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Conserved domains on  [gi|545613213|ref|WP_021737598|]
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ABC transporter permease [Eubacterium ramulus]

Protein Classification

ABC transporter permease( domain architecture ID 10003065)

ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of substrates including gylcine betaine, choline, and carnitine

Gene Ontology:  GO:0140359|GO:0042626|GO:0055085|GO:0016020
PubMed:  25750732|24638992|31571164|27273632|26517919|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 6-207 1.24e-59

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 186.03  E-value: 1.24e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   6 EYFQTHGQEYVHMIWQHLYLSLLAVGIAAAVGIPCGILSLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGVKPAL 85
Cdd:COG1174    7 EWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPAPAI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  86 AALVILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAGGLG 165
Cdd:COG1174   87 IALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGAGGLG 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 545613213 166 ILIFNGINLLKTEYLVIGGGTVAVITMLCSMALGAVEKKISR 207
Cdd:COG1174  167 DLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTP 208
 
Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 6-207 1.24e-59

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 186.03  E-value: 1.24e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   6 EYFQTHGQEYVHMIWQHLYLSLLAVGIAAAVGIPCGILSLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGVKPAL 85
Cdd:COG1174    7 EWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPAPAI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  86 AALVILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAGGLG 165
Cdd:COG1174   87 IALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGAGGLG 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 545613213 166 ILIFNGINLLKTEYLVIGGGTVAVITMLCSMALGAVEKKISR 207
Cdd:COG1174  167 DLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTP 208
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
23-184 1.13e-16

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 77.05  E-value: 1.13e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  23 LYLSLLAVGIAAAVGIPCGILSLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGVKPALAALVILAIPPILIQTTL 102
Cdd:PRK10952 150 LALVLTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTIL 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213 103 AFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAGGLGILIFNGINLLKTEYLVI 182
Cdd:PRK10952 230 GINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATV 309


                 ..
gi 545613213 183 GG 184
Cdd:PRK10952 310 GG 311
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 19-198 2.97e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 62.68  E-value: 2.97e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  19 IWQHLYLSLLAVGIAAAVGIPCGILSLR-APRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGVK---------PALAAL 88
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARkRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGwgilpglglPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  89 VILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAGGLGILI 168
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170       180       190
                 ....*....|....*....|....*....|
gi 545613213 169 FNGINLLKTEYLVIGGGTVAVITMLCSMAL 198
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 37-209 4.93e-11

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 59.23  E-value: 4.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   37 GIPCGILS--LRAPRIKKILTTGFSVLRIIPSLAVLVILIPIM-----GVGVKPALAALVILAIPPILIQTTLAFSQVPD 109
Cdd:pfam00528   1 GIPLGIIAalRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAilsilGHGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  110 FLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAG-GLGILIFNGINLLKTEYLVIGGGTVA 188
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDYPEIQGPVLAAA 160

                         170       180
                  ....*....|....*....|.
gi 545613213  189 VITMLCSMALGAVEKKISRAL 209
Cdd:pfam00528 161 LILLLLNLLVDILQRLLDPRV 181
modB_ABC TIGR02141
molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, ...
 20-145 6.90e-06

molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, of the molybdate ABC transporter. This system has been characterized in E. coli, Staphylococcus carnosus, Rhodobacter capsulatus and Azotobacter vinlandii. Molybdate is chemically similar to sulfate, thiosulfate, and selenate. These related substrates, and sometimes molybdate itself, can be transported by the homologous sulfate receptor. Some apparent molybdenum transport operons include a permease related to this ModB, although less similar than some sulfate permease proteins and not included in this model. [Transport and binding proteins, Anions]


Pssm-ID: 273993 [Multi-domain]  Cd Length: 208  Bit Score: 44.93  E-value: 6.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   20 WQHLYLSLLAVGIAAAVGIPCG-ILSLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMGVG-----------------V 81
Cdd:TIGR02141   1 WLSLKVAVIATLLLLPLGIPVAwLLARSRFRGKPLLEVLVTLPLVLPPTVLGFYLLIAFGPNgpigkllelfgislvftF 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545613213   82 KPALAALVILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMA 145
Cdd:TIGR02141  81 TGAVLASVIVSFPLMVQPIRAAFEAVDPDLEEAARTLGASESQTFLKVTLPLAFPGLLAGAVLS 144
 
Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 6-207 1.24e-59

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 186.03  E-value: 1.24e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   6 EYFQTHGQEYVHMIWQHLYLSLLAVGIAAAVGIPCGILSLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGVKPAL 85
Cdd:COG1174    7 EWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPAPAI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  86 AALVILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAGGLG 165
Cdd:COG1174   87 IALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGAGGLG 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 545613213 166 ILIFNGINLLKTEYLVIGGGTVAVITMLCSMALGAVEKKISR 207
Cdd:COG1174  167 DLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTP 208
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 19-207 1.12e-26

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 102.53  E-value: 1.12e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  19 IWQHLYLSLLAV----GIAAAVGIPCGILSLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGVKPALAALVILAIP 94
Cdd:COG0600   59 LWEHLLASLLRVllgfALAALLGVPLGLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFF 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  95 PILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAG-GLGILIFNGIN 173
Cdd:COG0600  139 PILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASsGLGYLILDARQ 218

                        170       180       190
                 ....*....|....*....|....*....|....
gi 545613213 174 LLKTEYLVIGGGTVAVITMLCSMALGAVEKKISR 207
Cdd:COG0600  219 LLDTDLVFAAILVIGLLGLLLDLLLRLLERRLLR 252
ProW COG4176
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 23-188 1.08e-23

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443335  Cd Length: 275  Bit Score: 94.78  E-value: 1.08e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  23 LYLSLLAVGIAAAVGIPCGILSLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGVKPALAALVILAIPPILIQTTL 102
Cdd:COG4176   96 LALVLVAVLIALLIGIPLGILAARSDRVSRIVRPVLDFMQTMPAFVYLIPAVMLFGIGKVPGVIATVIFALPPAIRLTNL 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213 103 AFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISG----IRMAMSEVIasatLAAYIGAGGLGILIFNGINllkte 178
Cdd:COG4176  176 GIRQVPKELVEAADAFGATPWQLLFKVQLPLALPTIMAGvnqtIMLALSMVV----IASMIGAGGLGQEVLRALQ----- 246

                        170
                 ....*....|
gi 545613213 179 YLVIGGGTVA 188
Cdd:COG4176  247 RLDIGLGFEA 256
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
23-184 1.13e-16

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 77.05  E-value: 1.13e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  23 LYLSLLAVGIAAAVGIPCGILSLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGVKPALAALVILAIPPILIQTTL 102
Cdd:PRK10952 150 LALVLTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTIL 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213 103 AFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAGGLGILIFNGINLLKTEYLVI 182
Cdd:PRK10952 230 GINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATV 309


                 ..
gi 545613213 183 GG 184
Cdd:PRK10952 310 GG 311
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 4-165 6.02e-14

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 67.77  E-value: 6.02e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   4 YVEYFQTHGQEYVHMIWQHLYLSLLAVGIAAAVGIPCGIL--------SLRAPRIKKILTTGFSVLRIIPSLAVLVILIP 75
Cdd:COG2011    1 MLTMWSELWPLLLQATGETLYMVGVSTLIAVLLGLPLGVLlvltrpggLLPNPVLYRVLGVIVNIFRSIPFIILLVALIP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  76 ----IMG--VGVKPALAALVILAIPPI--LIQTtlAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMS 147
Cdd:COG2011   81 ltrlIVGtsIGTTAAIVPLTIAAIPFFarLVEN--ALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLI 158

                        170
                 ....*....|....*...
gi 545613213 148 EVIASATLAAYIGAGGLG 165
Cdd:COG2011  159 SLIGYSAMAGAVGGGGLG 176
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 19-198 2.97e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 62.68  E-value: 2.97e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  19 IWQHLYLSLLAVGIAAAVGIPCGILSLR-APRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGVK---------PALAAL 88
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARkRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGwgilpglglPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  89 VILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAGGLGILI 168
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170       180       190
                 ....*....|....*....|....*....|
gi 545613213 169 FNGINLLKTEYLVIGGGTVAVITMLCSMAL 198
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
19-203 1.11e-11

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 62.26  E-value: 1.11e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  19 IWQHLYLS----LLAVGIAAAVGIPCGILSLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGVKPALAALVILAIP 94
Cdd:PRK11365  58 LWQHLAISswraLIGFSIGGSLGLILGLISGLSRWGERLLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLF 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  95 PILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGA-GGLGILIFNGIN 173
Cdd:PRK11365 138 PIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISAnSGIGYLAMNARE 217

                        170       180       190
                 ....*....|....*....|....*....|
gi 545613213 174 LLKTEYLVIGGGTVAVITMLCSMALGAVEK 203
Cdd:PRK11365 218 FLQTDVVVVAIILYALLGKLADVSAQLLER 247
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 37-209 4.93e-11

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 59.23  E-value: 4.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   37 GIPCGILS--LRAPRIKKILTTGFSVLRIIPSLAVLVILIPIM-----GVGVKPALAALVILAIPPILIQTTLAFSQVPD 109
Cdd:pfam00528   1 GIPLGIIAalRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAilsilGHGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  110 FLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAG-GLGILIFNGINLLKTEYLVIGGGTVA 188
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDYPEIQGPVLAAA 160

                         170       180
                  ....*....|....*....|.
gi 545613213  189 VITMLCSMALGAVEKKISRAL 209
Cdd:pfam00528 161 LILLLLNLLVDILQRLLDPRV 181
PRK10160 PRK10160
taurine ABC transporter permease TauC;
19-206 1.38e-09

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 56.33  E-value: 1.38e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  19 IWQHLYLSL----LAVGIAAAVGIPCGILSLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGVKPALAALVILAIP 94
Cdd:PRK10160  76 LWQHLAASLtrivLALLAAVVIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFA 155

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  95 PILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAM----SEVIASATLAAyigAGGLGILIFN 170
Cdd:PRK10160 156 PVAMSALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLgvgwSTLVAAELIAA---TRGLGFMVQS 232

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 545613213 171 GINLLKTEYLVIGGGTVAVITMLCSMALGAVEKKIS 206
Cdd:PRK10160 233 AGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLT 268
PstC COG0573
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 18-147 2.00e-08

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440338 [Multi-domain]  Cd Length: 303  Bit Score: 53.17  E-value: 2.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  18 MIWQHLYLSLLAVGIAAAVGIPCGI-LSLRAP-RIKKILTTGFSVLRIIPS----LAVLVILIPIMGVGVKP------AL 85
Cdd:COG0573   78 LIVGTLLVSLIALLIAVPLGLGIAIfLSEYAPpRLRRILKPAIELLAGIPSvvygFWGLFVLVPLLRDLFPWppsgfsLL 157

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545613213  86 AALVILAIPPILIQTTL---AFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMS 147
Cdd:COG0573  158 TAGIVLAIMILPTITSLsrdALRAVPRSLREAALALGATRWETIRKVVLPAARSGIIAAVILGLG 222
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
19-165 2.55e-08

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 52.04  E-value: 2.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  19 IWQHLYLSLLAVGIAAAVGIPCGIL--------SLRAPRIKKILTTGFSVLRIIPSLAVLVILIP----IMG--VGVKPA 84
Cdd:PRK10782  13 VWETLAMTFVSGFFGFVIGLPVGVLlyvtrpgqIIANAKLYRTLSALVNIFRSIPFIILLVWMIPftrvIVGtsIGLQAA 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  85 LAALVILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAGGL 164
Cdd:PRK10782  93 IVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMGGAVGAGGL 172


                 .
gi 545613213 165 G 165
Cdd:PRK10782 173 G 173
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 4-174 6.01e-06

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 45.49  E-value: 6.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   4 YVEYFQThgQEYVHMIWQHLYLSLLAVGIAAAVGIPCGI-LSLRAPRIKKILTTGFSVLRIIP------SLAVLVILIPI 76
Cdd:COG1177   50 YAELFSD--PRLLDALLNSLLIALLSTLLATVLGTPAALaLARYRFRGRRLLLALLLLPLVVPgivlgvALLLLFSALGL 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  77 MGvGVKPALAALVILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLA 156
Cdd:COG1177  128 SG-GLWGLILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVIT 206

                        170       180
                 ....*....|....*....|.
gi 545613213 157 AYIGAGG---LGILIFNGINL 174
Cdd:COG1177  207 LFLAGPGvttLPVYIYSMIRR 227
modB_ABC TIGR02141
molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, ...
 20-145 6.90e-06

molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, of the molybdate ABC transporter. This system has been characterized in E. coli, Staphylococcus carnosus, Rhodobacter capsulatus and Azotobacter vinlandii. Molybdate is chemically similar to sulfate, thiosulfate, and selenate. These related substrates, and sometimes molybdate itself, can be transported by the homologous sulfate receptor. Some apparent molybdenum transport operons include a permease related to this ModB, although less similar than some sulfate permease proteins and not included in this model. [Transport and binding proteins, Anions]


Pssm-ID: 273993 [Multi-domain]  Cd Length: 208  Bit Score: 44.93  E-value: 6.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   20 WQHLYLSLLAVGIAAAVGIPCG-ILSLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMGVG-----------------V 81
Cdd:TIGR02141   1 WLSLKVAVIATLLLLPLGIPVAwLLARSRFRGKPLLEVLVTLPLVLPPTVLGFYLLIAFGPNgpigkllelfgislvftF 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 545613213   82 KPALAALVILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMA 145
Cdd:TIGR02141  81 TGAVLASVIVSFPLMVQPIRAAFEAVDPDLEEAARTLGASESQTFLKVTLPLAFPGLLAGAVLS 144
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
19-207 7.97e-06

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 45.54  E-value: 7.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  19 IWQHLYLSLLAVGIAAAVGIPCGILSLRAP-RIKKILTTGFSVLRIIPS----LAVLVILIPIMGVGVKPALAALVI--- 90
Cdd:COG1178  340 LLNSLLLALLAALLAVLLALLLAYLVRRRRgRLARLLDRLAMLPYAVPGivlgLGLLLLFNRPLPLLLYGTLAILVLayv 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  91 -LAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAGG---LGI 166
Cdd:COG1178  420 vRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPGfetLAV 499

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 545613213 167 LIFngiNLLKTEYLVIGGGTVAVITMLCSMALGAVEKKISR 207
Cdd:COG1178  500 LIY---QLASSGRYGEAAALALLLVLVSLLPVLLLERLLGR 537
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
15-162 1.21e-05

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 45.15  E-value: 1.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  15 YVHMIWQHLYLSLLAVGIAAAVGIPCG-ILSLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMG------------VGV 81
Cdd:COG1178   52 LWRALGNTLLLALLVTLLSLLLGVPLAwLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGpngllntllralFGL 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  82 KP--------ALAALVILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASA 153
Cdd:COG1178  132 EPpdiyglggIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADF 211


                 ....*....
gi 545613213 154 TLAAYIGAG 162
Cdd:COG1178  212 GTPLVLGGG 220
3a0107s02c TIGR00974
phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of ...
 17-151 2.56e-05

phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of permease proteins in the ABC (high affinity) phosphate transporter. In a number of species, this permease is fused with the PtsC protein (TIGR02138). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273373  Cd Length: 271  Bit Score: 43.76  E-value: 2.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   17 HMIWQHLYLSLLAVGIAAAVGIPCGILSL---RAPRIKKILTTGFSVLRIIPS-------LAVLVILIPIMGVGVKPALA 86
Cdd:TIGR00974  54 PAIVGTLLLTLLAIVIAVPLGIGAAIYLAeyaNGSRFTKIIRFAVDILAGVPSivvglfgYGFFVLTYLGGGFSLLAGAL 133

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 545613213   87 ALVILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIA 151
Cdd:TIGR00974 134 ALALLILPVIIRTTEEALKAVPKDLREASLALGATKWQTIFKVVLPAALPGILTGIILSIARAAG 198
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 18-170 3.36e-05

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 43.41  E-value: 3.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   18 MIWQHLYLSLLAVGIAAAVGIPCGI-LSLRAP-RIKKILTTGFSVLRIIPS----------------------LAVLVIL 73
Cdd:TIGR02138  64 LIVGTLITSLIALLIAVPVGIGIAIfLSEIAPkRVRSVLKPVVELLAGIPSvvygfwglfvlvpflkphfqpfLGSNLGL 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   74 IPIMGVGVKPALAALVILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASA 153
Cdd:TIGR02138 144 IPLFGGPILTAGIVLAIMILPTIASISRDALRAVPRSYKEASYALGATKWETIRRVILPAARSGIVGAVVLGLGRALGET 223

                         170
                  ....*....|....*..
gi 545613213  154 TLAAYIGAGGLGILIFN 170
Cdd:TIGR02138 224 MAVTMVIGNVFPISPLS 240
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 84-159 7.28e-05

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 41.96  E-value: 7.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  84 ALAALVILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRM----AMSEVIASATLAAYI 159
Cdd:COG4149   93 AVLASVVVSLPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAGAVLafarALGEFGATLMFAGNI 172
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 10-174 9.94e-05

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 41.76  E-value: 9.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   10 THGQEYVHMIWQHLYLSLLAVGIAAAVGIPCGILSLR----APRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGVKPAL 85
Cdd:TIGR01097  51 SYLPRILKALLETLAMAILGTVLAAVLAVPLALLAARnitpSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGV 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213   86 AALVILAIPPILIQTTLAFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAGGLG 165
Cdd:TIGR01097 131 LALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLSYTLYRFEINVRAAAVLGLVGAGGIG 210


                  ....*....
gi 545613213  166 ILIFNGINL 174
Cdd:TIGR01097 211 LELDTAIGL 219
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 13-175 4.77e-04

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 39.68  E-value: 4.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  13 QEYVHMIWQHLYLSLLAVGIAAAVGIPCGILSLR----APRIKKILTTGFSVLRIIPSLAVLVILIPIMGVGvkpALAAL 88
Cdd:COG3639   47 PDLLSALLETLAIALLGTLLGAVLALPLAFLAARnlapNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLG---PFAGV 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  89 VILAIPPILIQTTL---AFSQVPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEVIASATLAAYIGAGGLG 165
Cdd:COG3639  124 LALAIHTIGFLGKLfaeAIEEIDPGPVEALRATGASRLQVIRYGVLPQVLPQFLSYTLYRFEINIRAATVLGLVGAGGIG 203

                        170
                 ....*....|
gi 545613213 166 ILIFNGINLL 175
Cdd:COG3639  204 LLLNEAIRLF 213
pstA PRK11268
phosphate ABC transporter permease PstA;
26-154 4.39e-03

phosphate ABC transporter permease PstA;


Pssm-ID: 183065 [Multi-domain]  Cd Length: 295  Bit Score: 37.36  E-value: 4.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 545613213  26 SLLAVGIAAAVGIPCGIL-----------SLRAPRIKKILTTGFSVLRIIPSLAVLVILIPIMG-----VGVKpALAALV 89
Cdd:PRK11268  86 SGLLILWATVVGTPLGIMagiylaeygrkSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEhfsgwAGVI-ALALLQ 164

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 545613213  90 IlaipPILIQTTLAFSQ-VPDFLLEVADAMGMDKKRKFRQVEVPLAMPGIISGIRMAMSEvIASAT 154
Cdd:PRK11268 165 I----PIVIRTTENMLKlVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGVLLAIAR-IAGET 225
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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