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Conserved domains on  [gi|545130686|ref|WP_021492106|]
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MULTISPECIES: ABC transporter ATP-binding protein [Pseudomonas]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467437)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including Fe(3+) ions and polyamines such as spermidine and putrescine

CATH:  3.40.50.300
EC:  7.-.-.-
Gene Ontology:  GO:0042626|GO:0140359|GO:0005524|GO:0016887
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-325 2.76e-172

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


:

Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 481.91  E-value: 2.76e-172
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMV 80
Cdd:COG3842    3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGMV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:COG3842   83 FQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEP 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 161 LSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLL 240
Cdd:COG3842  163 LSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEANLL 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 241 DA------DKATQLLQRPISSR------------IAIRPEAIELSRTGE---LDALVRSHSLLGNVIRYRIE-ARGVELV 298
Cdd:COG3842  243 PGtvlgdeGGGVRTGGRTLEVPadaglaaggpvtVAIRPEDIRLSPEGPengLPGTVEDVVFLGSHVRYRVRlGDGQELV 322

                        330       340
                 ....*....|....*....|....*..
gi 545130686 299 VDVLNRSADDLHPdGQRLALSIDPSAL 325
Cdd:COG3842  323 VRVPNRAALPLEP-GDRVGLSWDPEDV 348
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-325 2.76e-172

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 481.91  E-value: 2.76e-172
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMV 80
Cdd:COG3842    3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGMV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:COG3842   83 FQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEP 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 161 LSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLL 240
Cdd:COG3842  163 LSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEANLL 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 241 DA------DKATQLLQRPISSR------------IAIRPEAIELSRTGE---LDALVRSHSLLGNVIRYRIE-ARGVELV 298
Cdd:COG3842  243 PGtvlgdeGGGVRTGGRTLEVPadaglaaggpvtVAIRPEDIRLSPEGPengLPGTVEDVVFLGSHVRYRVRlGDGQELV 322

                        330       340
                 ....*....|....*....|....*..
gi 545130686 299 VDVLNRSADDLHPdGQRLALSIDPSAL 325
Cdd:COG3842  323 VRVPNRAALPLEP-GDRVGLSWDPEDV 348
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 1-325 1.06e-132

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 381.69  E-value: 1.06e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMV 80
Cdd:TIGR03265   2 SPYLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQKRDYGIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   81 FQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:TIGR03265  82 FQSYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLDEP 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  161 LSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLL 240
Cdd:TIGR03265 162 LSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVNWL 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  241 DA---------------DKATQLLQRPISSRIAIRPEAIELSRTGE----LDALVRSHSLLGNviRYRIEAR-----GVE 296
Cdd:TIGR03265 242 PGtrgggsrarvggltlACAPGLAQPGASVRLAVRPEDIRVSPAGNaanlLLARVEDMEFLGA--FYRLRLRleglpGQA 319

                         330       340       350
                  ....*....|....*....|....*....|.
gi 545130686  297 LVVDVLnRSADDLHPD--GQRLALSIDPSAL 325
Cdd:TIGR03265 320 LVADVS-ASEVERLGIraGQPIWIELPAERL 349
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 4-235 1.69e-124

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 356.16  E-value: 1.69e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQS 83
Cdd:cd03300    1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:cd03300   81 YALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 545130686 164 LDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIG 235
Cdd:cd03300  161 LDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1-242 1.06e-121

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 354.64  E-value: 1.06e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMV 80
Cdd:PRK09452  12 SPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENRHVNTV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:PRK09452  92 FQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDES 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 161 LSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLL 240
Cdd:PRK09452 172 LSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGEINIF 251


                 ..
gi 545130686 241 DA 242
Cdd:PRK09452 252 DA 253
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
6-309 4.15e-90

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 273.10  E-value: 4.15e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYAGTPVfSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQSYA 85
Cdd:NF040840   4 IENLSKDWKEFKL-RDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLPPEKRGIAYVYQNYM 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  86 LFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD 165
Cdd:NF040840  83 LFPHKTVFENIAFGLKLRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALD 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 166 ARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLLD--AD 243
Cdd:NF040840 163 VQTRDELIREMKRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVGFENIIEgvAE 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 244 KATQL---------LQRPISS----RIAIRPEAIELSRTG-------ELDALVRSHSLLGNVIRYRIEArGVELVVDVLN 303
Cdd:NF040840 243 KGGEGtildtgnikIELPEEKkgkvRIGIRPEDITISTEKvktsarnEFKGKVEEIEDLGPLVKLTLDV-GIILVAFITR 321


                 ....*.
gi 545130686 304 RSADDL 309
Cdd:NF040840 322 SSFLDL 327
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 19-162 3.90e-50

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 163.97  E-value: 3.90e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   19 FSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFPNMTVEQNV 96
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKslRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   97 AFGLRMQKVNADDSHKRVQEVLQLVELKDLA----GRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLAdrpvGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
12-206 4.93e-34

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 123.50  E-value: 4.93e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  12 SYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGmvfqsyALFPnMT 91
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVAYVPQRSEVP------DSLP-LT 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  92 VEQNVAFGL-----RMQKVNADDsHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDA 166
Cdd:NF040873  74 VRDLVAMGRwarrgLWRRLTRDD-RAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDA 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 545130686 167 RIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFL 206
Cdd:NF040873 153 ESRERIIALLAEEHAR-GATVVVVTHDLELVRRADPCVLL 191
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
21-221 7.31e-21

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 93.27  E-value: 7.31e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP--LSPQKRhIGMVFQSYALFPNMTVEQNVAF 98
Cdd:NF033858 284 HVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAgdIATRRR-VGYMSQAFSLYGELTVRQNLEL 362

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  99 GLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQ 178
Cdd:NF033858 363 HARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIE 442

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 545130686 179 IQRELGLtTIFV-THDQEEALTmSDRIFLMNQGK---------IVQSGDAETL 221
Cdd:NF033858 443 LSREDGV-TIFIsTHFMNEAER-CDRISLMHAGRvlasdtpaaLVAARGAATL 493
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
101-223 3.48e-16

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 78.24  E-value: 3.48e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 101 RMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQ 180
Cdd:NF000106 112 R*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMV 191

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 545130686 181 RElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYT 223
Cdd:NF000106 192 RD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKT 233
GguA NF040905
sugar ABC transporter ATP-binding protein;
11-220 5.06e-15

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 75.60  E-value: 5.06e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  11 KSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDS--GKILLDGQ-----DIVplSPQKRHIGMVFQS 83
Cdd:NF040905   9 KTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGSyeGEILFDGEvcrfkDIR--DSEALGIVIIHQE 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YALFPNMTVEQNVAFGLRMQK---VNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:NF040905  87 LALIPYLSIAENIFLGNERAKrgvIDWNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILDEP 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 161 LSALDARIRKHLREQIRQIqRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAET 220
Cdd:NF040905 167 TAALNEEDSAALLDLLLEL-KAQGITSIIISHKLNEIRRVADSITVLRDGRTIETLDCRA 225
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4-221 3.94e-14

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 73.24  E-value: 3.94e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVplspQKRHIGMVFQS 83
Cdd:NF033858   2 ARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMA----DARHRRAVCPR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YA---------LFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRL 154
Cdd:NF033858  78 IAympqglgknLYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 155 LLLDEPLSALDARIRKHLREQIRQIQREL-GLTTIFVTHDQEEALTMsDRIFLMNQGKIVQSGDAETL 221
Cdd:NF033858 158 LILDEPTTGVDPLSRRQFWELIDRIRAERpGMSVLVATAYMEEAERF-DWLVAMDAGRVLATGTPAEL 224
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 28-206 1.12e-11

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 62.01  E-value: 1.12e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    28 KGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLdgqdivplspqkrhigmvfqsyalfpnmtveqnvafglrmqkVNA 107
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY------------------------------------------IDG 38

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   108 DDSHKRVQEVLQLVelkdLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIR-----QIQRE 182
Cdd:smart00382  39 EDILEEVLDQLLLI----IVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrlllLLKSE 114

                          170       180
                   ....*....|....*....|....
gi 545130686   183 LGLTTIFVTHDQEEALTMSDRIFL 206
Cdd:smart00382 115 KNLTVILTTNDEKDLGPALLRRRF 138
GguA NF040905
sugar ABC transporter ATP-binding protein;
5-213 5.58e-07

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 50.94  E-value: 5.58e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQksYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLT--SVDSGKILLDGQDIVpLSPQKRHI--GMV 80
Cdd:NF040905 264 TVYHPL--HPERKVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGRSygRNISGTVFKDGKEVD-VSTVSDAIdaGLA 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 F-----QSYALFPNMTVEQNVAFGlRMQKVnaddSHKRVqeVLQLVELKdLAGRYPHQM--------------SGGQCQR 141
Cdd:NF040905 341 YvtedrKGYGLNLIDDIKRNITLA-NLGKV----SRRGV--IDENEEIK-VAEEYRKKMniktpsvfqkvgnlSGGNQQK 412

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 142 VALARSLVTRPRLLLLDEPLSALD--ARIrkhlreQIRQIQREL---GLTTIFVTHDQEEALTMSDRIFLMNQGKIV 213
Cdd:NF040905 413 VVLSKWLFTDPDVLILDEPTRGIDvgAKY------EIYTIINELaaeGKGVIVISSELPELLGMCDRIYVMNEGRIT 483
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-325 2.76e-172

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 481.91  E-value: 2.76e-172
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMV 80
Cdd:COG3842    3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKRNVGMV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:COG3842   83 FQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEP 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 161 LSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLL 240
Cdd:COG3842  163 LSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEANLL 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 241 DA------DKATQLLQRPISSR------------IAIRPEAIELSRTGE---LDALVRSHSLLGNVIRYRIE-ARGVELV 298
Cdd:COG3842  243 PGtvlgdeGGGVRTGGRTLEVPadaglaaggpvtVAIRPEDIRLSPEGPengLPGTVEDVVFLGSHVRYRVRlGDGQELV 322

                        330       340
                 ....*....|....*....|....*..
gi 545130686 299 VDVLNRSADDLHPdGQRLALSIDPSAL 325
Cdd:COG3842  323 VRVPNRAALPLEP-GDRVGLSWDPEDV 348
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 1-325 8.31e-143

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 407.15  E-value: 8.31e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMV 80
Cdd:COG3839    1 MASLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKDRNIAMV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:COG3839   81 FQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLLDEP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 161 LSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNY--N 238
Cdd:COG3839  161 LSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELYDRPANLFVAGFIGSPpmN 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 239 LLDADKATQLLQR-----PISSR----------IAIRPEAIELSRTGE--LDALVRSHSLLGNVIRYRIEARGVELVVDV 301
Cdd:COG3839  241 LLPGTVEGGGVRLggvrlPLPAAlaaaaggevtLGIRPEHLRLADEGDggLEATVEVVEPLGSETLVHVRLGGQELVARV 320

                        330       340
                 ....*....|....*....|....
gi 545130686 302 lnrSADDLHPDGQRLALSIDPSAL 325
Cdd:COG3839  321 ---PGDTRLRPGDTVRLAFDPERL 341
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 1-325 1.06e-132

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 381.69  E-value: 1.06e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMV 80
Cdd:TIGR03265   2 SPYLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQKRDYGIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   81 FQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:TIGR03265  82 FQSYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLDEP 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  161 LSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLL 240
Cdd:TIGR03265 162 LSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVNWL 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  241 DA---------------DKATQLLQRPISSRIAIRPEAIELSRTGE----LDALVRSHSLLGNviRYRIEAR-----GVE 296
Cdd:TIGR03265 242 PGtrgggsrarvggltlACAPGLAQPGASVRLAVRPEDIRVSPAGNaanlLLARVEDMEFLGA--FYRLRLRleglpGQA 319

                         330       340       350
                  ....*....|....*....|....*....|.
gi 545130686  297 LVVDVLnRSADDLHPD--GQRLALSIDPSAL 325
Cdd:TIGR03265 320 LVADVS-ASEVERLGIraGQPIWIELPAERL 349
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 1-325 2.63e-130

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 375.25  E-value: 2.63e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSfVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI-VPLSPQKRHIGM 79
Cdd:COG1118    1 MS-IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLfTNLPPRERRVGF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDE 159
Cdd:COG1118   80 VFQHYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 160 PLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNL 239
Cdd:COG1118  160 PFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFLGCVNV 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 240 LD---------ADKATQLLQRPISSRIA---IRPEAIELSRTGE----LDALVRSHSLLGNVIRYRIEARGVE---LVVD 300
Cdd:COG1118  240 LRgrviggqleADGLTLPVAEPLPDGPAvagVRPHDIEVSREPEgentFPATVARVSELGPEVRVELKLEDGEgqpLEAE 319

                        330       340
                 ....*....|....*....|....*.
gi 545130686 301 VLNRSADDLHPD-GQRLALSIDPSAL 325
Cdd:COG1118  320 VTKEAWAELGLApGDPVYLRPRPARV 345
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 4-235 1.69e-124

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 356.16  E-value: 1.69e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQS 83
Cdd:cd03300    1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRPVNTVFQN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:cd03300   81 YALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 545130686 164 LDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIG 235
Cdd:cd03300  161 LDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1-242 1.06e-121

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 354.64  E-value: 1.06e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMV 80
Cdd:PRK09452  12 SPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENRHVNTV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:PRK09452  92 FQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDES 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 161 LSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLL 240
Cdd:PRK09452 172 LSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIGEINIF 251


                 ..
gi 545130686 241 DA 242
Cdd:PRK09452 252 DA 253
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 4-216 3.68e-115

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 331.79  E-value: 3.68e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQS 83
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERRNIGMVFQD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:cd03259   81 YALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSA 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 545130686 164 LDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03259  161 LDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 34-323 6.13e-109

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 320.21  E-value: 6.13e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   34 LLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKR 113
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRAEIKPR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  114 VQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHD 193
Cdd:TIGR01187  81 VLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITFVFVTHD 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  194 QEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLLDA-------------------DKATQLLQRPIS 254
Cdd:TIGR01187 161 QEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEAtvierkseqvvlagvegrrCDIYTDVPVEKD 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  255 SR--IAIRPEAIELSRTGE------LDALVRSHSLLGNVIRY--RIEARGVELVVDVLNrsADDLHPD---GQRLALSID 321
Cdd:TIGR01187 241 QPlhVVLRPEKIVIEEEDEanssnaIIGHVIDITYLGMTLEVhvRLETGQKVLVSEFFN--EDDPHMSpsiGDRVGLTWH 318


                  ..
gi 545130686  322 PS 323
Cdd:TIGR01187 319 PG 320
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
2-322 5.31e-107

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 316.28  E-value: 5.31e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   2 SFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVF 81
Cdd:PRK11432   5 NFVVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQRDICMVF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 QSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:PRK11432  85 QSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 162 SALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLLD 241
Cdd:PRK11432 165 SNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFMGDANIFP 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 242 ADKATQ-------LLQRPI---------SSRIAIRPEAIELSRTGELD--ALVRSHSLLGNVIRYRIEARGVELvvdVLN 303
Cdd:PRK11432 245 ATLSGDyvdiygyRLPRPAafafnlpdgECTVGVRPEAITLSEQGEESqrCTIKHVAYMGPQYEVTVDWHGQEL---LLQ 321

                        330       340
                 ....*....|....*....|
gi 545130686 304 RSADDLHPD-GQRLALSIDP 322
Cdd:PRK11432 322 VNATQLQPDlGEHYYLEIHP 341
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 1-236 1.57e-102

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 300.80  E-value: 1.57e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSfVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMV 80
Cdd:cd03296    1 MS-IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQERNVGFV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGLRMQKV----NADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:cd03296   80 FQHYALFRHMTVFDNVAFGLRVKPRserpPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGN 236
Cdd:cd03296  160 LDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSFLGE 239
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-207 3.45e-102

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 300.47  E-value: 3.45e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYA----GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPqkrH 76
Cdd:COG1116    5 APALELRGVSKRFPtgggGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGP---D 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  77 IGMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:COG1116   82 RGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLL 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLM 207
Cdd:COG1116  162 MDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVL 212
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 4-216 1.43e-99

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 292.24  E-value: 1.43e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQS 83
Cdd:cd03301    1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDRDIAMVFQN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:cd03301   81 YALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSN 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 545130686 164 LDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03301  161 LDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1-325 1.76e-99

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 297.14  E-value: 1.76e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAG-TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGM 79
Cdd:PRK11650   1 MAGLKLQAVRKSYDGkTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPADRDIAM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDE 159
Cdd:PRK11650  81 VFQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFLFDE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 160 PLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGN--Y 237
Cdd:PRK11650 161 PLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVYEKPASTFVASFIGSpaM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 238 NLLDADKATQLLQRPISSRIA------------------IRPEAIELSR-TGELDALVRSHSLLG--NVIRYRIEarGVE 296
Cdd:PRK11650 241 NLLDGRVSADGAAFELAGGIAlplgggyrqyagrkltlgIRPEHIALSSaEGGVPLTVDTVELLGadNLAHGRWG--GQP 318

                        330       340
                 ....*....|....*....|....*....
gi 545130686 297 LVVDVLNRSAddlHPDGQRLALSIDPSAL 325
Cdd:PRK11650 319 LVVRLPHQER---PAAGSTLWLHLPANQL 344
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 4-214 1.66e-96

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 284.75  E-value: 1.66e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAG----TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdivPLSPQKRHIGM 79
Cdd:cd03293    1 LEVRNVSKTYGGgggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGE---PVTGPGPDRGY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDE 159
Cdd:cd03293   78 VFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDE 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 160 PLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQ--GKIVQ 214
Cdd:cd03293  158 PFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLSArpGRIVA 214
3a0106s01 TIGR00968
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
 4-240 5.05e-96

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]


Pssm-ID: 130041 [Multi-domain]  Cd Length: 237  Bit Score: 284.00  E-value: 5.05e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQS 83
Cdd:TIGR00968   1 IEIANISKRFGSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDSGRIRLNGQDATRVHARDRKIGFVFQH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   84 YALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:TIGR00968  81 YALFKHLTVRDNIAFGLEIRKHPKAKIKARVEELLELVQLEGLGDRYPNQLSGGQRQRVALARALAVEPQVLLLDEPFGA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686  164 LDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLL 240
Cdd:TIGR00968 161 LDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFLGEVNVL 237
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
6-241 6.71e-94

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 283.65  E-value: 6.71e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQSYA 85
Cdd:PRK11607  22 IRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRPINMMFQSYA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  86 LFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD 165
Cdd:PRK11607 102 LFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALD 181

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 166 ARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLLD 241
Cdd:PRK11607 182 KKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFE 257
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 7-276 1.09e-91

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 275.43  E-value: 1.09e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   7 QHLQKSYA-GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMVFQS 83
Cdd:COG1125    5 ENVTKRYPdGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRDLDPVElrRRIGYVIQQ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVEL--KDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:COG1125   85 IGLFPHMTVAENIATVPRLLGWDKERIRARVDELLELVGLdpEEYRDRYPHELSGGQQQRVGVARALAADPPILLMDEPF 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 162 SALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIG---NYN 238
Cdd:COG1125  165 GALDPITREQLQDELLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILANPANDFVADFVGadrGLR 244

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 545130686 239 LLDADKATQLLQRPIssrIAIRP-----EAIELSRTGELDALV 276
Cdd:COG1125  245 RLSLLRVEDLMLPEP---PTVSPdaslrEALSLMLERGVDWLL 284
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
1-273 1.65e-91

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 276.96  E-value: 1.65e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSfVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMV 80
Cdd:PRK10851   1 MS-IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGLRM----QKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:PRK10851  80 FQHYALFRHMTVFDNIAFGLTVlprrERPNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGN 236
Cdd:PRK10851 160 LDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFMGE 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 545130686 237 YNLLDAD-KATQLL----QRPISSRIA--------IRPEAIELSRTGELD 273
Cdd:PRK10851 240 VNRLQGTiRGGQFHvgahRWPLGYTPAyqgpvdlfLRPWEVDISRRTSLD 289
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 6-239 3.61e-90

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 269.21  E-value: 3.61e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYaGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQSYA 85
Cdd:cd03299    3 VENLSKDW-KEFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKRDISYVPQNYA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  86 LFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD 165
Cdd:cd03299   82 LFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALD 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 166 ARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNL 239
Cdd:cd03299  162 VRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFLGFNNI 235
tungstate_WtpC NF040840
tungstate ABC transporter ATP-binding protein WtpC;
6-309 4.15e-90

tungstate ABC transporter ATP-binding protein WtpC;


Pssm-ID: 468779 [Multi-domain]  Cd Length: 347  Bit Score: 273.10  E-value: 4.15e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYAGTPVfSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQSYA 85
Cdd:NF040840   4 IENLSKDWKEFKL-RDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLPPEKRGIAYVYQNYM 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  86 LFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD 165
Cdd:NF040840  83 LFPHKTVFENIAFGLKLRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSALD 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 166 ARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLLD--AD 243
Cdd:NF040840 163 VQTRDELIREMKRWHREFGFTAIHVTHNFEEALSLADRVGIMLNGRLSQVGDVREVFRRPKNEFVARFVGFENIIEgvAE 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 244 KATQL---------LQRPISS----RIAIRPEAIELSRTG-------ELDALVRSHSLLGNVIRYRIEArGVELVVDVLN 303
Cdd:NF040840 243 KGGEGtildtgnikIELPEEKkgkvRIGIRPEDITISTEKvktsarnEFKGKVEEIEDLGPLVKLTLDV-GIILVAFITR 321


                 ....*.
gi 545130686 304 RSADDL 309
Cdd:NF040840 322 SSFLDL 327
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
1-235 1.78e-88

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 269.59  E-value: 1.78e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMV 80
Cdd:PRK11000   1 MASVTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAERGVGMV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:PRK11000  81 FQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 161 LSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIG 235
Cdd:PRK11000 161 LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANRFVAGFIG 235
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 4-225 7.78e-87

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 260.68  E-value: 7.78e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK-----RHIG 78
Cdd:COG1127    6 IEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKElyelrRRIG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  79 MVFQSYALFPNMTVEQNVAFGLRMQ-KVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:COG1127   86 MLFQGGALFDSLTVFENVAFPLREHtDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEILLY 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 158 DEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:COG1127  166 DEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLASD 233
PhnT TIGR03258
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ...
 4-242 5.31e-86

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.


Pssm-ID: 132302 [Multi-domain]  Cd Length: 362  Bit Score: 263.01  E-value: 5.31e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVD--SGKILLDGQDIVPLSPQKRHIGMVF 81
Cdd:TIGR03258   6 IRIDHLRVAYGANTVLDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVKAAglTGRIAIADRDLTHAPPHKRGLALLF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   82 QSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:TIGR03258  86 QNYALFPHLKVEDNVAFGLRAQKMPKADIAERVADALKLVGLGDAAAHLPAQLSGGMQQRIAIARAIAIEPDVLLLDEPL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  162 SALDARIRKHLREQIRQIQREL-GLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLL 240
Cdd:TIGR03258 166 SALDANIRANMREEIAALHEELpELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDAPADGFAAEFLGAANIL 245


                  ..
gi 545130686  241 DA 242
Cdd:TIGR03258 246 PA 247
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 4-225 1.12e-83

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 252.61  E-value: 1.12e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP----LSPQKRHIGM 79
Cdd:COG1126    2 IEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDskkdINKLRRKVGM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNMTVEQNVAFGLRM-QKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLD 158
Cdd:COG1126   82 VFQQFNLFPHLTVLENVTLAPIKvKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLFD 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 159 EPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:COG1126  162 EPTSALDPELVGEVLDVMRDLAKE-GMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENP 227
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 4-235 1.51e-82

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 249.91  E-value: 1.51e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAG-TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMV 80
Cdd:cd03295    1 IEFENVTKRYGGgKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVElrRKIGYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVEL--KDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLD 158
Cdd:cd03295   81 IQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAADPPLLLMD 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 159 EPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIG 235
Cdd:cd03295  161 EPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFVG 237
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
4-213 5.28e-82

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 248.03  E-value: 5.28e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSY----AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR---- 75
Cdd:COG1136    5 LELRNLTKSYgtgeGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELarlr 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  76 --HIGMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPR 153
Cdd:COG1136   85 rrHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRPK 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 154 LLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDqEEALTMSDRIFLMNQGKIV 213
Cdd:COG1136  165 LILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHD-PELAARADRVIRLRDGRIV 223
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 4-225 1.34e-81

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 256.37  E-value: 1.34e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYA-----GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK---- 74
Cdd:COG1123  261 LEVRNLSKRYPvrgkgGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSlrel 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  75 -RHIGMVFQ--SYALFPNMTVEQNVAFGLRMQKV-NADDSHKRVQEVLQLVEL-KDLAGRYPHQMSGGQCQRVALARSLV 149
Cdd:COG1123  341 rRRVQMVFQdpYSSLNPRMTVGDIIAEPLRLHGLlSRAERRERVAELLERVGLpPDLADRYPHELSGGQRQRVAIARALA 420

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 150 TRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:COG1123  421 LEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANP 496
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 21-234 1.39e-79

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 243.32  E-value: 1.39e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP------QKRHIGMVFQSYALFPNMTVEQ 94
Cdd:cd03294   42 DVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRkelrelRRKKISMVFQSFALLPHRTVLE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  95 NVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLRE 174
Cdd:cd03294  122 NVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQD 201

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 175 QIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFI 234
Cdd:cd03294  202 ELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFF 261
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 4-212 1.37e-77

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 236.62  E-value: 1.37e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAG----TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR---- 75
Cdd:cd03255    1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELaafr 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  76 --HIGMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPR 153
Cdd:cd03255   81 rrHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 154 LLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALtMSDRIFLMNQGKI 212
Cdd:cd03255  161 IILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAE-YADRIIELRDGKI 218
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 4-221 1.13e-76

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 234.70  E-value: 1.13e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK-----RHIG 78
Cdd:cd03261    1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAElyrlrRRMG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  79 MVFQSYALFPNMTVEQNVAFGLRMQ-KVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:cd03261   81 MLFQSGALFDSLTVFENVAFPLREHtRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLY 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 158 DEPLSALDArIRKHLREQ-IRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:cd03261  161 DEPTAGLDP-IASGVIDDlIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 4-225 1.66e-76

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 234.15  E-value: 1.66e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYA-GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMV 80
Cdd:COG1122    1 IELENLSFSYPgGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRElrRKVGLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQS--YALFpNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLD 158
Cdd:COG1122   81 FQNpdDQLF-APTVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLD 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 159 EPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:COG1122  160 EPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDY 225
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 26-216 1.76e-75

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 231.03  E-value: 1.76e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  26 VAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKI------LLDGQDIVPLSPQKRHIGMVFQSYALFPNMTVEQNVAFG 99
Cdd:cd03297   20 DLNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIvlngtvLFDSRKKINLPPQQRKIGLVFQQYALFPHLNVRENLAFG 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 100 LRMQKVNADdsHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQI 179
Cdd:cd03297  100 LKRKRNRED--RISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELKQI 177

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 545130686 180 QRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03297  178 KKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
4-221 4.05e-74

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 228.02  E-value: 4.05e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ-KRHIGMVFQ 82
Cdd:COG1131    1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEvRRRIGYVPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:COG1131   81 EPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPTS 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 163 ALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:COG1131  161 GLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDEL 218
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
 11-285 5.61e-74

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 232.44  E-value: 5.61e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   11 KSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP------QKRHIGMVFQSY 84
Cdd:TIGR01186   1 KKTGGKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMKQSPvelrevRRKKIGMVFQQF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   85 ALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSAL 164
Cdd:TIGR01186  81 ALFPHMTILQNTSLGPELLGWPEQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSAL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  165 DARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLLDADK 244
Cdd:TIGR01186 161 DPLIRDSMQDELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIGKVDLSQVFD 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 545130686  245 ATQLLQRPISSRIAIRP-----EAIELSRTGELDALV---RSHSLLGNV 285
Cdd:TIGR01186 241 AERIAQRMNTGPITKTAdkgprSALQLMRDERVDSLYvvdRQNKLVGVV 289
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 4-212 4.28e-73

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 224.72  E-value: 4.28e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ----KRHIGM 79
Cdd:cd03262    1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNinelRQKVGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNMTVEQNVAFGLR-MQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLD 158
Cdd:cd03262   81 VFQQFNLFPHLTVLENITLAPIkVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFD 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 545130686 159 EPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKI 212
Cdd:cd03262  161 EPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDGRI 213
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 6-211 6.93e-73

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 222.83  E-value: 6.93e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLS----PQKRHIGMVF 81
Cdd:cd03229    3 LKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEdelpPLRRRIGMVF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 QSYALFPNMTVEQNVAFGLrmqkvnaddshkrvqevlqlvelkdlagryphqmSGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:cd03229   83 QDFALFPHLTVLENIALGL----------------------------------SGGQQQRVALARALAMDPDVLLLDEPT 128

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 545130686 162 SALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGK 211
Cdd:cd03229  129 SALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 4-229 9.64e-73

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 225.31  E-value: 9.64e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMVF 81
Cdd:COG1120    2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRElaRRIAYVP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 QSYALFPNMTVEQNVAFGL-----RMQKVNADDsHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:COG1120   82 QEPPAPFGLTVRELVALGRyphlgLFGRPSAED-REAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLL 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPV--DVF 229
Cdd:COG1120  161 LDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLTPELleEVY 235
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 4-221 1.20e-72

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 225.07  E-value: 1.20e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSY----AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP--LSPQKRHI 77
Cdd:COG1124    2 LEVRNLSVSYgqggRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRrrRKAFRRRV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVFQSY--ALFPNMTVEQNVAFGLRMQKVnaDDSHKRVQEVLQLVEL-KDLAGRYPHQMSGGQCQRVALARSLVTRPRL 154
Cdd:COG1124   82 QMVFQDPyaSLHPRHTVDRILAEPLRIHGL--PDREERIAELLEQVGLpPSFLDRYPHQLSGGQRQRVAIARALILEPEL 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 155 LLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:COG1124  160 LLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADL 226
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
4-225 5.72e-72

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 226.11  E-value: 5.72e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAG----TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK----- 74
Cdd:COG1135    2 IELENLSKTFPTkggpVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERElraar 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  75 RHIGMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRL 154
Cdd:COG1135   82 RKIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKV 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 155 LLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDqeealtMS------DRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:COG1135  162 LLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHE------MDvvrricDRVAVLENGRIVEQGPVLDVFANP 232
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 4-216 7.68e-71

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 219.68  E-value: 7.68e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAG----TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR---- 75
Cdd:cd03257    2 LEVKNLSVSFPTgggsVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRkirr 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  76 -HIGMVFQSY--ALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVEL---KDLAGRYPHQMSGGQCQRVALARSLV 149
Cdd:cd03257   82 kEIQMVFQDPmsSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAVLLLLVGVglpEEVLNRYPHELSGGQRQRVAIARALA 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 150 TRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03257  162 LNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
1-214 1.83e-70

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 219.73  E-value: 1.83e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAG----TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKrh 76
Cdd:COG4525    1 MSMLTVRHVSVRYPGggqpQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGADR-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  77 iGMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:COG4525   79 -GVVFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLM--NQGKIVQ 214
Cdd:COG4525  158 MDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVVMspGPGRIVE 217
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
9-235 2.00e-70

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 218.47  E-value: 2.00e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   9 LQKSYAGTPVfsDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQSYALFP 88
Cdd:COG3840    7 LTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAERPVSMLFQENNLFP 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  89 NMTVEQNVAFGLRMQ-KVNADDsHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDAR 167
Cdd:COG3840   85 HLTVAQNIGLGLRPGlKLTAEQ-RAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDPA 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 168 IRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIG 235
Cdd:COG3840  164 LRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYLG 231
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 5-211 3.77e-69

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 214.64  E-value: 3.77e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAG--TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMV 80
Cdd:cd03225    1 ELKNLSFSYPDgaRPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKElrRKVGLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQsyalFP-----NMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLL 155
Cdd:cd03225   81 FQ----NPddqffGPTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDIL 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 156 LLDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGK 211
Cdd:cd03225  157 LLDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
4-216 8.45e-69

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 214.15  E-value: 8.45e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYA-GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK-----RHI 77
Cdd:COG2884    2 IRFENVSKRYPgGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREipylrRRI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:COG2884   82 GVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLA 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545130686 158 DEPLSALD----ARIRKHLREqirqIQReLGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:COG2884  162 DEPTGNLDpetsWEIMELLEE----INR-RGTTVLIATHDLELVDRMPKRVLELEDGRLVRDE 219
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 4-225 1.84e-67

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 211.29  E-value: 1.84e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGT----PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP-----QK 74
Cdd:cd03258    2 IELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGkelrkAR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  75 RHIGMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRL 154
Cdd:cd03258   82 RRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKV 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686 155 LLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:cd03258  162 LLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANP 232
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 4-225 2.00e-67

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 219.77  E-value: 2.00e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAG--TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGL---TSVDSGKILLDGQDIVPLSPQKR--H 76
Cdd:COG1123    5 LEVRDLSVRYPGgdVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLlphGGRISGEVLLDGRDLLELSEALRgrR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  77 IGMVFQS--YALFPnMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRL 154
Cdd:COG1123   85 IGMVFQDpmTQLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDL 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686 155 LLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:COG1123  164 LIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAP 234
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 21-297 1.23e-66

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 213.04  E-value: 1.23e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDG---QD---IVPLSPQKRHIGMVFQSYALFPNMTVEQ 94
Cdd:COG4148   17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGevlQDsarGIFLPPHRRRIGYVFQEARLFPHLSVRG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  95 NVAFGLRmqKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLRE 174
Cdd:COG4148   97 NLLYGRK--RAPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEILP 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 175 QIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLLDAdkatqllqrpis 254
Cdd:COG4148  175 YLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPDLLPLAGGEEAGSVLEA------------ 242

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 545130686 255 sRIAIRPEAIELSR----TGELdaLVRSHSL-LGNVIRYRIEARGVEL 297
Cdd:COG4148  243 -TVAAHDPDYGLTRlalgGGRL--WVPRLDLpPGTRVRVRIRARDVSL 287
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 4-225 2.94e-66

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 211.07  E-value: 2.94e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSY---AGT-PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGL---TSVDSGKILLDGQDIVPLSPQK-- 74
Cdd:COG0444    2 LEVRNLKVYFptrRGVvKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLlppPGITSGEILFDGEDLLKLSEKElr 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  75 ----RHIGMVFQ-SY-ALFPNMTVEQNVAFGLRM-QKVNADDSHKRVQEVLQLVEL---KDLAGRYPHQMSGGQCQRVAL 144
Cdd:COG0444   82 kirgREIQMIFQdPMtSLNPVMTVGDQIAEPLRIhGGLSKAEARERAIELLERVGLpdpERRLDRYPHELSGGMRQRVMI 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 145 ARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTA 224
Cdd:COG0444  162 ARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELFEN 241


                 .
gi 545130686 225 P 225
Cdd:COG0444  242 P 242
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 5-206 2.79e-65

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 204.64  E-value: 2.79e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVD---SGKILLDGQDIVPLSPQKRHIGMVF 81
Cdd:COG4136    3 SLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVLLNGRRLTALPAEQRRIGILF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 QSYALFPNMTVEQNVAFGLRmQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:COG4136   83 QDDLLFPHLSVGENLAFALP-PTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPF 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 545130686 162 SALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFL 206
Cdd:COG4136  162 SKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDAPAAGRVLDL 206
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 4-221 1.18e-64

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 204.52  E-value: 1.18e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYA-GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK-----RHI 77
Cdd:COG3638    3 LELRNLSKRYPgGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRAlrrlrRRI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVFQSYALFPNMTVEQNVAFGL--RM-------QKVNADDsHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSL 148
Cdd:COG3638   83 GMIFQQFNLVPRLSVLTNVLAGRlgRTstwrsllGLFPPED-RERALEALERVGLADKAYQRADQLSGGQQQRVAIARAL 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545130686 149 VTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:COG3638  162 VQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGPPAEL 234
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 4-230 2.52e-64

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 204.20  E-value: 2.52e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    4 VSVQHLQKSYAGT--PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDivPLSPQK-----RH 76
Cdd:TIGR04520   1 IEVENVSFSYPESekPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLD--TLDEENlweirKK 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   77 IGMVFQSyalfP-----NMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTR 151
Cdd:TIGR04520  79 VGMVFQN----PdnqfvGATVEDDVAFGLENLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMR 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686  152 PRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALtMSDRIFLMNQGKIVQSGdaetlytAPVDVFA 230
Cdd:TIGR04520 155 PDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAV-LADRVIVMNKGKIVAEG-------TPREIFS 225
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 4-251 7.17e-64

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 203.45  E-value: 7.17e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    4 VSVQHLQKSYA-GTP----VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP-----LSPQ 73
Cdd:TIGR04521   1 IKLKNVSYIYQpGTPfekkALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAkkkkkLKDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   74 KRHIGMVFQ--SYALFPNmTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVEL-KDLAGRYPHQMSGGQCQRVALARSLVT 150
Cdd:TIGR04521  81 RKKVGLVFQfpEHQLFEE-TVYKDIAFGPKNLGLSEEEAEERVKEALELVGLdEEYLERSPFELSGGQMRRVAIAGVLAM 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  151 RPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGdaetlytAPVDVFA 230
Cdd:TIGR04521 160 EPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDG-------TPREVFS 232

                         250       260
                  ....*....|....*....|..
gi 545130686  231 AG-FIGNYNlLDADKATQLLQR 251
Cdd:TIGR04521 233 DVdELEKIG-LDVPEITELARK 253
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
4-225 9.00e-64

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 201.86  E-value: 9.00e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHI----GM 79
Cdd:PRK09493   2 IEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERLIrqeaGM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNMTVEQNVAFG-LRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLD 158
Cdd:PRK09493  82 VFQQFYLFPHLTALENVMFGpLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFD 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 159 EPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK09493 162 EPTSALDPELRHEVLKVMQDLAEE-GMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNP 227
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 4-225 1.30e-63

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 204.58  E-value: 1.30e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYA-GTPVFS----------DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP 72
Cdd:COG4608    8 LEVRDLKKHFPvRGGLFGrtvgvvkavdGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  73 QK-----RHIGMVFQ-SYA-LFPNMTVEQNVAFGLRMQKVNADDSHK-RVQEVLQLVELK-DLAGRYPHQMSGGQCQRVA 143
Cdd:COG4608   88 RElrplrRRMQMVFQdPYAsLNPRMTVGDIIAEPLRIHGLASKAERReRVAELLELVGLRpEHADRYPHEFSGGQRQRIG 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 144 LARSLVTRPRLLLLDEPLSALDARIRKhlreQI----RQIQRELGLTTIFVTHDqeeaLTM----SDRIFLMNQGKIVQS 215
Cdd:COG4608  168 IARALALNPKLIVCDEPVSALDVSIQA----QVlnllEDLQDELGLTYLFISHD----LSVvrhiSDRVAVMYLGKIVEI 239

                        250
                 ....*....|
gi 545130686 216 GDAETLYTAP 225
Cdd:COG4608  240 APRDELYARP 249
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 7-287 2.08e-60

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 196.56  E-value: 2.08e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   7 QHLQKSYAG----TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ-----KRHI 77
Cdd:PRK11153   5 KNISKVFPQggrtIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKelrkaRRQI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:PRK11153  85 GMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLLC 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 158 DEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGny 237
Cdd:PRK11153 165 DEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPKHPLTREFIQ-- 242

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 545130686 238 NLLDADKATQLLQRPISSRIAIRPEAIELSRTGE-LDAlvrshSLLGNVIR 287
Cdd:PRK11153 243 STLHLDLPEDYLARLQAEPTTGSGPLLRLEFTGEsVDA-----PLLSETAR 288
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-226 3.17e-60

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 193.00  E-value: 3.17e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdivPLSPQKRHIGMV 80
Cdd:COG1121    4 MPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGK---PPRRARRRIGYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYAL---FPnMTVEQNVAFGLR-----MQKVNADDsHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRP 152
Cdd:COG1121   81 PQRAEVdwdFP-ITVRDVVLMGRYgrrglFRRPSRAD-REAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDP 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 153 RLLLLDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGkIVQSGDAETLYTAPV 226
Cdd:COG1121  159 DLLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLLLNRG-LVAHGPPEEVLTPEN 230
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 4-221 1.54e-59

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 190.47  E-value: 1.54e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSV-----DSGKILLDGQDIVPLSPQ----K 74
Cdd:cd03260    1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLLDGKDIYDLDVDvlelR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  75 RHIGMVFQSYALFPnMTVEQNVAFGLRMQKV-NADDSHKRVQEVLQLVELKDLAGR--YPHQMSGGQCQRVALARSLVTR 151
Cdd:cd03260   81 RRVGMVFQKPNPFP-GSIYDNVAYGLRLHGIkLKEELDERVEEALRKAALWDEVKDrlHALGLSGGQQQRLCLARALANE 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 152 PRLLLLDEPLSALDARIRKHLREQIRQIQRElgLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:cd03260  160 PEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 4-212 3.08e-59

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 187.99  E-value: 3.08e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ-KRHIGMVFQ 82
Cdd:cd03230    1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEvKRRIGYLPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SYALFPNMTVEQNVafglrmqkvnaddshkrvqevlqlvelkdlagryphQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:cd03230   81 EPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDPELLILDEPTS 124

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 545130686 163 ALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKI 212
Cdd:cd03230  125 GLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 6-221 3.28e-59

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 190.45  E-value: 3.28e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ-KRHIGMVFQSY 84
Cdd:COG4555    4 VENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREaRRQIGVLPDER 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  85 ALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSAL 164
Cdd:COG4555   84 GLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNGL 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 165 DARIRKHLREQIRQIqRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:COG4555  164 DVMARRLLREILRAL-KKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDEL 219
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 21-210 9.24e-59

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 188.83  E-value: 9.24e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRhigMVFQSYALFPNMTVEQNVAFGL 100
Cdd:TIGR01184   3 GVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRM---VVFQNYSLLPWLTVRENIALAV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  101 RMQKVNADDSHKR--VQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQ 178
Cdd:TIGR01184  80 DRVLPDLSKSERRaiVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEELMQ 159

                         170       180       190
                  ....*....|....*....|....*....|..
gi 545130686  179 IQRELGLTTIFVTHDQEEALTMSDRIFLMNQG 210
Cdd:TIGR01184 160 IWEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
5-212 9.52e-59

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 188.10  E-value: 9.52e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMVFQ 82
Cdd:COG4619    2 ELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEwrRQVAYVPQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SYALFPNmTVEQNVAFGLRMQKVNADDshKRVQEVLQLVEL-KDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:COG4619   82 EPALWGG-TVRDNLPFPFQLRERKFDR--ERALELLERLGLpPDILDKPVERLSGGERQRLALIRALLLQPDVLLLDEPT 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 545130686 162 SALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKI 212
Cdd:COG4619  159 SALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 21-225 3.58e-58

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 195.67  E-value: 3.58e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSvDSGKILLDGQDIVPLS-----PQKRHIGMVFQS-YA-LFPNMTVE 93
Cdd:COG4172  304 GVSLTLRRGETLGLVGESGSGKSTLGLALLRLIP-SEGEIRFDGQDLDGLSrralrPLRRRMQVVFQDpFGsLSPRMTVG 382

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  94 QNVAFGLRMQKV--NADDSHKRVQEVLQLVELK-DLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRK 170
Cdd:COG4172  383 QIIAEGLRVHGPglSAAERRARVAEALEEVGLDpAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQA 462

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 171 HLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:COG4172  463 QILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAP 517
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 5-216 1.20e-57

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 184.18  E-value: 1.20e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMVFQ 82
Cdd:cd03214    1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKElaRKIAYVPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 syalfpnmtveqnvafglrmqkvnaddshkrvqeVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:cd03214   81 ----------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTS 126

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 545130686 163 ALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03214  127 HLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 4-219 8.23e-57

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 183.79  E-value: 8.23e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGT----PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR---- 75
Cdd:COG4181    9 IELRGLTKTVGTGagelTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARarlr 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  76 --HIGMVFQSYALFPNMTVEQNVAfgLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPR 153
Cdd:COG4181   89 arHVGFVFQSFQLLPTLTALENVM--LPLELAGRRDARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEPA 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 154 LLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALtMSDRIFLMNQGKIVQSGDAE 219
Cdd:COG4181  167 ILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAA-RCDRVLRLRAGRLVEDTAAT 231
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 5-221 2.22e-56

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 182.25  E-value: 2.22e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR---HIGMVF 81
Cdd:cd03224    2 EVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERaraGIGYVP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 QSYALFPNMTVEQNVAFGLRMQKvnADDSHKRVQEVLQLV-ELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:cd03224   82 EGRRIFPELTVEENLLLGAYARR--RAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEP 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686 161 LSALDARIRKHLREQIRQIqRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:cd03224  160 SEGLAPKIVEEIFEAIREL-RDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 6-227 3.87e-56

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 182.38  E-value: 3.87e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYA-GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP-----QKRHIGM 79
Cdd:cd03256    3 VENLSKTYPnGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGkalrqLRRQIGM 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNMTVEQNVAFGL--RMQKVNA-----DDSHKRVQ-EVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTR 151
Cdd:cd03256   83 IFQQFNLIERLSVLENVLSGRlgRRSTWRSlfglfPKEEKQRAlAALERVGLLDKAYQRADQLSGGQQQRVAIARALMQQ 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 152 PRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVD 227
Cdd:cd03256  163 PKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAELTDEVLD 238
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 4-221 2.00e-55

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 191.59  E-value: 2.00e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAG--TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGM 79
Cdd:COG2274  474 IELENVSFRYPGdsPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASlrRQIGV 553

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFpNMTVEQNVAFGlrmqkvNADDSHKRVQEVLQLVELKDLAGRYPHQM-----------SGGQCQRVALARSL 148
Cdd:COG2274  554 VLQDVFLF-SGTIRENITLG------DPDATDEEIIEAARLAGLHDFIEALPMGYdtvvgeggsnlSGGQRQRLAIARAL 626

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545130686 149 VTRPRLLLLDEPLSALDARIRKHLREQIRQIQRelGLTTIFVTHDqEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:COG2274  627 LRNPRILILDEATSALDAETEAIILENLRRLLK--GRTVIIIAHR-LSTIRLADRIIVLDKGRIVEDGTHEEL 696
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 5-219 3.39e-55

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 179.56  E-value: 3.39e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRH---IGMVF 81
Cdd:cd03219    2 EVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIArlgIGRTF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 QSYALFPNMTVEQNVAFGLRMQKVNA----------DDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTR 151
Cdd:cd03219   82 QIPRLFPELTVLENVMVAAQARTGSGlllararreeREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATD 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 152 PRLLLLDEPLSALDARIRKHLREQIRQIqRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAE 219
Cdd:cd03219  162 PKLLLLDEPAAGLNPEETEELAELIREL-RERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPD 228
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
1-225 3.55e-55

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 179.82  E-value: 3.55e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSfVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI---VPLSPQ---- 73
Cdd:COG4161    1 MS-IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFdfsQKPSEKairl 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  74 -KRHIGMVFQSYALFPNMTVEQN-VAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTR 151
Cdd:COG4161   80 lRQKVGMVFQQYNLWPHLTVMENlIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMME 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 152 PRLLLLDEPLSALDARIRKHLREQIRQIQrELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAEtLYTAP 225
Cdd:COG4161  160 PQVLLFDEPTAALDPEITAQVVEIIRELS-QTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDAS-HFTQP 231
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 1-221 4.41e-55

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 179.41  E-value: 4.41e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR---HI 77
Cdd:COG0410    1 MPMLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIarlGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVFQSYALFPNMTVEQNVAFGLRMQKvNADDSHKRVQEVLQLV-ELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:COG0410   81 GYVPEGRRIFPSLTVEENLLLGAYARR-DRAEVRADLERVYELFpRLKERRRQRAGTLSGGEQQMLAIGRALMSRPKLLL 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:COG0410  160 LDEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAEL 223
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
6-214 1.92e-54

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 178.35  E-value: 1.92e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKrhiGMVFQSYA 85
Cdd:PRK11248   4 ISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER---GVVFQNEG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  86 LFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD 165
Cdd:PRK11248  81 LLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 545130686 166 ARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLM--NQGKIVQ 214
Cdd:PRK11248 161 AFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLspGPGRVVE 211
heterocyst_DevA TIGR02982
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ...
 4-213 2.29e-54

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.


Pssm-ID: 274374 [Multi-domain]  Cd Length: 220  Bit Score: 177.13  E-value: 2.29e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    4 VSVQHLQKSYaGT-----PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK---- 74
Cdd:TIGR02982   2 ISIRNLNHYY-GHgslrkQVLFDINLEINPGEIVILTGPSGSGKTTLLTLIGGLRSVQEGSLKVLGQELHGASKKQlvql 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   75 -RHIGMVFQSYALFPNMTVEQNVAFGLRMQ-KVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRP 152
Cdd:TIGR02982  81 rRRIGYIFQAHNLLGFLTARQNVQMALELQpNLSYQEARERARAMLEAVGLGDHLNYYPHNLSGGQKQRVAIARALVHHP 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686  153 RLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQeEALTMSDRIFLMNQGKIV 213
Cdd:TIGR02982 161 KLVLADEPTAALDSKSGRDVVELMQKLAKEQGCTILMVTHDN-RILDVADRILQMEDGKLL 220
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
2-232 4.88e-54

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 178.29  E-value: 4.88e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   2 SFVSVQHLQKSY--AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdivPLSPQ-----K 74
Cdd:PRK13635   4 EIIRVEHISFRYpdAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGM---VLSEEtvwdvR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  75 RHIGMVFQSY-ALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPR 153
Cdd:PRK13635  81 RQVGMVFQNPdNQFVGATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPD 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 154 LLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTmSDRIFLMNQGKIVQSGdaetlytAPVDVFAAG 232
Cdd:PRK13635 161 IIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEG-------TPEEIFKSG 231
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 1-225 5.52e-54

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 176.74  E-value: 5.52e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSfVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQ-----------DIVP 69
Cdd:PRK11124   1 MS-IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNhfdfsktpsdkAIRE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  70 LspqKRHIGMVFQSYALFPNMTVEQN-VAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSL 148
Cdd:PRK11124  80 L---RRNVGMVFQQYNLWPHLTVQQNlIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARAL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 149 VTRPRLLLLDEPLSALDARIRKhlreQIRQIQREL---GLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAeTLYTAP 225
Cdd:PRK11124 157 MMEPQVLLFDEPTAALDPEITA----QIVSIIRELaetGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDA-SCFTQP 231
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 6-227 6.50e-54

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 176.72  E-value: 6.50e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    6 VQHLQKSY-AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK-----RHIGM 79
Cdd:TIGR02315   4 VENLSKVYpNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKlrklrRRIGM 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   80 VFQSYALFPNMTVEQNVAFGlRMQKVNA---------DDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVT 150
Cdd:TIGR02315  84 IFQHYNLIERLTVLENVLHG-RLGYKPTwrsllgrfsEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIARALAQ 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686  151 RPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVD 227
Cdd:TIGR02315 163 QPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSELDDEVLR 239
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 6-212 1.40e-53

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 176.41  E-value: 1.40e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKiLLDGQdiVPLSPQKRHIGMVFQSYA 85
Cdd:PRK11247  15 LNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGE-LLAGT--APLAEAREDTRLMFQDAR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  86 LFPNMTVEQNVAFGLRmqkvnaDDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD 165
Cdd:PRK11247  92 LLPWKKVIDNVGLGLK------GQWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALD 165

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 545130686 166 ARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKI 212
Cdd:PRK11247 166 ALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 5-216 2.10e-53

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 174.26  E-value: 2.10e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdivPLSPQKRHIGMVFQSY 84
Cdd:cd03235    1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGK---PLEKERKRIGYVPQRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  85 AL---FPnMTVEQNVAFGLR-----MQKVNADDShKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:cd03235   78 SIdrdFP-ISVRDVVLMGLYghkglFRRLSKADK-AKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLL 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNqGKIVQSG 216
Cdd:cd03235  156 LDEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLLN-RTVVASG 213
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 21-226 2.72e-53

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 178.38  E-value: 2.72e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI------VPLSPQKRHIGMVFQSYALFPNMTVEQ 94
Cdd:TIGR02142  15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLfdsrkgIFLPPEKRRIGYVFQEARLFPHLSVRG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   95 NVAFGlrMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLRE 174
Cdd:TIGR02142  95 NLRYG--MKRARPSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILP 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 545130686  175 QIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPV 226
Cdd:TIGR02142 173 YLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPD 224
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 4-197 3.33e-53

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 173.43  E-value: 3.33e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ-KRHIGMVFQ 82
Cdd:COG4133    3 LEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDyRRRLAYLGH 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SYALFPNMTVEQNVAFGLRMQKVNADDShkRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:COG4133   83 ADGLKPELTVRENLRFWAALYGLRADRE--AIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFT 160

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 545130686 163 ALDARIRKHLREQIRQiQRELGLTTIFVTHDQEEA 197
Cdd:COG4133  161 ALDAAGVALLAELIAA-HLARGGAVLLTTHQPLEL 194
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
25-221 5.66e-53

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 174.00  E-value: 5.66e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  25 EVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQSYALFPNMTVEQNVAFGLRMQ- 103
Cdd:PRK10771  21 TVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGl 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 104 KVNADdSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQREL 183
Cdd:PRK10771 101 KLNAA-QREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQVCQER 179

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 545130686 184 GLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:PRK10771 180 QLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDEL 217
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 4-227 1.51e-52

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 173.68  E-value: 1.51e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRC-------IAGLTSvdSGKILLDGQDIvpLSPQ--- 73
Cdd:COG1117   12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRClnrmndlIPGARV--EGEILLDGEDI--YDPDvdv 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  74 ---KRHIGMVFQSYALFPnMTVEQNVAFGLRMQKV-NADDSHKRVQEVLQLV----ELKDLAGRYPHQMSGGQCQRVALA 145
Cdd:COG1117   88 velRRRVGMVFQKPNPFP-KSIYDNVAYGLRLHGIkSKSELDEIVEESLRKAalwdEVKDRLKKSALGLSGGQQQRLCIA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 146 RSLVTRPRLLLLDEPLSALD----ARIrkhlREQIRQIQRElgLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:COG1117  167 RALAVEPEVLLMDEPTSALDpistAKI----EELILELKKD--YTIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQI 240


                 ....*.
gi 545130686 222 YTAPVD 227
Cdd:COG1117  241 FTNPKD 246
cbiO PRK13637
energy-coupling factor transporter ATPase;
1-229 1.92e-52

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 174.47  E-value: 1.92e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSfVSVQHLQKSY-AGTP----VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI----VPLS 71
Cdd:PRK13637   1 MS-IKIENLTHIYmEGTPfekkALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDItdkkVKLS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  72 PQKRHIGMVFQ--SYALFPNmTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELK--DLAGRYPHQMSGGQCQRVALARS 147
Cdd:PRK13637  80 DIRKKVGLVFQypEYQLFEE-TIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLDyeDYKDKSPFELSGGQKRRVAIAGV 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 148 LVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGdaetlytAPVD 227
Cdd:PRK13637 159 VAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQG-------TPRE 231


                 ..
gi 545130686 228 VF 229
Cdd:PRK13637 232 VF 233
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 8-211 5.27e-52

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 170.89  E-value: 5.27e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    8 HLQKSY-AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLS----PQ-KRHIGMVF 81
Cdd:TIGR02673   6 NVSKAYpGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRgrqlPLlRRRIGVVF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   82 QSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:TIGR02673  86 QDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLADEPT 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 545130686  162 SALDArirkHLREQIRQIQREL---GLTTIFVTHDQEEALTMSDRIFLMNQGK 211
Cdd:TIGR02673 166 GNLDP----DLSERILDLLKRLnkrGTTVIVATHDLSLVDRVAHRVIILDDGR 214
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 12-216 5.61e-52

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 170.75  E-value: 5.61e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  12 SYAGTPVfsDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQSYALFPNMT 91
Cdd:cd03298    9 SYGEQPM--HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRPVSMLFQENNLFAHLT 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  92 VEQNVAFGLRMQ-KVNADDsHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRK 170
Cdd:cd03298   87 VEQNVGLGLSPGlKLTAED-RQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRA 165

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 545130686 171 HLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03298  166 EMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-213 6.20e-52

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 172.19  E-value: 6.20e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKS-YAGTP----VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR--H 76
Cdd:COG1101    2 LELKNLSKTfNPGTVnekrALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRakY 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  77 IGMVFQSYAL--FPNMTVEQNVA--------FGLRMQKVNADdsHKRVQEVLQLVE------LKDLAGryphQMSGGQCQ 140
Cdd:COG1101   82 IGRVFQDPMMgtAPSMTIEENLAlayrrgkrRGLRRGLTKKR--RELFRELLATLGlglenrLDTKVG----LLSGGQRQ 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545130686 141 RVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIV 213
Cdd:COG1101  156 ALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGRII 228
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 4-221 1.34e-51

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 169.86  E-value: 1.34e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ-KRHIGMVFQ 82
Cdd:cd03265    1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREvRRRIGIVFQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:cd03265   81 DLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTI 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 163 ALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:cd03265  161 GLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 1-225 1.41e-51

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 171.09  E-value: 1.41e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI---VPLSPQKR-- 75
Cdd:PRK11264   1 MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIdtaRSLSQQKGli 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  76 -----HIGMVFQSYALFPNMTVEQNVAFG-LRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLV 149
Cdd:PRK11264  81 rqlrqHVGFVFQNFNLFPHRTVLENIIEGpVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 150 TRPRLLLLDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK11264 161 MRPEVILFDEPTSALDPELVGEVLNTIRQLAQE-KRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADP 235
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 6-204 4.19e-51

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 168.18  E-value: 4.19e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    6 VQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRH------IGM 79
Cdd:TIGR03608   1 LKNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASkfrrekLGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   80 VFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDE 159
Cdd:TIGR03608  81 LFQNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADE 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 545130686  160 PLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEAlTMSDRI 204
Cdd:TIGR03608 161 PTGSLDPKNRDEVLDLLLELNDE-GKTIIIVTHDPEVA-KQADRV 203
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 4-226 1.08e-50

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 168.11  E-value: 1.08e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR-HIGMVF- 81
Cdd:cd03218    1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRaRLGIGYl 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 -QSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:cd03218   81 pQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEP 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 161 LSALDARIRKHLREQIRQI-QRELGlttIFVT-HDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPV 226
Cdd:cd03218  161 FAGVDPIAVQDIQKIIKILkDRGIG---VLITdHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANEL 225
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 4-216 2.65e-50

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 166.24  E-value: 2.65e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQS 83
Cdd:cd03268    1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEALRRIGALIEA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YALFPNMTVEQNVAFGLRMQKVnaddSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:cd03268   81 PGFYPNLTARENLRLLARLLGI----RKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNG 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 545130686 164 LDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03268  157 LDPDGIKELRELILSLRDQ-GITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 19-162 3.90e-50

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 163.97  E-value: 3.90e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   19 FSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFPNMTVEQNV 96
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKslRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   97 AFGLRMQKVNADDSHKRVQEVLQLVELKDLA----GRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLAdrpvGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 1-222 8.65e-50

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 165.97  E-value: 8.65e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRH---I 77
Cdd:COG1137    1 MMTLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKRArlgI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:COG1137   81 GYLPQEASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFILL 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545130686 158 DEPLSALD----ARIRK---HLREqirqiqRELGlttIFVT-HDQEEALTMSDRIFLMNQGKIVQSGDAETLY 222
Cdd:COG1137  161 DEPFAGVDpiavADIQKiirHLKE------RGIG---VLITdHNVRETLGICDRAYIISEGKVLAEGTPEEIL 224
ectoine_ehuA TIGR03005
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ...
 4-225 3.76e-49

ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding protein of a conserved four gene ABC transporter operon found next to ectoine unilization operons and ectoine biosynthesis operons. Ectoine is a compatible solute that protects enzymes from high osmolarity. It is released by some species in response to hypoosmotic shock, and it is taken up by a number of bacteria as a compatible solute or for consumption. This family shows strong sequence similiarity to a number of amino acid ABC transporter ATP-binding proteins.


Pssm-ID: 132050 [Multi-domain]  Cd Length: 252  Bit Score: 164.62  E-value: 3.76e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIV-------PLSPQ--- 73
Cdd:TIGR03005   1 VRFSDVTKRFGILTVLDGLNFSVAAGEKVALIGPSGSGKSTILRILMTLEPIDEGQIQVEGEQLYhmpgrngPLVPAdek 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   74 -----KRHIGMVFQSYALFPNMTVEQNVAFG-LRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARS 147
Cdd:TIGR03005  81 hlrqmRNKIGMVFQSFNLFPHKTVLDNVTEApVLVLGMARAEAEKRAMELLDMVGLADKADHMPAQLSGGQQQRVAIARA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686  148 LVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:TIGR03005 161 LAMRPKVMLFDEVTSALDPELVGEVLNVIRRLASEHDLTMLLVTHEMGFAREFADRVCFFDKGRIVEQGKPDEIFRQP 238
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 4-222 7.69e-49

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 171.48  E-value: 7.69e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYA-GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMV 80
Cdd:COG4988  337 IELEDVSFSYPgGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPAswRRQIAWV 416

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPnMTVEQNVAFGlrmqKVNADDShkRVQEVLQLVELKDLAGRYPHQM-----------SGGQCQRVALARSLV 149
Cdd:COG4988  417 PQNPYLFA-GTIRENLRLG----RPDASDE--ELEAALEAAGLDEFVAALPDGLdtplgeggrglSGGQAQRLALARALL 489

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545130686 150 TRPRLLLLDEPLSALDARIRKHLREQIRQIQRelGLTTIFVTHDqEEALTMSDRIFLMNQGKIVQSGDAETLY 222
Cdd:COG4988  490 RDAPLLLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITHR-LALLAQADRILVLDDGRIVEQGTHEELL 559
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 4-216 1.86e-48

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 161.59  E-value: 1.86e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVtLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDiVPLSPQK--RHIGMVF 81
Cdd:cd03264    1 LQLENLTKRYGKKRALDGVSLTLGPGMYG-LLGPNGAGKTTLMRILATLTPPSSGTIRIDGQD-VLKQPQKlrRRIGYLP 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 QSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:cd03264   79 QEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPT 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 162 SALD--ARIRkhlreqIRQIQRELGLTTIFV--THDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03264  159 AGLDpeERIR------FRNLLSELGEDRIVIlsTHIVEDVESLCNQVAVLNKGKLVFEG 211
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 1-225 2.16e-48

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 169.87  E-value: 2.16e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAG----TPVFSDINCEVAKGEFVTLLGPSGCGKS----TLLRCIAGLTSVDSGKILLDGQDIVPLSP 72
Cdd:COG4172    4 MPLLSVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLGLSE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  73 QK------RHIGMVFQ--SYALFPNMTVEQNVAFGLRM-QKVNADDSHKRVQEVLQLVELKDLAGR---YPHQMSGGQCQ 140
Cdd:COG4172   84 RElrrirgNRIAMIFQepMTSLNPLHTIGKQIAEVLRLhRGLSGAAARARALELLERVGIPDPERRldaYPHQLSGGQRQ 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 141 RVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDqeeaLT----MSDRIFLMNQGKIVQSG 216
Cdd:COG4172  164 RVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHD----LGvvrrFADRVAVMRQGEIVEQG 239


                 ....*....
gi 545130686 217 DAETLYTAP 225
Cdd:COG4172  240 PTAELFAAP 248
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 1-224 3.24e-48

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 162.18  E-value: 3.24e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGL---TSVDSGKIL---LDGQDIVPLspqK 74
Cdd:COG1119    1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDlppTYGNDVRLFgerRGGEDVWEL---R 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  75 RHIGMVfqSYALF----PNMTVEQNVAFGL-----RMQKVNADDsHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALA 145
Cdd:COG1119   78 KRIGLV--SPALQlrfpRDETVLDVVLSGFfdsigLYREPTDEQ-RERARELLELLGLAHLADRPFGTLSQGEQRRVLIA 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 146 RSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTA 224
Cdd:COG1119  155 RALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEVLTS 233
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 11-212 3.92e-48

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 161.04  E-value: 3.92e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  11 KSY-AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK-----RHIGMVFQSY 84
Cdd:cd03292    8 KTYpNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAipylrRKIGVVFQDF 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  85 ALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSAL 164
Cdd:cd03292   88 RLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNL 167

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 545130686 165 DARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKI 212
Cdd:cd03292  168 DPDTTWEIMNLLKKINKA-GTTVVVATHAKELVDTTRHRVIALERGKL 214
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 4-216 4.61e-48

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 160.75  E-value: 4.61e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAG--TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ-KRHIGMV 80
Cdd:cd03263    1 LQIRNLTKTYKKgtKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAaRQSLGYC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:cd03263   81 PQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEP 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 161 LSALDARIRKHLREQIRQIQRelGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03263  161 TSGLDPASRRAIWDLILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIG 214
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 5-211 5.67e-48

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 158.56  E-value: 5.67e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGMVFQ 82
Cdd:cd00267    1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIakLPLEELRRRIGYVPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 syalfpnmtveqnvafglrmqkvnaddshkrvqevlqlvelkdlagryphqMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:cd00267   81 ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTS 109

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 545130686 163 ALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGK 211
Cdd:cd00267  110 GLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
cbiO PRK13650
energy-coupling factor transporter ATPase;
17-222 6.84e-48

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 162.21  E-value: 6.84e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP--LSPQKRHIGMVFQSY-ALFPNMTVE 93
Cdd:PRK13650  21 YTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEenVWDIRHKIGMVFQNPdNQFVGATVE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  94 QNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLR 173
Cdd:PRK13650 101 DDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELI 180

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 545130686 174 EQIRQIQRELGLTTIFVTHDQEEaLTMSDRIFLMNQGKIVQSGDAETLY 222
Cdd:PRK13650 181 KTIKGIRDDYQMTVISITHDLDE-VALSDRVLVMKNGQVESTSTPRELF 228
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 5-231 1.36e-47

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 160.71  E-value: 1.36e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMVFQ 82
Cdd:PRK13548   4 EARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAElaRRRAVLPQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SYAL-FPnMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLV------TRPRLL 155
Cdd:PRK13548  84 HSSLsFP-FTVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGPPRWL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 156 LLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG------DAETL---YTAPV 226
Cdd:PRK13548 163 LLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGtpaevlTPETLrrvYGADV 242


                 ....*
gi 545130686 227 DVFAA 231
Cdd:PRK13548 243 LVQPH 247
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 21-225 1.43e-47

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 162.95  E-value: 1.43e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRH-----IGMVFQS--YALFPNMTVE 93
Cdd:PRK15079  39 GVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRavrsdIQMIFQDplASLNPRMTIG 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  94 QNVAFGLRM--QKVNADDSHKRVQEVLQLVEL-KDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRK 170
Cdd:PRK15079 119 EIIAEPLRTyhPKLSRQEVKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQA 198

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 171 HLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK15079 199 QVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNP 253
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 23-217 1.70e-47

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 159.26  E-value: 1.70e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   23 NCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQSYALFPNMTVEQNVAFGLRM 102
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAPYQRPVSMLFQENNLFAHLTVRQNIGLGLHP 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  103 Q-KVNADDSHKrVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQR 181
Cdd:TIGR01277  98 GlKLNAEQQEK-VVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQLCS 176

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 545130686  182 ELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGD 217
Cdd:TIGR01277 177 ERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVSD 212
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
5-226 7.74e-47

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 158.74  E-value: 7.74e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMVFQ 82
Cdd:COG4559    3 EAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWElaRRRAVLPQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SYAL-FPnMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLV-------TRPRL 154
Cdd:COG4559   83 HSSLaFP-FTVEEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAqlwepvdGGPRW 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 155 LLLDEPLSALDarirkhLREQIR--QIQREL---GLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPV 226
Cdd:COG4559  162 LFLDEPTSALD------LAHQHAvlRLARQLarrGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEEVLTDEL 232
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
12-216 8.21e-47

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 166.49  E-value: 8.21e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  12 SY-AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMVFQSYALFp 88
Cdd:COG1132  348 SYpGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESlrRQIGVVPQDTFLF- 426

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  89 NMTVEQNVAFGlrmqKVNADDshKRVQEVLQLVELKDLAGRYPHQM-----------SGGQCQRVALARSLVTRPRLLLL 157
Cdd:COG1132  427 SGTIRENIRYG----RPDATD--EEVEEAAKAAQAHEFIEALPDGYdtvvgergvnlSGGQRQRIAIARALLKDPPILIL 500

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 158 DEPLSALDARIRKHLREQIRQIQRelGLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:COG1132  501 DEATSALDTETEALIQEALERLMK--GRTTIVIAH-RLSTIRNADRILVLDDGRIVEQG 556
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 4-211 1.09e-46

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 155.62  E-value: 1.09e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGT--PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGM 79
Cdd:cd03228    1 IEFKNVSFSYPGRpkPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESlrKNIAY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFpNMTVEQNVafglrmqkvnaddshkrvqevlqlvelkdlagryphqMSGGQCQRVALARSLVTRPRLLLLDE 159
Cdd:cd03228   81 VPQDPFLF-SGTIRENI-------------------------------------LSGGQRQRIAIARALLRDPPILILDE 122

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 545130686 160 PLSALDARIRKHLREQIRQIQRelGLTTIFVTHDqEEALTMSDRIFLMNQGK 211
Cdd:cd03228  123 ATSALDPETEALILEALRALAK--GKTVIVIAHR-LSTIRDADRIIVLDDGR 171
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
3-221 8.44e-46

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 162.11  E-value: 8.44e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   3 FVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP---QKRHIGM 79
Cdd:COG1129    4 LLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPrdaQAAGIAI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNMTVEQNVAFG---LRMQKVNADDSHKRVQEVLQLVEL----KDLAGRYphqmSGGQCQRVALARSLVTRP 152
Cdd:COG1129   84 IHQELNLVPNLSVAENIFLGrepRRGGLIDWRAMRRRARELLARLGLdidpDTPVGDL----SVAQQQLVEIARALSRDA 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 153 RLLLLDEPLSALDARIRKHLREQIRQIqRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:COG1129  160 RVLILDEPTASLTEREVERLFRIIRRL-KAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVAEL 227
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
4-225 1.26e-45

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 155.73  E-value: 1.26e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI----------VPLSPQ 73
Cdd:COG4598    9 LEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIrlkpdrdgelVPADRR 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  74 K-----RHIGMVFQSYALFPNMTVEQNVAFG-LRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARS 147
Cdd:COG4598   89 QlqrirTRLGMVFQSFNLWSHMTVLENVIEApVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAAIARA 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 148 LVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:COG4598  169 LAMEPEVMLFDEPTSALDPELVGEVLKVMRDLAEE-GRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGNP 245
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 4-229 4.27e-45

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 154.09  E-value: 4.27e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMVF 81
Cdd:COG4604    2 IEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRElaKRLAILR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 QSYALFPNMTVEQNVAFGlRMQ----KVNADDsHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:COG4604   82 QENHINSRLTVRELVAFG-RFPyskgRLTAED-REIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVLL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 158 DEPLSALDArirKHLRE---QIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPV--DVF 229
Cdd:COG4604  160 DEPLNNLDM---KHSVQmmkLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEIITPEVlsDIY 233
LolD_lipo_ex TIGR02211
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...
 9-213 5.00e-45

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 131266 [Multi-domain]  Cd Length: 221  Bit Score: 152.89  E-value: 5.00e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    9 LQKSYA----GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR------HIG 78
Cdd:TIGR02211   7 LGKRYQegklDTRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGQSLSKLSSNERaklrnkKLG 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   79 MVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLD 158
Cdd:TIGR02211  87 FIYQFHHLLPDFTALENVAMPLLIGKKSVKEAKERAYEMLEKVGLEHRINHRPSELSGGERQRVAIARALVNQPSLVLAD 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 545130686  159 EPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMsDRIFLMNQGKIV 213
Cdd:TIGR02211 167 EPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLELAKKL-DRVLEMKDGQLF 220
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 4-216 5.27e-45

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 152.91  E-value: 5.27e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSY----AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPlSPQ--KRHI 77
Cdd:cd03266    2 ITADALTKRFrdvkKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVK-EPAeaRRRL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:cd03266   81 GFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLL 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 158 DEPLSALDARIRKHLREQIRQiQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03266  161 DEPTTGLDVMATRALREFIRQ-LRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 5-221 8.51e-45

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 152.68  E-value: 8.51e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR---HIGMVF 81
Cdd:TIGR03410   2 EVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERaraGIAYVP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   82 QSYALFPNMTVEQNVAFGLRMQKvnaDDSHKRVQEVLQLVE-LKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:TIGR03410  82 QGREIFPRLTVEENLLTGLAALP---RRSRKIPDEIYELFPvLKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEP 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686  161 LSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:TIGR03410 159 TEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL 219
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
21-261 5.64e-44

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 155.19  E-value: 5.64e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP------QKRHIGMVFQSYALFPNMTVEQ 94
Cdd:PRK10070  46 DASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDaelrevRRKKIAMVFQSFALMPHMTVLD 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  95 NVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLRE 174
Cdd:PRK10070 126 NTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQD 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 175 QIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFIGNYNLLDADKATQLLQRPIS 254
Cdd:PRK10070 206 ELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDISQVFSAKDIARRTPN 285


                 ....*..
gi 545130686 255 SRIAIRP 261
Cdd:PRK10070 286 GLIRKTP 292
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 4-221 6.02e-44

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 158.39  E-value: 6.02e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSY--AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGM 79
Cdd:COG4987  334 LELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDlrRRIAV 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFpNMTVEQNvafgLRMQKVNADDShkRVQEVLQLVELKDLAGRYPH-----------QMSGGQCQRVALARSL 148
Cdd:COG4987  414 VPQRPHLF-DTTLREN----LRLARPDATDE--ELWAALERVGLGDWLAALPDgldtwlgeggrRLSGGERRRLALARAL 486

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545130686 149 VTRPRLLLLDEPLSALDARIRKHLREQIRQIQRelGLTTIFVTHDQEEALTMsDRIFLMNQGKIVQSGDAETL 221
Cdd:COG4987  487 LRDAPILLLDEPTEGLDAATEQALLADLLEALA--GRTVLLITHRLAGLERM-DRILVLEDGRIVEQGTHEEL 556
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 4-216 1.96e-43

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 148.58  E-value: 1.96e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdivPLSPQKRH-IGMVFQ 82
Cdd:cd03269    1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGK---PLDIAARNrIGYLPE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:cd03269   78 ERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFS 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 545130686 163 ALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03269  158 GLDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 4-229 1.99e-43

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 150.53  E-value: 1.99e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAG--TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP--LSPQKRHIGM 79
Cdd:PRK13632   8 IKVENVSFSYPNseNNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKenLKEIRKKIGI 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSY-ALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLD 158
Cdd:PRK13632  88 IFQNPdNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFD 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686 159 EPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALtMSDRIFLMNQGKIVQSGDaetlytaPVDVF 229
Cdd:PRK13632 168 ESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLIAQGK-------PKEIL 230
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 4-251 2.11e-43

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 150.94  E-value: 2.11e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSY-AGTP----VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP------LSP 72
Cdd:PRK13634   3 ITFQKVEHRYqYKTPferrALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAgkknkkLKP 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  73 QKRHIGMVFQsyalFPNM-----TVEQNVAFGLRMQKVNADDSHKRVQEVLQLVEL-KDLAGRYPHQMSGGQCQRVALAR 146
Cdd:PRK13634  83 LRKKVGIVFQ----FPEHqlfeeTVEKDICFGPMNFGVSEEDAKQKAREMIELVGLpEELLARSPFELSGGQMRRVAIAG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 147 SLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPV 226
Cdd:PRK13634 159 VLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPD 238

                        250       260
                 ....*....|....*....|....*
gi 545130686 227 DVFAAGfignynlLDADKATQLLQR 251
Cdd:PRK13634 239 ELEAIG-------LDLPETVKFKRA 256
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 2-223 7.70e-43

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 148.80  E-value: 7.70e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    2 SFVSVQHLQKSYAGT---------PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP 72
Cdd:TIGR02769   1 SLLEVRDVTHTYRTGglfgakqraPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   73 Q-----KRHIGMVFQ-SYALF-PNMTVEQNVAFGLR-MQKVNADDSHKRVQEVLQLVELK-DLAGRYPHQMSGGQCQRVA 143
Cdd:TIGR02769  81 KqrrafRRDVQLVFQdSPSAVnPRMTVRQIIGEPLRhLTSLDESEQKARIAELLDMVGLRsEDADKLPRQLSGGQLQRIN 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  144 LARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYT 223
Cdd:TIGR02769 161 IARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQLLS 240
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 4-213 1.90e-42

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 144.49  E-value: 1.90e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP---QKRHIGMV 80
Cdd:cd03216    1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPrdaRRAGIAMV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 fqsyalfpnmtveqnvafglrmqkvnaddshkrvqevlqlvelkdlagrypHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:cd03216   81 ---------------------------------------------------YQLSVGERQMVEIARALARNARLLILDEP 109

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 545130686 161 LSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIV 213
Cdd:cd03216  110 TAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 21-222 4.70e-42

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 146.82  E-value: 4.70e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP--LSPQKRHIGMVFQS-YALFPNMTVEQNVA 97
Cdd:PRK13648  27 DVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDdnFEKLRKHIGIVFQNpDNQFVGSIVKYDVA 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  98 FGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIR 177
Cdd:PRK13648 107 FGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVR 186

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 545130686 178 QIQRELGLTTIFVTHDQEEALTmSDRIFLMNQGKIVQSGDAETLY 222
Cdd:PRK13648 187 KVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIF 230
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-221 4.98e-42

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 147.56  E-value: 4.98e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdivPLSPQKRH-IGmvfq 82
Cdd:COG4152    2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGE---PLDPEDRRrIG---- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 sY-----ALFPNMTV-EQNVAFGlRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:COG4152   75 -YlpeerGLYPKMKVgEQLVYLA-RLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLI 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:COG4152  153 LDEPFSGLDPVNVELLKDVIRELAAK-GTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEI 216
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 5-213 7.39e-42

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 144.32  E-value: 7.39e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSY-AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRhIGMVFQS 83
Cdd:cd03226    1 RIENISFSYkKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKERRKS-IGYVMQD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 --YALFPNmTVEQNVAFGLRmqkvNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:cd03226   80 vdYQLFTD-SVREELLLGLK----ELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPT 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 545130686 162 SALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIV 213
Cdd:cd03226  155 SGLDYKNMERVGELIRELAAQ-GKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 14-219 1.34e-41

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 151.82  E-value: 1.34e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  14 AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMVFQSYALFPNmT 91
Cdd:COG4618  343 SKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREElgRHIGYLPQDVELFDG-T 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  92 VEQNVAfglRMQKVNADDshkrVQEVLQLVELKDLAGRYP-----------HQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:COG4618  422 IAENIA---RFGDADPEK----VVAAAKLAGVHEMILRLPdgydtrigeggARLSGGQRQRIGLARALYGDPRLVVLDEP 494

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 161 LSALDARIRKHLREQIRQIqRELGLTTIFVTHDQeEALTMSDRIFLMNQGKIVQSGDAE 219
Cdd:COG4618  495 NSNLDDEGEAALAAAIRAL-KARGATVVVITHRP-SLLAAVDKLLVLRDGRVQAFGPRD 551
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
1-225 1.43e-41

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 145.37  E-value: 1.43e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYA-GTPVFS--------DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLS 71
Cdd:COG4167    2 SALLEVRNLSKTFKyRTGLFRrqqfeavkPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLEYGD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  72 PQKR--HIGMVFQ--SYALFPNMTVEQNVAFGLRMQ-KVNADDSHKRVQEVLQLVEL-KDLAGRYPHQMSGGQCQRVALA 145
Cdd:COG4167   82 YKYRckHIRMIFQdpNTSLNPRLNIGQILEEPLRLNtDLTAEEREERIFATLRLVGLlPEHANFYPHMLSSGQKQRVALA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 146 RSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:COG4167  162 RALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEVFANP 241
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
1-221 3.05e-41

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 144.52  E-value: 3.05e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK-----R 75
Cdd:PRK11831   5 ANLVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRlytvrK 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  76 HIGMVFQSYALFPNMTVEQNVAFGLRMQ-KVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRL 154
Cdd:PRK11831  85 RMSMLFQSGALFTDMNVFDNVAYPLREHtQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDL 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 155 LLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:PRK11831 165 IMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL 231
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
1-214 5.27e-41

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 144.06  E-value: 5.27e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTP---------VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLS 71
Cdd:PRK10419   1 MTLLNVSGLSHHYAHGGlsgkhqhqtVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  72 PQ-----KRHIGMVFQSY--ALFPNMTVEQNVAFGLR-MQKVNADDSHKRVQEVLQLVELKD-LAGRYPHQMSGGQCQRV 142
Cdd:PRK10419  81 RAqrkafRRDIQMVFQDSisAVNPRKTVREIIREPLRhLLSLDKAERLARASEMLRAVDLDDsVLDKRPPQLSGGQLQRV 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 545130686 143 ALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQ 214
Cdd:PRK10419 161 CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVE 232
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 16-216 2.89e-40

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 140.42  E-value: 2.89e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  16 TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFpNMTVE 93
Cdd:cd03245   17 IPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPAdlRRNIGYVPQDVTLF-YGTLR 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  94 QNVAFGlrmqKVNADDShkRVQEVLQLVELKDLAGRYPH-----------QMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:cd03245   96 DNITLG----APLADDE--RILRAAELAGVTDFVNKHPNgldlqigergrGLSGGQRQAVALARALLNDPPILLLDEPTS 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 545130686 163 ALDARIRKHLREQIRQIQRelGLTTIFVTHDQeEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03245  170 AMDMNSEERLKERLRQLLG--DKTLIIITHRP-SLLDLVDRIIVMDSGRIVADG 220
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
34-226 3.17e-40

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 144.25  E-value: 3.17e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  34 LLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQ---DI---VPLSPQKRHIGMVFQSYALFPNMTVEQNVAFGLRmqkvna 107
Cdd:PRK11144  29 IFGRSGAGKTSLINAISGLTRPQKGRIVLNGRvlfDAekgICLPPEKRRIGYVFQDARLFPHYKVRGNLRYGMA------ 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 108 ddsHKRVQEVLQLVEL---KDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELG 184
Cdd:PRK11144 103 ---KSMVAQFDKIVALlgiEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREIN 179

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 545130686 185 LTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPV 226
Cdd:PRK11144 180 IPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASSA 221
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 15-221 3.38e-40

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 140.83  E-value: 3.38e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  15 GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGMVFQSYALFpNMTV 92
Cdd:cd03253   13 GRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIreVTLDSLRRAIGVVPQDTVLF-NDTI 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  93 EQNVAFGlrmqKVNADDshKRVQEVLQLVELKDLAGRYPHQ-----------MSGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:cd03253   92 GYNIRYG----RPDATD--EEVIEAAKAAQIHDKIMRFPDGydtivgerglkLSGGEKQRVAIARAILKNPPILLLDEAT 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 162 SALDARIRKHLREQIRQIQRelGLTTIFVTHDQEEALTmSDRIFLMNQGKIVQSGDAETL 221
Cdd:cd03253  166 SALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTHEEL 222
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 15-230 4.09e-40

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 141.75  E-value: 4.09e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  15 GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI----VPLSPQKRHIGMVFQSY--ALFP 88
Cdd:PRK13639  14 GTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIkydkKSLLEVRKTVGIVFQNPddQLFA 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  89 NmTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARI 168
Cdd:PRK13639  94 P-TVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMG 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 545130686 169 RKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGdaetlytAPVDVFA 230
Cdd:PRK13639 173 ASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEG-------TPKEVFS 226
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 4-222 6.31e-40

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 140.06  E-value: 6.31e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGT--PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGM 79
Cdd:cd03251    1 VEFKNVTFRYPGDgpPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVrdYTLASLRRQIGL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFpNMTVEQNVAFGLRmqkvnaDDSHKRVQEVLQLVELKDLAGRYPH-----------QMSGGQCQRVALARSL 148
Cdd:cd03251   81 VSQDVFLF-NDTVAENIAYGRP------GATREEVEEAARAANAHEFIMELPEgydtvigergvKLSGGQRQRIAIARAL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 149 VTRPRLLLLDEPLSALDARIRKHLREQIRQIQRelGLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAETLY 222
Cdd:cd03251  154 LKDPPILILDEATSALDTESERLVQAALERLMK--NRTTFVIAH-RLSTIENADRIVVLEDGKIVERGTHEELL 224
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 4-220 1.58e-39

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 145.55  E-value: 1.58e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ---KRHIGMV 80
Cdd:COG3845    6 LELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPRdaiALGIGMV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGL---RMQKVNADDSHKRVQEVLQLVELK-DLAgRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:COG3845   86 HQHFMLVPNLTVAENIVLGLeptKGGRLDRKAARARIRELSERYGLDvDPD-AKVEDLSVGEQQRVEILKALYRGARILI 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGD-AET 220
Cdd:COG3845  165 LDEPTAVLTPQEADELFEILRRLAAE-GKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDtAET 228
cbiO PRK13640
energy-coupling factor transporter ATPase;
2-229 8.07e-39

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 138.78  E-value: 8.07e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   2 SFVSVQHLQKSYAGT--PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDS---GKILLDGqdiVPLSPQ--- 73
Cdd:PRK13640   4 NIVEFKHVSFTYPDSkkPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDnpnSKITVDG---ITLTAKtvw 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  74 --KRHIGMVFQSY-ALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVT 150
Cdd:PRK13640  81 diREKVGIVFQNPdNQFVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAV 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 151 RPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEAlTMSDRIFLMNQGKIVQSGdaetlytAPVDVF 229
Cdd:PRK13640 161 EPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQG-------SPVEIF 231
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 17-222 9.66e-39

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 137.29  E-value: 9.66e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFpNMTVEQ 94
Cdd:cd03249   17 PILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRwlRSQIGLVSQEPVLF-DGTIAE 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  95 NVAFGlrmqKVNADDSHkrVQEVLQLVELKD-----------LAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:cd03249   96 NIRYG----KPDATDEE--VEEAAKKANIHDfimslpdgydtLVGERGSQLSGGQKQRIAIARALLRNPKILLLDEATSA 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 164 LDARIRKHLREQIRQIQRelGLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAETLY 222
Cdd:cd03249  170 LDAESEKLVQEALDRAMK--GRTTIVIAH-RLSTIRNADLIAVLQNGQVVEQGTHDELM 225
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
16-216 1.57e-38

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 137.91  E-value: 1.57e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  16 TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ---KRHIGMVFQSyalfPN--- 89
Cdd:PRK13633  23 KLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENLwdiRNKAGMVFQN----PDnqi 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  90 --MTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDAR 167
Cdd:PRK13633  99 vaTIVEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPS 178

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 545130686 168 IRKHLREQIRQIQRELGLTTIFVTHDQEEALTmSDRIFLMNQGKIVQSG 216
Cdd:PRK13633 179 GRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEG 226
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 5-212 3.65e-38

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 133.50  E-value: 3.65e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGT--PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMV 80
Cdd:cd03246    2 EVENVSFRYPGAepPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNelGDHVGYL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNmTVEQNVafglrmqkvnaddshkrvqevlqlvelkdlagryphqMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:cd03246   82 PQDDELFSG-SIAENI-------------------------------------LSGGQRQRLGLARALYGNPRILVLDEP 123

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 545130686 161 LSALDARIRKHLREQIRQIqRELGLTTIFVTHdQEEALTMSDRIFLMNQGKI 212
Cdd:cd03246  124 NSHLDVEGERALNQAIAAL-KAAGATRIVIAH-RPETLASADRILVLEDGRV 173
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 6-210 8.33e-38

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 134.48  E-value: 8.33e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYA-----GT--PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQ----DIVPLSPQ- 73
Cdd:COG4778    7 VENLSKTFTlhlqgGKrlPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDggwvDLAQASPRe 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  74 -----KRHIGMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKD-LAGRYPHQMSGGQCQRVALARS 147
Cdd:COG4778   87 ilalrRRTIGYVSQFLRVIPRVSALDVVAEPLLERGVDREEARARARELLARLNLPErLWDLPPATFSGGEQQRVNIARG 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545130686 148 LVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQG 210
Cdd:COG4778  167 FIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRVVDVTPF 228
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
 20-225 1.00e-37

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 134.42  E-value: 1.00e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   20 SDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGL----TSVDSGKILLDGQDIVPLSPQKRHIGMVFQS--YALFPNMTVE 93
Cdd:TIGR02770   3 QDLNLSLKRGEVLALVGESGSGKSLTCLAILGLlppgLTQTSGEILLDGRPLLPLSIRGRHIATIMQNprTAFNPLFTMG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   94 QNVAFGLRMQKVNADDSHKRVQEVLQLVELKD---LAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRK 170
Cdd:TIGR02770  83 NHAIETLRSLGKLSKQARALILEALEAVGLPDpeeVLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDLDVVNQA 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 545130686  171 HLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:TIGR02770 163 RVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNP 217
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 25-225 1.04e-37

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 137.02  E-value: 1.04e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  25 EVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRH-----IGMVFQS-YA-LFPNMTVEQNVA 97
Cdd:PRK11308  37 TLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADPEAQKllrqkIQIVFQNpYGsLNPRKKVGQILE 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  98 FGLrmqKVNADDSHK----RVQEVLQLVELK-DLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHL 172
Cdd:PRK11308 117 EPL---LINTSLSAAerreKALAMMAKVGLRpEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQV 193

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 545130686 173 REQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK11308 194 LNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNP 246
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 1-225 3.01e-37

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 133.88  E-value: 3.01e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVD-----SGKILLDGQDI--VPLSPQ 73
Cdd:PRK14247   1 MNKIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIELYpearvSGEVYLDGQDIfkMDVIEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  74 KRHIGMVFQSYALFPNMTVEQNVAFGLRMQKV--NADDSHKRVQEVLQLVEL----KDLAGRYPHQMSGGQCQRVALARS 147
Cdd:PRK14247  81 RRRVQMVFQIPNPIPNLSIFENVALGLKLNRLvkSKKELQERVRWALEKAQLwdevKDRLDAPAGKLSGGQQQRLCIARA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 148 LVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRElgLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK14247 161 LAFQPEVLLADEPTANLDPENTAKIESLFLELKKD--MTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNP 236
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 7-196 3.99e-36

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 129.83  E-value: 3.99e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   7 QHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSY 84
Cdd:PRK10247  11 QNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEiyRQQVSYCAQTP 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  85 ALFPNmTVEQNVAFGLRMQKVNADDshKRVQEVLQLVELKD-LAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:PRK10247  91 TLFGD-TVYDNLIFPWQIRNQQPDP--AIFLDDLERFALPDtILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSA 167

                        170       180       190
                 ....*....|....*....|....*....|...
gi 545130686 164 LDARIRKHLREQIRQIQRELGLTTIFVTHDQEE 196
Cdd:PRK10247 168 LDESNKHNVNEIIHRYVREQNIAVLWVTHDKDE 200
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 1-225 4.63e-36

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 131.46  E-value: 4.63e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGT-PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP--LSPQKRHI 77
Cdd:PRK13652   1 MHLIETRDLCYSYSGSkEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKenIREVRKFV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVFQSY--ALFpNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLL 155
Cdd:PRK13652  81 GLVFQNPddQIF-SPTVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 156 LLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK13652 160 VLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
cbiO PRK13642
energy-coupling factor transporter ATPase;
22-233 4.77e-36

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 131.37  E-value: 4.77e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  22 INCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP--LSPQKRHIGMVFQSY-ALFPNMTVEQNVAF 98
Cdd:PRK13642  26 VSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAenVWNLRRKIGMVFQNPdNQFVGATVEDDVAF 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  99 GLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQ 178
Cdd:PRK13642 106 GMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHE 185

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 179 IQRELGLTTIFVTHDQEEALTmSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGF 233
Cdd:PRK13642 186 IKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELFATSEDMVEIGL 239
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 14-224 5.61e-36

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 137.30  E-value: 5.61e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   14 AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFpNMT 91
Cdd:TIGR03375 476 QETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPAdlRRNIGYVPQDPRLF-YGT 554

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   92 VEQNVAFGLRmqkvNADDShkRVQEVLQLVELKDLAGRYPH-----------QMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:TIGR03375 555 LRDNIALGAP----YADDE--EILRAAELAGVTEFVRRHPDgldmqigergrSLSGGQRQAVALARALLRDPPILLLDEP 628

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686  161 LSALDARIRKHLREQIRQIQRelGLTTIFVTHDQeEALTMSDRIFLMNQGKIVQSGDAETLYTA 224
Cdd:TIGR03375 629 TSAMDNRSEERFKDRLKRWLA--GKTLVLVTHRT-SLLDLVDRIIVMDNGRIVADGPKDQVLEA 689
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 4-230 5.81e-36

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 131.12  E-value: 5.81e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYA-GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI----VPLSPQKRHIG 78
Cdd:PRK13636   6 LKVEELNYNYSdGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIdysrKGLMKLRESVG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  79 MVFQS--YALFpNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:PRK13636  86 MVFQDpdNQLF-SASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLV 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDaetlytaPVDVFA 230
Cdd:PRK13636 165 LDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGN-------PKEVFA 231
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 5-231 8.81e-36

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 130.11  E-value: 8.81e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHiGMV-- 80
Cdd:PRK11300   7 SVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQiaRM-GVVrt 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQN--VAfglRMQKVNA----------------DDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRV 142
Cdd:PRK11300  86 FQHVRLFREMTVIENllVA---QHQQLKTglfsgllktpafrraeSEALDRAATWLERVGLLEHANRQAGNLAYGQQRRL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 143 ALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLY 222
Cdd:PRK11300 163 EIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIR 242


                 ....*....
gi 545130686 223 TAPvDVFAA 231
Cdd:PRK11300 243 NNP-DVIKA 250
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 4-225 2.46e-35

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 128.81  E-value: 2.46e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVD-----SGKILLDGQDIvpLSPQ----- 73
Cdd:PRK14267   5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeearvEGEVRLFGRNI--YSPDvdpie 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  74 -KRHIGMVFQSYALFPNMTVEQNVAFGLRMQKV--NADDSHKRVQEVLQLV----ELKDLAGRYPHQMSGGQCQRVALAR 146
Cdd:PRK14267  83 vRREVGMVFQYPNPFPHLTIYDNVAIGVKLNGLvkSKKELDERVEWALKKAalwdEVKDRLNDYPSNLSGGQRQRLVIAR 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 147 SLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRElgLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK14267 163 ALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKE--YTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENP 239
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
6-256 2.79e-35

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 128.59  E-value: 2.79e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMVFQS 83
Cdd:PRK11231   5 TENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQlaRRLALLPQH 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YALFPNMTVEQNVAFGlRMQKVN-----ADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLD 158
Cdd:PRK11231  85 HLTPEGITVRELVAYG-RSPWLSlwgrlSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLD 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 159 EPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGdaetlytAPVDVFAAGFIGNYN 238
Cdd:PRK11231 164 EPTTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGHVMAQG-------TPEEVMTPGLLRTVF 235

                        250
                 ....*....|....*...
gi 545130686 239 LLDAdkatQLLQRPISSR 256
Cdd:PRK11231 236 DVEA----EIHPEPVSGT 249
cbiO PRK13644
energy-coupling factor transporter ATPase;
15-225 3.27e-35

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 128.95  E-value: 3.27e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  15 GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKIL---LDGQDIVPLSPQKRHIGMVFQS-YALFPNM 90
Cdd:PRK13644  14 GTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLvsgIDTGDFSKLQGIRKLVGIVFQNpETQFVGR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  91 TVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRK 170
Cdd:PRK13644  94 TVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGI 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 171 HLREQIRQIQRElGLTTIFVTHDQEEaLTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK13644 174 AVLERIKKLHEK-GKTIVYITHNLEE-LHDADRIIVMDRGKIVLEGEPENVLSDV 226
type_I_sec_HlyB TIGR01846
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ...
 17-221 6.65e-35

type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273831 [Multi-domain]  Cd Length: 694  Bit Score: 134.48  E-value: 6.65e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFpNMTVEQ 94
Cdd:TIGR01846 471 EVLSNLNLDIKPGEFIGIVGPSGSGKSTLTKLLQRLYTPQHGQVLVDGVDLAIADPAwlRRQMGVVLQENVLF-SRSIRD 549

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   95 NVAFGlrmqKVNADDSHkrVQEVLQLVELKDLAGRYPH-----------QMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:TIGR01846 550 NIALC----NPGAPFEH--VIHAAKLAGAHDFISELPQgyntevgekgaNLSGGQRQRIAIARALVGNPRILIFDEATSA 623

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686  164 LDARIRKHLREQIRQIQRelGLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:TIGR01846 624 LDYESEALIMRNMREICR--GRTVIIIAH-RLSTVRACDRIIVLEKGQIAESGRHEEL 678
cbiO PRK13649
energy-coupling factor transporter ATPase;
8-229 1.31e-34

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 127.55  E-value: 1.31e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   8 HLQK-SY---AGTP----VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK----- 74
Cdd:PRK13649   4 NLQNvSYtyqAGTPfegrALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKdikqi 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  75 -RHIGMVFQsyalFPNM-----TVEQNVAFGLRMQKVNADDSHKRVQEVLQLVEL-KDLAGRYPHQMSGGQCQRVALARS 147
Cdd:PRK13649  84 rKKVGLVFQ----FPESqlfeeTVLKDVAFGPQNFGVSQEEAEALAREKLALVGIsESLFEKNPFELSGGQMRRVAIAGI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 148 LVTRPRLLLLDEPLSALDARIRKHLREQIRQIQrELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGdaetlytAPVD 227
Cdd:PRK13649 160 LAMEPKILVLDEPTAGLDPKGRKELMTLFKKLH-QSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSG-------KPKD 231


                 ..
gi 545130686 228 VF 229
Cdd:PRK13649 232 IF 233
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
4-219 1.59e-34

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 125.76  E-value: 1.59e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSY-AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ-----KRHI 77
Cdd:PRK10908   2 IRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNRevpflRRQI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:PRK10908  82 GMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLA 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 545130686 158 DEPLSALDARIRKHLREQIRQIQReLGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAE 219
Cdd:PRK10908 162 DEPTGNLDDALSEGILRLFEEFNR-VGVTVLMATHDIGLISRRSYRMLTLSDGHLHGGVGGE 222
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
4-225 2.62e-34

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 126.24  E-value: 2.62e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIV--------------- 68
Cdd:PRK10619   6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrdkdgqlkvadkn 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  69 PLSPQKRHIGMVFQSYALFPNMTVEQNVAFG-LRMQKVNADDSHKRVQEVLQLVELKDLA-GRYPHQMSGGQCQRVALAR 146
Cdd:PRK10619  86 QLRLLRTRLTMVFQHFNLWSHMTVLENVMEApIQVLGLSKQEARERAVKYLAKVGIDERAqGKYPVHLSGGQQQRVSIAR 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 147 SLVTRPRLLLLDEPLSALDARIrkhLREQIRQIQR--ELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTA 224
Cdd:PRK10619 166 ALAMEPEVLLFDEPTSALDPEL---VGEVLRIMQQlaEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGN 242


                 .
gi 545130686 225 P 225
Cdd:PRK10619 243 P 243
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 12-216 4.49e-34

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 123.43  E-value: 4.49e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  12 SYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSV--DSGKILLDGQDIVPLSPqKRHIGMVFQSYALFPN 89
Cdd:cd03213   18 SKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGlgVSGEVLINGRPLDKRSF-RKIIGYVPQDDILHPT 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  90 MTVEQNVAFGLRMQKVnaddshkrvqevlqlvelkdlagryphqmSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIR 169
Cdd:cd03213   97 LTVRETLMFAAKLRGL-----------------------------SGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSA 147

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 545130686 170 KHLREQIRQIqRELGLTTIFVTHD-QEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03213  148 LQVMSLLRRL-ADTGRTIICSIHQpSSEIFELFDKLLLLSQGRVIYFG 194
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
12-206 4.93e-34

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 123.50  E-value: 4.93e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  12 SYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGmvfqsyALFPnMT 91
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVAYVPQRSEVP------DSLP-LT 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  92 VEQNVAFGL-----RMQKVNADDsHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDA 166
Cdd:NF040873  74 VRDLVAMGRwarrgLWRRLTRDD-RAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDA 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 545130686 167 RIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFL 206
Cdd:NF040873 153 ESRERIIALLAEEHAR-GATVVVVTHDLELVRRADPCVLL 191
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 15-221 4.97e-34

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 126.00  E-value: 4.97e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  15 GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSY--ALFpNM 90
Cdd:PRK13647  17 GTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKwvRSKVGLVFQDPddQVF-SS 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  91 TVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRK 170
Cdd:PRK13647  96 TVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQE 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 545130686 171 HLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:PRK13647 176 TLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLL 225
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 18-225 5.56e-34

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 130.60  E-value: 5.56e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  18 VFSDINCEVAKGEFVTLLGPSGCGKST----LLRCIAGltsvdSGKILLDGQDIVPLS-----PQKRHIGMVFQ--SYAL 86
Cdd:PRK15134 301 VVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLINS-----QGEIWFDGQPLHNLNrrqllPVRHRIQVVFQdpNSSL 375

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  87 FPNMTVEQNVAFGLRMQK--VNADDSHKRVQEVLQLVELK-DLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:PRK15134 376 NPRLNVLQIIEEGLRVHQptLSAAQREQQVIAVMEEVGLDpETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSS 455

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 545130686 164 LDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK15134 456 LDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAP 517
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 4-211 6.71e-34

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 123.35  E-value: 6.71e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGqdivplspqkrHIGMVFQS 83
Cdd:cd03250    6 ASFTWDSGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG-----------SIAYVSQE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 yALFPNMTVEQNVAFGLRMqkvnaddSHKRVQEVLQLVEL-KDLAgRYPHQ-----------MSGGQCQRVALARSLVTR 151
Cdd:cd03250   75 -PWIQNGTIRENILFGKPF-------DEERYEKVIKACALePDLE-ILPDGdlteigekginLSGGQKQRISLARAVYSD 145

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 545130686 152 PRLLLLDEPLSALDARIRKHLREQIrqIQREL--GLTTIFVTHdQEEALTMSDRIFLMNQGK 211
Cdd:cd03250  146 ADIYLLDDPLSAVDAHVGRHIFENC--ILGLLlnNKTRILVTH-QLQLLPHADQIVVLDNGR 204
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
16-214 1.03e-33

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 123.77  E-value: 1.03e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  16 TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP------QKRHIGMVFQSYALFPN 89
Cdd:PRK11629  22 TDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSaakaelRNQKLGFIYQFHHLLPD 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  90 MTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIR 169
Cdd:PRK11629 102 FTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNA 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 545130686 170 KHLREQIRQIQRELGLTTIFVTHDQEEALTMSdRIFLMNQGKIVQ 214
Cdd:PRK11629 182 DSIFQLLGELNRLQGTAFLVVTHDLQLAKRMS-RQLEMRDGRLTA 225
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 4-216 1.13e-33

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 124.17  E-value: 1.13e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLS------PQKRHI 77
Cdd:TIGR02323   4 LQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSGAELElyqlseAERRRL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   78 -----GMVFQSYALFPNMTVEQNVAFGLRMQKVNA---DDSHKRVQEVLQLVELKdlAGRY---PHQMSGGQCQRVALAR 146
Cdd:TIGR02323  84 mrtewGFVHQNPRDGLRMRVSAGANIGERLMAIGArhyGNIRATAQDWLEEVEID--PTRIddlPRAFSGGMQQRLQIAR 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  147 SLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:TIGR02323 162 NLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESG 231
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 22-234 1.51e-33

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 123.80  E-value: 1.51e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  22 INCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSvDSGKILLDGQDIVPLSPQK--RHIGMVFQSYALFPNMTVEQNVAFG 99
Cdd:COG4138   15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGLLP-GQGEILLNGRPLSDWSAAElaRHRAYLSQQQSPPFAMPVFQYLALH 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 100 LRmQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVT-------RPRLLLLDEPLSALDARIRKHL 172
Cdd:COG4138   94 QP-AGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvwptinpEGQLLLLDEPMNSLDVAQQAAL 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 173 REQIRQIqRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPV--DVFAAGFI 234
Cdd:COG4138  173 DRLLREL-CQQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMTPENlsEVFGVKFR 235
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 12-221 1.90e-33

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 123.10  E-value: 1.90e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  12 SYA-GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGMVFQSYALFP 88
Cdd:cd03254   11 SYDeKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIrdISRKSLRSMIGVVLQDTFLFS 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  89 NmTVEQNVAFGlrmqKVNADDshKRVQEVLQLVELKDLAGRYP-----------HQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:cd03254   91 G-TIMENIRLG----RPNATD--EEVIEAAKEAGAHDFIMKLPngydtvlgengGNLSQGERQLLAIARAMLRDPKILIL 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 158 DEPLSALDARIRKHLREQIRQIQRelGLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:cd03254  164 DEATSNIDTETEKLIQEALEKLMK--GRTSIIIAH-RLSTIKNADKILVLDDGKIIEEGTHDEL 224
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 5-216 2.68e-33

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 123.50  E-value: 2.68e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLS------PQKRHIG 78
Cdd:PRK11701   8 SVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDlyalseAERRRLL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  79 MVFQSYalfpnmtVEQNVAFGLRMQkVNADDShkrVQEVLQLV------ELKDLAGRY--------------PHQMSGGQ 138
Cdd:PRK11701  88 RTEWGF-------VHQHPRDGLRMQ-VSAGGN---IGERLMAVgarhygDIRATAGDWlerveidaariddlPTTFSGGM 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 139 CQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:PRK11701 157 QQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESG 234
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 12-207 3.49e-33

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 128.17  E-value: 3.49e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   12 SYAGT-PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFP 88
Cdd:TIGR02857 330 AYPGRrPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADswRDQIAWVPQHPFLFA 409

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   89 NmTVEQNVAFGLRmqkvnaDDSHKRVQEVLQLVELKDL-----------AGRYPHQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:TIGR02857 410 G-TIAENIRLARP------DASDAEIREALERAGLDEFvaalpqgldtpIGEGGAGLSGGQAQRLALARAFLRDAPLLLL 482

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 545130686  158 DEPLSALDARIRKHLREQIRQIQRelGLTTIFVTHDQEEALTMsDRIFLM 207
Cdd:TIGR02857 483 DEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLALAALA-DRIVVL 529
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 22-219 5.11e-33

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 127.61  E-value: 5.11e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   22 INCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKI-LLDGQDIVPLSPQ--------KRHIGMVFQSYALFPNMTV 92
Cdd:TIGR03269 303 VSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVnVRVGDEWVDMTKPgpdgrgraKRYIGILHQEYDLYPHRTV 382

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   93 EQNV--AFGLRMQkvnadDSHKRVQEVLQLV-------ELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:TIGR03269 383 LDNLteAIGLELP-----DELARMKAVITLKmvgfdeeKAEEILDKYPDELSEGERHRVALAQVLIKEPRIVILDEPTGT 457

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686  164 LDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAE 219
Cdd:TIGR03269 458 MDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPE 513
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 4-221 6.60e-33

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 128.02  E-value: 6.60e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSY--AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGM 79
Cdd:PRK11160 339 LTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAalRQAISV 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFpNMTVEQNvafgLRMQKVNADDShkRVQEVLQLVELKDLA-------------GRyphQMSGGQCQRVALAR 146
Cdd:PRK11160 419 VSQRVHLF-SATLRDN----LLLAAPNASDE--ALIEVLQQVGLEKLLeddkglnawlgegGR---QLSGGEQRRLGIAR 488

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 147 SLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRelGLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:PRK11160 489 ALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQ--NKTVLMITH-RLTGLEQFDRICVMDNGQIIEQGTHQEL 560
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 4-226 6.86e-33

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 122.19  E-value: 6.86e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVD-----SGKILLDGQDIvpLSPQ----- 73
Cdd:PRK14239   6 LQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLNpevtiTGSIVYNGHNI--YSPRtdtvd 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  74 -KRHIGMVFQSYALFPnMTVEQNVAFGLRMQKVNadDSH---KRVQEVLQLV----ELKDLAGRYPHQMSGGQCQRVALA 145
Cdd:PRK14239  84 lRKEIGMVFQQPNPFP-MSIYENVVYGLRLKGIK--DKQvldEAVEKSLKGAsiwdEVKDRLHDSALGLSGGQQQRVCIA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 146 RSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRElgLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK14239 161 RVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDD--YTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFMNP 238


                 .
gi 545130686 226 V 226
Cdd:PRK14239 239 K 239
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 4-221 1.10e-32

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 127.14  E-value: 1.10e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    4 VSVQHLQKSYAGT--PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGM 79
Cdd:TIGR02203 331 VEFRNVTFRYPGRdrPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLAslRRQVAL 410

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   80 VFQSYALFpNMTVEQNVAFGLRMQKVNAddshkRVQEVLQLVELKDLAGRYP---HQ--------MSGGQCQRVALARSL 148
Cdd:TIGR02203 411 VSQDVVLF-NDTIANNIAYGRTEQADRA-----EIERALAAAYAQDFVDKLPlglDTpigengvlLSGGQRQRLAIARAL 484

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686  149 VTRPRLLLLDEPLSALDArirkhlrEQIRQIQREL-----GLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:TIGR02203 485 LKDAPILILDEATSALDN-------ESERLVQAALerlmqGRTTLVIAH-RLSTIEKADRIVVMDDGRIVERGTHNEL 554
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 4-227 1.59e-32

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 121.68  E-value: 1.59e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDS-----GKILLDGQDI----VPLSPQK 74
Cdd:PRK14258   8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESevrveGRVEFFNQNIyerrVNLNRLR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  75 RHIGMVFQSYALFPnMTVEQNVAFGLRM----QKVNADDShkrVQEVLQLVELKDLAGRYPHQ----MSGGQCQRVALAR 146
Cdd:PRK14258  88 RQVSMVHPKPNLFP-MSVYDNVAYGVKIvgwrPKLEIDDI---VESALKDADLWDEIKHKIHKsaldLSGGQQQRLCIAR 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 147 SLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSD--RIFLMNQ---GKIVQSGDAETL 221
Cdd:PRK14258 164 ALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDftAFFKGNEnriGQLVEFGLTKKI 243


                 ....*.
gi 545130686 222 YTAPVD 227
Cdd:PRK14258 244 FNSPHD 249
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 4-212 1.67e-32

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 119.07  E-value: 1.67e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQksyaGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRH-IGMVF- 81
Cdd:cd03215    5 LEVRGLS----VKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAIrAGIAYv 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 ----QSYALFPNMTVEQNVAFglrmqkvnaddshkrvqevlqlvelkdlagryPHQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:cd03215   81 pedrKREGLVLDLSVAENIAL--------------------------------SSLLSGGNQQKVVLARWLARDPRVLIL 128

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 158 DEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKI 212
Cdd:cd03215  129 DEPTRGVDVGAKAEIYRLIRELADA-GKAVLLISSELDELLGLCDRILVMYEGRI 182
cbiO PRK13646
energy-coupling factor transporter ATPase;
4-222 4.42e-32

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 121.04  E-value: 4.42e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYA---GTP----VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP------L 70
Cdd:PRK13646   1 MTIRFDNVSYTyqkGTPyehqAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHktkdkyI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  71 SPQKRHIGMVFQ--SYALFPNmTVEQNVAFGLRMQKVNADDSHKRVQEVL-QLVELKDLAGRYPHQMSGGQCQRVALARS 147
Cdd:PRK13646  81 RPVRKRIGMVFQfpESQLFED-TVEREIIFGPKNFKMNLDEVKNYAHRLLmDLGFSRDVMSQSPFQMSGGQMRKIAIVSI 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 148 LVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLY 222
Cdd:PRK13646 160 LAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELF 234
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 18-216 4.89e-32

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 119.17  E-value: 4.89e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  18 VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSpqkrhIGMVFQsyalfPNMTVEQNVA 97
Cdd:cd03220   37 ALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVSSLLG-----LGGGFN-----PELTGRENIY 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  98 FGLRMQKVNADDSHKRVQEVLQLVELKDLA----GRYphqmSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLR 173
Cdd:cd03220  107 LNGRLLGLSRKEIDEKIDEIIEFSELGDFIdlpvKTY----SSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQ 182

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 545130686 174 EQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03220  183 RRLRELLKQ-GKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 18-221 4.97e-32

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 119.51  E-value: 4.97e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  18 VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFpNMTVEQN 95
Cdd:cd03252   17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAwlRRQVGVVLQENVLF-NRSIRDN 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  96 VAFGlrmqkvNADDSHKRVQEVLQLVELKDLAGRYPH-----------QMSGGQCQRVALARSLVTRPRLLLLDEPLSAL 164
Cdd:cd03252   96 IALA------DPGMSMERVIEAAKLAGAHDFISELPEgydtivgeqgaGLSGGQRQRIAIARALIHNPRILIFDEATSAL 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 165 DARIRKHLREQIRQIQRelGLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:cd03252  170 DYESEHAIMRNMHDICA--GRTVIIIAH-RLSTVKNADRIIVMEKGRIVEQGSHDEL 223
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 29-225 9.32e-32

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 124.97  E-value: 9.32e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  29 GEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK-----RHIGMVFQS-YA-LFPNMTVEQNVAFGLR 101
Cdd:PRK10261 350 GETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKlqalrRDIQFIFQDpYAsLDPRQTVGDSIMEPLR 429

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 102 MQKV-NADDSHKRVQEVLQLVELK-DLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQI 179
Cdd:PRK10261 430 VHGLlPGKAAAARVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDL 509

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 545130686 180 QRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK10261 510 QRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENP 555
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 18-216 1.04e-31

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 118.53  E-value: 1.04e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  18 VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGL---TSVDSGKILLDGQdivPLSPQ--KRHIGMVFQSYALFPNMTV 92
Cdd:cd03234   22 ILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRvegGGTTSGQILFNGQ---PRKPDqfQKCVAYVRQDDILLPGLTV 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  93 EQNVAFG--LRMQKVNADDSHKRVQEVLQL--VELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARI 168
Cdd:cd03234   99 RETLTYTaiLRLPRKSSDAIRKKRVEDVLLrdLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFT 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 545130686 169 RKHLREQIRQIQRE--LGLTTIfvtHD-QEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03234  179 ALNLVSTLSQLARRnrIVILTI---HQpRSDLFRLFDRILLLSSGEIVYSG 226
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 2-208 1.49e-31

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 117.96  E-value: 1.49e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   2 SFVSVQHLQKSYAG----TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR-- 75
Cdd:PRK10584   5 NIVEVHHLKKSVGQgeheLSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARak 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  76 ----HIGMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTR 151
Cdd:PRK10584  85 lrakHVGFVFQSFMLIPTLNALENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGR 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 152 PRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMN 208
Cdd:PRK10584 165 PDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAARCDRRLRLVN 221
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 17-221 1.57e-31

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 124.16  E-value: 1.57e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGMVFQSYALFpNMTVEQ 94
Cdd:COG5265  372 PILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIrdVTQASLRAAIGIVPQDTVLF-NDTIAY 450

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  95 NVAFGlrmqkvNADDSHKRVQEVLQLVELKDLAGRYPHQM-----------SGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:COG5265  451 NIAYG------RPDASEEEVEAAARAAQIHDFIESLPDGYdtrvgerglklSGGEKQRVAIARTLLKNPPILIFDEATSA 524

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 164 LDARIRKHLREQIRQIQRelGLTTIFVTH------DqeealtmSDRIFLMNQGKIVQSGDAETL 221
Cdd:COG5265  525 LDSRTERAIQAALREVAR--GRTTLVIAHrlstivD-------ADEILVLEAGRIVERGTHAEL 579
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 16-219 2.72e-31

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 123.23  E-value: 2.72e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   16 TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMVFQSYALFPNmTVE 93
Cdd:TIGR01842 331 KPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETfgKHIGYLPQDVELFPG-TVA 409

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   94 QNVAfglRMQKvNADDshKRVQEVLQLVELKDLAGRYPH-----------QMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:TIGR01842 410 ENIA---RFGE-NADP--EKIIEAAKLAGVHELILRLPDgydtvigpggaTLSGGQRQRIALARALYGDPKLVVLDEPNS 483

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686  163 ALDARIRKHLREQIRQIQRElGLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAE 219
Cdd:TIGR01842 484 NLDEEGEQALANAIKALKAR-GITVVVITH-RPSLLGCVDKILVLQDGRIARFGERD 538
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 4-231 3.59e-31

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 122.47  E-value: 3.59e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRH---IGMV 80
Cdd:PRK15439  12 LCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAKAHqlgIYLV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQNVAFGLrmqkVNADDSHKRVQEVLQL--VELK--------DLAGRyphqmsggqcQRVALARSLVT 150
Cdd:PRK15439  92 PQEPLLFPNLSVKENILFGL----PKRQASMQKMKQLLAAlgCQLDldssagslEVADR----------QIVEILRGLMR 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 151 RPRLLLLDEPLSALDARIRKHLREQIRQIQrELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTApvDVFA 230
Cdd:PRK15439 158 DSRILILDEPTASLTPAETERLFSRIRELL-AQGVGIVFISHKLPEIRQLADRISVMRDGTIALSGKTADLSTD--DIIQ 234


                 .
gi 545130686 231 A 231
Cdd:PRK15439 235 A 235
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 1-221 6.04e-31

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 116.92  E-value: 6.04e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQ-KRHI 77
Cdd:PRK10895   1 MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDIslLPLHARaRRGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVFQSYALFPNMTVEQNVAFGLRMQK-VNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:PRK10895  81 GYLPQEASIFRRLSVYDNLMAVLQIRDdLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFIL 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 545130686 157 LDEPLSALD-------ARIRKHLREQirqiqrelGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:PRK10895 161 LDEPFAGVDpisvidiKRIIEHLRDS--------GLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEI 224
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 12-225 8.15e-31

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 122.26  E-value: 8.15e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  12 SYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVdSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFPN 89
Cdd:PRK11174 359 SPDGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPY-QGSLKINGIELRELDPEswRKHLSWVGQNPQLPHG 437

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  90 mTVEQNVAFGlrmqKVNADDShkRVQEVLQLVELKDLAGRYPH-----------QMSGGQCQRVALARSLVTRPRLLLLD 158
Cdd:PRK11174 438 -TLRDNVLLG----NPDASDE--QLQQALENAWVSEFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQLLLLD 510

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 159 EPLSALDARIRKHLREQIRQIQRelGLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK11174 511 EPTASLDAHSEQLVMQALNAASR--RQTTLMVTH-QLEDLAQWDQIWVMQDGQIVQQGDYAELSQAG 574
cbiO PRK13641
energy-coupling factor transporter ATPase;
15-230 1.00e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 117.24  E-value: 1.00e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  15 GTPV----FSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP------LSPQKRHIGMVFQ-- 82
Cdd:PRK13641  15 GTPMekkgLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPetgnknLKKLRKKVSLVFQfp 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SYALFPNmTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELK-DLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:PRK13641  95 EAQLFEN-TVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLSeDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPA 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 162 SALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQsgdaetlYTAPVDVFA 230
Cdd:PRK13641 174 AGLDPEGRKEMMQLFKDYQKA-GHTVILVTHNMDDVAEYADDVLVLEHGKLIK-------HASPKEIFS 234
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
11-221 1.22e-30

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 118.39  E-value: 1.22e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  11 KSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGqdiVPLSPQKR----HIGMVFQSYAL 86
Cdd:PRK13536  49 KSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLG---VPVPARARlaraRIGVVPQFDNL 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  87 FPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDA 166
Cdd:PRK13536 126 DLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDP 205

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 167 RIRKHLREQIRQIQrELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:PRK13536 206 HARHLIWERLRSLL-ARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHAL 259
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 1-225 1.74e-30

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 119.18  E-value: 1.74e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIG 78
Cdd:PRK09536   1 MPMIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAasRRVA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  79 MVFQSYALFPNMTVEQNVAFGL---RMQKVNADDSHKR-VQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRL 154
Cdd:PRK09536  81 SVPQDTSLSFEFDVRQVVEMGRtphRSRFDTWTETDRAaVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPV 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 155 LLLDEPLSALDarirkhLREQIRQIQ--REL---GLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK09536 161 LLLDEPTASLD------INHQVRTLElvRRLvddGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTAD 230
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 25-233 1.78e-30

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 115.80  E-value: 1.78e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  25 EVAKGEFVTLLGPSGCGKSTLLRCIAGLTSvDSGKILLDGQDI--VPLSPQKRHIGMVFQSYALFPNMTVEQNVAFGLRm 102
Cdd:PRK03695  18 EVRAGEILHLVGPNGAGKSTLLARMAGLLP-GSGSIQFAGQPLeaWSAAELARHRAYLSQQQTPPFAMPVFQYLTLHQP- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 103 QKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALA-------RSLVTRPRLLLLDEPLSALDARIRKHLREQ 175
Cdd:PRK03695  96 DKTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAavvlqvwPDINPAGQLLLLDEPMNSLDVAQQAALDRL 175

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 176 IRQIQReLGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPV--DVFAAGF 233
Cdd:PRK03695 176 LSELCQ-QGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPENlaQVFGVNF 234
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 8-235 1.86e-30

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 116.35  E-value: 1.86e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   8 HLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSV-----DSGKILLDGQDIV---PLSPQKRHIGM 79
Cdd:PRK14271  26 NLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKvsgyrYSGDVLLGGRSIFnyrDVLEFRRRVGM 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPnMTVEQNVAFGLRMQKVNADD-----SHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRL 154
Cdd:PRK14271 106 LFQRPNPFP-MSIMDNVLAGVRAHKLVPRKefrgvAQARLTEVGLWDAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEV 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 155 LLLDEPLSALDARIRKHLREQIRQIQRElgLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVFAAGFI 234
Cdd:PRK14271 185 LLLDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAETARYV 262


                 .
gi 545130686 235 G 235
Cdd:PRK14271 263 A 263
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 18-225 1.91e-30

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 115.91  E-value: 1.91e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  18 VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSV-DS-----GKILLDGQDIVPLSPQK--RHIGMVFQSYALFPN 89
Cdd:PRK14246  25 ILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIyDSkikvdGKVLYFGKDIFQIDAIKlrKEVGMVFQQPNPFPH 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  90 MTVEQNVAFGLRMQKVNADDSHKR-VQEVLQLV----ELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSAL 164
Cdd:PRK14246 105 LSIYDNIAYPLKSHGIKEKREIKKiVEECLRKVglwkEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTSMI 184

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686 165 DARIRKHLREQIRQIQRElgLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK14246 185 DIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSP 243
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 5-219 2.02e-30

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 115.55  E-value: 2.02e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTS--VDSGKILLDGQDIVPLSPQKRH---IGM 79
Cdd:COG0396    2 EIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKyeVTSGSILLDGEDILELSPDERAragIFL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNMTVEQ--NVAFG-LRMQKVNADDSHKRVQEVLQLVEL-KDLAGRYPHQ-MSGGQCQRVALARSLVTRPRL 154
Cdd:COG0396   82 AFQYPVEIPGVSVSNflRTALNaRRGEELSAREFLKLLKEKMKELGLdEDFLDRYVNEgFSGGEKKRNEILQMLLLEPKL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 155 LLLDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHdQEEALTM--SDRIFLMNQGKIVQSGDAE 219
Cdd:COG0396  162 AILDETDSGLDIDALRIVAEGVNKLRSP-DRGILIITH-YQRILDYikPDFVHVLVDGRIVKSGGKE 226
cbiO PRK13645
energy-coupling factor transporter ATPase;
4-230 2.80e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 116.26  E-value: 2.80e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLdGQDIVPLSPQK--------R 75
Cdd:PRK13645  12 VSYTYAKKTPFEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIV-GDYAIPANLKKikevkrlrK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  76 HIGMVFQ--SYALFPNmTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVEL-KDLAGRYPHQMSGGQCQRVALARSLVTRP 152
Cdd:PRK13645  91 EIGLVFQfpEYQLFQE-TIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDG 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 153 RLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGdaetlytAPVDVFA 230
Cdd:PRK13645 170 NTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIG-------SPFEIFS 240
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 18-220 3.55e-30

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 114.79  E-value: 3.55e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  18 VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSpqkrhIGMVFQsyalfPNMTVEQNVA 97
Cdd:COG1134   41 ALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRVSALLE-----LGAGFH-----PELTGRENIY 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  98 FGLRMQKVNADDSHKRVQEVLQLVELKDLA----GRYphqmSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLR 173
Cdd:COG1134  111 LNGRLLGLSRKEIDEKFDEIVEFAELGDFIdqpvKTY----SSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCL 186

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 545130686 174 EQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAET 220
Cdd:COG1134  187 ARIRELRES-GRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEE 232
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 17-225 3.77e-30

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 120.60  E-value: 3.77e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFpNMTVEQ 94
Cdd:TIGR00958 495 PVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHylHRQVALVGQEPVLF-SGSVRE 573

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   95 NVAFGLRmqkvnaDDSHKRVQEVLQLVELKDLAGRYPH-----------QMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:TIGR00958 574 NIAYGLT------DTPDEEIMAAAKAANAHDFIMEFPNgydtevgekgsQLSGGQKQRIAIARALVRKPRVLILDEATSA 647

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545130686  164 LDARIrkhlrEQIRQIQREL-GLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:TIGR00958 648 LDAEC-----EQLLQESRSRaSRTVLLIAH-RLSTVERADQILVLKKGSVVEMGTHKQLMEDQ 704
cbiO PRK13643
energy-coupling factor transporter ATPase;
13-229 8.09e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 115.22  E-value: 8.09e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  13 YAGTPVFsDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDgqDIVPLS--------PQKRHIGMVFQsy 84
Cdd:PRK13643  17 FASRALF-DIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVG--DIVVSStskqkeikPVRKKVGVVFQ-- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  85 alFPNM-----TVEQNVAFGLRMQKVNADDSHKRVQEVLQLVEL-KDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLD 158
Cdd:PRK13643  92 --FPESqlfeeTVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLaDEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLD 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686 159 EPLSALDARIRKHLREQIRQIQrELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGdaetlytAPVDVF 229
Cdd:PRK13643 170 EPTAGLDPKARIEMMQLFESIH-QSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCG-------TPSDVF 232
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 22-225 8.36e-30

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 115.99  E-value: 8.36e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  22 INCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTS----VDSGKILLDGQDIVPLSPQKRH------IGMVFQS--YALFPN 89
Cdd:PRK11022  26 ISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDypgrVMAEKLEFNGQDLQRISEKERRnlvgaeVAMIFQDpmTSLNPC 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  90 MTVEQNVAFGLRM-QKVNADDSHKRVQEVLQLVELKDLAGR---YPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD 165
Cdd:PRK11022 106 YTVGFQIMEAIKVhQGGNKKTRRQRAIDLLNQVGIPDPASRldvYPHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALD 185

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 166 ARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK11022 186 VTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAP 245
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 5-219 9.25e-30

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 112.24  E-value: 9.25e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTS--VDSGKILLDGQDIVPLSPQKRH---IGM 79
Cdd:cd03217    2 EIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKyeVTEGEILFKGEDITDLPPEERArlgIFL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNMTVEQ-----NVAFglrmqkvnaddshkrvqevlqlvelkdlagryphqmSGGQCQRVALARSLVTRPRL 154
Cdd:cd03217   82 AFQYPPEIPGVKNADflryvNEGF------------------------------------SGGEKKRNEILQLLLLEPDL 125

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 155 LLLDEPLSALDARIRKHLREQIRQIqRELGLTTIFVTHDQEEALTM-SDRIFLMNQGKIVQSGDAE 219
Cdd:cd03217  126 AILDEPDSGLDIDALRLVAEVINKL-REEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGDKE 190
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
4-226 1.09e-29

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 114.90  E-value: 1.09e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR-HIGMVFQ 82
Cdd:PRK13537   8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARqRVGVVPQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:PRK13537  88 FDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTT 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 163 ALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPV 226
Cdd:PRK13537 168 GLDPQARHLMWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIESEI 230
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 4-217 3.80e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 113.64  E-value: 3.80e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSY-AGTP----VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK---- 74
Cdd:PRK13651   3 IKVKNIVKIFnKKLPtelkALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKKKTKekek 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  75 ----------------------RHIGMVFQ--SYALFPNmTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVEL-KDLAGR 129
Cdd:PRK13651  83 vleklviqktrfkkikkikeirRRVGVVFQfaEYQLFEQ-TIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLdESYLQR 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 130 YPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDA-------RIRKHLREQirqiqrelGLTTIFVTHDQEEALTMSD 202
Cdd:PRK13651 162 SPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPqgvkeilEIFDNLNKQ--------GKTIILVTHDLDNVLEWTK 233

                        250
                 ....*....|....*
gi 545130686 203 RIFLMNQGKIVQSGD 217
Cdd:PRK13651 234 RTIFFKDGKIIKDGD 248
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
5-213 7.14e-29

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 115.89  E-value: 7.14e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLqksyAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ---KRHIGMV- 80
Cdd:COG1129  258 EVEGL----SVGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRdaiRAGIAYVp 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 --FQSYALFPNMTVEQNVAFGL-----RMQKVNADDSHKRVQEVLQLVELK-----DLAGryphQMSGGQCQRVALARSL 148
Cdd:COG1129  334 edRKGEGLVLDLSIRENITLASldrlsRGGLLDRRRERALAEEYIKRLRIKtpspeQPVG----NLSGGNQQKVVLAKWL 409

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 149 VTRPRLLLLDEPLSALD--ArirkhlREQIRQIQREL---GLTTIFVTHDQEEALTMSDRIFLMNQGKIV 213
Cdd:COG1129  410 ATDPKVLILDEPTRGIDvgA------KAEIYRLIRELaaeGKAVIVISSELPELLGLSDRILVMREGRIV 473
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
18-213 7.89e-29

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 116.75  E-value: 7.89e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  18 VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP------QKRHIGMVFQSYALFPNMT 91
Cdd:PRK10535  23 VLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDAdalaqlRREHFGFIFQRYHLLSHLT 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  92 VEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKH 171
Cdd:PRK10535 103 AAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEE 182

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 545130686 172 LREQIRQIqRELGLTTIFVTHDQEEAlTMSDRIFLMNQGKIV 213
Cdd:PRK10535 183 VMAILHQL-RDRGHTVIIVTHDPQVA-AQAERVIEIRDGEIV 222
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
34-225 1.10e-28

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 111.42  E-value: 1.10e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  34 LLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdivPL-----SPQKRHIGMVFQ--SYALFPNMTVEQNVAFGLRMQ-KV 105
Cdd:PRK15112  44 IIGENGSGKSTLAKMLAGMIEPTSGELLIDDH---PLhfgdySYRSQRIRMIFQdpSTSLNPRQRISQILDFPLRLNtDL 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 106 NADDSHKRVQEVLQLVELK-DLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELG 184
Cdd:PRK15112 121 EPEQREKQIIETLRQVGLLpDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQG 200

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 545130686 185 LTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK15112 201 ISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASP 241
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 21-225 1.28e-28

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 111.03  E-value: 1.28e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSV-----DSGKILLDGQDI----VPLSPQKRHIGMVFQSYALFPNmT 91
Cdd:PRK14243  28 NVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLipgfrVEGKVTFHGKNLyapdVDPVEVRRRIGMVFQKPNPFPK-S 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  92 VEQNVAFGLRMQ--KVNADDSHKRV--QEVLqLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDAR 167
Cdd:PRK14243 107 IYDNIAYGARINgyKGDMDELVERSlrQAAL-WDEVKDKLKQSGLSLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPI 185

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 168 IRKHLREQIRQIQRElgLTTIFVTHDQEEALTMSDRIFLMN---------QGKIVQSGDAETLYTAP 225
Cdd:PRK14243 186 STLRIEELMHELKEQ--YTIIIVTHNMQQAARVSDMTAFFNveltegggrYGYLVEFDRTEKIFNSP 250
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 5-192 1.32e-28

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 109.37  E-value: 1.32e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ-KRHIGMVFQS 83
Cdd:TIGR01189   2 AARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEpHENILYLGHL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   84 YALFPNMTVEQNVAFGLRMqkvnADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:TIGR01189  82 PGLKPELSALENLHFWAAI----HGGAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTA 157

                         170       180       190
                  ....*....|....*....|....*....|
gi 545130686  164 LDARIRKHLREQIRQ-IQRelGLTTIFVTH 192
Cdd:TIGR01189 158 LDKAGVALLAGLLRAhLAR--GGIVLLTTH 185
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 8-225 1.35e-28

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 116.11  E-value: 1.35e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   8 HLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKS----TLLRCI-AGLTSVDSGKILLD--GQDIVPLSPQK----RH 76
Cdd:PRK10261  21 AFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSvtalALMRLLeQAGGLVQCDKMLLRrrSRQVIELSEQSaaqmRH 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  77 -----IGMVFQS--YALFPNMTVEQNVAFGLRM-QKVNADDS---HKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALA 145
Cdd:PRK10261 101 vrgadMAMIFQEpmTSLNPVFTVGEQIAESIRLhQGASREEAmveAKRMLDQVRIPEAQTILSRYPHQLSGGMRQRVMIA 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 146 RSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK10261 181 MALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAP 260
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 13-225 1.73e-28

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 110.56  E-value: 1.73e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  13 YAGTPVFSDINCEVAKGEFVTLLGPSGCGKStlLRCIAGL------TSVDSGKILLDGQDIVPLSPQKRHIGMVFQS--Y 84
Cdd:PRK10418  13 QAAQPLVHGVSLTLQRGRVLALVGGSGSGKS--LTCAAALgilpagVRQTAGRVLLDGKPVAPCALRGRKIATIMQNprS 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  85 ALFPNMTVEQNVAFGLRMQKVNADDShkRVQEVLQLVELKD---LAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:PRK10418  91 AFNPLHTMHTHARETCLALGKPADDA--TLTAALEAVGLENaarVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPT 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 162 SALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK10418 169 TDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAP 232
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
7-224 2.99e-28

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 110.46  E-value: 2.99e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   7 QHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHIGMVFQSY 84
Cdd:PRK10253  11 EQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEvaRRIGLLAQNA 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  85 ALFPNMTVEQNVAFG--------LRMQKVNADdshkRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:PRK10253  91 TTPGDITVQELVARGryphqplfTRWRKEDEE----AVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIML 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTA 224
Cdd:PRK10253 167 LDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTA 234
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 4-192 5.89e-28

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 113.75  E-value: 5.89e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQ-KSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILL-DGQDIVPLsPQKrhigmvf 81
Cdd:COG4178  363 LALEDLTlRTPDGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARpAGARVLFL-PQR------- 434

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 qSYalFPNMTveqnvafgLRMQ----KVNADDSHKRVQEVLQLVELKDLAGRY------PHQMSGGQCQRVALARSLVTR 151
Cdd:COG4178  435 -PY--LPLGT--------LREAllypATAEAFSDAELREALEAVGLGHLAERLdeeadwDQVLSLGEQQRLAFARLLLHK 503

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 545130686 152 PRLLLLDEPLSALDARIRKHLREQIRqiQRELGLTTIFVTH 192
Cdd:COG4178  504 PDWLFLDEATSALDEENEAALYQLLR--EELPGTTVISVGH 542
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1-218 7.94e-28

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 108.43  E-value: 7.94e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK---RHI 77
Cdd:PRK11614   3 KVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKimrEAV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVFQSYALFPNMTVEQNVAFGLRMqkVNADDSHKRVQEVLQLV-ELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLL 156
Cdd:PRK11614  83 AIVPEGRRVFSRMTVEENLAMGGFF--AERDQFQERIKWVYELFpRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIqRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIV--QSGDA 218
Cdd:PRK11614 161 LDEPSLGLAPIIIQQIFDTIEQL-REQGMTIFLVEQNANQALKLADRGYVLENGHVVleDTGDA 223
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
2-219 8.75e-28

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 108.95  E-value: 8.75e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   2 SFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSG----------KILLDGQDIVPLS 71
Cdd:PRK09984   3 TIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSagshiellgrTVQREGRLARDIR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  72 PQKRHIGMVFQSYALFPNMTVEQNVAFGL---------------RMQKvnaddshKRVQEVLQLVELKDLAGRYPHQMSG 136
Cdd:PRK09984  83 KSRANTGYIFQQFNLVNRLSVLENVLIGAlgstpfwrtcfswftREQK-------QRALQALTRVGMVHFAHQRVSTLSG 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 137 GQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:PRK09984 156 GQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDG 235


                 ...
gi 545130686 217 DAE 219
Cdd:PRK09984 236 SSQ 238
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 5-221 1.99e-27

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 111.66  E-value: 1.99e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQ-KSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP-QKRHIGMVF- 81
Cdd:COG3845  259 EVENLSvRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPrERRRLGVAYi 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 ----QSYALFPNMTVEQNVAFGLRMQKVNAD----DSHKRVQEVLQLVELKDLAGRYPHQ----MSGGQCQRVALARSLV 149
Cdd:COG3845  339 pedrLGRGLVPDMSVAENLILGRYRRPPFSRggflDRKAIRAFAEELIEEFDVRTPGPDTparsLSGGNQQKVILARELS 418

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 150 TRPRLLLLDEPLSALD----ARIRKHLREqirqiQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:COG3845  419 RDPKLLIAAQPTRGLDvgaiEFIHQRLLE-----LRDAGAAVLLISEDLDEILALSDRIAVMYEGRIVGEVPAAEA 489
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 4-221 5.20e-27

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 111.37  E-value: 5.20e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    4 VSVQHLQKSYA-GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMV 80
Cdd:TIGR01193 474 IVINDVSYSYGyGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHtlRQFINYL 553

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   81 FQSYALFPNmTVEQNVAFGLRmQKVNADDshkrVQEVLQLVELKDLAGRYPH-----------QMSGGQCQRVALARSLV 149
Cdd:TIGR01193 554 PQEPYIFSG-SILENLLLGAK-ENVSQDE----IWAACEIAEIKDDIENMPLgyqtelseegsSISGGQKQRIALARALL 627

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 545130686  150 TRPRLLLLDEPLSALDARIRKHLREQIRQIQRElglTTIFVTHDQEEAlTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:TIGR01193 628 TDSKVLILDESTSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLSVA-KQSDKIIVLDHGKIIEQGSHDEL 695
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 1-243 5.37e-27

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 108.27  E-value: 5.37e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYaGTP-----VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVD---SGKILLDGQDIVPLsP 72
Cdd:PRK09473  10 DALLDVKDLRVTF-STPdgdvtAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANgriGGSATFNGREILNL-P 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  73 QKR-------HIGMVFQS--YALFPNMTVEQNVAFGL----RMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQC 139
Cdd:PRK09473  88 EKElnklraeQISMIFQDpmTSLNPYMRVGEQLMEVLmlhkGMSKAEAFEESVRMLDAVKMPEARKRMKMYPHEFSGGMR 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 140 QRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAE 219
Cdd:PRK09473 168 QRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNAR 247

                        250       260
                 ....*....|....*....|....
gi 545130686 220 TLYTAPVDVFAAGFIGNYNLLDAD 243
Cdd:PRK09473 248 DVFYQPSHPYSIGLLNAVPRLDAE 271
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 5-216 5.55e-27

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 105.88  E-value: 5.55e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQK-SYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGqdIVPLSPQKRH---IGMV 80
Cdd:cd03267   22 SLKSLFKrKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAG--LVPWKRRKKFlrrIGVV 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 F-QSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDE 159
Cdd:cd03267  100 FgQKTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDE 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 160 PLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03267  180 PTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
13-232 5.56e-27

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 107.02  E-value: 5.56e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  13 YAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdivPLSPQKR-------HIGMVFQSya 85
Cdd:PRK13638  11 YQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGK---PLDYSKRgllalrqQVATVFQD-- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  86 lfPNMTV-----EQNVAFGLRMQKVNADDSHKRVQEVLQLVElkdlAGRYPHQ----MSGGQCQRVALARSLVTRPRLLL 156
Cdd:PRK13638  86 --PEQQIfytdiDSDIAFSLRNLGVPEAEITRRVDEALTLVD----AQHFRHQpiqcLSHGQKKRVAIAGALVLQARYLL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 157 LDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDaetlytaPVDVFAAG 232
Cdd:PRK13638 160 LDEPTAGLDPAGRTQMIAIIRRIVAQ-GNHVIISSHDIDLIYEISDAVYVLRQGQILTHGA-------PGEVFACT 227
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 6-193 6.14e-27

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 110.53  E-value: 6.14e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    6 VQHLQKSYAGTP-VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGMVFQ 82
Cdd:TIGR02868 337 LRDLSAGYPGAPpVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVssLDQDEVRRRVSVCAQ 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   83 SYALFpNMTVEQNVAFGlrmqkvNADDSHKRVQEVLQLVELKDLAGRYPHQM-----------SGGQCQRVALARSLVTR 151
Cdd:TIGR02868 417 DAHLF-DTTVRENLRLA------RPDATDEELWAALERVGLADWLRALPDGLdtvlgeggarlSGGERQRLALARALLAD 489

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 545130686  152 PRLLLLDEPLSALDARIRKHLREQIRQIQRelGLTTIFVTHD 193
Cdd:TIGR02868 490 APILLLDEPTEHLDAETADELLEDLLAALS--GRTVVLITHH 529
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 17-225 1.18e-26

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 109.79  E-value: 1.18e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  17 PVFSDINCEVAKGEFVTLLGPSGCGKS-TLLRCIAGLTS----VDSGKILLDGQDIVPLSPQK-RH-----IGMVFQS-- 83
Cdd:PRK15134  23 TVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSppvvYPSGDIRFHGESLLHASEQTlRGvrgnkIAMIFQEpm 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YALFPNMTVEQNVAFGLRMQK-VNADDSHKRVQEVLQLVELKDLAGR---YPHQMSGGQCQRVALARSLVTRPRLLLLDE 159
Cdd:PRK15134 103 VSLNPLHTLEKQLYEVLSLHRgMRREAARGEILNCLDRVGIRQAAKRltdYPHQLSGGERQRVMIAMALLTRPELLIADE 182

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 160 PLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK15134 183 PTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAP 248
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
17-192 1.21e-26

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 104.12  E-value: 1.21e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIvplspqkRHIGMVFQSYALF--------P 88
Cdd:PRK13538  15 ILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPI-------RRQRDEYHQDLLYlghqpgikT 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  89 NMTVEQNVAFGLRMQKVNADDshkRVQEVLQLVelkDLAGR--YP-HQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD 165
Cdd:PRK13538  88 ELTALENLRFYQRLHGPGDDE---ALWEALAQV---GLAGFedVPvRQLSAGQQRRVALARLWLTRAPLWILDEPFTAID 161

                        170       180       190
                 ....*....|....*....|....*....|.
gi 545130686 166 ----ARIRKHLREQIRQiqrelGLTTIFVTH 192
Cdd:PRK13538 162 kqgvARLEALLAQHAEQ-----GGMVILTTH 187
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 4-225 1.47e-26

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 106.86  E-value: 1.47e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHL-----QKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSG-----------KILLDGQDI 67
Cdd:PRK13631  22 LRVKNLycvfdEKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGtiqvgdiyigdKKNNHELIT 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  68 VPLSPQ-------KRHIGMVFQ--SYALFPNmTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKD-LAGRYPHQMSGG 137
Cdd:PRK13631 102 NPYSKKiknfkelRRRVSMVFQfpEYQLFKD-TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLDDsYLERSPFGLSGG 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 138 QCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGD 217
Cdd:PRK13631 181 QKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKAN-NKTVFVITHTMEHVLEVADEVIVMDKGKILKTGT 259


                 ....*...
gi 545130686 218 AETLYTAP 225
Cdd:PRK13631 260 PYEIFTDQ 267
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 4-216 2.95e-26

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 102.39  E-value: 2.95e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAG--TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRH-IGMV 80
Cdd:cd03247    1 LSINNVSFSYPEqeQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKALSSlISVL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFpNMTVEQNVafglrmqkvnaddshkrvqevlqlvelkdlaGRyphQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:cd03247   81 NQRPYLF-DTTLRNNL-------------------------------GR---RFSGGERQRLALARILLQDAPIVLLDEP 125

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 161 LSALDARIRKHLREQIRQIQRElgLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03247  126 TVGLDPITERQLLSLIFEVLKD--KTLIWITH-HLTGIEHMDKILFLENGKIIMQG 178
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 1-225 3.90e-26

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 104.04  E-value: 3.90e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGmv 80
Cdd:PRK09544   2 TSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLRIGYVPQKLYLD-- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 fqsyALFPnMTVEQNVAFGLRMQKVNADDSHKRVQEVlQLVElkdlagrYPHQ-MSGGQCQRVALARSLVTRPRLLLLDE 159
Cdd:PRK09544  80 ----TTLP-LTVNRFLRLRPGTKKEDILPALKRVQAG-HLID-------APMQkLSGGETQRVLLARALLNRPQLLVLDE 146

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 160 PLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQgKIVQSGDAETLYTAP 225
Cdd:PRK09544 147 PTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEVLCLNH-HICCSGTPEVVSLHP 211
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 21-221 5.80e-26

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 105.17  E-value: 5.80e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGqdivpLSPQK------RHIGMVF-QSYALFPNMTVE 93
Cdd:COG4586   40 DISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLG-----YVPFKrrkefaRRIGVVFgQRSQLWWDLPAI 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  94 QNvaFGL--RMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKH 171
Cdd:COG4586  115 DS--FRLlkAIYRIPDAEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEA 192

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 545130686 172 LREQIRQIQRELGlTTIFVT-HDQE--EALtmSDRIFLMNQGKIVQSGDAETL 221
Cdd:COG4586  193 IREFLKEYNRERG-TTILLTsHDMDdiEAL--CDRVIVIDHGRIIYDGSLEEL 242
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 15-173 8.01e-26

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 102.26  E-value: 8.01e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  15 GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSP--QKRHIGmvfQSYALFPNMTV 92
Cdd:PRK13539  14 GRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVaeACHYLG---HRNAMKPALTV 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  93 EQNVAFGLRMQkvNADDSHkrVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDAR----- 167
Cdd:PRK13539  91 AENLEFWAAFL--GGEELD--IAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAavalf 166


                 ....*....
gi 545130686 168 ---IRKHLR 173
Cdd:PRK13539 167 aelIRAHLA 175
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 4-216 3.46e-25

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 100.65  E-value: 3.46e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGT--PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGM 79
Cdd:cd03244    3 IEFKNVSLRYRPNlpPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDIskIGLHDLRSRISI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNmTVEQNVA-FGLrmqkvnADDShkRVQEVLQLVELKDLAGRYPHQM-----------SGGQCQRVALARS 147
Cdd:cd03244   83 IPQDPVLFSG-TIRSNLDpFGE------YSDE--ELWQALERVGLKEFVESLPGGLdtvveeggenlSVGQRQLLCLARA 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545130686 148 LVTRPRLLLLDEPLSALD----ARIRKHLREQIRQIqrelglTTIFVTHdQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03244  154 LLRKSKILVLDEATASVDpetdALIQKTIREAFKDC------TVLTIAH-RLDTIIDSDRILVLDKGRVVEFD 219
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 6-193 3.61e-25

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 105.53  E-value: 3.61e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILldgqdivpLSPQKRhIGMVFQSYA 85
Cdd:COG0488    1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVS--------IPKGLR-IGYLPQEPP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  86 LFPNMTVEQNVAFGL--------RMQKVNA-----DDSHKRVQEVLQLVELKD----------------LAGRYPHQ--- 133
Cdd:COG0488   72 LDDDLTVLDTVLDGDaelraleaELEELEAklaepDEDLERLAELQEEFEALGgweaearaeeilsglgFPEEDLDRpvs 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686 134 -MSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRelglTTIFVTHD 193
Cdd:COG0488  152 eLSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKNYPG----TVLVVSHD 208
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
4-216 4.26e-25

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 105.43  E-value: 4.26e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGT-PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGMV 80
Cdd:PRK13657 335 VEFDDVSFSYDNSrQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIrtVTRASLRRNIAVV 414

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFpNMTVEQNvafgLRMQKVNADDSH-----KRVQeVLQLVELKD-----LAGRYPHQMSGGQCQRVALARSLVT 150
Cdd:PRK13657 415 FQDAGLF-NRSIEDN----IRVGRPDATDEEmraaaERAQ-AHDFIERKPdgydtVVGERGRQLSGGERQRLAIARALLK 488

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 151 RPRLLLLDEPLSALDARIRKHLREQIRQIQRelGLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:PRK13657 489 DPPILILDEATSALDVETEAKVKAALDELMK--GRTTFIIAH-RLSTVRNADRILVFDNGRVVESG 551
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
29-225 9.49e-25

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 102.29  E-value: 9.49e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  29 GEFVTLLGPSGCGKSTLLRCIAGLTS----VDSGKILLDGQDIVPLSPQKRH------IGMVFQ--SYALFPNMTVEQNV 96
Cdd:COG4170   33 GEIRGLVGESGSGKSLIAKAICGITKdnwhVTADRFRWNGIDLLKLSPRERRkiigreIAMIFQepSSCLDPSAKIGDQL 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  97 AF--------GLRMQKVNAddSHKRVQEVLQLVELKD---LAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD 165
Cdd:COG4170  113 IEaipswtfkGKWWQRFKW--RKKRAIELLHRVGIKDhkdIMNSYPHELTEGECQKVMIAMAIANQPRLLIADEPTNAME 190

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 166 ----ARIRKhLREQIRQIQrelGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:COG4170  191 sttqAQIFR-LLARLNQLQ---GTSILLISHDLESISQWADTITVLYCGQTVESGPTEQILKSP 250
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 21-217 1.45e-24

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 103.54  E-value: 1.45e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR-HIGMVFQSY-----ALFPNMTVEQ 94
Cdd:PRK10762 270 DVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGlANGIVYISEdrkrdGLVLGMSVKE 349

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  95 NVA------FGLRMQKVNADDSHKRVQEVLQLVELKDlagryPHQ------MSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:PRK10762 350 NMSltalryFSRAGGSLKHADEQQAVSDFIRLFNIKT-----PSMeqaiglLSGGNQQKVAIARGLMTRPKVLILDEPTR 424

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 163 ALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIvqSGD 217
Cdd:PRK10762 425 GVDVGAKKEIYQLINQFKAE-GLSIILVSSEMPEVLGMSDRILVMHEGRI--SGE 476
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 4-233 3.79e-24

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 102.57  E-value: 3.79e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSV--DSGKIL----------------LDGQ 65
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQYepTSGRIIyhvalcekcgyverpsKVGE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   66 --------------DIVPLSPQ-----KRHIGMVFQ-SYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKD 125
Cdd:TIGR03269  81 pcpvcggtlepeevDFWNLSDKlrrriRKRIAIMLQrTFALYGDDTVLDNVLEALEEIGYEGKEAVGRAVDLIEMVQLSH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  126 LAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIF 205
Cdd:TIGR03269 161 RITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAI 240

                         250       260
                  ....*....|....*....|....*...
gi 545130686  206 LMNQGKIVQSGDAETLytapVDVFAAGF 233
Cdd:TIGR03269 241 WLENGEIKEEGTPDEV----VAVFMEGV 264
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
29-226 4.20e-24

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 99.09  E-value: 4.20e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  29 GEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFPNMTVEQNVAFGL-----R 101
Cdd:PRK10575  37 GKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKafARKVAYLPQQLPAAEGMTVRELVAIGRypwhgA 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 102 MQKVNADDsHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQR 181
Cdd:PRK10575 117 LGRFGAAD-REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQ 195

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 545130686 182 ELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPV 226
Cdd:PRK10575 196 ERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGET 240
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 4-221 1.29e-23

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 101.05  E-value: 1.29e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDS--GKILLDGQDIVPLS---PQKRHIG 78
Cdd:TIGR02633   2 LEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTwdGEIYWSGSPLKASNirdTERAGIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   79 MVFQSYALFPNMTVEQNVAFG----LRMQKVNADDSHKRVQEVLQLVELKDL-AGRYPHQMSGGQCQRVALARSLVTRPR 153
Cdd:TIGR02633  82 IIHQELTLVPELSVAENIFLGneitLPGGRMAYNAMYLRAKNLLRELQLDADnVTRPVGDYGGGQQQLVEIAKALNKQAR 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686  154 LLLLDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:TIGR02633 162 LLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQHVATKDMSTM 228
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
4-224 4.43e-23

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 99.79  E-value: 4.43e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSY-AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMV 80
Cdd:PRK10790 341 IDIDNVSFAYrDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSvlRQGVAMV 420

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNmTVEQNVAFGlrmqkvnADDSHKRVQEVLQLVELKDLAGRYP-----------HQMSGGQCQRVALARSLV 149
Cdd:PRK10790 421 QQDPVVLAD-TFLANVTLG-------RDISEEQVWQALETVQLAELARSLPdglytplgeqgNNLSVGQKQLLALARVLV 492

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 150 TRPRLLLLDEPLSALDARIRKHLREQIRQIQRElglTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTA 224
Cdd:PRK10790 493 QTPQILILDEATANIDSGTEQAIQQALAAVREH---TTLVVIAHRLSTIVEADTILVLHRGQAVEQGTHQQLLAA 564
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 4-211 9.07e-23

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 92.13  E-value: 9.07e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDgqdivplspqkrhigmvfqs 83
Cdd:cd03221    1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWG-------------------- 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 yalfpnmtveQNVAFGlrmqkvnaddshkrvqevlqlvelkdlagrYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:cd03221   61 ----------STVKIG------------------------------YFEQLSGGEKMRLALAKLLLENPNLLLLDEPTNH 100

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 545130686 164 LDARIRKHLREQIRQIQRELglttIFVTHDQEEALTMSDRIFLMNQGK 211
Cdd:cd03221  101 LDLESIEALEEALKEYPGTV----ILVSHDRYFLDQVATKIIELEDGK 144
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
17-225 1.43e-22

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 98.25  E-value: 1.43e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGMVFQSYALFPNmTVEQ 94
Cdd:PRK10789 329 PALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLtkLQLDSWRSRLAVVSQTPFLFSD-TVAN 407

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  95 NVAFGlrmqkvNADDSHKRVQEVLQLVELKDLAGRYPH-----------QMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:PRK10789 408 NIALG------RPDATQQEIEHVARLASVHDDILRLPQgydtevgergvMLSGGQKQRISIARALLLNAEILILDDALSA 481

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 545130686 164 LDARIRKHLREQIRQIQRElglTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK10789 482 VDGRTEHQILHNLRQWGEG---RTVIISAHRLSALTEASEILVMQHGHIAQRGNHDQLAQQS 540
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 10-216 1.50e-22

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 93.10  E-value: 1.50e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  10 QKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVD---SGKILLDGQDIVP-LSPQKRHIGMVFQSYA 85
Cdd:cd03233   14 GKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEfAEKYPGEIIYVSEEDV 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  86 LFPNMTVEQNVAFGLRMQkvnaddshkrvqevlqlvelkdlAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD 165
Cdd:cd03233   94 HFPTLTVRETLDFALRCK-----------------------GNEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLD 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 545130686 166 ARIRKHLREQIRQIQRELGLTTIF-VTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03233  151 SSTALEILKCIRTMADVLKTTTFVsLYQASDEIYDLFDKVLVLYEGRQIYYG 202
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 18-192 2.20e-22

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 92.94  E-value: 2.20e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  18 VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ-KRHIGMVFQSYALFPNMTVEQNV 96
Cdd:cd03231   15 LFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSiARGLLYLGHAPGIKTTLSVLENL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  97 AFglrmqkVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQI 176
Cdd:cd03231   95 RF------WHADHSDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAM 168

                        170
                 ....*....|....*.
gi 545130686 177 RQiQRELGLTTIFVTH 192
Cdd:cd03231  169 AG-HCARGGMVVLTTH 183
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 4-213 2.70e-22

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 97.06  E-value: 2.70e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLdGQDIvplspqkrHIGMVFQS 83
Cdd:COG0488  316 LELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETV--------KIGYFDQH 386

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YALF-PNMTVEQNV---AFGLRMQKVNA---------DDSHKRVqevlqlvelKDLagryphqmSGGQCQRVALARSLVT 150
Cdd:COG0488  387 QEELdPDKTVLDELrdgAPGGTEQEVRGylgrflfsgDDAFKPV---------GVL--------SGGEKARLALAKLLLS 449

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 151 RPRLLLLDEPLSALDArirkHLREQIrqiqrELGL-----TTIFVTHDQE--EALTmsDRIFLMNQGKIV 213
Cdd:COG0488  450 PPNVLLLDEPTNHLDI----ETLEAL-----EEALddfpgTVLLVSHDRYflDRVA--TRILEFEDGGVR 508
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 8-216 1.10e-21

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 95.50  E-value: 1.10e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    8 HLQKSYAGtpvfsdinceVAK-GEFVTLLGPSGCGKSTLLRCIAGLTSVD---SGKILLDGQDIvPLSPQKRHIGMVFQS 83
Cdd:TIGR00955  39 HLLKNVSG----------VAKpGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGMPI-DAKEMRAISAYVQQD 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   84 YALFPNMTVEQNVAFG--LRMQK-VNADDSHKRVQEVLQLVELKDLA-------GRYpHQMSGGQCQRVALARSLVTRPR 153
Cdd:TIGR00955 108 DLFIPTLTVREHLMFQahLRMPRrVTKKEKRERVDEVLQALGLRKCAntrigvpGRV-KGLSGGERKRLAFASELLTDPP 186

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686  154 LLLLDEPLSALDArirkHLREQIRQIQREL---GLTTIFVTHD-QEEALTMSDRIFLMNQGKIVQSG 216
Cdd:TIGR00955 187 LLFCDEPTSGLDS----FMAYSVVQVLKGLaqkGKTIICTIHQpSSELFELFDKIILMAEGRVAYLG 249
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
3-217 1.14e-21

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 95.24  E-value: 1.14e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   3 FVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ---KRHIGM 79
Cdd:PRK09700   5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKlaaQLGIGI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNMTVEQNVAFGLRMQK----VNADDSHK---RVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRP 152
Cdd:PRK09700  85 IYQELSVIDELTVLENLYIGRHLTKkvcgVNIIDWREmrvRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDA 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 153 RLLLLDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGD 217
Cdd:PRK09700 165 KVIIMDEPTSSLTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGM 228
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 7-221 1.26e-21

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 95.00  E-value: 1.26e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   7 QHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDS--GKILLDGQDIVPLS---PQKRHIGMVF 81
Cdd:PRK13549   9 KNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGTyeGEIIFEGEELQASNirdTERAGIAIIH 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 QSYALFPNMTVEQNVAFG---LRMQKVNADDSHKRVQEVLQLVELK-DLAGRYPHqMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:PRK13549  89 QELALVKELSVLENIFLGneiTPGGIMDYDAMYLRAQKLLAQLKLDiNPATPVGN-LGLGQQQLVEIAKALNKQARLLIL 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545130686 158 DEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:PRK13549 168 DEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGRHIGTRPAAGM 230
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 4-216 4.57e-21

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 94.31  E-value: 4.57e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686     4 VSVQHLQKSY--AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI-VPLSPQKRHIGMV 80
Cdd:TIGR01257  929 VCVKNLVKIFepSGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIeTNLDAVRQSLGMC 1008

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    81 FQSYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:TIGR01257 1009 PQHNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEP 1088

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686   161 LSALDARIRKHLREQIrqIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:TIGR01257 1089 TSGVDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSG 1142
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 17-221 5.39e-21

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 93.86  E-value: 5.39e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdiVPLSPQKrhigmvfqsyALFPNMTVEQNV 96
Cdd:TIGR00957  652 PTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS--VAYVPQQ----------AWIQNDSLRENI 719

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    97 AFGLRMQKvnaddshKRVQEVLQ----LVELKDLA-------GRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD 165
Cdd:TIGR00957  720 LFGKALNE-------KYYQQVLEacalLPDLEILPsgdrteiGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVD 792

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686   166 ARIRKHLREQIRQIQREL-GLTTIFVTHDQeEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:TIGR00957  793 AHVGKHIFEHVIGPEGVLkNKTRILVTHGI-SYLPQVDVIIVMSGGKISEMGSYQEL 848
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
4-221 5.52e-21

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 93.54  E-value: 5.52e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAG--TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGM 79
Cdd:PRK11176 342 IEFRNVTFTYPGkeVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLrdYTLASLRNQVAL 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFpNMTVEQNVAFGlrmqkvnADDSHKR--VQEVLQLVELKDLAGRYPH-----------QMSGGQCQRVALAR 146
Cdd:PRK11176 422 VSQNVHLF-NDTIANNIAYA-------RTEQYSReqIEEAARMAYAMDFINKMDNgldtvigengvLLSGGQRQRIAIAR 493

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545130686 147 SLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRElglTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:PRK11176 494 ALLRDSPILILDEATSALDTESERAIQAALDELQKN---RTSLVIAHRLSTIEKADEILVVEDGEIVERGTHAEL 565
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 16-212 5.71e-21

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 89.45  E-value: 5.71e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  16 TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIvplsPQKRH------IGMVFQSYALFPN 89
Cdd:cd03248   27 TLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPI----SQYEHkylhskVSLVGQEPVLFAR 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  90 mTVEQNVAFGLR---MQKVNADDSHKRVQEVLQLVEL--KDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSAL 164
Cdd:cd03248  103 -SLQDNIAYGLQscsFECVKEAAQKAHAHSFISELASgyDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSAL 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 545130686 165 DARIRKHLREQIRQIQRElglTTIFVTHDQEEALTMSDRIFLMNQGKI 212
Cdd:cd03248  182 DAESEQQVQQALYDWPER---RTVLVIAHRLSTVERADQILVLDGGRI 226
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
21-221 7.31e-21

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 93.27  E-value: 7.31e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP--LSPQKRhIGMVFQSYALFPNMTVEQNVAF 98
Cdd:NF033858 284 HVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAgdIATRRR-VGYMSQAFSLYGELTVRQNLEL 362

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  99 GLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQ 178
Cdd:NF033858 363 HARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIE 442

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 545130686 179 IQRELGLtTIFV-THDQEEALTmSDRIFLMNQGK---------IVQSGDAETL 221
Cdd:NF033858 443 LSREDGV-TIFIsTHFMNEAER-CDRISLMHAGRvlasdtpaaLVAARGAATL 493
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
22-225 1.48e-20

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 90.63  E-value: 1.48e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  22 INCEVAKGEFVTLLGPSGCGKSTLLRCIAGLT----SVDSGKILLDGQDIVPLSPQKRH------IGMVFQ--SYALFPN 89
Cdd:PRK15093  26 VSMTLTEGEIRGLVGESGSGKSLIAKAICGVTkdnwRVTADRMRFDDIDLLRLSPRERRklvghnVSMIFQepQSCLDPS 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  90 MTVEQNVA--------FGLRMQKVNAddSHKRVQEVLQLVELKD---LAGRYPHQMSGGQCQRVALARSLVTRPRLLLLD 158
Cdd:PRK15093 106 ERVGRQLMqnipgwtyKGRWWQRFGW--RKRRAIELLHRVGIKDhkdAMRSFPYELTEGECQKVMIAIALANQPRLLIAD 183

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 159 EPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PRK15093 184 EPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTTP 250
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 14-210 2.48e-20

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 87.77  E-value: 2.48e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  14 AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKI-----LLDGQDIVPLSPQKRH-IGMVFQSYALF 87
Cdd:cd03290   12 SGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVhwsnkNESEPSFEATRSRNRYsVAYAAQKPWLL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  88 pNMTVEQNVAFG--LRMQKVNADDSHKRVQEVLQLVELKDLA--GRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:cd03290   92 -NATVEENITFGspFNKQRYKAVTDACSLQPDIDLLPFGDQTeiGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSA 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 545130686 164 LDARIRKHL-REQIRQIQRELGLTTIFVTHdQEEALTMSDRIFLMNQG 210
Cdd:cd03290  171 LDIHLSDHLmQEGILKFLQDDKRTLVLVTH-KLQYLPHADWIIAMKDG 217
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 19-215 5.15e-20

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 90.50  E-value: 5.15e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  19 FSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKR-HIGMVF-----QSYALFPNMTV 92
Cdd:PRK15439 279 FRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQRlARGLVYlpedrQSSGLYLDAPL 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  93 EQNV--------AFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRyphqMSGGQCQRVALARSLVTRPRLLLLDEPLSAL 164
Cdd:PRK15439 359 AWNVcalthnrrGFWIKPARENAVLERYRRALNIKFNHAEQAART----LSGGNQQKVLIAKCLEASPQLLIVDEPTRGV 434

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 545130686 165 DARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQS 215
Cdd:PRK15439 435 DVSARNDIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLVMHQGEISGA 484
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 4-216 5.94e-20

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 86.31  E-value: 5.94e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAG--TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGM 79
Cdd:cd03369    7 IEVENLSVRYAPdlPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDIstIPLEDLRSSLTI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNmTVEQNVafglrmqKVNADDSHKRVQEVLQLVELKDlagryphQMSGGQCQRVALARSLVTRPRLLLLDE 159
Cdd:cd03369   87 IPQDPTLFSG-TIRSNL-------DPFDEYSDEEIYGALRVSEGGL-------NLSQGQRQLLCLARALLKRPRVLVLDE 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686 160 PLSAL----DARIRKHLREqirqiqrELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSG 216
Cdd:cd03369  152 ATASIdyatDALIQKTIRE-------EFTNSTILTIAHRLRTIIDYDKILVMDAGEVKEYD 205
hmuV PRK13547
heme ABC transporter ATP-binding protein;
4-234 3.49e-19

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 85.65  E-value: 3.49e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAG-LTSVD-------SGKILLDGQDIVPLSPQK- 74
Cdd:PRK13547   2 LTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGdLTGGGaprgarvTGDVTLNGEPLAAIDAPRl 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  75 --RHIGMVFQSYALFPnMTVEQNVAFGLRMQKVNADDSHKRVQEV----LQLVELKDLAGRYPHQMSGGQCQRVALARSL 148
Cdd:PRK13547  82 arLRAVLPQAAQPAFA-FSAREIVLLGRYPHARRAGALTHRDGEIawqaLALAGATALVGRDVTTLSGGELARVQFARVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 149 ---------VTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGdae 219
Cdd:PRK13547 161 aqlwpphdaAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHG--- 237

                        250
                 ....*....|....*
gi 545130686 220 tlytAPVDVFAAGFI 234
Cdd:PRK13547 238 ----APADVLTPAHI 248
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
21-214 8.32e-19

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 86.76  E-value: 8.32e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ---KRHIGMVFQSY---ALFPNMTVEQ 94
Cdd:PRK09700 281 DISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLdavKKGMAYITESRrdnGFFPNFSIAQ 360

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  95 NVA---------FGLRMQKVNADDSHKRVQEVLQLVELK-DLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSAL 164
Cdd:PRK09700 361 NMAisrslkdggYKGAMGLFHEVDEQRTAENQRELLALKcHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGI 440

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 545130686 165 DARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQ 214
Cdd:PRK09700 441 DVGAKAEIYKVMRQLADD-GKVILMVSSELPEIITVCDRIAVFCEGRLTQ 489
PLN03130 PLN03130
ABC transporter C family member; Provisional
 12-221 1.05e-18

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 87.10  E-value: 1.05e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   12 SYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAG-LTSVDSGKILLDGQdiVPLSPQkrhIGMVFqsyalfpNM 90
Cdd:PLN03130  626 SKAERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGeLPPRSDASVVIRGT--VAYVPQ---VSWIF-------NA 693

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   91 TVEQNVAFGLRMQKvnadDSHKRVQEV------LQLVELKDLA--GRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:PLN03130  694 TVRDNILFGSPFDP----ERYERAIDVtalqhdLDLLPGGDLTeiGERGVNISGGQKQRVSMARAVYSNSDVYIFDDPLS 769

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686  163 ALDArirkHLREQI--RQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:PLN03130  770 ALDA----HVGRQVfdKCIKDELRGKTRVLVTNQLHFLSQVDRIILVHEGMIKEEGTYEEL 826
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 4-202 1.69e-18

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 82.31  E-value: 1.69e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP-LSPQKRHIGMVFQ 82
Cdd:PRK13540   2 LDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKdLCTYQKQLCFVGH 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SYALFPNMTVEQNVAFGLRMQKVNADdshkrVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:PRK13540  82 RSGINPYLTLRENCLYDIHFSPGAVG-----ITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLV 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 545130686 163 ALDARIRKHLREQIRQIQRELGltTIFVTHDQEEALTMSD 202
Cdd:PRK13540 157 ALDELSLLTIITKIQEHRAKGG--AVLLTSHQDLPLNKAD 194
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
1-218 2.02e-18

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 85.73  E-value: 2.02e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdivplsPQK------ 74
Cdd:PRK11288   2 SPYLSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQ------EMRfastta 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  75 ---RHIGMVFQSYALFPNMTVEQNVAFGL---RMQKVNADDSHKRVQEVLQ--------LVELKDLagryphqmSGGQCQ 140
Cdd:PRK11288  76 alaAGVAIIYQELHLVPEMTVAENLYLGQlphKGGIVNRRLLNYEAREQLEhlgvdidpDTPLKYL--------SIGQRQ 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 141 RVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDA 218
Cdd:PRK11288 148 MVEIAKALARNARVIAFDEPTSSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRYVATFDD 224
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 14-192 2.16e-18

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 81.05  E-value: 2.16e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  14 AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLdgqdivplsPQKRHIGMVFQ-SYalFPNMTv 92
Cdd:cd03223   12 DGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGM---------PEGEDLLFLPQrPY--LPLGT- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  93 eqnvafgLRmqkvnaddshkrvqEVLqlvelkdlagRYP--HQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRK 170
Cdd:cd03223   80 -------LR--------------EQL----------IYPwdDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESED 128

                        170       180
                 ....*....|....*....|..
gi 545130686 171 HLREQIrqiqRELGLTTIFVTH 192
Cdd:cd03223  129 RLYQLL----KELGITVISVGH 146
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 1-213 4.58e-18

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 85.00  E-value: 4.58e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   1 MSFVSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDgQDIVPLSPQK---RHI 77
Cdd:PRK11147   1 MSLISIHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYE-QDLIVARLQQdppRNV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 -GMVF---------------QSYALFPNMTVEQNVAFGLRMQKVNADDSH-------KRVQEVLQLVEL---KDLAgryp 131
Cdd:PRK11147  80 eGTVYdfvaegieeqaeylkRYHDISHLVETDPSEKNLNELAKLQEQLDHhnlwqleNRINEVLAQLGLdpdAALS---- 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 132 hQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD-ARIrkhlrEQIRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQG 210
Cdd:PRK11147 156 -SLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDiETI-----EWLEGFLKTFQGSIIFISHDRSFIRNMATRIVDLDRG 229


                 ...
gi 545130686 211 KIV 213
Cdd:PRK11147 230 KLV 232
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 5-208 2.35e-17

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 82.68  E-value: 2.35e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    5 SVQHLQKSYAGT-PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLdgqdivplSPQKRhIGMVFQS 83
Cdd:TIGR03719   6 TMNRVSKVVPPKkEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARP--------QPGIK-VGYLPQE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   84 YALFPNMTVEQNVAFGL--------RMQKVNA------DDSHK------RVQEVLQLVELKDL---------AGRYP--- 131
Cdd:TIGR03719  77 PQLDPTKTVRENVEEGVaeikdaldRFNEISAkyaepdADFDKlaaeqaELQEIIDAADAWDLdsqleiamdALRCPpwd 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  132 ---HQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDArirkhlrEQIRQIQREL----GlTTIFVTHdqeealtmsDRI 204
Cdd:TIGR03719 157 advTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDA-------ESVAWLERHLqeypG-TVVAVTH---------DRY 219


                  ....
gi 545130686  205 FLMN 208
Cdd:TIGR03719 220 FLDN 223
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 6-234 2.54e-17

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 83.14  E-value: 2.54e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686     6 VQHLQKSYAGT--PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP-LSPQKRHIGMVFQ 82
Cdd:TIGR01257 1940 LNELTKVYSGTssPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTnISDVHQNMGYCPQ 2019

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    83 SYALFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:TIGR01257 2020 FDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTT 2099

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 545130686   163 ALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTApvdvFAAGFI 234
Cdd:TIGR01257 2100 GMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHLKSK----FGDGYI 2166
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
15-224 2.59e-17

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 80.31  E-value: 2.59e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  15 GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDiVPLSPQKRHIGMVFQSYAL---FPnMT 91
Cdd:PRK15056  19 GHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQP-TRQALQKNLVAYVPQSEEVdwsFP-VL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  92 VEQNVAFG----LRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALD-- 165
Cdd:PRK15056  97 VEDVVMMGryghMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDvk 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686 166 --ARIRKHLREqirqiQRELGLTTIFVTHDQEEALTMSDRIfLMNQGKIVQSGDAETLYTA 224
Cdd:PRK15056 177 teARIISLLRE-----LRDEGKTMLVSTHNLGSVTEFCDYT-VMVKGTVLASGPTETTFTA 231
PLN03232 PLN03232
ABC transporter C family member; Provisional
 17-222 3.26e-17

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 82.72  E-value: 3.26e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAG-LTSVDSGKILLDGQdiVPLSPQkrhIGMVFqsyalfpNMTVEQN 95
Cdd:PLN03232  631 PTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGeLSHAETSSVVIRGS--VAYVPQ---VSWIF-------NATVREN 698

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   96 VAFGLRMQKV---NADDShKRVQEVLQLVELKDLA--GRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDArirk 170
Cdd:PLN03232  699 ILFGSDFESErywRAIDV-TALQHDLDLLPGRDLTeiGERGVNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDA---- 773

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 545130686  171 HLREQIRQ--IQREL-GLTTIFVThDQEEALTMSDRIFLMNQGKIVQSGDAETLY 222
Cdd:PLN03232  774 HVAHQVFDscMKDELkGKTRVLVT-NQLHFLPLMDRIILVSEGMIKEEGTFAELS 827
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 16-195 4.60e-17

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 78.85  E-value: 4.60e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  16 TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIvplspqkrHIGmvfqsyalfPNMTVEQN 95
Cdd:COG2401   43 RYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPVAGCVDVPDN--------QFG---------REASLIDA 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  96 VAfglrmqkvnADDSHKRVQEVLQLVELKD--LAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLR 173
Cdd:COG2401  106 IG---------RKGDFKDAVELLNAVGLSDavLWLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVA 176

                        170       180
                 ....*....|....*....|..
gi 545130686 174 EQIRQIQRELGLTTIFVTHDQE 195
Cdd:COG2401  177 RNLQKLARRAGITLVVATHHYD 198
PLN03211 PLN03211
ABC transporter G-25; Provisional
 18-211 6.65e-17

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 81.46  E-value: 6.65e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  18 VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDS--GKILLDGQDivPLSPQKRHIGMVFQSYALFPNMTVEQN 95
Cdd:PLN03211  83 ILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANNRK--PTKQILKRTGFVTQDDILYPHLTVRET 160

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  96 VAFG--LRMQKVNADDSHKRVQEV------LQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDAR 167
Cdd:PLN03211 161 LVFCslLRLPKSLTKQEKILVAESviselgLTKCENTIIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDAT 240

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 545130686 168 IRKHLREQIRQIQRElGLTTIFVTHD-QEEALTMSDRIFLMNQGK 211
Cdd:PLN03211 241 AAYRLVLTLGSLAQK-GKTIVTSMHQpSSRVYQMFDSVLVLSEGR 284
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 56-229 8.79e-17

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 81.23  E-value: 8.79e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   56 DSGKILLDGQDIVP--LSPQKRHIGMVFQSYALFpNMTVEQNVAFGlrmqkvNADDSHKRVQEVLQLVELKDL------- 126
Cdd:PTZ00265 1275 NSGKILLDGVDICDynLKDLRNLFSIVSQEPMLF-NMSIYENIKFG------KEDATREDVKRACKFAAIDEFieslpnk 1347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  127 ----AGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHdQEEALTMSD 202
Cdd:PTZ00265 1348 ydtnVGPYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAH-RIASIKRSD 1426

                         170       180       190
                  ....*....|....*....|....*....|..
gi 545130686  203 RIFLMNQ----GKIVQS-GDAETLYTAPVDVF 229
Cdd:PTZ00265 1427 KIVVFNNpdrtGSFVQAhGTHEELLSVQDGVY 1458
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 22-212 1.47e-16

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 80.40  E-value: 1.47e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  22 INCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFPNMtveqnvafg 99
Cdd:PRK10522 342 INLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEdyRKLFSAVFTDFHLFDQL--------- 412

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 100 LRMQKVNADDshKRVQ---EVLQL---VELKDlaGRYPH-QMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHL 172
Cdd:PRK10522 413 LGPEGKPANP--ALVEkwlERLKMahkLELED--GRISNlKLSKGQKKRLALLLALAEERDILLLDEWAADQDPHFRREF 488

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 545130686 173 REQIRQIQRELGLTTIFVTHDqEEALTMSDRIFLMNQGKI 212
Cdd:PRK10522 489 YQVLLPLLQEMGKTIFAISHD-DHYFIHADRLLEMRNGQL 527
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 21-212 1.57e-16

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 79.87  E-value: 1.57e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGL-TSVDSGKILLDGQDIVPLSPQK--RH-IGMVFQS---YALFPNMTVE 93
Cdd:TIGR02633 278 DVSFSLRRGEILGVAGLVGAGRTELVQALFGAyPGKFEGNVFINGKPVDIRNPAQaiRAgIAMVPEDrkrHGIVPILGVG 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   94 QNV------AFGLRMQkVNADDSHKRVQEVLQLVELKDLAGRYP-HQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDA 166
Cdd:TIGR02633 358 KNItlsvlkSFCFKMR-IDAAAELQIIGSAIQRLKVKTASPFLPiGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDV 436

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 545130686  167 RIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKI 212
Cdd:TIGR02633 437 GAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLSDRVLVIGEGKL 481
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 25-204 2.31e-16

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 77.06  E-value: 2.31e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  25 EVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDiVPLSPQKrhIGMVFQsyalfpnMTVEQnvafgLRMQK 104
Cdd:cd03237   21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDT-VSYKPQY--IKADYE-------GTVRD-----LLSSI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 105 VNADDSHKRVQ-EVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQREL 183
Cdd:cd03237   86 TKDFYTHPYFKtEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFAENN 165

                        170       180
                 ....*....|....*....|.
gi 545130686 184 GLTTIFVTHDQEEALTMSDRI 204
Cdd:cd03237  166 EKTAFVVEHDIIMIDYLADRL 186
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 4-165 3.04e-16

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 79.21  E-value: 3.04e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDgqDIVplspqkrHIGMVFQS 83
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIG--ETV-------KLAYVDQS 393

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   84 Y-ALFPNMTVEQNVAFGLRMQKVN----------------ADDSHKRVQevlqlvelkdlagryphQMSGGQCQRVALAR 146
Cdd:TIGR03719 394 RdALDPNKTVWEEISGGLDIIKLGkreipsrayvgrfnfkGSDQQKKVG-----------------QLSGGERNRVHLAK 456

                         170
                  ....*....|....*....
gi 545130686  147 SLVTRPRLLLLDEPLSALD 165
Cdd:TIGR03719 457 TLKSGGNVLLLDEPTNDLD 475
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
101-223 3.48e-16

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 78.24  E-value: 3.48e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 101 RMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQ 180
Cdd:NF000106 112 R*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMV 191

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 545130686 181 RElGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYT 223
Cdd:NF000106 192 RD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKT 233
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 6-219 3.91e-16

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 76.60  E-value: 3.91e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTS--VDSGKILLDGQDIVPLSPQKR-HIG--MV 80
Cdd:CHL00131  10 IKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPAykILEGDILFKGESILDLEPEERaHLGifLA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSYALFPNMTVEQ--NVAFGLRMQKVNADDSH-----KRVQEVLQLVELKD-LAGRYPHQ-MSGGQCQRVALARSLVTR 151
Cdd:CHL00131  90 FQYPIEIPGVSNADflRLAYNSKRKFQGLPELDpleflEIINEKLKLVGMDPsFLSRNVNEgFSGGEKKRNEILQMALLD 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686 152 PRLLLLDEPLSALDARIRKHLREQIRQIqRELGLTTIFVTHDQEeaL---TMSDRIFLMNQGKIVQSGDAE 219
Cdd:CHL00131 170 SELAILDETDSGLDIDALKIIAEGINKL-MTSENSIILITHYQR--LldyIKPDYVHVMQNGKIIKTGDAE 237
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 12-197 5.09e-16

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 78.52  E-value: 5.09e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  12 SYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGltsvD-----SGKILLDGQ---------DIvplspqKRHI 77
Cdd:PRK10938 269 SYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG----DhpqgySNDLTLFGRrrgsgetiwDI------KKHI 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVfqSYALFPNMTVEQNV----------AFGLrMQKVnADDSHKRVQEVLQLVELKDLAGRYP-HQMSGGQcQRVAL-A 145
Cdd:PRK10938 339 GYV--SSSLHLDYRVSTSVrnvilsgffdSIGI-YQAV-SDRQQKLAQQWLDILGIDKRTADAPfHSLSWGQ-QRLALiV 413

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 545130686 146 RSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTHDQEEA 197
Cdd:PRK10938 414 RALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLLFVSHHAEDA 465
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
16-175 1.19e-15

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 74.50  E-value: 1.19e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  16 TPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDiVPLSPQKRHIGMVFQSYALFPNMTVEQN 95
Cdd:PRK13543  24 EPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKT-ATRGDRSRFMAYLGHLPGLKADLSTLEN 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  96 VAF-----GLRMQKVNADdshkrvqeVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDAR--- 167
Cdd:PRK13543 103 LHFlcglhGRRAKQMPGS--------ALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEgit 174

                        170
                 ....*....|...
gi 545130686 168 -----IRKHLREQ 175
Cdd:PRK13543 175 lvnrmISAHLRGG 187
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
15-213 1.43e-15

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 77.26  E-value: 1.43e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  15 GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK--RHiGMVF-----QSYALF 87
Cdd:PRK11288 265 GPGLREPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDaiRA-GIMLcpedrKAEGII 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  88 PNMTVEQNVAFGLRMQKVNADDSHKRVQEvlqlvelKDLAGRY----------PHQ----MSGGQCQRVALARSLVTRPR 153
Cdd:PRK11288 344 PVHSVADNINISARRHHLRAGCLINNRWE-------AENADRFirslniktpsREQlimnLSGGNQQKAILGRWLSEDMK 416

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545130686 154 LLLLDEPLSALDArirkHLREQIRQIQREL---GLTTIFVTHDQEEALTMSDRIFLMNQGKIV 213
Cdd:PRK11288 417 VILLDEPTRGIDV----GAKHEIYNVIYELaaqGVAVLFVSSDLPEVLGVADRIVVMREGRIA 475
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 15-210 1.46e-15

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 75.66  E-value: 1.46e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  15 GTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdiVPLSPQKRHIgmvfqsyalFPNmTVEQ 94
Cdd:cd03291   49 GAPVLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR--ISFSSQFSWI---------MPG-TIKE 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  95 NVAFGLRMQKVnaddshkRVQEVLQLVELKDLAGRYPHQ-----------MSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:cd03291  117 NIIFGVSYDEY-------RYKSVVKACQLEEDITKFPEKdntvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFGY 189

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 545130686 164 LDARIRKHLREQIrQIQRELGLTTIFVTHDQEEaLTMSDRIFLMNQG 210
Cdd:cd03291  190 LDVFTEKEIFESC-VCKLMANKTRILVTSKMEH-LKKADKILILHEG 234
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 11-221 1.72e-15

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 77.08  E-value: 1.72e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  11 KSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQK---RHIGMVFQSYALF 87
Cdd:PRK10982   6 KSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEaleNGISMVHQELNLV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  88 PNMTVEQNVAFGLRMQK---VNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSAL 164
Cdd:PRK10982  86 LQRSVMDNMWLGRYPTKgmfVDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSL 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 165 DARIRKHLREQIRQIqRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:PRK10982 166 TEKEVNHLFTIIRKL-KERGCGIVYISHKMEEIFQLCDEITILRDGQWIATQPLAGL 221
PTZ00243 PTZ00243
ABC transporter; Provisional
 21-219 2.80e-15

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 76.74  E-value: 2.80e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILldgqdivplspQKRHIGMVFQSyALFPNMTVEQNVAFgl 100
Cdd:PTZ00243  678 DVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVW-----------AERSIAYVPQQ-AWIMNATVRGNILF-- 743

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  101 rMQKVNADDSHKRVQeVLQL-VELKDLAGRYPHQ-------MSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHL 172
Cdd:PTZ00243  744 -FDEEDAARLADAVR-VSQLeADLAQLGGGLETEigekgvnLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVGERV 821

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 545130686  173 REQIRqIQRELGLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAE 219
Cdd:PTZ00243  822 VEECF-LGALAGKTRVLATH-QVHVVPRADYVVALGDGRVEFSGSSA 866
PLN03232 PLN03232
ABC transporter C family member; Provisional
 17-229 3.62e-15

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 76.55  E-value: 3.62e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP--LSPQKRHIGMVFQSYALFPNmTVEQ 94
Cdd:PLN03232 1250 PVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKfgLTDLRRVLSIIPQSPVLFSG-TVRF 1328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   95 NV-AFGlrmQKVNADdshkrVQEVLQLVELKDLAGRYP-----------HQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:PLN03232 1329 NIdPFS---EHNDAD-----LWEALERAHIKDVIDRNPfgldaevseggENFSVGQRQLLSLARALLRRSKILVLDEATA 1400

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686  163 ALDARIRKHLREQIRQiqrELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVF 229
Cdd:PLN03232 1401 SVDVRTDSLIQRTIRE---EFKSCTMLVIAHRLNTIIDCDKILVLSSGQVLEYDSPQELLSRDTSAF 1464
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
25-204 3.93e-15

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 76.00  E-value: 3.93e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  25 EVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDgqdiVPLS--PQKrhigmVFQSYalfpNMTVEQNvafgLRM 102
Cdd:PRK13409 361 EIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE----LKISykPQY-----IKPDY----DGTVEDL----LRS 423

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 103 QKVNADDSHKRVqEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRE 182
Cdd:PRK13409 424 ITDDLGSSYYKS-EIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEE 502

                        170       180
                 ....*....|....*....|....*.
gi 545130686 183 LGLTTIFVTHDqeeaLTM----SDRI 204
Cdd:PRK13409 503 REATALVVDHD----IYMidyiSDRL 524
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 4-217 4.65e-15

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 73.67  E-value: 4.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLT--SVDSGKILLDGQDIVPLSPQKRH---IG 78
Cdd:PRK09580   2 LSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLELSPEDRAgegIF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  79 MVFQ--------SYALFPNMTVeqNVAFGLRMQK-VNADDSHKRVQEVLQLVEL-KDLAGRYPHQ-MSGGQCQRVALARS 147
Cdd:PRK09580  82 MAFQypveipgvSNQFFLQTAL--NAVRSYRGQEpLDRFDFQDLMEEKIALLKMpEDLLTRSVNVgFSGGEKKRNDILQM 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686 148 LVTRPRLLLLDEPLSALDARIRKHLREQIRQIqRELGLTTIFVTHDQE-EALTMSDRIFLMNQGKIVQSGD 217
Cdd:PRK09580 160 AVLEPELCILDESDSGLDIDALKIVADGVNSL-RDGKRSFIIVTHYQRiLDYIKPDYVHVLYQGRIVKSGD 229
GguA NF040905
sugar ABC transporter ATP-binding protein;
11-220 5.06e-15

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 75.60  E-value: 5.06e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  11 KSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDS--GKILLDGQ-----DIVplSPQKRHIGMVFQS 83
Cdd:NF040905   9 KTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGSyeGEILFDGEvcrfkDIR--DSEALGIVIIHQE 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YALFPNMTVEQNVAFGLRMQK---VNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:NF040905  87 LALIPYLSIAENIFLGNERAKrgvIDWNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILDEP 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 161 LSALDARIRKHLREQIRQIqRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAET 220
Cdd:NF040905 167 TAALNEEDSAALLDLLLEL-KAQGITSIIISHKLNEIRRVADSITVLRDGRTIETLDCRA 225
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 21-212 5.32e-15

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 75.35  E-value: 5.32e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGL-TSVDSGKILLDGQDIVPLSPQ---KRHIGMVFQS---YALFPNMTVE 93
Cdd:PRK13549 280 DVSFSLRRGEILGIAGLVGAGRTELVQCLFGAyPGRWEGEIFIDGKPVKIRNPQqaiAQGIAMVPEDrkrDGIVPVMGVG 359

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  94 QNVAFGL--RMQKVNADDSHKRVQEVLQlvELKDLAGRYPH------QMSGGQCQRVALARSLVTRPRLLLLDEPLSALD 165
Cdd:PRK13549 360 KNITLAAldRFTGGSRIDDAAELKTILE--SIQRLKVKTASpelaiaRLSGGNQQKAVLAKCLLLNPKILILDEPTRGID 437

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 545130686 166 ARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKI 212
Cdd:PRK13549 438 VGAKYEIYKLINQLVQQ-GVAIIVISSELPEVLGLSDRVLVMHEGKL 483
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 12-210 5.51e-15

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 76.10  E-value: 5.51e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    12 SYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdiVPLSPQKRHIgmvfqsyalFPNmT 91
Cdd:TIGR01271  435 SLYVTPVLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR--ISFSPQTSWI---------MPG-T 502

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    92 VEQNVAFGLRMQKVnaddshkRVQEVLQLVELKDLAGRYPHQ-----------MSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:TIGR01271  503 IKDNIIFGLSYDEY-------RYTSVIKACQLEEDIALFPEKdktvlgeggitLSGGQRARISLARAVYKDADLYLLDSP 575

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 545130686   161 LSALDARIRKHLREqiRQIQRELGLTTIFVTHDQEEALTMSDRIFLMNQG 210
Cdd:TIGR01271  576 FTHLDVVTEKEIFE--SCLCKLMSNKTRILVTSKLEHLKKADKILLLHEG 623
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 21-210 8.18e-15

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 71.89  E-value: 8.18e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAG--LTSVDSGKILLDGQDIVPLSPqkRHIGMVFQSYALFPNMTVEqnvaf 98
Cdd:cd03232   25 NISGYVKPGTLTALMGESGAGKTTLLDVLAGrkTAGVITGEILINGRPLDKNFQ--RSTGYVEQQDVHSPNLTVR----- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  99 glrmqkvnaddshkrvqEVLQL-VELKDLagryphqmSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIR 177
Cdd:cd03232   98 -----------------EALRFsALLRGL--------SVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLK 152

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 545130686 178 QIQRElGLtTIFVTHDQEEALTMS--DRIFLMNQG 210
Cdd:cd03232  153 KLADS-GQ-AILCTIHQPSASIFEkfDRLLLLKRG 185
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 4-213 1.26e-14

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 74.54  E-value: 1.26e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDgqdivplspQKRHIGMVFQ- 82
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWS---------ENANIGYYAQd 390

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SYALFPN-MTV-------------EQNVAFGL-RMQkVNADDSHKRVQeVLqlvelkdlagryphqmSGGQCQRVALARS 147
Cdd:PRK15064 391 HAYDFENdLTLfdwmsqwrqegddEQAVRGTLgRLL-FSQDDIKKSVK-VL----------------SGGEKGRMLFGKL 452

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686 148 LVTRPRLLLLDEPLSALDArirkhlrEQIRQIQRELGL---TTIFVTHDQEEALTMSDRIFLMNQGKIV 213
Cdd:PRK15064 453 MMQKPNVLVMDEPTNHMDM-------ESIESLNMALEKyegTLIFVSHDREFVSSLATRIIEITPDGVV 514
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4-221 3.94e-14

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 73.24  E-value: 3.94e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVplspQKRHIGMVFQS 83
Cdd:NF033858   2 ARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMA----DARHRRAVCPR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YA---------LFPNMTVEQNVAFGLRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRL 154
Cdd:NF033858  78 IAympqglgknLYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 155 LLLDEPLSALDARIRKHLREQIRQIQREL-GLTTIFVTHDQEEALTMsDRIFLMNQGKIVQSGDAETL 221
Cdd:NF033858 158 LILDEPTTGVDPLSRRQFWELIDRIRAERpGMSVLVATAYMEEAERF-DWLVAMDAGRVLATGTPAEL 224
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 25-204 1.23e-13

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 71.35  E-value: 1.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  25 EVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKIllDGQDIVPLSPQKrhigmVFQSYalfpNMTVEQNvafgLRMQK 104
Cdd:COG1245  362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEV--DEDLKISYKPQY-----ISPDY----DGTVEEF----LRSAN 426

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 105 VNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELG 184
Cdd:COG1245  427 TDDFGSSYYKTEIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRG 506

                        170       180
                 ....*....|....*....|....
gi 545130686 185 LTTIFVTHDqeeaLTM----SDRI 204
Cdd:COG1245  507 KTAMVVDHD----IYLidyiSDRL 526
PLN03130 PLN03130
ABC transporter C family member; Provisional
 17-221 1.31e-13

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 71.69  E-value: 1.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGMVFQSYALFPNmTVEQ 94
Cdd:PLN03130 1253 PVLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDIskFGLMDLRKVLGIIPQAPVLFSG-TVRF 1331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   95 NV-AFGlrmQKVNADdshkrVQEVLQLVELKDLAGRYP-----------HQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:PLN03130 1332 NLdPFN---EHNDAD-----LWESLERAHLKDVIRRNSlgldaevseagENFSVGQRQLLSLARALLRRSKILVLDEATA 1403

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 545130686  163 ALDAR----IRKHLREQIRQIqrelglTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:PLN03130 1404 AVDVRtdalIQKTIREEFKSC------TMLIIAH-RLNTIIDCDRILVLDAGRVVEFDTPENL 1459
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 26-217 1.34e-13

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 71.68  E-value: 1.34e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    26 VAKGEFVTLLGPSGCGKSTLLRCIAGLTS---VDSGKILLDGQdivPL-SPQKRHIGMVFQSYALFPNMTVEQNVAFGLR 101
Cdd:TIGR00956  786 VKPGTLTALMGASGAGKTTLLNVLAERVTtgvITGGDRLVNGR---PLdSSFQRSIGYVQQQDLHLPTSTVRESLRFSAY 862

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   102 M---QKVNADDSHKRVQEVLQLVELKDLA----GRYPHQMSGGQCQRVALARSLVTRPRLLL-LDEPLSALDAR----IR 169
Cdd:TIGR00956  863 LrqpKSVSKSEKMEYVEEVIKLLEMESYAdavvGVPGEGLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQtawsIC 942

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 545130686   170 KHLREQIRQIQrelgltTIFVTHDQEEALTMS--DRIFLMNQG-KIVQSGD 217
Cdd:TIGR00956  943 KLMRKLADHGQ------AILCTIHQPSAILFEefDRLLLLQKGgQTVYFGD 987
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 4-214 1.36e-13

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 69.88  E-value: 1.36e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSY--AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDsGKILLDG--QDIVPLSPQKRHIGM 79
Cdd:cd03289    3 MTVKDLTAKYteGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTE-GDIQIDGvsWNSVPLQKWRKAFGV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  80 VFQSYALFPNmTVEQNVafglrmqKVNADDSHKRVQEVLQLVELKDLAGRYPHQM-----------SGGQCQRVALARSL 148
Cdd:cd03289   82 IPQKVFIFSG-TFRKNL-------DPYGKWSDEEIWKVAEEVGLKSVIEQFPGQLdfvlvdggcvlSHGHKQLMCLARSV 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 149 VTRPRLLLLDEPLSALDARIRKHLREQIRQiqrELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQ 214
Cdd:cd03289  154 LSKAKILLLDEPSAHLDPITYQVIRKTLKQ---AFADCTVILSEHRIEAMLECQRFLVIEENKVRQ 216
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 4-218 2.13e-13

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 71.09  E-value: 2.13e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686     4 VSVQHLQKSY--AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDsGKILLDG--QDIVPLSPQKRHIGM 79
Cdd:TIGR01271 1218 MDVQGLTAKYteAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTE-GEIQIDGvsWNSVTLQTWRKAFGV 1296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    80 VFQSYALFPNmTVEQNVafglrmqKVNADDSHKRVQEVLQLVELKDLAGRYPHQM-----------SGGQCQRVALARSL 148
Cdd:TIGR01271 1297 IPQKVFIFSG-TFRKNL-------DPYEQWSDEEIWKVAEEVGLKSVIEQFPDKLdfvlvdggyvlSNGHKQLMCLARSI 1368

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   149 VTRPRLLLLDEPLSALDARIRKHLREQIRQIQRElgLTTIFVTHDQEEALTMSDriFLMNQGKIVQSGDA 218
Cdd:TIGR01271 1369 LSKAKILLLDEPSAHLDPVTLQIIRKTLKQSFSN--CTVILSEHRVEALLECQQ--FLVIEGSSVKQYDS 1434
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 34-208 2.48e-13

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 70.53  E-value: 2.48e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  34 LLGPSGCGKSTLLRCIAGLTSVDSGKILLdgqdivplSPQKRhIGMVFQSYALFPNMTVEQNVAFGL--------RMQKV 105
Cdd:PRK11819  38 VLGLNGAGKSTLLRIMAGVDKEFEGEARP--------APGIK-VGYLPQEPQLDPEKTVRENVEEGVaevkaaldRFNEI 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 106 NA------DDSHK------RVQEVLQLVELKDL---------AGRYPH------QMSGGQCQRVALARSLVTRPRLLLLD 158
Cdd:PRK11819 109 YAayaepdADFDAlaaeqgELQEIIDAADAWDLdsqleiamdALRCPPwdakvtKLSGGERRRVALCRLLLEKPDMLLLD 188

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 545130686 159 EPLSALDAR----IRKHLreqirqiQRELGlTTIFVTHdqeealtmsDRIFLMN 208
Cdd:PRK11819 189 EPTNHLDAEsvawLEQFL-------HDYPG-TVVAVTH---------DRYFLDN 225
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 14-192 6.85e-13

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 69.39  E-value: 6.85e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   14 AGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGM-VFQSYALFPnMTV 92
Cdd:TIGR00954 463 NGDVLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKPAKGKLFYVPQRPYMTLgTLRDQIIYP-DSS 541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   93 EQnvafglrMQKvnADDSHKRVQEVLQLVELKDLAGR---------YPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:TIGR00954 542 ED-------MKR--RGLSDKDLEQILDNVQLTHILEReggwsavqdWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSA 612

                         170       180
                  ....*....|....*....|....*....
gi 545130686  164 ldarIRKHLREQIRQIQRELGLTTIFVTH 192
Cdd:TIGR00954 613 ----VSVDVEGYMYRLCREFGITLFSVSH 637
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 5-211 1.22e-12

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 68.11  E-value: 1.22e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIV---PLSPQKRHIGMVF 81
Cdd:PRK10762   6 QLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTfngPKSSQEAGIGIIH 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  82 QSYALFPNMTVEQNVAFGL----RMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:PRK10762  86 QELNLIPQLTIAENIFLGRefvnRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIM 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 545130686 158 DEPLSALDARIRKHLREQIRQIqRELGLTTIFVTHDQEEALTMSDRIFLMNQGK 211
Cdd:PRK10762 166 DEPTDALTDTETESLFRVIREL-KSQGRGIVYISHRLKEIFEICDDVTVFRDGQ 218
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 22-213 4.40e-12

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 66.75  E-value: 4.40e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  22 INCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQ--KRHIGMVFQSYALFPnmtveqnvafg 99
Cdd:COG4615  351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTADNREayRQLFSAVFSDFHLFD----------- 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 100 lRMQKVNADDSHKRVQEVLQLVELKDL----AGRY-PHQMSGGQCQRVALarsLVT----RPrLLLLDEPLSALDARIRK 170
Cdd:COG4615  420 -RLLGLDGEADPARARELLERLELDHKvsveDGRFsTTDLSQGQRKRLAL---LVAlledRP-ILVFDEWAADQDPEFRR 494

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 545130686 171 HLREQIRQIQRELGLTTIFVTHDqEEALTMSDRIFLMNQGKIV 213
Cdd:COG4615  495 VFYTELLPELKARGKTVIAISHD-DRYFDLADRVLKMDYGKLV 536
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 29-219 6.99e-12

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 66.67  E-value: 6.99e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    29 GEFVTLLGPSGCGKSTLLRCIAGLTS----VDSGKILLDGQDIVPLSPQKRhiGMVFQSYAL---FPNMTVEQNVAFGLR 101
Cdd:TIGR00956   87 GELTVVLGRPGSGCSTLLKTIASNTDgfhiGVEGVITYDGITPEEIKKHYR--GDVVYNAETdvhFPHLTVGETLDFAAR 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   102 MQKVNaddshKRVQEVLQLVELKDLAGRY------PHQ------------MSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:TIGR00956  165 CKTPQ-----NRPDGVSREEYAKHIADVYmatyglSHTrntkvgndfvrgVSGGERKRVSIAEASLGGAKIQCWDNATRG 239

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 545130686   164 LDA----RIRKHLREQIRQIQrelglTTIFVTHDQ--EEALTMSDRIFLMNQGKIVQSGDAE 219
Cdd:TIGR00956  240 LDSatalEFIRALKTSANILD-----TTPLVAIYQcsQDAYELFDKVIVLYEGYQIYFGPAD 296
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 18-225 7.55e-12

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 66.59  E-value: 7.55e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   18 VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILL-DGQDI--VPLSPQKRHIGMVFQSYALFPNmTVEQ 94
Cdd:PTZ00265  400 IYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIInDSHNLkdINLKWWRSKIGVVSQDPLLFSN-SIKN 478

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   95 NVAFGLRMQK--------------VNADDSHKR-------------------------------------VQEVLQLVEL 123
Cdd:PTZ00265  479 NIKYSLYSLKdlealsnyynedgnDSQENKNKRnscrakcagdlndmsnttdsneliemrknyqtikdseVVDVSKKVLI 558

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  124 KD-----------LAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELGLTTIFVTH 192
Cdd:PTZ00265  559 HDfvsalpdkyetLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIAH 638

                         250       260       270
                  ....*....|....*....|....*....|...
gi 545130686  193 dQEEALTMSDRIFLMNQGKIVQSGDAETLYTAP 225
Cdd:PTZ00265  639 -RLSTIRYANTIFVLSNRERGSTVDVDIIGEDP 670
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 17-231 1.07e-11

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 64.16  E-value: 1.07e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGMVFQSYALFPNmtveq 94
Cdd:cd03288   35 PVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDIskLPLHTLRSRLSIILQDPILFSG----- 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  95 NVAFGLRMQKVNADDshkRVQEVLQLVELKDLAGRYP-----------HQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:cd03288  110 SIRFNLDPECKCTDD---RLWEALEIAQLKNMVKSLPggldavvteggENFSVGQRQLFCLARAFVRKSSILIMDEATAS 186

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686 164 LDARIRKHLREQIRQIQRELGLTTIfvTHDQEEALTmSDRIFLMNQGKIVQSGDAETLYTAPVDVFAA 231
Cdd:cd03288  187 IDMATENILQKVVMTAFADRTVVTI--AHRVSTILD-ADLVLVLSRGILVECDTPENLLAQEDGVFAS 251
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 28-206 1.12e-11

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 62.01  E-value: 1.12e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    28 KGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLdgqdivplspqkrhigmvfqsyalfpnmtveqnvafglrmqkVNA 107
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY------------------------------------------IDG 38

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   108 DDSHKRVQEVLQLVelkdLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIR-----QIQRE 182
Cdd:smart00382  39 EDILEEVLDQLLLI----IVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrlllLLKSE 114

                          170       180
                   ....*....|....*....|....
gi 545130686   183 LGLTTIFVTHDQEEALTMSDRIFL 206
Cdd:smart00382 115 KNLTVILTTNDEKDLGPALLRRRF 138
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 6-195 1.36e-11

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 65.36  E-value: 1.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   6 VQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKIlldgqdivplspqkrHIGM-----V 80
Cdd:PRK11147 322 MENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRI---------------HCGTklevaY 386

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 FQSY--ALFPNMTVEQNVAFGLRMQKVNADDSHkrVQEVLQLVELKDLAGRYP-HQMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:PRK11147 387 FDQHraELDPEKTVMDNLAEGKQEVMVNGRPRH--VLGYLQDFLFHPKRAMTPvKALSGGERNRLLLARLFLKPSNLLIL 464

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 545130686 158 DEPLSALDARIRKHLREQIRQIQRelglTTIFVTHDQE 195
Cdd:PRK11147 465 DEPTNDLDVETLELLEELLDSYQG----TVLLVSHDRQ 498
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 18-231 1.70e-11

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 65.35  E-value: 1.70e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    18 VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDI--VPLSPQKRHIGMVFQSYALFPNmtveqn 95
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIakIGLHDLRFKITIIPQDPVLFSG------ 1374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686    96 vafGLRMqkvNADD----SHKRVQEVLQLVELKDLAGRYP----HQ-------MSGGQCQRVALARSLVTRPRLLLLDEP 160
Cdd:TIGR00957 1375 ---SLRM---NLDPfsqySDEEVWWALELAHLKTFVSALPdkldHEcaeggenLSVGQRQLVCLARALLRKTKILVLDEA 1448

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 545130686   161 LSALDARIRKHLREQIRQiQRElGLTTIFVTHDQEEALTMSdRIFLMNQGKIVQsgdaetlYTAPVDVFAA 231
Cdd:TIGR00957 1449 TAAVDLETDNLIQSTIRT-QFE-DCTVLTIAHRLNTIMDYT-RVIVLDKGEVAE-------FGAPSNLLQQ 1509
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 4-165 1.91e-11

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 64.75  E-value: 1.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLdGQDIvplspqkrHIGMVFQS 83
Cdd:PRK11819 325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETV--------KLAYVDQS 395

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 Y-ALFPNMTVEQNVAFGLRMQKVN----------------ADDSHKRVQevlqlvelkdlagryphQMSGGQCQRVALAR 146
Cdd:PRK11819 396 RdALDPNKTVWEEISGGLDIIKVGnreipsrayvgrfnfkGGDQQKKVG-----------------VLSGGERNRLHLAK 458

                        170
                 ....*....|....*....
gi 545130686 147 SLVTRPRLLLLDEPLSALD 165
Cdd:PRK11819 459 TLKQGGNVLLLDEPTNDLD 477
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 20-254 4.15e-11

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 63.76  E-value: 4.15e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  20 SDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKIlldgqDIvplspqKRHIGMVFQSYALFPNMTVEQNVAF- 98
Cdd:PRK13545  41 NNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTV-----DI------KGSAALIAISSGLNGQLTGIENIELk 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  99 GLRMQKvnaddSHKRVQEVL-QLVELKDLaGRYPHQ----MSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLR 173
Cdd:PRK13545 110 GLMMGL-----TKEKIKEIIpEIIEFADI-GKFIYQpvktYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCL 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 174 EQIRQIqRELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETLytapVDVFAAgFIGNYNLLDADKATQLLQRPI 253
Cdd:PRK13545 184 DKMNEF-KEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEV----VDHYDE-FLKKYNQMSVEERKDFREEQI 257


                 .
gi 545130686 254 S 254
Cdd:PRK13545 258 S 258
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 25-204 4.68e-11

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 60.66  E-value: 4.68e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  25 EVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVpLSPQKRhigmvfqsyalfpnmtveqnvafglrmqk 104
Cdd:cd03222   21 VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITPV-YKPQYI----------------------------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 105 vnaddshkrvqevlqlvelkdlagryphQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRELG 184
Cdd:cd03222   71 ----------------------------DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGK 122

                        170       180
                 ....*....|....*....|
gi 545130686 185 LTTIFVTHDQEEALTMSDRI 204
Cdd:cd03222  123 KTALVVEHDLAVLDYLSDRI 142
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 4-176 1.16e-10

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 59.89  E-value: 1.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFsDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLspQKRHIGMVFQS 83
Cdd:PRK13541   2 LSLHQLQFNIEQKNLF-DLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNI--AKPYCTYIGHN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 YALFPNMTVEQNVAFGLRMQkvnadDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:PRK13541  79 LGLKLEMTVFENLKFWSEIY-----NSAETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETN 153

                        170
                 ....*....|...
gi 545130686 164 LDARIRKHLREQI 176
Cdd:PRK13541 154 LSKENRDLLNNLI 166
PLN03140 PLN03140
ABC transporter G family member; Provisional
 29-216 1.95e-09

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 59.09  E-value: 1.95e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   29 GEFVTLLGPSGCGKSTLLRCIAGLTSvdSGKIllDGQDIVPLSPQK-----RHIGMVFQSYALFPNMTVEQNVAFG--LR 101
Cdd:PLN03140  906 GVLTALMGVSGAGKTTLMDVLAGRKT--GGYI--EGDIRISGFPKKqetfaRISGYCEQNDIHSPQVTVRESLIYSafLR 981

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  102 MQK-VNADDSHKRVQEVLQLVE---LKDLAGRYP--HQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQ 175
Cdd:PLN03140  982 LPKeVSKEEKMMFVDEVMELVEldnLKDAIVGLPgvTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRT 1061

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 545130686  176 IRQIQrELGLTTIFVTH----DQEEALtmsDRIFLMNQ-GKIVQSG 216
Cdd:PLN03140 1062 VRNTV-DTGRTVVCTIHqpsiDIFEAF---DELLLMKRgGQVIYSG 1103
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 29-193 2.51e-09

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 56.99  E-value: 2.51e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  29 GEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKI------------------------LLDGQDIVPLSPQkrhigmvfqsY 84
Cdd:cd03236   26 GQVLGLVGPNGIGKSTALKILAGKLKPNLGKFddppdwdeildefrgselqnyftkLLEGDVKVIVKPQ----------Y 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  85 A-LFPNmTVEQNVafGLRMQKVnaDDSHKrVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSA 163
Cdd:cd03236   96 VdLIPK-AVKGKV--GELLKKK--DERGK-LDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSY 169

                        170       180       190
                 ....*....|....*....|....*....|
gi 545130686 164 LDARIRKHLREQIRQIQRElGLTTIFVTHD 193
Cdd:cd03236  170 LDIKQRLNAARLIRELAED-DNYVLVVEHD 198
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
21-221 1.87e-08

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 54.44  E-value: 1.87e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQdivplspqkrhIGMVFQSYALFPNMTVEQNVAFGL 100
Cdd:PRK13546  42 DISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE-----------VSVIAISAGLSGQLTGIENIEFKM 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 101 RMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIq 180
Cdd:PRK13546 111 LCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEF- 189

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 545130686 181 RELGLTTIFVTHDQEEALTMSDRIFLMNQGKIVQSGDAETL 221
Cdd:PRK13546 190 KEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDV 230
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 21-216 1.20e-07

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 50.78  E-value: 1.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  21 DINCEVAKGEFVTLLGPSGCGKSTLLrciagltsvdsgkilldgQDIVPLSPQKRHIGmvfqSYALFPNmtveqnvafgl 100
Cdd:cd03238   13 NLDVSIPLNVLVVVTGVSGSGKSTLV------------------NEGLYASGKARLIS----FLPKFSR----------- 59

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 101 rmQKVNADDSHKRVQEV-LQLVELkdlaGRYPHQMSGGQCQRVALARSLVTRPR--LLLLDEPLSALDARIRKHLREQIR 177
Cdd:cd03238   60 --NKLIFIDQLQFLIDVgLGYLTL----GQKLSTLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQDINQLLEVIK 133

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 545130686 178 QIqRELGLTTIFVTHDqEEALTMSDRIFLM------NQGKIVQSG 216
Cdd:cd03238  134 GL-IDLGNTVILIEHN-LDVLSSADWIIDFgpgsgkSGGKVVFSG 176
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 32-205 1.69e-07

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 51.07  E-value: 1.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  32 VTLL-GPSGCGKSTLLRCIagltsvdsgKILLDGQdivpLSPQKRhigmvfqSYALFPNMTVEQNVAFGLRMQ-KVNADD 109
Cdd:cd03240   24 LTLIvGQNGAGKTTIIEAL---------KYALTGE----LPPNSK-------GGAHDPKLIREGEVRAQVKLAfENANGK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 110 SHKRVQEVLQLV--------ELKDLAGRYPHQMSGGQ------CQRVALARSLVTRPRLLLLDEPLSALDA-RIRKHLRE 174
Cdd:cd03240   84 KYTITRSLAILEnvifchqgESNWPLLDMRGRCSGGEkvlaslIIRLALAETFGSNCGILALDEPTTNLDEeNIEESLAE 163

                        170       180       190
                 ....*....|....*....|....*....|.
gi 545130686 175 QIRQIQRELGLTTIFVTHDqEEALTMSDRIF 205
Cdd:cd03240  164 IIEERKSQKNFQLIVITHD-EELVDAADHIY 193
PLN03073 PLN03073
ABC transporter F family; Provisional
 13-212 1.84e-07

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 52.55  E-value: 1.84e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  13 YAGTPV-FSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQSYALFPNMT 91
Cdd:PLN03073 518 YPGGPLlFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRSAKVRMAVFSQHHVDGLDLSSNPLLYMMR 597

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  92 VEQnvafGLRMQKVNADDSHKRVQEVLQLVELkdlagrypHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKH 171
Cdd:PLN03073 598 CFP----GVPEQKLRAHLGSFGVTGNLALQPM--------YTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDAVEA 665

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 545130686 172 LREQIRQIQRELglttIFVTHDQEEALTMSDRIFLMNQGKI 212
Cdd:PLN03073 666 LIQGLVLFQGGV----LMVSHDEHLISGSVDELWVVSEGKV 702
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 25-190 2.08e-07

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 52.32  E-value: 2.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  25 EVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLS--PQKRHIGMVFQSyaLFPNMTVEQNVAFGLRM 102
Cdd:PRK10938  25 TLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHITRLSfeQLQKLVSDEWQR--NNTDMLSPGEDDTGRTT 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 103 QKVNADDSHK--RVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQ 180
Cdd:PRK10938 103 AEIIQDEVKDpaRCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLASLH 182

                        170
                 ....*....|
gi 545130686 181 RElGLTTIFV 190
Cdd:PRK10938 183 QS-GITLVLV 191
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 17-223 2.93e-07

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 51.65  E-value: 2.93e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  17 PVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVPLSPQKRhIGMVF-------QSYALFPN 89
Cdd:PRK10982 262 PSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEA-INHGFalvteerRSTGIYAY 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  90 MTVEQNV----------AFGLRMQKVNADDShkrvQEVLQLVELKDlAGRYPH--QMSGGQCQRVALARSLVTRPRLLLL 157
Cdd:PRK10982 341 LDIGFNSlisnirnyknKVGLLDNSRMKSDT----QWVIDSMRVKT-PGHRTQigSLSGGNQQKVIIGRWLLTQPEILML 415

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545130686 158 DEPLSALDARIRKHLREQIRQIQRElGLTTIFVTHDQEEALTMSDRIFLMNQGKIvqSGDAETLYT 223
Cdd:PRK10982 416 DEPTRGIDVGAKFEIYQLIAELAKK-DKGIIIISSEMPELLGITDRILVMSNGLV--AGIVDTKTT 478
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 4-219 3.26e-07

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 51.71  E-value: 3.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   4 VSVQHLQKSYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGltsvdsgkilldgqdivPLSPQKRHIGMVfqs 83
Cdd:PRK10636 313 LKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAG-----------------ELAPVSGEIGLA--- 372

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  84 yalfpnmtveQNVAFGLRMQK----VNADDShkRVQEVLQLV------ELKDLAGRYPHQ----------MSGGQCQRVA 143
Cdd:PRK10636 373 ----------KGIKLGYFAQHqlefLRADES--PLQHLARLApqeleqKLRDYLGGFGFQgdkvteetrrFSGGEKARLV 440

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 144 LARSLVTRPRLLLLDEPLSALDARIRKHLREQIrqIQRELGLttIFVTHDQEEALTMSDRIFLMNQGKIVQ-SGDAE 219
Cdd:PRK10636 441 LALIVWQRPNLLLLDEPTNHLDLDMRQALTEAL--IDFEGAL--VVVSHDRHLLRSTTDDLYLVHDGKVEPfDGDLE 513
TOBE_2 pfam08402
TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the ...
 257-325 4.48e-07

TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the C-terminal strand of each domain is supplied by the partner. Probably involved in the recognition of small ligands such as molybdenum and sulphate. Found in ABC transporters immediately after the ATPase domain. In this family a strong RPE motif is found at the presumed N-terminus of the domain.


Pssm-ID: 462465 [Multi-domain]  Cd Length: 73  Bit Score: 46.84  E-value: 4.48e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  257 IAIRPEAIELSRTGE-LDALVRSHSLLGNVIRYRIEARGVELVVDVLNRSADDLHPDGQRLALSIDPSAL 325
Cdd:pfam08402   1 LAIRPEKIRLAAAANgLSGTVTDVEYLGDHTRYHVELAGGEELVVRVPNAHARPPAPGDRVGLGWDPEDA 70
GguA NF040905
sugar ABC transporter ATP-binding protein;
5-213 5.58e-07

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 50.94  E-value: 5.58e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   5 SVQHLQksYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLT--SVDSGKILLDGQDIVpLSPQKRHI--GMV 80
Cdd:NF040905 264 TVYHPL--HPERKVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGRSygRNISGTVFKDGKEVD-VSTVSDAIdaGLA 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  81 F-----QSYALFPNMTVEQNVAFGlRMQKVnaddSHKRVqeVLQLVELKdLAGRYPHQM--------------SGGQCQR 141
Cdd:NF040905 341 YvtedrKGYGLNLIDDIKRNITLA-NLGKV----SRRGV--IDENEEIK-VAEEYRKKMniktpsvfqkvgnlSGGNQQK 412

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 545130686 142 VALARSLVTRPRLLLLDEPLSALD--ARIrkhlreQIRQIQREL---GLTTIFVTHDQEEALTMSDRIFLMNQGKIV 213
Cdd:NF040905 413 VVLSKWLFTDPDVLILDEPTRGIDvgAKY------EIYTIINELaaeGKGVIVISSELPELLGMCDRIYVMNEGRIT 483
PLN03073 PLN03073
ABC transporter F family; Provisional
 12-220 4.24e-06

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 48.32  E-value: 4.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  12 SYAGTPVFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAgLTSVD----SGKIL-----LDGQDIVPL-----SPQKRHI 77
Cdd:PLN03073 186 SVGGRDLIVDASVTLAFGRHYGLVGRNGTGKTTFLRYMA-MHAIDgipkNCQILhveqeVVGDDTTALqcvlnTDIERTQ 264

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  78 GMVFQSYALFPNMTVEQNVAFGLRMQKVNADDSH----KRVQEVLQLVELKD-----------LAG---------RYPHQ 133
Cdd:PLN03073 265 LLEEEAQLVAQQRELEFETETGKGKGANKDGVDKdavsQRLEEIYKRLELIDaytaearaasiLAGlsftpemqvKATKT 344

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 134 MSGGQCQRVALARSLVTRPRLLLLDEPLSALDARIRKHLREQIRQIQRelglTTIFVTHDQEEALT-MSDRIFLMNQGKI 212
Cdd:PLN03073 345 FSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYLLKWPK----TFIVVSHAREFLNTvVTDILHLHGQKLV 420


                 ....*...
gi 545130686 213 VQSGDAET 220
Cdd:PLN03073 421 TYKGDYDT 428
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 28-193 5.71e-06

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 47.86  E-value: 5.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  28 KGEFVTLLGPSGCGKSTLLRCIAG-----LTSVDSGkilLDGQDIVplspqKRHIGMVFQSYalFpNMTVEQNVAFGLRM 102
Cdd:COG1245   98 KGKVTGILGPNGIGKSTALKILSGelkpnLGDYDEE---PSWDEVL-----KRFRGTELQDY--F-KKLANGEIKVAHKP 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 103 QKV----------------NADDsHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLSALDA 166
Cdd:COG1245  167 QYVdlipkvfkgtvrelleKVDE-RGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDI 245

                        170       180
                 ....*....|....*....|....*..
gi 545130686 167 RIRKHLREQIRQIQRElGLTTIFVTHD 193
Cdd:COG1245  246 YQRLNVARLIRELAEE-GKYVLVVEHD 271
PTZ00243 PTZ00243
ABC transporter; Provisional
 15-229 1.41e-05

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 46.70  E-value: 1.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   15 GTP-VFSDINCEVAKGEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLDGQDIVP--LSPQKRHIGMVFQSYALFpNMT 91
Cdd:PTZ00243 1321 GLPlVLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAygLRELRRQFSMIPQDPVLF-DGT 1399

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   92 VEQNVAFGLRMQKvnaddshkrvQEVLQLVELKDLAGRYPHQMSG--------------GQCQRVALARSLVTRPR-LLL 156
Cdd:PTZ00243 1400 VRQNVDPFLEASS----------AEVWAALELVGLRERVASESEGidsrvleggsnysvGQRQLMCMARALLKKGSgFIL 1469

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 545130686  157 LDEPLSALDARIRkhlreqiRQIQREL-----GLTTIFVTHdQEEALTMSDRIFLMNQGKIVQSGDAETLYTAPVDVF 229
Cdd:PTZ00243 1470 MDEATANIDPALD-------RQIQATVmsafsAYTVITIAH-RLHTVAQYDKIIVMDHGAVAEMGSPRELVMNRQSIF 1539
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 27-205 3.31e-05

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 43.50  E-value: 3.31e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  27 AKGEFVTLLGPSGCGKSTLLRCIAgltsvdsgkilldgqdivplspqkrhigmvfqsyalfpnmtveqnVAFGLRMQKVN 106
Cdd:cd03227   19 GEGSLTIITGPNGSGKSTILDAIG---------------------------------------------LALGGAQSATR 53

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 107 A-DDSHKRVQEVLQLVELKDLAgrypHQMSGGQCQRVALA-----RSLVTRPrLLLLDEPLSALDARIRKHLREQIRQiQ 180
Cdd:cd03227   54 RrSGVKAGCIVAAVSAELIFTR----LQLSGGEKELSALAlilalASLKPRP-LYILDEIDRGLDPRDGQALAEAILE-H 127

                        170       180
                 ....*....|....*....|....*
gi 545130686 181 RELGLTTIFVTHDQEEALtMSDRIF 205
Cdd:cd03227  128 LVKGAQVIVITHLPELAE-LADKLI 151
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
28-193 5.59e-05

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 44.80  E-value: 5.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  28 KGEFVTLLGPSGCGKSTLLRCIAG-----LTSVDSG-------------------KILLDGQDIVPLSPQKRH-IGMVFQ 82
Cdd:PRK13409  98 EGKVTGILGPNGIGKTTAVKILSGelipnLGDYEEEpswdevlkrfrgtelqnyfKKLYNGEIKVVHKPQYVDlIPKVFK 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  83 SyalfpnmTVEQNVAfglrmqKVnadDSHKRVQEVLQLVELKDLAGRYPHQMSGGQCQRVALARSLVTRPRLLLLDEPLS 162
Cdd:PRK13409 178 G-------KVRELLK------KV---DERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTS 241

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 545130686 163 ALDarirkhLREQIR--QIQREL--GLTTIFVTHD 193
Cdd:PRK13409 242 YLD------IRQRLNvaRLIRELaeGKYVLVVEHD 270
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 110-268 9.44e-05

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 44.43  E-value: 9.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  110 SHKRVQEVLQ-----LVELKDLAGRY--PHQ----MSGGQCQRVALARSL------VTrprlLLLDEPLSALDARIRKHL 172
Cdd:PRK00635  442 KSLSIEEVLQglksrLSILIDLGLPYltPERalatLSGGEQERTALAKHLgaeligIT----YILDEPSIGLHPQDTHKL 517

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  173 REQIRQIqRELGLTTIFVTHDqEEALTMSDRIFLMNQGKIVQSGdaETLYT-APVDvfaagFIGNYNLLDADKATQLLQR 251
Cdd:PRK00635  518 INVIKKL-RDQGNTVLLVEHD-EQMISLADRIIDIGPGAGIFGG--EVLFNgSPRE-----FLAKSDSLTAKYLRQELTI 588

                         170
                  ....*....|....*..
gi 545130686  252 PISSRIAIRPEAIELSR 268
Cdd:PRK00635  589 PIPEKRTNSLGTLTLSK 605
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 134-216 3.59e-04

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 41.09  E-value: 3.59e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 134 MSGGQCQRVALARSLVTRPR--LLLLDEPLSALDARIRKHLREQIRQIqRELGLTTIFVTHDqEEALTMSDRIFLM---- 207
Cdd:cd03270  138 LSGGEAQRIRLATQIGSGLTgvLYVLDEPSIGLHPRDNDRLIETLKRL-RDLGNTVLVVEHD-EDTIRAADHVIDIgpga 215

                         90
                 ....*....|.
gi 545130686 208 --NQGKIVQSG 216
Cdd:cd03270  216 gvHGGEIVAQG 226
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 29-251 8.72e-04

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 40.92  E-value: 8.72e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  29 GEFVTLLGPSGCGKSTLLRCIAGLTSVDSGKILLdgqdivplsPQKRHIGMVFQSYALFPNMTVEQNV-------AFGLR 101
Cdd:PRK10636  27 GQKVGLVGKNGCGKSTLLALLKNEISADGGSYTF---------PGNWQLAWVNQETPALPQPALEYVIdgdreyrQLEAQ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 102 MQKVNA-DDSHKRVQ-----EVLQLVELKDLAGRYPHQM--------------SGGQCQRVALARSLVTRPRLLLLDEPL 161
Cdd:PRK10636  98 LHDANErNDGHAIATihgklDAIDAWTIRSRAASLLHGLgfsneqlerpvsdfSGGWRMRLNLAQALICRSDLLLLDEPT 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686 162 SALDARIRKHLREQIRQIQRelglTTIFVTHDQEEALTMSDRIFLMNQGKIVQsgdaetlYTapvdvfaagfiGNYNLLD 241
Cdd:PRK10636 178 NHLDLDAVIWLEKWLKSYQG----TLILISHDRDFLDPIVDKIIHIEQQSLFE-------YT-----------GNYSSFE 235

                        250
                 ....*....|
gi 545130686 242 ADKATQLLQR 251
Cdd:PRK10636 236 VQRATRLAQQ 245
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 70-204 2.14e-03

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 40.00  E-value: 2.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   70 LSPQKRHIGMVFQSYALFPNMTVEQNVAFglrMQKVNADDSHKRV-QEVLQ-----LVELKDLA------GRYPHQMSGG 137
Cdd:TIGR00630 416 LKPEALAVTVGGKSIADVSELSIREAHEF---FNQLTLTPEEKKIaEEVLKeirerLGFLIDVGldylslSRAAGTLSGG 492

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 545130686  138 QCQRVALARSLVTRPR--LLLLDEPLSALDARIRKHLREQIRQIqRELGLTTIFVTHDqEEALTMSDRI 204
Cdd:TIGR00630 493 EAQRIRLATQIGSGLTgvLYVLDEPSIGLHQRDNRRLINTLKRL-RDLGNTLIVVEHD-EDTIRAADYV 559
AAA_23 pfam13476
AAA domain;
19-189 2.62e-03

AAA domain;


Pssm-ID: 463890 [Multi-domain]  Cd Length: 190  Bit Score: 38.25  E-value: 2.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   19 FSDINCEVAKGefVTLL-GPSGCGKSTLLRCIA--------GLTSVDSGKILLDGQDIVPLSPQKRHIGMVFQSYALFPN 89
Cdd:pfam13476   9 FRDQTIDFSKG--LTLItGPNGSGKTTILDAIKlalygktsRLKRKSGGGFVKGDIRIGLEGKGKAYVEITFENNDGRYT 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   90 MTVEqnvafglRMQKVNADDSHKRVQEVLQLVELKDLAGRYPHQmsggqcqrvaLARSLVTRPRLLLLDEplSALDARIR 169
Cdd:pfam13476  87 YAIE-------RSRELSKKKGKTKKKEILEILEIDELQQFISEL----------LKSDKIILPLLVFLGQ--EREEEFER 147

                         170       180
                  ....*....|....*....|
gi 545130686  170 KHLREQIRQIQRELGLTTIF 189
Cdd:pfam13476 148 KEKKERLEELEKALEEKEDE 167
AAA_25 pfam13481
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
 26-192 7.69e-03

AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.


Pssm-ID: 463892 [Multi-domain]  Cd Length: 193  Bit Score: 36.98  E-value: 7.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686   26 VAKGEFVTLLGPSGCGKSTLLRCIAglTSVDSGKILLDGQDIVplspqkRHIGMVFQSyalfpnmTVEQNVAFGLRMQKV 105
Cdd:pfam13481  30 LPAGGLGLLAGAPGTGKTTLALDLA--AAVATGKPWLGGPRVP------EQGKVLYVS-------AEGPADELRRRLRAA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545130686  106 NADDSHKRVQEVLQLVELKDLagryPHQMSGGQC---QRVALARSL--VTRPRLLLLDePLSAL------DARIRKHLRE 174
Cdd:pfam13481  95 GADLDLPARLLFLSLVESLPL----FFLDRGGPLldaDVDALEAALeeVEDPDLVVID-PLARAlggdenSNSDVGRLVK 169

                         170
                  ....*....|....*...
gi 545130686  175 QIRQIQRELGLTTIFVTH 192
Cdd:pfam13481 170 ALDRLARRTGATVLLVHH 187
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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