPEERIRFRNLLCEIANdriVILSTHIVG------DIEATCENVAILDSGKVIYNG 214
Cdd:cd03233 144 NSTRGLDSSTALEILKCIRTMAD---VLKTTTFVSlyqasdEIYDLFDKVLVLYEGRQIYYG 202
|
|
| ProV |
COG4175 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
4-166 |
3.22e-16 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 77.84 E-value: 3.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 4 KIAVSNLSKRFGKKQ------------------------ALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEG 58
Cdd:COG4175 3 KIEVRNLYKIFGKRPeralklldqgkskdeilektgqtvGVNDASFDVEEGeIFVIMGLSGSGKSTLVRCLNRLIEPTAG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 59 SIHMCGVPIE--NTKEIRN-------MVGylpQDFSMYPNMTVykaMDYLAV---LSDIPLRKRRKIIAKLLSKVNLTNY 126
Cdd:COG4175 83 EVLIDGEDITklSKKELRElrrkkmsMVF---QHFALLPHRTV---LENVAFgleIQGVPKAERRERAREALELVGLAGW 156
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 544973757 127 QNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDP 166
Cdd:COG4175 157 EDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDP 196
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
4-211 |
3.37e-16 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 75.61 E-value: 3.37e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 4 KIAVSNLSKRF--GKKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVG 78
Cdd:cd03244 2 DIEFKNVSLRYrpNLPPVLKNISFSIKPGEkVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISkiGLHDLRSRIS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 79 YLPQD---FSmypnMTVYKAMDYLAVLSDiplrkrrKIIAKLLSKVNLTNYqnmkVKSLSGGMNRR-------------- 141
Cdd:cd03244 82 IIPQDpvlFS----GTIRSNLDPFGEYSD-------EELWQALERVGLKEF----VESLPGGLDTVveeggenlsvgqrq 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544973757 142 -LGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIeATCENVAILDSGKVI 211
Cdd:cd03244 147 lLCLARALLRKSKILVLDEATASVDPETDALIQKTIREAFKDCTVLTIAHRLDTI-IDSDRILVLDKGRVV 216
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
5-211 |
3.92e-16 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 76.26 E-value: 3.92e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRF---------GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-----EN 69
Cdd:PRK10419 4 LNVSGLSHHYahgglsgkhQHQTVLNNVSLSLKSGeTVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLaklnrAQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 70 TKEIRNMVGYLPQDF--SMYPNMTV----YKAMDYLAVLSDiplRKRRKIIAKLLSKVNLTNYQNMKV-KSLSGGMNRRL 142
Cdd:PRK10419 84 RKAFRRDIQMVFQDSisAVNPRKTVreiiREPLRHLLSLDK---AERLARASEMLRAVDLDDSVLDKRpPQLSGGQLQRV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544973757 143 GIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAN--DRIVILSTHIVGDIEATCENVAILDSGKVI 211
Cdd:PRK10419 161 CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQqfGTACLFITHDLRLVERFCQRVMVMDNGQIV 231
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
9-211 |
4.00e-16 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 78.03 E-value: 4.00e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 9 NLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKE-IRNMVGYLPQDF 84
Cdd:PRK11288 9 GIGKTFPGVKALDDISFDCRAGqVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRfaSTTAaLAAGVAIIYQEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 85 SMYPNMTVykaMDYLaVLSDIPLR----KRRKIIA---KLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIV 157
Cdd:PRK11288 89 HLVPEMTV---AENL-YLGQLPHKggivNRRLLNYearEQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAF 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 158 DEPTAGLD-PEERIRFRnLLCEI-ANDRIVILSTHIVGDIEATCENVAILDSGKVI 211
Cdd:PRK11288 165 DEPTSSLSaREIEQLFR-VIRELrAEGRVILYVSHRMEEIFALCDAITVFKDGRYV 219
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
5-230 |
4.54e-16 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 77.08 E-value: 4.54e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMrILATLLSKTEGS-----IHMCGvpieNTKEIRNMVG 78
Cdd:NF000106 14 VEVRGLVKHFGEVKAVDGVDLDVREGtVLGVLGP*GAA**RGA-LPAHV*GPDAGRrpwrf*TWCA----NRRALRRTIG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 79 -YLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIV 157
Cdd:NF000106 89 *HRPVR*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYL 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 544973757 158 DEPTAGLDPEERIRFRNLLCEIAND-RIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEALAKLAEGKVYSI 230
Cdd:NF000106 169 DEPTTGLDPRTRNEVWDEVRSMVRDgATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVGGRTLQI 242
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
5-190 |
5.94e-16 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 75.20 E-value: 5.94e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQA----LDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI-----ENTKEIR 74
Cdd:PRK10584 7 VEVHHLKKSVGQGEHelsiLTGVELVVKRGeTIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLhqmdeEARAKLR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 75 -NMVGYLPQDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPR 153
Cdd:PRK10584 87 aKHVGFVFQSFMLIPTLNALENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPD 166
|
170 180 190
....*....|....*....|....*....|....*....
gi 544973757 154 VLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTH 190
Cdd:PRK10584 167 VLFADEPTGNLDRQTGDKIADLLFSLNREHgtTLILVTH 205
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
4-211 |
6.68e-16 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 74.37 E-value: 6.68e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 4 KIAVSNLSKRFGKK--QALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK--EIRNMVG 78
Cdd:cd03369 6 EIEVENLSVRYAPDlpPVLKNVSFKVKAGeKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPleDLRSSLT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 79 YLPQDFSMYPNmTVYKAMDYLAVLSDIPLrkrrkiiakllskvnltnYQNMKVKS----LSGGMNRRLGIAQALIHNPRV 154
Cdd:cd03369 86 IIPQDPTLFSG-TIRSNLDPFDEYSDEEI------------------YGALRVSEgglnLSQGQRQLLCLARALLKRPRV 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 155 LIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIeATCENVAILDSGKVI 211
Cdd:cd03369 147 LVLDEATASIDYATDALIQKTIREEFTNSTILTIAHRLRTI-IDYDKILVMDAGEVK 202
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
8-165 |
1.35e-15 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 74.08 E-value: 1.35e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 8 SNLSKRF--GKKQA--LDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE-----NTKEIRNM- 76
Cdd:PRK11629 9 DNLCKRYqeGSVQTdvLHNVSFSIGEGeMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSklssaAKAELRNQk 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 VGYLPQDFSMYPNMTvykAMDYLAVLSDIPLRKRRKIIAK---LLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPR 153
Cdd:PRK11629 89 LGFIYQFHHLLPDFT---ALENVAMPLLIGKKKPAEINSRaleMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPR 165
|
170
....*....|..
gi 544973757 154 VLIVDEPTAGLD 165
Cdd:PRK11629 166 LVLADEPTGNLD 177
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
2-171 |
1.74e-15 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 76.39 E-value: 1.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 2 EMKIAVSNLSKRFGkkqaldNINLEIDSG------MFGLLGRNGAGKTTFMRILATLLSKTEGSIhmcgvpienTKEIRn 75
Cdd:PRK13409 338 ETLVEYPDLTKKLG------DFSLEVEGGeiyegeVIGIVGPNGIGKTTFAKLLAGVLKPDEGEV---------DPELK- 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 76 mVGYLPQDFSMYPNMTVYkamdylAVLSDIPLRKRRKII-AKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRV 154
Cdd:PRK13409 402 -ISYKPQYIKPDYDGTVE------DLLRSITDDLGSSYYkSEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADL 474
|
170
....*....|....*..
gi 544973757 155 LIVDEPTAGLDPEERIR 171
Cdd:PRK13409 475 YLLDEPSAHLDVEQRLA 491
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
5-215 |
1.87e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 74.66 E-value: 1.87e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKK-----QALDNINLEI-DSGMFGLLGRNGAGKTTFMRILATLLSKTEGS--IHMCGVP-----IENTK 71
Cdd:PRK13645 7 IILDNVSYTYAKKtpfefKALNNTSLTFkKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQtiVGDYAIPanlkkIKEVK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 72 EIRNMVGYLPQ--DFSMYPNmTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNL-TNYQNMKVKSLSGGMNRRLGIAQAL 148
Cdd:PRK13645 87 RLRKEIGLVFQfpEYQLFQE-TIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGII 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 149 IHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAND--RIVILSTHIVGDIEATCENVAILDSGKVIYNGS 215
Cdd:PRK13645 166 AMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEykKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGS 234
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
10-219 |
2.62e-15 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 75.49 E-value: 2.62e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 10 LSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSkTEGSIHMCGVPIE--NTKEIRnmvgylP----- 81
Cdd:COG4172 292 FRRTVGHVKAVDGVSLTLRRGeTLGLVGESGSGKSTLGLALLRLIP-SEGEIRFDGQDLDglSRRALR------Plrrrm 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 ----QD-F-SMYPNMTVykamdylavlSDI---PLR---------KRRKIIAKLLSKVNLT-NYQNMKVKSLSGGMNRRL 142
Cdd:COG4172 365 qvvfQDpFgSLSPRMTV----------GQIiaeGLRvhgpglsaaERRARVAEALEEVGLDpAARHRYPHEFSGGQRQRI 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 143 GIAQALIHNPRVLIVDEPTAGLDpeeR-IRFR--NLLCEIANDR----IVIlsTHIVGDIEATCENVAILDSGKVIYNGS 215
Cdd:COG4172 435 AIARALILEPKLLVLDEPTSALD---VsVQAQilDLLRDLQREHglayLFI--SHDLAVVRALAHRVMVMKDGKVVEQGP 509
|
....
gi 544973757 216 TEAL 219
Cdd:COG4172 510 TEQV 513
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
4-173 |
4.08e-15 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 74.49 E-value: 4.08e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 4 KIAVSNLSKRF-GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIeNTKEIRN----MV 77
Cdd:PRK11650 3 GLKLQAVRKSYdGKTQVIKGIDLDVADGEFiVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVV-NELEPADrdiaMV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GylpQDFSMYPNMTVYKAMDY---LAVLSDIPLRKRRKIIAKLLskvNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRV 154
Cdd:PRK11650 82 F---QNYALYPHMSVRENMAYglkIRGMPKAEIEERVAEAARIL---ELEPLLDRKPRELSGGQRQRVAMGRAIVREPAV 155
|
170
....*....|....*....
gi 544973757 155 LIVDEPTAGLDPEERIRFR 173
Cdd:PRK11650 156 FLFDEPLSNLDAKLRVQMR 174
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
5-243 |
5.45e-15 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 73.15 E-value: 5.45e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEI-DSGMFGLLGRNGAGKTTFMRILATLLS-----KTEGSIHMCGVPIE----NTKEIR 74
Cdd:PRK14258 8 IKVNNLSFYYDTQKILEGVSMEIyQSKVTAIIGPSGCGKSTFLKCLNRMNElesevRVEGRVEFFNQNIYerrvNLNRLR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 75 NMVGYLPQDFSMYPnMTVYKAMDY-LAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKV-KS---LSGGMNRRLGIAQALI 149
Cdd:PRK14258 88 RQVSMVHPKPNLFP-MSVYDNVAYgVKIVGWRPKLEIDDIVESALKDADLWDEIKHKIhKSaldLSGGQQQRLCIARALA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 150 HNPRVLIVDEPTAGLDPEERIRFRNLL--CEIANDRIVILSTHIVGDIEATCENVAildsgkvIYNGSTEALAKLAE--- 224
Cdd:PRK14258 167 VKPKVLLMDEPCFGLDPIASMKVESLIqsLRLRSELTMVIVSHNLHQVSRLSDFTA-------FFKGNENRIGQLVEfgl 239
|
250 260
....*....|....*....|
gi 544973757 225 -GKVYSIEVDKKDIENIKSR 243
Cdd:PRK14258 240 tKKIFNSPHDSRTREYVLSR 259
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
17-229 |
5.63e-15 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 74.67 E-value: 5.63e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 17 KQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK--EIRNMVGYLPQDFSMYpNMTVY 93
Cdd:PRK11176 356 VPALRNINFKIPAGkTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTlaSLRNQVALVSQNVHLF-NDTIA 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 94 KAMDYLAvlSDIPLRKRRKIIAKLLSKVNLTNyqnmKVK------------SLSGGMNRRLGIAQALIHNPRVLIVDEPT 161
Cdd:PRK11176 435 NNIAYAR--TEQYSREQIEEAARMAYAMDFIN----KMDngldtvigengvLLSGGQRQRIAIARALLRDSPILILDEAT 508
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 162 AGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAIlDSGKVIYNGSTEALakLAEGKVYS 229
Cdd:PRK11176 509 SALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEILVV-EDGEIVERGTHAEL--LAQNGVYA 573
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
20-223 |
5.67e-15 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 74.76 E-value: 5.67e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 20 LDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEI----RNMVGYLPQDFSMYPNMTV 92
Cdd:PRK10535 24 LKGISLDIYAGeMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVAtlDADALaqlrREHFGFIFQRYHLLSHLTA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 93 YKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDP---EER 169
Cdd:PRK10535 104 AQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDShsgEEV 183
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 544973757 170 IRFRNLLCEiaNDRIVILSTHiVGDIEATCENVAILDSGKVIYNGSTEALAKLA 223
Cdd:PRK10535 184 MAILHQLRD--RGHTVIIVTH-DPQVAAQAERVIEIRDGEIVRNPPAQEKVNVA 234
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
15-222 |
8.99e-15 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 73.92 E-value: 8.99e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 15 GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGYLPQDFSMYPNmT 91
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEAlAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKqwDRETFGKHIGYLPQDVELFPG-T 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 92 VYKAmdyLAVLSDIPlrKRRKII-AKLLSKV-----NLTNYQNMKV----KSLSGGMNRRLGIAQALIHNPRVLIVDEPT 161
Cdd:TIGR01842 408 VAEN---IARFGENA--DPEKIIeAAKLAGVhelilRLPDGYDTVIgpggATLSGGQRQRIALARALYGDPKLVVLDEPN 482
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544973757 162 AGLDPEERIRFRNLLCEI-ANDRIVILSTHIVGDIEATcENVAILDSGKV-IYNGSTEALAKL 222
Cdd:TIGR01842 483 SNLDEEGEQALANAIKALkARGITVVVITHRPSLLGCV-DKILVLQDGRIaRFGERDEVLAKL 544
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
20-176 |
9.41e-15 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 70.26 E-value: 9.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 20 LDNINLEIDSGMFGLL-GRNGAGKTTFMRILATLLSKTEGSIHMCGvpientkeiRNMVGYLPQDfsmyPnmtvykamdY 98
Cdd:cd03223 17 LKDLSFEIKPGDRLLItGPSGTGKSSLFRALAGLWPWGSGRIGMPE---------GEDLLFLPQR----P---------Y 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 99 LAVLSdipLRKrrkIIAKLLSKVnltnyqnmkvksLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLL 176
Cdd:cd03223 75 LPLGT---LRE---QLIYPWDDV------------LSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQLL 134
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
6-210 |
9.77e-15 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 70.54 E-value: 9.77e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 6 AVSNLSKrfgkKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE---NTKEIRNMVGYLP 81
Cdd:cd03215 6 EVRGLSV----KGAVRDVSFEVRAGeIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTrrsPRDAIRAGIAYVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QDfsmypnmtvykamdylavlsdiplRKRRKIIAkllskvNLTNYQNMKVKS-LSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:cd03215 82 ED------------------------RKREGLVL------DLSVAENIALSSlLSGGNQQKVVLARWLARDPRVLILDEP 131
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 544973757 161 TAGLDPEERIRFRNLLCEIANDR--IVILSThivgDIE---ATCENVAILDSGKV 210
Cdd:cd03215 132 TRGVDVGAKAEIYRLIRELADAGkaVLLISS----ELDellGLCDRILVMYEGRI 182
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1-210 |
1.20e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 72.46 E-value: 1.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQ---ALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCG--VPIENTKEIR 74
Cdd:PRK13650 1 MSNIIEVKNLTFKYKEDQekyTLNDVSFHVKQGeWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGdlLTEENVWDIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 75 NMVGYLPQD-FSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPR 153
Cdd:PRK13650 81 HKIGMVFQNpDNQFVGATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPK 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 154 VLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIeATCENVAILDSGKV 210
Cdd:PRK13650 161 IIILDEATSMLDPEGRLELIKTIKGIRDDYqmTVISITHDLDEV-ALSDRVLVMKNGQV 218
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-219 |
1.31e-14 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 71.73 E-value: 1.31e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEI-DSGMFGLLGRNGAGKTTFMRILATLLS-----KTEGSI----HMCGVPIENT 70
Cdd:PRK14239 2 TEPILQVSDLSVYYNKKKALNSVSLDFyPNEITALIGPSGSGKSTLLRSINRMNDlnpevTITGSIvyngHNIYSPRTDT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 71 KEIRNMVGYLPQDFSMYPnMTVYKAMDYLAVLSDIPLRKR-RKIIAKLLSKVNLTNyqnmKVK--------SLSGGMNRR 141
Cdd:PRK14239 82 VDLRKEIGMVFQQPNPFP-MSIYENVVYGLRLKGIKDKQVlDEAVEKSLKGASIWD----EVKdrlhdsalGLSGGQQQR 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 142 LGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK14239 157 VCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQM 234
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
17-217 |
1.43e-14 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 72.98 E-value: 1.43e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 17 KQALDNINLEID-----SGMFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCG---VPIEN----TKEIRNmVGYLPQDF 84
Cdd:PRK11144 7 KQQLGDLCLTVNltlpaQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGrvlFDAEKgiclPPEKRR-IGYVFQDA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 85 SMYPNMTV-----Y---KAM----DYLAVLSDI-PLRKRRKIiakllskvnltnyqnmkvkSLSGGMNRRLGIAQALIHN 151
Cdd:PRK11144 86 RLFPHYKVrgnlrYgmaKSMvaqfDKIVALLGIePLLDRYPG-------------------SLSGGEKQRVAIGRALLTA 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 152 PRVLIVDEPTAGLD-PeeriRFRNL---LCEIAND-RIVIL-STHIVGDIEATCENVAILDSGKVIYNGSTE 217
Cdd:PRK11144 147 PELLLMDEPLASLDlP----RKRELlpyLERLAREiNIPILyVSHSLDEILRLADRVVVLEQGKVKAFGPLE 214
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
1-227 |
1.86e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 71.66 E-value: 1.86e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNIN---LEIDSGMF-GLLGRNGAGKTTFMRILATLLSKTEGSIHMCG--VPIENTKEIR 74
Cdd:PRK13642 1 MNKILEVENLVFKYEKESDVNQLNgvsFSITKGEWvSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGelLTAENVWNLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 75 NMVGYLPQD-FSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPR 153
Cdd:PRK13642 81 RKIGMVFQNpDNQFVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPE 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 544973757 154 VLIVDEPTAGLDPEERIRFRNLLCEIAND-RIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEALAKLAEGKV 227
Cdd:PRK13642 161 IIILDESTSMLDPTGRQEIMRVIHEIKEKyQLTVLSITHDLDEAASSDRILVMKAGEIIKEAAPSELFATSEDMV 235
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
16-171 |
2.46e-14 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 70.90 E-value: 2.46e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 16 KKQALDNINLEIDSGMF------GLLGRNGAGKTTFMRILATLLSKTEGSIhmcgvPIENTKeirnmVGYLPQDFSMYPN 89
Cdd:cd03237 6 MKKTLGEFTLEVEGGSIseseviGILGPNGIGKTTFIKMLAGVLKPDEGDI-----EIELDT-----VSYKPQYIKADYE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 90 MTVYkamdylAVLSDIPLRKR-----RKIIAKLLSKVNLTNYQnmkVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGL 164
Cdd:cd03237 76 GTVR------DLLSSITKDFYthpyfKTEIAKPLQIEQILDRE---VPELSGGELQRVAIAACLSKDADIYLLDEPSAYL 146
|
....*..
gi 544973757 165 DPEERIR 171
Cdd:cd03237 147 DVEQRLM 153
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
18-210 |
2.59e-14 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 70.58 E-value: 2.59e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 18 QALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK-----EIRNMVGYLPQDFSMypnmT 91
Cdd:cd03248 28 LVLQDVSFTLHPGeVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEhkylhSKVSLVGQEPVLFAR----S 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 92 VYKAMDYlaVLSDIPLRKrrkiIAKLLSKVNL-TNYQNM----------KVKSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:cd03248 104 LQDNIAY--GLQSCSFEC----VKEAAQKAHAhSFISELasgydtevgeKGSQLSGGQKQRVAIARALIRNPQVLILDEA 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 544973757 161 TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATcENVAILDSGKV 210
Cdd:cd03248 178 TSALDAESEQQVQQALYDWPERRTVLVIAHRLSTVERA-DQILVLDGGRI 226
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
8-171 |
3.68e-14 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 72.12 E-value: 3.68e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 8 SNLSKRFGkkqaldNINLEIDSGMF------GLLGRNGAGKTTFMRILATLLSKTEGSIHMcgvpientkEIRnmVGYLP 81
Cdd:COG1245 345 PDLTKSYG------GFSLEVEGGEIregevlGIVGPNGIGKTTFAKILAGVLKPDEGEVDE---------DLK--ISYKP 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QDFSMYPNMTVykaMDYL--AVLSDIPLRKRRKIIAKLLskvNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDE 159
Cdd:COG1245 408 QYISPDYDGTV---EEFLrsANTDDFGSSYYKTEIIKPL---GLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDE 481
|
170
....*....|..
gi 544973757 160 PTAGLDPEERIR 171
Cdd:COG1245 482 PSAHLDVEQRLA 493
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-219 |
6.44e-14 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 71.64 E-value: 6.44e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMK--IAVSNLSKRFGK----KQALDNINLEIDSG-MFGLLGRNGAGKT----TFMRILATLLSKTEGSIHMCGVPIEN 69
Cdd:COG4172 1 MMSMplLSVEDLSVAFGQgggtVEAVKGVSFDIAAGeTLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 70 TKE-----IR-NMVGYLPQD--FSMYPNMTVYKAM-DYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNmKVKS----LSG 136
Cdd:COG4172 81 LSErelrrIRgNRIAMIFQEpmTSLNPLHTIGKQIaEVLRLHRGLSGAAARARALELLERVGIPDPER-RLDAyphqLSG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 137 GMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTH---IVGDIeatCENVAILDSGKVI 211
Cdd:COG4172 160 GQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELgmALLLITHdlgVVRRF---ADRVAVMRQGEIV 236
|
....*...
gi 544973757 212 YNGSTEAL 219
Cdd:COG4172 237 EQGPTAEL 244
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
7-167 |
7.69e-14 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 71.46 E-value: 7.69e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCgvpiENTKeirnmVGYLPQDFS 85
Cdd:PRK15064 322 VENLTKGFDNGPLFKNLNLLLEAGeRLAIIGENGVGKTTLLRTLVGELEPDSGTVKWS----ENAN-----IGYYAQDHA 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 86 -MYPN-MTVYKAM--------DYLAVlsdiplrkrRKIIAKLL-SKVNLtnyqNMKVKSLSGGMNRRLGIAQALIHNPRV 154
Cdd:PRK15064 393 yDFENdLTLFDWMsqwrqegdDEQAV---------RGTLGRLLfSQDDI----KKSVKVLSGGEKGRMLFGKLMMQKPNV 459
|
170
....*....|...
gi 544973757 155 LIVDEPTAGLDPE 167
Cdd:PRK15064 460 LVMDEPTNHMDME 472
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
18-179 |
9.50e-14 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 70.12 E-value: 9.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 18 QALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSI-----HMCGVPIENTKEIRNMVGYLPQD--FSMYPN 89
Cdd:PRK15079 35 KAVDGVTLRLYEGeTLGVVGESGCGKSTFARAIIGLVKATDGEVawlgkDLLGMKDDEWRAVRSDIQMIFQDplASLNPR 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 90 MTVykamdylavlSDI---PLR------KRRKIIAK---LLSKVNL-TNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLI 156
Cdd:PRK15079 115 MTI----------GEIiaePLRtyhpklSRQEVKDRvkaMMLKVGLlPNLINRYPHEFSGGQCQRIGIARALILEPKLII 184
|
170 180
....*....|....*....|...
gi 544973757 157 VDEPTAGLDPEERIRFRNLLCEI 179
Cdd:PRK15079 185 CDEPVSALDVSIQAQVVNLLQQL 207
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
1-220 |
1.03e-13 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 69.43 E-value: 1.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKK---------QALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE-- 68
Cdd:PRK15112 1 VETLLEVRNLSKTFRYRtgwfrrqtvEAVKPLSFTLREGQtLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHfg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 69 ----NTKEIRnMVGYLPQDfSMYPNMTVYKAMDY-LAVLSDIPLRKRRKIIAKLLSKVNL-TNYQNMKVKSLSGGMNRRL 142
Cdd:PRK15112 81 dysyRSQRIR-MIFQDPST-SLNPRQRISQILDFpLRLNTDLEPEQREKQIIETLRQVGLlPDHASYYPHMLAPGQKQRL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 143 GIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIV--ILSTHIVGDIEATCENVAILDSGKVIYNGST-EAL 219
Cdd:PRK15112 159 GLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGIsyIYVTQHLGMMKHISDQVLVMHQGEVVERGSTaDVL 238
|
.
gi 544973757 220 A 220
Cdd:PRK15112 239 A 239
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
24-219 |
1.23e-13 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 68.84 E-value: 1.23e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 24 NLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAmdyLAVL 102
Cdd:PRK10771 19 DLTVERGeRVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRPVSMLFQENNLFSHLTVAQN---IGLG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 103 SDIPLR---KRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEI 179
Cdd:PRK10771 96 LNPGLKlnaAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQV 175
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 544973757 180 ANDRIVIL--STHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK10771 176 CQERQLTLlmVSHSLEDAARIAPRSLVVADGRIAWDGPTDEL 217
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
13-205 |
1.53e-13 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 68.20 E-value: 1.53e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 13 RFGKKQALDNINLEIDSGMFGLL-GRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGYLPQDFSMYPN 89
Cdd:PRK10247 16 LAGDAKILNNISFSLRAGEFKLItGPSGCGKSTLLKIVASLISPTSGTLLFEGEDIStlKPEIYRQQVSYCAQTPTLFGD 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 90 mTVYkamDYLAVLSDIplRKRR---KIIAKLLSKVNL-TNYQNMKVKSLSGGMNRRLgiaqALIHN----PRVLIVDEPT 161
Cdd:PRK10247 96 -TVY---DNLIFPWQI--RNQQpdpAIFLDDLERFALpDTILTKNIAELSGGEKQRI----SLIRNlqfmPKVLLLDEIT 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 544973757 162 AGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIeATCENVAIL 205
Cdd:PRK10247 166 SALDESNKHNVNEIIHRYVREQniAVLWVTHDKDEI-NHADKVITL 210
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
8-232 |
2.00e-13 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 70.14 E-value: 2.00e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 8 SNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKE-IRNMVGYLPQD 83
Cdd:PRK10982 2 SNISKSFPGVKALDNVNLKVRPHsIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDfkSSKEaLENGISMVHQE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVykaMDYL----------AVLSDIPLRKRRKIIAKLLSKVNltnyQNMKVKSLSGGMNRRLGIAQALIHNPR 153
Cdd:PRK10982 82 LNLVLQRSV---MDNMwlgryptkgmFVDQDKMYRDTKAIFDELDIDID----PRAKVATLSVSQMQMIEIAKAFSYNAK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 154 VLIVDEPTAGLDPEErirfRNLLCEIAN---DR---IVILStHIVGDIEATCENVAILDSGKVIyngSTEALAKLAEGKV 227
Cdd:PRK10982 155 IVIMDEPTSSLTEKE----VNHLFTIIRklkERgcgIVYIS-HKMEEIFQLCDEITILRDGQWI---ATQPLAGLTMDKI 226
|
....*
gi 544973757 228 YSIEV 232
Cdd:PRK10982 227 IAMMV 231
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
16-215 |
2.34e-13 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 70.14 E-value: 2.34e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 16 KKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILAtllSKTEGS-------IHMCGVPIEN-TKEIRNMVGYLPQDFSM 86
Cdd:TIGR00956 73 TFDILKPMDGLIKPGeLTVVLGRPGSGCSTLLKTIA---SNTDGFhigvegvITYDGITPEEiKKHYRGDVVYNAETDVH 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 87 YPNMTVYKAMDYLAVLSDIPLRKR---RKIIAKLLSKVNLTNY-----QNMKV-----KSLSGGMNRRLGIAQALIHNPR 153
Cdd:TIGR00956 150 FPHLTVGETLDFAARCKTPQNRPDgvsREEYAKHIADVYMATYglshtRNTKVgndfvRGVSGGERKRVSIAEASLGGAK 229
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 154 VLIVDEPTAGLDPEERIRFRNLLCEIANdrivIL-STHIVG------DIEATCENVAILDSGKVIYNGS 215
Cdd:TIGR00956 230 IQCWDNATRGLDSATALEFIRALKTSAN----ILdTTPLVAiyqcsqDAYELFDKVIVLYEGYQIYFGP 294
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
5-219 |
2.80e-13 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 68.25 E-value: 2.80e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK-----EIRNMVG 78
Cdd:PRK11831 8 VDMRGVSFTRGNRCIFDNISLTVPRGkITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSrsrlyTVRKRMS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 79 YLPQDFSMYPNMTVYKAMDYlavlsdiPLRKRRKIIAKL--------LSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIH 150
Cdd:PRK11831 88 MLFQSGALFTDMNVFDNVAY-------PLREHTQLPAPLlhstvmmkLEAVGLRGAAKLMPSELSGGMARRAALARAIAL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544973757 151 NPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIV--ILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK11831 161 EPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVtcVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL 231
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
19-219 |
3.10e-13 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 69.50 E-value: 3.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 19 ALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN-----TKEIRNMVGYLPQD--FSMYPNM 90
Cdd:PRK10261 339 AVEKVSFDLWPGeTLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTlspgkLQALRRDIQFIFQDpyASLDPRQ 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 91 TV-YKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKV-KSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEE 168
Cdd:PRK10261 419 TVgDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPEHAWRYpHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSI 498
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 544973757 169 RIRFRNLLCEIANDRIV--ILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK10261 499 RGQIINLLLDLQRDFGIayLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAV 551
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
16-229 |
3.18e-13 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 69.75 E-value: 3.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 16 KKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGYLPQDFSMYpNMTV 92
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGeVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVqyDHHYLHRQVALVGQEPVLF-SGSV 571
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 93 YKAMDYlaVLSDIPLRKRRKIIAKLLSKVNLTNYQN-------MKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLD 165
Cdd:TIGR00958 572 RENIAY--GLTDTPDEEIMAAAKAANAHDFIMEFPNgydtevgEKGSQLSGGQKQRIAIARALVRKPRVLILDEATSALD 649
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 544973757 166 PEERIRFRNLLCeiANDRIVILSTHIVGDIEaTCENVAILDSGKVIYNGSTEALakLAEGKVYS 229
Cdd:TIGR00958 650 AECEQLLQESRS--RASRTVLLIAHRLSTVE-RADQILVLKKGSVVEMGTHKQL--MEDQGCYK 708
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
9-167 |
3.68e-13 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 69.19 E-value: 3.68e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 9 NLSKRF-GKKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLLSKTEGSIhmcgVPIENTKeirnmVGYLPQDFSM 86
Cdd:TIGR03719 9 RVSKVVpPKKEILKDISLSFFPGAkIGVLGLNGAGKSTLLRIMAGVDKDFNGEA----RPQPGIK-----VGYLPQEPQL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 87 YPNMTVY--------KAMDYLAVLSDI------PLRKRRKII---AKLLSKVNLTNYQNM------------------KV 131
Cdd:TIGR03719 80 DPTKTVRenveegvaEIKDALDRFNEIsakyaePDADFDKLAaeqAELQEIIDAADAWDLdsqleiamdalrcppwdaDV 159
|
170 180 190
....*....|....*....|....*....|....*.
gi 544973757 132 KSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE 167
Cdd:TIGR03719 160 TKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAE 195
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
4-219 |
3.74e-13 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 67.96 E-value: 3.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 4 KIAVSNLSKRF--GKKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLLSkTEGSIHMCGVPIENT--KEIRNMVG 78
Cdd:cd03289 2 QMTVKDLTAKYteGGNAVLENISFSISPGQrVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSWNSVplQKWRKAFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 79 YLPQDFSMYPNmTVYKAMDYLAVLSDIPLRK------RRKIIAKLLSKVNLTNYQNMKVksLSGGMNRRLGIAQALIHNP 152
Cdd:cd03289 81 VIPQKVFIFSG-TFRKNLDPYGKWSDEEIWKvaeevgLKSVIEQFPGQLDFVLVDGGCV--LSHGHKQLMCLARSVLSKA 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 153 RVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHivgDIEAT--CENVAILDSGKVIYNGSTEAL 219
Cdd:cd03289 158 KILLLDEPSAHLDPITYQVIRKTLKQAFADCTVILSEH---RIEAMleCQRFLVIEENKVRQYDSIQKL 223
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1-211 |
4.14e-13 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 68.88 E-value: 4.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 1 MEMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCG--VPIENTKEIRNM- 76
Cdd:PRK10762 1 MQALLQLKGIDKAFPGVKALSGAALNVYPGrVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGkeVTFNGPKSSQEAg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 VGYLPQDFSMYPNMTV----YKAMDYLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNP 152
Cdd:PRK10762 81 IGIIHQELNLIPQLTIaeniFLGREFVNRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFES 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 153 RVLIVDEPTAGL-DPEERIRFRnLLCEIANDR--IVILStHIVGDIEATCENVAILDSGKVI 211
Cdd:PRK10762 161 KVIIMDEPTDALtDTETESLFR-VIRELKSQGrgIVYIS-HRLKEIFEICDDVTVFRDGQFI 220
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
7-210 |
4.18e-13 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 69.55 E-value: 4.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRF--GKKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLLSkTEGSIHMCGVPIENT--KEIRNMVGYLP 81
Cdd:TIGR01271 1220 VQGLTAKYteAGRAVLQDLSFSVEGGQrVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGVSWNSVtlQTWRKAFGVIP 1298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QDFSMYPNmTVYKAMDYLAVLSDIPLRK------RRKIIAKLLSKVNLTNYQNMKVksLSGGMNRRLGIAQALIHNPRVL 155
Cdd:TIGR01271 1299 QKVFIFSG-TFRKNLDPYEQWSDEEIWKvaeevgLKSVIEQFPDKLDFVLVDGGYV--LSNGHKQLMCLARSILSKAKIL 1375
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 156 IVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTHivgDIEA--TCENVAILDSGKV 210
Cdd:TIGR01271 1376 LLDEPSAHLDPVTLQIIRKTLKQSFSNCTVILSEH---RVEAllECQQFLVIEGSSV 1429
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
5-191 |
4.94e-13 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 68.81 E-value: 4.94e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEI-DSGMFGLLGRNGAGKTTFMRILATLLSKTEGSIHMcGvpiENTKeirnmVGYLPQ- 82
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLpPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-G---ETVK-----LAYVDQs 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 -DfSMYPNMTVYKAM----DYLAVLS-DIPLRkrrkiiaKLLSKVNLT-NYQNMKVKSLSGGMNRRLGIAQALIHNPRVL 155
Cdd:TIGR03719 394 rD-ALDPNKTVWEEIsgglDIIKLGKrEIPSR-------AYVGRFNFKgSDQQKKVGQLSGGERNRVHLAKTLKSGGNVL 465
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 544973757 156 IVDEPTAGLDPEERIRFRNLLCEIANDRIVI---------LSTHI 191
Cdd:TIGR03719 466 LLDEPTNDLDVETLRALEEALLNFAGCAVVIshdrwfldrIATHI 510
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
5-209 |
5.89e-13 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 66.34 E-value: 5.89e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQ-----ALDNINLEIDSGMF-GLLGRNGAGKTTFmrILATL--LSKTEGSIHMCGvpientkeirnM 76
Cdd:cd03250 1 ISVEDASFTWDSGEqetsfTLKDINLEVPKGELvAIVGPVGSGKSSL--LSALLgeLEKLSGSVSVPG-----------S 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 VGYLPQdFSMYPNMTV---------YKAMDYLAVLSDIPLRKRRKIiaklLSKVNLTNYQNMKVkSLSGGMNRRLGIAQA 147
Cdd:cd03250 68 IAYVSQ-EPWIQNGTIrenilfgkpFDEERYEKVIKACALEPDLEI----LPDGDLTEIGEKGI-NLSGGQKQRISLARA 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 544973757 148 LIHNPRVLIVDEPTAGLDP--EERIrFRNLLC-EIANDRIVILSTHIVGDIEAtCENVAILDSGK 209
Cdd:cd03250 142 VYSDADIYLLDDPLSAVDAhvGRHI-FENCILgLLLNNKTRILVTHQLQLLPH-ADQIVVLDNGR 204
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
34-214 |
6.91e-13 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 68.72 E-value: 6.91e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 34 LLGRNGAGKTTFMRILATllSKT----EGSIHMCGVPiENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL---SDIP 106
Cdd:PLN03140 911 LMGVSGAGKTTLMDVLAG--RKTggyiEGDIRISGFP-KKQETFARISGYCEQNDIHSPQVTVRESLIYSAFLrlpKEVS 987
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 107 LRKRRKIIAKLLSKVNLTNYQNM-----KVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE-ERIRFRNLLCEIA 180
Cdd:PLN03140 988 KEEKMMFVDEVMELVELDNLKDAivglpGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARaAAIVMRTVRNTVD 1067
|
170 180 190
....*....|....*....|....*....|....*.
gi 544973757 181 NDRIVILSTHIVG-DI-EATCENVAILDSGKVIYNG 214
Cdd:PLN03140 1068 TGRTVVCTIHQPSiDIfEAFDELLLMKRGGQVIYSG 1103
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
20-190 |
1.74e-12 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 67.14 E-value: 1.74e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 20 LDNINLEIDSGMfGLL--GRNGAGKTTFMRILATLLSKTEGSIHMcgvPientkEIRNMVgYLPQdfSMY-PNMTVYKAM 96
Cdd:COG4178 379 LEDLSLSLKPGE-RLLitGPSGSGKSTLLRAIAGLWPYGSGRIAR---P-----AGARVL-FLPQ--RPYlPLGTLREAL 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 97 DYLAVLSDIPlrkrRKIIAKLLSKVNLTNYQNM--------KVksLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEE 168
Cdd:COG4178 447 LYPATAEAFS----DAELREALEAVGLGHLAERldeeadwdQV--LSLGEQQRLAFARLLLHKPDWLFLDEATSALDEEN 520
|
170 180
....*....|....*....|..
gi 544973757 169 RIRFRNLLCEIANDRIVILSTH 190
Cdd:COG4178 521 EAALYQLLREELPGTTVISVGH 542
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
4-223 |
1.88e-12 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 67.08 E-value: 1.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 4 KIAVSNLSKRF--GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVG 78
Cdd:COG4618 330 RLSVENLTVVPpgSKRPILRGVSFSLEPGeVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSqwDREELGRHIG 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 79 YLPQDFSMYP-----NmtvykamdyLAVLSDIPlrkRRKII--AKL-------LSkvnLTN-YQNMkV----KSLSGGMN 139
Cdd:COG4618 410 YLPQDVELFDgtiaeN---------IARFGDAD---PEKVVaaAKLagvhemiLR---LPDgYDTR-IgeggARLSGGQR 473
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 140 RRLGIAQALIHNPRVLIVDEPTAGLDPE-ErirfRNLLCEIANDR----IVILSTHIVGdIEATCENVAILDSGKVIYNG 214
Cdd:COG4618 474 QRIGLARALYGDPRLVVLDEPNSNLDDEgE----AALAAAIRALKargaTVVVITHRPS-LLAAVDKLLVLRDGRVQAFG 548
|
250
....*....|
gi 544973757 215 ST-EALAKLA 223
Cdd:COG4618 549 PRdEVLARLA 558
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
2-211 |
2.41e-12 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 66.74 E-value: 2.41e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 2 EMKiavsNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLL--SKTEGSIHMCGVPIE----NTKEIR 74
Cdd:NF040905 3 EMR----GITKTFPGVKALDDVNLSVREGeIHALCGENGAGKSTLMKVLSGVYphGSYEGEILFDGEVCRfkdiRDSEAL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 75 NMVgYLPQDFSMYPnmtvykamdYLAVLSDIPL---RKRRKII---------AKLLSKVNLTNYQNMKVKSLSGGMNRRL 142
Cdd:NF040905 79 GIV-IIHQELALIP---------YLSIAENIFLgneRAKRGVIdwnetnrraRELLAKVGLDESPDTLVTDIGVGKQQLV 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 143 GIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIV-ILSTHIVGDIEATCENVAILDSGKVI 211
Cdd:NF040905 149 EIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITsIIISHKLNEIRRVADSITVLRDGRTI 218
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
15-220 |
2.70e-12 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 66.91 E-value: 2.70e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 15 GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGYLPQDFSMY---- 87
Cdd:PRK13657 346 NSRQGVEDVSFEAKPGqTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRtvTRASLRRNIAVVFQDAGLFnrsi 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 88 --------PNMT---VYKAMDyLAVLSDIPLRKRRKiiakllskvnltnYQNM---KVKSLSGGMNRRLGIAQALIHNPR 153
Cdd:PRK13657 426 ednirvgrPDATdeeMRAAAE-RAQAHDFIERKPDG-------------YDTVvgeRGRQLSGGERQRLAIARALLKDPP 491
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 154 VLIVDEPTAGLDPEERIRFRNLLCEIANDRivilSTHIVGDIEATCEN---VAILDSGKVIYNGSTEALA 220
Cdd:PRK13657 492 ILILDEATSALDVETEAKVKAALDELMKGR----TTFIIAHRLSTVRNadrILVFDNGRVVESGSFDELV 557
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
2-165 |
9.16e-12 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 65.02 E-value: 9.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 2 EMKIAVSNLSKrfgkkQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE---IRNMV 77
Cdd:PRK10762 255 EVRLKVDNLSG-----PGVNDVSFTLRKGeILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPqdgLANGI 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 GYLPQD---------FSMYPNMTVyKAMDYLAVLSdIPLRKRRKIIA--KLLSKVNL-TNYQNMKVKSLSGGMNRRLGIA 145
Cdd:PRK10762 330 VYISEDrkrdglvlgMSVKENMSL-TALRYFSRAG-GSLKHADEQQAvsDFIRLFNIkTPSMEQAIGLLSGGNQQKVAIA 407
|
170 180
....*....|....*....|
gi 544973757 146 QALIHNPRVLIVDEPTAGLD 165
Cdd:PRK10762 408 RGLMTRPKVLILDEPTRGVD 427
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
33-206 |
1.11e-11 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 64.83 E-value: 1.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 33 GLLGRNGAGKTTFMRILATLL------SKTEGSI-----HMCGVPIEN------TKEIRnmVGYLPQDFSMYPNmtVYKA 95
Cdd:PRK13409 103 GILGPNGIGKTTAVKILSGELipnlgdYEEEPSWdevlkRFRGTELQNyfkklyNGEIK--VVHKPQYVDLIPK--VFKG 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 96 MdylavLSDIpLRK--RRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFR 173
Cdd:PRK13409 179 K-----VREL-LKKvdERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDIRQRLNVA 252
|
170 180 190
....*....|....*....|....*....|...
gi 544973757 174 NLLCEIANDRIVILSTHivgDIeatcenvAILD 206
Cdd:PRK13409 253 RLIRELAEGKYVLVVEH---DL-------AVLD 275
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
7-165 |
1.51e-11 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 64.28 E-value: 1.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLS-KRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN--TKEIRNM-VGYLP 81
Cdd:COG3845 260 VENLSvRDDRGVPALKDVSLEVRAGeILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGlsPRERRRLgVAYIP 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 QD---FSMYPNMTVYKAMdylaVLSDI---PLRKR------------RKIIAKLlsKVNLTNyQNMKVKSLSGGMNRRLG 143
Cdd:COG3845 340 EDrlgRGLVPDMSVAENL----ILGRYrrpPFSRGgfldrkairafaEELIEEF--DVRTPG-PDTPARSLSGGNQQKVI 412
|
170 180
....*....|....*....|..
gi 544973757 144 IAQALIHNPRVLIVDEPTAGLD 165
Cdd:COG3845 413 LARELSRDPKLLIAAQPTRGLD 434
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
2-190 |
1.54e-11 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 63.26 E-value: 1.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 2 EMKIAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATL-----LSKTEGSIHMCGVPIENTK---- 71
Cdd:PRK14243 8 ETVLRTENLNVYYGSFLAVKNVWLDIPKNqITAFIGPSGCGKSTILRCFNRLndlipGFRVEGKVTFHGKNLYAPDvdpv 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 72 EIRNMVGYL---PQDF--SMYPNMTV------YKA-MDYLAVLSdipLRKrrkiiAKLLSKVNltNYQNMKVKSLSGGMN 139
Cdd:PRK14243 88 EVRRRIGMVfqkPNPFpkSIYDNIAYgaringYKGdMDELVERS---LRQ-----AALWDEVK--DKLKQSGLSLSGGQQ 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 544973757 140 RRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILSTH 190
Cdd:PRK14243 158 QRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQYTIIIVTH 208
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
5-211 |
1.92e-11 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 64.20 E-value: 1.92e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILAtllskteGSIHMCGVPIENTKEIRnmVGYLPQD 83
Cdd:PRK11147 4 ISIHGAWLSFSDAPLLDNAELHIEDNeRVCLVGRNGAGKSTLMKILN-------GEVLLDDGRIIYEQDLI--VARLQQD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTVYkamDYLA-------------------VLSDiPLRKRRKIIAKLLSKVNLTN-YQ---------------- 127
Cdd:PRK11147 75 PPRNVEGTVY---DFVAegieeqaeylkryhdishlVETD-PSEKNLNELAKLQEQLDHHNlWQlenrinevlaqlgldp 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 128 NMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE-----ERI--RFRNLLCEIANDRIVI--LSTHIVGdieat 198
Cdd:PRK11147 151 DAALSSLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDIEtiewlEGFlkTFQGSIIFISHDRSFIrnMATRIVD----- 225
|
250
....*....|...
gi 544973757 199 cenvaiLDSGKVI 211
Cdd:PRK11147 226 ------LDRGKLV 232
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
17-221 |
1.95e-11 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 64.10 E-value: 1.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 17 KQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILATLLsKTEGSIHMCGVPIE--NTKEIRNMVGYLPQDfSMYPNMTVy 93
Cdd:PRK11174 363 KTLAGPLNFTLPAGQRiALVGPSGAGKTSLLNALLGFL-PYQGSLKINGIELRelDPESWRKHLSWVGQN-PQLPHGTL- 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 94 kaMDYLAvLSDIPLRKRRkiIAKLLSKVNLTNYQNMKVK-----------SLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:PRK11174 440 --RDNVL-LGNPDASDEQ--LQQALENAWVSEFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQLLLLDEPTA 514
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544973757 163 GLD--PEERIrfRNLLCEIANDRIVILSTHIVGDIEAtCENVAILDSGKVIYNGSTEALAK 221
Cdd:PRK11174 515 SLDahSEQLV--MQALNAASRRQTTLMVTHQLEDLAQ-WDQIWVMQDGQIVQQGDYAELSQ 572
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
9-167 |
2.30e-11 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 61.90 E-value: 2.30e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 9 NLSKRFGKKQALDNINLEIDSGMFGLL-GRNGAGKTTFMRILATLLSKTEGSIhmcgvpientkEIRNMVGYLPQDFSM- 86
Cdd:COG2401 35 GVELRVVERYVLRDLNLEIEPGEIVLIvGASGSGKSTLLRLLAGALKGTPVAG-----------CVDVPDNQFGREASLi 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 87 ---YPNMTVYKAMDYLAV--LSDIPLRKRRkiiakllskvnltnyqnmkVKSLSGGMNRRLGIAQALIHNPRVLIVDEPT 161
Cdd:COG2401 104 daiGRKGDFKDAVELLNAvgLSDAVLWLRR-------------------FKELSTGQKFRFRLALLLAERPKLLVIDEFC 164
|
....*.
gi 544973757 162 AGLDPE 167
Cdd:COG2401 165 SHLDRQ 170
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
6-216 |
2.31e-11 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 62.64 E-value: 2.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 6 AVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHM---CGVPIE----NTKEIRNMV 77
Cdd:PRK11701 8 SVRGLTKLYGPRKGCRDVSFDLYPGeVLGIVGESGSGKTTLLNALSARLAPDAGEVHYrmrDGQLRDlyalSEAERRRLL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 78 ----GYLPQDFSMYPNMTVYKAMDYLAVLSDIPLR---KRRKIIAKLLSKVNL-TNYQNMKVKSLSGGMNRRLGIAQALI 149
Cdd:PRK11701 88 rtewGFVHQHPRDGLRMQVSAGGNIGERLMAVGARhygDIRATAGDWLERVEIdAARIDDLPTTFSGGMQQRLQIARNLV 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 150 HNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDR--IVILSTHIVGDIEATCENVAILDSGKVIYNGST 216
Cdd:PRK11701 168 THPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELglAVVIVTHDLAVARLLAHRLLVMKQGRVVESGLT 236
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
34-238 |
2.48e-11 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 62.26 E-value: 2.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 34 LLGRNGAGKTTFMRILATLLSkTEGSIHMCGVPIE--NTKEIRNMVGYLPQDFSMYPNMTVYKamdYLAV-LSD-IPLRK 109
Cdd:PRK03695 27 LVGPNGAGKSTLLARMAGLLP-GSGSIQFAGQPLEawSAAELARHRAYLSQQQTPPFAMPVFQ---YLTLhQPDkTRTEA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 110 RRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQAL--IH---NP--RVLIVDEPTAGLDPEERIRFRNLLCEIAND 182
Cdd:PRK03695 103 VASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVlqVWpdiNPagQLLLLDEPMNSLDVAQQAALDRLLSELCQQ 182
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544973757 183 RI-VILSTHivgDIEATCEN---VAILDSGKVIYNGST-EALAKLAEGKVYSIEVDKKDIE 238
Cdd:PRK03695 183 GIaVVMSSH---DLNHTLRHadrVWLLKQGKLLASGRRdEVLTPENLAQVFGVNFRRLDVE 240
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
9-167 |
3.21e-11 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 63.60 E-value: 3.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 9 NLSKRFG-KKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILAtllsktegsihmcGVPIENTKEIRNM----VGYLPQ 82
Cdd:PRK11819 11 RVSKVVPpKKQILKDISLSFFPGAkIGVLGLNGAGKSTLLRIMA-------------GVDKEFEGEARPApgikVGYLPQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 DFSMYPNMTVY--------KAMDYLAVLSDI------PLRKRRKII---AKLLSKVNLTNYQNM---------------- 129
Cdd:PRK11819 78 EPQLDPEKTVRenveegvaEVKAALDRFNEIyaayaePDADFDALAaeqGELQEIIDAADAWDLdsqleiamdalrcppw 157
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 544973757 130 --KVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE 167
Cdd:PRK11819 158 daKVTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAE 197
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
7-221 |
5.12e-11 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 62.07 E-value: 5.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKK----QALDNINLEIDSG-MFGLLGRNGAGKT----TFM-------RILATLLSKTEGSIHMCgvpieNT 70
Cdd:PRK11022 6 VDKLSVHFGDEsapfRAVDRISYSVKQGeVVGIVGESGSGKSvsslAIMglidypgRVMAEKLEFNGQDLQRI-----SE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 71 KEIRNMVG----YLPQD--FSMYPNMTV-YKAMDYLAVLSDIPLRKRRKIIAKLLSKVN-------LTNYQNmkvkSLSG 136
Cdd:PRK11022 81 KERRNLVGaevaMIFQDpmTSLNPCYTVgFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGipdpasrLDVYPH----QLSG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 137 GMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAN--DRIVILSTHIVGDIEATCENVAILDSGKVIYNG 214
Cdd:PRK11022 157 GMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQkeNMALVLITHDLALVAEAAHKIIVMYAGQVVETG 236
|
....*..
gi 544973757 215 STEALAK 221
Cdd:PRK11022 237 KAHDIFR 243
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
7-228 |
5.68e-11 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 60.62 E-value: 5.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLLSK--TEGSIHMCGvpientKEIRNMvgyLPQD 83
Cdd:cd03217 3 IKDLHVSVGGKEILKGVNLTIKKGEvHALMGPNGSGKSTLAKTIMGHPKYevTEGEILFKG------EDITDL---PPEE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSmypNMTVYKAMDYLAvlsDIPLRKrrkiIAKLLSKVNltnyqnmkvKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:cd03217 74 RA---RLGIFLAFQYPP---EIPGVK----NADFLRYVN---------EGFSGGEKKRNEILQLLLLEPDLAILDEPDSG 134
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544973757 164 LDpeerIRFRNLLCEIAN-----DRIVILSTH---IVGDIEATceNVAILDSGKVIYNGSTEaLAKLAEGKVY 228
Cdd:cd03217 135 LD----IDALRLVAEVINklreeGKSVLIITHyqrLLDYIKPD--RVHVLYDGRIVKSGDKE-LALEIEKKGY 200
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
7-217 |
5.85e-11 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 62.05 E-value: 5.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRF----GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSK---TEGSIHMCGVPIENTKE-----I 73
Cdd:PRK09473 15 VKDLRVTFstpdGDVTAVNDLNFSLRAGeTLGIVGESGSGKSQTAFALMGLLAAngrIGGSATFNGREILNLPEkelnkL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 74 R-NMVGYLPQD--FSMYPNMTVYKAMdyLAVLSdipLRKR-RKIIA-----KLLSKVNLTNYQ---NMKVKSLSGGMNRR 141
Cdd:PRK09473 95 RaEQISMIFQDpmTSLNPYMRVGEQL--MEVLM---LHKGmSKAEAfeesvRMLDAVKMPEARkrmKMYPHEFSGGMRQR 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 544973757 142 LGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAND--RIVILSTHIVGDIEATCENVAILDSGKVIYNGSTE 217
Cdd:PRK09473 170 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfnTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNAR 247
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
4-228 |
6.76e-11 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 62.43 E-value: 6.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 4 KIAVSNLSKRFGK-KQALDNINLEIDS-GMFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE--NTKEIRNMVGY 79
Cdd:PRK10790 340 RIDIDNVSFAYRDdNLVLQNINLSVPSrGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSslSHSVLRQGVAM 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 80 LPQD-----FSMYPNMTVYKAMDYLAVLsdiplrkrrkiiaKLLSKVNLTNYqnmkVKSLSGGMNRRLG----------- 143
Cdd:PRK10790 420 VQQDpvvlaDTFLANVTLGRDISEEQVW-------------QALETVQLAEL----ARSLPDGLYTPLGeqgnnlsvgqk 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 144 ----IAQALIHNPRVLIVDEPTAGLDP--EERI-------RFRNLLCEIANDriviLSThIVgdiEAtcENVAILDSGKV 210
Cdd:PRK10790 483 qllaLARVLVQTPQILILDEATANIDSgtEQAIqqalaavREHTTLVVIAHR----LST-IV---EA--DTILVLHRGQA 552
|
250
....*....|....*...
gi 544973757 211 IYNGSTEALAKlAEGKVY 228
Cdd:PRK10790 553 VEQGTHQQLLA-AQGRYW 569
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
18-176 |
9.52e-11 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 61.52 E-value: 9.52e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 18 QALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGV-----PIENTKEIRNMVGYLPQD--FSMYPN 89
Cdd:PRK11308 29 KALDGVSFTLERGkTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQdllkaDPEAQKLLRQKIQIVFQNpyGSLNPR 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 90 MTVYKAMDY-LAVLSDIPLRKRRKIIAKLLSKVNL-----TNYQNMkvksLSGGMNRRLGIAQALIHNPRVLIVDEPTAG 163
Cdd:PRK11308 109 KKVGQILEEpLLINTSLSAAERREKALAMMAKVGLrpehyDRYPHM----FSGGQRQRIAIARALMLDPDVVVADEPVSA 184
|
170
....*....|...
gi 544973757 164 LDPEERIRFRNLL 176
Cdd:PRK11308 185 LDVSVQAQVLNLM 197
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
10-189 |
1.77e-10 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 61.34 E-value: 1.77e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 10 LSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMcgvpienTKEIRnmVGYLPQdfsmyp 88
Cdd:PRK10636 318 VSAGYGDRIILDSIKLNLVPGsRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL-------AKGIK--LGYFAQ------ 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 89 nmtvyKAMDYLAVlSDIPLRKRRKIIAKLLSKvNLTNY------QNMKV----KSLSGGMNRRLGIAQALIHNPRVLIVD 158
Cdd:PRK10636 383 -----HQLEFLRA-DESPLQHLARLAPQELEQ-KLRDYlggfgfQGDKVteetRRFSGGEKARLVLALIVWQRPNLLLLD 455
|
170 180 190
....*....|....*....|....*....|....*...
gi 544973757 159 EPTAGLDPEER-------IRFRNLLCEIANDRIVILST 189
Cdd:PRK10636 456 EPTNHLDLDMRqaltealIDFEGALVVVSHDRHLLRST 493
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
134-219 |
2.08e-10 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 59.71 E-value: 2.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 134 LSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRI--VILSTHIVGDIEATCENVAILDSGKVI 211
Cdd:PRK10418 141 MSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVAQARILDLLESIVQKRAlgMLLVTHDMGVVARLADDVAVMSHGRIV 220
|
....*...
gi 544973757 212 YNGSTEAL 219
Cdd:PRK10418 221 EQGDVETL 228
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
10-219 |
2.95e-10 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 60.49 E-value: 2.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 10 LSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSkTEGSIHMCGVPIENTKE-----IRNMVGYLPQD 83
Cdd:PRK15134 292 LKRTVDHNVVVKNISFTLRPGeTLGLVGESGSGKSTTGLALLRLIN-SQGEIWFDGQPLHNLNRrqllpVRHRIQVVFQD 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 fsmyPNMTVYKAMDYLAVLSD--------IPLRKRRKIIAKLLSKVNLTNYQNMKVKS-LSGGMNRRLGIAQALIHNPRV 154
Cdd:PRK15134 371 ----PNSSLNPRLNVLQIIEEglrvhqptLSAAQREQQVIAVMEEVGLDPETRHRYPAeFSGGQRQRIAIARALILKPSL 446
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 155 LIVDEPTAGLDPEERIRFRNLLCEIANDRIV--ILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK15134 447 IILDEPTSSLDKTVQAQILALLKSLQQKHQLayLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERV 513
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
20-215 |
3.95e-10 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 59.07 E-value: 3.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 20 LDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLS--------KTEGSIHMCGVPIENTKEIR--NMVGYLPQD----- 83
Cdd:PRK13547 17 LRDLSLRIEPGrVTALLGRNGAGKSTLLKALAGDLTgggaprgaRVTGDVTLNGEPLAAIDAPRlaRLRAVLPQAaqpaf 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 -FSmypnmtvykaMDYLAVLSDIPLRKR--------RKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQAL------ 148
Cdd:PRK13547 97 aFS----------AREIVLLGRYPHARRagalthrdGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLaqlwpp 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 544973757 149 ---IHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAND-RIVILSthIVGDIEAT---CENVAILDSGKVIYNGS 215
Cdd:PRK13547 167 hdaAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDwNLGVLA--IVHDPNLAarhADRIAMLADGAIVAHGA 238
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
22-187 |
4.87e-10 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 59.68 E-value: 4.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 22 NINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK-EIRNMVG--YLPQD---------FSMYP 88
Cdd:PRK15439 281 NISLEVRAGeILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALStAQRLARGlvYLPEDrqssglyldAPLAW 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 89 NMT--VYKAMDYL-------AVLSdiplRKRRKIIAKLlskvnltNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDE 159
Cdd:PRK15439 361 NVCalTHNRRGFWikparenAVLE----RYRRALNIKF-------NHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDE 429
|
170 180
....*....|....*....|....*...
gi 544973757 160 PTAGLDPEERIRFRNLLCEIANDRIVIL 187
Cdd:PRK15439 430 PTRGVDVSARNDIYQLIRSIAAQNVAVL 457
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
15-165 |
5.08e-10 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 60.12 E-value: 5.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 15 GKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSK---TEGSIHMCGVPIENTKEIRnmVGYLPQDFSMYPNM 90
Cdd:TIGR00956 774 EKRVILNNVDGWVKPGtLTALMGASGAGKTTLLNVLAERVTTgviTGGDRLVNGRPLDSSFQRS--IGYVQQQDLHLPTS 851
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 91 TVYKAMDYLAVL---SDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMN----RRLGIAQALIHNPRVLI-VDEPTA 162
Cdd:TIGR00956 852 TVRESLRFSAYLrqpKSVSKSEKMEYVEEVIKLLEMESYADAVVGVPGEGLNveqrKRLTIGVELVAKPKLLLfLDEPTS 931
|
...
gi 544973757 163 GLD 165
Cdd:TIGR00956 932 GLD 934
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
33-206 |
5.90e-10 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 59.80 E-value: 5.90e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 33 GLLGRNGAGKTTFMRILATLLS------KTEGSI-----HMCGVPIEN------TKEIRnmVGYLPQdfsmYpnmtVYKA 95
Cdd:COG1245 103 GILGPNGIGKSTALKILSGELKpnlgdyDEEPSWdevlkRFRGTELQDyfkklaNGEIK--VAHKPQ----Y----VDLI 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 96 MDYL-AVLSDIpLRK--RRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRF 172
Cdd:COG1245 173 PKVFkGTVREL-LEKvdERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIYQRLNV 251
|
170 180 190
....*....|....*....|....*....|....*
gi 544973757 173 RNLLCEIAN-DRIVILSTHivgDIeatcenvAILD 206
Cdd:COG1245 252 ARLIRELAEeGKYVLVVEH---DL-------AILD 276
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
16-187 |
1.06e-09 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 58.68 E-value: 1.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 16 KKQALDNINLEIDSG-MFGLLGRNGAGKTTFMR-ILATLLSKTEGSIHMCGVPIEN---TKEIRNMVGYLPQD---FSMY 87
Cdd:TIGR02633 272 HRKRVDDVSFSLRRGeILGVAGLVGAGRTELVQaLFGAYPGKFEGNVFINGKPVDIrnpAQAIRAGIAMVPEDrkrHGIV 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 88 PNMTVYK-----AMDYLAVLSDIPLRKRRKIIAKLLSKVNL-TNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPT 161
Cdd:TIGR02633 352 PILGVGKnitlsVLKSFCFKMRIDAAAELQIIGSAIQRLKVkTASPFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEPT 431
|
170 180
....*....|....*....|....*.
gi 544973757 162 AGLDPEERIRFRNLLCEIANDRIVIL 187
Cdd:TIGR02633 432 RGVDVGAKYEIYKLINQLAQEGVAII 457
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
55-196 |
1.27e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 58.89 E-value: 1.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 55 KTEGSIHMCGVPI--ENTKEIRNMVGYLPQDfSMYPNMTVYKAMDY---LAVLSDIPLRKRRKIIAKLLSkvNLTNYQNM 129
Cdd:PTZ00265 1274 KNSGKILLDGVDIcdYNLKDLRNLFSIVSQE-PMLFNMSIYENIKFgkeDATREDVKRACKFAAIDEFIE--SLPNKYDT 1350
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 544973757 130 KV----KSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAN--DRIVILSTHIVGDIE 196
Cdd:PTZ00265 1351 NVgpygKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDkaDKTIITIAHRIASIK 1423
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
5-165 |
3.35e-09 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 57.49 E-value: 3.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLLSKTEGSIHMCG---------------VP-- 66
Cdd:PRK10636 2 IVFSSLQIRRGVRVLLDNATATINPGQkVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGnwqlawvnqetpalpQPal 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 67 ---IENTKEIRNMVGYLPQDFSM---YPNMTVYKAMDYLAVLSdipLRKRrkiIAKLLSKVNLTNYQNMK-VKSLSGGMN 139
Cdd:PRK10636 82 eyvIDGDREYRQLEAQLHDANERndgHAIATIHGKLDAIDAWT---IRSR---AASLLHGLGFSNEQLERpVSDFSGGWR 155
|
170 180
....*....|....*....|....*.
gi 544973757 140 RRLGIAQALIHNPRVLIVDEPTAGLD 165
Cdd:PRK10636 156 MRLNLAQALICRSDLLLLDEPTNHLD 181
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
5-167 |
3.88e-09 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 57.05 E-value: 3.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEI-DSGMFGLLGRNGAGKTTFMRILATLLSKTEGSIHmcgvpIENTKEIrnmvGYLPQ- 82
Cdd:PRK11819 325 IEAENLSKSFGDRLLIDDLSFSLpPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIK-----IGETVKL----AYVDQs 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 -DfSMYPNMTVYKAM----DYLAVLS-DIPLRkrrkiiaKLLSKVNLT-NYQNMKVKSLSGGMNRRLGIAQALIHNPRVL 155
Cdd:PRK11819 396 rD-ALDPNKTVWEEIsgglDIIKVGNrEIPSR-------AYVGRFNFKgGDQQKKVGVLSGGERNRLHLAKTLKQGGNVL 467
|
170
....*....|..
gi 544973757 156 IVDEPTAGLDPE 167
Cdd:PRK11819 468 LLDEPTNDLDVE 479
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
21-165 |
4.18e-09 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 56.86 E-value: 4.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 21 DNINLEIDSG-MFGLLGRNGAGKT-TFMRILATLLSKTEGSIHMCGVP--IENTKE-IRNMVGYLPQD---FSMYPNMTV 92
Cdd:PRK13549 279 DDVSFSLRRGeILGIAGLVGAGRTeLVQCLFGAYPGRWEGEIFIDGKPvkIRNPQQaIAQGIAMVPEDrkrDGIVPVMGV 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 93 YKAMDyLAVLSDIPLRKR----------RKIIAKLLSKvnlTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:PRK13549 359 GKNIT-LAALDRFTGGSRiddaaelktiLESIQRLKVK---TASPELAIARLSGGNQQKAVLAKCLLLNPKILILDEPTR 434
|
...
gi 544973757 163 GLD 165
Cdd:PRK13549 435 GID 437
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
7-167 |
5.71e-09 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 56.50 E-value: 5.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHmCGVPIEntkeirnmVGYlpqdFS 85
Cdd:PRK11147 322 MENVNYQIDGKQLVKDFSAQVQRGdKIALIGPNGCGKTTLLKLMLGQLQADSGRIH-CGTKLE--------VAY----FD 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 86 MY-----PNMTVykaMDYLA--------------VLSDI------PLRKRrkiiakllskvnltnyqnMKVKSLSGGMNR 140
Cdd:PRK11147 389 QHraeldPEKTV---MDNLAegkqevmvngrprhVLGYLqdflfhPKRAM------------------TPVKALSGGERN 447
|
170 180
....*....|....*....|....*..
gi 544973757 141 RLGIAQALIHNPRVLIVDEPTAGLDPE 167
Cdd:PRK11147 448 RLLLARLFLKPSNLLILDEPTNDLDVE 474
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
5-214 |
5.71e-09 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 56.44 E-value: 5.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMcgvpienTKEIRnmVGYLPQD 83
Cdd:PRK15064 2 LSTANITMQFGAKPLFENISVKFGGGnRYGLIGANGCGKSTFMKILGGDLEPSAGNVSL-------DPNER--LGKLRQD 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 FSMYPNMTV-----------YKAM---------------DYLAVlSDIPLR---------KRRKiiAKLLSKVNL-TNYQ 127
Cdd:PRK15064 73 QFAFEEFTVldtvimghtelWEVKqerdriyalpemseeDGMKV-ADLEVKfaemdgytaEARA--GELLLGVGIpEEQH 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 128 NMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEErIRFrnlLCEIANDR---IVILStHIVGDIEATCENVAI 204
Cdd:PRK15064 150 YGLMSEVAPGWKLRVLLAQALFSNPDILLLDEPTNNLDINT-IRW---LEDVLNERnstMIIIS-HDRHFLNSVCTHMAD 224
|
250
....*....|.
gi 544973757 205 LDSGKV-IYNG 214
Cdd:PRK15064 225 LDYGELrVYPG 235
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
7-224 |
1.30e-08 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 54.30 E-value: 1.30e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMRILA-----TLlskTEGSIHMCGvpientKEIRNM---- 76
Cdd:COG0396 3 IKNLHVSVEGKEILKGVNLTIKPGEVhAIMGPNGSGKSTLAKVLMghpkyEV---TSGSILLDG------EDILELspde 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 77 -----VGYL---PQDFsmyPNMTVykaMDYL--AV----LSDIPLRKRRKIIAKLLSKVNLTN-----YQNmkvKSLSGG 137
Cdd:COG0396 74 raragIFLAfqyPVEI---PGVSV---SNFLrtALnarrGEELSAREFLKLLKEKMKELGLDEdfldrYVN---EGFSGG 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 138 MNRRLGIAQALIHNPRVLIVDEPTAGLDpeerIRFRNLLCEIAN-----DRIVILSTH---IVGDIEATceNVAILDSGK 209
Cdd:COG0396 145 EKKRNEILQMLLLEPKLAILDETDSGLD----IDALRIVAEGVNklrspDRGILIITHyqrILDYIKPD--FVHVLVDGR 218
|
250
....*....|....*
gi 544973757 210 VIYNGSTEALAKLAE 224
Cdd:COG0396 219 IVKSGGKELALELEE 233
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
7-229 |
1.81e-08 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 53.88 E-value: 1.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILA--TLLSKTEGSIHMCGVPI-ENTKEIRNMVG-YLP 81
Cdd:CHL00131 10 IKNLHASVNENEILKGLNLSINKGeIHAIMGPNGSGKSTLSKVIAghPAYKILEGDILFKGESIlDLEPEERAHLGiFLA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 ------------QDFSmypnMTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVN-----LTNYQNmkvKSLSGGMNRRLGI 144
Cdd:CHL00131 90 fqypieipgvsnADFL----RLAYNSKRKFQGLPELDPLEFLEIINEKLKLVGmdpsfLSRNVN---EGFSGGEKKRNEI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 145 AQALIHNPRVLIVDEPTAGLDPEErirfrnlLCEIAN--------DRIVILSTH-------IVGDIeatcenVAILDSGK 209
Cdd:CHL00131 163 LQMALLDSELAILDETDSGLDIDA-------LKIIAEginklmtsENSIILITHyqrlldyIKPDY------VHVMQNGK 229
|
250 260
....*....|....*....|
gi 544973757 210 VIYNGSTEaLAKLAEGKVYS 229
Cdd:CHL00131 230 IIKTGDAE-LAKELEKKGYD 248
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
36-190 |
3.81e-08 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 52.57 E-value: 3.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 36 GRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKeiRNMVGYLPQDFSMYPNMTVYKAMDYLAVLSDiplrkRRKIIA 115
Cdd:PRK13541 33 GANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIA--KPYCTYIGHNLGLKLEMTVFENLKFWSEIYN-----SAETLY 105
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 116 KLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAND-RIVILSTH 190
Cdd:PRK13541 106 AAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLNNLIVMKANSgGIVLLSSH 181
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
20-233 |
5.57e-08 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 53.80 E-value: 5.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 20 LDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENT--KEIRNMVGYLPQD------------- 83
Cdd:TIGR00957 1302 LRHINVTIHGGeKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIglHDLRFKITIIPQDpvlfsgslrmnld 1381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 84 -FSMYPNMTVYKAMDyLAVLSDIplrkrrkiIAKLLSKVNLTNYQNMKvkSLSGGMNRRLGIAQALIHNPRVLIVDEPTA 162
Cdd:TIGR00957 1382 pFSQYSDEEVWWALE-LAHLKTF--------VSALPDKLDHECAEGGE--NLSVGQRQLVCLARALLRKTKILVLDEATA 1450
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 544973757 163 GLDPEERIRFRNLLCEIANDRIVILSTHIVGDIeATCENVAILDSGKVIYNGSTEALAKlAEGKVYSIEVD 233
Cdd:TIGR00957 1451 AVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTI-MDYTRVIVLDKGEVAEFGAPSNLLQ-QRGIFYSMAKD 1519
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
13-169 |
7.94e-08 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 53.09 E-value: 7.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 13 RFGKKQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILA-----------TLLSKTEGSihmcGvpiENTKEIRNMVGYL 80
Cdd:PRK10938 269 SYNDRPILHNLSWQVNPGEhWQIVGPNGAGKSTLLSLITgdhpqgysndlTLFGRRRGS----G---ETIWDIKKHIGYV 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 81 PQDFSM----------------YPNMTVYKAmdylavLSDiplrKRRKIIAKLLSKVNLTNYQ-NMKVKSLSGGMNRRLG 143
Cdd:PRK10938 342 SSSLHLdyrvstsvrnvilsgfFDSIGIYQA------VSD----RQQKLAQQWLDILGIDKRTaDAPFHSLSWGQQRLAL 411
|
170 180
....*....|....*....|....*.
gi 544973757 144 IAQALIHNPRVLIVDEPTAGLDPEER 169
Cdd:PRK10938 412 IVRALVKHPTLLILDEPLQGLDPLNR 437
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
5-219 |
8.04e-08 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 53.17 E-value: 8.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGK----KQALDNINLEIDSG-MFGLLGRNGAGKT----TFMRILAT-LLSKTEGSIHMCGVPIENTKE-- 72
Cdd:PRK15134 6 LAIENLSVAFRQqqtvRTVVNDVSLQIEAGeTLALVGESGSGKSvtalSILRLLPSpPVVYPSGDIRFHGESLLHASEqt 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 73 ---IR-NMVGYLPQD--FSMYPNMTVYKAMdyLAVLS-DIPLRKR--RKIIAKLLSKVN-------LTNYQNmkvkSLSG 136
Cdd:PRK15134 86 lrgVRgNKIAMIFQEpmVSLNPLHTLEKQL--YEVLSlHRGMRREaaRGEILNCLDRVGirqaakrLTDYPH----QLSG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 137 GMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAN--DRIVILSTHIVGDIEATCENVAILDSGKVIYNG 214
Cdd:PRK15134 160 GERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQelNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQN 239
|
....*
gi 544973757 215 STEAL 219
Cdd:PRK15134 240 RAATL 244
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
7-165 |
9.12e-08 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 51.49 E-value: 9.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK-EIRNMVGYLPQDF 84
Cdd:PRK13540 4 VIELDFDYHDQPLLQQISFHLPAGgLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKDLcTYQKQLCFVGHRS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 85 SMYPNMTVYKAMDYlavlsDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGL 164
Cdd:PRK13540 84 GINPYLTLRENCLY-----DIHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVAL 158
|
.
gi 544973757 165 D 165
Cdd:PRK13540 159 D 159
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
19-159 |
1.41e-07 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 52.20 E-value: 1.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 19 ALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIhmcgvpientkEIRNMVGYLPQDFSMYPNMTVYKAMD 97
Cdd:PRK13545 39 ALNNISFEVPEGeIVGIIGLNGSGKSTLSNLIAGVTMPNKGTV-----------DIKGSAALIAISSGLNGQLTGIENIE 107
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 98 YLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDE 159
Cdd:PRK13545 108 LKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDE 169
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
7-210 |
2.06e-07 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 51.71 E-value: 2.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 7 VSNLSKRFGKKqaLDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTKE---IRNMVGYLPQ 82
Cdd:PRK09700 268 VRNVTSRDRKK--VRDISFSVCRGeILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPldaVKKGMAYITE 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 83 ---------DFSMYPNMTVYKAMD---YLAVLSDIPLRKRRKIIAKLLSKVNLTNYQ-NMKVKSLSGGMNRRLGIAQALI 149
Cdd:PRK09700 346 srrdngffpNFSIAQNMAISRSLKdggYKGAMGLFHEVDEQRTAENQRELLALKCHSvNQNITELSGGNQQKVLISKWLC 425
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 150 HNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVILS-THIVGDIEATCENVAILDSGKV 210
Cdd:PRK09700 426 CCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMvSSELPEIITVCDRIAVFCEGRL 487
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
17-220 |
5.01e-07 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 50.87 E-value: 5.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 17 KQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENTK--EIRN---MVGYLPQDFS----- 85
Cdd:PRK10789 328 HPALENVNFTLKPGqMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQldSWRSrlaVVSQTPFLFSdtvan 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 86 ----MYPNMT---VYKAMDYLAVLSDIpLRkrrkiiaklLSKVNLTNYQNMKVKsLSGGMNRRLGIAQALIHNPRVLIVD 158
Cdd:PRK10789 408 nialGRPDATqqeIEHVARLASVHDDI-LR---------LPQGYDTEVGERGVM-LSGGQKQRISIARALLLNAEILILD 476
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 544973757 159 EPTAGLD--PEERIrFRNLLcEIANDRIVILSTHIVGDI-EATceNVAILDSGKVIYNGSTEALA 220
Cdd:PRK10789 477 DALSAVDgrTEHQI-LHNLR-QWGEGRTVIISAHRLSALtEAS--EILVMQHGHIAQRGNHDQLA 537
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
5-217 |
5.51e-07 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 50.62 E-value: 5.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 5 IAVSNLSKRFGKKQ----ALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIE---------NT 70
Cdd:PRK10261 13 LAVENLNIAFMQEQqkiaAVRNLSFSLQRGeTLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRrrsrqvielSE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 71 KEIRNMVGYLPQDFSMY---------PNMTVYKAMDYLAVLSDIPLRKRRKIIAK-LLSKVNLTNYQNMKVK---SLSGG 137
Cdd:PRK10261 93 QSAAQMRHVRGADMAMIfqepmtslnPVFTVGEQIAESIRLHQGASREEAMVEAKrMLDQVRIPEAQTILSRyphQLSGG 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 138 MNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRI--VILSTHIVGDIEATCENVAILDSGKVIYNGS 215
Cdd:PRK10261 173 MRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSmgVIFITHDMGVVAEIADRVLVMYQGEAVETGS 252
|
..
gi 544973757 216 TE 217
Cdd:PRK10261 253 VE 254
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
17-165 |
1.21e-06 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 49.97 E-value: 1.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 17 KQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSihmcgvpienTKEIRNMVGYLPQdFSMYPNMTV--- 92
Cdd:PLN03232 630 KPTLSDINLEIPVGsLVAIVGGTGEGKTSLISAMLGELSHAETS----------SVVIRGSVAYVPQ-VSWIFNATVren 698
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 93 ------------YKAMDYLAVLSDIPLRKRRkiiakllskvNLTNYQNMKVkSLSGGMNRRLGIAQALIHNPRVLIVDEP 160
Cdd:PLN03232 699 ilfgsdfeseryWRAIDVTALQHDLDLLPGR----------DLTEIGERGV-NISGGQKQRVSMARAVYSNSDIYIFDDP 767
|
....*
gi 544973757 161 TAGLD 165
Cdd:PLN03232 768 LSALD 772
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
28-206 |
1.29e-06 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 48.52 E-value: 1.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 28 DSGMFGLLGRNGAGKTTFMRILATLLSKTEGSI-----------HMCGVPIENT-KEIRN---MVGYLPQDFSMYPNMTV 92
Cdd:cd03236 25 EGQVLGLVGPNGIGKSTALKILAGKLKPNLGKFddppdwdeildEFRGSELQNYfTKLLEgdvKVIVKPQYVDLIPKAVK 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 93 YKAMDYLAVLSDiplrkrRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRF 172
Cdd:cd03236 105 GKVGELLKKKDE------RGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRLNA 178
|
170 180 190
....*....|....*....|....*....|....*
gi 544973757 173 RNLLCEIAND-RIVILSTHivgdieatceNVAILD 206
Cdd:cd03236 179 ARLIRELAEDdNYVLVVEH----------DLAVLD 203
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
32-165 |
1.55e-06 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 49.09 E-value: 1.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 32 FGLLGRNGAGKTTFMRILAtlLSKTEGSIHMCGV---------------------PIENTKEIRNMVGYLPQDFSM-YPN 89
Cdd:PLN03073 206 YGLVGRNGTGKTTFLRYMA--MHAIDGIPKNCQIlhveqevvgddttalqcvlntDIERTQLLEEEAQLVAQQRELeFET 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 90 MTVYKAMDYLAVLSDIPLRKRRKIIAKLLSKVNL-----------------TNYQNMKVKSLSGGMNRRLGIAQALIHNP 152
Cdd:PLN03073 284 ETGKGKGANKDGVDKDAVSQRLEEIYKRLELIDAytaearaasilaglsftPEMQVKATKTFSGGWRMRIALARALFIEP 363
|
170
....*....|...
gi 544973757 153 RVLIVDEPTAGLD 165
Cdd:PLN03073 364 DLLLLDEPTNHLD 376
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
114-219 |
1.59e-06 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 48.86 E-value: 1.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 114 IAKLLSKvnltnyqnmKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRI-VILSTHIV 192
Cdd:PRK10938 125 ITALLDR---------RFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLASLHQSGItLVLVLNRF 195
|
90 100
....*....|....*....|....*..
gi 544973757 193 GDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK10938 196 DEIPDFVQFAGVLADCTLAETGEREEI 222
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
19-176 |
2.41e-06 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 48.43 E-value: 2.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 19 ALDNINLEIDSG--MFgLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPI--ENTKEIRNMVGYLPQDFSMYPNMTVYK 94
Cdd:PRK10522 338 SVGPINLTIKRGelLF-LIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVtaEQPEDYRKLFSAVFTDFHLFDQLLGPE 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 95 AMDYLAVLSDIPLRKrrkiiAKLLSKVNLTNYQNMKVKsLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE-ERIRFR 173
Cdd:PRK10522 417 GKPANPALVEKWLER-----LKMAHKLELEDGRISNLK-LSKGQKKRLALLLALAEERDILLLDEWAADQDPHfRREFYQ 490
|
...
gi 544973757 174 NLL 176
Cdd:PRK10522 491 VLL 493
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
22-195 |
4.48e-06 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 48.10 E-value: 4.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 22 NINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVpiENTKEI-----RNMVGYLPQDFSMYPN------ 89
Cdd:PTZ00265 403 DLNFTLTEGkTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDS--HNLKDInlkwwRSKIGVVSQDPLLFSNsiknni 480
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 90 -MTVYKAMDyLAVLSDI----------PLRKRRKIIAKLLSKVNLT--------------NYQNMK-------------- 130
Cdd:PTZ00265 481 kYSLYSLKD-LEALSNYynedgndsqeNKNKRNSCRAKCAGDLNDMsnttdsneliemrkNYQTIKdsevvdvskkvlih 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 131 -----------------VKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIA--NDRIVILSTHI 191
Cdd:PTZ00265 560 dfvsalpdkyetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKgnENRITIIIAHR 639
|
....
gi 544973757 192 VGDI 195
Cdd:PTZ00265 640 LSTI 643
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
15-165 |
6.51e-06 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 47.43 E-value: 6.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 15 GKKQALDNINLEIDSGMF-GLLGRNGAGKTTFMR-ILATLLSKTEGSIhmcgvpientkEIRNMVGYLPQdFSMYPNMTV 92
Cdd:PLN03130 628 AERPTLSNINLDVPVGSLvAIVGSTGEGKTSLISaMLGELPPRSDASV-----------VIRGTVAYVPQ-VSWIFNATV 695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 93 ---------------YKAMDYLAVLSDIplrkrrkiiaKLLSKVNLTNYQNMKVkSLSGGMNRRLGIAQALIHNPRVLIV 157
Cdd:PLN03130 696 rdnilfgspfdperyERAIDVTALQHDL----------DLLPGGDLTEIGERGV-NISGGQKQRVSMARAVYSNSDVYIF 764
|
....*...
gi 544973757 158 DEPTAGLD 165
Cdd:PLN03130 765 DDPLSALD 772
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
10-170 |
9.94e-06 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 45.26 E-value: 9.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 10 LSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVpientkeirnMVGYLPQdfsmypn 89
Cdd:cd03222 6 CVKRYGVFFLLVELGVVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGI----------TPVYKPQ------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 90 mtvykamdylavlsdiplrkrrKIiakllskvnltnyqnmkvkSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEER 169
Cdd:cd03222 69 ----------------------YI-------------------DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQR 107
|
.
gi 544973757 170 I 170
Cdd:cd03222 108 L 108
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
19-210 |
1.12e-05 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 45.96 E-value: 1.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 19 ALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGvpientkeirnMVGYLPQDFSMYPNMTVYKAMD 97
Cdd:PRK13546 39 ALDDISLKAYEGdVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNG-----------EVSVIAISAGLSGQLTGIENIE 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 98 YLAVLSDIPLRKRRKIIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLC 177
Cdd:PRK13546 108 FKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIY 187
|
170 180 190
....*....|....*....|....*....|....
gi 544973757 178 EI-ANDRIVILSTHIVGDIEATCENVAILDSGKV 210
Cdd:PRK13546 188 EFkEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKL 221
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
2-210 |
1.53e-05 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 45.88 E-value: 1.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 2 EMKIAVSNLSKRfgKKQALDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIEN----------- 69
Cdd:PRK10982 248 EVILEVRNLTSL--RQPSIRDVSFDLHKGeILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNhnaneainhgf 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 70 ---TKEIRN--MVGYLPQDF-SMYPNMTVYKamDYLAVLSDIPLRKRRK-IIAKLLSKvnlTNYQNMKVKSLSGGMNRRL 142
Cdd:PRK10982 326 alvTEERRStgIYAYLDIGFnSLISNIRNYK--NKVGLLDNSRMKSDTQwVIDSMRVK---TPGHRTQIGSLSGGNQQKV 400
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 143 GIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIAN-DRIVILSTHIVGDIEATCENVAILDSGKV 210
Cdd:PRK10982 401 IIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKkDKGIIIISSEMPELLGITDRILVMSNGLV 469
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
33-195 |
1.87e-05 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 43.90 E-value: 1.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 33 GLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPientkeirnmvgylpqdfsmypnmtvykamdylavlsdiplrkrrk 112
Cdd:smart00382 6 LIVGPPGSGKTTLARALARELGPPGGGVIYIDGE---------------------------------------------- 39
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 113 IIAKLLSKVNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLC-------EIANDRIV 185
Cdd:smart00382 40 DILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrlllllKSEKNLTV 119
|
170
....*....|
gi 544973757 186 ILSTHIVGDI 195
Cdd:smart00382 120 ILTTNDEKDL 129
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
4-219 |
2.46e-05 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 44.90 E-value: 2.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 4 KIAVSNLSKRFGK--KQALDNINLEIDSGM-FGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGVPIENT--KEIRNMVG 78
Cdd:cd03288 19 EIKIHDLCVRYENnlKPVLKHVKAYIKPGQkVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLplHTLRSRLS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 79 YLPQDFSMYPNmTVYKAMDYLAVLSDiplrkrrkiiAKLLSKVNLTNYQNMkVKSLSGGMN--------------RRL-G 143
Cdd:cd03288 99 IILQDPILFSG-SIRFNLDPECKCTD----------DRLWEALEIAQLKNM-VKSLPGGLDavvteggenfsvgqRQLfC 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 544973757 144 IAQALIHNPRVLIVDEPTAGLD-PEERIRFRNLLCEIAnDRIVILSTHIVGDIeATCENVAILDSGKVIYNGSTEAL 219
Cdd:cd03288 167 LARAFVRKSSILIMDEATASIDmATENILQKVVMTAFA-DRTVVTIAHRVSTI-LDADLVLVLSRGILVECDTPENL 241
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
131-216 |
2.71e-05 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 43.50 E-value: 2.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 131 VKSLSGGMNRRLGIAQALIH---NPRVL-IVDEPTAGLDPEERIRFRNLLCEIA-NDRIVILSTHivgDIEATCENVAIL 205
Cdd:cd03227 75 RLQLSGGEKELSALALILALaslKPRPLyILDEIDRGLDPRDGQALAEAILEHLvKGAQVIVITH---LPELAELADKLI 151
|
90
....*....|.
gi 544973757 206 DSGKVIYNGST 216
Cdd:cd03227 152 HIKKVITGVYK 162
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
108-219 |
2.84e-05 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 44.79 E-value: 2.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 108 RKRRKIiaKLLSKVNLTNYQNMkVKS----LSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEI--AN 181
Cdd:PRK15093 132 RKRRAI--ELLHRVGIKDHKDA-MRSfpyeLTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLnqNN 208
|
90 100 110
....*....|....*....|....*....|....*...
gi 544973757 182 DRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEAL 219
Cdd:PRK15093 209 NTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKEL 246
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
133-190 |
3.71e-05 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 44.30 E-value: 3.71e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 133 SLSGGMNRRLGIAQALI---HNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRI-VILSTH 190
Cdd:pfam13304 236 ELSDGTKRLLALLAALLsalPKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGAqLILTTH 297
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
33-219 |
4.49e-05 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 44.97 E-value: 4.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 33 GLLGRNGAGKTTFMRILATLLSKTEGSIHM--CGVPIENTKEIRNMVGYLPQDFSMYPNmTVYKAMDYLAVLSDIPLRK- 109
Cdd:PLN03232 1266 GVVGRTGAGKSSMLNALFRIVELEKGRIMIddCDVAKFGLTDLRRVLSIIPQSPVLFSG-TVRFNIDPFSEHNDADLWEa 1344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 110 -RRKIIAKLLSK--VNLTNYQNMKVKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRIVI 186
Cdd:PLN03232 1345 lERAHIKDVIDRnpFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVRTDSLIQRTIREEFKSCTML 1424
|
170 180 190
....*....|....*....|....*....|...
gi 544973757 187 LSTHIVGDIeATCENVAILDSGKVIYNGSTEAL 219
Cdd:PLN03232 1425 VIAHRLNTI-IDCDKILVLSSGQVLEYDSPQEL 1456
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
23-167 |
5.24e-05 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 44.35 E-value: 5.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 23 INLEIDSGMFGL-LGRNGAGKTTFMRILATLLSKTEGSIhmcgvpienTKEIRNMVGYLPQDfsmyPNMTVYKAMDYLAV 101
Cdd:TIGR00954 471 LSFEVPSGNNLLiCGPNGCGKSSLFRILGELWPVYGGRL---------TKPAKGKLFYVPQR----PYMTLGTLRDQIIY 537
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 102 LSDIPLRKRR----KIIAKLLSKVNLTNY----------QNMKvKSLSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE 167
Cdd:TIGR00954 538 PDSSEDMKRRglsdKDLEQILDNVQLTHIlereggwsavQDWM-DVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVD 616
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
20-190 |
5.58e-05 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 44.22 E-value: 5.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 20 LDNINLEIDSGMFGLLGRNGAGKTTFMRILATLLSKTEGS------IHMCGVPIENTKEI--------RNMVGYLP---- 81
Cdd:COG3593 14 IKDLSIELSDDLTVLVGENNSGKSSILEALRLLLGPSSSRkfdeedFYLGDDPDLPEIEIeltfgsllSRLLRLLLkeed 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 82 -------------------QDFSMYPNMTVYKAMDYLAVLSDIPLRKRRKIIAKLlsKVNLTNYQNMKVKSLSGGMNRRL 142
Cdd:COG3593 94 keeleealeelneelkealKALNELLSEYLKELLDGLDLELELSLDELEDLLKSL--SLRIEDGKELPLDRLGSGFQRLI 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 544973757 143 GIA--QALIH-----NPRVLIVDEPTAGLDPEERIRFRNLLCEIANDRI-VILSTH 190
Cdd:COG3593 172 LLAllSALAElkrapANPILLIEEPEAHLHPQAQRRLLKLLKELSEKPNqVIITTH 227
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
20-219 |
3.51e-04 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 42.24 E-value: 3.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 20 LDNINLEIDSG-MFGLLGRNGAGKTTFMRILATLLSKTEGSIHMCGvpientkeirnMVGYLPQD-------------FS 85
Cdd:TIGR00957 654 LNGITFSIPEGaLVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKG-----------SVAYVPQQawiqndslrenilFG 722
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 86 MYPNMTVYKA-MDYLAVLSDI---PLRKRRKIIAKllsKVNLtnyqnmkvkslSGGMNRRLGIAQALIHNPRVLIVDEPT 161
Cdd:TIGR00957 723 KALNEKYYQQvLEACALLPDLeilPSGDRTEIGEK---GVNL-----------SGGQKQRVSLARAVYSNADIYLFDDPL 788
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 544973757 162 AGLDPE--ERIrFRNLLCE--IANDRIVILSTHIVGDIEATcENVAILDSGKVIYNGSTEAL 219
Cdd:TIGR00957 789 SAVDAHvgKHI-FEHVIGPegVLKNKTRILVTHGISYLPQV-DVIIVMSGGKISEMGSYQEL 848
|
|
| COG3950 |
COG3950 |
Predicted ATP-binding protein involved in virulence [General function prediction only]; |
22-129 |
4.42e-04 |
|
Predicted ATP-binding protein involved in virulence [General function prediction only];
Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 41.14 E-value: 4.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 22 NINLEIDSGMFGLLGRNGAGKTTFMRILATLLSKTEGSIhmcgvpieNTKEIRNMVGYLPQDFSMYPNMTVYKAMDYlav 101
Cdd:COG3950 18 EIDFDNPPRLTVLVGENGSGKTTLLEAIALALSGLLSRL--------DDVKFRKLLIRNGEFGDSAKLILYYGTSRL--- 86
|
90 100
....*....|....*....|....*...
gi 544973757 102 LSDIPLRKRRKIIAKLLSKvnLTNYQNM 129
Cdd:COG3950 87 LLDGPLKKLERLKEEYFSR--LDGYDSL 112
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
4-191 |
5.72e-04 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 40.38 E-value: 5.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 4 KIAVSNLsKRFGKKQALDninleIDSGMFGLLGRNGAGKTTFMRILATLL-----SKTEGSIHMCGVPIENT-------- 70
Cdd:COG0419 4 RLRLENF-RSYRDTETID-----FDDGLNLIVGPNGAGKSTILEAIRYALygkarSRSKLRSDLINVGSEEAsvelefeh 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 71 ----------------------KEIRNMVGYLPQDfsmypnMTVYKAMDYLAVLSDIP------LRKRRKIIAKLLSKvn 122
Cdd:COG0419 78 ggkryrierrqgefaefleakpSERKEALKRLLGL------EIYEELKERLKELEEALesaleeLAELQKLKQEILAQ-- 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 544973757 123 LTNYQNmkVKSLSGGMNRRLGIAQALihnprVLIVDepTAGLDPEERIRFRNLLceianDRIVILSTHI 191
Cdd:COG0419 150 LSGLDP--IETLSGGERLRLALADLL-----SLILD--FGSLDEERLERLLDAL-----EELAIITHVI 204
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
131-190 |
4.85e-03 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 37.59 E-value: 4.85e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 544973757 131 VKSLSGG------MNRRLGIAQALIHNPRVLIVDEPTAGLDPEERirfRNLLCEIANDR--------IVIlsTH 190
Cdd:cd03240 113 RGRCSGGekvlasLIIRLALAETFGSNCGILALDEPTTNLDEENI---EESLAEIIEERksqknfqlIVI--TH 181
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
3-55 |
6.31e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 37.82 E-value: 6.31e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 544973757 3 MKIAVSNLsKRFGKkqaLDNINLEIDSGMFGLLGRNGAGKTTFMR-ILATLLSK 55
Cdd:COG4717 1 MKIKELEI-YGFGK---FRDRTIEFSPGLNVIYGPNEAGKSTLLAfIRAMLLER 50
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
134-221 |
8.35e-03 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 37.84 E-value: 8.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544973757 134 LSGGMNRRLGIAQALIHNPRVLIVDEPTAGLDPE--ERIrFRNLLCEIANDRIVILSTHIVgDIEATCENVAILDSGKVI 211
Cdd:PTZ00243 783 LSGGQKARVSLARAVYANRDVYLLDDPLSALDAHvgERV-VEECFLGALAGKTRVLATHQV-HVVPRADYVVALGDGRVE 860
|
90
....*....|
gi 544973757 212 YNGSTEALAK 221
Cdd:PTZ00243 861 FSGSSADFMR 870
|
|
| |
