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Conserved domains on  [gi|545061593|ref|WP_021434662|]
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glycine rich domain-containing protein [Clostridioides difficile]

Protein Classification

glycine rich domain-containing protein( domain architecture ID 12122583)

glycine rich domain-containing protein similar to the glycine rich domain region of Caenorhabditis elegans ALK tyrosine kinase receptor homolog scd-2, a probable tyrosine-protein kinase receptor which regulates the dauer/non-dauer developmental decision probably by controlling daf-3 transcriptional activity in parallel or together with the TGF-beta pathway

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Gly_rich pfam12810
Glycine rich protein; This family of proteins is greatly expanded in Trichomonas vaginalis. ...
 12-259 4.62e-29

Glycine rich protein; This family of proteins is greatly expanded in Trichomonas vaginalis. The proteins are composed of several glycine rich motifs interspersed through the sequence. Although many proteins have been annotated by similarity in the family these annotations given the biased composition of the sequences these are unlikely to be functionally relevant.


:

Pssm-ID: 403882 [Multi-domain]  Cd Length: 257  Bit Score: 115.84  E-value: 4.62e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545061593   12 TGKKVILKPGKYKLECWGASGGGRFDEWTECAKGGYSKGELTLKKETILYVYAGESGYKKFSNISDWAGFNGGGRGPNEG 91
Cdd:pfam12810   1 TPYEVTLPPGLYKFELWGASGGSSTNDSSIGGKGGYSSGILTLKKSTTLYLYVGGKGEYNNSTNMNPGGFNGGGNYKGSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545061593   92 VDPkfTTCGGGATDIrliggvWNDEQGLLSRIIVA------GGGGSIGTSSFSSIglgggFAGGMGVGAGTTCTGGTQYE 165
Cdd:pfam12810  81 GDG--SGGGGGATDI------RFDENSLKSRIIVAgggggsGEGDDGSGGYGGGL-----TGGGGGSGCYEGSYGATQTS 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545061593  166 GGvTVNSNGNGSFGKGGIGNVCAGGGGWYG-------GAGASSSGVGGGGSGYVLTKDSYkPKGYIPTSEYWLENVNSIA 238
Cdd:pfam12810 148 GG-IGGYGINGSFGQGGNGRNSGGGGGGGGgggyyggFGGGSYGGGGGGGSSYISGKDSH-PYSFIHYSGYLFTNVITIS 225

                         250       260       270
                  ....*....|....*....|....*....|..
gi 545061593  239 GDNTS-----------NAHGYAKITLLQALPF 259
Cdd:pfam12810 226 GNETMpspdgtteignSGNGYARITILSYIKC 257
 
Name Accession Description Interval E-value
Gly_rich pfam12810
Glycine rich protein; This family of proteins is greatly expanded in Trichomonas vaginalis. ...
 12-259 4.62e-29

Glycine rich protein; This family of proteins is greatly expanded in Trichomonas vaginalis. The proteins are composed of several glycine rich motifs interspersed through the sequence. Although many proteins have been annotated by similarity in the family these annotations given the biased composition of the sequences these are unlikely to be functionally relevant.


Pssm-ID: 403882 [Multi-domain]  Cd Length: 257  Bit Score: 115.84  E-value: 4.62e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545061593   12 TGKKVILKPGKYKLECWGASGGGRFDEWTECAKGGYSKGELTLKKETILYVYAGESGYKKFSNISDWAGFNGGGRGPNEG 91
Cdd:pfam12810   1 TPYEVTLPPGLYKFELWGASGGSSTNDSSIGGKGGYSSGILTLKKSTTLYLYVGGKGEYNNSTNMNPGGFNGGGNYKGSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545061593   92 VDPkfTTCGGGATDIrliggvWNDEQGLLSRIIVA------GGGGSIGTSSFSSIglgggFAGGMGVGAGTTCTGGTQYE 165
Cdd:pfam12810  81 GDG--SGGGGGATDI------RFDENSLKSRIIVAgggggsGEGDDGSGGYGGGL-----TGGGGGSGCYEGSYGATQTS 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545061593  166 GGvTVNSNGNGSFGKGGIGNVCAGGGGWYG-------GAGASSSGVGGGGSGYVLTKDSYkPKGYIPTSEYWLENVNSIA 238
Cdd:pfam12810 148 GG-IGGYGINGSFGQGGNGRNSGGGGGGGGgggyyggFGGGSYGGGGGGGSSYISGKDSH-PYSFIHYSGYLFTNVITIS 225

                         250       260       270
                  ....*....|....*....|....*....|..
gi 545061593  239 GDNTS-----------NAHGYAKITLLQALPF 259
Cdd:pfam12810 226 GNETMpspdgtteignSGNGYARITILSYIKC 257
 
Name Accession Description Interval E-value
Gly_rich pfam12810
Glycine rich protein; This family of proteins is greatly expanded in Trichomonas vaginalis. ...
 12-259 4.62e-29

Glycine rich protein; This family of proteins is greatly expanded in Trichomonas vaginalis. The proteins are composed of several glycine rich motifs interspersed through the sequence. Although many proteins have been annotated by similarity in the family these annotations given the biased composition of the sequences these are unlikely to be functionally relevant.


Pssm-ID: 403882 [Multi-domain]  Cd Length: 257  Bit Score: 115.84  E-value: 4.62e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545061593   12 TGKKVILKPGKYKLECWGASGGGRFDEWTECAKGGYSKGELTLKKETILYVYAGESGYKKFSNISDWAGFNGGGRGPNEG 91
Cdd:pfam12810   1 TPYEVTLPPGLYKFELWGASGGSSTNDSSIGGKGGYSSGILTLKKSTTLYLYVGGKGEYNNSTNMNPGGFNGGGNYKGSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545061593   92 VDPkfTTCGGGATDIrliggvWNDEQGLLSRIIVA------GGGGSIGTSSFSSIglgggFAGGMGVGAGTTCTGGTQYE 165
Cdd:pfam12810  81 GDG--SGGGGGATDI------RFDENSLKSRIIVAgggggsGEGDDGSGGYGGGL-----TGGGGGSGCYEGSYGATQTS 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545061593  166 GGvTVNSNGNGSFGKGGIGNVCAGGGGWYG-------GAGASSSGVGGGGSGYVLTKDSYkPKGYIPTSEYWLENVNSIA 238
Cdd:pfam12810 148 GG-IGGYGINGSFGQGGNGRNSGGGGGGGGgggyyggFGGGSYGGGGGGGSSYISGKDSH-PYSFIHYSGYLFTNVITIS 225

                         250       260       270
                  ....*....|....*....|....*....|..
gi 545061593  239 GDNTS-----------NAHGYAKITLLQALPF 259
Cdd:pfam12810 226 GNETMpspdgtteignSGNGYARITILSYIKC 257
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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