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Conserved domains on  [gi|549799341|ref|WP_022562770|]
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MULTISPECIES: ABC transporter ATP-binding protein [Agrobacterium]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467929)

ABC transporter ATP-binding protein similar to the ATPase subunits (GsiA and OppF) of complexes which are responsible for coupling the energy of ATP hydrolysis to the import of glutathione or oligopeptides

CATH:  3.40.50.300
Gene Ontology:  GO:0042626|GO:0140359|GO:0016887|GO:0005524
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 16-572 0e+00

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 813.15  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIEGKVMLGGRDLLALPE 95
Cdd:COG4172    4 MPLLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDPAAHPSGSILFDGQDLLGLSE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSGGMRQ 175
Cdd:COG4172   84 RELRRIRGNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRLDAYPHQLSGGQRQ 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDD 255
Cdd:COG4172  164 RVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAE 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 256 IFHRGRHPYTRALLSAVPKlgsmkerllparfpiidiktGESQPVADvkdtvsgGRTPILSVKDLTTRFDIRSGLFGRKS 335
Cdd:COG4172  244 LFAAPQHPYTRKLLAAEPR--------------------GDPRPVPP-------DAPPLLEARDLKVWFPIKRGLFRRTV 296

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIePTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQDPFASL 415
Cdd:COG4172  297 GHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQDLDGLSRRALRPLRRRMQVVFQDPFGSL 375

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAIMEPFIEHRLG-TKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:COG4172  376 SPRMTVGQIIAEGLRVHGPGlSAAERRARVAEALEEVGLDPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSA 455

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 495 LDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAVPVPD 572
Cdd:COG4172  456 LDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHPYTRALLAAAPLLE 533
 
Name Accession Description Interval E-value
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 16-572 0e+00

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 813.15  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIEGKVMLGGRDLLALPE 95
Cdd:COG4172    4 MPLLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDPAAHPSGSILFDGQDLLGLSE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSGGMRQ 175
Cdd:COG4172   84 RELRRIRGNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRLDAYPHQLSGGQRQ 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDD 255
Cdd:COG4172  164 RVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAE 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 256 IFHRGRHPYTRALLSAVPKlgsmkerllparfpiidiktGESQPVADvkdtvsgGRTPILSVKDLTTRFDIRSGLFGRKS 335
Cdd:COG4172  244 LFAAPQHPYTRKLLAAEPR--------------------GDPRPVPP-------DAPPLLEARDLKVWFPIKRGLFRRTV 296

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIePTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQDPFASL 415
Cdd:COG4172  297 GHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQDLDGLSRRALRPLRRRMQVVFQDPFGSL 375

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAIMEPFIEHRLG-TKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:COG4172  376 SPRMTVGQIIAEGLRVHGPGlSAAERRARVAEALEEVGLDPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSA 455

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 495 LDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAVPVPD 572
Cdd:COG4172  456 LDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHPYTRALLAAAPLLE 533
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 18-612 0e+00

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 727.03  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIEGKVMLGGR------DLL 91
Cdd:PRK10261  12 VLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRRrsrqviELS 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  92 ALPEEEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSG 171
Cdd:PRK10261  92 EQSAAQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQTILSRYPHQLSG 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 172 GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:PRK10261 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETG 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 252 TTDDIFHRGRHPYTRALLSAVPKLGSMKERLLPARFPIIDIKTGESQPVADVKDTVSGGRtPILSVKDLTTRFDIRSGLF 331
Cdd:PRK10261 252 SVEQIFHAPQHPYTRALLAAVPQLGAMKGLDYPRRFPLISLEHPAKQEPPIEQDTVVDGE-PILQVRNLVTRFPLRSGLL 330

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 332 GRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQDP 411
Cdd:PRK10261 331 NRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRDIQFIFQDP 410

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 412 FASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEA 491
Cdd:PRK10261 411 YASLDPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEA 490

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 492 VSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAVPVP 571
Cdd:PRK10261 491 VSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLMAAVPVA 570

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|.
gi 549799341 572 DPARRQIKRNMATDEIRSPIRPVDYVPPQRLYREVSAGHLV 612
Cdd:PRK10261 571 DPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYV 611
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 18-251 3.62e-112

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 334.86  E-value: 3.62e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdKKTSrieGKVMLGGRDLLALPEEe 97
Cdd:cd03257    1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLL-KPTS---GSIIFDGKDLLKLSRR- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 MRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIrLLEKVRIPNAKNRFDDYPHQFSGGMRQRV 177
Cdd:cd03257   76 LRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAV-LLLLVGVGLPEEVLNRYPHELSGGQRQRV 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:cd03257  155 AIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
 38-271 6.77e-78

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 246.51  E-value: 6.77e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   38 VRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIEGKVMLGGRDLLALpeeemrKVRGKDISMIFQEPMTSL 117
Cdd:TIGR02770   2 VQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLTQTSGEILLDGRPLLPL------SIRGRHIATIMQNPRTAF 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  118 NPIFPIGKQIAEALTVHQDISSSAaKAEVIRLLEKVRIPNAKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTT 197
Cdd:TIGR02770  76 NPLFTMGNHAIETLRSLGKLSKQA-RALILEALEAVGLPDPEEVLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTT 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341  198 ALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRGRHPYTRALLSA 271
Cdd:TIGR02770 155 DLDVVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLSA 228
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 344-491 1.79e-38

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 138.93  E-value: 1.79e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEvlkLDKTTLRTMRRSVQMIFQDPFasLDPRMSVGT 423
Cdd:pfam00005   4 VSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQD---LTDDERKSLRKEIGYVFQDPQ--LFPRLTVRE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341  424 AIMEPFIEHRLgTKQQAREKAADLLEKVGLSPDM---MRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEA 491
Cdd:pfam00005  79 NLRLGLLLKGL-SKREKDARAEEALEKLGLGDLAdrpVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEP 148
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
170-402 3.99e-19

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 91.72  E-value: 3.99e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEE-EGMSVLFITHDMGVvAEVSDRTIVMFRGDVV 248
Cdd:NF033858 138 SGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAErPGMSVLVATAYMEE-AERFDWLVAMDAGRVL 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 249 ETGTTDDIFHRgrhpyTRAllsavPKLGSMKERLLPARfpiidiKTGESQPVADVKDTVSGGRTPILSVKDLTTRFdirs 328
Cdd:NF033858 217 ATGTPAELLAR-----TGA-----DTLEAAFIALLPEE------KRRGHQPVVIPPRPADDDDEPAIEARGLTMRF---- 276

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 329 glfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlklDKTTLRTMRR 402
Cdd:NF033858 277 -------GDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPV---DAGDIATRRR 340
GguA NF040905
sugar ABC transporter ATP-binding protein;
18-500 8.00e-17

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 83.69  E-value: 8.00e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFrvdGGWKSVvRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLdkktSRI------EGKVMLGGRdll 91
Cdd:NF040905   1 ILEMRGITKTF---PGVKAL-DDVNLSVREGEIHALCGENGAGKS----TLMKVL----SGVyphgsyEGEILFDGE--- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  92 alpEEEMRKVRG---KDISMIFQE----PMTSL--NpIFpIGKQIAEaltvHQDISSSAAKAEVIRLLEKVRIpnaknrf 162
Cdd:NF040905  66 ---VCRFKDIRDseaLGIVIIHQElaliPYLSIaeN-IF-LGNERAK----RGVIDWNETNRRARELLAKVGL------- 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 163 DDYPHQFSG----GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDR 238
Cdd:NF040905 130 DESPDTLVTdigvGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELK-AQGITSIIISHKLNEIRRVADS 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 239 TIVMFRGDVVET------GTTDDIFHRGrhpytrallsavpklgsMKERLLPARFPIIDIKTGEsqpvadvkdtvsggrt 312
Cdd:NF040905 209 ITVLRDGRTIETldcradEVTEDRIIRG-----------------MVGRDLEDRYPERTPKIGE---------------- 255

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFDIRSglfGRKsgavhAVEKVSFDLAEGETLSLVGESGCGK-----STTGRSITRLIeptSGDVMLDGY 387
Cdd:NF040905 256 VVFEVKNWTVYHPLHP---ERK-----VVDDVSLNVRRGEIVGIAGLMGAGRtelamSVFGRSYGRNI---SGTVFKDGK 324

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 388 EVlkldktTLRTMRRSVQ--------------MIFQDP------FASLdPRMSVGTAIMEpFIEHRLGT--KQQAREKAA 445
Cdd:NF040905 325 EV------DVSTVSDAIDaglayvtedrkgygLNLIDDikrnitLANL-GKVSRRGVIDE-NEEIKVAEeyRKKMNIKTP 396

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 446 DLLEKVGlspdmmrrfphEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIK 500
Cdd:NF040905 397 SVFQKVG-----------NLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAK 440
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
37-240 5.23e-16

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 76.50  E-value: 5.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  37 VVRNMSFEIAPRETVAIVGESGSGKSVtslsimrLLdkktsriegKVMLGgrdLLALPEEEMRKVRGKDISMIFQEpmTS 116
Cdd:NF040873   7 VLHGVDLTIPAGSLTAVVGPNGSGKST-------LL---------KVLAG---VLRPTSGTVRRAGGARVAYVPQR--SE 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 117 LNPIFPigkqiaeaLTVHQDIS-------------SSAAKAEVIRLLEKVRIPN-AKNRFDDyphqFSGGMRQRVMIAMA 182
Cdd:NF040873  66 VPDSLP--------LTVRDLVAmgrwarrglwrrlTRDDRAAVDDALERVGLADlAGRQLGE----LSGGQRQRALLAQG 133

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 183 LASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTI 240
Cdd:NF040873 134 LAQEADLLLLDEPTTGLDAESRERIIALLAEEH-ARGATVVVVTHDLELVRRADPCVL 190
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
136-256 6.18e-12

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 67.45  E-value: 6.18e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 136 DISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQ 215
Cdd:NF000106 115 DLSRKDARARADELLERFSLTEAAGR---AAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMV 191

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 549799341 216 eEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:NF000106 192 -RDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
336-535 2.87e-11

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 63.02  E-value: 2.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVL-------KLDKTTLRTMRRSVQMif 408
Cdd:NF040873   3 GGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVayvpqrsEVPDSLPLTVRDLVAM-- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 409 qdpfaSLDPRMSvgtaimePFIEHRlgtkQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVA 488
Cdd:NF040873  81 -----GRWARRG-------LWRRLT----RDDRAAVDDALERVGLA-DLAGRQLGELSGGQRQRALLAQGLAQEADLLLL 143

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 549799341 489 DEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRV 535
Cdd:NF040873 144 DEPTTGLDAESRERI-IALLAEEHARGATVVVVTHDLELVRRADPCV 189
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 47-246 2.88e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 53.15  E-value: 2.88e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    47 PRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIegkVMLGGRDLLALPEEEMRKVrgkdismifqepmtslnpifpigkq 126
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGV---IYIDGEDILEEVLDQLLLI------------------------- 52

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   127 iaealtvhqdisssaakaevirllekvripnaknRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQ 206
Cdd:smart00382  53 ----------------------------------IVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEAL 98

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 549799341   207 ILDLIKT-----LQEEEGMSVLFITHDMGVVAE-----VSDRTIVMFRGD 246
Cdd:smart00382  99 LLLLEELrllllLKSEKNLTVILTTNDEKDLGPallrrRFDRRIVLLLIL 148
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
304-547 6.32e-07

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 51.66  E-value: 6.32e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 304 KDTVSGGRTPILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTtGRSITRLIEPTSGDVM 383
Cdd:NF000106   3 RKTISNGARNAVEVRGLVKHF-----------GEVKAVDGVDLDVREGTVLGVLGP*GAA**R-GALPAHV*GPDAGRRP 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 384 LDGYEVLKLDKTTLRTM--RRSVQMIFQDPFASLDPRMSVGTAIMEpfiehrlgTKQQAREKAADLLEKVGLSpDMMRRF 461
Cdd:NF000106  71 WRF*TWCANRRALRRTIg*HRPVR*GRRESFSGRENLYMIGR*LDL--------SRKDARARADELLERFSLT-EAAGRA 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 462 PHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHdMAVVERVSHRVAVMYLG 541
Cdd:NF000106 142 AAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQY-MEEAEQLAHELTVIDRG 220


                 ....*.
gi 549799341 542 EIVEIG 547
Cdd:NF000106 221 RVIADG 226
GguA NF040905
sugar ABC transporter ATP-binding protein;
170-248 2.45e-06

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 50.56  E-value: 2.45e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:NF040905 406 SGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELA-AEGKGVIVISSELPELLGMCDRIYVMNEGRIT 483
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
131-256 1.62e-05

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 48.20  E-value: 1.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 131 LTVHQ---------DISSSAAKAEVIRLLEkvripnaknRFD--DYPHQFSG----GMRQRVMIAMALASKPKLLIADEP 195
Cdd:NF033858 354 LTVRQnlelharlfHLPAAEIAARVAEMLE---------RFDlaDVADALPDslplGIRQRLSLAVAVIHKPELLILDEP 424

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341 196 TTALDVTIQGQILDLIKTLQEEEGMSVlFI-THDMGvVAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:NF033858 425 TSGVDPVARDMFWRLLIELSREDGVTI-FIsTHFMN-EAERCDRISLMHAGRVLASDTPAAL 484
 
Name Accession Description Interval E-value
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 16-572 0e+00

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 813.15  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIEGKVMLGGRDLLALPE 95
Cdd:COG4172    4 MPLLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDPAAHPSGSILFDGQDLLGLSE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSGGMRQ 175
Cdd:COG4172   84 RELRRIRGNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRLDAYPHQLSGGQRQ 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDD 255
Cdd:COG4172  164 RVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAE 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 256 IFHRGRHPYTRALLSAVPKlgsmkerllparfpiidiktGESQPVADvkdtvsgGRTPILSVKDLTTRFDIRSGLFGRKS 335
Cdd:COG4172  244 LFAAPQHPYTRKLLAAEPR--------------------GDPRPVPP-------DAPPLLEARDLKVWFPIKRGLFRRTV 296

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIePTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQDPFASL 415
Cdd:COG4172  297 GHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQDLDGLSRRALRPLRRRMQVVFQDPFGSL 375

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAIMEPFIEHRLG-TKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:COG4172  376 SPRMTVGQIIAEGLRVHGPGlSAAERRARVAEALEEVGLDPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSA 455

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 495 LDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAVPVPD 572
Cdd:COG4172  456 LDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHPYTRALLAAAPLLE 533
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 18-612 0e+00

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 727.03  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIEGKVMLGGR------DLL 91
Cdd:PRK10261  12 VLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRRrsrqviELS 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  92 ALPEEEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSG 171
Cdd:PRK10261  92 EQSAAQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQTILSRYPHQLSG 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 172 GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:PRK10261 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETG 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 252 TTDDIFHRGRHPYTRALLSAVPKLGSMKERLLPARFPIIDIKTGESQPVADVKDTVSGGRtPILSVKDLTTRFDIRSGLF 331
Cdd:PRK10261 252 SVEQIFHAPQHPYTRALLAAVPQLGAMKGLDYPRRFPLISLEHPAKQEPPIEQDTVVDGE-PILQVRNLVTRFPLRSGLL 330

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 332 GRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQDP 411
Cdd:PRK10261 331 NRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRDIQFIFQDP 410

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 412 FASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEA 491
Cdd:PRK10261 411 YASLDPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEA 490

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 492 VSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAVPVP 571
Cdd:PRK10261 491 VSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLMAAVPVA 570

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|.
gi 549799341 572 DPARRQIKRNMATDEIRSPIRPVDYVPPQRLYREVSAGHLV 612
Cdd:PRK10261 571 DPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYV 611
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 16-574 0e+00

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 690.10  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFRvdGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKkTSRIEGKVMLGGRDLLALPE 95
Cdd:COG1123    2 TPLLEVRDLSVRYP--GGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPH-GGRISGEVLLDGRDLLELSE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 eemrKVRGKDISMIFQEPMTSLNPIfPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNaknRFDDYPHQFSGGMRQ 175
Cdd:COG1123   79 ----ALRGRRIGMVFQDPMTQLNPV-TVGDQIAEALEN-LGLSRAEARARVLELLEAVGLER---RLDRYPHQLSGGQRQ 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDD 255
Cdd:COG1123  150 RVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEE 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 256 IFHRGRhpytraLLSAVPKLGSMKERllparfpiidiktgesqpvadvKDTVSGGRTPILSVKDLTTRFDIRsglfgrKS 335
Cdd:COG1123  230 ILAAPQ------ALAAVPRLGAARGR----------------------AAPAAAAAEPLLEVRNLSKRYPVR------GK 275

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQDPFASL 415
Cdd:COG1123  276 GGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLRELRRRVQMVFQDPYSSL 355

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSAL 495
Cdd:COG1123  356 NPRMTVGDIIAEPLRLHGLLSRAERRERVAELLERVGLPPDLADRYPHELSGGQRQRVAIARALALEPKLLILDEPTSAL 435

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 496 DVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAVPVPDPA 574
Cdd:COG1123  436 DVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANPQHPYTRALLAAVPSLDPA 514
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 14-566 0e+00

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 530.43  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  14 SVSPVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLL-DKKTSRIEGKVMLGGRDLLA 92
Cdd:PRK15134   1 MTQPLLAIENLSVAFRQQQTVRTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLLpSPPVVYPSGDIRFHGESLLH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  93 LPEEEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSGG 172
Cdd:PRK15134  81 ASEQTLRGVRGNKIAMIFQEPMVSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 173 MRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGT 252
Cdd:PRK15134 161 ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNR 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 253 TDDIFHRGRHPYTRALLSAVPklgsmkerllparfpiidikTGESQPVADvkdtvsgGRTPILSVKDLTTRFDIRSGLFG 332
Cdd:PRK15134 241 AATLFSAPTHPYTQKLLNSEP--------------------SGDPVPLPE-------PASPLLDVEQLQVAFPIRKGILK 293

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 333 RKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIePTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQDPF 412
Cdd:PRK15134 294 RTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLI-NSQGEIWFDGQPLHNLNRRQLLPVRHRIQVVFQDPN 372

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 413 ASLDPRMSVGTAIMEPF-IEHRLGTKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEA 491
Cdd:PRK15134 373 SSLNPRLNVLQIIEEGLrVHQPTLSAAQREQQVIAVMEEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEP 452

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 492 VSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMS 566
Cdd:PRK15134 453 TSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEYTRQLLA 527
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 308-612 6.33e-161

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 463.43  E-value: 6.33e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 308 SGGRTPILSVKDLTTRFDIRSGLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGY 387
Cdd:COG4608    1 AAMAEPLLEVRDLKKHFPVRGGLFGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 388 EVLKLDKTTLRTMRRSVQMIFQDPFASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRFPHEFSG 467
Cdd:COG4608   81 DITGLSGRELRPLRRRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHADRYPHEFSG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 468 GQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:COG4608  161 GQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 548 PRAAVFDNPQHPYTKKLMSAVPVPDPARRQiKRNMATDEIRSPIRP-----------------VDYVPPqrlYREVSAGH 610
Cdd:COG4608  241 PRDELYARPLHPYTQALLSAVPVPDPERRR-ERIVLEGDVPSPLNPpsgcrfhtrcpyaqdrcATEEPP---LREVGPGH 316


                 ..
gi 549799341 611 LV 612
Cdd:COG4608  317 QV 318
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 18-284 3.12e-157

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 453.74  E-value: 3.12e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKkTSRIEGKVMLGGRDLLALPEEE 97
Cdd:COG0444    1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPP-PGITSGEILFDGEDLLKLSEKE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 MRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSGGMRQRV 177
Cdd:COG0444   80 LRKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDPERRLDRYPHELSGGMRQRV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIF 257
Cdd:COG0444  160 MIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELF 239

                        250       260
                 ....*....|....*....|....*..
gi 549799341 258 HRGRHPYTRALLSAVPKLGSMKERLLP 284
Cdd:COG0444  240 ENPRHPYTRALLSSIPRLDPDGRRLIP 266
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 314-579 1.16e-130

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 385.95  E-value: 1.16e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFDIRSGlfgrksgAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEP---TSGDVMLDGYEVL 390
Cdd:COG0444    1 LLEVRNLKVYFPTRRG-------VVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 391 KLDKTTLRTMR-RSVQMIFQDPFASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSP--DMMRRFPHEFSG 467
Cdd:COG0444   74 KLSEKELRKIRgREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDpeRRLDRYPHELSG 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 468 GQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:COG0444  154 GMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEG 233

                        250       260       270
                 ....*....|....*....|....*....|..
gi 549799341 548 PRAAVFDNPQHPYTKKLMSAVPVPDPARRQIK 579
Cdd:COG0444  234 PVEELFENPRHPYTRALLSSIPRLDPDGRRLI 265
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 312-593 1.45e-112

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 340.02  E-value: 1.45e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFDIRSGLFgRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITrLIE-PTSGDVMLDGYEVL 390
Cdd:PRK11308   3 QPLLQAIDLKKHYPVKRGLF-KPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLT-MIEtPTGGELYYQGQDLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 391 KLDKTTLRTMRRSVQMIFQDPFASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQR 470
Cdd:PRK11308  81 KADPEAQKLLRQKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLRPEHYDRYPHMFSGGQR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 471 QRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRA 550
Cdd:PRK11308 161 QRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKE 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 549799341 551 AVFDNPQHPYTKKLMSAVPV--PDPARRQIKrnmATDEIRSPIRP 593
Cdd:PRK11308 241 QIFNNPRHPYTQALLSATPRlnPDDRRERIK---LTGELPSPLNP 282
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 18-251 3.62e-112

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 334.86  E-value: 3.62e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdKKTSrieGKVMLGGRDLLALPEEe 97
Cdd:cd03257    1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLL-KPTS---GSIIFDGKDLLKLSRR- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 MRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIrLLEKVRIPNAKNRFDDYPHQFSGGMRQRV 177
Cdd:cd03257   76 LRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAV-LLLLVGVGLPEEVLNRYPHELSGGQRQRV 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:cd03257  155 AIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 311-593 3.70e-111

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 336.29  E-value: 3.70e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 311 RTPILSVKDLTTRFDIRSG--LFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYE 388
Cdd:PRK15079   5 KKVLLEVADLKVHFDIKDGkqWFWQPPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 389 VLKLDKTTLRTMRRSVQMIFQDPFASLDPRMSVGTAIMEPF-IEHRLGTKQQAREKAADLLEKVGLSPDMMRRFPHEFSG 467
Cdd:PRK15079  85 LLGMKDDEWRAVRSDIQMIFQDPLASLNPRMTIGEIIAEPLrTYHPKLSRQEVKDRVKAMMLKVGLLPNLINRYPHEFSG 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 468 GQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:PRK15079 165 GQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELG 244

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 549799341 548 PRAAVFDNPQHPYTKKLMSAVPVPDParrQIKRN----MATDEIRSPIRP 593
Cdd:PRK15079 245 TYDEVYHNPLHPYTKALMSAVPIPDP---DLERNktiqLLEGELPSPINP 291
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 6-283 8.47e-107

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 325.14  E-value: 8.47e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   6 TSMEQTGGSvSPVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdKKTSRIEGKVML 85
Cdd:PRK09473   1 TVPLAQQQA-DALLDVKDLRVTFSTPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLL-AANGRIGGSATF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  86 GGRDLLALPEEEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDY 165
Cdd:PRK09473  79 NGREILNLPEKELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEARKRMKMY 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 166 PHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:PRK09473 159 PHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAG 238

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 549799341 246 DVVETGTTDDIFHRGRHPYTRALLSAVPKLGSMKERLL 283
Cdd:PRK09473 239 RTMEYGNARDVFYQPSHPYSIGLLNAVPRLDAEGESLL 276
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 314-547 3.56e-103

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 311.75  E-value: 3.56e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFdirsglfGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLD 393
Cdd:cd03257    1 LLEVKNLSVSF-------PTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 KTTLRTMRRSVQMIFQDPFASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAA-DLLEKVGLSPDMMRRFPHEFSGGQRQR 472
Cdd:cd03257   74 RRLRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAVlLLLVGVGLPEEVLNRYPHELSGGQRQR 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 473 IAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:cd03257  154 VAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 18-288 4.17e-101

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 310.52  E-value: 4.17e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDkktsrIEGKVM-----LGGRDLLA 92
Cdd:PRK11022   3 LLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLID-----YPGRVMaekleFNGQDLQR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  93 LPEEEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSGG 172
Cdd:PRK11022  78 ISEKERRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGG 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 173 MRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGT 252
Cdd:PRK11022 158 MSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGK 237

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 549799341 253 TDDIFHRGRHPYTRALLSAVPKLGSMKERL--LPARFP 288
Cdd:PRK11022 238 AHDIFRAPRHPYTQALLRALPEFAQDKARLasLPGVVP 275
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 17-273 1.89e-100

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 308.58  E-value: 1.89e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFRVDGGW----KSVVR---NMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKkTSrieGKVMLGGRD 89
Cdd:COG4608    6 PLLEVRDLKKHFPVRGGLfgrtVGVVKavdGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEP-TS---GEILFDGQD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  90 LLALPEEEMRKVRgKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRI-PNAKNRfddYPHQ 168
Cdd:COG4608   82 ITGLSGRELRPLR-RRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLrPEHADR---YPHE 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:COG4608  158 FSGGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIV 237

                        250       260
                 ....*....|....*....|....*
gi 549799341 249 ETGTTDDIFHRGRHPYTRALLSAVP 273
Cdd:COG4608  238 EIAPRDELYARPLHPYTQALLSAVP 262
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 315-569 2.02e-93

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 287.47  E-value: 2.02e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDK 394
Cdd:COG1124    2 LEVRNLSVSY-------GQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 ttlRTMRRSVQMIFQDPFASLDPRMSVGTAIMEPFIEHRLGtkqQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIA 474
Cdd:COG1124   75 ---KAFRRRVQMVFQDPYASLHPRHTVDRILAEPLRIHGLP---DREERIAELLEQVGLPPSFLDRYPHQLSGGQRQRVA 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 475 IARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFD 554
Cdd:COG1124  149 IARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLA 228

                        250
                 ....*....|....*
gi 549799341 555 NPQHPYTKKLMSAVP 569
Cdd:COG1124  229 GPKHPYTRELLAASL 243
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 312-574 2.57e-90

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 289.28  E-value: 2.57e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFdirsglfGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEP----TSGDVMLDGY 387
Cdd:COG4172    4 MPLLSVEDLSVAF-------GQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDpaahPSGSILFDGQ 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 388 EVLKLDKTTLRTMR-RSVQMIFQDPFASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLsPD---MMRRFPH 463
Cdd:COG4172   77 DLLGLSERELRRIRgNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGI-PDperRLDAYPH 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 464 EFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEI 543
Cdd:COG4172  156 QLSGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEI 235

                        250       260       270
                 ....*....|....*....|....*....|.
gi 549799341 544 VEIGPRAAVFDNPQHPYTKKLMSAVPVPDPA 574
Cdd:COG4172  236 VEQGPTAELFAAPQHPYTRKLLAAEPRGDPR 266
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 19-273 1.09e-79

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 252.03  E-value: 1.09e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLlalpEEEM 98
Cdd:COG1124    2 LEVRNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKS-TLLRALAGLERPWS---GEVTFDGRPV----TRRR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHqdiSSSAAKAEVIRLLEKVRIPNA-KNRfddYPHQFSGGMRQRV 177
Cdd:COG1124   74 RKAFRRRVQMVFQDPYASLHPRHTVDRILAEPLRIH---GLPDREERIAELLEQVGLPPSfLDR---YPHQLSGGQRQRV 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIF 257
Cdd:COG1124  148 AIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLL 227

                        250
                 ....*....|....*.
gi 549799341 258 HRGRHPYTRALLSAVP 273
Cdd:COG1124  228 AGPKHPYTRELLAASL 243
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
17-276 1.44e-79

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 254.83  E-value: 1.44e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIEGKVMLGGRDLLALPEE 96
Cdd:COG4170    2 PLLDIRNLTIEIDTPQGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNWHVTADRFRWNGIDLLKLSPR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  97 EMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISS-----SAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSG 171
Cdd:COG4170   82 ERRKIIGREIAMIFQEPSSCLDPSAKIGDQLIEAIPSWTFKGKwwqrfKWRKKRAIELLHRVGIKDHKDIMNSYPHELTE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 172 GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:COG4170  162 GECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESG 241

                        250       260
                 ....*....|....*....|....*
gi 549799341 252 TTDDIFHRGRHPYTRALLSAVPKLG 276
Cdd:COG4170  242 PTEQILKSPHHPYTKALLRSMPDFR 266
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 17-273 1.58e-79

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 254.63  E-value: 1.58e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFRVDGG----WK-----SVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdKKTsriEGKVMLGG 87
Cdd:PRK15079   7 VLLEVADLKVHFDIKDGkqwfWQppktlKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLV-KAT---DGEVAWLG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  88 RDLLALPEEEMRKVRgKDISMIFQEPMTSLNPIFPIGKQIAEAL-TVHQDISSSAAKAEVIRLLEKVRI-PNAKNRfddY 165
Cdd:PRK15079  83 KDLLGMKDDEWRAVR-SDIQMIFQDPLASLNPRMTIGEIIAEPLrTYHPKLSRQEVKDRVKAMMLKVGLlPNLINR---Y 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 166 PHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:PRK15079 159 PHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLG 238

                        250       260
                 ....*....|....*....|....*...
gi 549799341 246 DVVETGTTDDIFHRGRHPYTRALLSAVP 273
Cdd:PRK15079 239 HAVELGTYDEVYHNPLHPYTKALMSAVP 266
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
312-567 3.89e-78

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 248.60  E-value: 3.89e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFDIRSGLFGRKSgaVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYevlK 391
Cdd:COG4167    2 SALLEVRNLSKTFKYRTGLFRRQQ--FEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGH---K 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 392 LDKTTLRTMRRSVQMIFQDPFASLDPRMSVGTAIMEPFiehRLGTK---QQAREKAADLLEKVGLSPDMMRRFPHEFSGG 468
Cdd:COG4167   77 LEYGDYKYRCKHIRMIFQDPNTSLNPRLNIGQILEEPL---RLNTDltaEEREERIFATLRLVGLLPEHANFYPHMLSSG 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 469 QRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGP 548
Cdd:COG4167  154 QKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGK 233

                        250
                 ....*....|....*....
gi 549799341 549 RAAVFDNPQHPYTKKLMSA 567
Cdd:COG4167  234 TAEVFANPQHEVTKRLIES 252
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
 38-271 6.77e-78

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 246.51  E-value: 6.77e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   38 VRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIEGKVMLGGRDLLALpeeemrKVRGKDISMIFQEPMTSL 117
Cdd:TIGR02770   2 VQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLTQTSGEILLDGRPLLPL------SIRGRHIATIMQNPRTAF 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  118 NPIFPIGKQIAEALTVHQDISSSAaKAEVIRLLEKVRIPNAKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTT 197
Cdd:TIGR02770  76 NPLFTMGNHAIETLRSLGKLSKQA-RALILEALEAVGLPDPEEVLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTT 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341  198 ALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRGRHPYTRALLSA 271
Cdd:TIGR02770 155 DLDVVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLSA 228
PhnK COG4107
ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and ...
 17-272 3.96e-71

ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and metabolism];


Pssm-ID: 443283 [Multi-domain]  Cd Length: 262  Bit Score: 230.08  E-value: 3.96e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFrvDGGWKSVV--RNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKV-----MLGGRD 89
Cdd:COG4107    7 PLLSVRGLSKRY--GPGCGTVVacRDVSFDLYPGEVLGIVGESGSGKS----TLLKCLYFDLAPTSGSVyyrdrDGGPRD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  90 LLALPEEEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAknRFDDYPHQF 169
Cdd:COG4107   81 LFALSEAERRRLRRTDWGMVYQNPRDGLRMDVSAGGNIAERLMAAGERHYGDIRARALEWLERVEIPLE--RIDDLPRTF 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVE 249
Cdd:COG4107  159 SGGMQQRVQIARALVTNPRLLFLDEPTTGLDVSVQARLLDLIRRLQRELGLSMIVVTHDLGVIRLLADRTMVMKNGRVVE 238

                        250       260
                 ....*....|....*....|...
gi 549799341 250 TGTTDDIFHRGRHPYTRALLSAV 272
Cdd:COG4107  239 SGLTDQVLEDPQHPYTQLLVSSV 261
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 17-281 1.03e-70

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 231.39  E-value: 1.03e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFRVDGGW---KSVVR---NMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDL 90
Cdd:PRK11308   4 PLLQAIDLKKHYPVKRGLfkpERLVKaldGVSFTLERGKTLAVVGESGCGKS----TLARLLTMIETPTGGELYYQGQDL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  91 LAlPEEEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRI-PNAKNRfddYPHQF 169
Cdd:PRK11308  80 LK-ADPEAQKLLRQKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLrPEHYDR---YPHMF 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVE 249
Cdd:PRK11308 156 SGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVE 235

                        250       260       270
                 ....*....|....*....|....*....|..
gi 549799341 250 TGTTDDIFHRGRHPYTRALLSAVPKLGSMKER 281
Cdd:PRK11308 236 KGTKEQIFNNPRHPYTQALLSATPRLNPDDRR 267
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 314-578 1.22e-66

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 218.52  E-value: 1.22e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  314 ILSVKDLTTRFdiRSGLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLD 393
Cdd:TIGR02769   2 LLEVRDVTHTY--RTGGLFGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  394 KTTLRTMRRSVQMIFQDPFASLDPRMSVGTAIMEPfIEHRLGTKQQARE-KAADLLEKVGLSPDMMRRFPHEFSGGQRQR 472
Cdd:TIGR02769  80 RKQRRAFRRDVQLVFQDSPSAVNPRMTVRQIIGEP-LRHLTSLDESEQKaRIAELLDMVGLRSEDADKLPRQLSGGQLQR 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  473 IAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAV 552
Cdd:TIGR02769 159 INIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQL 238

                         250       260
                  ....*....|....*....|....*.
gi 549799341  553 FDNpQHPYTKKLMSAVPVPDPARRQI 578
Cdd:TIGR02769 239 LSF-KHPAGRNLQSAVLPEHPVRRSI 263
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 308-569 6.14e-64

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 213.82  E-value: 6.14e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 308 SGGRTPILSVKDLTTRFdirsglfGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEP---TSGDVML 384
Cdd:PRK09473   6 QQQADALLDVKDLRVTF-------STPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAAngrIGGSATF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 385 DGYEVLKLDKTTLRTMR-RSVQMIFQDPFASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLsPDM---MRR 460
Cdd:PRK09473  79 NGREILNLPEKELNKLRaEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKM-PEArkrMKM 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 461 FPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYL 540
Cdd:PRK09473 158 YPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYA 237

                        250       260
                 ....*....|....*....|....*....
gi 549799341 541 GEIVEIGPRAAVFDNPQHPYTKKLMSAVP 569
Cdd:PRK09473 238 GRTMEYGNARDVFYQPSHPYSIGLLNAVP 266
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 17-273 6.74e-62

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 216.26  E-value: 6.74e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFRVDGGWKS-------VVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRD 89
Cdd:PRK10261 312 PILQVRNLVTRFPLRSGLLNrvtrevhAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQ----GGEIIFNGQR 387

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  90 LLALPEEEMRKVRgKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRI-PNAKNRfddYPHQ 168
Cdd:PRK10261 388 IDTLSPGKLQALR-RDIQFIFQDPYASLDPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLlPEHAWR---YPHE 463

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:PRK10261 464 FSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIV 543

                        250       260
                 ....*....|....*....|....*
gi 549799341 249 ETGTTDDIFHRGRHPYTRALLSAVP 273
Cdd:PRK10261 544 EIGPRRAVFENPQHPYTRKLMAAVP 568
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
312-577 2.97e-61

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 204.54  E-value: 2.97e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFdiRSGLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLK 391
Cdd:PRK10419   1 MTLLNVSGLSHHY--AHGGLSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAK 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 392 LDKTTLRTMRRSVQMIFQDPFASLDPRMSVGTAIMEPfIEHRLGTKQQARE-KAADLLEKVGLSPDMMRRFPHEFSGGQR 470
Cdd:PRK10419  79 LNRAQRKAFRRDIQMVFQDSISAVNPRKTVREIIREP-LRHLLSLDKAERLaRASEMLRAVDLDDSVLDKRPPQLSGGQL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 471 QRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVE---IG 547
Cdd:PRK10419 158 QRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVEtqpVG 237

                        250       260       270
                 ....*....|....*....|....*....|
gi 549799341 548 PRAAVfdnpQHPYTKKLMSAVPVPDPARRQ 577
Cdd:PRK10419 238 DKLTF----SSPAGRVLQNAVLPAFPVRRR 263
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
15-271 1.11e-57

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 194.67  E-value: 1.11e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  15 VSPVLSVQNLTTSFRVDGGW-----KSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRD 89
Cdd:COG4167    1 MSALLEVRNLSKTFKYRTGLfrrqqFEAVKPVSFTLEAGQTLAIIGENGSGKS----TLAKMLAGIIEPTSGEILINGHK 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  90 LlalpEEEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRI-PNAKNrfdDYPHQ 168
Cdd:COG4167   77 L----EYGDYKYRCKHIRMIFQDPNTSLNPRLNIGQILEEPLRLNTDLTAEEREERIFATLRLVGLlPEHAN---FYPHM 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:COG4167  150 LSSGQKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVV 229

                        250       260
                 ....*....|....*....|...
gi 549799341 249 ETGTTDDIFHRGRHPYTRALLSA 271
Cdd:COG4167  230 EYGKTAEVFANPQHEVTKRLIES 252
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 314-568 2.46e-56

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 190.21  E-value: 2.46e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLkLD 393
Cdd:COG1126    1 MIEIENLHKSF-----------GDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLT-DS 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 KTTLRTMRRSVQMIFQDpFaSLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRI 473
Cdd:COG1126   69 KKDINKLRRKVGMVFQQ-F-NLFPHLTVLENVTLAPIKVKKMSKAEAEERAMELLERVGLA-DKADAYPAQLSGGQQQRV 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 474 AIARSLMLDPKVIVADEAVSALD-----------VSIKAQ----VCnllldlqqnlnlaflfISHDMAVVERVSHRVAVM 538
Cdd:COG1126  146 AIARALAMEPKVMLFDEPTSALDpelvgevldvmRDLAKEgmtmVV----------------VTHEMGFAREVADRVVFM 209

                        250       260       270
                 ....*....|....*....|....*....|
gi 549799341 539 YLGEIVEIGPRAAVFDNPQHPYTKKLMSAV 568
Cdd:COG1126  210 DGGRIVEEGPPEEFFENPQHERTRAFLSKV 239
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
314-567 3.17e-56

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 191.16  E-value: 3.17e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFDIRSGLFGRKSgaVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEvLKLD 393
Cdd:PRK15112   4 LLEVRNLSKTFRYRTGWFRRQT--VEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHP-LHFG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 KTTLRTMRrsVQMIFQDPFASLDPRMSVGTAIMEPFiehRLGTK--QQAREKAADL-LEKVGLSPDMMRRFPHEFSGGQR 470
Cdd:PRK15112  81 DYSYRSQR--IRMIFQDPSTSLNPRQRISQILDFPL---RLNTDlePEQREKQIIEtLRQVGLLPDHASYYPHMLAPGQK 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 471 QRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRA 550
Cdd:PRK15112 156 QRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTA 235

                        250
                 ....*....|....*..
gi 549799341 551 AVFDNPQHPYTKKLMSA 567
Cdd:PRK15112 236 DVLASPLHELTKRLIAG 252
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
17-291 4.08e-56

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 192.71  E-value: 4.08e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLlDKKTSRIEGKVM-LGGRDLLALPE 95
Cdd:PRK15093   2 PLLDIRNLTIEFKTSDGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGV-TKDNWRVTADRMrFDDIDLLRLSP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTV-------HQDISSSAAKAevIRLLEKVRIPNAKNRFDDYPHQ 168
Cdd:PRK15093  81 RERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPGwtykgrwWQRFGWRKRRA--IELLHRVGIKDHKDAMRSFPYE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:PRK15093 159 LTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTV 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 549799341 249 ETGTTDDIFHRGRHPYTRALLSAVPKLGSM---KERL--LPARFPIID 291
Cdd:PRK15093 239 ETAPSKELVTTPHHPYTQALIRAIPDFGSAmphKSRLntLPGAIPLLE 286
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 331-569 1.51e-55

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 191.11  E-value: 1.51e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 331 FGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEpTSGDVMLDGYEVLKLDKTTLRTMRR------SV 404
Cdd:PRK11022  13 FGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLID-YPGRVMAEKLEFNGQDLQRISEKERrnlvgaEV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 405 QMIFQDPFASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLsPDMMRR---FPHEFSGGQRQRIAIARSLML 481
Cdd:PRK11022  92 AMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGI-PDPASRldvYPHQLSGGMSQRVMIAMAIAC 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 482 DPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYT 561
Cdd:PRK11022 171 RPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAPRHPYT 250


                 ....*...
gi 549799341 562 KKLMSAVP 569
Cdd:PRK11022 251 QALLRALP 258
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 312-573 1.52e-55

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 196.85  E-value: 1.52e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFdirsglfgRKSGAVH-AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRL-----IEPTSGDVMLD 385
Cdd:PRK15134   3 QPLLAIENLSVAF--------RQQQTVRtVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLlpsppVVYPSGDIRFH 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 386 GYEVLKLDKTTLRTMR-RSVQMIFQDPFASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGL--SPDMMRRFP 462
Cdd:PRK15134  75 GESLLHASEQTLRGVRgNKIAMIFQEPMVSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIrqAAKRLTDYP 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 463 HEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGE 542
Cdd:PRK15134 155 HQLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGR 234

                        250       260       270
                 ....*....|....*....|....*....|.
gi 549799341 543 IVEIGPRAAVFDNPQHPYTKKLMSAVPVPDP 573
Cdd:PRK15134 235 CVEQNRAATLFSAPTHPYTQKLLNSEPSGDP 265
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
331-580 2.34e-55

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 191.06  E-value: 2.34e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 331 FGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQD 410
Cdd:COG1135   11 FPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRAARRKIGMIFQH 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 411 pFASLDPRmsvgTA---IMEPFiEHrLGT-KQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVI 486
Cdd:COG1135   91 -FNLLSSR----TVaenVALPL-EI-AGVpKAEIRKRVAELLELVGLS-DKADAYPSQLSGGQKQRVGIARALANNPKVL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 487 VADEAVSALD-------------------VSIkaqvcnllldlqqnlnlafLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:COG1135  163 LCDEATSALDpettrsildllkdinrelgLTI-------------------VLITHEMDVVRRICDRVAVLENGRIVEQG 223

                        250       260       270
                 ....*....|....*....|....*....|...
gi 549799341 548 PRAAVFDNPQHPYTKKLMSAVPVPDPARRQIKR 580
Cdd:COG1135  224 PVLDVFANPQSELTRRFLPTVLNDELPEELLAR 256
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
19-327 2.57e-55

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 191.06  E-value: 2.57e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEM 98
Cdd:COG1135    2 IELENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKS-TLIRCINLLERPTS---GSVLVDGVDLTALSEREL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRgKDISMIFQEP--MTSLNpifpIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIpnaKNRFDDYPHQFSGGMRQR 176
Cdd:COG1135   78 RAAR-RKIGMIFQHFnlLSSRT----VAENVALPLEI-AGVPKAEIRKRVAELLELVGL---SDKADAYPSQLSGGQKQR 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 177 VMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:COG1135  149 VGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDV 228

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341 257 FHRGRHPYTRALLSAVPKLGsmkerlLPARFPIIDIKTGESQPVADVKDTVSGGRTPILSvkDLTTRFDIR 327
Cdd:COG1135  229 FANPQSELTRRFLPTVLNDE------LPEELLARLREAAGGGRLVRLTFVGESADEPLLS--ELARRFGVD 291
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 17-272 2.00e-54

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 185.90  E-value: 2.00e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFRVDGGwksvVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGR-----DLL 91
Cdd:PRK11701   5 PLLSVRGLTKLYGPRKG----CRDVSFDLYPGEVLGIVGESGSGKT----TLLNALSARLAPDAGEVHYRMRdgqlrDLY 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  92 ALPEEEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTV-----HQDISSSAAkaeviRLLEKVRIPnaKNRFDDYP 166
Cdd:PRK11701  77 ALSEAERRRLLRTEWGFVHQHPRDGLRMQVSAGGNIGERLMAvgarhYGDIRATAG-----DWLERVEID--AARIDDLP 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 167 HQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGD 246
Cdd:PRK11701 150 TTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGR 229

                        250       260
                 ....*....|....*....|....*.
gi 549799341 247 VVETGTTDDIFHRGRHPYTRALLSAV 272
Cdd:PRK11701 230 VVESGLTDQVLDDPQHPYTQLLVSSV 255
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 38-271 6.38e-54

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 184.52  E-value: 6.38e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  38 VRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIEGKVMLGGRDLLAlpeeemRKVRGKDISMIFQEPMTSL 117
Cdd:PRK10418  19 VHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAGVRQTAGRVLLDGKPVAP------CALRGRKIATIMQNPRSAF 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 118 NPIFPIGKQIAEALtvhQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTT 197
Cdd:PRK10418  93 NPLHTMHTHARETC---LALGKPADDATLTAALEAVGLENAARVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTT 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 198 ALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRGRHPYTRALLSA 271
Cdd:PRK10418 170 DLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTRSLVSA 243
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
16-249 6.59e-54

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 183.32  E-value: 6.59e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPE 95
Cdd:COG1136    2 SPLLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKS-TLLNILGGLDRPTS---GEVLIDGQDISSLSE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGKDISMIFQEPmtSLNPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIpnaKNRFDDYPHQFSGGMRQ 175
Cdd:COG1136   78 RELARLRRRHIGFVFQFF--NLLPELTALENVALPLLL-AGVSRKERRERARELLERVGL---GDRLDHRPSQLSGGQQQ 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMgVVAEVSDRTIVMFRGDVVE 249
Cdd:COG1136  152 RVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDP-ELAARADRVIRLRDGRIVS 224
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 18-272 1.81e-53

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 182.50  E-value: 1.81e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLAlPEEE 97
Cdd:COG1126    1 MIEIENLHKSF----GDLEVLKGISLDVEKGEVVVIIGPSGSGKS-TLLRCINLLEEPDS---GTITVDGEDLTD-SKKD 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 MRKVRgKDISMIFQE----P-MTSL-NpifpigkqIAEALTVHQDISSSAAKAEVIRLLEKVRIPNaknRFDDYPHQFSG 171
Cdd:COG1126   72 INKLR-RKVGMVFQQfnlfPhLTVLeN--------VTLAPIKVKKMSKAEAEERAMELLERVGLAD---KADAYPAQLSG 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 172 GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:COG1126  140 GQQQRVAIARALAMEPKVMLFDEPTSALDPELVGEVLDVMRDLA-KEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEG 218

                        250       260
                 ....*....|....*....|.
gi 549799341 252 TTDDIFHRGRHPYTRALLSAV 272
Cdd:COG1126  219 PPEEFFENPQHERTRAFLSKV 239
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 19-242 1.13e-52

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 179.61  E-value: 1.13e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEM 98
Cdd:cd03255    1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKS-TLLNILGGLDRPTS---GEVRVDGTDISKLSEKEL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGKDISMIFQEPmtSLNPIFPIGKQIAEALTVHQdISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVM 178
Cdd:cd03255   77 AAFRRRHIGFVFQSF--NLLPDLTALENVELPLLLAG-VPKKERRERAEELLERVGLGDRLNH---YPSELSGGQQQRVA 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMgVVAEVSDRTIVM 242
Cdd:cd03255  151 IARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDP-ELAEYADRIIEL 213
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 19-552 1.56e-51

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 185.78  E-value: 1.56e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   19 LSVQNLTTSFrvDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSVTsLSIMRLLD------------------------- 73
Cdd:TIGR03269   1 IEVKNLTKKF--DG--KEVLKNISFTIEEGEVLGILGRSGAGKSVL-MHVLRGMDqyeptsgriiyhvalcekcgyverp 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   74 ----KKTSRIEGKVMLGGRDLLALPEEEMRKVRgKDISMIFQEPMtSLNPIFPIGKQIAEALtvhQDISSSAAKAeVIRL 149
Cdd:TIGR03269  76 skvgEPCPVCGGTLEPEEVDFWNLSDKLRRRIR-KRIAIMLQRTF-ALYGDDTVLDNVLEAL---EEIGYEGKEA-VGRA 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  150 LEKVRIPNAKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDM 229
Cdd:TIGR03269 150 VDLIEMVQLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWP 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  230 GVVAEVSDRTIVMFRGDVVETGTTDDIFHRgrhpytraLLSAVPKLGSMKErllparfpiidIKTGEsqpvadvkdtvsg 309
Cdd:TIGR03269 230 EVIEDLSDKAIWLENGEIKEEGTPDEVVAV--------FMEGVSEVEKECE-----------VEVGE------------- 277

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  310 grtPILSVKDLTTRFdirsglFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDV-MLDGYE 388
Cdd:TIGR03269 278 ---PIIKVRNVSKRY------ISVDRGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVnVRVGDE 348

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  389 VLklDKTTLRTMRRS-----VQMIFQDpfASLDPRMSVGTAIMEPfIEHRLgTKQQAREKAADLLEKVGLSPD----MMR 459
Cdd:TIGR03269 349 WV--DMTKPGPDGRGrakryIGILHQE--YDLYPHRTVLDNLTEA-IGLEL-PDELARMKAVITLKMVGFDEEkaeeILD 422

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  460 RFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMY 539
Cdd:TIGR03269 423 KYPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMR 502

                         570
                  ....*....|...
gi 549799341  540 LGEIVEIGPRAAV 552
Cdd:TIGR03269 503 DGKIVKIGDPEEI 515
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 22-300 1.89e-51

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 180.77  E-value: 1.89e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  22 QNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEMRKV 101
Cdd:PRK11153   5 KNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKS-TLIRCINLLERPTS---GRVLVDGQDLTALSEKELRKA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 102 RgKDISMIFQE-PMTSLNPIFpigKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVMIA 180
Cdd:PRK11153  81 R-RQIGMIFQHfNLLSSRTVF---DNVALPLEL-AGTPKAEIKARVTELLELVGLSDKADR---YPAQLSGGQKQRVAIA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 181 MALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRG 260
Cdd:PRK11153 153 RALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHP 232

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 549799341 261 RHPYTRALLSAV-------PKLGSMKERLLPARFPIIDIK-TGES--QPV 300
Cdd:PRK11153 233 KHPLTREFIQSTlhldlpeDYLARLQAEPTTGSGPLLRLEfTGESvdAPL 282
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 17-272 3.11e-51

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 177.33  E-value: 3.11e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   17 PVLSVQNLTTSFrvdGGWKSVvRNMSFEIAPRETVAIVGESGSGKS--VTSLSIMRLLDKKTSRIEGKVMlGGRDLLALP 94
Cdd:TIGR02323   2 PLLQVSGLSKSY---GGGKGC-RDVSFDLYPGEVLGIVGESGSGKStlLGCLAGRLAPDHGTATYIMRSG-AELELYQLS 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   95 EEEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPnaKNRFDDYPHQFSGGMR 174
Cdd:TIGR02323  77 EAERRRLMRTEWGFVHQNPRDGLRMRVSAGANIGERLMAIGARHYGNIRATAQDWLEEVEID--PTRIDDLPRAFSGGMQ 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  175 QRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTD 254
Cdd:TIGR02323 155 QRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESGLTD 234

                         250
                  ....*....|....*...
gi 549799341  255 DIFHRGRHPYTRALLSAV 272
Cdd:TIGR02323 235 QVLDDPQHPYTQLLVSSI 252
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 18-257 6.52e-51

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 175.46  E-value: 6.52e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEE 97
Cdd:cd03258    1 MIELKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKS-TLIRCINGLERPTS---GSVLVDGTDLTLLSGKE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 MRKVRgKDISMIFQE--PMTSLNpifpIGKQIAEALTVHQdISSSAAKAEVIRLLEKVripNAKNRFDDYPHQFSGGMRQ 175
Cdd:cd03258   77 LRKAR-RRIGMIFQHfnLLSSRT----VFENVALPLEIAG-VPKAEIEERVLELLELV---GLEDKADAYPAQLSGGQKQ 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDD 255
Cdd:cd03258  148 RVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEE 227


                 ..
gi 549799341 256 IF 257
Cdd:cd03258  228 VF 229
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 331-568 1.21e-50

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 178.46  E-value: 1.21e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 331 FGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQD 410
Cdd:PRK11153  11 FPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRKARRQIGMIFQH 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 411 pFASLDPRMSVGTAIMEPFIEHRlgTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:PRK11153  91 -FNLLSSRTVFDNVALPLELAGT--PKAEIKARVTELLELVGLS-DKADRYPAQLSGGQKQRVAIARALASNPKVLLCDE 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 491 AVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAV 568
Cdd:PRK11153 167 ATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPKHPLTREFIQST 244
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 17-269 1.98e-50

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 174.40  E-value: 1.98e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFrvdGGwKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdKKTSrieGKVMLGGRDLLALPEE 96
Cdd:COG1127    4 PMIEVRNLTKSF---GD-RVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLL-RPDS---GEILVDGQDITGLSEK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  97 EMRKVRgKDISMIFQEP--MTSLNpifpIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMR 174
Cdd:COG1127   76 ELYELR-RRIGMLFQGGalFDSLT----VFENVAFPLREHTDLSEAEIRELVLEKLELVGLPGAADK---MPSELSGGMR 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 175 QRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTD 254
Cdd:COG1127  148 KRVALARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPE 227

                        250
                 ....*....|....*
gi 549799341 255 DIFHRGrHPYTRALL 269
Cdd:COG1127  228 ELLASD-DPWVRQFL 241
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 331-557 4.31e-50

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 173.54  E-value: 4.31e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 331 FGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQD 410
Cdd:cd03258   11 FGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELRKARRRIGMIFQH 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 411 pFASLDPRmSVGTAIMEPFIEHRLGtKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:cd03258   91 -FNLLSSR-TVFENVALPLEIAGVP-KAEIEERVLELLELVGLE-DKADAYPAQLSGGQKQRVGIARALANNPKVLLCDE 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 491 AVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQ 557
Cdd:cd03258  167 ATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANPQ 233
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
313-569 7.38e-50

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 175.86  E-value: 7.38e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFDIRSGLfgrksgaVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPT---SGDVM-LDGYE 388
Cdd:COG4170    2 PLLDIRNLTIEIDTPQGR-------VKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNwhvTADRFrWNGID 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 389 VLKLDKTTLRT-MRRSVQMIFQDPFASLDPRMSVGTAIMEPFIEHRLGTK-----QQAREKAADLLEKVGL--SPDMMRR 460
Cdd:COG4170   75 LLKLSPRERRKiIGREIAMIFQEPSSCLDPSAKIGDQLIEAIPSWTFKGKwwqrfKWRKKRAIELLHRVGIkdHKDIMNS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 461 FPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYL 540
Cdd:COG4170  155 YPHELTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYC 234

                        250       260
                 ....*....|....*....|....*....
gi 549799341 541 GEIVEIGPRAAVFDNPQHPYTKKLMSAVP 569
Cdd:COG4170  235 GQTVESGPTEQILKSPHHPYTKALLRSMP 263
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 18-272 9.63e-49

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 170.76  E-value: 9.63e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   18 VLSVQNLTTSFRVDG-----GWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLA 92
Cdd:TIGR02769   2 LLEVRDVTHTYRTGGlfgakQRAPVLTNVSLSIEEGETVGLLGRSGCGKS----TLARLLLGLEKPAQGTVSFRGQDLYQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   93 LPEEEMRKVRgKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNakNRFDDYPHQFSGG 172
Cdd:TIGR02769  78 LDRKQRRAFR-RDVQLVFQDSPSAVNPRMTVRQIIGEPLRHLTSLDESEQKARIAELLDMVGLRS--EDADKLPRQLSGG 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  173 MRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGT 252
Cdd:TIGR02769 155 QLQRINIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECD 234

                         250       260
                  ....*....|....*....|
gi 549799341  253 TDDIFHRgRHPYTRALLSAV 272
Cdd:TIGR02769 235 VAQLLSF-KHPAGRNLQSAV 253
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
16-286 4.50e-48

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 169.10  E-value: 4.50e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFRVDG-----GWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDL 90
Cdd:PRK10419   1 MTLLNVSGLSHHYAHGGlsgkhQHQTVLNNVSLSLKSGETVALLGRSGCGKS----TLARLLVGLESPSQGNVSWRGEPL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  91 LALPEEEMRKVRgKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKnrFDDYPHQFS 170
Cdd:PRK10419  77 AKLNRAQRKAFR-RDIQMVFQDSISAVNPRKTVREIIREPLRHLLSLDKAERLARASEMLRAVDLDDSV--LDKRPPQLS 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 171 GGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVET 250
Cdd:PRK10419 154 GGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVET 233

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 549799341 251 GTTDDIFHRgRHPYTRALLSAVpklgsmkerlLPAR 286
Cdd:PRK10419 234 QPVGDKLTF-SSPAGRVLQNAV----------LPAF 258
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 311-562 7.99e-48

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 167.46  E-value: 7.99e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 311 RTPILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVL 390
Cdd:COG1127    2 SEPMIEVRNLTKSF-----------GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDIT 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 391 KLDKTTLRTMRRSVQMIFQDP--FASldprMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLsPDMMRRFPHEFSGG 468
Cdd:COG1127   71 GLSEKELYELRRRIGMLFQGGalFDS----LTVFENVAFPLREHTDLSEAEIRELVLEKLELVGL-PGAADKMPSELSGG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 469 QRQRIAIARSLMLDPKVIVADEAVSALD-----------VSIKAQvcnllldlqqnLNLAFLFISHDMAVVERVSHRVAV 537
Cdd:COG1127  146 MRKRVALARALALDPEILLYDEPTAGLDpitsavideliRELRDE-----------LGLTSVVVTHDLDSAFAIADRVAV 214

                        250       260
                 ....*....|....*....|....*
gi 549799341 538 MYLGEIVEIGPRAAVFDNPqHPYTK 562
Cdd:COG1127  215 LADGKIIAEGTPEELLASD-DPWVR 238
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 311-560 3.45e-47

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 169.51  E-value: 3.45e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 311 RTPILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVl 390
Cdd:COG3842    2 AMPALELENVSKRY-----------GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDV- 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 391 kldkTTLRTMRRSVQMIFQDpFAsLDPRMSVGTAIMEPfIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQR 470
Cdd:COG3842   70 ----TGLPPEKRNVGMVFQD-YA-LFPHLTVAENVAFG-LRMRGVPKAEIRARVAELLELVGLE-GLADRYPHQLSGGQQ 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 471 QRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHD----MAvverVSHRVAVMYLGEIVEI 546
Cdd:COG3842  142 QRVALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDqeeaLA----LADRIAVMNDGRIEQV 217

                        250
                 ....*....|....
gi 549799341 547 GPRAAVFDNPQHPY 560
Cdd:COG3842  218 GTPEEIYERPATRF 231
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 313-552 1.58e-46

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 164.46  E-value: 1.58e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFDirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKL 392
Cdd:COG3638    1 PMLELRNLSKRYP----------GGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTAL 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 393 DKTTLRTMRRSVQMIFQDPfaSLDPRMSVGTAIMepfieH-RLGTK-----------QQAREKAADLLEKVGLSPDMMRR 460
Cdd:COG3638   71 RGRALRRLRRRIGMIFQQF--NLVPRLSVLTNVL-----AgRLGRTstwrsllglfpPEDRERALEALERVGLADKAYQR 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 461 fPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYL 540
Cdd:COG3638  144 -ADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLRD 222

                        250
                 ....*....|..
gi 549799341 541 GEIVEIGPRAAV 552
Cdd:COG3638  223 GRVVFDGPPAEL 234
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 19-266 1.62e-46

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 163.83  E-value: 1.62e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVtslsIMRL---LDKKTSrieGKVMLGGRDLLALPE 95
Cdd:cd03261    1 IELRGLTKSF----GGRTVLKGVDLDVRRGEILAIIGPSGSGKST----LLRLivgLLRPDS---GEVLIDGEDISGLSE 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRgKDISMIFQEP--MTSLNpifpIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGM 173
Cdd:cd03261   70 AELYRLR-RRMGMLFQSGalFDSLT----VFENVAFPLREHTRLSEEEIREIVLEKLEAVGLRGAEDL---YPAELSGGM 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 174 RQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTT 253
Cdd:cd03261  142 KKRVALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTP 221

                        250
                 ....*....|...
gi 549799341 254 DDIFHRgRHPYTR 266
Cdd:cd03261  222 EELRAS-DDPLVR 233
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 333-570 1.86e-46

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 164.74  E-value: 1.86e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 333 RKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRR-SVQMIFQDp 411
Cdd:cd03294   32 KKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELRRkKISMVFQS- 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 412 FAsLDPRMSVGTAIMEPfIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEA 491
Cdd:cd03294  111 FA-LLPHRTVLENVAFG-LEVQGVPRAEREERAAEALELVGLE-GWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEA 187

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 492 VSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAVPV 570
Cdd:cd03294  188 FSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFFRGVDR 266
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 336-547 9.56e-46

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 161.15  E-value: 9.56e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldkTTLRTMRRSVQMIFQDPfaSL 415
Cdd:cd03259   11 GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDV-----TGVPPERRNIGMVFQDY--AL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAIMEPfIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSAL 495
Cdd:cd03259   84 FPHLTVAENIAFG-LKLRGVPKAEIRARVRELLELVGLE-GLLNRYPHELSGGQQQRVALARALAREPSLLLLDEPLSAL 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 549799341 496 DVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:cd03259  162 DAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 340-560 9.90e-46

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 162.08  E-value: 9.90e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRtmrRSVQMIFQDpfASLDPRM 419
Cdd:cd03295   16 AVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELR---RKIGYVIQQ--IGLFPHM 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 420 SVGTAI-MEPFIEHRLgtKQQAREKAADLLEKVGLSPD-MMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:cd03295   91 TVEENIaLVPKLLKWP--KEKIRERADELLALVGLDPAeFADRYPHELSGGQQQRVGVARALAADPPLLLMDEPFGALDP 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 498 SIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPY 560
Cdd:cd03295  169 ITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDF 231
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 315-538 2.54e-45

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 159.94  E-value: 2.54e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldk 394
Cdd:cd03293    1 LEVRNVSKTY-------GGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPV----- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 ttlRTMRRSVQMIFQDPfaSLDPRMSVGTAIMEPfIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIA 474
Cdd:cd03293   69 ---TGPGPDRGYVFQQD--ALLPWLTVLDNVALG-LELQGVPKAEARERAEELLELVGLS-GFENAYPHQLSGGMRQRVA 141

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 475 IARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDM--AVveRVSHRVAVM 538
Cdd:cd03293  142 LARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIdeAV--FLADRVVVL 205
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 19-242 3.11e-45

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 159.94  E-value: 3.11e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLlalpeeem 98
Cdd:cd03293    1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKS-TLLRIIAGLERPTS---GEVLVDGEPV-------- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 rKVRGKDISMIFQEPmtSLNPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVM 178
Cdd:cd03293   69 -TGPGPDRGYVFQQD--ALLPWLTVLDNVALGLEL-QGVPKAEARERAEELLELVGLSGFENA---YPHQLSGGMRQRVA 141

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVM 242
Cdd:cd03293  142 LARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 19-259 3.89e-45

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 159.81  E-value: 3.89e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLttSFRVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdKKTSrieGKVMLGGRDLLalpEEEM 98
Cdd:COG1122    1 IELENL--SFSYPGG-TPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLL-KPTS---GEVLVDGKDIT---KKNL 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRgKDISMIFQEPMTslnpifpigkQIAEAlTVHQDI---------SSSAAKAEVIRLLEKVRIPNAKNRfddYPHQF 169
Cdd:COG1122   71 RELR-RKVGLVFQNPDD----------QLFAP-TVEEDVafgpenlglPREEIRERVEEALELVGLEHLADR---PPHEL 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVE 249
Cdd:COG1122  136 SGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLN-KEGKTVIIVTHDLDLVAELADRVIVLDDGRIVA 214

                        250
                 ....*....|
gi 549799341 250 TGTTDDIFHR 259
Cdd:COG1122  215 DGTPREVFSD 224
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 331-543 2.06e-44

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 157.65  E-value: 2.06e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 331 FGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRR-SVQMIFQ 409
Cdd:cd03255   10 YGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFRRrHIGFVFQ 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 410 DPfaSLDPRMSVGTAIMEPFIEHRLGtKQQAREKAADLLEKVGLsPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVAD 489
Cdd:cd03255   90 SF--NLLPDLTALENVELPLLLAGVP-KKERRERAEELLERVGL-GDRLNHYPSELSGGQQQRVAIARALANDPKIILAD 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 549799341 490 EAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEI 543
Cdd:cd03255  166 EPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEY-ADRIIELRDGKI 218
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
 333-568 2.45e-44

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 161.94  E-value: 2.45e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  333 RKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRR-SVQMIFQDp 411
Cdd:TIGR01186   1 KKTGGKKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMKQSPVELREVRRkKIGMVFQQ- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  412 FAsLDPRMSVGTAImePFIEHRLG-TKQQAREKAADLLEKVGLsPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:TIGR01186  80 FA-LFPHMTILQNT--SLGPELLGwPEQERKEKALELLKLVGL-EEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDE 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341  491 AVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAV 568
Cdd:TIGR01186 156 AFSALDPLIRDSMQDELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIGKV 233
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 14-254 4.76e-44

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 157.21  E-value: 4.76e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  14 SVSPVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLAL 93
Cdd:COG4181    4 SSAPIIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKS-TLLGLLAGLDRPTS---GTVRLAGQDLFAL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  94 PEEEMRKVRGKDISMIFQE----P-MTSL-NPIFPigkqiAEaLTVHQDissSAAKAEviRLLEKVRIpnaKNRFDDYPH 167
Cdd:COG4181   80 DEDARARLRARHVGFVFQSfqllPtLTALeNVMLP-----LE-LAGRRD---ARARAR--ALLERVGL---GHRLDHYPA 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 168 QFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGvVAEVSDRTIVMFRGDV 247
Cdd:COG4181  146 QLSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPA-LAARCDRVLRLRAGRL 224


                 ....*..
gi 549799341 248 VETGTTD 254
Cdd:COG4181  225 VEDTAAT 231
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 18-272 6.01e-44

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 157.51  E-value: 6.01e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLttSFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPeee 97
Cdd:COG1120    1 MLEAENL--SVGYGG--RPVLDDVSLSLPPGEVTALLGPNGSGKS----TLLRALAGLLKPSSGEVLLDGRDLASLS--- 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 mRKVRGKDISMIFQEPmtslnpifpigkQIAEALTV----------HQDI---SSSAAKAEVIRLLEKVRIPNAKNRfdd 164
Cdd:COG1120   70 -RRELARRIAYVPQEP------------PAPFGLTVrelvalgrypHLGLfgrPSAEDREAVEEALERTGLEHLADR--- 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 165 YPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFR 244
Cdd:COG1120  134 PVDELSGGERQRVLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKD 213

                        250       260
                 ....*....|....*....|....*...
gi 549799341 245 GDVVETGTTDDIFhrgrhpyTRALLSAV 272
Cdd:COG1120  214 GRIVAQGPPEEVL-------TPELLEEV 234
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 40-257 1.68e-43

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 156.84  E-value: 1.68e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   40 NMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEMRKVRgKDISMIFQepmtslnp 119
Cdd:TIGR04521  23 DVSLTIEDGEFVAIIGHTGSGKS-TLIQHLNGLLKPTS---GTVTIDGRDITAKKKKKLKDLR-KKVGLVFQ-------- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  120 iFPiGKQIAEAlTVHQDI---------SSSAAKAEVIRLLEKVRIPnaknrfDDY----PHQFSGGMRQRVMIAMALASK 186
Cdd:TIGR04521  90 -FP-EHQLFEE-TVYKDIafgpknlglSEEEAEERVKEALELVGLD------EEYlersPFELSGGQMRRVAIAGVLAME 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341  187 PKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIF 257
Cdd:TIGR04521 161 PEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVF 231
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 20-245 2.22e-43

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 154.55  E-value: 2.22e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  20 SVQNLttSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEMR 99
Cdd:cd03225    1 ELKNL--SFSYPDGARPALDDISLTIKKGEFVLIVGPNGSGKS----TLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 100 KvrgkDISMIFQEPMTslnpifpigkQIAeALTVHQDISSSA---------AKAEVIRLLEKVRIPNAKNRfddYPHQFS 170
Cdd:cd03225   75 R----KVGLVFQNPDD----------QFF-GPTVEEEVAFGLenlglpeeeIEERVEEALELVGLEGLRDR---SPFTLS 136

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 171 GGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:cd03225  137 GGQKQRVAIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLK-AEGKTIIIVTHDLDLLLELADRVIVLEDG 210
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
312-545 2.44e-43

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 154.82  E-value: 2.44e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFdirsglfGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLK 391
Cdd:COG1136    2 SPLLELRNLTKSY-------GTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISS 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 392 LDKTTLRTMRR-SVQMIFQDPFasLDPRMSVGTAIMEPFIEHRLGtKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQR 470
Cdd:COG1136   75 LSERELARLRRrHIGFVFQFFN--LLPELTALENVALPLLLAGVS-RKERRERARELLERVGLG-DRLDHRPSQLSGGQQ 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 471 QRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEIVE 545
Cdd:COG1136  151 QRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELAAR-ADRVIRLRDGRIVS 224
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 17-242 3.09e-43

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 155.63  E-value: 3.09e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRL---LDKKTSrieGKVMLGGRDLLAL 93
Cdd:COG1116    6 PALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKS----TLLRLiagLEKPTS---GEVLVDGKPVTGP 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  94 peeemrkvrGKDISMIFQEPmtSLnpiFP---IGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFS 170
Cdd:COG1116   79 ---------GPDRGVVFQEP--AL---LPwltVLDNVALGLEL-RGVPKAERRERARELLELVGLAGFEDA---YPHQLS 140

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 171 GGMRQRVMIAMALASKPKLLIADEPTTALDV----TIQGQILDliktLQEEEGMSVLFITHDmgvVAE---VSDRTIVM 242
Cdd:COG1116  141 GGMRQRVAIARALANDPEVLLMDEPFGALDAltreRLQDELLR----LWQETGKTVLFVTHD---VDEavfLADRVVVL 212
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 336-552 3.10e-43

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 154.65  E-value: 3.10e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIE-----PTSGDVMLDGYEVLKLDKTTLRtMRRSVQMIFQ- 409
Cdd:cd03260   11 GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDlipgaPDEGEVLLDGKDIYDLDVDVLE-LRRRVGMVFQk 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 410 -DPFasldpRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSPDMMRR-FPHEFSGGQRQRIAIARSLMLDPKVIV 487
Cdd:cd03260   90 pNPF-----PGSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDEVKDRlHALGLSGGQQQRLCLARALANEPEVLL 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 488 ADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAV 552
Cdd:cd03260  165 LDEPTSALDPISTAKI--EELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 312-568 3.37e-43

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 155.47  E-value: 3.37e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLK 391
Cdd:PRK11701   4 QPLLSVRGLTKLY-----------GPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 392 LDKTTL------RTMRRSVQMIFQDPFASLDPRMSVGTAIMEPFIEhrLGTKQ--QAREKAADLLEKVGLSPDMMRRFPH 463
Cdd:PRK11701  73 RDLYALseaerrRLLRTEWGFVHQHPRDGLRMQVSAGGNIGERLMA--VGARHygDIRATAGDWLERVEIDAARIDDLPT 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 464 EFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEI 543
Cdd:PRK11701 151 TFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRV 230

                        250       260
                 ....*....|....*....|....*
gi 549799341 544 VEIGPRAAVFDNPQHPYTKKLMSAV 568
Cdd:PRK11701 231 VESGLTDQVLDDPQHPYTQLLVSSV 255
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 16-259 3.94e-43

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 158.34  E-value: 3.94e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTslsiMRL---LDKKTSrieGKVMLGGRDLLA 92
Cdd:COG3842    3 MPALELENVSKRY----GDVTALDDVSLSIEPGEFVALLGPSGCGKTTL----LRMiagFETPDS---GRILLDGRDVTG 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  93 LPEEEmrkvRgkDISMIFQEPmtslnPIFP---IGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQF 169
Cdd:COG3842   72 LPPEK----R--NVGMVFQDY-----ALFPhltVAENVAFGLRM-RGVPKAEIRARVAELLELVGLEGLADR---YPHQL 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVE 249
Cdd:COG3842  137 SGGQQQRVALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQ 216

                        250
                 ....*....|
gi 549799341 250 TGTTDDIFHR 259
Cdd:COG3842  217 VGTPEEIYER 226
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
315-543 4.58e-43

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 153.43  E-value: 4.58e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFDIRSGLfgrksgavhavEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDK 394
Cdd:COG4619    1 LELEGLSFRVGGKPIL-----------SPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPP 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 TTLRtmrRSVQMIFQDPFAsldPRMSVGTAIMEPFiehRLGTKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIA 474
Cdd:COG4619   70 PEWR---RQVAYVPQEPAL---WGGTVRDNLPFPF---QLRERKFDRERALELLERLGLPPDILDKPVERLSGGERQRLA 140

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 475 IARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEI 543
Cdd:COG4619  141 LIRALLLQPDVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 19-256 7.05e-43

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 153.49  E-value: 7.05e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDK-KTSRIEGKVMLGGRDLLALPE-- 95
Cdd:cd03260    1 IELRDLNVYY----GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLiPGAPDEGEVLLDGKDIYDLDVdv 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGkdisMIFQEPmtslNPiFP--IGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIP-NAKNRFDdyPHQFSGG 172
Cdd:cd03260   77 LELRRRVG----MVFQKP----NP-FPgsIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWdEVKDRLH--ALGLSGG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 173 MRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEegMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGT 252
Cdd:cd03260  146 QQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGP 223


                 ....
gi 549799341 253 TDDI 256
Cdd:cd03260  224 TEQI 227
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 310-538 9.91e-43

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 154.48  E-value: 9.91e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 310 GRTPILSVKDLTTRFdirsglfGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEV 389
Cdd:COG1116    3 AAAPALELRGVSKRF-------PTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 390 LKLDKttlrtmRRSvqMIFQDPfaSLDPRMSVGTAIMEPFiEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQ 469
Cdd:COG1116   76 TGPGP------DRG--VVFQEP--ALLPWLTVLDNVALGL-ELRGVPKAERRERARELLELVGLA-GFEDAYPHQLSGGM 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341 470 RQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDM--AVveRVSHRVAVM 538
Cdd:COG1116  144 RQRVAIARALANDPEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVdeAV--FLADRVVVL 212
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
19-256 1.82e-42

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 152.91  E-value: 1.82e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdKKTSrieGKVMLGGRDLLALPEEEM 98
Cdd:COG1131    1 IEVRGLTKRY----GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLL-RPTS---GEVRVLGEDVARDPAEVR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKvrgkdISMIFQEPmtSLNPIFPIgkqiAEALTVHQD---ISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQ 175
Cdd:COG1131   73 RR-----IGYVPQEP--ALYPDLTV----RENLRFFARlygLPRKEARERIDELLELFGLTDAADR---KVGTLSGGMKQ 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDD 255
Cdd:COG1131  139 RLGLALALLHDPELLILDEPTSGLDPEARRELWELLRELA-AEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDE 217


                 .
gi 549799341 256 I 256
Cdd:COG1131  218 L 218
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 329-552 1.89e-42

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 153.11  E-value: 1.89e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 329 GLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIF 408
Cdd:cd03256    5 NLSKTYPNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQLRRQIGMIF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 409 QDPfaSLDPRMSVGTAIMEPfiehRLGTK-----------QQAREKAADLLEKVGLSPDMMRRfPHEFSGGQRQRIAIAR 477
Cdd:cd03256   85 QQF--NLIERLSVLENVLSG----RLGRRstwrslfglfpKEEKQRALAALERVGLLDKAYQR-ADQLSGGQQQRVAIAR 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 478 SLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAV 552
Cdd:cd03256  158 ALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
15-271 3.03e-42

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 153.41  E-value: 3.03e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  15 VSPVLSVQNLTTSFRVDGGW-----KSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRD 89
Cdd:PRK15112   1 VETLLEVRNLSKTFRYRTGWfrrqtVEAVKPLSFTLREGQTLAIIGENGSGKS----TLAKMLAGMIEPTSGELLIDDHP 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  90 LlalpEEEMRKVRGKDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRI-PNAKNRfddYPHQ 168
Cdd:PRK15112  77 L----HFGDYSYRSQRIRMIFQDPSTSLNPRQRISQILDFPLRLNTDLEPEQREKQIIETLRQVGLlPDHASY---YPHM 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:PRK15112 150 LAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVV 229

                        250       260
                 ....*....|....*....|...
gi 549799341 249 ETGTTDDIFHRGRHPYTRALLSA 271
Cdd:PRK15112 230 ERGSTADVLASPLHELTKRLIAG 252
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 315-562 5.03e-42

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 151.50  E-value: 5.03e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFDirsglfgrkSGAVHavEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDK 394
Cdd:cd03261    1 IELRGLTKSFG---------GRTVL--KGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSE 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 TTLRTMRRSVQMIFQDP--FASldprMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSPDmMRRFPHEFSGGQRQR 472
Cdd:cd03261   70 AELYRLRRRMGMLFQSGalFDS----LTVFENVAFPLREHTRLSEEEIREIVLEKLEAVGLRGA-EDLYPAELSGGMKKR 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 473 IAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAV 552
Cdd:cd03261  145 VALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224

                        250
                 ....*....|
gi 549799341 553 FDNpQHPYTK 562
Cdd:cd03261  225 RAS-DDPLVR 233
LolD_lipo_ex TIGR02211
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...
 18-249 5.07e-42

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 131266 [Multi-domain]  Cd Length: 221  Bit Score: 150.96  E-value: 5.07e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   18 VLSVQNLTTSFRvDGGWKS-VVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEE 96
Cdd:TIGR02211   1 LLKCENLGKRYQ-EGKLDTrVLKGVSLSIGKGEIVAIVGSSGSGKS-TLLHLLGGLDNPTS---GEVLFNGQSLSKLSSN 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   97 EMRKVRGKDISMIFQepMTSLNPIFPIGKQIA-EALTVHQDISSSAAKAEviRLLEKVripNAKNRFDDYPHQFSGGMRQ 175
Cdd:TIGR02211  76 ERAKLRNKKLGFIYQ--FHHLLPDFTALENVAmPLLIGKKSVKEAKERAY--EMLEKV---GLEHRINHRPSELSGGERQ 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341  176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGvVAEVSDRTIVMFRGDVVE 249
Cdd:TIGR02211 149 RVAIARALVNQPSLVLADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLE-LAKKLDRVLEMKDGQLFN 221
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 19-251 5.07e-42

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 150.75  E-value: 5.07e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEm 98
Cdd:cd03259    1 LELKGLSKTY----GSVRALDDLSLTVEPGEFLALLGPSGCGKT----TLLRLIAGLERPDSGEILIDGRDVTGVPPER- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 rkvrgKDISMIFQEPmtSLNPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVM 178
Cdd:cd03259   72 -----RNIGMVFQDY--ALFPHLTVAENIAFGLKL-RGVPKAEIRARVRELLELVGLEGLLNR---YPHELSGGQQQRVA 140

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:cd03259  141 LARALAREPSLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 19-245 6.42e-42

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 150.37  E-value: 6.42e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLAlPEEEM 98
Cdd:cd03262    1 IEIKNLHKSF----GDFHVLKGIDLTVKKGEVVVIIGPSGSGKS-TLLRCINLLEEPDS---GTIIIDGLKLTD-DKKNI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRgKDISMIFQepmtSLNpIFP---IGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNaknRFDDYPHQFSGGMRQ 175
Cdd:cd03262   72 NELR-QKVGMVFQ----QFN-LFPhltVLENITLAPIKVKGMSKAEAEERALELLEKVGLAD---KADAYPAQLSGGQQQ 142

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:cd03262  143 RVAIARALAMNPKVMLFDEPTSALDPELVGEVLDVMKDLA-EEGMTMVVVTHEMGFAREVADRVIFMDDG 211
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 315-543 1.11e-41

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 149.99  E-value: 1.11e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyEVLKLDK 394
Cdd:cd03262    1 IEIKNLHKSF-----------GDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDG-LKLTDDK 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 TTLRTMRRSVQMIFQDpFaSLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIA 474
Cdd:cd03262   69 KNINELRQKVGMVFQQ-F-NLFPHLTVLENITLAPIKVKGMSKAEAEERALELLEKVGLA-DKADAYPAQLSGGQQQRVA 145

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 475 IARSLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEI 543
Cdd:cd03262  146 IARALAMNPKVMLFDEPTSALDPELVGEV-LDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 315-568 1.82e-41

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 153.38  E-value: 1.82e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyEVLKldk 394
Cdd:COG1118    3 IEVRNISKRF-----------GSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNG-RDLF--- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 TTLRTMRRSVQMIFQDpFAsLDPRMSVGTAIMepF-IEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRI 473
Cdd:COG1118   68 TNLPPRERRVGFVFQH-YA-LFPHMTVAENIA--FgLRVRPPSKAEIRARVEELLELVQLE-GLADRYPSQLSGGQRQRV 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 474 AIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVF 553
Cdd:COG1118  143 ALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVY 222

                        250
                 ....*....|....*
gi 549799341 554 DNPQHPYTKKLMSAV 568
Cdd:COG1118  223 DRPATPFVARFLGCV 237
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 8-270 2.40e-41

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 150.57  E-value: 2.40e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   8 MEQTGGSVSPVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSL-SIMRLLDK-KTSRIEGKVML 85
Cdd:COG1117    1 MTAPASTLEPKIEVRNLNVYY----GDKQALKDINLDIPENKVTALIGPSGCGKS-TLLrCLNRMNDLiPGARVEGEILL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  86 GGRDLLAlPEEEMRKVRgKDISMIFQEPmtslNPiFP--IGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPN-AKNRF 162
Cdd:COG1117   76 DGEDIYD-PDVDVVELR-RRVGMVFQKP----NP-FPksIYDNVAYGLRLHGIKSKSELDEIVEESLRKAALWDeVKDRL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 163 DDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEegMSVLFITHDMGVVAEVSDRTIVM 242
Cdd:COG1117  149 KKSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKD--YTIVIVTHNMQQAARVSDYTAFF 226

                        250       260
                 ....*....|....*....|....*...
gi 549799341 243 FRGDVVETGTTDDIFHRGRHPYTRALLS 270
Cdd:COG1117  227 YLGELVEFGPTEQIFTNPKDKRTEDYIT 254
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
17-552 3.52e-41

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 156.33  E-value: 3.52e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFrvdGGWKsVVRNMSFEIAPRETVAIVGESGSGKSvTslsIMRLL------DkktsriEGKVMLGGRDL 90
Cdd:COG1129    3 PLLEMRGISKSF---GGVK-ALDGVSLELRPGEVHALLGENGAGKS-T---LMKILsgvyqpD------SGEILLDGEPV 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  91 -LALPEEEMRkvRGkdISMIFQEPmtSLNP-------IFpIGKQIAEALTVHQdissSAAKAEVIRLLEKVRI---PNAK 159
Cdd:COG1129   69 rFRSPRDAQA--AG--IAIIHQEL--NLVPnlsvaenIF-LGREPRRGGLIDW----RAMRRRARELLARLGLdidPDTP 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 160 NRfddyphQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRT 239
Cdd:COG1129  138 VG------DLSVAQQQLVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRLK-AQGVAIIYISHRLDEVFEIADRV 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 240 IVMFRGDVVETGTTDDIfhrgrhpyTRALLSAvpklgSMKERLLPARFPIIDIKTGEsqpvadvkdtvsggrtPILSVKD 319
Cdd:COG1129  211 TVLRDGRLVGTGPVAEL--------TEDELVR-----LMVGRELEDLFPKRAAAPGE----------------VVLEVEG 261

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 320 LTTRfdirsglfgrksgavHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldktTLRT 399
Cdd:COG1129  262 LSVG---------------GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPV------RIRS 320

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 400 MRRSVQM-------------IFQDpfasldprMSVGT----AIMEPFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRFP 462
Cdd:COG1129  321 PRDAIRAgiayvpedrkgegLVLD--------LSIREnitlASLDRLSRGGLLDRRRERALAEEYIKRLRIKTPSPEQPV 392

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 463 HEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQV-----------CnllldlqqnlnlAFLFISHDMAVVERV 531
Cdd:COG1129  393 GNLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIyrlirelaaegK------------AVIVISSELPELLGL 460

                        570       580
                 ....*....|....*....|.
gi 549799341 532 SHRVAVMYLGEIVEIGPRAAV 552
Cdd:COG1129  461 SDRILVMREGRIVGELDREEA 481
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 19-263 1.05e-40

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 148.22  E-value: 1.05e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTslsiMRLLDKKTSRIEGKVMLGGRDLLALPEEEM 98
Cdd:cd03295    1 IEFENVTKRY---GGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTT----MKMINRLIEPTSGEIFIDGEDIREQDPVEL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKvrgkDISMIFQEpmTSLNPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRfDDYPHQFSGGMRQRVM 178
Cdd:cd03295   74 RR----KIGYVIQQ--IGLFPHMTVEENIALVPKL-LKWPKEKIRERADELLALVGLDPAEFA-DRYPHELSGGQQQRVG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFh 258
Cdd:cd03295  146 VARALAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEIL- 224


                 ....*
gi 549799341 259 rgRHP 263
Cdd:cd03295  225 --RSP 227
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 336-557 1.14e-40

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 147.86  E-value: 1.14e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyevLKLDKTTLRTMRRSVQMIFQDPFASL 415
Cdd:COG1122   12 GGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDG---KDITKKNLRELRRKVGLVFQNPDDQL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 dprmsVGTAIME-----PFiehRLG-TKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVAD 489
Cdd:COG1122   89 -----FAPTVEEdvafgPE---NLGlPREEIRERVEEALELVGLE-HLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLD 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 490 EAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQ 557
Cdd:COG1122  160 EPTAGLDPRGRREL-LELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDYE 226
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 17-552 1.30e-40

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 154.80  E-value: 1.30e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFrvdGGwksVV--RNMSFEIAPRETVAIVGESGSGKSvtslSIMRLL------DkktsriEGKVMLGGR 88
Cdd:COG3845    4 PALELRGITKRF---GG---VVanDDVSLTVRPGEIHALLGENGAGKS----TLMKILyglyqpD------SGEILIDGK 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  89 dllalpeeemrKVRGKD--------ISMIFQEPMtslnpifpigkqIAEALTVHQDI------------SSSAAKAEVIR 148
Cdd:COG3845   68 -----------PVRIRSprdaialgIGMVHQHFM------------LVPNLTVAENIvlgleptkggrlDRKAARARIRE 124

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 149 LLEKVRI---PNAKnrfddyPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALdvTIQgQILDLIKTLQE--EEGMSVL 223
Cdd:COG3845  125 LSERYGLdvdPDAK------VEDLSVGEQQRVEILKALYRGARILILDEPTAVL--TPQ-EADELFEILRRlaAEGKSII 195

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 224 FITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIfhrgrhpyTRALLSAvpklgSMkerllparfpiidikTGESQPVADV 303
Cdd:COG3845  196 FITHKLREVMAIADRVTVLRRGKVVGTVDTAET--------SEEELAE-----LM---------------VGREVLLRVE 247

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 304 KDTVSGGRtPILSVKDLTTrfdirsglfgRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVM 383
Cdd:COG3845  248 KAPAEPGE-VVLEVENLSV----------RDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIR 316

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 384 LDGYEVLKLDKTTLRtmRRSVQMIFQDPFAS-LDPRMSVGT-AIMEPFIEHRLGT-----KQQAREKAADLLEK---VGL 453
Cdd:COG3845  317 LDGEDITGLSPRERR--RLGVAYIPEDRLGRgLVPDMSVAEnLILGRYRRPPFSRggfldRKAIRAFAEELIEEfdvRTP 394

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 454 SPDMMRRFpheFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVS--------IKAQvcnllldlqQNLNLAFLFISHDM 525
Cdd:COG3845  395 GPDTPARS---LSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGaiefihqrLLEL---------RDAGAAVLLISEDL 462

                        570       580
                 ....*....|....*....|....*..
gi 549799341 526 AVVERVSHRVAVMYLGEIVEIGPRAAV 552
Cdd:COG3845  463 DEILALSDRIAVMYEGRIVGEVPAAEA 489
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 336-557 2.35e-40

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 147.00  E-value: 2.35e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDkttlrTMRRSVQMIFQDpFAsL 415
Cdd:cd03300   11 GGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLP-----PHKRPVNTVFQN-YA-L 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAIMEPFIEHRLGtKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSAL 495
Cdd:cd03300   84 FPHLTVFENIAFGLRLKKLP-KAEIKERVAEALDLVQLE-GYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGAL 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341 496 DVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQ 557
Cdd:cd03300  162 DLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPA 223
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
315-552 1.84e-39

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 144.44  E-value: 1.84e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDk 394
Cdd:COG1131    1 IEVRGLTKRY-----------GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDP- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 ttlRTMRRSVQMIFQDPfaSLDPRMSVGtAIMEPFIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIA 474
Cdd:COG1131   69 ---AEVRRRIGYVPQEP--ALYPDLTVR-ENLRFFARLYGLPRKEARERIDELLELFGLT-DAADRKVGTLSGGMKQRLG 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 475 IARSLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAV 552
Cdd:COG1131  142 LALALLHDPELLILDEPTSGLDPEARREL-WELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDEL 218
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 19-266 1.45e-38

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 145.29  E-value: 1.45e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLA-LPeee 97
Cdd:COG1118    3 IEVRNISKRF----GSFTLLDDVSLEIASGELVALLGPSGSGKT-TLLRIIAGLETPDS---GRIVLNGRDLFTnLP--- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 mrkVRGKDISMIFQEPMtslnpIFP---IGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMR 174
Cdd:COG1118   72 ---PRERRVGFVFQHYA-----LFPhmtVAENIAFGLRV-RPPSKAEIRARVEELLELVQLEGLADR---YPSQLSGGQR 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 175 QRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTD 254
Cdd:COG1118  140 QRVALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPD 219

                        250
                 ....*....|..
gi 549799341 255 DIFhrgRHPYTR 266
Cdd:COG1118  220 EVY---DRPATP 228
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 17-256 1.54e-38

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 142.50  E-value: 1.54e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFrvdGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSL-SIMRLLDKKtsriEGKVMLGGRDLLALPE 95
Cdd:COG3638    1 PMLELRNLSKRY---PGGTPALDDVSLEIERGEFVALIGPSGAGKS-TLLrCLNGLVEPT----SGEILVDGQDVTALRG 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGkDISMIFQEP--------MT--------------SLNPIFPigkqiaealtvhqdissSAAKAEVIRLLEKV 153
Cdd:COG3638   73 RALRRLRR-RIGMIFQQFnlvprlsvLTnvlagrlgrtstwrSLLGLFP-----------------PEDRERALEALERV 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 154 RIPN-AKNRFDdyphQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVV 232
Cdd:COG3638  135 GLADkAYQRAD----QLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLA 210

                        250       260
                 ....*....|....*....|....
gi 549799341 233 AEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:COG3638  211 RRYADRIIGLRDGRVVFDGPPAEL 234
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 344-491 1.79e-38

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 138.93  E-value: 1.79e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEvlkLDKTTLRTMRRSVQMIFQDPFasLDPRMSVGT 423
Cdd:pfam00005   4 VSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQD---LTDDERKSLRKEIGYVFQDPQ--LFPRLTVRE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341  424 AIMEPFIEHRLgTKQQAREKAADLLEKVGLSPDM---MRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEA 491
Cdd:pfam00005  79 NLRLGLLLKGL-SKREKDARAEEALEKLGLGDLAdrpVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEP 148
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 38-275 2.23e-38

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 142.78  E-value: 2.23e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  38 VRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEMRKVRGKDISMIFQEpmTSL 117
Cdd:cd03294   40 VNDVSLDVREGEIFVIMGLSGSGKS----TLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELRRKKISMVFQS--FAL 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 118 NPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVripNAKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTT 197
Cdd:cd03294  114 LPHRTVLENVAFGLEV-QGVPRAEREERAAEALELV---GLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFS 189

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 198 ALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRGRHPYTRALLSAVPKL 275
Cdd:cd03294  190 ALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFFRGVDRA 267
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 20-251 3.95e-38

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 139.11  E-value: 3.95e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  20 SVQNLttSFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvTSL-SIMRLLdkktSRIEGKVMLGGRDLLALPEEEM 98
Cdd:cd03214    1 EVENL--SVGYGG--RTVLDDLSLSIEAGEIVGILGPNGAGKS-TLLkTLAGLL----KPSSGEILLDGKDLASLSPKEL 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGkdismifqepmtslnpifpigkqiaealTVHQdisssaakaevirLLEKVRIPNAKNRFDDyphQFSGGMRQRVM 178
Cdd:cd03214   72 ARKIA----------------------------YVPQ-------------ALELLGLAHLADRPFN---ELSGGERQRVL 107

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:cd03214  108 LARALAQEPPILLLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 19-260 5.45e-38

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 141.41  E-value: 5.45e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   19 LSVQNLttSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLLAlpEEEM 98
Cdd:TIGR04520   1 IEVENV--SFSYPESEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPT----SGKVTVDGLDTLD--EENL 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   99 RKVRGKdISMIFQEPMTslnpifpigkQIAeALTVHQDI---------SSSAAKAEVIRLLEKVRIPNAKNRfddYPHQF 169
Cdd:TIGR04520  73 WEIRKK-VGMVFQNPDN----------QFV-GATVEDDVafglenlgvPREEMRKRVDEALKLVGMEDFRDR---EPHLL 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEvSDRTIVMFRGDVVE 249
Cdd:TIGR04520 138 SGGQKQRVAIAGVLAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAVL-ADRVIVMNKGKIVA 216

                         250
                  ....*....|.
gi 549799341  250 TGTTDDIFHRG 260
Cdd:TIGR04520 217 EGTPREIFSQV 227
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 336-542 5.60e-38

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 138.47  E-value: 5.60e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTlRTMRRSVQMIFQDPfaSL 415
Cdd:cd03229   11 GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDEL-PPLRRRIGMVFQDF--AL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAIMEPFiehrlgtkqqarekaadllekvglspdmmrrfphefSGGQRQRIAIARSLMLDPKVIVADEAVSAL 495
Cdd:cd03229   88 FPHLTVLENIALGL------------------------------------SGGQQQRVALARALAMDPDVLLLDEPTSAL 131

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 549799341 496 DVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGE 542
Cdd:cd03229  132 DPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
313-569 7.43e-38

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 143.02  E-value: 7.43e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFDIrsglfgrKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEP----TSGDVMLDGYE 388
Cdd:PRK15093   2 PLLDIRNLTIEFKT-------SDGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDnwrvTADRMRFDDID 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 389 VLKLdktTLRTMRR----SVQMIFQDPFASLDPRMSVGTAIMEPFIE--------HRLGTKQQareKAADLLEKVGLS-- 454
Cdd:PRK15093  75 LLRL---SPRERRKlvghNVSMIFQEPQSCLDPSERVGRQLMQNIPGwtykgrwwQRFGWRKR---RAIELLHRVGIKdh 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 455 PDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHR 534
Cdd:PRK15093 149 KDAMRSFPYELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADK 228

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 549799341 535 VAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAVP 569
Cdd:PRK15093 229 INVLYCGQTVETAPSKELVTTPHHPYTQALIRAIP 263
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 313-568 9.14e-38

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 140.35  E-value: 9.14e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  313 PILSVKDLTTRFDIRSGLFgrksgavhaveKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKL 392
Cdd:TIGR02323   2 PLLQVSGLSKSYGGGKGCR-----------DVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSGAEL 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  393 DKTTL------RTMRRSVQMIFQDPFASLDPRMSVGTAIMEPFIEhrLGTKQ--QAREKAADLLEKVGLSPDMMRRFPHE 464
Cdd:TIGR02323  71 ELYQLseaerrRLMRTEWGFVHQNPRDGLRMRVSAGANIGERLMA--IGARHygNIRATAQDWLEEVEIDPTRIDDLPRA 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  465 FSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIV 544
Cdd:TIGR02323 149 FSGGMQQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVV 228

                         250       260
                  ....*....|....*....|....
gi 549799341  545 EIGPRAAVFDNPQHPYTKKLMSAV 568
Cdd:TIGR02323 229 ESGLTDQVLDDPQHPYTQLLVSSI 252
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
336-557 1.88e-37

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 139.38  E-value: 1.88e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEV---LKLDKTTLRTMRRSVQMIFQDpf 412
Cdd:COG4161   13 GSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFdfsQKPSEKAIRLLRQKVGMVFQQ-- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 413 ASLDPRMSVgtaiMEPFIE---HRLG-TKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVA 488
Cdd:COG4161   91 YNLWPHLTV----MENLIEapcKVLGlSKEQAREKAMKLLARLRLT-DKADRFPLHLSGGQQQRVAIARALMMEPQVLLF 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 489 DEAVSALDVSIKAQVCNLLLDLQQNLNLAfLFISHDMAVVERVSHRVAVMYLGEIVEIGpRAAVFDNPQ 557
Cdd:COG4161  166 DEPTAALDPEITAQVVEIIRELSQTGITQ-VIVTHEVEFARKVASQVVYMEKGRIIEQG-DASHFTQPQ 232
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 38-197 3.72e-37

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 135.08  E-value: 3.72e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   38 VRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEMRKVrgkdISMIFQEPmtSL 117
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKS----TLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKE----IGYVFQDP--QL 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  118 NPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPN-AKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPT 196
Cdd:pfam00005  71 FPRLTVRENLRLGLLL-KGLSKREKDARAEEALEKLGLGDlADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149


                  .
gi 549799341  197 T 197
Cdd:pfam00005 150 A 150
heterocyst_DevA TIGR02982
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ...
 18-242 7.28e-37

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.


Pssm-ID: 274374 [Multi-domain]  Cd Length: 220  Bit Score: 137.07  E-value: 7.28e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   18 VLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLdkkTSRIEGKVMLGGRDLLALPEEE 97
Cdd:TIGR02982   1 VISIRNLNHYYGHGSLRKQVLFDINLEINPGEIVILTGPSGSGKT-TLLTLIGGL---RSVQEGSLKVLGQELHGASKKQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   98 MRKVRgKDISMIFQEpmTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIpnaKNRFDDYPHQFSGGMRQRV 177
Cdd:TIGR02982  77 LVQLR-RRIGYIFQA--HNLLGFLTARQNVQMALELQPNLSYQEARERARAMLEAVGL---GDHLNYYPHNLSGGQKQRV 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341  178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVaEVSDRTIVM 242
Cdd:TIGR02982 151 AIARALVHHPKLVLADEPTAALDSKSGRDVVELMQKLAKEQGCTILMVTHDNRIL-DVADRILQM 214
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 19-245 1.22e-36

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 135.01  E-value: 1.22e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVtslsIMRLLDKKTSRIEGKVMLGGRDLLALpeEEM 98
Cdd:cd03229    1 LELKNVSKRY----GQKTVLNDVSLNIEAGEIVALLGPSGSGKST----LLRCIAGLEEPDSGSILIDGEDLTDL--EDE 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGKDISMIFQEPmtSLNPIFPIGKQIAEALtvhqdisssaakaevirllekvripnaknrfddyphqfSGGMRQRVM 178
Cdd:cd03229   71 LPPLRRRIGMVFQDF--ALFPHLTVLENIALGL--------------------------------------SGGQQQRVA 110

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:cd03229  111 LARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDG 177
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 18-265 1.71e-36

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 136.97  E-value: 1.71e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDK-----KTSRIEGKVMLGGRDLLA 92
Cdd:PRK14247   3 KIEIRDLKVSF----GQVEVLDGVNLEIPDNTITALMGPSGSGKS----TLLRVFNRlielyPEARVSGEVYLDGQDIFK 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  93 LPEEEMRKvrgkDISMIFQEPmtslNPI--FPIGKQIAEALTVHQDISSSAAKAEVIR-LLEKVRI-PNAKNRFDDYPHQ 168
Cdd:PRK14247  75 MDVIELRR----RVQMVFQIP----NPIpnLSIFENVALGLKLNRLVKSKKELQERVRwALEKAQLwDEVKDRLDAPAGK 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEegMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:PRK14247 147 LSGGQQQRLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD--MTIVLVTHFPQQAARISDYVAFLYKGQIV 224

                        250
                 ....*....|....*..
gi 549799341 249 ETGTTDDIFHRGRHPYT 265
Cdd:PRK14247 225 EWGPTREVFTNPRHELT 241
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 16-257 1.73e-36

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 136.76  E-value: 1.73e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTtsFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvtSL--SIMRLLdKKTSrieGKVMLGGRDLlal 93
Cdd:COG1121    4 MPAIELENLT--VSYGG--RPVLEDVSLTIPPGEFVAIVGPNGAGKS--TLlkAILGLL-PPTS---GTVRLFGKPP--- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  94 peeemrKVRGKDISMIFQepMTSLNPIFPIgkqiaealTVHQ-------------DISSSAAKAEVIRLLEKVRIPNAKN 160
Cdd:COG1121   71 ------RRARRRIGYVPQ--RAEVDWDFPI--------TVRDvvlmgrygrrglfRRPSRADREAVDEALERVGLEDLAD 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 161 RfddyphQF---SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSD 237
Cdd:COG1121  135 R------PIgelSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELR-REGKTILVVTHDLGAVREYFD 207

                        250       260
                 ....*....|....*....|
gi 549799341 238 RTIVMFRGdVVETGTTDDIF 257
Cdd:COG1121  208 RVLLLNRG-LVAHGPPEEVL 226
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
42-271 2.04e-36

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 136.04  E-value: 2.04e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  42 SFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEmRKVrgkdiSMIFQEpmtslNPIF 121
Cdd:COG3840   19 DLTIAAGERVAILGPSGAGKS-TLLNLIAGFLPPDS---GRILWNGQDLTALPPAE-RPV-----SMLFQE-----NNLF 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 122 PigkqiaeALTVHQDIS---------SSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVMIAMALASKPKLLIA 192
Cdd:COG3840   84 P-------HLTVAQNIGlglrpglklTAEQRAQVEQALERVGLAGLLDR---LPGQLSGGQRQRVALARCLVRKRPILLL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 193 DEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRGRHPYTRALLSA 271
Cdd:COG3840  154 DEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYLGI 232
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 331-538 4.14e-36

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 134.52  E-value: 4.14e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 331 FGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEvlkLDKTTLRTMRRSVQMIFQD 410
Cdd:cd03225    7 FSYPDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKD---LTKLSLKELRRKVGLVFQN 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 411 P----FASldprmSVGTAIMepF-IEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKV 485
Cdd:cd03225   84 PddqfFGP-----TVEEEVA--FgLENLGLPEEEIEERVEEALELVGLE-GLRDRSPFTLSGGQKQRVAIAGVLAMDPDI 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 549799341 486 IVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVM 538
Cdd:cd03225  156 LLLDEPTAGLDPAGRREL-LELLKKLKAEGKTIIIVTHDLDLLLELADRVIVL 207
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
27-249 4.38e-36

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 134.79  E-value: 4.38e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  27 SFRVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLdkktSRIE----GKVMLGGRDLLALPEEEMRKVR 102
Cdd:COG2884    8 SKRYPGG-REALSDVSLEIEKGEFVFLTGPSGAGKS----TLLKLL----YGEErptsGQVLVNGQDLSRLKRREIPYLR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 103 gKDISMIFQEpmtslnpiF------PIGKQIAEALTVHqDISSSAAKAEVIRLLEKVRIpnaKNRFDDYPHQFSGGMRQR 176
Cdd:COG2884   79 -RRIGVVFQD--------FrllpdrTVYENVALPLRVT-GKSRKEIRRRVREVLDLVGL---SDKAKALPHELSGGEQQR 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 177 VMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVE 249
Cdd:COG2884  146 VAIARALVNRPELLLADEPTGNLDPETSWEIMELLEEIN-RRGTTVLIATHDLELVDRMPKRVLELEDGRLVR 217
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 315-557 6.13e-36

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 134.87  E-value: 6.13e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKL-- 392
Cdd:cd03219    1 LEVRGLTKRF-----------GGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLpp 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 393 DKTTLRTMRRSvqmiFQDPfaSLDPRMSVGTAIM--------EPFIEHR-LGTKQQAREKAADLLEKVGLSpDMMRRFPH 463
Cdd:cd03219   70 HEIARLGIGRT----FQIP--RLFPELTVLENVMvaaqartgSGLLLARaRREEREARERAEELLERVGLA-DLADRPAG 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 464 EFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCnLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEI 543
Cdd:cd03219  143 ELSYGQQRRLEIARALATDPKLLLLDEPAAGLNPEETEELA-ELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRV 221

                        250
                 ....*....|....
gi 549799341 544 VEIGPRAAVFDNPQ 557
Cdd:cd03219  222 IAEGTPDEVRNNPR 235
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 19-259 1.06e-35

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 134.23  E-value: 1.06e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEM 98
Cdd:cd03256    1 IEVENLSKTY---PNGKKALKDVSLSINPGEFVALIGPSGAGKS----TLLRCLNGLVEPTSGSVLIDGTDINKLKGKAL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRgKDISMIFQEPmtslnpifpigkQIAEALTVHQDIS-----------------SSAAKAEVIRLLEKVRI-PNAKN 160
Cdd:cd03256   74 RQLR-RQIGMIFQQF------------NLIERLSVLENVLsgrlgrrstwrslfglfPKEEKQRALAALERVGLlDKAYQ 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 161 RFDdyphQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTI 240
Cdd:cd03256  141 RAD----QLSGGQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIV 216

                        250       260
                 ....*....|....*....|...
gi 549799341 241 VMFRGDVVETGT----TDDIFHR 259
Cdd:cd03256  217 GLKDGRIVFDGPpaelTDEVLDE 239
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 336-557 2.08e-35

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 133.60  E-value: 2.08e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEV---LKLDKTTLRTMRRSVQMIFQDpf 412
Cdd:PRK11124  13 GAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFdfsKTPSDKAIRELRRNVGMVFQQ-- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 413 ASLDPRMSVgtaiMEPFIE---HRLG-TKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVA 488
Cdd:PRK11124  91 YNLWPHLTV----QQNLIEapcRVLGlSKDQALARAEKLLERLRLK-PYADRFPLHLSGGQQQRVAIARALMMEPQVLLF 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 489 DEAVSALDVSIKAQVCNLLLDLQQNLNLAFLfISHDMAVVERVSHRVAVMYLGEIVEIGPrAAVFDNPQ 557
Cdd:PRK11124 166 DEPTAALDPEITAQIVSIIRELAETGITQVI-VTHEVEVARKTASRVVYMENGHIVEQGD-ASCFTQPQ 232
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 19-266 2.55e-35

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 133.13  E-value: 2.55e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEm 98
Cdd:cd03300    1 IELENVSKFY----GGFVALDGVSLDIKEGEFFTLLGPSGCGKT-TLLRLIAGFETPTS---GEILLDGKDITNLPPHK- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 rkvrgKDISMIFQEpmTSLNPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVM 178
Cdd:cd03300   72 -----RPVNTVFQN--YALFPHLTVFENIAFGLRL-KKLPKAEIKERVAEALDLVQLEGYANR---KPSQLSGGQQQRVA 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFh 258
Cdd:cd03300  141 IARALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIY- 219


                 ....*...
gi 549799341 259 rgRHPYTR 266
Cdd:cd03300  220 --EEPANR 225
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 315-560 3.20e-35

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 135.97  E-value: 3.20e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldk 394
Cdd:COG3839    4 LELENVSKSY-----------GGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDV----- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 TTLRTMRRSVQMIFQDpFAsLDPRMSVGTAIMEPFIEHRLgTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIA 474
Cdd:COG3839   68 TDLPPKDRNIAMVFQS-YA-LYPHMTVYENIAFPLKLRKV-PKAEIDRRVREAAELLGLE-DLLDRKPKQLSGGQRQRVA 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 475 IARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHD----MAvverVSHRVAVMYLGEIVEIGPRA 550
Cdd:COG3839  144 LGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDqveaMT----LADRIAVMNDGRIQQVGTPE 219

                        250
                 ....*....|
gi 549799341 551 AVFDNPQHPY 560
Cdd:COG3839  220 ELYDRPANLF 229
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
334-576 3.42e-35

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 137.47  E-value: 3.42e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 334 KSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRS-VQMIFQDpF 412
Cdd:PRK10070  37 KTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKkIAMVFQS-F 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 413 AsLDPRMSV--GTAIMepfIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:PRK10070 116 A-LMPHMTVldNTAFG---MELAGINAEERREKALDALRQVGLE-NYAHSYPDELSGGMRQRVGLARALAINPDILLMDE 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 491 AVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAVPV 570
Cdd:PRK10070 191 AFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDI 270

                        250
                 ....*....|..
gi 549799341 571 P------DPARR 576
Cdd:PRK10070 271 SqvfsakDIARR 282
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
336-551 4.68e-35

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 132.10  E-value: 4.68e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQDpFaSL 415
Cdd:COG2884   13 GGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPYLRRRIGVVFQD-F-RL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAIMEPFIEHRLgTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSAL 495
Cdd:COG2884   91 LPDRTVYENVALPLRVTGK-SRKEIRRRVREVLDLVGLS-DKAKALPHELSGGEQQRVAIARALVNRPELLLADEPTGNL 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 496 D-----------VSIKAQvcnllldlqqnlNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAA 551
Cdd:COG2884  169 DpetsweimellEEINRR------------GTTVLIATHDLELVDRMPKRVLELEDGRLVRDEARGV 223
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
336-559 4.81e-35

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 132.52  E-value: 4.81e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKlDKTTLRTMRRSVQMIFQDpFaSL 415
Cdd:PRK09493  12 GPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVND-PKVDERLIRQEAGMVFQQ-F-YL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSAL 495
Cdd:PRK09493  89 FPHLTALENVMFGPLRVRGASKEEAEKQARELLAKVGLA-ERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSAL 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 496 DVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHP 559
Cdd:PRK09493 168 DPELRHEV-LKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQ 230
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 315-547 8.17e-35

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 130.84  E-value: 8.17e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldk 394
Cdd:cd03301    1 VELENVTKRF-----------GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDV----- 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 TTLRTMRRSVQMIFQDpFAsLDPRMSVGTAIMEPfIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIA 474
Cdd:cd03301   65 TDLPPKDRDIAMVFQN-YA-LYPHMTVYDNIAFG-LKLRKVPKDEIDERVREVAELLQIE-HLLDRKPKQLSGGQRQRVA 140

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 475 IARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:cd03301  141 LGRAIVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 317-560 9.40e-35

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 131.69  E-value: 9.40e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 317 VKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDktt 396
Cdd:cd03296    5 VRNVSKRF-----------GDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVP--- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 397 lrTMRRSVQMIFQDpfASLDPRMSVGTAI-----MEPfiEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQ 471
Cdd:cd03296   71 --VQERNVGFVFQH--YALFRHMTVFDNVafglrVKP--RSERPPEAEIRAKVHELLKLVQLD-WLADRYPAQLSGGQRQ 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 472 RIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAA 551
Cdd:cd03296  144 RVALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDE 223


                 ....*....
gi 549799341 552 VFDNPQHPY 560
Cdd:cd03296  224 VYDHPASPF 232
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 313-562 1.07e-34

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 132.08  E-value: 1.07e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIE--P---TSGDVMLDGY 387
Cdd:COG1117   10 PKIEVRNLNVYY-----------GDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDliPgarVEGEILLDGE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 388 EVL--KLDKTTLRtmrRSVQMIFQ--DPFAsldprMSvgtaIME----PFIEHRLGTKQQAREKAADLLEKVGLSP---D 456
Cdd:COG1117   79 DIYdpDVDVVELR---RRVGMVFQkpNPFP-----KS----IYDnvayGLRLHGIKSKSELDEIVEESLRKAALWDevkD 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 457 MMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD-----------VSIKAQVCNllldlqqnlnlafLFISHDM 525
Cdd:COG1117  147 RLKKSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDpistakieeliLELKKDYTI-------------VIVTHNM 213

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 549799341 526 AVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTK 562
Cdd:COG1117  214 QQAARVSDYTAFFYLGELVEFGPTEQIFTNPKDKRTE 250
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 18-256 1.29e-34

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 131.52  E-value: 1.29e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPeee 97
Cdd:COG4555    1 MIEVENLSKKY----GKVPALKDVSFTAKDGEITGLLGPNGAGKT-TLLRMLAGLLKPDS---GSILIDGEDVRKEP--- 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 mRKVRgKDISMIFQEpmtslNPIFPI--GKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQ 175
Cdd:COG4555   70 -REAR-RQIGVLPDE-----RGLYDRltVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDR---RVGELSTGMKK 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMsVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDD 255
Cdd:COG4555  140 KVALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALKKEGKT-VLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDE 218


                 .
gi 549799341 256 I 256
Cdd:COG4555  219 L 219
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 19-259 1.57e-34

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 130.92  E-value: 1.57e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSfrvdggWKS-VVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdkktSRIEGKVMLGGRDLLALPEEE 97
Cdd:cd03299    1 LKVENLSKD------WKEfKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFI----KPDSGKILLNGKDITNLPPEK 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 mrkvrgKDISMIFQEpmTSLNPIFPIGKQIAEALTvHQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRV 177
Cdd:cd03299   71 ------RDISYVPQN--YALFPHMTVYKNIAYGLK-KRKVDKKEIERKVLEIAEMLGIDHLLNR---KPETLSGGEQQRV 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIF 257
Cdd:cd03299  139 AIARALVVNPKILLLDEPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVF 218


                 ..
gi 549799341 258 HR 259
Cdd:cd03299  219 KK 220
3a0106s01 TIGR00968
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
 21-270 2.12e-34

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]


Pssm-ID: 130041 [Multi-domain]  Cd Length: 237  Bit Score: 130.69  E-value: 2.12e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   21 VQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPeeemrk 100
Cdd:TIGR00968   3 IANISKRF----GSFQALDDVNLEVPTGSLVALLGPSGSGKS-TLLRIIAGLEQPDS---GRIRLNGQDATRVH------ 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  101 VRGKDISMIFQEpmTSLNPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVMIA 180
Cdd:TIGR00968  69 ARDRKIGFVFQH--YALFKHLTVRDNIAFGLEI-RKHPKAKIKARVEELLELVQLEGLGDR---YPNQLSGGQRQRVALA 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  181 MALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFhrg 260
Cdd:TIGR00968 143 RALAVEPQVLLLDEPFGALDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVY--- 219

                         250
                  ....*....|
gi 549799341  261 RHPYTRALLS 270
Cdd:TIGR00968 220 DHPANPFVMS 229
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 341-567 2.61e-34

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 130.98  E-value: 2.61e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEP----TSGDVMLDGYEVLKldkTTLRTmrRSVQMIFQDPFASLD 416
Cdd:PRK10418  19 VHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAgvrqTAGRVLLDGKPVAP---CALRG--RKIATIMQNPRSAFN 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 417 PRMSVGTAIMEPFiehRLGTKQQAREKAADLLEKVGLS--PDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:PRK10418  94 PLHTMHTHARETC---LALGKPADDATLTAALEAVGLEnaARVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTD 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 495 LDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSA 567
Cdd:PRK10418 171 LDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTRSLVSA 243
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
16-260 2.95e-34

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 131.29  E-value: 2.95e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLttSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRdllALPE 95
Cdd:PRK13635   3 EEIIRVEHI--SFRYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKS----TLAKLLNGLLLPEAGTITVGGM---VLSE 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRgKDISMIFQEPmtslnpifpiGKQIAEAlTVHQDIS-----SSAAKAEVI-RLLEKVRIPNAKNRFDDYPHQF 169
Cdd:PRK13635  74 ETVWDVR-RQVGMVFQNP----------DNQFVGA-TVQDDVAfglenIGVPREEMVeRVDQALRQVGMEDFLNREPHRL 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEvSDRTIVMFRGDVVE 249
Cdd:PRK13635 142 SGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILE 220

                        250
                 ....*....|.
gi 549799341 250 TGTTDDIFHRG 260
Cdd:PRK13635 221 EGTPEEIFKSG 231
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 16-256 3.51e-34

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 130.54  E-value: 3.51e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFrvdGGWKsVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLdkkTSRI---EGKVMLGGRDLLA 92
Cdd:COG0411    2 DPLLEVRGLTKRF---GGLV-AVDDVSLEVERGEIVGLIGPNGAGKT----TLFNLI---TGFYrptSGRILFDGRDITG 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  93 LPEEEMRKvRGkdISMIFQEP-----MT----------------SLNPIFPIGKQIAEaltvhqdisSSAAKAEVIRLLE 151
Cdd:COG0411   71 LPPHRIAR-LG--IARTFQNPrlfpeLTvlenvlvaaharlgrgLLAALLRLPRARRE---------EREARERAEELLE 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 152 KVRIpnaKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGV 231
Cdd:COG0411  139 RVGL---ADRADEPAGNLSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDL 215

                        250       260
                 ....*....|....*....|....*
gi 549799341 232 VAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:COG0411  216 VMGLADRIVVLDFGRVIAEGTPAEV 240
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 315-552 5.91e-34

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 129.59  E-value: 5.91e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDK 394
Cdd:COG4555    2 IEVENLSKKY-----------GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPR 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 TTlrtmRRSVQMIFQDPFasLDPRMSVgTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRFpHEFSGGQRQRIA 474
Cdd:COG4555   71 EA----RRQIGVLPDERG--LYDRLTV-RENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRV-GELSTGMKKKVA 142

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 475 IARSLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAV 552
Cdd:COG4555  143 LARALVHDPKVLLLDEPTNGLDVMARRLL-REILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDEL 219
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 19-256 6.18e-34

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 129.09  E-value: 6.18e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdGGWKsVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEm 98
Cdd:cd03219    1 LEVRGLTKRF---GGLV-ALDDVSFSVRPGEIHGLIGPNGAGKT----TLFNLISGFLRPTSGSVLFDGEDITGLPPHE- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGkdISMIFQepmtslNP-IFP---------IGKQIAEALTVHQDISS---SAAKAEVIRLLEKVRIPNaknRFDDY 165
Cdd:cd03219   72 IARLG--IGRTFQ------IPrLFPeltvlenvmVAAQARTGSGLLLARARreeREARERAEELLERVGLAD---LADRP 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 166 PHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEeGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:cd03219  141 AGELSYGQQRRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIRELRER-GITVLLVEHDMDVVMSLADRVTVLDQG 219

                        250
                 ....*....|.
gi 549799341 246 DVVETGTTDDI 256
Cdd:cd03219  220 RVIAEGTPDEV 230
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 19-245 6.83e-34

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 127.13  E-value: 6.83e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDllalPEEEM 98
Cdd:cd03230    1 IEVRNLSKRY----GKKTALDDISLTVEKGEIYGLLGPNGAGKT-TLIKIILGLLKPDS---GEIKVLGKD----IKKEP 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGKdISMIFQEPMtslnpiFPigkqiaEALTVHQDIsssaakaevirllekvripnaknrfddyphQFSGGMRQRVM 178
Cdd:cd03230   69 EEVKRR-IGYLPEEPS------LY------ENLTVRENL------------------------------KLSGGMKQRLA 105

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:cd03230  106 LAQALLHDPELLILDEPTSGLDPESRREFWELLRELK-KEGKTILLSSHILEEAERLCDRVAILNNG 171
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
312-570 9.56e-34

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 132.65  E-value: 9.56e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFDirsglfgrksgAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyevlk 391
Cdd:PRK11607  17 TPLLEIRNLTKSFD-----------GQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDG----- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 392 LDKTTLRTMRRSVQMIFQDpfASLDPRMSVGTAIMEPFIEHRLgTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQ 471
Cdd:PRK11607  81 VDLSHVPPYQRPINMMFQS--YALFPHMTVEQNIAFGLKQDKL-PKAEIASRVNEMLGLVHMQ-EFAKRKPHQLSGGQRQ 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 472 RIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAA 551
Cdd:PRK11607 157 RVALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEE 236

                        250
                 ....*....|....*....
gi 549799341 552 VFDNPQHPYTKKLMSAVPV 570
Cdd:PRK11607 237 IYEHPTTRYSAEFIGSVNV 255
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 21-265 9.62e-34

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 129.00  E-value: 9.62e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  21 VQNLTTSFrvdGGWKSVvRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPeeemrk 100
Cdd:cd03296    5 VRNVSKRF---GDFVAL-DDVSLDIPSGELVALLGPSGSGKT-TLLRLIAGLERPDS---GTILFGGEDATDVP------ 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 101 VRGKDISMIFQEpmTSLNPIFPIGKQIAEALTV---HQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRV 177
Cdd:cd03296   71 VQERNVGFVFQH--YALFRHMTVFDNVAFGLRVkprSERPPEAEIRAKVHELLKLVQLDWLADR---YPAQLSGGQRQRV 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIF 257
Cdd:cd03296  146 ALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVY 225


                 ....*...
gi 549799341 258 hrgRHPYT 265
Cdd:cd03296  226 ---DHPAS 230
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
19-242 9.68e-34

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 127.62  E-value: 9.68e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLttSFRVDGGWksVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTsriEGKVMLGGRDLLALPEEEM 98
Cdd:COG4619    1 LELEGL--SFRVGGKP--ILSPVSLTLEAGECVAITGPSGSGKS-TLLRALADLDPPT---SGEIYLDGKPLSAMPPPEW 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKvrgkDISMIFQEPmtslnPIFP--IGKQIAEALTVHQDissSAAKAEVIRLLEKVRIPNAknrFDDYP-HQFSGGMRQ 175
Cdd:COG4619   73 RR----QVAYVPQEP-----ALWGgtVRDNLPFPFQLRER---KFDRERALELLERLGLPPD---ILDKPvERLSGGERQ 137

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVM 242
Cdd:COG4619  138 RLALIRALLLQPDVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTL 204
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 317-566 1.06e-33

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 129.10  E-value: 1.06e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 317 VKDLTTRFDIRSGLFGrksgavhavekVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSG-----DVMLDGYEVLK 391
Cdd:PRK11264   6 VKNLVKKFHGQTVLHG-----------IDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGtirvgDITIDTARSLS 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 392 LDKTTLRTMRRSVQMIFQDpfASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQ 471
Cdd:PRK11264  75 QQKGLIRQLRQHVGFVFQN--FNLFPHRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLA-GKETSYPRRLSGGQQQ 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 472 RIAIARSLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAA 551
Cdd:PRK11264 152 RVAIARALAMRPEVILFDEPTSALDPELVGEV-LNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKA 230

                        250
                 ....*....|....*
gi 549799341 552 VFDNPQHPYTKKLMS 566
Cdd:PRK11264 231 LFADPQQPRTRQFLE 245
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 18-264 1.09e-33

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 128.96  E-value: 1.09e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   18 VLSVQNLTTSFrvdGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEE 97
Cdd:TIGR02315   1 MLEVENLSKVY---PNGKQALKNINLNINPGEFVAIIGPSGAGKS----TLLRCINRLVEPSSGSILLEGTDITKLRGKK 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   98 MRKVRGKdISMIFQEpmtsLNPIfpigkqiaEALTVHQDI-----------------SSSAAKAEVIRLLEKVRIPN-AK 159
Cdd:TIGR02315  74 LRKLRRR-IGMIFQH----YNLI--------ERLTVLENVlhgrlgykptwrsllgrFSEEDKERALSALERVGLADkAY 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  160 NRFDdyphQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRT 239
Cdd:TIGR02315 141 QRAD----QLSGGQQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRI 216

                         250       260
                  ....*....|....*....|....*.
gi 549799341  240 IVMFRGDVVETGTTDDIF-HRGRHPY 264
Cdd:TIGR02315 217 VGLKAGEIVFDGAPSELDdEVLRHIY 242
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 16-266 3.45e-33

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 130.54  E-value: 3.45e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   16 SPVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPE 95
Cdd:TIGR03265   2 SPYLSIDNIRKRF----GAFTALKDISLSVKKGEFVCLLGPSGCGKT-TLLRIIAGLERQTA---GTIYQGGRDITRLPP 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   96 EEmrkvrgKDISMIFQEpmTSLNPIFPIGKQIAEALTvHQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQ 175
Cdd:TIGR03265  74 QK------RDYGIVFQS--YALFPNLTVADNIAYGLK-NRGMGRAEVAERVAELLDLVGLPGSERK---YPGQLSGGQQQ 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDD 255
Cdd:TIGR03265 142 RVALARALATSPGLLLLDEPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQE 221

                         250
                  ....*....|.
gi 549799341  256 IFhrgRHPYTR 266
Cdd:TIGR03265 222 IY---RHPATP 229
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
333-566 4.59e-33

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 127.39  E-value: 4.59e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 333 RKSGAVHAVEK-VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEV---------LKL-DKTTLRTMR 401
Cdd:PRK10619  12 HKRYGEHEVLKgVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTInlvrdkdgqLKVaDKNQLRLLR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 402 RSVQMIFQDpfASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLML 481
Cdd:PRK10619  92 TRLTMVFQH--FNLWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQRVSIARALAM 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 482 DPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYT 561
Cdd:PRK10619 170 EPEVLLFDEPTSALDPELVGEV-LRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQSPRL 248


                 ....*
gi 549799341 562 KKLMS 566
Cdd:PRK10619 249 QQFLK 253
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 315-547 4.77e-33

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 126.08  E-value: 4.77e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLkldk 394
Cdd:cd03263    1 LQIRNLTKTY---------KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIR---- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 TTLRTMRRSVQMIFQdpFASLDPRMSVgtaimepfIEH-----RL--GTKQQAREKAADLLEKVGLSPDMMRRfPHEFSG 467
Cdd:cd03263   68 TDRKAARQSLGYCPQ--FDALFDELTV--------REHlrfyaRLkgLPKSEIKEEVELLLRVLGLTDKANKR-ARTLSG 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 468 GQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCnlLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:cd03263  137 GMKRKLSLAIALIGGPSVLLLDEPTSGLDPASRRAIW--DLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIG 214
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
21-269 7.05e-33

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 129.43  E-value: 7.05e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  21 VQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEmRK 100
Cdd:PRK10851   5 IANIKKSF----GRTQVLNDISLDIPSGQMVALLGPSGSGKT-TLLRIIAGLEHQTS---GHIRFHGTDVSRLHARD-RK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 101 VrgkdiSMIFQE-----PMTSLNpifpigkQIAEALTV---HQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGG 172
Cdd:PRK10851  76 V-----GFVFQHyalfrHMTVFD-------NIAFGLTVlprRERPNAAAIKAKVTQLLEMVQLAHLADR---YPAQLSGG 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 173 MRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGT 252
Cdd:PRK10851 141 QKQRVALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGT 220

                        250
                 ....*....|....*..
gi 549799341 253 TDDIFhrgRHPYTRALL 269
Cdd:PRK10851 221 PDQVW---REPATRFVL 234
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
313-571 7.94e-33

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 127.44  E-value: 7.94e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFdirsglfgrKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyevLKL 392
Cdd:PRK13635   4 EIIRVEHISFRY---------PDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGG---MVL 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 393 DKTTLRTMRRSVQMIFQDPfaslDPRMsVGTAIMEPF---IEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQ 469
Cdd:PRK13635  72 SEETVWDVRRQVGMVFQNP----DNQF-VGATVQDDVafgLENIGVPREEMVERVDQALRQVGME-DFLNREPHRLSGGQ 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 470 RQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEIVEIGPR 549
Cdd:PRK13635 146 KQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTP 224

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 549799341 550 AAVFDNPQH--------PYTKKLMSA-----VPVP 571
Cdd:PRK13635 225 EEIFKSGHMlqeigldvPFSVKLKELlkrngILLP 259
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 20-245 9.37e-33

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 123.12  E-value: 9.37e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  20 SVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEMR 99
Cdd:cd00267    1 EIENLSFRY----GGRTALDNVSLTLKAGEIVALVGPNGSGKS----TLLRAIAGLLKPTSGEILIDGKDIAKLPLEELR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 100 KvrgkDISMIFQepmtslnpifpigkqiaealtvhqdisssaakaevirllekvripnaknrfddyphqFSGGMRQRVMI 179
Cdd:cd00267   73 R----RIGYVPQ---------------------------------------------------------LSGGQRQRVAL 91

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 180 AMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:cd00267   92 ARALLLNPDLLLLDEPTSGLDPASRERLLELLRELA-EEGRTVIIVTHDPELAELAADRVIVLKDG 156
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 20-251 1.77e-32

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 124.57  E-value: 1.77e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  20 SVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSL-SIMRLLdKKTSrieGKVMLGGRdllalPEEEM 98
Cdd:cd03235    1 EVEDLTVSY----GGHPVLEDVSFEVKPGEFLAIVGPNGAGKS-TLLkAILGLL-KPTS---GSIRVFGK-----PLEKE 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKvrgkDISMIFQEpmTSLNPIFPI-GKQIAE----ALTVHQDISSSAAKAEVIRLLEKVRIPNAKNR-FDdyphQFSGG 172
Cdd:cd03235   67 RK----RIGYVPQR--RSIDRDFPIsVRDVVLmglyGHKGLFRRLSKADKAKVDEALERVGLSELADRqIG----ELSGG 136

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 173 MRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRtIVMFRGDVVETG 251
Cdd:cd03235  137 QQQRVLLARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELR-REGMTILVVTHDLGLVLEYFDR-VLLLNRTVVASG 213
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 16-270 2.75e-32

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 131.43  E-value: 2.75e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLttSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLS-IMRLLDKKtsriEGKVMLGGRDLLALP 94
Cdd:COG4987  331 GPSLELEDV--SFRYPGAGRPVLDGLSLTLPPGERVAIVGPSGSGKS-TLLAlLLRFLDPQ----SGSITLGGVDLRDLD 403

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 EEEMRKVrgkdISMIFQEPmtslnPIFpiGKQIAEALTVHQDissSAAKAEVIRLLEKVRIpnaKNRFDDYPH------- 167
Cdd:COG4987  404 EDDLRRR----IAVVPQRP-----HLF--DTTLRENLRLARP---DATDEELWAALERVGL---GDWLAALPDgldtwlg 466

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 168 ----QFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeeEGMSVLFITHDMgVVAEVSDRTIVMF 243
Cdd:COG4987  467 eggrRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEAL--AGRTVLLITHRL-AGLERMDRILVLE 543

                        250       260
                 ....*....|....*....|....*..
gi 549799341 244 RGDVVETGTTDDIFHrgRHPYTRALLS 270
Cdd:COG4987  544 DGRIVEQGTHEELLA--QNGRYRQLYQ 568
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 19-264 3.68e-32

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 132.27  E-value: 3.68e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLttSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLdkktSRI----EGKVMLGGRDLLALP 94
Cdd:COG2274  474 IELENV--SFRYPGDSPPVLDNISLTIKPGERVAIVGRSGSGKS----TLLKLL----LGLyeptSGRILIDGIDLRQID 543

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 EEEMRKvrgkDISMIFQEPMtslnpIFPiGKqIAEALTVHQDissSAAKAEVIRLLEKVRIpnaknrfDDY----PH--- 167
Cdd:COG2274  544 PASLRR----QIGVVLQDVF-----LFS-GT-IRENITLGDP---DATDEEIIEAARLAGL-------HDFiealPMgyd 602

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 168 --------QFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLqeEEGMSVLFITHDMGVVAEVsDRT 239
Cdd:COG2274  603 tvvgeggsNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRL--LKGRTVIIIAHRLSTIRLA-DRI 679

                        250       260
                 ....*....|....*....|....*
gi 549799341 240 IVMFRGDVVETGTTDDIFHRGRHPY 264
Cdd:COG2274  680 IVLDKGRIVEDGTHEELLARKGLYA 704
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 40-254 5.68e-32

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 123.97  E-value: 5.68e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  40 NMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGR--DLLALP-EEEMRKVRgKDISMIFQEpmTS 116
Cdd:PRK11124  20 DITLDCPQGETLVLLGPSGAGKS-SLLRVLNLLEMPRS---GTLNIAGNhfDFSKTPsDKAIRELR-RNVGMVFQQ--YN 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 117 LNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFddyPHQFSGGMRQRVMIAMALASKPKLLIADEPT 196
Cdd:PRK11124  93 LWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRF---PLHLSGGQQQRVAIARALMMEPQVLLFDEPT 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 197 TALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTD 254
Cdd:PRK11124 170 AALDPEITAQIVSIIRELA-ETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDAS 226
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 341-557 7.12e-32

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 123.60  E-value: 7.12e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyevlkLDKTTLRTMRRSVQMIFQDpfASLDPRMS 420
Cdd:cd03299   15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNG-----KDITNLPPEKRDISYVPQN--YALFPHMT 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 421 VGTAImEPFIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIK 500
Cdd:cd03299   88 VYKNI-AYGLKKRKVDKKEIERKVLEIAEMLGID-HLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTK 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 501 AQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQ 557
Cdd:cd03299  166 EKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPK 222
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
22-256 8.28e-32

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 123.28  E-value: 8.28e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  22 QNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLAlPEEEMRKV 101
Cdd:PRK09493   5 KNVSKHF----GPTQVLHNIDLNIDQGEVVVIIGPSGSGKS-TLLRCINKLEEITS---GDLIVDGLKVND-PKVDERLI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 102 RgKDISMIFQE----P-MTSL-NPIF-PIgkQIAEAltvhqdiSSSAAKAEVIRLLEKVRIpnaKNRFDDYPHQFSGGMR 174
Cdd:PRK09493  76 R-QEAGMVFQQfylfPhLTALeNVMFgPL--RVRGA-------SKEEAEKQARELLAKVGL---AERAHHYPSELSGGQQ 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 175 QRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTD 254
Cdd:PRK09493 143 QRVAIARALAVKPKLMLFDEPTSALDPELRHEVLKVMQDLA-EEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQ 221


                 ..
gi 549799341 255 DI 256
Cdd:PRK09493 222 VL 223
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 21-270 1.14e-31

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 123.32  E-value: 1.14e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  21 VQNLTTSFRvdggWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTS-RIE-GKVMLGGRDLLALPEEEM 98
Cdd:PRK11264   6 VKNLVKKFH----GQTVLHGIDLEVKPGEVVAIIGPSGSGKT-TLLRCINLLEQPEAgTIRvGDITIDTARSLSQQKGLI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRgKDISMIFQepmtSLNpIFP---IGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKnrfDDYPHQFSGGMRQ 175
Cdd:PRK11264  81 RQLR-QHVGFVFQ----NFN-LFPhrtVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGKE---TSYPRRLSGGQQQ 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLfITHDMGVVAEVSDRTIVMFRGDVVETGTTDD 255
Cdd:PRK11264 152 RVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVI-VTHEMSFARDVADRAIFMDQGRIVEQGPAKA 230

                        250
                 ....*....|....*
gi 549799341 256 IFHRGRHPYTRALLS 270
Cdd:PRK11264 231 LFADPQQPRTRQFLE 245
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 21-240 1.29e-31

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 121.95  E-value: 1.29e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   21 VQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEMRK 100
Cdd:TIGR03608   1 LKNISKKF----GDKVILDDLNLTIEKGKMYAIIGESGSGKS-TLLNIIGLLEKFDS---GQVYLNGQETPPLNSKKASK 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  101 VRGKDISMIFQ-----EPMTslnpifpIGKQIAEALtVHQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQ 175
Cdd:TIGR03608  73 FRREKLGYLFQnfaliENET-------VEENLDLGL-KYKKLSKKEKREKKKEALEKVGLNLKLKQ---KIYELSGGEQQ 141

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341  176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMgVVAEVSDRTI 240
Cdd:TIGR03608 142 RVALARAILKPPPLILADEPTGSLDPKNRDEVLDLLLELN-DEGKTIIIVTHDP-EVAKQADRVI 204
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 336-566 1.47e-31

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 123.10  E-value: 1.47e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIE-----PTSGDVMLDGYEVLKLDKTTLRtmrRSVQMIFQD 410
Cdd:PRK14247  14 GQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIElypeaRVSGEVYLDGQDIFKMDVIELR---RRVQMVFQI 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 411 PfaSLDPRMSVGTAI-MEPFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRF---PHEFSGGQRQRIAIARSLMLDPKVI 486
Cdd:PRK14247  91 P--NPIPNLSIFENVaLGLKLNRLVKSKKELQERVRWALEKAQLWDEVKDRLdapAGKLSGGQQQRLCIARALAFQPEVL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 487 VADEAVSALDVSIKAQVcnllldlqqnlNLAFLFISHDMAVV---------ERVSHRVAVMYLGEIVEIGPRAAVFDNPQ 557
Cdd:PRK14247 169 LADEPTANLDPENTAKI-----------ESLFLELKKDMTIVlvthfpqqaARISDYVAFLYKGQIVEWGPTREVFTNPR 237


                 ....*....
gi 549799341 558 HPYTKKLMS 566
Cdd:PRK14247 238 HELTEKYVT 246
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 25-272 2.01e-31

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 122.64  E-value: 2.01e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  25 TTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLD-KKTSRIEGKVMLGGRDLLAlPEEEMRKVRg 103
Cdd:PRK14267   7 TVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLElNEEARVEGEVRLFGRNIYS-PDVDPIEVR- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 104 KDISMIFQEPmtslNPiFP---IGKQIAEALTVHQDISSSAAKAEVIR-LLEKVRI-PNAKNRFDDYPHQFSGGMRQRVM 178
Cdd:PRK14267  85 REVGMVFQYP----NP-FPhltIYDNVAIGVKLNGLVKSKKELDERVEwALKKAALwDEVKDRLNDYPSNLSGGQRQRLV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEegMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFH 258
Cdd:PRK14267 160 IARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKE--YTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFE 237

                        250
                 ....*....|....
gi 549799341 259 RGRHPYTRALLSAV 272
Cdd:PRK14267 238 NPEHELTEKYVTGA 251
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 331-552 4.21e-31

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 128.80  E-value: 4.21e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 331 FGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRtmrRSVQMIFQD 410
Cdd:COG2274  481 FRYPGDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASLR---RQIGVVLQD 557

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 411 P--FAsldprmsvGTaIMEPFiehRLGTKQQAREKAADLLEKVGLSPDMMRRfPH-----------EFSGGQRQRIAIAR 477
Cdd:COG2274  558 VflFS--------GT-IRENI---TLGDPDATDEEIIEAARLAGLHDFIEAL-PMgydtvvgeggsNLSGGQRQRLAIAR 624

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 478 SLMLDPKVIVADEAVSALDVSIKAQVCnlLLDLQQNLNLAFLFISHDMAVVERVsHRVAVMYLGEIVEIGPRAAV 552
Cdd:COG2274  625 ALLRNPRILILDEATSALDAETEAIIL--ENLRRLLKGRTVIIIAHRLSTIRLA-DRIIVLDKGRIVEDGTHEEL 696
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 314-568 4.42e-31

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 121.69  E-value: 4.42e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTtrfdirsglFGRKSGAVhaVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLd 393
Cdd:COG1120    1 MLEAENLS---------VGYGGRPV--LDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASL- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 ktTLRTMRRSVQMIFQDPFASLDprMSVGTAIM---EPFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRFpHEFSGGQR 470
Cdd:COG1120   69 --SRRELARRIAYVPQEPPAPFG--LTVRELVAlgrYPHLGLFGRPSAEDREAVEEALERTGLEHLADRPV-DELSGGER 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 471 QRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRA 550
Cdd:COG1120  144 QRVLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPE 223

                        250
                 ....*....|....*...
gi 549799341 551 AVFdnpqhpyTKKLMSAV 568
Cdd:COG1120  224 EVL-------TPELLEEV 234
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 19-245 4.47e-31

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 119.02  E-value: 4.47e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLttSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLLALPEEEM 98
Cdd:cd03228    1 IEFKNV--SFSYPGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPT----SGEILIDGVDLRDLDLESL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVrgkdISMIFQEPMtslnpIFpigkqiaeALTVHQDIsssaakaevirllekvripnaknrfddyphqFSGGMRQRVM 178
Cdd:cd03228   75 RKN----IAYVPQDPF-----LF--------SGTIRENI-------------------------------LSGGQRQRIA 106

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeeEGMSVLFITHDMGVVAEVsDRTIVMFRG 245
Cdd:cd03228  107 IARALLRDPPILILDEATSALDPETEALILEALRALA--KGKTVIVIAHRLSTIRDA-DRIIVLDDG 170
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
37-267 5.16e-31

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 121.27  E-value: 5.16e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  37 VVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGR--DLLALP-EEEMRKVRGKdISMIFQEp 113
Cdd:COG4161   17 ALFDINLECPSGETLVLLGPSGAGKS-SLLRVLNLLETPDS---GQLNIAGHqfDFSQKPsEKAIRLLRQK-VGMVFQQ- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 114 mTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFddyPHQFSGGMRQRVMIAMALASKPKLLIAD 193
Cdd:COG4161   91 -YNLWPHLTVMENLIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRF---PLHLSGGQQQRVAIARALMMEPQVLLFD 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 194 EPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTdDIFhrgRHPYTRA 267
Cdd:COG4161  167 EPTAALDPEITAQVVEIIRELS-QTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDA-SHF---TQPQTEA 235
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 19-259 8.57e-31

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 123.64  E-value: 8.57e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdGGwKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEm 98
Cdd:COG3839    4 LELENVSKSY---GG-VEALKDIDLDIEDGEFLVLLGPSGCGKS-TLLRMIAGLEDPTS---GEILIGGRDVTDLPPKD- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 rkvRgkDISMIFQEPMtslnpIFPigkqiaeALTVHQDISSS-----AAKAE----VIRLLEKVRIPNAKNRfddYPHQF 169
Cdd:COG3839   75 ---R--NIAMVFQSYA-----LYP-------HMTVYENIAFPlklrkVPKAEidrrVREAAELLGLEDLLDR---KPKQL 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHD------MGvvaevsDRTIVMF 243
Cdd:COG3839  135 SGGQRQRVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDqveamtLA------DRIAVMN 208

                        250
                 ....*....|....*.
gi 549799341 244 RGDVVETGTTDDIFHR 259
Cdd:COG3839  209 DGRIQQVGTPEELYDR 224
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 19-254 1.18e-30

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 119.53  E-value: 1.18e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFRvdGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLalpeEEM 98
Cdd:cd03263    1 LQIRNLTKTYK--KGTKPAVDDLSLNVYKGEIFGLLGHNGAGKT-TTLKMLTGELRPTS---GTAYINGYSIR----TDR 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRgKDISMIFQEpmtslNPIFPigkqiaeALTVHQ---------DISSSAAKAEVIRLLEKVRIPNAKNRFddyPHQF 169
Cdd:cd03263   71 KAAR-QSLGYCPQF-----DALFD-------ELTVREhlrfyarlkGLPKSEIKEEVELLLRVLGLTDKANKR---ARTL 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeeEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVE 249
Cdd:cd03263  135 SGGMKRKLSLAIALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVR--KGRSIILTTHSMDEAEALCDRIAIMSDGKLRC 212


                 ....*
gi 549799341 250 TGTTD 254
Cdd:cd03263  213 IGSPQ 217
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 21-256 1.47e-30

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 119.40  E-value: 1.47e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  21 VQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLalpeEEMRK 100
Cdd:cd03265    3 VENLVKKY----GDFEAVRGVSFRVRRGEIFGLLGPNGAGKT-TTIKMLTTLLKPTS---GRATVAGHDVV----REPRE 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 101 VRgKDISMIFQEPmtSLNPIFpigkQIAEALTVH---QDISSSAAKAEVIRLLEKVRIPNAKNRFDDYphqFSGGMRQRV 177
Cdd:cd03265   71 VR-RRIGIVFQDL--SVDDEL----TGWENLYIHarlYGVPGAERRERIDELLDFVGLLEAADRLVKT---YSGGMRRRL 140

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:cd03265  141 EIARSLVHRPEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 19-256 1.51e-30

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 119.08  E-value: 1.51e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLLALPEEEM 98
Cdd:cd03224    1 LEVENLNAGY----GKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPR----SGSIRFDGRDITGLPPHER 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKvRGkdISMIFQEPMtslnpIFPigkqiaeALTVHQDISSSA---AKAEVIRLLEKV--RIPNAKNRFDDYPHQFSGGM 173
Cdd:cd03224   73 AR-AG--IGYVPEGRR-----IFP-------ELTVEENLLLGAyarRRAKRKARLERVyeLFPRLKERRKQLAGTLSGGE 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 174 RQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTT 253
Cdd:cd03224  138 QQMLAIARALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELR-DEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTA 216


                 ...
gi 549799341 254 DDI 256
Cdd:cd03224  217 AEL 219
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 356-570 5.75e-30

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 120.68  E-value: 5.75e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  356 LVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldkTTLRTMRRSVQMIFQDpfASLDPRMSVGTAIMEPFIEHRLG 435
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDV-----TNVPPHLRHINMVFQS--YALFPHMTVEENVAFGLKMRKVP 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  436 tKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLN 515
Cdd:TIGR01187  74 -RAEIKPRVLEALRLVQLE-EFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLG 151

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 549799341  516 LAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAVPV 570
Cdd:TIGR01187 152 ITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINV 206
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 331-538 6.01e-30

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 115.94  E-value: 6.01e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 331 FGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLrtmRRSVQMIFQD 410
Cdd:cd03228    8 FSYPGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESL---RKNIAYVPQD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 411 PFasldpRMSvGTaIMEpfiehrlgtkqqarekaaDLLekvglspdmmrrfphefSGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:cd03228   85 PF-----LFS-GT-IRE------------------NIL-----------------SGGQRQRIAIARALLRDPPILILDE 122

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 549799341 491 AVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERVsHRVAVM 538
Cdd:cd03228  123 ATSALDPETEALI--LEALRALAKGKTVIVIAHRLSTIRDA-DRIIVL 167
cbiO PRK13637
energy-coupling factor transporter ATPase;
21-257 6.41e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 119.38  E-value: 6.41e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  21 VQNLT------TSFRvdggwKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdKKTSrieGKVMLGGRDLlALP 94
Cdd:PRK13637   5 IENLThiymegTPFE-----KKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLL-KPTS---GKIIIDGVDI-TDK 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 EEEMRKVRgKDISMIFQEPMTSLnpiF--PIGKQIAEALTvHQDISSSAAKAEVIRLLEKVRIPnaknrFDDY----PHQ 168
Cdd:PRK13637  75 KVKLSDIR-KKVGLVFQYPEYQL---FeeTIEKDIAFGPI-NLGLSEEEIENRVKRAMNIVGLD-----YEDYkdksPFE 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:PRK13637 145 LSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCE 224


                 ....*....
gi 549799341 249 ETGTTDDIF 257
Cdd:PRK13637 225 LQGTPREVF 233
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
10-266 7.52e-30

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 121.48  E-value: 7.52e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  10 QTGGSVSPVLSVQNLTTSFrvDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRD 89
Cdd:PRK11607  11 KTRKALTPLLEIRNLTKSF--DG--QHAVDDVSLTIYKGEIFALLGASGCGKS----TLLRMLAGFEQPTAGQIMLDGVD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  90 LLALPEEEmrkvrgKDISMIFQEpmTSLNPIFPIGKQIAEALTvhQD-ISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQ 168
Cdd:PRK11607  83 LSHVPPYQ------RPINMMFQS--YALFPHMTVEQNIAFGLK--QDkLPKAEIASRVNEMLGLVHMQEFAKR---KPHQ 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTI----QGQILDLIktlqEEEGMSVLFITHDMGVVAEVSDRTIVMFR 244
Cdd:PRK11607 150 LSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLrdrmQLEVVDIL----ERVGVTCVMVTHDQEEAMTMAGRIAIMNR 225

                        250       260
                 ....*....|....*....|..
gi 549799341 245 GDVVETGTTDDIFhrgRHPYTR 266
Cdd:PRK11607 226 GKFVQIGEPEEIY---EHPTTR 244
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
38-272 7.75e-30

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 121.68  E-value: 7.75e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  38 VRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEMRKVRGKDISMIFQEpmTSL 117
Cdd:PRK10070  44 VKDASLAIEEGEIFVIMGLSGSGKS----TMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIAMVFQS--FAL 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 118 NPIFPIGKQIAEALtvhqDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTT 197
Cdd:PRK10070 118 MPHMTVLDNTAFGM----ELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFS 193

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 198 ALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRGRHPYTRALLSAV 272
Cdd:PRK10070 194 ALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGV 268
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
312-552 8.24e-30

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 123.20  E-value: 8.24e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLK 391
Cdd:COG1129    2 EPLLEMRGISKSF-----------GGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRF 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 392 ldKTTLRTMRRSVQMIFQDPfaSLDPRMSVGTAIM---EP----FIEHRlgtkqQAREKAADLLEKVGL--SPDMMRRfp 462
Cdd:COG1129   71 --RSPRDAQAAGIAIIHQEL--NLVPNLSVAENIFlgrEPrrggLIDWR-----AMRRRARELLARLGLdiDPDTPVG-- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 463 hEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVS-----------IKAQvcnllldlqqnlNLAFLFISHDMAVVERV 531
Cdd:COG1129  140 -DLSVAQQQLVEIARALSRDARVLILDEPTASLTEReverlfriirrLKAQ------------GVAIIYISHRLDEVFEI 206

                        250       260
                 ....*....|....*....|.
gi 549799341 532 SHRVAVMYLGEIVEIGPRAAV 552
Cdd:COG1129  207 ADRVTVLRDGRLVGTGPVAEL 227
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 341-503 9.02e-30

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 116.81  E-value: 9.02e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEP---TSGDVMLDGYEVlkldkTTLRTMRRSVQMIFQDPFasLDP 417
Cdd:COG4136   17 LAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLLNGRRL-----TALPAEQRRIGILFQDDL--LFP 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 418 RMSVGTAImePF-IEHRLGtKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:COG4136   90 HLSVGENL--AFaLPPTIG-RAQRRARVEQALEEAGLA-GFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLD 165


                 ....*..
gi 549799341 497 VSIKAQV 503
Cdd:COG4136  166 AALRAQF 172
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 19-251 1.06e-29

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 116.59  E-value: 1.06e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTsLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEm 98
Cdd:cd03301    1 VELENVTKRF----GNVTALDDLNLDIADGEFVVLLGPSGCGKTTT-LRMIAGLEEPTS---GRIYIGGRDVTDLPPKD- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 rkvrgKDISMIFQEpmTSLNPIFPIGKQIAEALTVHqDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVM 178
Cdd:cd03301   72 -----RDIAMVFQN--YALYPHMTVYDNIAFGLKLR-KVPKDEIDERVREVAELLQIEHLLDR---KPKQLSGGQRQRVA 140

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:cd03301  141 LGRAIVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 315-543 1.10e-29

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 115.19  E-value: 1.10e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldK 394
Cdd:cd03230    1 IEVRNLSKRY-----------GKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDI----K 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 TTLRTMRRSVQMIFQDPfaSLDPRMSVgtaimepfiehrlgtkqqarekaADLLekvglspdmmrrfphEFSGGQRQRIA 474
Cdd:cd03230   66 KEPEEVKRRIGYLPEEP--SLYENLTV-----------------------RENL---------------KLSGGMKQRLA 105

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 475 IARSLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEI 543
Cdd:cd03230  106 LAQALLHDPELLILDEPTSGLDPESRREF-WELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
19-270 1.64e-29

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 119.82  E-value: 1.64e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRL---LDKKTsriEGKVMLGGRDLLAlpe 95
Cdd:PRK11432   7 VVLKNITKRF----GSNTVIDNLNLTIKQGTMVTLLGPSGCGKT----TVLRLvagLEKPT---EGQIFIDGEDVTH--- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 eemRKVRGKDISMIFQEpmTSLNPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRFDDyphQFSGGMRQ 175
Cdd:PRK11432  73 ---RSIQQRDICMVFQS--YALFPHMSLGENVGYGLKM-LGVPKEERKQRVKEALELVDLAGFEDRYVD---QISGGQQQ 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDD 255
Cdd:PRK11432 144 RVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQE 223

                        250
                 ....*....|....*
gi 549799341 256 IFhrgRHPYTRALLS 270
Cdd:PRK11432 224 LY---RQPASRFMAS 235
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 333-547 1.92e-29

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 115.93  E-value: 1.92e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 333 RKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKldktTLRTMRRSVQMIFQDPf 412
Cdd:cd03265    8 KKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVR----EPREVRRRIGIVFQDL- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 413 aSLDPRMSvGTAIMEpfIEHRL-GTK-QQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:cd03265   83 -SVDDELT-GWENLY--IHARLyGVPgAERRERIDELLDFVGLL-EAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDE 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 491 AVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:cd03265  158 PTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEG 214
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 14-265 1.93e-29

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 117.89  E-value: 1.93e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  14 SVSPVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTS-RIEGKVMLGGRDLLA 92
Cdd:PRK14271  17 AAAPAMAAVNLTLGF----AGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGyRYSGDVLLGGRSIFN 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  93 LPEE-EMRKvrgkDISMIFQEPmtslNPiFP--IGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNA-KNRFDDYPHQ 168
Cdd:PRK14271  93 YRDVlEFRR----RVGMLFQRP----NP-FPmsIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLWDAvKDRLSDSPFR 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEegMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:PRK14271 164 LSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRLV 241

                        250
                 ....*....|....*..
gi 549799341 249 ETGTTDDIFHRGRHPYT 265
Cdd:PRK14271 242 EEGPTEQLFSSPKHAET 258
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 16-265 3.30e-29

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 116.41  E-value: 3.30e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLD-KKTSRIEGKVMLGGRDLLAlP 94
Cdd:PRK14239   3 EPILQVSDLSVYY----NKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDlNPEVTITGSIVYNGHNIYS-P 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 EEEMRKVRgKDISMIFQEPmtslNPiFPIgkQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNA-----KNRFDDYPHQF 169
Cdd:PRK14239  78 RTDTVDLR-KEIGMVFQQP----NP-FPM--SIYENVVYGLRLKGIKDKQVLDEAVEKSLKGASiwdevKDRLHDSALGL 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMsvLFITHDMGVVAEVSDRTIVMFRGDVVE 249
Cdd:PRK14239 150 SGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDYTM--LLVTRSMQQASRISDRTGFFLDGDLIE 227

                        250
                 ....*....|....*.
gi 549799341 250 TGTTDDIFHRGRHPYT 265
Cdd:PRK14239 228 YNDTKQMFMNPKHKET 243
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 334-542 4.38e-29

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 113.11  E-value: 4.38e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 334 KSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDkttLRTMRRSVQMIFQdpfa 413
Cdd:cd00267    8 RYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLP---LEELRRRIGYVPQ---- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 414 sldprmsvgtaimepfiehrlgtkqqarekaadllekvglspdmmrrfpheFSGGQRQRIAIARSLMLDPKVIVADEAVS 493
Cdd:cd00267   81 ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTS 109

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 549799341 494 ALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGE 542
Cdd:cd00267  110 GLDPASRERL-LELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 16-257 5.07e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 116.24  E-value: 5.07e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLttSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdKKTSrieGKVMLGGrdlLALPE 95
Cdd:PRK13632   5 SVMIKVENV--SFSYPNSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLL-KPQS---GEIKIDG---ITISK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGKdISMIFQEPMTSLnpifpIGkqiaeaLTVHQDI---------SSSAAKAEVIRLLEKVRIpnaKNRFDDYP 166
Cdd:PRK13632  76 ENLKEIRKK-IGIIFQNPDNQF-----IG------ATVEDDIafglenkkvPPKKMKDIIDDLAKKVGM---EDYLDKEP 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 167 HQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGvvaEV--SDRTIVMFR 244
Cdd:PRK13632 141 QNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMD---EAilADKVIVFSE 217

                        250
                 ....*....|...
gi 549799341 245 GDVVETGTTDDIF 257
Cdd:PRK13632 218 GKLIAQGKPKEIL 230
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 2-260 5.48e-29

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 121.40  E-value: 5.48e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   2 LLAATSMEQTGGSVS------PVLSVQNLttSFRVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLS-IMRLLDK 74
Cdd:COG4988  314 LLDAPEPAAPAGTAPlpaagpPSIELEDV--SFSYPGG-RPALDGLSLTIPPGERVALVGPSGAGKS-TLLNlLLGFLPP 389

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  75 KtsriEGKVMLGGRDLLALPEEEMRKvrgkDISMIFQEPMtslnpIFPIgkQIAEALTVHQdisSSAAKAEVIRLLEKVR 154
Cdd:COG4988  390 Y----SGSILINGVDLSDLDPASWRR----QIAWVPQNPY-----LFAG--TIRENLRLGR---PDASDEELEAALEAAG 451

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 155 IpnakNRF-DDYPHQF-----------SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeeEGMSV 222
Cdd:COG4988  452 L----DEFvAALPDGLdtplgeggrglSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLA--KGRTV 525

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 549799341 223 LFITHDMGVVAEvSDRTIVMFRGDVVETGTTDDIFHRG 260
Cdd:COG4988  526 ILITHRLALLAQ-ADRILVLDDGRIVEQGTHEELLAKN 562
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 17-272 8.17e-29

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 115.25  E-value: 8.17e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLttSFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEE 96
Cdd:PRK13548   1 AMLEARNL--SVRLGG--RTLLDDVSLTLRPGEVVAILGPNGAGKS----TLLRALSGELSPDSGEVRLNGRPLADWSPA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  97 EMRKVRGkdisMIFQEpmTSLNPIFPIGKQIAEALTVHQdISSSAAKAEVIRLLEKVRIPNAKNRfdDYPhQFSGGMRQR 176
Cdd:PRK13548  73 ELARRRA----VLPQH--SSLSFPFTVEEVVAMGRAPHG-LSRAEDDALVAAALAQVDLAHLAGR--DYP-QLSGGEQQR 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 177 VMIAMALA------SKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVET 250
Cdd:PRK13548 143 VQLARVLAqlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVAD 222

                        250       260
                 ....*....|....*....|..
gi 549799341 251 GTTDDIFhrgrhpyTRALLSAV 272
Cdd:PRK13548 223 GTPAEVL-------TPETLRRV 237
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
345-559 1.06e-28

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 114.47  E-value: 1.06e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 345 SFDL--AEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldkTTLRTMRRSVQMIFQDP--FASLDPRMS 420
Cdd:COG3840   17 RFDLtiAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDL-----TALPPAERPVSMLFQENnlFPHLTVAQN 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 421 VGTAImepfieH---RLGTKQQARekAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:COG3840   92 IGLGL------RpglKLTAEQRAQ--VEQALERVGLA-GLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDP 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 498 SIKA-------QVCNLLLDLQqnlnlafLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHP 559
Cdd:COG3840  163 ALRQemldlvdELCRERGLTV-------LMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPP 224
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 38-256 2.05e-28

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 117.51  E-value: 2.05e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  38 VRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLdkktSR-IE---GKVMLGGRDLLALPEEEMRKVRGKDISMIFQE- 112
Cdd:COG4175   43 VNDASFDVEEGEIFVIMGLSGSGKS----TLVRCL----NRlIEptaGEVLIDGEDITKLSKKELRELRRKKMSMVFQHf 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 113 ---P-MTSL-NPIFPigkqiaeaLTVhQDISSSAAKAEVIRLLEKVripNAKNRFDDYPHQFSGGMRQRVMIAMALASKP 187
Cdd:COG4175  115 allPhRTVLeNVAFG--------LEI-QGVPKAERRERAREALELV---GLAGWEDSYPDELSGGMQQRVGLARALATDP 182

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 188 KLLIADEPTTALDVTI----QGQILDliktLQEEEGMSVLFITHD------MGvvaevsDRTIVMFRGDVVETGTTDDI 256
Cdd:COG4175  183 DILLMDEAFSALDPLIrremQDELLE----LQAKLKKTIVFITHDldealrLG------DRIAIMKDGRIVQIGTPEEI 251
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 336-568 2.34e-28

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 114.17  E-value: 2.34e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIE-----PTSGDVMLDGYEVLKLDKTTLRtMRRSVQMIFQ- 409
Cdd:PRK14267  15 GSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLElneeaRVEGEVRLFGRNIYSPDVDPIE-VRREVGMVFQy 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 410 -DPFASLDPRMSVGTAIMepfIEHRLGTKQQAREKAADLLEKVGL---SPDMMRRFPHEFSGGQRQRIAIARSLMLDPKV 485
Cdd:PRK14267  94 pNPFPHLTIYDNVAIGVK---LNGLVKSKKELDERVEWALKKAALwdeVKDRLNDYPSNLSGGQRQRLVIARALAMKPKI 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 486 IVADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLM 565
Cdd:PRK14267 171 LLMDEPTANIDPVGTAKI--EELLFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPEHELTEKYV 248


                 ...
gi 549799341 566 SAV 568
Cdd:PRK14267 249 TGA 251
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
 38-266 2.97e-28

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 115.18  E-value: 2.97e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   38 VRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPeeemRKVRgKDISMIFQEPmtSL 117
Cdd:TIGR01188   9 VDGVNFKVREGEVFGFLGPNGAGKT-TTIRMLTTLLRPTS---GTARVAGYDVVREP----RKVR-RSIGIVPQYA--SV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  118 NPIFPiGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVMIAMALASKPKLLIADEPTT 197
Cdd:TIGR01188  78 DEDLT-GRENLEMMGRLYGLPKDEAEERAEELLELFELGEAADR---PVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTT 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341  198 ALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHR--GRHPYTR 266
Cdd:TIGR01188 154 GLDPRTRRAIWDYIRALK-EEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRlgKDTLESR 223
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 340-557 4.14e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 113.93  E-value: 4.14e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlklDKTTLRTMRRSVQMIFQDP---F--AS 414
Cdd:PRK13632  24 ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITI---SKENLKEIRKKIGIIFQNPdnqFigAT 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 415 LDPRMSVGtaimepfIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:PRK13632 101 VEDDIAFG-------LENKKVPPKKMKDIIDDLAKKVGME-DYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSM 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 495 LDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEIVEIGPRAAVFDNPQ 557
Cdd:PRK13632 173 LDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAIL-ADKVIVFSEGKLIAQGKPKEILNNKE 234
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 40-259 4.25e-28

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 115.97  E-value: 4.25e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  40 NMSFEIAPRETVAIVGESGSGKSvtslSIMRL---LDKKTsriEGKVMLGGRDLL------ALPEEEMRkvrgkdISMIF 110
Cdd:COG4148   17 DVDFTLPGRGVTALFGPSGSGKT----TLLRAiagLERPD---SGRIRLGGEVLQdsargiFLPPHRRR------IGYVF 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 111 QEPmtSLnpiFPigkqiaeALTVHQDI----------SSSAAKAEVIRLLEkvrIPNAKNRfddYPHQFSGGMRQRVMIA 180
Cdd:COG4148   84 QEA--RL---FP-------HLSVRGNLlygrkrapraERRISFDEVVELLG---IGHLLDR---RPATLSGGERQRVAIG 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 181 MALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHR 259
Cdd:COG4148  146 RALLSSPRLLLMDEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSR 224
PhnT TIGR03258
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ...
 27-357 4.27e-28

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.


Pssm-ID: 132302 [Multi-domain]  Cd Length: 362  Bit Score: 115.86  E-value: 4.27e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   27 SFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdkKTSRIEGKVMLGGRDLLALPEEEmrkvrgKDI 106
Cdd:TIGR03258  10 HLRVAYGANTVLDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFV--KAAGLTGRIAIADRDLTHAPPHK------RGL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  107 SMIFQEpmTSLNPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVMIAMALASK 186
Cdd:TIGR03258  82 ALLFQN--YALFPHLKVEDNVAFGLRA-QKMPKADIAERVADALKLVGLGDAAAH---LPAQLSGGMQQRIAIARAIAIE 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  187 PKLLIADEPTTALDVTIQGQILDLIKTLQEE-EGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRGRHPYT 265
Cdd:TIGR03258 156 PDVLLLDEPLSALDANIRANMREEIAALHEElPELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDAPADGFA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  266 RALLSAVPKLGSMKERLLPARfPIIDIKTGE------SQPVADVKDTVSGGRTPILSVKDlttrfdiRSGLFGRKSGAVH 339
Cdd:TIGR03258 236 AEFLGAANILPAIALGITEAP-GLVDVSCGGavifafGDGRHDGRDKLACIRPEHLALTP-------RPAGEGRFHATIA 307

                         330       340
                  ....*....|....*....|....
gi 549799341  340 AVE------KVSFDLAEGETLSLV 357
Cdd:TIGR03258 308 SVEwhgaalHLLCDLDAACDEPML 331
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 343-547 4.83e-28

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 112.00  E-value: 4.83e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 343 KVSFDLaEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyeVLKLD---KTTLRTMRRSVQMIFQDpfASLDPRM 419
Cdd:cd03297   16 KIDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNG--TVLFDsrkKINLPPQQRKIGLVFQQ--YALFPHL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 420 SVGTAIMEPFIEHRLGTKQQareKAADLLEKVGLSPdMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSI 499
Cdd:cd03297   91 NVRENLAFGLKRKRNREDRI---SVDELLDLLGLDH-LLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRAL 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 549799341 500 KAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:cd03297  167 RLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
cbiO PRK13646
energy-coupling factor transporter ATPase;
340-550 6.10e-28

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 113.72  E-value: 6.10e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVL-KLDKTTLRTMRRSVQMIFQDPFASLdpr 418
Cdd:PRK13646  22 AIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITIThKTKDKYIRPVRKRIGMVFQFPESQL--- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 419 msvgtaiMEPFIEHRL--GTK------QQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:PRK13646  99 -------FEDTVEREIifGPKnfkmnlDEVKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDE 171

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341 491 AVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG-PRA 550
Cdd:PRK13646 172 PTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTsPKE 232
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 16-242 6.28e-28

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 112.14  E-value: 6.28e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFR---VDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLL------DkktsriEGKVML- 85
Cdd:COG4778    2 TTLLEVENLSKTFTlhlQGGKRLPVLDGVSFSVAAGECVALTGPSGAGKS----TLLKCIygnylpD------SGSILVr 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  86 ---GGRDLLALPEEEMRKVRGKDISMIFQ----EPMTSLNPIfpigkqIAEALtVHQDISSSAAKAEVIRLLEKVRIPna 158
Cdd:COG4778   72 hdgGWVDLAQASPREILALRRRTIGYVSQflrvIPRVSALDV------VAEPL-LERGVDREEARARARELLARLNLP-- 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 159 KNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDR 238
Cdd:COG4778  143 ERLWDLPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAK-ARGTAIIGIFHDEEVREAVADR 221


                 ....
gi 549799341 239 TIVM 242
Cdd:COG4778  222 VVDV 225
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 35-265 6.71e-28

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 112.83  E-value: 6.71e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  35 KSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRI--EGKVMLGGRDLLALPEEEMRKvrgkDISMIFQE 112
Cdd:PRK14246  23 KAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIkvDGKVLYFGKDIFQIDAIKLRK----EVGMVFQQ 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 113 PmtslNPiFP---IGKQIAEALTVHQDISSSAAKAEVIRLLEKVRI-PNAKNRFDDYPHQFSGGMRQRVMIAMALASKPK 188
Cdd:PRK14246  99 P----NP-FPhlsIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLwKEVYDRLNSPASQLSGGQQQRLTIARALALKPK 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 189 LLIADEPTTALDVTIQGQILDLIKTLQEEegMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRGRHPYT 265
Cdd:PRK14246 174 VLLMDEPTSMIDIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELT 248
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 336-543 7.41e-28

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 111.35  E-value: 7.41e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQDpfASL 415
Cdd:cd03292   12 NGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLRRKIGVVFQD--FRL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAIMEPF--IEHrlgTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVS 493
Cdd:cd03292   90 LPDRNVYENVAFALevTGV---PPREIRKRVPAALELVGLS-HKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTG 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 549799341 494 ALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEI 543
Cdd:cd03292  166 NLDPDTTWEI-MNLLKKINKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 16-543 8.80e-28

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 117.34  E-value: 8.80e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFrvdGGWKSVvRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLdkktSRI------EGKVMLGGRD 89
Cdd:PRK13549   3 EYLLEMKNITKTF---GGVKAL-DNVSLKVRAGEIVSLCGENGAGKS----TLMKVL----SGVyphgtyEGEIIFEGEE 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  90 LLAlpeEEMRKVRGKDISMIFQE-----PMTSLNPIFpIGKQIAEALTVHQDisssAAKAEVIRLLEKVRI---PNAKNR 161
Cdd:PRK13549  71 LQA---SNIRDTERAGIAIIHQElalvkELSVLENIF-LGNEITPGGIMDYD----AMYLRAQKLLAQLKLdinPATPVG 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 162 fddyphQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEeGMSVLFITHDMGVVAEVSDrTIV 241
Cdd:PRK13549 143 ------NLGLGQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISD-TIC 214

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 242 MFRGdvvetgttddifhrGRHPYTR--ALLSAVPKLGSMKERLLPARFPiidiktGESQPVADVkdtvsggrtpILSVKD 319
Cdd:PRK13549 215 VIRD--------------GRHIGTRpaAGMTEDDIITMMVGRELTALYP------REPHTIGEV----------ILEVRN 264

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 320 LTTRFDIRSGlfgRKSgavhaVEKVSFDLAEGETLSLVGESGCGKSTT---------GRSitrlieptSGDVMLDGYEVl 390
Cdd:PRK13549 265 LTAWDPVNPH---IKR-----VDDVSFSLRRGEILGIAGLVGAGRTELvqclfgaypGRW--------EGEIFIDGKPV- 327

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 391 KLdKTTLRTMRRSVQMIFQDPFA-SLDPRMSVGTAIMEPFI-----------EHRLGTKQQA----REKAADLLEKVGls 454
Cdd:PRK13549 328 KI-RNPQQAIAQGIAMVPEDRKRdGIVPVMGVGKNITLAALdrftggsriddAAELKTILESiqrlKVKTASPELAIA-- 404

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 455 pdmmrrfphEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHR 534
Cdd:PRK13549 405 ---------RLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEI-YKLINQLVQQGVAIIVISSELPEVLGLSDR 474


                 ....*....
gi 549799341 535 VAVMYLGEI 543
Cdd:PRK13549 475 VLVMHEGKL 483
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 267-550 9.08e-28

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 117.94  E-value: 9.08e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 267 ALLSAVPKLGSMK---ERLlparFPIIDiktgESQPVADVKDTVSGGRTPILSVKDLTtrfdirsglFGRKSGAVHAVEK 343
Cdd:COG4987  291 PLPAAAQHLGRVRaaaRRL----NELLD----APPAVTEPAEPAPAPGGPSLELEDVS---------FRYPGAGRPVLDG 353

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRtmrRSVQMIFQDP--FASldprmSV 421
Cdd:COG4987  354 LSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLR---RRIAVVPQRPhlFDT-----TL 425

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 422 GTAImepfiehRLGTKQQAREKAADLLEKVGLSpDMMRRFPH-----------EFSGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:COG4987  426 RENL-------RLARPDATDEELWAALERVGLG-DWLAALPDgldtwlgeggrRLSGGERRRLALARALLRDAPILLLDE 497

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 491 AVSALDVSIKAQVCnlLLDLQQNLNLAFLFISHDMAVVERVsHRVAVMYLGEIVEIGPRA 550
Cdd:COG4987  498 PTEGLDAATEQALL--ADLLEALAGRTVLLITHRLAGLERM-DRILVLEDGRIVEQGTHE 554
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 311-551 9.91e-28

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 111.76  E-value: 9.91e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 311 RTPILSVKDLTTRFdirsglfGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVL 390
Cdd:COG4181    5 SAPIIELRGLTKTV-------GTGAGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLF 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 391 KLD---KTTLRtmRRSVQMIFQDpFaSLDPRMsvgTA---IMEPfIEhrLGTKQQAREKAADLLEKVGLSpDMMRRFPHE 464
Cdd:COG4181   78 ALDedaRARLR--ARHVGFVFQS-F-QLLPTL---TAlenVMLP-LE--LAGRRDARARARALLERVGLG-HRLDHYPAQ 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 465 FSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEIV 544
Cdd:COG4181  147 LSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAAR-CDRVLRLRAGRLV 225


                 ....*..
gi 549799341 545 EIGPRAA 551
Cdd:COG4181  226 EDTAATA 232
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
340-548 1.42e-27

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 117.57  E-value: 1.42e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRtmrRSVQMIFQDP--FAsldp 417
Cdd:COG1132  355 VLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESLR---RQIGVVPQDTflFS---- 427

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 418 rMSVGTAImepfiehRLGTKQQAREKAADLLEKVGLSpDMMRRFPH-----------EFSGGQRQRIAIARSLMLDPKVI 486
Cdd:COG1132  428 -GTIRENI-------RYGRPDATDEEVEEAAKAAQAH-EFIEALPDgydtvvgergvNLSGGQRQRIAIARALLKDPPIL 498

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341 487 VADEAVSALDVSIKAQVcnllldlqqnlNLAF---------LFISHDMAVVERVsHRVAVMYLGEIVEIGP 548
Cdd:COG1132  499 ILDEATSALDTETEALI-----------QEALerlmkgrttIVIAHRLSTIRNA-DRILVLDDGRIVEQGT 557
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 39-245 1.54e-27

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 110.42  E-value: 1.54e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   39 RNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEMRKVRGKdISMIFQEpmTSLN 118
Cdd:TIGR02673  19 HDVSLHIRKGEFLFLTGPSGAGKT----TLLKLLYGALTPSRGQVRIAGEDVNRLRGRQLPLLRRR-IGVVFQD--FRLL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  119 PIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNaknRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTA 198
Cdd:TIGR02673  92 PDRTVYENVALPLEV-RGKKEREIQRRVGAALRQVGLEH---KADAFPEQLSGGEQQRVAIARAIVNSPPLLLADEPTGN 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 549799341  199 LDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:TIGR02673 168 LDPDLSERILDLLKRLN-KRGTTVIVATHDLSLVDRVAHRVIILDDG 213
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 53-266 1.59e-27

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 113.36  E-value: 1.59e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   53 IVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEmrkvrgKDISMIFQEpmTSLNPIFPIGKQIAEALT 132
Cdd:TIGR01187   1 LLGPSGCGKT----TLLRLLAGFEQPDSGSIMLDGEDVTNVPPHL------RHINMVFQS--YALFPHMTVEENVAFGLK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  133 VhQDISSSAAKAEVIRLLEKVripNAKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIK 212
Cdd:TIGR01187  69 M-RKVPRAEIKPRVLEALRLV---QLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELK 144

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 549799341  213 TLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFhrgRHPYTR 266
Cdd:TIGR01187 145 TIQEQLGITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIY---EEPANL 195
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 22-256 1.60e-27

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 112.88  E-value: 1.60e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  22 QNLTTSFrvdGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLS-IMRLLDKkTSrieGKVMLGGRDLLALPEEEMRk 100
Cdd:COG1125    5 ENVTKRY---PDGTVAVDDLSLTIPAGEFTVLVGPSGCGKT-TTLRmINRLIEP-TS---GRILIDGEDIRDLDPVELR- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 101 vRGkdismifqepmtslnpifpIGKQIAEA-----LTVHQDI---------SSSAAKAEVIRLLEKVRIPNAKNRfDDYP 166
Cdd:COG1125   76 -RR-------------------IGYVIQQIglfphMTVAENIatvprllgwDKERIRARVDELLELVGLDPEEYR-DRYP 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 167 HQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGD 246
Cdd:COG1125  135 HELSGGQQQRVGVARALAADPPILLMDEPFGALDPITREQLQDELLRLQRELGKTIVFVTHDIDEALKLGDRIAVMREGR 214

                        250
                 ....*....|
gi 549799341 247 VVETGTTDDI 256
Cdd:COG1125  215 IVQYDTPEEI 224
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
311-556 2.00e-27

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 114.27  E-value: 2.00e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 311 RTPILSVKDLTTRFDIRSglfgrksgavhAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVl 390
Cdd:PRK09452  11 LSPLVELRGISKSFDGKE-----------VISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDI- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 391 kldkTTLRTMRRSVQMIFQDpFAsLDPRMSVgtaimepFIEHRLGTKQQAREKA------ADLLEKVGLSpDMMRRFPHE 464
Cdd:PRK09452  79 ----THVPAENRHVNTVFQS-YA-LFPHMTV-------FENVAFGLRMQKTPAAeitprvMEALRMVQLE-EFAQRKPHQ 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 465 FSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIV 544
Cdd:PRK09452 145 LSGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIE 224

                        250
                 ....*....|..
gi 549799341 545 EIGPRAAVFDNP 556
Cdd:PRK09452 225 QDGTPREIYEEP 236
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
19-272 3.26e-27

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 110.98  E-value: 3.26e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLttSFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEM 98
Cdd:COG4559    2 LEAENL--SVRLGG--RTLLDDVSLTLRPGELTAIIGPNGAGKS----TLLKLLTGELTPSSGEVRLNGRPLAAWSPWEL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGkdisMIFQEpmTSLNPIFPIGKQIAEALTVHQdiSSSAAKAEVIRL-LEKVRIPNAKNRfdDYPhQFSGGMRQRV 177
Cdd:COG4559   74 ARRRA----VLPQH--SSLAFPFTVEEVVALGRAPHG--SSAAQDRQIVREaLALVGLAHLAGR--SYQ-TLSGGEQQRV 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 178 MIAMALA-------SKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVET 250
Cdd:COG4559  143 QLARVLAqlwepvdGGPRWLFLDEPTSALDLAHQHAVLRLARQLA-RRGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQ 221

                        250       260
                 ....*....|....*....|..
gi 549799341 251 GTTDDIFhrgrhpyTRALLSAV 272
Cdd:COG4559  222 GTPEEVL-------TDELLERV 236
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 18-238 4.38e-27

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 109.48  E-value: 4.38e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEE 97
Cdd:PRK10584   6 IVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALIGESGSGKS-TLLAILAGLDDGSS---GEVSLVGQPLHQMDEEA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 MRKVRGKDISMIFQEPM--TSLNPIFPIgkQIAEALtvhQDISSSAAKAEVIRLLEKVRIpnaKNRFDDYPHQFSGGMRQ 175
Cdd:PRK10584  82 RAKLRAKHVGFVFQSFMliPTLNALENV--ELPALL---RGESSRQSRNGAKALLEQLGL---GKRLDHLPAQLSGGEQQ 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDR 238
Cdd:PRK10584 154 RVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAARCDRR 216
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
33-274 4.39e-27

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 110.44  E-value: 4.39e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  33 GWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTsriEGKVMLGGRD----------LLALPEEEMRKVR 102
Cdd:PRK10619  16 GEHEVLKGVSLQANAGDVISIIGSSGSGKS-TFLRCINFLEKPS---EGSIVVNGQTinlvrdkdgqLKVADKNQLRLLR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 103 GKdISMIFQE-----PMTSLnpifpigKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNrfDDYPHQFSGGMRQRV 177
Cdd:PRK10619  92 TR-LTMVFQHfnlwsHMTVL-------ENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQ--GKYPVHLSGGQQQRV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIF 257
Cdd:PRK10619 162 SIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLA-EEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLF 240

                        250
                 ....*....|....*..
gi 549799341 258 HRGRHPYTRALLSAVPK 274
Cdd:PRK10619 241 GNPQSPRLQQFLKGSLK 257
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 21-535 4.45e-27

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 115.16  E-value: 4.45e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  21 VQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGR--------DLLA 92
Cdd:COG0488    1 LENLSKSF----GGRPLLDDVSLSINPGDRIGLVGRNGAGKS----TLLKILAGELEPDSGEVSIPKGlrigylpqEPPL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  93 LPE----EEMRKVRG--KDISMIFQEPMTSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKnrFDDYP 166
Cdd:COG0488   73 DDDltvlDTVLDGDAelRALEAELEELEAKLAEPDEDLERLAELQEEFEALGGWEAEARAEEILSGLGFPEED--LDRPV 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 167 HQFSGGMRQRVMIAMALASKPKLLIADEPTTALDvtIQGqILDLIKTLQEEEGmSVLFITHD-------MGVVAEVSDRT 239
Cdd:COG0488  151 SELSGGWRRRVALARALLSEPDLLLLDEPTNHLD--LES-IEWLEEFLKNYPG-TVLVVSHDryfldrvATRILELDRGK 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 240 IVMFRGDvvetgttddifhrgrhpYT------------------------RALLSAVPKLG----------SMKERLlpA 285
Cdd:COG0488  227 LTLYPGN-----------------YSayleqraerleqeaaayakqqkkiAKEEEFIRRFRakarkakqaqSRIKAL--E 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 286 RFPIIDIKTGESQPVADVKDTVSGGRtPILSVKDLTTRFDirsglfGRKsgavhAVEKVSFDLAEGETLSLVGESGCGKS 365
Cdd:COG0488  288 KLEREEPPRRDKTVEIRFPPPERLGK-KVLELEGLSKSYG------DKT-----LLDDLSLRIDRGDRIGLIGPNGAGKS 355

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 366 TTGRSITRLIEPTSGDVmldgyevlKLDKTtlrtmrrsVQMIF--QDpFASLDPRMSVgtaimepfIEH-RLGTKQQARE 442
Cdd:COG0488  356 TLLKLLAGELEPDSGTV--------KLGET--------VKIGYfdQH-QEELDPDKTV--------LDElRDGAPGGTEQ 410

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 443 KAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADE--------AVSALDVSIKaqvcnllldlqqnl 514
Cdd:COG0488  411 EVRGYLGRFLFSGDDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEptnhldieTLEALEEALD-------------- 476

                        570       580
                 ....*....|....*....|....*
gi 549799341 515 nlAF----LFISHDMAVVERVSHRV 535
Cdd:COG0488  477 --DFpgtvLLVSHDRYFLDRVATRI 499
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 40-251 4.52e-27

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 109.31  E-value: 4.52e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  40 NMSFEIaPRETVAIVGESGSGKSvTSLSIMRLLDKKTS---RIEGKVMLGGRDLLALPEEEMRkvrgkdISMIFQEpmTS 116
Cdd:cd03297   16 KIDFDL-NEEVTGIFGASGAGKS-TLLRCIAGLEKPDGgtiVLNGTVLFDSRKKINLPPQQRK------IGLVFQQ--YA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 117 LNPIFPIGKQIAEALTVHqdiSSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVMIAMALASKPKLLIADEPT 196
Cdd:cd03297   86 LFPHLNVRENLAFGLKRK---RNREDRISVDELLDLLGLDHLLNR---YPAQLSGGEKQRVALARALAAQPELLLLDEPF 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 197 TALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:cd03297  160 SALDRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 331-547 8.81e-27

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 109.11  E-value: 8.81e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 331 FGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLrtmRRSVQMIFQ- 409
Cdd:cd03252    8 FRYKPDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWL---RRQVGVVLQe 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 410 ---------DPFASLDPRMSVGTAI-------MEPFI-EHRLGTKQQAREKAADLlekvglspdmmrrfphefSGGQRQR 472
Cdd:cd03252   85 nvlfnrsirDNIALADPGMSMERVIeaaklagAHDFIsELPEGYDTIVGEQGAGL------------------SGGQRQR 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 473 IAIARSLMLDPKVIVADEAVSALDVsiKAQVCNLLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEIVEIG 547
Cdd:cd03252  147 IAIARALIHNPRILIFDEATSALDY--ESEHAIMRNMHDICAGRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQG 218
cbiO PRK13650
energy-coupling factor transporter ATPase;
18-260 9.28e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 110.21  E-value: 9.28e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKSVTslsiMRLLDKKTSRIEGKVMLGGRdllALPEEE 97
Cdd:PRK13650   4 IIEVKNLTFKYKEDQE-KYTLNDVSFHVKQGEWLSIIGHNGSGKSTT----VRLIDGLLEAESGQIIIDGD---LLTEEN 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 MRKVRGKdISMIFQEPmtslnpifpiGKQIAEAlTVHQD---------ISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQ 168
Cdd:PRK13650  76 VWDIRHK-IGMVFQNP----------DNQFVGA-TVEDDvafglenkgIPHEEMKERVNEALELVGMQDFKER---EPAR 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVtiQGQiLDLIKTLQ---EEEGMSVLFITHDMGVVAeVSDRTIVMFRG 245
Cdd:PRK13650 141 LSGGQKQRVAIAGAVAMRPKIIILDEATSMLDP--EGR-LELIKTIKgirDDYQMTVISITHDLDEVA-LSDRVLVMKNG 216

                        250
                 ....*....|....*
gi 549799341 246 DVVETGTTDDIFHRG 260
Cdd:PRK13650 217 QVESTSTPRELFSRG 231
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 20-248 9.48e-27

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 108.11  E-value: 9.48e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  20 SVQNLTTSFrvdGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLlalpeeeMR 99
Cdd:cd03226    1 RIENISFSY---KKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKES----SGSILLNGKPI-------KA 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 100 KVRGKDISMIFQEPMTSLnpifpIGKQIAEALTVHQDISSsAAKAEVIRLLEKVRIPNAKnrfDDYPHQFSGGMRQRVMI 179
Cdd:cd03226   67 KERRKSIGYVMQDVDYQL-----FTDSVREELLLGLKELD-AGNEQAETVLKDLDLYALK---ERHPLSLSGGQKQRLAI 137

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 180 AMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:cd03226  138 AAALLSGKDLLIFDEPTSGLDYKNMERVGELIRELA-AQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
27-252 1.42e-26

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 114.49  E-value: 1.42e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  27 SFRVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKS-VTSLsIMRLLDKKtsriEGKVMLGGRDLLALPEEEMRKVrgkd 105
Cdd:COG1132  346 SFSYPGD-RPVLKDISLTIPPGETVALVGPSGSGKStLVNL-LLRFYDPT----SGRILIDGVDIRDLTLESLRRQ---- 415

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 106 ISMIFQEPMtslnpIFpigkqiaeALTVHQDIS---SSAAKAEVIRLLEKVripNAKNRFDDYPHQF-----------SG 171
Cdd:COG1132  416 IGVVPQDTF-----LF--------SGTIRENIRygrPDATDEEVEEAAKAA---QAHEFIEALPDGYdtvvgergvnlSG 479

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 172 GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeeEGMSVLFITHDMGVVAEVsDRTIVMFRGDVVETG 251
Cdd:COG1132  480 GQRQRIAIARALLKDPPILILDEATSALDTETEALIQEALERLM--KGRTTIVIAHRLSTIRNA-DRILVLDDGRIVEQG 556


                 .
gi 549799341 252 T 252
Cdd:COG1132  557 T 557
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
35-257 1.64e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 109.41  E-value: 1.64e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  35 KSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDllALPEEEMRKVRGKdISMIFQEPm 114
Cdd:PRK13633  23 KLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPS----EGKVYVDGLD--TSDEENLWDIRNK-AGMVFQNP- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 115 tslnpifpiGKQIAeALTVHQDIS----SSAAKAEVIRLlekvRIPNAKNRFDDY------PHQFSGGMRQRVMIAMALA 184
Cdd:PRK13633  95 ---------DNQIV-ATIVEEDVAfgpeNLGIPPEEIRE----RVDESLKKVGMYeyrrhaPHLLSGGQKQRVAIAGILA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 185 SKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEvSDRTIVMFRGDVVETGTTDDIF 257
Cdd:PRK13633 161 MRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIF 232
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
315-556 1.78e-26

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 110.96  E-value: 1.78e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKldk 394
Cdd:PRK11432   7 VVLKNITKRF-----------GSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTH--- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 ttlrtmrRSVQ-----MIFQDpfASLDPRMSVGTAI-----MepfiehrLG-TKQQAREKAADLLEKVGLSpDMMRRFPH 463
Cdd:PRK11432  73 -------RSIQqrdicMVFQS--YALFPHMSLGENVgyglkM-------LGvPKEERKQRVKEALELVDLA-GFEDRYVD 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 464 EFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEI 543
Cdd:PRK11432 136 QISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKI 215

                        250
                 ....*....|...
gi 549799341 544 VEIGPRAAVFDNP 556
Cdd:PRK11432 216 MQIGSPQELYRQP 228
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 18-328 2.05e-26

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 109.43  E-value: 2.05e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLLA----- 92
Cdd:COG4152    1 MLELKGLTKRF----GDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPD----SGEVLWDGEPLDPedrrr 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  93 ---LPEEemrkvRGkdismifqepmtsLNPIFPIGKQIAEALTVHqDISSSAAKAEVIRLLEKVRIPNAKNRfddyP-HQ 168
Cdd:COG4152   73 igyLPEE-----RG-------------LYPKMKVGEQLVYLARLK-GLSKAEAKRRADEWLERLGLGDRANK----KvEE 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:COG4152  130 LSKGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELA-AKGTTVIFSSHQMELVEELCDRIVIINKGRKV 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 249 ETGTTDDIfhRGRHPYTRALLSAVPKLGsmkerLLPARFPIIDIKTGESQPVADVKDTVSGGrtPILsvKDLTTRFDIRS 328
Cdd:COG4152  209 LSGSVDEI--RRQFGRNTLRLEADGDAG-----WLRALPGVTVVEEDGDGAELKLEDGADAQ--ELL--RALLARGPVRE 277
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 19-251 2.37e-26

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 106.98  E-value: 2.37e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLL--DKKTSRIEGKVM--LGGRDLLALP 94
Cdd:cd03269    1 LEVENVTKRF----GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIIlpDSGEVLFDGKPLdiAARNRIGYLP 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 EEE--MRKVRGKDISMIFqepmTSLnpifpigkqiaealtvhQDISSSAAKAEVIRLLEKVRIPNAKNRFDDyphQFSGG 172
Cdd:cd03269   77 EERglYPKMKVIDQLVYL----AQL-----------------KGLKKEEARRRIDEWLERLELSEYANKRVE---ELSKG 132

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 173 MRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:cd03269  133 NQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKDVIRELA-RAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 314-547 2.42e-26

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 107.07  E-value: 2.42e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFDIrsglfgrKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLD 393
Cdd:cd03266    1 MITADALTKRFRD-------VKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 KTTLRTMRrsvqmIFQDPFAsLDPRMSVgTAIMEPFieHRL-GTKQQAREKAAD-LLEKVGLSPDMMRRfPHEFSGGQRQ 471
Cdd:cd03266   74 AEARRRLG-----FVSDSTG-LYDRLTA-RENLEYF--AGLyGLKGDELTARLEeLADRLGMEELLDRR-VGGFSTGMRQ 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 472 RIAIARSLMLDPKVIVADEAVSALDVsIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:cd03266  144 KVAIARALVHDPPVLLLDEPTTGLDV-MATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 343-560 3.40e-26

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 110.20  E-value: 3.40e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  343 KVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyEVLK--LDKTTLRTMRRSVQMIFQDpfASLDPRMS 420
Cdd:TIGR02142  15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNG-RTLFdsRKGIFLPPEKRRIGYVFQE--ARLFPHLS 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  421 VGTAIMEPFIEHRLGTKQQAREKAADLLekvGLSPdMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIK 500
Cdd:TIGR02142  92 VRGNLRYGMKRARPSERRISFERVIELL---GIGH-LLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRK 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  501 AQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPY 560
Cdd:TIGR02142 168 YEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPW 227
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 344-556 3.63e-26

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 110.19  E-value: 3.63e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyEVLkLD---KTTLRTMRRSVQMIFQDpfASLDPRMS 420
Cdd:COG4148   18 VDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGG-EVL-QDsarGIFLPPHRRRIGYVFQE--ARLFPHLS 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 421 V------GtaimepfieHRLGTKQQAREKAADLLEKVGLSPdMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:COG4148   94 VrgnllyG---------RKRAPRAERRISFDEVVELLGIGH-LLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAA 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 495 LDVSIKAQVcnllldlqqnlnLAFL------------FISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNP 556
Cdd:COG4148  164 LDLARKAEI------------LPYLerlrdeldipilYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRP 225
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 315-544 3.84e-26

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 104.82  E-value: 3.84e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDk 394
Cdd:cd03216    1 LELRGITKRF-----------GGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFAS- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 tTLRTMRRSVQMIFQdpfasldprmsvgtaimepfiehrlgtkqqarekaadllekvglspdmmrrfpheFSGGQRQRIA 474
Cdd:cd03216   69 -PRDARRAGIAMVYQ-------------------------------------------------------LSVGERQMVE 92

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 475 IARSLMLDPKVIVADEAVSALDVS-----------IKAQvcnllldlqqnlNLAFLFISHDMAVVERVSHRVAVMYLGEI 543
Cdd:cd03216   93 IARALARNARLLILDEPTAALTPAeverlfkvirrLRAQ------------GVAVIFISHRLDEVFEIADRVTVLRDGRV 160


                 .
gi 549799341 544 V 544
Cdd:cd03216  161 V 161
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 340-547 6.38e-26

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 106.55  E-value: 6.38e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLdktTLRTMRRSVQMIFQDPFasldprM 419
Cdd:cd03251   17 VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDY---TLASLRRQIGLVSQDVF------L 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 420 SVGTaIMEPFIEHRLGTKQQAREKAAdlleKVGLSPDMMRRFPHEF-----------SGGQRQRIAIARSLMLDPKVIVA 488
Cdd:cd03251   88 FNDT-VAENIAYGRPGATREEVEEAA----RAANAHEFIMELPEGYdtvigergvklSGGQRQRIAIARALLKDPPILIL 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 489 DEAVSALDVSIKAQVCNLLLDLQQNLNLafLFISHDMAVVERvSHRVAVMYLGEIVEIG 547
Cdd:cd03251  163 DEATSALDTESERLVQAALERLMKNRTT--FVIAHRLSTIEN-ADRIVVLEDGKIVERG 218
cbiO PRK13650
energy-coupling factor transporter ATPase;
314-543 7.37e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 107.51  E-value: 7.37e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFDirsglfgrKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEvlkLD 393
Cdd:PRK13650   4 IIEVKNLTFKYK--------EDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDL---LT 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 KTTLRTMRRSVQMIFQDPfaslDPRMsVGtAIMEPFIEHRLGTK----QQAREKAADLLEKVGLSpDMMRRFPHEFSGGQ 469
Cdd:PRK13650  73 EENVWDIRHKIGMVFQNP----DNQF-VG-ATVEDDVAFGLENKgiphEEMKERVNEALELVGMQ-DFKEREPARLSGGQ 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 470 RQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVErVSHRVAVMYLGEI 543
Cdd:PRK13650 146 KQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEVA-LSDRVLVMKNGQV 218
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 18-543 9.38e-26

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 111.07  E-value: 9.38e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   18 VLSVQNLTTSFrvdGGWKSVvRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDK--KTSRIEGKVMLGGRDLLAlpe 95
Cdd:TIGR02633   1 LLEMKGIVKTF---GGVKAL-DGIDLEVRPGECVGLCGENGAGKS----TLMKILSGvyPHGTWDGEIYWSGSPLKA--- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   96 EEMRKVRGKDISMIFQE-----PMTSLNPIFpIGKQIA-EALTVHQDISSSAAKAevirLLEKVRIPNAKNRFDdyPHQF 169
Cdd:TIGR02633  70 SNIRDTERAGIVIIHQEltlvpELSVAENIF-LGNEITlPGGRMAYNAMYLRAKN----LLRELQLDADNVTRP--VGDY 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDrTIVMFRGdvve 249
Cdd:TIGR02633 143 GGGQQQLVEIAKALNKQARLLILDEPSSSLTEKETEILLDIIRDLK-AHGVACVYISHKLNEVKAVCD-TICVIRD---- 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  250 tgttddifhrGRHPYTRAL--LSAVPKLGSMKERLLPARFPiidiktGESQPVADVkdtvsggrtpILSVKDLTTrFDIR 327
Cdd:TIGR02633 217 ----------GQHVATKDMstMSEDDIITMMVGREITSLYP------HEPHEIGDV----------ILEARNLTC-WDVI 269

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  328 SGLFGRksgavhaVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPT-SGDVMLDGYEVLKldKTTLRTMRRSVQM 406
Cdd:TIGR02633 270 NPHRKR-------VDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKPVDI--RNPAQAIRAGIAM 340

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  407 IFQD-PFASLDPRMSVGTAIMEPFIEHRLG-------TKQQAREKAADLLEKVGLSPDMmrrfP-HEFSGGQRQRIAIAR 477
Cdd:TIGR02633 341 VPEDrKRHGIVPILGVGKNITLSVLKSFCFkmridaaAELQIIGSAIQRLKVKTASPFL----PiGRLSGGNQQKAVLAK 416

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341  478 SLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEI 543
Cdd:TIGR02633 417 MLLTNPRVLILDEPTRGVDVGAKYEI-YKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKL 481
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 344-544 9.81e-26

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 105.03  E-value: 9.81e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyevlklDKTTLRTMRRSVQMIFQDP----FASldprm 419
Cdd:cd03226   19 LSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNG------KPIKAKERRKSIGYVMQDVdyqlFTD----- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 420 SVgtaimepFIEHRLGTKQQAR--EKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:cd03226   88 SV-------REELLLGLKELDAgnEQAETVLKDLDLY-ALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDY 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 549799341 498 SIKAQVCnLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIV 544
Cdd:cd03226  160 KNMERVG-ELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 51-260 9.94e-26

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 107.41  E-value: 9.94e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  51 VAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEMRKVRGKDISMIFQepmtslnpiFPiGKQIAEA 130
Cdd:PRK13634  36 VAIIGHTGSGKS-TLLQHLNGLLQPTS---GTVTIGERVITAGKKNKKLKPLRKKVGIVFQ---------FP-EHQLFEE 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 131 lTVHQDI---------SSSAAKAEVIRLLEKVRIPNAKnrFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDV 201
Cdd:PRK13634 102 -TVEKDIcfgpmnfgvSEEDAKQKAREMIELVGLPEEL--LARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDP 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 202 TIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRG 260
Cdd:PRK13634 179 KGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADP 237
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 340-557 1.04e-25

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 107.09  E-value: 1.04e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyEVLKLDKTTLRTMRRSVQMIFQDP----FAsl 415
Cdd:PRK13639  17 ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKG-EPIKYDKKSLLEVRKTVGIVFQNPddqlFA-- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 dPRMSVGTAimepFIEHRLG-TKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:PRK13639  94 -PTVEEDVA----FGPLNLGlSKEEVEKRVKEALKAVGME-GFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSG 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 495 LDVSIKAQVCNLLLDLQQNLNLafLFIS-HDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQ 557
Cdd:PRK13639 168 LDPMGASQIMKLLYDLNKEGIT--IIIStHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDIE 229
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
19-272 1.33e-25

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 106.25  E-value: 1.33e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTsrieGKVMLGGRDLLALPEEEM 98
Cdd:PRK11231   3 LRTENLTVGY----GTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQS----GTVFLGDKPISMLSSRQL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 rkvrGKDISMIFQEPMTSlnpifpigkqiaEALTVHQDIS-------------SSAAKAEVIRLLEKVRIPN-AKNRFDD 164
Cdd:PRK11231  75 ----ARRLALLPQHHLTP------------EGITVRELVAygrspwlslwgrlSAEDNARVNQAMEQTRINHlADRRLTD 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 165 yphqFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFR 244
Cdd:PRK11231 139 ----LSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELN-TQGKTVVTVLHDLNQASRYCDHLVVLAN 213

                        250       260
                 ....*....|....*....|....*...
gi 549799341 245 GDVVETGTTDDIFhrgrhpyTRALLSAV 272
Cdd:PRK11231 214 GHVMAQGTPEEVM-------TPGLLRTV 234
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 8-552 1.46e-25

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 110.53  E-value: 1.46e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   8 MEQTGGSVSPVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGG 87
Cdd:PRK15439   1 MQTSDTTAPPLLCARSISKQY----SGVEVLKGIDFTLHAGEVHALLGGNGAGKS----TLMKIIAGIVPPDSGTLEIGG 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  88 RDLLALPEEEMRKVrgkDISMIFQEPMtslnpIFPigkqiaeALTVHQDISSSAAKAEVI--RLLEKVRIPNAKNRFDDY 165
Cdd:PRK15439  73 NPCARLTPAKAHQL---GIYLVPQEPL-----LFP-------NLSVKENILFGLPKRQASmqKMKQLLAALGCQLDLDSS 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 166 PHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEeGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:PRK15439 138 AGSLEVADRQIVEILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRDG 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 246 DVVETGTTDDIfhrgrhpYTRALLSAVPKlGSMKERLLPARFPIIDIKTGESQPVADvkdtvsggrTPILSVKDLTtrfd 325
Cdd:PRK15439 217 TIALSGKTADL-------STDDIIQAITP-AAREKSLSASQKLWLELPGNRRQQAAG---------APVLTVEDLT---- 275

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 326 irsglfgrKSGAVHavekVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDktTLRTMRRSVQ 405
Cdd:PRK15439 276 --------GEGFRN----ISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALS--TAQRLARGLV 341

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 406 MIFQDPFAS---LDPRMSVGTAimePFIEHRLGTKQQ-AREKAadLLEKVGLSpdMMRRFPHE------FSGGQRQRIAI 475
Cdd:PRK15439 342 YLPEDRQSSglyLDAPLAWNVC---ALTHNRRGFWIKpARENA--VLERYRRA--LNIKFNHAeqaartLSGGNQQKVLI 414

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 476 ARSLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAV 552
Cdd:PRK15439 415 AKCLEASPQLLIVDEPTRGVDVSARNDI-YQLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQGEISGALTGAAI 490
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 346-547 2.29e-25

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 104.11  E-value: 2.29e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 346 FDL--AEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyevlkLDKTTLRTMRRSVQMIFQDP--FASLDPRMSV 421
Cdd:cd03298   17 FDLtfAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLING-----VDVTAAPPADRPVSMLFQENnlFAHLTVEQNV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 422 GTAIMEpfiehRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKA 501
Cdd:cd03298   92 GLGLSP-----GLKLTAEDRQAIEVALARVGLA-GLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRA 165

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 549799341 502 QVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:cd03298  166 EMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 315-547 2.35e-25

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 104.28  E-value: 2.35e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDK 394
Cdd:cd03269    1 LEVENVTKRF-----------GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAAR 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 TTL----------RTMRRSVQMIFqdpFASLdprmsvgtaimepfiehRLGTKQQAREKAADLLEKVGLSPDMMRRFpHE 464
Cdd:cd03269   70 NRIgylpeerglyPKMKVIDQLVY---LAQL-----------------KGLKKEEARRRIDEWLERLELSEYANKRV-EE 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 465 FSGGQRQRIAIARSLMLDPKVIVADEAVSALDVsIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIV 544
Cdd:cd03269  129 LSKGNQQKVQFIAAVIHDPELLILDEPFSGLDP-VNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAV 207


                 ...
gi 549799341 545 EIG 547
Cdd:cd03269  208 LYG 210
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 312-554 2.37e-25

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 105.17  E-value: 2.37e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyevlk 391
Cdd:COG1121    4 MPAIELENLTVSY-----------GGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFG----- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 392 ldkTTLRTMRRSV----QMifqdpfASLDPR--MSVGTAIMEPFIEHR---LGTKQQAREKAADLLEKVGLSpDMMRRFP 462
Cdd:COG1121   68 ---KPPRRARRRIgyvpQR------AEVDWDfpITVRDVVLMGRYGRRglfRRPSRADREAVDEALERVGLE-DLADRPI 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 463 HEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV-----------SIKAQVCnllldlqqnlnlAFLFISHDMAVVERV 531
Cdd:COG1121  138 GELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAateealyellrELRREGK------------TILVVTHDLGAVREY 205

                        250       260
                 ....*....|....*....|...
gi 549799341 532 SHRVAVMyLGEIVEIGPRAAVFD 554
Cdd:COG1121  206 FDRVLLL-NRGLVAHGPPEEVLT 227
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 17-228 2.54e-25

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 103.71  E-value: 2.54e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLttSFRVDGGWksVVRNMSFEIAPRETVAIVGESGSGKsvTSLsiMRLLDKKTSRIEGKVMLGGRDLLALPEE 96
Cdd:COG4133    1 MMLEAENL--SCRRGERL--LFSGLSFTLAAGEALALTGPNGSGK--TTL--LRILAGLLPPSAGEVLWNGEPIRDARED 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  97 emrkvRGKDISMIFQEPM--TSLNPifpigkqiAEALTVHQDISSSAAKAEVI-RLLEKVRIPNAKNRFddyPHQFSGGM 173
Cdd:COG4133   73 -----YRRRLAYLGHADGlkPELTV--------RENLRFWAALYGLRADREAIdEALEAVGLAGLADLP---VRQLSAGQ 136

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 174 RQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMsVLFITHD 228
Cdd:COG4133  137 KRRVALARLLLSPAPLWLLDEPFTALDAAGVALLAELIAAHLARGGA-VLLTTHQ 190
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 287-551 2.77e-25

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 110.23  E-value: 2.77e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 287 FPIIDiktGESQPVADVKDTVSGGRTPILSVKDLTTRFDirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKST 366
Cdd:COG4988  312 FALLD---APEPAAPAGTAPLPAAGPPSIELEDVSFSYP----------GGRPALDGLSLTIPPGERVALVGPSGAGKST 378

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 367 TGRSITRLIEPTSGDVMLDGYEVLKLDKTTLrtmRRSVQMIFQDP--FAsldprmsvGTaIMEpFIehRLGTKQQAREKA 444
Cdd:COG4988  379 LLNLLLGFLPPYSGSILINGVDLSDLDPASW---RRQIAWVPQNPylFA--------GT-IRE-NL--RLGRPDASDEEL 443

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 445 ADLLEKVGLSpDMMRRFPHEF-----------SGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVcnLLLDLQQN 513
Cdd:COG4988  444 EAALEAAGLD-EFVAALPDGLdtplgeggrglSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEI--LQALRRLA 520

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 549799341 514 LNLAFLFISHDMAVVERVSHRVaVMYLGEIVEIGPRAA 551
Cdd:COG4988  521 KGRTVILITHRLALLAQADRIL-VLDDGRIVEQGTHEE 557
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 38-262 2.78e-25

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 104.47  E-value: 2.78e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   38 VRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLAlpeeemrkvRGKDISMIFQEpmTSL 117
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKS-TLLNLISGLAQPTS---GGVILEGKQITE---------PGPDRMVVFQN--YSL 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  118 NPIFPIGKQIAEAL-TVHQDISSSAAKAEVIRLLEKVRIPNAKnrfDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPT 196
Cdd:TIGR01184  66 LPWLTVRENIALAVdRVLPDLSKSERRAIVEEHIALVGLTEAA---DKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPF 142

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341  197 TALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDI-FHRGRH 262
Cdd:TIGR01184 143 GALDALTRGNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQILEVpFPRPRD 209
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 341-563 2.84e-25

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 105.13  E-value: 2.84e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyEVLKLDKTTLR----TMRRSVQMIFQDPfaSLD 416
Cdd:PRK14246  26 LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDG-KVLYFGKDIFQidaiKLRKEVGMVFQQP--NPF 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 417 PRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRF---PHEFSGGQRQRIAIARSLMLDPKVIVADEAVS 493
Cdd:PRK14246 103 PHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLWKEVYDRLnspASQLSGGQQQRLTIARALALKPKVLLMDEPTS 182

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 494 ALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKK 563
Cdd:PRK14246 183 MIDIVNSQAI--EKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEK 250
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
16-229 3.09e-25

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 104.51  E-value: 3.09e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPE 95
Cdd:PRK11629   3 KILLQCDNLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKS-TLLHLLGGLDTPTS---GDVIFNGQPMSKLSS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGKDISMIFQepMTSLNPIFPIGKQIAEALTVHQDISSSAAKaeviRLLEKVRIPNAKNRFDDYPHQFSGGMRQ 175
Cdd:PRK11629  79 AAKAELRNQKLGFIYQ--FHHLLPDFTALENVAMPLLIGKKKPAEINS----RALEMLAAVGLEHRANHRPSELSGGERQ 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDM 229
Cdd:PRK11629 153 RVAIARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDL 206
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 19-236 3.10e-25

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 103.72  E-value: 3.10e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTtsfrVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLS-IMRLLDKKTSrIEGKVMLGGRDLLALPEEE 97
Cdd:COG4136    2 LSLENLT----ITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKS-TLLAaIAGTLSPAFS-ASGEVLLNGRRLTALPAEQ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 MRkvrgkdISMIFQEPMtsLNPIFPIGKQIAEALTvhQDISSSAAKAEVIRLLEKVripNAKNRFDDYPHQFSGGMRQRV 177
Cdd:COG4136   76 RR------IGILFQDDL--LFPHLSVGENLAFALP--PTIGRAQRRARVEQALEEA---GLAGFADRDPATLSGGQRARV 142

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVS 236
Cdd:COG4136  143 ALLRALLAEPRALLLDEPFSKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDAPAAG 201
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
344-535 3.61e-25

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 104.13  E-value: 3.61e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMR-RSVQMIFQdpFASLDPRMSVG 422
Cdd:PRK11629  28 VSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRnQKLGFIYQ--FHHLLPDFTAL 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 423 TAIMEPFIehrLGTK--QQAREKAADLLEKVGLSPDMMRRfPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIK 500
Cdd:PRK11629 106 ENVAMPLL---IGKKkpAEINSRALEMLAAVGLEHRANHR-PSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNA 181

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 549799341 501 AQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRV 535
Cdd:PRK11629 182 DSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQL 216
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 344-503 3.62e-25

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 104.54  E-value: 3.62e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDkttLRTMRRSVQMIFQDP--FAsldprmsv 421
Cdd:cd03249   22 LSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLN---LRWLRSQIGLVSQEPvlFD-------- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 422 gTAIMEPFIEHRLGTKQQAREKAAdlleKVGLSPDMMRRFPHEF-----------SGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:cd03249   91 -GTIAENIRYGKPDATDEEVEEAA----KKANIHDFIMSLPDGYdtlvgergsqlSGGQKQRIAIARALLRNPKILLLDE 165

                        170
                 ....*....|...
gi 549799341 491 AVSALDVSIKAQV 503
Cdd:cd03249  166 ATSALDAESEKLV 178
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 336-547 4.18e-25

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 102.51  E-value: 4.18e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRrsvqmifqdpfasl 415
Cdd:cd03214   10 GGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKI-------------- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 dprmsvgtAIMEpfiehrlgtkqQArekaadlLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSAL 495
Cdd:cd03214   76 --------AYVP-----------QA-------LELLGLA-HLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHL 128

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 549799341 496 DVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:cd03214  129 DIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 312-538 4.79e-25

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 103.67  E-value: 4.79e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFDI--RSGLfgrksgAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLD-GYE 388
Cdd:COG4778    2 TTLLEVENLSKTFTLhlQGGK------RLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRhDGG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 389 VLKLDKTTLRTM----RRSVQMIFQdpFASLDPRMSVGTAIMEPFIEhrLGT-KQQAREKAADLLEKVGLSPDMMRRFPH 463
Cdd:COG4778   76 WVDLAQASPREIlalrRRTIGYVSQ--FLRVIPRVSALDVVAEPLLE--RGVdREEARARARELLARLNLPERLWDLPPA 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 464 EFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVM 538
Cdd:COG4778  152 TFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVV-VELIEEAKARGTAIIGIFHDEEVREAVADRVVDV 225
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
313-524 5.02e-25

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 104.56  E-value: 5.02e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFdirsglfGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkl 392
Cdd:COG4525    2 SMLTVRHVSVRY-------PGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPV--- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 393 dktTLRTMRRSVqmIFQDpfASLDPRMSVGTAIMEPFIEHRLGtKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQR 472
Cdd:COG4525   72 ---TGPGADRGV--VFQK--DALLPWLNVLDNVAFGLRLRGVP-KAERRARAEELLALVGLA-DFARRRIWQLSGGMRQR 142

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 549799341 473 IAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHD 524
Cdd:COG4525  143 VGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHS 194
cbiO PRK13637
energy-coupling factor transporter ATPase;
340-555 5.03e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 105.13  E-value: 5.03e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKlDKTTLRTMRRSVQMIFQDPFASLdprm 419
Cdd:PRK13637  22 ALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITD-KKVKLSDIRKKVGLVFQYPEYQL---- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 420 svgtaiMEPFIEH-------RLG-TKQQAREKAADLLEKVGLSPDMMR-RFPHEFSGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:PRK13637  97 ------FEETIEKdiafgpiNLGlSEEEIENRVKRAMNIVGLDYEDYKdKSPFELSGGQKRRVAIAGVVAMEPKILILDE 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 491 AVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDN 555
Cdd:PRK13637 171 PTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKE 235
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
5-257 5.87e-25

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 106.96  E-value: 5.87e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   5 ATSMEQTGgSVSPVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVM 84
Cdd:PRK09452   2 KKLNKQPS-SLSPLVELRGISKSF----DGKEVISNLDLTINNGEFLTLLGPSGCGKT----TVLRLIAGFETPDSGRIM 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  85 LGGRDLLALPEEEmrkvrgKDISMIFQEpmTSLNPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRfdd 164
Cdd:PRK09452  73 LDGQDITHVPAEN------RHVNTVFQS--YALFPHMTVFENVAFGLRM-QKTPAAEITPRVMEALRMVQLEEFAQR--- 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 165 YPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFR 244
Cdd:PRK09452 141 KPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRD 220

                        250
                 ....*....|...
gi 549799341 245 GDVVETGTTDDIF 257
Cdd:PRK09452 221 GRIEQDGTPREIY 233
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 19-250 6.40e-25

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 101.35  E-value: 6.40e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdGGWKsVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEM 98
Cdd:cd03216    1 LELRGITKRF---GGVK-ALDGVSLSVRRGEVHALLGENGAGKS----TLMKILSGLYKPDSGEILVDGKEVSFASPRDA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKvRGkdISMIfqepmtslnpifpigkqiaealtvhqdisssaakaevirllekvripnaknrfddypHQFSGGMRQRVM 178
Cdd:cd03216   73 RR-AG--IAMV---------------------------------------------------------YQLSVGERQMVE 92

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVET 250
Cdd:cd03216   93 IARALARNARLLILDEPTAALTPAEVERLFKVIRRLR-AQGVAVIFISHRLDEVFEIADRVTVLRDGRVVGT 163
cbiO PRK13641
energy-coupling factor transporter ATPase;
344-571 7.49e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 104.91  E-value: 7.49e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEV-LKLDKTTLRTMRRSVQMIFQDPFASLDPRmSVG 422
Cdd:PRK13641  26 ISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHItPETGNKNLKKLRKKVSLVFQFPEAQLFEN-TVL 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 423 TAIMepFIEHRLG-TKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKA 501
Cdd:PRK13641 105 KDVE--FGPKNFGfSEDEAKEKALKWLKKVGLSEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRK 182

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 502 QVCNLLLDLQQNLNLAFLfISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQhpYTKKLMSAVPVP 571
Cdd:PRK13641 183 EMMQLFKDYQKAGHTVIL-VTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDKE--WLKKHYLDEPAT 249
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 19-252 7.69e-25

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 102.96  E-value: 7.69e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFRVDGGWksVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDkktsRIEGKVMLGGRDLLALPEEEM 98
Cdd:cd03244    3 IEFKNVSLRYRPNLPP--VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVE----LSSGSILIDGVDISKIGLHDL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RkvrgKDISMIFQEPMT-------SLNPifpigkqiaeaLTVHQDisssaakAEVIRLLEKVRIpnaKNRFDDYPHQ--- 168
Cdd:cd03244   77 R----SRISIIPQDPVLfsgtirsNLDP-----------FGEYSD-------EELWQALERVGL---KEFVESLPGGldt 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 --------FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTlqEEEGMSVLFITHDMGVVAEvSDRTI 240
Cdd:cd03244  132 vveeggenLSVGQRQLLCLARALLRKSKILVLDEATASVDPETDALIQKTIRE--AFKDCTVLTIAHRLDTIID-SDRIL 208

                        250
                 ....*....|..
gi 549799341 241 VMFRGDVVETGT 252
Cdd:cd03244  209 VLDKGRVVEFDS 220
CP_lyasePhnL TIGR02324
phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P ...
 19-238 9.89e-25

phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated C-P lysase complex. This protein (PhnL) and the adjacent-encoded PhnK (TIGR02323) resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this C-P lyase complex rather than part of a transporter per se.


Pssm-ID: 131377 [Multi-domain]  Cd Length: 224  Bit Score: 102.85  E-value: 9.89e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   19 LSVQNLTTSF---RVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMR--LLDKKT--SRIEGKVMlggrDLL 91
Cdd:TIGR02324   2 LEVEDLSKTFtlhQQGGVRLPVLKNVSLTVNAGECVALSGPSGAGKSTLLKSLYAnyLPDSGRilVRHEGAWV----DLA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   92 ALPEEEMRKVRGKDISMIFQepMTSLNPIFPIGKQIAEALtVHQDISSSAAKAEVIRLLEKVRIPnaKNRFDDYPHQFSG 171
Cdd:TIGR02324  78 QASPREVLEVRRKTIGYVSQ--FLRVIPRVSALEVVAEPL-LERGVPREAARARARELLARLNIP--ERLWHLPPATFSG 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341  172 GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDR 238
Cdd:TIGR02324 153 GEQQRVNIARGFIADYPILLLDEPTASLDAANRQVVVELIAEAK-ARGAALIGIFHDEEVRELVADR 218
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
333-556 1.02e-24

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 106.08  E-value: 1.02e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 333 RKS--GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldkTTLRTMRRSVQMIFQD 410
Cdd:PRK11650  10 RKSydGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVV-----NELEPADRDIAMVFQN 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 411 pFAsLDPRMSV-----------GTAIMEpfIEHRLgtkqqarEKAADLLEkvgLSPdMMRRFPHEFSGGQRQRIAIARSL 479
Cdd:PRK11650  85 -YA-LYPHMSVrenmayglkirGMPKAE--IEERV-------AEAARILE---LEP-LLDRKPRELSGGQRQRVAMGRAI 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 480 MLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMavVE--RVSHRVAVMYLGEIVEIGPRAAVFDNP 556
Cdd:PRK11650 150 VREPAVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQ--VEamTLADRVVVMNGGVAEQIGTPVEVYEKP 226
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
340-569 1.22e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 104.01  E-value: 1.22e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLklDKTTLRTMRRSVQMIFQDPFASLdprm 419
Cdd:PRK13633  25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTS--DEENLWDIRNKAGMVFQNPDNQI---- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 420 sVGTAIME--PFIEHRLGTKQ-QAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:PRK13633  99 -VATIVEEdvAFGPENLGIPPeEIRERVDESLKKVGMY-EYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLD 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 497 VSIKAQVCNLLLDLQQNLNLAFLFISHDM-AVVErvSHRVAVMYLGEIVEIGPRAAVFdnPQHPYTKKLMSAVP 569
Cdd:PRK13633 177 PSGRREVVNTIKELNKKYGITIILITHYMeEAVE--ADRIIVMDSGKVVMEGTPKEIF--KEVEMMKKIGLDVP 246
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 18-259 1.69e-24

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 103.73  E-value: 1.69e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVDggwKSVVRNMSFeIAPRET-VAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRdllALPEE 96
Cdd:PRK13652   3 LIETRDLCYSYSGS---KEALNNINF-IAPRNSrIAVIGPNGAGKS----TLFRHFNGILKPTSGSVLIRGE---PITKE 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  97 EMRKVRgKDISMIFQEPMtslNPIFpigkqiaeALTVHQDIS----SSAAKAEVI--RLLEKVRIPNAKNRFDDYPHQFS 170
Cdd:PRK13652  72 NIREVR-KFVGLVFQNPD---DQIF--------SPTVEQDIAfgpiNLGLDEETVahRVSSALHMLGLEELRDRVPHHLS 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 171 GGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVET 250
Cdd:PRK13652 140 GGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAY 219


                 ....*....
gi 549799341 251 GTTDDIFHR 259
Cdd:PRK13652 220 GTVEEIFLQ 228
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 27-260 1.78e-24

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 103.29  E-value: 1.78e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  27 SFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTsriEGKVMLGGrdlLALPEEEMRKVRgKDI 106
Cdd:PRK13648  14 SFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKS-TIAKLMIGIEKVK---SGEIFYNN---QAITDDNFEKLR-KHI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 107 SMIFQEPMTSLnpIFPIGK-QIAEALTVHQdISSSAAKAEVIRLLEKVripNAKNRFDDYPHQFSGGMRQRVMIAMALAS 185
Cdd:PRK13648  86 GIVFQNPDNQF--VGSIVKyDVAFGLENHA-VPYDEMHRRVSEALKQV---DMLERADYEPNALSGGQKQRVAIAGVLAL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 186 KPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEvSDRTIVMFRGDVVETGTTDDIFHRG 260
Cdd:PRK13648 160 NPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFDHA 233
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 313-566 1.85e-24

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 102.93  E-value: 1.85e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLttrfdirSGLFGRKSgavhAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRL--IEP---TSGDVMLDGY 387
Cdd:PRK14239   4 PILQVSDL-------SVYYNKKK----ALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndLNPevtITGSIVYNGH 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 388 EVLKLDKTTLRtMRRSVQMIFQ--DPFA-SLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVglsPDMMRRFPHE 464
Cdd:PRK14239  73 NIYSPRTDTVD-LRKEIGMVFQqpNPFPmSIYENVVYGLRLKGIKDKQVLDEAVEKSLKGASIWDEV---KDRLHDSALG 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 465 FSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIV 544
Cdd:PRK14239 149 LSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKI--EETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDLI 226

                        250       260
                 ....*....|....*....|..
gi 549799341 545 EIGPRAAVFDNPQHPYTKKLMS 566
Cdd:PRK14239 227 EYNDTKQMFMNPKHKETEDYIS 248
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 37-255 2.43e-24

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 101.85  E-value: 2.43e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  37 VVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPeeeMRKVRGKdISMIFQEPMts 116
Cdd:cd03249   18 ILKGLSLTIPPGKTVALVGSSGCGKS----TVVSLLERFYDPTSGEILLDGVDIRDLN---LRWLRSQ-IGLVSQEPV-- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 117 lnpIFPIgkqiaealTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQF-----------SGGMRQRVMIAMALAS 185
Cdd:cd03249   88 ---LFDG--------TIAENIRYGKPDATDEEVEEAAKKANIHDFIMSLPDGYdtlvgergsqlSGGQKQRIAIARALLR 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 186 KPKLLIADEPTTALDVTIQGQI---LDLIKtlqeeEGMSVLFITHDMGVVAEvSDRTIVMFRGDVVETGTTDD 255
Cdd:cd03249  157 NPKILLLDEATSALDAESEKLVqeaLDRAM-----KGRTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQGTHDE 223
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 16-256 2.44e-24

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 101.98  E-value: 2.44e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLLALPE 95
Cdd:COG0410    1 MPMLEVENLHAGY----GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPR----SGSIRFDGEDITGLPP 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKvRGkdISMIfqepmtslnpifPIGKQIAEALTVHQDI----SSSAAKAEVIRLLEKV--RIPNAKNRFDDYPHQF 169
Cdd:COG0410   73 HRIAR-LG--IGYV------------PEGRRIFPSLTVEENLllgaYARRDRAEVRADLERVyeLFPRLKERRRQRAGTL 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVE 249
Cdd:COG0410  138 SGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLN-REGVTILLVEQNARFALEIADRAYVLERGRIVL 216


                 ....*..
gi 549799341 250 TGTTDDI 256
Cdd:COG0410  217 EGTAAEL 223
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 35-252 2.57e-24

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 101.92  E-value: 2.57e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  35 KSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEMRKVrgkdISMIFQEpm 114
Cdd:cd03253   14 RPVLKDVSFTIPAGKKVAIVGPSGSGKS----TILRLLFRFYDVSSGSILIDGQDIREVTLDSLRRA----IGVVPQD-- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 115 tslNPIF--PIGKQIAEAltvhqdiSSSAAKAEVIRLLEKVRIPNAKNRFDD-YPHQ-------FSGGMRQRVMIAMALA 184
Cdd:cd03253   84 ---TVLFndTIGYNIRYG-------RPDATDEEVIEAAKAAQIHDKIMRFPDgYDTIvgerglkLSGGEKQRVAIARAIL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341 185 SKPKLLIADEPTTALDVT----IQGQILDLIKtlqeeeGMSVLFITHDMGVVAEvSDRTIVMFRGDVVETGT 252
Cdd:cd03253  154 KNPPILLLDEATSALDTHtereIQAALRDVSK------GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGT 218
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 19-251 2.85e-24

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 100.75  E-value: 2.85e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEM 98
Cdd:cd03268    1 LKTNDLTKTY----GKKRVLDDISLHVKKGEIYGFLGPNGAGKT-TTMKIILGLIKPDS---GEITFDGKSYQKNIEALR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RkvrgkdISMIFQEPmtSLNPifpigkqiaeALTVHQDISSSAA-----KAEVIRLLEKVripNAKNRFDDYPHQFSGGM 173
Cdd:cd03268   73 R------IGALIEAP--GFYP----------NLTARENLRLLARllgirKKRIDEVLDVV---GLKDSAKKKVKGFSLGM 131

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 174 RQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:cd03268  132 KQRLGIALALLGNPDLLILDEPTNGLDPDGIKELRELILSLR-DQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 341-568 3.28e-24

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 102.87  E-value: 3.28e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSG-----DVMLDGYEVLklDKTTLRTMRRSVQMIFQDPfasl 415
Cdd:PRK14271  37 LDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGyrysgDVLLGGRSIF--NYRDVLEFRRRVGMLFQRP---- 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DP-RMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGL---SPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEA 491
Cdd:PRK14271 111 NPfPMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLwdaVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEP 190

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 492 VSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAV 568
Cdd:PRK14271 191 TSALDPTTTEKI--EEFIRSLADRLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAETARYVAGL 265
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 314-581 3.99e-24

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 103.39  E-value: 3.99e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFDirsglfGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVML-DGYEVLKL 392
Cdd:PRK13631  21 ILRVKNLYCVFD------EKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgDIYIGDKK 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 393 DKTT------------LRTMRRSVQMIFQDPFASLDpRMSVGTAIMepFIEHRLG-TKQQAREKAADLLEKVGLSPDMMR 459
Cdd:PRK13631  95 NNHElitnpyskkiknFKELRRRVSMVFQFPEYQLF-KDTIEKDIM--FGPVALGvKKSEAKKLAKFYLNKMGLDDSYLE 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 460 RFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLfISHDMAVVERVSHRVAVMY 539
Cdd:PRK13631 172 RSPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFV-ITHTMEHVLEVADEVIVMD 250

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 549799341 540 LGEIVEIGPRAAVFDNpQHPYTKKLMSAVPVPDPARRQIKRN 581
Cdd:PRK13631 251 KGKILKTGTPYEIFTD-QHIINSTSIQVPRVIQVINDLIKKD 291
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 314-552 4.52e-24

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 102.88  E-value: 4.52e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYevlKLD 393
Cdd:COG4152    1 MLELKGLTKRF-----------GDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGE---PLD 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 KTTLRTM------RrsvqmifqdpfaSLDPRMSVGTAIMepfiehRLG-----TKQQAREKAADLLEKVGLSPDMMRRFp 462
Cdd:COG4152   67 PEDRRRIgylpeeR------------GLYPKMKVGEQLV------YLArlkglSKAEAKRRADEWLERLGLGDRANKKV- 127

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 463 HEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDvSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGE 542
Cdd:COG4152  128 EELSKGNQQKVQLIAALLHDPELLILDEPFSGLD-PVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGR 206

                        250
                 ....*....|
gi 549799341 543 IVEIGPRAAV 552
Cdd:COG4152  207 KVLSGSVDEI 216
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 346-547 5.35e-24

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 100.32  E-value: 5.35e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  346 FDL--AEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyevlkLDKTTLRTMRRSVQMIFQDP--FASLDPRMSV 421
Cdd:TIGR01277  17 FDLnvADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVND-----QSHTGLAPYQRPVSMLFQENnlFAHLTVRQNI 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  422 GTAImEPFIehRLGTKQQarEKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKA 501
Cdd:TIGR01277  92 GLGL-HPGL--KLNAEQQ--EKVVDAAQQVGIA-DYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLRE 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 549799341  502 QVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:TIGR01277 166 EMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 40-251 5.69e-24

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 100.26  E-value: 5.69e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  40 NMSFE--IAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEmrkvrgKDISMIFQEpmtsl 117
Cdd:cd03298   14 PMHFDltFAQGEITAIVGPSGSGKS-TLLNLIAGFETPQS---GRVLINGVDVTAAPPAD------RPVSMLFQE----- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 118 NPIFPigkqiaeALTVHQDIS---------SSAAKAEVIRLLEKVRIPNAKNRFddyPHQFSGGMRQRVMIAMALASKPK 188
Cdd:cd03298   79 NNLFA-------HLTVEQNVGlglspglklTAEDRQAIEVALARVGLAGLEKRL---PGELSGGERQRVALARVLVRDKP 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 189 LLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:cd03298  149 VLLLDEPFAALDPALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 19-251 5.88e-24

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 100.52  E-value: 5.88e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTslsiMRLLDKKTSRIEGKVMLGGRDLLALPEEEM 98
Cdd:cd03266    2 ITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTT----LRMLAGLLEPDAGFATVDGFDVVKEPAEAR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVrgkdismifqepmtslnPIFPIGKQIAEALTVHQDI---------SSSAAKAEVIRLLEKVRIpnaKNRFDDYPHQF 169
Cdd:cd03266   78 RRL-----------------GFVSDSTGLYDRLTARENLeyfaglyglKGDELTARLEELADRLGM---EELLDRRVGGF 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVE 249
Cdd:cd03266  138 STGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLR-ALGKCILFSTHIMQEVERLCDRVVVLHRGRVVY 216


                 ..
gi 549799341 250 TG 251
Cdd:cd03266  217 EG 218
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 40-247 8.42e-24

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 99.79  E-value: 8.42e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  40 NMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEMRKVRGKdISMIFQEpmTSLNP 119
Cdd:cd03292   19 GINISISAGEFVFLVGPSGAGKS----TLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLRRK-IGVVFQD--FRLLP 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 120 IFPIGKQIAEALTVHQDISSSAAKaEVIRLLEKVRIpnaKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTAL 199
Cdd:cd03292   92 DRNVYENVAFALEVTGVPPREIRK-RVPAALELVGL---SHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNL 167

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 549799341 200 DVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDV 247
Cdd:cd03292  168 DPDTTWEIMNLLKKIN-KAGTTVVVATHAKELVDTTRHRVIALERGKL 214
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
42-256 9.63e-24

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 100.04  E-value: 9.63e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  42 SFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEmrkvrgKDISMIFQEpmtslNPIF 121
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKS-TLLNLIAGFLTPAS---GSLTLNGQDHTTTPPSR------RPVSMLFQE-----NNLF 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 122 PigkqiaeALTVHQDIS---------SSAAKAEVIRLLEKVRIPNAKNRFddyPHQFSGGMRQRVMIAMALASKPKLLIA 192
Cdd:PRK10771  84 S-------HLTVAQNIGlglnpglklNAAQREKLHAIARQMGIEDLLARL---PGQLSGGQRQRVALARCLVREQPILLL 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 193 DEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:PRK10771 154 DEPFSALDPALRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDEL 217
cbiO PRK13646
energy-coupling factor transporter ATPase;
38-257 1.09e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 101.39  E-value: 1.09e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  38 VRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTsrieGKVMLGGRDLLA-LPEEEMRKVRgKDISMIFQEPMTs 116
Cdd:PRK13646  23 IHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTT----GTVTVDDITITHkTKDKYIRPVR-KRIGMVFQFPES- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 117 lnpifpigkQIAEAlTVHQDI---------SSSAAKAEVIRLLEKVRIPnaKNRFDDYPHQFSGGMRQRVMIAMALASKP 187
Cdd:PRK13646  97 ---------QLFED-TVEREIifgpknfkmNLDEVKNYAHRLLMDLGFS--RDVMSQSPFQMSGGQMRKIAIVSILAMNP 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 188 KLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIF 257
Cdd:PRK13646 165 DIIVLDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELF 234
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
17-228 1.29e-23

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 100.71  E-value: 1.29e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLAlPee 96
Cdd:COG4525    2 SMLTVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKT-TLLNLIAGFLAPSS---GEITLDGVPVTG-P-- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  97 emrkvrGKDISMIFQEpmTSLNPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRFddyPHQFSGGMRQR 176
Cdd:COG4525   75 ------GADRGVVFQK--DALLPWLNVLDNVAFGLRL-RGVPKAERRARAEELLALVGLADFARRR---IWQLSGGMRQR 142

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 549799341 177 VMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHD 228
Cdd:COG4525  143 VGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHS 194
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
340-547 1.45e-23

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 105.04  E-value: 1.45e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLdktTLRTMRRSVQMIFQDP--FA-SLD 416
Cdd:PRK13657 350 GVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTV---TRASLRRNIAVVFQDAglFNrSIE 426

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 417 PRMSVG--TAIMEpfiEHRLGTKqqaREKAADLLEKVGLSPDMM-----RRFphefSGGQRQRIAIARSLMLDPKVIVAD 489
Cdd:PRK13657 427 DNIRVGrpDATDE---EMRAAAE---RAQAHDFIERKPDGYDTVvgergRQL----SGGERQRLAIARALLKDPPILILD 496

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 490 EAVSALDVSIKAQVcNLLLDLQQNLNLAFLfISHDMAVVeRVSHRVAVMYLGEIVEIG 547
Cdd:PRK13657 497 EATSALDVETEAKV-KAALDELMKGRTTFI-IAHRLSTV-RNADRILVFDNGRVVESG 551
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 27-268 1.62e-23

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 99.48  E-value: 1.62e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  27 SFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEMRKvrgkDI 106
Cdd:cd03252    7 RFRYKPDGPVILDNISLRIKPGEVVGIVGRSGSGKS----TLTKLIQRFYVPENGRVLVDGHDLALADPAWLRR----QV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 107 SMIFQEpmtslNPIFpigkqiaeALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQF-----------SGGMRQ 175
Cdd:cd03252   79 GVVLQE-----NVLF--------NRSIRDNIALADPGMSMERVIEAAKLAGAHDFISELPEGYdtivgeqgaglSGGQRQ 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeeEGMSVLFITHDMGVVaEVSDRTIVMFRGDVVETGTTDD 255
Cdd:cd03252  146 RIAIARALIHNPRILIFDEATSALDYESEHAIMRNMHDIC--AGRTVIIIAHRLSTV-KNADRIIVMEKGRIVEQGSHDE 222

                        250
                 ....*....|....
gi 549799341 256 IF-HRGRHPYTRAL 268
Cdd:cd03252  223 LLaENGLYAYLYQL 236
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 42-264 1.87e-23

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 102.11  E-value: 1.87e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   42 SFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDL------LALPEEEMRkvrgkdISMIFQEpmT 115
Cdd:TIGR02142  17 DFTLPGQGVTAIFGRSGSGKT----TLIRLIAGLTRPDEGEIVLNGRTLfdsrkgIFLPPEKRR------IGYVFQE--A 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  116 SLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLekvripNAKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEP 195
Cdd:TIGR02142  85 RLFPHLSVRGNLRYGMKRARPSERRISFERVIELL------GIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEP 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341  196 TTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRGRHPY 264
Cdd:TIGR02142 159 LAALDDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPW 227
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 18-257 1.91e-23

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 101.47  E-value: 1.91e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSF---RVDGGWksVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIEGKVMLGGRDLLALP 94
Cdd:PRK13631  21 ILRVKNLYCVFdekQENELV--ALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYIGDKKNNHE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 EEEM---RKVRG-----KDISMIFQEPMTSLnpiFP--IGKQIA---EALTVHQDISSSAAKAEVIRLlekvripNAKNR 161
Cdd:PRK13631  99 LITNpysKKIKNfkelrRRVSMVFQFPEYQL---FKdtIEKDIMfgpVALGVKKSEAKKLAKFYLNKM-------GLDDS 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 162 F-DDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTlQEEEGMSVLFITHDMGVVAEVSDRTI 240
Cdd:PRK13631 169 YlERSPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILD-AKANNKTVFVITHTMEHVLEVADEVI 247

                        250
                 ....*....|....*..
gi 549799341 241 VMFRGDVVETGTTDDIF 257
Cdd:PRK13631 248 VMDKGKILKTGTPYEIF 264
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 315-555 2.05e-23

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 99.05  E-value: 2.05e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLdk 394
Cdd:cd03224    1 LEVENLNAGY-----------GKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGL-- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 TTLRTMRRSVQMIFQDPfaSLDPRMSVgtaiMEPFiehRLGTKQQAREKAADLLEKV-GLSP---DMMRRFPHEFSGGQR 470
Cdd:cd03224   68 PPHERARAGIGYVPEGR--RIFPELTV----EENL---LLGAYARRRAKRKARLERVyELFPrlkERRKQLAGTLSGGEQ 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 471 QRIAIARSLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRA 550
Cdd:cd03224  139 QMLAIARALMSRPKLLLLDEPSEGLAPKIVEEI-FEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAA 217


                 ....*
gi 549799341 551 AVFDN 555
Cdd:cd03224  218 ELLAD 222
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 17-266 2.18e-23

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 100.11  E-value: 2.18e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFRVdggwKSVVRNMSFEIAPRETVAIVGESGSGKS--VTSLSIMRLLDKKTsRIEGKVMLGGRDLLAlP 94
Cdd:PRK14258   6 PAIKVNNLSFYYDT----QKILEGVSMEIYQSKVTAIIGPSGCGKStfLKCLNRMNELESEV-RVEGRVEFFNQNIYE-R 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 EEEMRKVRgKDISMIFQEPmtslnPIFPIGKQIAEALTVH----------QDISSSAAKAEviRLLEKVripnaKNRFDD 164
Cdd:PRK14258  80 RVNLNRLR-RQVSMVHPKP-----NLFPMSVYDNVAYGVKivgwrpkleiDDIVESALKDA--DLWDEI-----KHKIHK 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 165 YPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTiVMFR 244
Cdd:PRK14258 147 SALDLSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFT-AFFK 225

                        250       260
                 ....*....|....*....|....*...
gi 549799341 245 GD------VVETGTTDDIFHRGRHPYTR 266
Cdd:PRK14258 226 GNenrigqLVEFGLTKKIFNSPHDSRTR 253
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 19-248 2.56e-23

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 99.78  E-value: 2.56e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFRVDGGW-KSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMR---LLDkktsriEGKVMLGGRDLLALP 94
Cdd:COG1101    2 LELKNLSKTFNPGTVNeKRALDGLNLTIEEGDFVTVIGSNGAGKS-TLLNAIAgslPPD------SGSILIDGKDVTKLP 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 EEEmrkvRGKDISMIFQEPM--TslnpifpigkqiAEALTVHQDIS---------------SSAAKAEVIRLLEKVRIpN 157
Cdd:COG1101   75 EYK----RAKYIGRVFQDPMmgT------------APSMTIEENLAlayrrgkrrglrrglTKKRRELFRELLATLGL-G 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 158 AKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSD 237
Cdd:COG1101  138 LENRLDTKVGLLSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGN 217

                        250
                 ....*....|.
gi 549799341 238 RTIVMFRGDVV 248
Cdd:COG1101  218 RLIMMHEGRII 228
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
345-551 3.14e-23

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 98.50  E-value: 3.14e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 345 SFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyevlkLDKTTLRTMRRSVQMIFQDP--FASLDPRMSVG 422
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNG-----QDHTTTPPSRRPVSMLFQENnlFSHLTVAQNIG 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 423 TAiMEPFIehRLGTKQqaREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKA- 501
Cdd:PRK10771  94 LG-LNPGL--KLNAAQ--REKLHAIARQMGIE-DLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQe 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 502 ------QVCnllldlqQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAA 551
Cdd:PRK10771 168 mltlvsQVC-------QERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDE 216
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 19-251 4.46e-23

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 97.65  E-value: 4.46e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTtsFRVDGGWksVVRNMSFEIaPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEeM 98
Cdd:cd03264    1 LQLENLT--KRYGKKR--ALDGVSLTL-GPGMYGLLGPNGAGKT----TLMRILATLTPPSSGTIRIDGQDVLKQPQK-L 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVrgkdISMIFQEPMTSlnPIFPIGKQIAEALTVHqDISSSAAKAEVIRLLEKVripNAKNRFDDYPHQFSGGMRQRVM 178
Cdd:cd03264   71 RRR----IGYLPQEFGVY--PNFTVREFLDYIAWLK-GIPSKEVKARVDEVLELV---NLGDRAKKKIGSLSGGMRRRVG 140

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEgmSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:cd03264  141 IAQALVGDPSILIVDEPTAGLDPEERIRFRNLLSELGEDR--IVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 18-257 4.96e-23

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 99.38  E-value: 4.96e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRvDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLlALPEEE 97
Cdd:PRK13639   1 ILETRDLKYSYP-DG--TEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPT----SGEVLIKGEPI-KYDKKS 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 MRKVRgKDISMIFQEPMtslNPIFpigkqiaeALTVHQDI---------SSSAAKAEVIRLLEKVRIPNAKNRfddYPHQ 168
Cdd:PRK13639  73 LLEVR-KTVGIVFQNPD---DQLF--------APTVEEDVafgplnlglSKEEVEKRVKEALKAVGMEGFENK---PPHH 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:PRK13639 138 LSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLN-KEGITIIISTHDVDLVPVYADKVYVMSDGKII 216


                 ....*....
gi 549799341 249 ETGTTDDIF 257
Cdd:PRK13639 217 KEGTPKEVF 225
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 19-247 5.43e-23

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 96.13  E-value: 5.43e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLttSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEM 98
Cdd:cd03246    1 LEVENV--SFRYPGAEPPVLRNVSFSIEPGESLAIIGPSGSGKS----TLARLILGLLRPTSGRVRLDGADISQWDPNEL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGkdismifqepmtslnpifpigkqiaealTVHQDIS-SSAAKAEVIrllekvripnaknrfddyphqFSGGMRQRV 177
Cdd:cd03246   75 GDHVG----------------------------YLPQDDElFSGSIAENI---------------------LSGGQRQRL 105

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVsDRTIVMFRGDV 247
Cdd:cd03246  106 GLARALYGNPRILVLDEPNSHLDVEGERALNQAIAALK-AAGATRIVIAHRPETLASA-DRILVLEDGRV 173
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 313-562 6.85e-23

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 98.57  E-value: 6.85e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFDIRSglfgrksgavhAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEpTSGDVMLDG------ 386
Cdd:PRK14258   6 PAIKVNNLSFYYDTQK-----------ILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNE-LESEVRVEGrveffn 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 387 ---YEvlklDKTTLRTMRRSVQMIFQDPfaSLDPrMSV------GTAIM--EPFIEhrLGTKQQAREKAADLLEKVglsP 455
Cdd:PRK14258  74 qniYE----RRVNLNRLRRQVSMVHPKP--NLFP-MSVydnvayGVKIVgwRPKLE--IDDIVESALKDADLWDEI---K 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 456 DMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRV 535
Cdd:PRK14258 142 HKIHKSALDLSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFT 221

                        250       260       270
                 ....*....|....*....|....*....|..
gi 549799341 536 AVMY-----LGEIVEIGPRAAVFDNPQHPYTK 562
Cdd:PRK14258 222 AFFKgnenrIGQLVEFGLTKKIFNSPHDSRTR 253
cbiO PRK13640
energy-coupling factor transporter ATPase;
35-257 7.21e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 99.10  E-value: 7.21e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  35 KSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLL---DKKTSRIegkVMLGgrdlLALPEEEMRKVRGKdISMIFQ 111
Cdd:PRK13640  20 KPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLlpdDNPNSKI---TVDG----ITLTAKTVWDIREK-VGIVFQ 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 112 EPmtslnpifpiGKQIAEAlTVHQDIS-----SSAAKAEVIRLLEKVRIPNAKNRF-DDYPHQFSGGMRQRVMIAMALAS 185
Cdd:PRK13640  92 NP----------DNQFVGA-TVGDDVAfglenRAVPRPEMIKIVRDVLADVGMLDYiDSEPANLSGGQKQRVAIAGILAV 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341 186 KPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGvVAEVSDRTIVMFRGDVVETGTTDDIF 257
Cdd:PRK13640 161 EPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDID-EANMADQVLVLDDGKLLAQGSPVEIF 231
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 26-260 8.23e-23

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 97.30  E-value: 8.23e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  26 TSFRVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLLALPEEEMRKVrgkd 105
Cdd:cd03254    8 VNFSYDEK-KPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQ----KGQILIDGIDIRDISRKSLRSM---- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 106 ISMIFQEPMtslnpIFPigKQIAEALTVHQDIsssAAKAEVIRLLEKVR----IPNAKNRFDDYP----HQFSGGMRQRV 177
Cdd:cd03254   79 IGVVLQDTF-----LFS--GTIMENIRLGRPN---ATDEEVIEAAKEAGahdfIMKLPNGYDTVLgengGNLSQGERQLL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeeEGMSVLFITHDMGVVAEvSDRTIVMFRGDVVETGTTDDIF 257
Cdd:cd03254  149 AIARAMLRDPKILILDEATSNIDTETEKLIQEALEKLM--KGRTSIIIAHRLSTIKN-ADKILVLDDGKIIEEGTHDELL 225


                 ...
gi 549799341 258 HRG 260
Cdd:cd03254  226 AKK 228
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 294-497 9.77e-23

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 102.05  E-value: 9.77e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  294 TGESQPVADV---KDTVSGGRTPILSVKDLTTRFDirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRS 370
Cdd:TIGR02868 311 LDAAGPVAEGsapAAGAVGLGKPTLELRDLSAGYP----------GAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLAT 380

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  371 ITRLIEPTSGDVMLDGYEVLKLDKTTLrtmRRSVQMIFQDP--FASldprmSVGTAImepfiehRLGTKQQAREKAADLL 448
Cdd:TIGR02868 381 LAGLLDPLQGEVTLDGVPVSSLDQDEV---RRRVSVCAQDAhlFDT-----TVRENL-------RLARPDATDEELWAAL 445

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  449 EKVGLSpDMMRRFPH-----------EFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:TIGR02868 446 ERVGLA-DWLRALPDgldtvlgeggaRLSGGERQRLALARALLADAPILLLDEPTEHLDA 504
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 312-557 1.01e-22

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 97.36  E-value: 1.01e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLK 391
Cdd:COG0410    1 MPMLEVENLHAGY-----------GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITG 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 392 LDktTLRTMRRSV------QMIFqdpfasldPRMSVgtaimepfIEH-RLGTKQQ-AREKAADLLEKVglspdmMRRFP- 462
Cdd:COG0410   70 LP--PHRIARLGIgyvpegRRIF--------PSLTV--------EENlLLGAYARrDRAEVRADLERV------YELFPr 125

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 463 -HEF--------SGGQRQRIAIARSLMLDPKVIVADEA-----------VSALDVSIKAQvcnllldlqqnlNLAFLFIS 522
Cdd:COG0410  126 lKERrrqragtlSGGEQQMLAIGRALMSRPKLLLLDEPslglapliveeIFEIIRRLNRE------------GVTILLVE 193

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 549799341 523 HDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQ 557
Cdd:COG0410  194 QNARFALEIADRAYVLERGRIVLEGTAAELLADPE 228
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
336-544 1.04e-22

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 96.87  E-value: 1.04e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQDPFASL 415
Cdd:PRK10908  13 GGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQDHHLLM 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAImePFIEHRlGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSAL 495
Cdd:PRK10908  93 DRTVYDNVAI--PLIIAG-ASGDDIRRRVSAALDKVGLL-DKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNL 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 549799341 496 DVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIV 544
Cdd:PRK10908 169 DDALSEGI-LRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGHLH 216
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 340-548 1.08e-22

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 102.49  E-value: 1.08e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLdktTLRTMRRSVQMIFQDPFASLDPRM 419
Cdd:TIGR02203 347 ALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADY---TLASLRRQVALVSQDVVLFNDTIA 423

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  420 -SVGTAIMEPFIEHRLgtkqQAREKAADLLEKVGLSPDMMRRFPHE----FSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:TIGR02203 424 nNIAYGRTEQADRAEI----ERALAAAYAQDFVDKLPLGLDTPIGEngvlLSGGQRQRLAIARALLKDAPILILDEATSA 499

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 549799341  495 LDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEIVEIGP 548
Cdd:TIGR02203 500 LDNESERLV--QAALERLMQGRTTLVIAHRLSTIEK-ADRIVVMDDGRIVERGT 550
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 339-549 1.35e-22

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 96.53  E-value: 1.35e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 339 HAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMrrsVQMIFQDPFasldpr 418
Cdd:cd03254   17 PVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSM---IGVVLQDTF------ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 419 MSVGTaIMEPFiehRLGTKQQAREKAADLLEKVGLSpDMMRRFP-----------HEFSGGQRQRIAIARSLMLDPKVIV 487
Cdd:cd03254   88 LFSGT-IMENI---RLGRPNATDEEVIEAAKEAGAH-DFIMKLPngydtvlgengGNLSQGERQLLAIARAMLRDPKILI 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341 488 ADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEIVEIGPR 549
Cdd:cd03254  163 LDEATSNIDTETEKLI--QEALEKLMKGRTSIIIAHRLSTIKN-ADKILVLDDGKIIEEGTH 221
type_I_sec_HlyB TIGR01846
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ...
 344-547 1.50e-22

type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273831 [Multi-domain]  Cd Length: 694  Bit Score: 102.51  E-value: 1.50e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRtmrRSVQMIFQDPF----------A 413
Cdd:TIGR01846 476 LNLDIKPGEFIGIVGPSGSGKSTLTKLLQRLYTPQHGQVLVDGVDLAIADPAWLR---RQMGVVLQENVlfsrsirdniA 552

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  414 SLDPRMSVGTAI-------MEPFI-EHRLGTKQQAREKAADLlekvglspdmmrrfphefSGGQRQRIAIARSLMLDPKV 485
Cdd:TIGR01846 553 LCNPGAPFEHVIhaaklagAHDFIsELPQGYNTEVGEKGANL------------------SGGQRQRIAIARALVGNPRI 614

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341  486 IVADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVeRVSHRVAVMYLGEIVEIG 547
Cdd:TIGR01846 615 LIFDEATSALDYESEALI--MRNMREICRGRTVIIIAHRLSTV-RACDRIIVLEKGQIAESG 673
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
16-248 1.88e-22

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 101.72  E-value: 1.88e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPE 95
Cdd:PRK10535   2 TALLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKS-TLMNILGCLDKPTS---GTYRVAGQDVATLDA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGKDISMIFQE--PMTSLNpifpiGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIpnaKNRFDDYPHQFSGGM 173
Cdd:PRK10535  78 DALAQLRREHFGFIFQRyhLLSHLT-----AAQNVEVPAVYAGLERKQRLLRAQELLQRLGL---EDRVEYQPSQLSGGQ 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 174 RQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEvSDRTIVMFRGDVV 248
Cdd:PRK10535 150 QQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLR-DRGHTVIIVTHDPQVAAQ-AERVIEIRDGEIV 222
MsbA_rel TIGR02204
ABC transporter, permease/ATP-binding protein; This protein is related to a Proteobacterial ...
 340-553 2.28e-22

ABC transporter, permease/ATP-binding protein; This protein is related to a Proteobacterial ATP transporter that exports lipid A and to eukaryotic P-glycoproteins.


Pssm-ID: 131259 [Multi-domain]  Cd Length: 576  Bit Score: 101.32  E-value: 2.28e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRtmrRSVQMIFQDP--FAsldp 417
Cdd:TIGR02204 355 ALDGLNLTVRPGETVALVGPSGAGKSTLFQLLLRFYDPQSGRILLDGVDLRQLDPAELR---ARMALVPQDPvlFA---- 427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  418 rmsvgTAIMEPFIEHRLGTKQQAREKAADLLEKVGLspdmMRRFPHEF-----------SGGQRQRIAIARSLMLDPKVI 486
Cdd:TIGR02204 428 -----ASVMENIRYGRPDATDEEVEAAARAAHAHEF----ISALPEGYdtylgergvtlSGGQRQRIAIARAILKDAPIL 498

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341  487 VADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEIVEIGPRAAVF 553
Cdd:TIGR02204 499 LLDEATSALDAESEQLV--QQALETLMKGRTTLIIAHRLATVLK-ADRIVVMDQGRIVAQGTHAELI 562
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 10-270 2.29e-22

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 97.16  E-value: 2.29e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  10 QTGGSVSPVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDK-KTSRIEGKVMLGGR 88
Cdd:PRK14243   2 STLNGTETVLRTENLNVYY----GSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLiPGFRVEGKVTFHGK 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  89 DLLAlPEEEMRKVRgKDISMIFQEPmtslNPiFPigKQIAEALTVHQDISssAAKAEVIRLLEK-----VRIPNAKNRFD 163
Cdd:PRK14243  78 NLYA-PDVDPVEVR-RRIGMVFQKP----NP-FP--KSIYDNIAYGARIN--GYKGDMDELVERslrqaALWDEVKDKLK 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 164 DYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEegMSVLFITHDMGVVAEVSDRTiVMF 243
Cdd:PRK14243 147 QSGLSLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQ--YTIIIVTHNMQQAARVSDMT-AFF 223

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 549799341 244 RGDVVETG----------TTDDIFHRGRHPYTRALLS 270
Cdd:PRK14243 224 NVELTEGGgrygylvefdRTEKIFNSPQQQATRDYVS 260
cbiO PRK13642
energy-coupling factor transporter ATPase;
314-565 3.31e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 97.09  E-value: 3.31e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFDirsglfgrKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYevlKLD 393
Cdd:PRK13642   4 ILEVENLVFKYE--------KESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGE---LLT 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 KTTLRTMRRSVQMIFQDPFASLdprmsVGtAIMEPFIEHRLGTKQQAREKAADLLEKVGLSPDMM---RRFPHEFSGGQR 470
Cdd:PRK13642  73 AENVWNLRRKIGMVFQNPDNQF-----VG-ATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLdfkTREPARLSGGQK 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 471 QRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEIVEIGPRA 550
Cdd:PRK13642 147 QRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPS 225

                        250       260
                 ....*....|....*....|...
gi 549799341 551 AVFDNPQH--------PYTKKLM 565
Cdd:PRK13642 226 ELFATSEDmveigldvPFSSNLM 248
cbiO PRK13649
energy-coupling factor transporter ATPase;
40-259 4.05e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 96.74  E-value: 4.05e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  40 NMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPE-EEMRKVRgKDISMIFQepmtsln 118
Cdd:PRK13649  25 DVNLTIEDGSYTAFIGHTGSGKS----TIMQLLNGLHVPTQGSVRVDDTLITSTSKnKDIKQIR-KKVGLVFQ------- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 119 piFPIGKQIAEalTVHQDIS-------SSAAKAEVIRLlEKVRIPN-AKNRFDDYPHQFSGGMRQRVMIAMALASKPKLL 190
Cdd:PRK13649  93 --FPESQLFEE--TVLKDVAfgpqnfgVSQEEAEALAR-EKLALVGiSESLFEKNPFELSGGQMRRVAIAGILAMEPKIL 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 191 IADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHR 259
Cdd:PRK13649 168 VLDEPTAGLDPKGRKELMTLFKKLH-QSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQD 235
cbiO PRK13642
energy-coupling factor transporter ATPase;
15-257 4.70e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 96.32  E-value: 4.70e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  15 VSPVLSVQNLTTSFRVDGGWKSVvRNMSFEIAPRETVAIVGESGSGKSVTSlsimRLLDKKTSRIEGKVMLGGRDLLAlp 94
Cdd:PRK13642   1 MNKILEVENLVFKYEKESDVNQL-NGVSFSITKGEWVSIIGQNGSGKSTTA----RLIDGLFEEFEGKVKIDGELLTA-- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 eEEMRKVRGKdISMIFQEPMTSLnpifpIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSGGMR 174
Cdd:PRK13642  74 -ENVWNLRRK-IGMVFQNPDNQF-----VGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQK 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 175 QRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEvSDRTIVMFRGDVVETGTTD 254
Cdd:PRK13642 147 QRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPS 225


                 ...
gi 549799341 255 DIF 257
Cdd:PRK13642 226 ELF 228
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 316-538 6.10e-22

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 94.52  E-value: 6.10e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 316 SVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKldkt 395
Cdd:cd03235    1 EVEDLTVSY-----------GGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEK---- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 396 tlrtMRRSVQMIFQdpFASLDPRM------SVGTAIMePFIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQ 469
Cdd:cd03235   66 ----ERKRIGYVPQ--RRSIDRDFpisvrdVVLMGLY-GHKGLFRRLSKADKAKVDEALERVGLS-ELADRQIGELSGGQ 137

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 470 RQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVM 538
Cdd:cd03235  138 QQRVLLARALVQDPDLLLLDEPFAGVDPKTQEDI-YELLRELRREGMTILVVTHDLGLVLEYFDRVLLL 205
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 17-256 6.82e-22

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 99.49  E-value: 6.82e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   17 PVLSVQNLTTSF-RVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIEGKVmlgGRDLLALPE 95
Cdd:TIGR03269 278 PIIKVRNVSKRYiSVDRGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRV---GDEWVDMTK 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   96 E-EMRKVRGKD-ISMIFQEpmTSLNPIFPIGKQIAEALTVhqDISSSAAKAEVIRLLEKVRIPN--AKNRFDDYPHQFSG 171
Cdd:TIGR03269 355 PgPDGRGRAKRyIGILHQE--YDLYPHRTVLDNLTEAIGL--ELPDELARMKAVITLKMVGFDEekAEEILDKYPDELSE 430

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  172 GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:TIGR03269 431 GERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIG 510


                  ....*
gi 549799341  252 TTDDI 256
Cdd:TIGR03269 511 DPEEI 515
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 344-548 6.87e-22

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 94.99  E-value: 6.87e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlklDKTTLRTMRRSVQMIFQDpfasldprmsvgT 423
Cdd:cd03253   20 VSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDI---REVTLDSLRRAIGVVPQD------------T 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 424 AIMEPFIEH--RLG----TKQQARE--KAADLLEKVglspdmmRRFPHEF-----------SGGQRQRIAIARSLMLDPK 484
Cdd:cd03253   85 VLFNDTIGYniRYGrpdaTDEEVIEaaKAAQIHDKI-------MRFPDGYdtivgerglklSGGEKQRVAIARAILKNPP 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 485 VIVADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEIVEIGP 548
Cdd:cd03253  158 ILLLDEATSALDTHTEREI--QAALRDVSKGRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGT 218
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
27-262 7.35e-22

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 99.65  E-value: 7.35e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  27 SFRVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTsrieGKVMLGGRDLLALPEEEMRKvrgkDI 106
Cdd:PRK13657 341 SFSYDNS-RQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQS----GRILIDGTDIRTVTRASLRR----NI 411

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 107 SMIFQEPMtslnpIFpiGKQIAEALTVHQdisSSAAKAEVIRLLEKVR----IPNAKNRFD----DYPHQFSGGMRQRVM 178
Cdd:PRK13657 412 AVVFQDAG-----LF--NRSIEDNIRVGR---PDATDEEMRAAAERAQahdfIERKPDGYDtvvgERGRQLSGGERQRLA 481

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeeEGMSVLFITHDMGVVAEvSDRTIVMFRGDVVETGTTDDIFH 258
Cdd:PRK13657 482 IARALLKDPPILILDEATSALDVETEAKVKAALDELM--KGRTTFIIAHRLSTVRN-ADRILVFDNGRVVESGSFDELVA 558


                 ....
gi 549799341 259 RGRH 262
Cdd:PRK13657 559 RGGR 562
cbiO PRK13641
energy-coupling factor transporter ATPase;
40-257 7.38e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 96.05  E-value: 7.38e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  40 NMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLA-LPEEEMRKVRgKDISMIFQEPMTsln 118
Cdd:PRK13641  25 NISFELEEGSFVALVGHTGSGKS----TLMQHFNALLKPSSGTITIAGYHITPeTGNKNLKKLR-KKVSLVFQFPEA--- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 119 pifpigkQIAEAlTVHQDI---------SSSAAKAEVIRLLEKVRIPnaKNRFDDYPHQFSGGMRQRVMIAMALASKPKL 189
Cdd:PRK13641  97 -------QLFEN-TVLKDVefgpknfgfSEDEAKEKALKWLKKVGLS--EDLISKSPFELSGGQMRRVAIAGVMAYEPEI 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 190 LIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIF 257
Cdd:PRK13641 167 LCLDEPAAGLDPEGRKEMMQLFKDYQ-KAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIF 233
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
15-546 8.10e-22

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 99.09  E-value: 8.10e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  15 VSPVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALP 94
Cdd:PRK09700   2 ATPYISMAGIGKSF----GPVHALKSVNLTVYPGEIHALLGENGAGKS----TLMKVLSGIHEPTKGTITINNINYNKLD 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 EEEMRKVrgkDISMIFQE-----PMTSLNPIFpIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIpnaKNRFDDYPHQF 169
Cdd:PRK09700  74 HKLAAQL---GIGIIYQElsvidELTVLENLY-IGRHLTKKVCGVNIIDWREMRVRAAMMLLRVGL---KVDLDEKVANL 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVE 249
Cdd:PRK09700 147 SISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLR-KEGTAIVYISHKLAEIRRICDRYTVMKDGSSVC 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 250 TGTTDDIFHRGrhpytrallsaVPKLgsMKERLLPARFPiidiktgesqpvADVKDTVSGGRTPILSVKDLTTRFDIRsg 329
Cdd:PRK09700 226 SGMVSDVSNDD-----------IVRL--MVGRELQNRFN------------AMKENVSNLAHETVFEVRNVTSRDRKK-- 278

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 330 lfgrksgavhaVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKldKTTLRTMRRSVQMIFQ 409
Cdd:PRK09700 279 -----------VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISP--RSPLDAVKKGMAYITE 345

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 410 D-------PFASLDPRMSVGTAIMEPFIEHRLGTKQQAREK--AADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLM 480
Cdd:PRK09700 346 SrrdngffPNFSIAQNMAISRSLKDGGYKGAMGLFHEVDEQrtAENQRELLALKCHSVNQNITELSGGNQQKVLISKWLC 425

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 481 LDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEI 546
Cdd:PRK09700 426 CCPEVIIFDEPTRGIDVGAKAEI-YKVMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQI 490
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 19-251 1.16e-21

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 93.36  E-value: 1.16e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSfrVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTsrIEGKVMLGGRDLLALPEEEm 98
Cdd:cd03217    1 LEIKDLHVS--VGG--KEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKYEV--TEGEILFKGEDITDLPPEE- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGkdISMIFQEPMtslnpifpigkqiaealtvhqDISSsaakaevIRLLEKVRIPNAKnrfddyphqFSGGMRQRVM 178
Cdd:cd03217   74 RARLG--IFLAFQYPP---------------------EIPG-------VKNADFLRYVNEG---------FSGGEKKRNE 114

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEV-SDRTIVMFRGDVVETG 251
Cdd:cd03217  115 ILQLLLLEPDLAILDEPDSGLDIDALRLVAEVINKLR-EEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSG 187
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 313-497 1.22e-21

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 93.31  E-value: 1.22e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFDIRSgLFgrksgavhavEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKL 392
Cdd:COG4133    1 MMLEAENLSCRRGERL-LF----------SGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 393 DkttlRTMRRSVQMIFQDPfaSLDPRMSVgtaimepfIEH-----RLGTKQQAREKAADLLEKVGLSPdMMRRFPHEFSG 467
Cdd:COG4133   70 R----EDYRRRLAYLGHAD--GLKPELTV--------RENlrfwaALYGLRADREAIDEALEAVGLAG-LADLPVRQLSA 134

                        170       180       190
                 ....*....|....*....|....*....|
gi 549799341 468 GQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:COG4133  135 GQKRRVALARLLLSPAPLWLLDEPFTALDA 164
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 340-557 1.30e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 95.47  E-value: 1.30e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLdGYEVLKLDK--TTLRTMRRSVQMIFQDPFASLdp 417
Cdd:PRK13634  22 ALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTI-GERVITAGKknKKLKPLRKKVGIVFQFPEHQL-- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 418 rmsvgtaiMEPFIEHRLG--------TKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVAD 489
Cdd:PRK13634  99 --------FEETVEKDICfgpmnfgvSEEDAKQKAREMIELVGLPEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLD 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 490 EAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQ 557
Cdd:PRK13634 171 EPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPD 238
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 311-524 1.85e-21

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 93.24  E-value: 1.85e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 311 RTPILSVKDLttrfdirsglfGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVL 390
Cdd:PRK10247   4 NSPLLQLQNV-----------GYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDIS 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 391 KLDKttlRTMRRSVQMIFQDPfasldprMSVGTAIMEPFIEHRLGTKQQAREKA-ADLLEKVGLSPDMMRRFPHEFSGGQ 469
Cdd:PRK10247  73 TLKP---EIYRQQVSYCAQTP-------TLFGDTVYDNLIFPWQIRNQQPDPAIfLDDLERFALPDTILTKNIAELSGGE 142

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 470 RQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHD 524
Cdd:PRK10247 143 KQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHD 197
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 17-245 1.86e-21

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 92.11  E-value: 1.86e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTtsfrvdggWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEE 96
Cdd:cd03215    3 PVLEVRGLS--------VKGAVRDVSFEVRAGEIVGIAGLVGNGQT----ELAEALFGLRPPASGEITLDGKPVTRRSPR 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  97 EMRKvrgKDISMIFQEPM-TSLNPIFPIgkqiaealtvhqdisssaakAEVIRLlekvripnaknrfddyPHQFSGGMRQ 175
Cdd:cd03215   71 DAIR---AGIAYVPEDRKrEGLVLDLSV--------------------AENIAL----------------SSLLSGGNQQ 111

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVtiqGQILDLIKTLQE--EEGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:cd03215  112 KVVLARWLARDPRVLILDEPTRGVDV---GAKAEIYRLIRElaDAGKAVLLISSELDELLGLCDRILVMYEG 180
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
336-557 2.11e-21

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 96.25  E-value: 2.11e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldkTTLRTMRRSVQMIFQD----P 411
Cdd:PRK11000  14 GDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRM-----NDVPPAERGVGMVFQSyalyP 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 412 FASLDPRMSVG---TAIMEPFIEHRLgtkqqarEKAADLLEKVGLspdmMRRFPHEFSGGQRQRIAIARSLMLDPKVIVA 488
Cdd:PRK11000  89 HLSVAENMSFGlklAGAKKEEINQRV-------NQVAEVLQLAHL----LDRKPKALSGGQRQRVAIGRTLVAEPSVFLL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 489 DEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQ 557
Cdd:PRK11000 158 DEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPA 226
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 16-242 2.33e-21

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 97.74  E-value: 2.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   16 SPVLSVQNLTTSFRvdGGWKsVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLLALPE 95
Cdd:TIGR02857 319 ASSLEFSGVSVAYP--GRRP-ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPT----EGSIAVNGVPLADADA 391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   96 eemrKVRGKDISMIFQEPMtslnpIFPigKQIAEALTVHQDISSSAAKAEVIRL-----LEKVRIPNAKNRFDDYPHQFS 170
Cdd:TIGR02857 392 ----DSWRDQIAWVPQHPF-----LFA--GTIAENIRLARPDASDAEIREALERagldeFVAALPQGLDTPIGEGGAGLS 460

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341  171 GGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeeEGMSVLFITHDMgVVAEVSDRTIVM 242
Cdd:TIGR02857 461 GGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALA--QGRTVLLVTHRL-ALAALADRIVVL 529
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 312-556 3.73e-21

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 93.13  E-value: 3.73e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLK 391
Cdd:PRK11300   3 QPLLSVSGLMMRF-----------GGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEG 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 392 LdkTTLRTMRRSVQMIFQDpfASLDPRMSVGTAIMepFIEHR----------LGTK------QQAREKAADLLEKVGLSp 455
Cdd:PRK11300  72 L--PGHQIARMGVVRTFQH--VRLFREMTVIENLL--VAQHQqlktglfsglLKTPafrraeSEALDRAATWLERVGLL- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 456 DMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRV 535
Cdd:PRK11300 145 EHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRI 224

                        250       260
                 ....*....|....*....|.
gi 549799341 536 AVMYLGEIVEIGPRAAVFDNP 556
Cdd:PRK11300 225 YVVNQGTPLANGTPEEIRNNP 245
cbiO PRK13645
energy-coupling factor transporter ATPase;
340-595 3.73e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 93.92  E-value: 3.73e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEV---LKLDKTtLRTMRRSVQMIFQDPFASLD 416
Cdd:PRK13645  26 ALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIpanLKKIKE-VKRLRKEIGLVFQFPEYQLF 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 417 PRMSVGTAIMEPFieHRLGTKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:PRK13645 105 QETIEKDIAFGPV--NLGENKQEAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLD 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 497 VSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNpqhpytKKLMSAVPVPDPARR 576
Cdd:PRK13645 183 PKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFSN------QELLTKIEIDPPKLY 256

                        250       260
                 ....*....|....*....|..
gi 549799341 577 QIK---RNMATDEIRSPIRPVD 595
Cdd:PRK13645 257 QLMyklKNKGIDLLNKNIRTIE 278
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 340-548 4.43e-21

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 92.17  E-value: 4.43e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDkttLRTMRRSVQMIFQDPF------- 412
Cdd:cd03244   19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIG---LHDLRSRISIIPQDPVlfsgtir 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 413 ASLDprmsvgtaimePFIEHRLGTKQQAREKAAdLLEKVGLSPDMMrRFPHE-----FSGGQRQRIAIARSLMLDPKVIV 487
Cdd:cd03244   96 SNLD-----------PFGEYSDEELWQALERVG-LKEFVESLPGGL-DTVVEeggenLSVGQRQLLCLARALLRKSKILV 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341 488 ADEAVSALDVSIKAQVcnllldlQQNLNLAF-----LFISHdmavveRV-----SHRVAVMYLGEIVEIGP 548
Cdd:cd03244  163 LDEATASVDPETDALI-------QKTIREAFkdctvLTIAH------RLdtiidSDRILVLDKGRVVEFDS 220
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 18-259 6.30e-21

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 94.00  E-value: 6.30e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRV----DGGWKSV-------------VRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrie 80
Cdd:COG4586    1 IIEVENLSKTYRVyekePGLKGALkglfrreyreveaVDDISFTIEPGEIVGFIGPNGAGKS-TTIKMLTGILVPTS--- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  81 GKVMLGGRDllalPEEEMRKVRgKDISMIF-QEpmTSLNPIFPIgkqiAEALTVHQ---DISSSAAK---AEVIRLLE-- 151
Cdd:COG4586   77 GEVRVLGYV----PFKRRKEFA-RRIGVVFgQR--SQLWWDLPA----IDSFRLLKaiyRIPDAEYKkrlDELVELLDlg 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 152 -----KVRipnaknrfddyphQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFIT 226
Cdd:COG4586  146 elldtPVR-------------QLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTS 212

                        250       260       270
                 ....*....|....*....|....*....|...
gi 549799341 227 HDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHR 259
Cdd:COG4586  213 HDMDDIEALCDRVIVIDHGRIIYDGSLEELKER 245
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 19-247 7.88e-21

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 92.43  E-value: 7.88e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTsrieGKVMLGGRDLLALPEEEM 98
Cdd:PRK11247  13 LLLNAVSKRY----GERTVLNQLDLHIPAGQFVAVVGRSGCGKS-TLLRLLAGLETPS----AGELLAGTAPLAEAREDT 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RkvrgkdisMIFQEpmTSLNPIFPIGKQIAEALTVHQdisssaaKAEVIRLLEKVRIpnaKNRFDDYPHQFSGGMRQRVM 178
Cdd:PRK11247  84 R--------LMFQD--ARLLPWKKVIDNVGLGLKGQW-------RDAALQALAAVGL---ADRANEWPAALSGGQKQRVA 143

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDV 247
Cdd:PRK11247 144 LARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 340-547 8.71e-21

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 96.73  E-value: 8.71e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRtmrRSVQMIFQDPFasldprM 419
Cdd:TIGR01193 489 ILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTLR---QFINYLPQEPY------I 559

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  420 SVGTAIMEPFIEHRLGTKQQAREKAADLLEkvglSPDMMRRFPHEF-----------SGGQRQRIAIARSLMLDPKVIVA 488
Cdd:TIGR01193 560 FSGSILENLLLGAKENVSQDEIWAACEIAE----IKDDIENMPLGYqtelseegssiSGGQKQRIALARALLTDSKVLIL 635

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341  489 DEAVSALDVSIKAQVcnlLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEIVEIG 547
Cdd:TIGR01193 636 DESTSNLDTITEKKI---VNNLLNLQDKTIIFVAHRLSVAKQ-SDKIIVLDHGKIIEQG 690
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 19-260 1.25e-20

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 91.14  E-value: 1.25e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTtsFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKS-VTSLsIMRLLDKKtsriEGKVMLGGRDLLALPEEE 97
Cdd:cd03251    1 VEFKNVT--FRYPGDGPPVLRDISLDIPAGETVALVGPSGSGKStLVNL-IPRFYDVD----SGRILIDGHDVRDYTLAS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 MRkvrgKDISMIFQEPMtslnpIFpigkqiaeALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQF-------- 169
Cdd:cd03251   74 LR----RQIGLVSQDVF-----LF--------NDTVAENIAYGRPGATREEVEEAARAANAHEFIMELPEGYdtvigerg 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 ---SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeeEGMSVLFITHDMGVVaEVSDRTIVMFRGD 246
Cdd:cd03251  137 vklSGGQRQRIAIARALLKDPPILILDEATSALDTESERLVQAALERLM--KNRTTFVIAHRLSTI-ENADRIVVLEDGK 213

                        250
                 ....*....|....
gi 549799341 247 VVETGTTDDIFHRG 260
Cdd:cd03251  214 IVERGTHEELLAQG 227
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 341-558 1.37e-20

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 90.99  E-value: 1.37e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldktTLRTMRRSVqmIFQDpfASLDPRMS 420
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQI------TEPGPDRMV--VFQN--YSLLPWLT 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  421 V--GTAIMEPFIEHRLGTKQQaREKAADLLEKVGLSPDMMRRfPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVS 498
Cdd:TIGR01184  71 VreNIALAVDRVLPDLSKSER-RAIVEEHIALVGLTEAADKR-PGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDAL 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341  499 IKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVM------YLGEIVEIG-----PRAAVFDNPQH 558
Cdd:TIGR01184 149 TRGNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLtngpaaNIGQILEVPfprprDRLEVVEDPSY 219
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 27-251 1.39e-20

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 90.73  E-value: 1.39e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  27 SFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEMRKvrgkDI 106
Cdd:cd03245    9 SFSYPNQEIPALDNVSLTIRAGEKVAIIGRVGSGKS-TLLKLLAGLYKPTS---GSVLLDGTDIRQLDPADLRR----NI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 107 SMIFQEPMtslnpIFpigkqiaeALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQF-----------SGGMRQ 175
Cdd:cd03245   81 GYVPQDVT-----LF--------YGTLRDNITLGAPLADDERILRAAELAGVTDFVNKHPNGLdlqigergrglSGGQRQ 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEgmSVLFITHDMGVVAEVsDRTIVMFRGDVVETG 251
Cdd:cd03245  148 AVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGDK--TLIIITHRPSLLDLV-DRIIVMDSGRIVADG 220
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 310-552 1.75e-20

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 95.09  E-value: 1.75e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 310 GRTPILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEV 389
Cdd:COG3845    1 MMPPALELRGITKRF-----------GGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPV 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 390 lkldktTLRT----MRRSVQMIFQDPfaSLDPRMSV------GtaiMEPFIEHRLGTKQqAREKAADLLEKVGLSPDMMR 459
Cdd:COG3845   70 ------RIRSprdaIALGIGMVHQHF--MLVPNLTVaenivlG---LEPTKGGRLDRKA-ARARIRELSERYGLDVDPDA 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 460 RfPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSAL---------DV--SIKAQVCnllldlqqnlnlAFLFISHDMAVV 528
Cdd:COG3845  138 K-VEDLSVGEQQRVEILKALYRGARILILDEPTAVLtpqeadelfEIlrRLAAEGK------------SIIFITHKLREV 204

                        250       260
                 ....*....|....*....|....
gi 549799341 529 ERVSHRVAVMYLGEIVEIGPRAAV 552
Cdd:COG3845  205 MAIADRVTVLRRGKVVGTVDTAET 228
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 344-543 1.91e-20

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 90.61  E-value: 1.91e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKttlRTMRRSVQMIFQDP--FA-SLDPRMS 420
Cdd:cd03248   33 VSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEH---KYLHSKVSLVGQEPvlFArSLQDNIA 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 421 VGTA------IMEP--------FI-EHRLGTKQQAREKAADLlekvglspdmmrrfphefSGGQRQRIAIARSLMLDPKV 485
Cdd:cd03248  110 YGLQscsfecVKEAaqkahahsFIsELASGYDTEVGEKGSQL------------------SGGQKQRVAIARALIRNPQV 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 486 IVADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEI 543
Cdd:cd03248  172 LILDEATSALDAESEQQV--QQALYDWPERRTVLVIAHRLSTVER-ADQILVLDGGRI 226
cbiO PRK13644
energy-coupling factor transporter ATPase;
38-282 1.92e-20

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 91.59  E-value: 1.92e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  38 VRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLLALPE-EEMRKVRGkdisMIFQEPMTS 116
Cdd:PRK13644  18 LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQ----KGKVLVSGIDTGDFSKlQGIRKLVG----IVFQNPETQ 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 117 LnpifpIGKQIAEALTVHQD---ISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVMIAMALASKPKLLIAD 193
Cdd:PRK13644  90 F-----VGRTVEEDLAFGPEnlcLPPIEIRKRVDRALAEIGLEKYRHR---SPKTLSGGQGQCVALAGILTMEPECLIFD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 194 EPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVaEVSDRTIVMFRGDVVETGTTDDIFhrgRHPYTRALLSAVP 273
Cdd:PRK13644 162 EVTSMLDPDSGIAVLERIKKLH-EKGKTIVYITHNLEEL-HDADRIIVMDRGKIVLEGEPENVL---SDVSLQTLGLTPP 236


                 ....*....
gi 549799341 274 KLGSMKERL 282
Cdd:PRK13644 237 SLIELAENL 245
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 20-272 3.20e-20

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 90.53  E-value: 3.20e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  20 SVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIM-RLLDKKtsriEGKVMLGGRDLLALPEEEM 98
Cdd:COG4604    3 EIKNVSKRY----GGKVVLDDVSLTIPKGGITALIGPNGAGKS-TLLSMIsRLLPPD----SGEVLVDGLDVATTPSREL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVrgkdISMIFQEPMTSLNpifpigkqiaeaLTVHQDIS-----------SSAAKAEVIRLLEKVRIPNAKNRFDDyph 167
Cdd:COG4604   74 AKR----LAILRQENHINSR------------LTVRELVAfgrfpyskgrlTAEDREIIDEAIAYLDLEDLADRYLD--- 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 168 QFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDV 247
Cdd:COG4604  135 ELSGGQRQRAFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRV 214

                        250       260
                 ....*....|....*....|....*
gi 549799341 248 VETGTTDDIFhrgrhpyTRALLSAV 272
Cdd:COG4604  215 VAQGTPEEII-------TPEVLSDI 232
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 38-282 4.13e-20

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 90.68  E-value: 4.13e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  38 VRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdKKTSrieGKVMLGGRDLlALPEEEMRKVRgKDISMIFQEPMtsl 117
Cdd:PRK13636  22 LKGININIKKGEVTAILGGNGAGKSTLFQNLNGIL-KPSS---GRILFDGKPI-DYSRKGLMKLR-ESVGMVFQDPD--- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 118 NPIFpigkqiaeALTVHQDISSSA---------AKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVMIAMALASKPK 188
Cdd:PRK13636  93 NQLF--------SASVYQDVSFGAvnlklpedeVRKRVDNALKRTGIEHLKDK---PTHCLSFGQKKRVAIAGVLVMEPK 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 189 LLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFhrGRHPYTRAL 268
Cdd:PRK13636 162 VLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF--AEKEMLRKV 239

                        250
                 ....*....|....
gi 549799341 269 LSAVPKLGSMKERL 282
Cdd:PRK13636 240 NLRLPRIGHLMEIL 253
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 35-260 5.12e-20

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 94.40  E-value: 5.12e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   35 KSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLlalPEEEMRKVRGKdISMIFQEPM 114
Cdd:TIGR00958 494 VPVLKGLTFTLHPGEVVALVGPSGSGKS----TVAALLQNLYQPTGGQVLLDGVPL---VQYDHHYLHRQ-VALVGQEPV 565

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  115 tslnpIF--PIGKQIAEALTVHQD--ISSSAAKAEVIRLLEKvrIPNAKN-RFDDYPHQFSGGMRQRVMIAMALASKPKL 189
Cdd:TIGR00958 566 -----LFsgSVRENIAYGLTDTPDeeIMAAAKAANAHDFIME--FPNGYDtEVGEKGSQLSGGQKQRIAIARALVRKPRV 638

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341  190 LIADEPTTALDVTIQgqilDLIKTLQEEEGMSVLFITHDMGVVaEVSDRTIVMFRGDVVETGTTDDIFHRG 260
Cdd:TIGR00958 639 LILDEATSALDAECE----QLLQESRSRASRTVLLIAHRLSTV-ERADQILVLKKGSVVEMGTHKQLMEDQ 704
cbiO PRK13645
energy-coupling factor transporter ATPase;
40-257 5.27e-20

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 90.84  E-value: 5.27e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  40 NMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTsrieGKVMLGGrdlLALPE-----EEMRKVRgKDISMIFQEPM 114
Cdd:PRK13645  29 NTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISET----GQTIVGD---YAIPAnlkkiKEVKRLR-KEIGLVFQFPE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 115 TSLnpiF--PIGKQIAEAlTVHQDISSSAAKAEVIRLLEKVRIPnaknrfDDY----PHQFSGGMRQRVMIAMALASKPK 188
Cdd:PRK13645 101 YQL---FqeTIEKDIAFG-PVNLGENKQEAYKKVPELLKLVQLP------EDYvkrsPFELSGGQKRRVALAGIIAMDGN 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 189 LLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIF 257
Cdd:PRK13645 171 TLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIF 239
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
33-245 7.88e-20

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 88.39  E-value: 7.88e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  33 GWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEMRKVRgKDISMIFQE 112
Cdd:PRK10908  13 GGRQALQGVTFHMRPGEMAFLTGHSGAGKS-TLLKLICGIERPSA---GKIWFSGHDITRLKNREVPFLR-RQIGMIFQD 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 113 PMTSL------NPIFPIGKQIAEALTVHQDISSSAAKaevIRLLEKvripnAKNrfddYPHQFSGGMRQRVMIAMALASK 186
Cdd:PRK10908  88 HHLLMdrtvydNVAIPLIIAGASGDDIRRRVSAALDK---VGLLDK-----AKN----FPIQLSGGEQQRVGIARAVVNK 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 187 PKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:PRK10908 156 PAVLLADEPTGNLDDALSEGILRLFEEFN-RVGVTVLMATHDIGLISRRSYRMLTLSDG 213
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 19-251 1.01e-19

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 86.98  E-value: 1.01e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLttSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALpEEEM 98
Cdd:cd03247    1 LSINNV--SFSYPEQEQQVLKNLSLELKQGEKIALLGRSGSGKS----TLLQLLTGDLKPQQGEITLDGVPVSDL-EKAL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVrgkdISMIFQEPMtslnpIFpigkqiaeALTVHQDISSsaakaevirllekvripnaknrfddyphQFSGGMRQRVM 178
Cdd:cd03247   74 SSL----ISVLNQRPY-----LF--------DTTLRNNLGR----------------------------RFSGGERQRLA 108

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTIQGQILDLIktLQEEEGMSVLFITHDMGVVAEVsDRTIVMFRGDVVETG 251
Cdd:cd03247  109 LARILLQDAPIVLLDEPTVGLDPITERQLLSLI--FEVLKDKTLIWITHHLTGIEHM-DKILFLENGKIIMQG 178
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
344-568 1.28e-19

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 90.53  E-value: 1.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldkTTLRTMRRSVQMIFQDpfASLDPRMSVGT 423
Cdd:PRK10851  21 ISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDV-----SRLHARDRKVGFVFQH--YALFRHMTVFD 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 424 AI-----MEPfiEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVS 498
Cdd:PRK10851  94 NIafgltVLP--RRERPNAAAIKAKVTQLLEMVQLA-HLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQ 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 499 IKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQHPYTKKLMSAV 568
Cdd:PRK10851 171 VRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFMGEV 240
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 338-544 1.31e-19

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 87.65  E-value: 1.31e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 338 VHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLrtmRRSVQMIFQDP---FAS 414
Cdd:cd03245   17 IPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADL---RRNIGYVPQDVtlfYGT 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 415 LDPRMSVGtaimEPFIEhrlgtkQQAREKAADLLekvGLSpDMMRRFPHEF-----------SGGQRQRIAIARSLMLDP 483
Cdd:cd03245   94 LRDNITLG----APLAD------DERILRAAELA---GVT-DFVNKHPNGLdlqigergrglSGGQRQAVALARALLNDP 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341 484 KVIVADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERVShRVAVMYLGEIV 544
Cdd:cd03245  160 PILLLDEPTSAMDMNSEERL--KERLRQLLGDKTLIIITHRPSLLDLVD-RIIVMDSGRIV 217
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 19-252 1.35e-19

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 87.47  E-value: 1.35e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFRVDggWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKktsrIEGKVMLGGRDLLALPEEEM 98
Cdd:cd03369    7 IEVENLSVRYAPD--LPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEA----EEGKIEIDGIDISTIPLEDL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RkvrgKDISMIFQEPM----TSLNPIFPIGK----QIAEALTVHQDISSsaakaevirllekvripnaknrfddyphqFS 170
Cdd:cd03369   81 R----SSLTIIPQDPTlfsgTIRSNLDPFDEysdeEIYGALRVSEGGLN-----------------------------LS 127

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 171 GGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTlqEEEGMSVLFITHDMGVVAEVsDRTIVMFRGDVVET 250
Cdd:cd03369  128 QGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTIRE--EFTNSTILTIAHRLRTIIDY-DKILVMDAGEVKEY 204


                 ..
gi 549799341 251 GT 252
Cdd:cd03369  205 DH 206
cbiO PRK13643
energy-coupling factor transporter ATPase;
337-553 1.48e-19

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 89.41  E-value: 1.48e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 337 AVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTT-LRTMRRSVQMIFQDPFASL 415
Cdd:PRK13643  18 ASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKeIKPVRKKVGVVFQFPESQL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAIMEPfieHRLG-TKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:PRK13643  98 FEETVLKDVAFGP---QNFGiPKEKAEKIAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAG 174

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 495 LDVSIKAQVCNLLLDLQQNLNLAFLfISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVF 553
Cdd:PRK13643 175 LDPKARIEMMQLFESIHQSGQTVVL-VTHLMDDVADYADYVYLLEKGHIISCGTPSDVF 232
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 16-259 1.57e-19

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 88.21  E-value: 1.57e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFRV------------------DGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMrlldkktS 77
Cdd:COG1134    2 SSMIEVENVSKSYRLyhepsrslkelllrrrrtRREEFWALKDVSFEVERGESVGIIGRNGAGKS-TLLKLI-------A 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  78 RI----EGKVmlggrdllalpeeemrKVRGKDISMIfqEPMTSLNPifpigkqiaeALTVHQDISSSAA-----KAEVIR 148
Cdd:COG1134   74 GIleptSGRV----------------EVNGRVSALL--ELGAGFHP----------ELTGRENIYLNGRllglsRKEIDE 125

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 149 LLEKVR----IpnakNRFDDYP-HQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVL 223
Cdd:COG1134  126 KFDEIVefaeL----GDFIDQPvKTYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELR-ESGRTVI 200

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 549799341 224 FITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHR 259
Cdd:COG1134  201 FVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAA 236
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 42-253 2.12e-19

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 87.22  E-value: 2.12e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   42 SFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEmrkvrgKDISMIFQEpmtslNPIF 121
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKS----TLLNLIAGFIEPASGSIKVNDQSHTGLAPYQ------RPVSMLFQE-----NNLF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  122 PigkqiaeALTVHQDISSSAAKAEVIRLLEKVRIPNAKNR--FDDY----PHQFSGGMRQRVMIAMALASKPKLLIADEP 195
Cdd:TIGR01277  83 A-------HLTVRQNIGLGLHPGLKLNAEQQEKVVDAAQQvgIADYldrlPEQLSGGQRQRVALARCLVRPNPILLLDEP 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341  196 TTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTT 253
Cdd:TIGR01277 156 FSALDPLLREEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVSDC 213
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 345-556 2.35e-19

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 92.48  E-value: 2.35e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  345 SFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSVQmifQDPfasldprMSVGTA 424
Cdd:TIGR00958 501 TFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLHRQVALVG---QEP-------VLFSGS 570

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  425 IMEPfIEHRLGTKQQAREKAAdllEKVGLSPDMMRRFPHEF-----------SGGQRQRIAIARSLMLDPKVIVADEAVS 493
Cdd:TIGR00958 571 VREN-IAYGLTDTPDEEIMAA---AKAANAHDFIMEFPNGYdtevgekgsqlSGGQKQRIAIARALVRKPRVLILDEATS 646

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341  494 ALDVSIKAQVcnllLDLQQNLNLAFLFISHDMAVVERvSHRVAVMYLGEIVEIGPRAAVFDNP 556
Cdd:TIGR00958 647 ALDAECEQLL----QESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDQ 704
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 335-556 2.65e-19

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 88.32  E-value: 2.65e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 335 SGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlklDKTTLRTMRRSVQMIFQDPfas 414
Cdd:PRK13652  14 SGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPI---TKENIREVRKFVGLVFQNP--- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 415 ldprmsvGTAIMEPFIEH-------RLGTKQQARE-KAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVI 486
Cdd:PRK13652  88 -------DDQIFSPTVEQdiafgpiNLGLDEETVAhRVSSALHMLGLE-ELRDRVPHHLSGGEKKRVAIAGVIAMEPQVL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 487 VADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNP 556
Cdd:PRK13652 160 VLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 19-252 3.03e-19

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 87.43  E-value: 3.03e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTtsFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRllDKKTSRIEGKVMLGGRDLLALPEEEm 98
Cdd:COG0396    1 LEIKNLH--VSVEG--KEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMG--HPKYEVTSGSILLDGEDILELSPDE- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGkdISMIFQEPM------------TSLNpifpigkQIAEaltvhQDISSSAAKAEVIRLLEKVRIPnaknrfDDYP 166
Cdd:COG0396   74 RARAG--IFLAFQYPVeipgvsvsnflrTALN-------ARRG-----EELSAREFLKLLKEKMKELGLD------EDFL 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 167 HQ-----FSGGMRQRVMIAMALASKPKLLIADEPTTALDVtiqgqilDLIKTLQE------EEGMSVLFITHDMGVVAEV 235
Cdd:COG0396  134 DRyvnegFSGGEKKRNEILQMLLLEPKLAILDETDSGLDI-------DALRIVAEgvnklrSPDRGILIITHYQRILDYI 206

                        250
                 ....*....|....*...
gi 549799341 236 S-DRTIVMFRGDVVETGT 252
Cdd:COG0396  207 KpDFVHVLVDGRIVKSGG 224
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
170-402 3.99e-19

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 91.72  E-value: 3.99e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEE-EGMSVLFITHDMGVvAEVSDRTIVMFRGDVV 248
Cdd:NF033858 138 SGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAErPGMSVLVATAYMEE-AERFDWLVAMDAGRVL 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 249 ETGTTDDIFHRgrhpyTRAllsavPKLGSMKERLLPARfpiidiKTGESQPVADVKDTVSGGRTPILSVKDLTTRFdirs 328
Cdd:NF033858 217 ATGTPAELLAR-----TGA-----DTLEAAFIALLPEE------KRRGHQPVVIPPRPADDDDEPAIEARGLTMRF---- 276

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 329 glfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlklDKTTLRTMRR 402
Cdd:NF033858 277 -------GDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPV---DAGDIATRRR 340
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 328-543 4.48e-19

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 84.96  E-value: 4.48e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 328 SGLFGRKSGAVHAV-EKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRtmrRSVQM 406
Cdd:cd03246    4 ENVSFRYPGAEPPVlRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELG---DHVGY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 407 IFQDpfasldprmsvgtaimepfIEHRLGTkqqarekaadLLEKVglspdmmrrfpheFSGGQRQRIAIARSLMLDPKVI 486
Cdd:cd03246   81 LPQD-------------------DELFSGS----------IAENI-------------LSGGQRQRLGLARALYGNPRIL 118

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 487 VADEAVSALDVSIKAQVCNLLLDLQQNLNLAfLFISHDMAVVERVShRVAVMYLGEI 543
Cdd:cd03246  119 VLDEPNSHLDVEGERALNQAIAALKAAGATR-IVIAHRPETLASAD-RILVLEDGRV 173
NHLM_micro_ABC2 TIGR03797
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ...
 296-548 5.46e-19

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274789 [Multi-domain]  Cd Length: 686  Bit Score: 91.17  E-value: 5.46e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  296 ESQPVADVKDTVSGGRTPilsVKDLTTRFDIRSGLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLI 375
Cdd:TIGR03797 427 RAKPILEALPEVDEAKTD---PGKLSGAIEVDRVTFRYRPDGPLILDDVSLQIEPGEFVAIVGPSGSGKSTLLRLLLGFE 503

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  376 EPTSGDVMLDGYEVLKLDKttlRTMRRSVQMIFQDPfasldpRMSVGTaIMEPFIEHRLGTKQQAREKAadllEKVGLSP 455
Cdd:TIGR03797 504 TPESGSVFYDGQDLAGLDV---QAVRRQLGVVLQNG------RLMSGS-IFENIAGGAPLTLDEAWEAA----RMAGLAE 569

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  456 DMmRRFP---H--------EFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLnlafLFISHD 524
Cdd:TIGR03797 570 DI-RAMPmgmHtvisegggTLSGGQRQRLLIARALVRKPRILLFDEATSALDNRTQAIVSESLERLKVTR----IVIAHR 644

                         250       260
                  ....*....|....*....|....
gi 549799341  525 MAVVeRVSHRVAVMYLGEIVEIGP 548
Cdd:TIGR03797 645 LSTI-RNADRIYVLDAGRVVQQGT 667
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 310-557 5.54e-19

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 87.11  E-value: 5.54e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 310 GRTPILSVKDLTtrfdirsglFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMldgYEV 389
Cdd:PRK13648   3 DKNSIIVFKNVS---------FQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIF---YNN 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 390 LKLDKTTLRTMRRSVQMIFQDPfasldPRMSVGTAIMEPF---IEHRLGTKQQAREKAADLLEKVglspDMMRRF---PH 463
Cdd:PRK13648  71 QAITDDNFEKLRKHIGIVFQNP-----DNQFVGSIVKYDVafgLENHAVPYDEMHRRVSEALKQV----DMLERAdyePN 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 464 EFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHrVAVMYLGEI 543
Cdd:PRK13648 142 ALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADH-VIVMNKGTV 220

                        250
                 ....*....|....
gi 549799341 544 VEIGPRAAVFDNPQ 557
Cdd:PRK13648 221 YKEGTPTEIFDHAE 234
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
340-496 6.05e-19

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 90.46  E-value: 6.05e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEvlkLDKTTLRTMRRSVQMI------FQDPFA 413
Cdd:PRK11176 358 ALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHD---LRDYTLASLRNQVALVsqnvhlFNDTIA 434

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 414 SldprmSVGTAIMEPFiehrlgTKQQArEKAAdlleKVGLSPDMMRRFPHEF-----------SGGQRQRIAIARSLMLD 482
Cdd:PRK11176 435 N-----NIAYARTEQY------SREQI-EEAA----RMAYAMDFINKMDNGLdtvigengvllSGGQRQRIAIARALLRD 498

                        170
                 ....*....|....
gi 549799341 483 PKVIVADEAVSALD 496
Cdd:PRK11176 499 SPILILDEATSALD 512
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 16-543 9.42e-19

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 89.68  E-value: 9.42e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFRvdgGWKSVvRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDL-LALP 94
Cdd:PRK10762   2 QALLQLKGIDKAFP---GVKAL-SGAALNVYPGRVMALVGENGAGKS----TMMKVLTGIYTRDAGSILYLGKEVtFNGP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 eeemRKVRGKDISMIFQEpmtsLNPIFPIgkQIAEALTVHQDISSSAAK-------AEVIRLLEKVRIPNAknrfddyPH 167
Cdd:PRK10762  74 ----KSSQEAGIGIIHQE----LNLIPQL--TIAENIFLGREFVNRFGRidwkkmyAEADKLLARLNLRFS-------SD 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 168 QFSG----GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEeGMSVLFITHDMGVVAEVSDRTIVM- 242
Cdd:PRK10762 137 KLVGelsiGEQQMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRLKEIFEICDDVTVFr 215

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 243 ---FRGD-VVETGTTDDIFHRgrhpytrallsavpklgsMKERLLPARFPIIDIKTGESQpvadvkdtvsggrtpiLSVK 318
Cdd:PRK10762 216 dgqFIAErEVADLTEDSLIEM------------------MVGRKLEDQYPRLDKAPGEVR----------------LKVD 261

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 319 DLttrfdirsglfgrkSGAvhAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLklDKTTLR 398
Cdd:PRK10762 262 NL--------------SGP--GVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVV--TRSPQD 323

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 399 TMRRSVQMIFQDPFA-------SLDPRMSVgTAImePFIEHRLGTKQQAREKAA--DLLEKVGLSPDMMRRFPHEFSGGQ 469
Cdd:PRK10762 324 GLANGIVYISEDRKRdglvlgmSVKENMSL-TAL--RYFSRAGGSLKHADEQQAvsDFIRLFNIKTPSMEQAIGLLSGGN 400

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 470 RQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLfISHDMAVVERVSHRVAVMYLGEI 543
Cdd:PRK10762 401 QQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAEGLSIIL-VSSEMPEVLGMSDRILVMHEGRI 473
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 317-496 9.60e-19

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 87.45  E-value: 9.60e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 317 VKDLTTRFDIRSGLfgrksgAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDV-----------MLD 385
Cdd:PRK13651   5 VKNIVKIFNKKLPT------ELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewifkdeknkkKTK 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 386 GYEVLKLD----KTTLRT------MRRSVQMIFQdpFASLDprmsvgtaIMEPFIEH-------RLGT-KQQAREKAADL 447
Cdd:PRK13651  79 EKEKVLEKlviqKTRFKKikkikeIRRRVGVVFQ--FAEYQ--------LFEQTIEKdiifgpvSMGVsKEEAKKRAAKY 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 549799341 448 LEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:PRK13651 149 IELVGLDESYLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLD 197
cbiO PRK13640
energy-coupling factor transporter ATPase;
314-557 1.01e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 86.78  E-value: 1.01e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTtrfdirsglFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGD---VMLDGyevL 390
Cdd:PRK13640   5 IVEFKHVS---------FTYPDSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPnskITVDG---I 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 391 KLDKTTLRTMRRSVQMIFQDPfaslDPRMsVGTAIMEPF---IEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSG 467
Cdd:PRK13640  73 TLTAKTVWDIREKVGIVFQNP----DNQF-VGATVGDDVafgLENRAVPRPEMIKIVRDVLADVGML-DYIDSEPANLSG 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 468 GQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVErVSHRVAVMYLGEIVEIG 547
Cdd:PRK13640 147 GQKQRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEAN-MADQVLVLDDGKLLAQG 225

                        250
                 ....*....|
gi 549799341 548 PRAAVFDNPQ 557
Cdd:PRK13640 226 SPVEIFSKVE 235
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 296-537 1.04e-18

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 89.65  E-value: 1.04e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  296 ESQPVADVKDTVSGGRTPILSVKDLTTRFdirSGLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLI 375
Cdd:TIGR02857 296 ALFAVLDAAPRPLAGKAPVTAAPASSLEF---SGVSVAYPGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFV 372

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  376 EPTSGDVMLDGYEVLKLDKTTLRtmrRSVQMIFQDPFasldprMSVGTaIMEpfiEHRLGTKQQAREKAADLLEKVGLS- 454
Cdd:TIGR02857 373 DPTEGSIAVNGVPLADADADSWR---DQIAWVPQHPF------LFAGT-IAE---NIRLARPDASDAEIREALERAGLDe 439

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  455 -----PDMMRRF----PHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDM 525
Cdd:TIGR02857 440 fvaalPQGLDTPigegGAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEV--LEALRALAQGRTVLLVTHRL 517

                         250
                  ....*....|..
gi 549799341  526 AVVERVSHRVAV 537
Cdd:TIGR02857 518 ALAALADRIVVL 529
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 19-257 1.13e-18

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 85.29  E-value: 1.13e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPeeeM 98
Cdd:cd03218    1 LRAENLSKRY----GKRKVVNGVSLSVKQGEIVGLLGPNGAGKT-TTFYMIVGLVKPDS---GKILLDGQDITKLP---M 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGKDISMIFQEPmtslnPIFpigkqiaEALTVHQDISssaAKAEVIRLLEKVRIPNAKNRFDDYP-----HQF---- 169
Cdd:cd03218   70 HKRARLGIGYLPQEA-----SIF-------RKLTVEENIL---AVLEIRGLSKKEREEKLEELLEEFHithlrKSKassl 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVE 249
Cdd:cd03218  135 SGGERRRVEIARALATNPKFLLLDEPFAGVDPIAVQDIQKIIKILK-DRGIGVLITDHNVRETLSITDRAYIIYEGKVLA 213


                 ....*...
gi 549799341 250 TGTTDDIF 257
Cdd:cd03218  214 EGTPEEIA 221
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 13-247 1.19e-18

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 85.22  E-value: 1.19e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  13 GSVSP-----VLSVQNLTTSFRVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGG 87
Cdd:cd03248    1 GSLAPdhlkgIVKFQNVTFAYPTRPD-TLVLQDVSFTLHPGEVTALVGPSGSGKS----TVVALLENFYQPQGGQVLLDG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  88 RDLLALPEEEMRKVrgkdISMIFQEPMTSlnpifpigkqiaeALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPH 167
Cdd:cd03248   76 KPISQYEHKYLHSK----VSLVGQEPVLF-------------ARSLQDNIAYGLQSCSFECVKEAAQKAHAHSFISELAS 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 168 -----------QFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKtlQEEEGMSVLFITHDMGVVaEVS 236
Cdd:cd03248  139 gydtevgekgsQLSGGQKQRVAIARALIRNPQVLILDEATSALDAESEQQVQQALY--DWPERRTVLVIAHRLSTV-ERA 215

                        250
                 ....*....|.
gi 549799341 237 DRTIVMFRGDV 247
Cdd:cd03248  216 DQILVLDGGRI 226
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 314-553 1.41e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 86.44  E-value: 1.41e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFdirsglfgrkSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyEVLKLD 393
Cdd:PRK13636   5 ILKVEELNYNY----------SDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDG-KPIDYS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 KTTLRTMRRSVQMIFQDP-----FASLDPRMSVGTAIMEPfiehrlgTKQQAREKAADLLEKVGLSPdmMRRFP-HEFSG 467
Cdd:PRK13636  74 RKGLMKLRESVGMVFQDPdnqlfSASVYQDVSFGAVNLKL-------PEDEVRKRVDNALKRTGIEH--LKDKPtHCLSF 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 468 GQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:PRK13636 145 GQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQG 224


                 ....*.
gi 549799341 548 PRAAVF 553
Cdd:PRK13636 225 NPKEVF 230
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 21-251 1.50e-18

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 85.08  E-value: 1.50e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  21 VQNLTTSFRV---DGGWKS--------------VVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKV 83
Cdd:cd03267    3 VSNLSKSYRVyskEPGLIGslkslfkrkyreveALKGISFTIEKGEIVGFIGPNGAGKT-TTLKILSGLLQPTS---GEV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  84 MLGGRdllaLPEEEMRKVRgKDISMIFQEpMTSLNPIFPIgkqiAEALTVHQDI---SSSAAKAEVIRLLEKVRIpnakN 160
Cdd:cd03267   79 RVAGL----VPWKRRKKFL-RRIGVVFGQ-KTQLWWDLPV----IDSFYLLAAIydlPPARFKKRLDELSELLDL----E 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 161 RFDDYP-HQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRT 239
Cdd:cd03267  145 ELLDTPvRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRV 224

                        250
                 ....*....|..
gi 549799341 240 IVMFRGDVVETG 251
Cdd:cd03267  225 LVIDKGRLLYDG 236
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 14-256 2.29e-18

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 85.04  E-value: 2.29e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  14 SVSPVLSVQNLTTSFrvdGGWKSVvRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLAL 93
Cdd:PRK11300   1 MSQPLLSVSGLMMRF---GGLLAV-NNVNLEVREQEIVSLIGPNGAGKT-TVFNCLTGFYKPTG---GTILLRGQHIEGL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  94 PEEEM-RK--VRGKDISMIFQEpMTSLnpifpigkqiaEALTV--HQDISSS------------AAKAEVIRL----LEK 152
Cdd:PRK11300  73 PGHQIaRMgvVRTFQHVRLFRE-MTVI-----------ENLLVaqHQQLKTGlfsgllktpafrRAESEALDRaatwLER 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 153 VRIPNAKNRFDD---YPHQfsggmrQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDM 229
Cdd:PRK11300 141 VGLLEHANRQAGnlaYGQQ------RRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDM 214

                        250       260
                 ....*....|....*....|....*..
gi 549799341 230 GVVAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:PRK11300 215 KLVMGISDRIYVVNQGTPLANGTPEEI 241
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
37-260 2.90e-18

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 85.06  E-value: 2.90e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  37 VVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRI--EGKVM-LGGRDLLALPEEemrkvrgkdISMIFQEP 113
Cdd:PRK13638  16 VLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVlwQGKPLdYSKRGLLALRQQ---------VATVFQDP 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 114 MTSlnpIF--PIGKQIAEALTvhqdiSSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQ-FSGGMRQRVMIAMALASKPKLL 190
Cdd:PRK13638  87 EQQ---IFytDIDSDIAFSLR-----NLGVPEAEITRRVDEALTLVDAQHFRHQPIQcLSHGQKKRVAIAGALVLQARYL 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 191 IADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRG 260
Cdd:PRK13638 159 LLDEPTAGLDPAGRTQMIAIIRRIV-AQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFACT 227
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 19-268 3.03e-18

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 88.23  E-value: 3.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   19 LSVQNLTTSFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEM 98
Cdd:TIGR02203 331 VEFRNVTFRYPGRD--RPALDSISLVIEPGETVALVGRSGSGKS----TLVNLIPRFYEPDSGQILLDGHDLADYTLASL 404

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   99 RKvrgkDISMIFQEPMTSLNPIFpigKQIAEALTvhqdisSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQ--------FS 170
Cdd:TIGR02203 405 RR----QVALVSQDVVLFNDTIA---NNIAYGRT------EQADRAEIERALAAAYAQDFVDKLPLGLDTpigengvlLS 471

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  171 GGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeeEGMSVLFITHDMGVVaEVSDRTIVMFRGDVVET 250
Cdd:TIGR02203 472 GGQRQRLAIARALLKDAPILILDEATSALDNESERLVQAALERLM--QGRTTLVIAHRLSTI-EKADRIVVMDDGRIVER 548

                         250
                  ....*....|....*....
gi 549799341  251 GTTDDIF-HRGRHPYTRAL 268
Cdd:TIGR02203 549 GTHNELLaRNGLYAQLHNM 567
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 315-547 4.01e-18

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 82.36  E-value: 4.01e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTtrfdirsglFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDK 394
Cdd:cd03247    1 LSINNVS---------FSYPEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEK 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 ttlrTMRRSVQMIFQDPFAsldprmsvgtaimepFiehrlgtkqqarekAADLLEKVGlspdmmRRfpheFSGGQRQRIA 474
Cdd:cd03247   72 ----ALSSLISVLNQRPYL---------------F--------------DTTLRNNLG------RR----FSGGERQRLA 108

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 475 IARSLMLDPKVIVADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERVShRVAVMYLGEIVEIG 547
Cdd:cd03247  109 LARILLQDAPIVLLDEPTVGLDPITERQL--LSLIFEVLKDKTLIWITHHLTGIEHMD-KILFLENGKIIMQG 178
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 18-248 5.89e-18

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 82.21  E-value: 5.89e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVD--GGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSR--IEGKVMLGGRDLlal 93
Cdd:cd03213    3 TLSFRNLTVTVKSSpsKSGKQLLKNVSGKAKPGELTAIMGPSGAGKS----TLLNALAGRRTGlgVSGEVLINGRPL--- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  94 PEEEMRKVrgkdISMIFQEPMTSLNpifpigkqiaeaLTVHQDISSSAAkaevIRLLekvripnaknrfddyphqfSGGM 173
Cdd:cd03213   76 DKRSFRKI----IGYVPQDDILHPT------------LTVRETLMFAAK----LRGL-------------------SGGE 116

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 174 RQRVMIAMALASKPKLLIADEPTTALDvtiQGQILDLIKTLQE--EEGMSVLFITHD-MGVVAEVSDRTIVMFRGDVV 248
Cdd:cd03213  117 RKRVSIALELVSNPSLLFLDEPTSGLD---SSSALQVMSLLRRlaDTGRTIICSIHQpSSEIFELFDKLLLLSQGRVI 191
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 312-554 6.87e-18

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 83.59  E-value: 6.87e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFDIRSGLFGR-----------KSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSG 380
Cdd:COG1134    2 SSMIEVENVSKSYRLYHEPSRSlkelllrrrrtRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 381 DVMLDGyevlkldkttlrtmrRSVQMIfqDPFASLDPRMS-------VGTAimepfiehrLG-TKQQAREKAADLLEKVG 452
Cdd:COG1134   82 RVEVNG---------------RVSALL--ELGAGFHPELTgreniylNGRL---------LGlSRKEIDEKFDEIVEFAE 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 453 LSP--DM-MRRfpheFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQvCNLLLDLQQNLNLAFLFISHDMAVVE 529
Cdd:COG1134  136 LGDfiDQpVKT----YSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKK-CLARIRELRESGRTVIFVSHSMGAVR 210

                        250       260
                 ....*....|....*....|....*
gi 549799341 530 RVSHRVAVMYLGEIVEIGPRAAVFD 554
Cdd:COG1134  211 RLCDRAIWLEKGRLVMDGDPEEVIA 235
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 315-547 1.13e-17

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 81.86  E-value: 1.13e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfGRKsgavHAVEKVSFDLAEGeTLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKldk 394
Cdd:cd03264    1 LQLENLTKRY-------GKK----RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLK--- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 tTLRTMRRSVQMIFQDPfaSLDPRMSVgtaimEPFIEH--RLG--TKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQR 470
Cdd:cd03264   66 -QPQKLRRRIGYLPQEF--GVYPNFTV-----REFLDYiaWLKgiPSKEVKARVDEVLELVNLG-DRAKKKIGSLSGGMR 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 471 QRIAIARSLMLDPKVIVADEAVSALD-----------VSIKAQVCnllldlqqnlnlaFLFISHDMAVVERVSHRVAVMY 539
Cdd:cd03264  137 RRVGIAQALVGDPSILIVDEPTAGLDpeerirfrnllSELGEDRI-------------VILSTHIVEDVESLCNQVAVLN 203


                 ....*...
gi 549799341 540 LGEIVEIG 547
Cdd:cd03264  204 KGKLVFEG 211
cbiO PRK13643
energy-coupling factor transporter ATPase;
40-282 1.31e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 83.63  E-value: 1.31e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  40 NMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGgrDLLALP---EEEMRKVRgKDISMIFQEPMTS 116
Cdd:PRK13643  24 DIDLEVKKGSYTALIGHTGSGKS----TLLQHLNGLLQPTEGKVTVG--DIVVSStskQKEIKPVR-KKVGVVFQFPESQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 117 LNPIfPIGKQIAEAltvHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPT 196
Cdd:PRK13643  97 LFEE-TVLKDVAFG---PQNFGIPKEKAEKIAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPT 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 197 TALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHrgRHPYTRALLSAVPKLG 276
Cdd:PRK13643 173 AGLDPKARIEMMQLFESIH-QSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQ--EVDFLKAHELGVPKAT 249


                 ....*.
gi 549799341 277 SMKERL 282
Cdd:PRK13643 250 HFADQL 255
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 19-227 1.34e-17

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 86.40  E-value: 1.34e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFRvDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLdkktSRI----EGKVML-GGRDLLAL 93
Cdd:COG4178  363 LALEDLTLRTP-DG--RPLLEDLSLSLKPGERLLITGPSGSGKS----TLLRAI----AGLwpygSGRIARpAGARVLFL 431

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  94 PeeemrkvrgkdismifQEPMtslnpiFPIGKqIAEALT---VHQDISSsaakAEVIRLLEKVRIPNAKNRFD---DYPH 167
Cdd:COG4178  432 P----------------QRPY------LPLGT-LREALLypaTAEAFSD----AELREALEAVGLGHLAERLDeeaDWDQ 484

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 168 QFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKtlQEEEGMSVLFITH 227
Cdd:COG4178  485 VLSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLLR--EELPGTTVISVGH 542
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 17-256 1.36e-17

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 85.28  E-value: 1.36e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEE 96
Cdd:PRK09536   2 PMIDVSDLSVEF----GDTTVLDGVDLSVREGSLVGLVGPNGAGKT----TLLRAINGTLTPTAGTVLVAGDDVEALSAR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  97 EMrkvrGKDISMIFQEpmTSLNPIFPIGKQIAEALTVHQ---DISSSAAKAEVIRLLEKVRIpnakNRFDDYP-HQFSGG 172
Cdd:PRK09536  74 AA----SRRVASVPQD--TSLSFEFDVRQVVEMGRTPHRsrfDTWTETDRAAVERAMERTGV----AQFADRPvTSLSGG 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 173 MRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGT 252
Cdd:PRK09536 144 ERQRVLLARALAQATPVLLLDEPTASLDINHQVRTLELVRRLV-DDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGP 222


                 ....
gi 549799341 253 TDDI 256
Cdd:PRK09536 223 PADV 226
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 11-228 1.46e-17

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 85.88  E-value: 1.46e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   11 TGGSVSPVLSVQNLttSFRVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDL 90
Cdd:TIGR02868 327 AVGLGKPTLELRDL--SAGYPGA-PPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPL----QGEVTLDGVPV 399

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   91 LALPEEEMRKVrgkdISMIFQEPMtslnpIFpigkqiaeALTVHQDI---SSSAAKAEVIRLLEKVRIPNAKNRFDDYPH 167
Cdd:TIGR02868 400 SSLDQDEVRRR----VSVCAQDAH-----LF--------DTTVRENLrlaRPDATDEELWAALERVGLADWLRALPDGLD 462

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341  168 --------QFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIktLQEEEGMSVLFITHD 228
Cdd:TIGR02868 463 tvlgeggaRLSGGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDL--LAALSGRTVVLITHH 529
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 19-259 1.52e-17

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 85.96  E-value: 1.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTtsFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLD---KKTSrieGKVMLGGRDLLALPE 95
Cdd:COG4618  331 LSVENLT--VVPPGSKRPILRGVSFSLEPGEVLGVIGPSGSGKS----TLARLLVgvwPPTA---GSVRLDGADLSQWDR 401

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEmrkvRGKDISMIFQEPmtSLnpiFPIgkqiaealTVHQDIS----------SSAAKA----EVIrllekVRIPNAKN- 160
Cdd:COG4618  402 EE----LGRHIGYLPQDV--EL---FDG--------TIAENIArfgdadpekvVAAAKLagvhEMI-----LRLPDGYDt 459

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 161 RFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVtiQGQiLDLIKTLQE--EEGMSVLFITHDMGVVAEVsDR 238
Cdd:COG4618  460 RIGEGGARLSGGQRQRIGLARALYGDPRLVVLDEPNSNLDD--EGE-AALAAAIRAlkARGATVVVITHRPSLLAAV-DK 535

                        250       260
                 ....*....|....*....|.
gi 549799341 239 TIVMFRGDVVETGTTDDIFHR 259
Cdd:COG4618  536 LLVLRDGRVQAFGPRDEVLAR 556
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
33-256 2.15e-17

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 82.34  E-value: 2.15e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  33 GWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEMrkvrGKDISMIFQE 112
Cdd:PRK10253  18 GKYTVAENLTVEIPDGHFTAIIGPNGCGKS----TLLRTLSRLMTPAHGHVWLDGEHIQHYASKEV----ARRIGLLAQN 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 113 PMTSLNpiFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIA 192
Cdd:PRK10253  90 ATTPGD--ITVQELVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLL 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 193 DEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:PRK10253 168 DEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEI 231
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 336-552 2.90e-17

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 81.42  E-value: 2.90e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLdKTTLRTmRRSV------QMIFq 409
Cdd:TIGR03410  11 GQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKL-PPHERA-RAGIayvpqgREIF- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  410 dpfasldPRMSVGTAIMepfiehrLGTKQQAREKAADLLEKVGLSP---DMMRRFPHEFSGGQRQRIAIARSLMLDPKVI 486
Cdd:TIGR03410  88 -------PRLTVEENLL-------TGLAALPRRSRKIPDEIYELFPvlkEMLGRRGGDLSGGQQQQLAIARALVTRPKLL 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341  487 VADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAV 552
Cdd:TIGR03410 154 LLDEPTEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL 219
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 17-256 3.22e-17

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 81.23  E-value: 3.22e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLL--DkktsriEGKVMLGGRDLLALP 94
Cdd:COG1137    2 MTLEAENLVKSY----GKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVkpD------SGRIFLDGEDITHLP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 eeeM--RKVRGkdISMIFQEPmtSlnpIFpigkqiaEALTVHQDI---------SSSAAKAEVIRLLEKVRIPNAKNRfd 163
Cdd:COG1137   72 ---MhkRARLG--IGYLPQEA--S---IF-------RKLTVEDNIlavlelrklSKKEREERLEELLEEFGITHLRKS-- 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 164 dYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALD-VTIqGQILDLIKTLQeEEGMSVLfIT-HDmgvVAE---VSDR 238
Cdd:COG1137  133 -KAYSLSGGERRRVEIARALATNPKFILLDEPFAGVDpIAV-ADIQKIIRHLK-ERGIGVL-ITdHN---VREtlgICDR 205

                        250
                 ....*....|....*...
gi 549799341 239 TIVMFRGDVVETGTTDDI 256
Cdd:COG1137  206 AYIISEGKVLAEGTPEEI 223
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 351-496 3.80e-17

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 81.65  E-value: 3.80e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 351 GETLSLVGESGCGKSTTGRSITRLIEPTSGDvMLDGyevlkldKTTLRTMRRSVQMIFQDpfASLDPRMSVgtaimepfI 430
Cdd:PRK11247  38 GQFVAVVGRSGCGKSTLLRLLAGLETPSAGE-LLAG-------TAPLAEAREDTRLMFQD--ARLLPWKKV--------I 99

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 431 EH-RLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:PRK11247 100 DNvGLGLKGQWRDAALQALAAVGLA-DRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALD 165
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 315-547 3.87e-17

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 80.65  E-value: 3.87e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFDIRSGLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVmldgyevlkldk 394
Cdd:cd03220   12 TYKGGSSSLKKLGILGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTV------------ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 ttlrTMRRSVQMIFqDPFASLDPRMSVGTAIMepFIEHRLG-TKQQAREKAADLLEKVGLSPDMMRRFPHeFSGGQRQRI 473
Cdd:cd03220   80 ----TVRGRVSSLL-GLGGGFNPELTGRENIY--LNGRLLGlSRKEIDEKIDEIIEFSELGDFIDLPVKT-YSSGMKARL 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 474 AIARSLMLDPKVIVADEAVSALDVSIKAQvCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:cd03220  152 AFAIATALEPDILLIDEVLAVGDAAFQEK-CQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
340-525 3.90e-17

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 81.67  E-value: 3.90e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldktTLRTMRRSVqmIFQD----PFASL 415
Cdd:PRK11248  16 ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPV------EGPGAERGV--VFQNegllPWRNV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGtaimepfIEHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSAL 495
Cdd:PRK11248  88 QDNVAFG-------LQLAGVEKMQRLEIAHQMLKKVGLE-GAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGAL 159

                        170       180       190
                 ....*....|....*....|....*....|
gi 549799341 496 DVSIKAQVCNLLLDLQQNLNLAFLFISHDM 525
Cdd:PRK11248 160 DAFTREQMQTLLLKLWQETGKQVLLITHDI 189
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 18-257 4.22e-17

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 81.09  E-value: 4.22e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRvdggWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLdkktSRIEGKVMLGGRDLLALPEEE 97
Cdd:PRK10895   3 TLTAKNLAKAYK----GRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIV----PRDAGNIIIDDEDISLLPLHA 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 mRKVRGkdISMIFQEPmtSLNPIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKnrfDDYPHQFSGGMRQRV 177
Cdd:PRK10895  75 -RARRG--IGYLPQEA--SIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLR---DSMGQSLSGGERRRV 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 178 MIAMALASKPKLLIADEPTTALDVTiqgQILDLIKTLQ--EEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDD 255
Cdd:PRK10895 147 EIARALAANPKFILLDEPFAGVDPI---SVIDIKRIIEhlRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTE 223


                 ..
gi 549799341 256 IF 257
Cdd:PRK10895 224 IL 225
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 315-547 4.47e-17

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 80.15  E-value: 4.47e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDk 394
Cdd:cd03369    7 IEVENLSVRY---------APDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIP- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 ttLRTMRRSVQMIFQDPFasldprMSVGT--AIMEPFIEHrlgTKQQAREkaADLLEKVGLSpdmmrrfpheFSGGQRQR 472
Cdd:cd03369   77 --LEDLRSSLTIIPQDPT------LFSGTirSNLDPFDEY---SDEEIYG--ALRVSEGGLN----------LSQGQRQL 133

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 473 IAIARSLMLDPKVIVADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERVShRVAVMYLGEIVEIG 547
Cdd:cd03369  134 LCLARALLKRPRVLVLDEATASIDYATDALI--QKTIREEFTNSTILTIAHRLRTIIDYD-KILVMDAGEVKEYD 205
anch_rpt_ABC TIGR03771
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...
 43-256 5.45e-17

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 163483 [Multi-domain]  Cd Length: 223  Bit Score: 80.28  E-value: 5.45e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   43 FEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEemrkvrgkdISMIFQEPMTSLNpiFP 122
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKT----TLLRAILGLIPPAKGTVKVAGASPGKGWRH---------IGYVPQRHEFAWD--FP 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  123 IgkqiaealTVHQDISSSAAK-------------AEVIRLLEKVRIPNAKNRfddyP-HQFSGGMRQRVMIAMALASKPK 188
Cdd:TIGR03771  66 I--------SVAHTVMSGRTGhigwlrrpcvadfAAVRDALRRVGLTELADR----PvGELSGGQRQRVLVARALATRPS 133

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341  189 LLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRtIVMFRGDVVETGTTDDI 256
Cdd:TIGR03771 134 VLLLDEPFTGLDMPTQELLTELFIELA-GAGTAILMTTHDLAQAMATCDR-VVLLNGRVIADGTPQQL 199
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 340-566 5.53e-17

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 81.37  E-value: 5.53e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITR---LIEP--TSGDVMLDGYEVLKLDKTTLRtMRRSVQMIFQ--DPF 412
Cdd:PRK14243  25 AVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRlndLIPGfrVEGKVTFHGKNLYAPDVDPVE-VRRRIGMVFQkpNPF 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 413 A-SLDPRMSVGTAI------MEPFIEHRLgtKQQAR-EKAADLLEKVGLSpdmmrrfpheFSGGQRQRIAIARSLMLDPK 484
Cdd:PRK14243 104 PkSIYDNIAYGARIngykgdMDELVERSL--RQAALwDEVKDKLKQSGLS----------LSGGQQQRLCIARAIAVQPE 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 485 VIVADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVM---------YLGEIVEIGPRAAVFDN 555
Cdd:PRK14243 172 VILMDEPCSALDPISTLRI--EELMHELKEQYTIIIVTHNMQQAARVSDMTAFFnveltegggRYGYLVEFDRTEKIFNS 249

                        250
                 ....*....|.
gi 549799341 556 PQHPYTKKLMS 566
Cdd:PRK14243 250 PQQQATRDYVS 260
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
26-256 5.87e-17

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 81.37  E-value: 5.87e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  26 TSFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPeeemrkvrgkd 105
Cdd:PRK10575  17 VSFRVPG--RTLLHPLSLTFPAGKVTGLIGHNGSGKS----TLLKMLGRHQPPSEGEILLDAQPLESWS----------- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 106 iSMIFQEPMTSLNPIFPIgkqiAEALTVHQDIS-------------SSAAKAEVIRLLEKVRIPNAKNRFDDyphQFSGG 172
Cdd:PRK10575  80 -SKAFARKVAYLPQQLPA----AEGMTVRELVAigrypwhgalgrfGAADREKVEEAISLVGLKPLAHRLVD---SLSGG 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 173 MRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGT 252
Cdd:PRK10575 152 ERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGT 231


                 ....
gi 549799341 253 TDDI 256
Cdd:PRK10575 232 PAEL 235
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 37-256 7.25e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 81.67  E-value: 7.25e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  37 VVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLL-----------------DKKTSRIEGKVmlggrDLLALPEEEMR 99
Cdd:PRK13651  22 ALDNVSVEINQGEFIAIIGQTGSGKT-TFIEHLNALllpdtgtiewifkdeknKKKTKEKEKVL-----EKLVIQKTRFK 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 100 KVRG-----KDISMIFQepmtslnpiFPiGKQIAEAlTVHQDI---------SSSAAKAEVIRLLEKVRIPnaKNRFDDY 165
Cdd:PRK13651  96 KIKKikeirRRVGVVFQ---------FA-EYQLFEQ-TIEKDIifgpvsmgvSKEEAKKRAAKYIELVGLD--ESYLQRS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 166 PHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRG 245
Cdd:PRK13651 163 PFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLN-KQGKTIILVTHDLDNVLEWTKRTIFFKDG 241

                        250
                 ....*....|.
gi 549799341 246 DVVETGTTDDI 256
Cdd:PRK13651 242 KIIKDGDTYDI 252
GguA NF040905
sugar ABC transporter ATP-binding protein;
18-500 8.00e-17

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 83.69  E-value: 8.00e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFrvdGGWKSVvRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLdkktSRI------EGKVMLGGRdll 91
Cdd:NF040905   1 ILEMRGITKTF---PGVKAL-DDVNLSVREGEIHALCGENGAGKS----TLMKVL----SGVyphgsyEGEILFDGE--- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  92 alpEEEMRKVRG---KDISMIFQE----PMTSL--NpIFpIGKQIAEaltvHQDISSSAAKAEVIRLLEKVRIpnaknrf 162
Cdd:NF040905  66 ---VCRFKDIRDseaLGIVIIHQElaliPYLSIaeN-IF-LGNERAK----RGVIDWNETNRRARELLAKVGL------- 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 163 DDYPHQFSG----GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDR 238
Cdd:NF040905 130 DESPDTLVTdigvGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELK-AQGITSIIISHKLNEIRRVADS 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 239 TIVMFRGDVVET------GTTDDIFHRGrhpytrallsavpklgsMKERLLPARFPIIDIKTGEsqpvadvkdtvsggrt 312
Cdd:NF040905 209 ITVLRDGRTIETldcradEVTEDRIIRG-----------------MVGRDLEDRYPERTPKIGE---------------- 255

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFDIRSglfGRKsgavhAVEKVSFDLAEGETLSLVGESGCGK-----STTGRSITRLIeptSGDVMLDGY 387
Cdd:NF040905 256 VVFEVKNWTVYHPLHP---ERK-----VVDDVSLNVRRGEIVGIAGLMGAGRtelamSVFGRSYGRNI---SGTVFKDGK 324

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 388 EVlkldktTLRTMRRSVQ--------------MIFQDP------FASLdPRMSVGTAIMEpFIEHRLGT--KQQAREKAA 445
Cdd:NF040905 325 EV------DVSTVSDAIDaglayvtedrkgygLNLIDDikrnitLANL-GKVSRRGVIDE-NEEIKVAEeyRKKMNIKTP 396

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 446 DLLEKVGlspdmmrrfphEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIK 500
Cdd:NF040905 397 SVFQKVG-----------NLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAK 440
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 344-553 9.24e-17

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 83.64  E-value: 9.24e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRtmrRSVQMIFQDP------------ 411
Cdd:COG4618  351 VSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELG---RHIGYLPQDVelfdgtiaenia 427

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 412 -FASLDPRMSVgtaimepfiehrlgtkqqareKAADLlekVGLSpDMMRRFPHEF-----------SGGQRQRIAIARSL 479
Cdd:COG4618  428 rFGDADPEKVV---------------------AAAKL---AGVH-EMILRLPDGYdtrigeggarlSGGQRQRIGLARAL 482

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 480 MLDPKVIVADEAVSALD-----------VSIKAQvcnllldlqqnlNLAFLFISHDMAVVERVsHRVAVMYLGEIVEIGP 548
Cdd:COG4618  483 YGDPRLVVLDEPNSNLDdegeaalaaaiRALKAR------------GATVVVITHRPSLLAAV-DKLLVLRDGRVQAFGP 549


                 ....*
gi 549799341 549 RAAVF 553
Cdd:COG4618  550 RDEVL 554
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 16-255 9.75e-17

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 83.72  E-value: 9.75e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLttSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPE 95
Cdd:PRK11160 336 QVSLTLNNV--SFTYPDQPQPVLKGLSLQIKAGEKVALLGRTGCGKS----TLLQLLTRAWDPQQGEILLNGQPIADYSE 409

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVrgkdISMIFQEPMtslnpIFpiGKQIAEALTVHQDissSAAKAEVIRLLEKVRIPN---AKNRFD----DYPHQ 168
Cdd:PRK11160 410 AALRQA----ISVVSQRVH-----LF--SATLRDNLLLAAP---NASDEALIEVLQQVGLEKlleDDKGLNawlgEGGRQ 475

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIktLQEEEGMSVLFITHDMGVVAEVsDRTIVMFRGDVV 248
Cdd:PRK11160 476 LSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELL--AEHAQNKTVLMITHRLTGLEQF-DRICVMDNGQII 552


                 ....*..
gi 549799341 249 ETGTTDD 255
Cdd:PRK11160 553 EQGTHQE 559
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
336-496 1.09e-16

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 83.62  E-value: 1.09e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRS-VQMIFQDpfAS 414
Cdd:PRK10535  19 EQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQLRREhFGFIFQR--YH 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 415 LDPRMSVGTAIMEPFIEHRLGTKQQaREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:PRK10535  97 LLSHLTAAQNVEVPAVYAGLERKQR-LLRAQELLQRLGLE-DRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGA 174


                 ..
gi 549799341 495 LD 496
Cdd:PRK10535 175 LD 176
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 341-552 1.40e-16

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 83.17  E-value: 1.40e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKttlRTMRRSVQMIFQDP--FASldpr 418
Cdd:TIGR01842 334 LRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDR---ETFGKHIGYLPQDVelFPG---- 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  419 mSVGTAIMepfiehRLGTKQQARE-----KAADLLEkvglspdMMRRFPHEF-----------SGGQRQRIAIARSLMLD 482
Cdd:TIGR01842 407 -TVAENIA------RFGENADPEKiieaaKLAGVHE-------LILRLPDGYdtvigpggatlSGGQRQRIALARALYGD 472

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  483 PKVIVADEAVSALD-----------VSIKAQVCNLlldlqqnlnlafLFISHDMAVVERVShRVAVMYLGEIVEIGPRAA 551
Cdd:TIGR01842 473 PKLVVLDEPNSNLDeegeqalanaiKALKARGITV------------VVITHRPSLLGCVD-KILVLQDGRIARFGERDE 539


                  .
gi 549799341  552 V 552
Cdd:TIGR01842 540 V 540
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 16-272 1.53e-16

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 79.74  E-value: 1.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTtsFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSI------------MRLLDKKtsriegkv 83
Cdd:COG1119    1 DPLLELRNVT--VRRGG--KTILDDISWTVKPGEHWAILGPNGAGKS-TLLSLitgdlpptygndVRLFGER-------- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  84 mLGGrdllalpeEEMRKVRGK------DISMIFQEPMTSLNPIfpigkqiaeaLT-------VHQDISSsAAKAEVIRLL 150
Cdd:COG1119   68 -RGG--------EDVWELRKRiglvspALQLRFPRDETVLDVV----------LSgffdsigLYREPTD-EQRERARELL 127

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 151 EKVRIPNAKNRfddYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMG 230
Cdd:COG1119  128 ELLGLAHLADR---PFGTLSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVE 204

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 549799341 231 VVAEVSDRTIVMFRGDVVETGTTDDIFhrgrhpyTRALLSAV 272
Cdd:COG1119  205 EIPPGITHVLLLKDGRVVAAGPKEEVL-------TSENLSEA 239
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 39-252 2.19e-16

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 82.56  E-value: 2.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  39 RNMSFEIAPRETVAIVGESGSGKSvtslSIMRLL----DKKtsriEGKVMLGGRDLLALPEEEMRKVrgkdISMIFQEpm 114
Cdd:COG5265  375 KGVSFEVPAGKTVAIVGPSGAGKS----TLARLLfrfyDVT----SGRILIDGQDIRDVTQASLRAA----IGIVPQD-- 440

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 115 TSLnpiF--PIGKQIAEALTvhqdissSAAKAEVIRLLEKVRIpnaknrfddypHQF-------------------SGGM 173
Cdd:COG5265  441 TVL---FndTIAYNIAYGRP-------DASEEEVEAAARAAQI-----------HDFieslpdgydtrvgerglklSGGE 499

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 174 RQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDlikTLQE-EEGMSVLFITHDMGVVAEvSDRTIVMFRGDVVETGT 252
Cdd:COG5265  500 KQRVAIARTLLKNPPILIFDEATSALDSRTERAIQA---ALREvARGRTTLVIAHRLSTIVD-ADEILVLEAGRIVERGT 575
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 338-496 2.52e-16

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 83.15  E-value: 2.52e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  338 VHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKldKTTLRTMRRSVQMIFQDP------ 411
Cdd:PTZ00265  398 VEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDSHNLK--DINLKWWRSKIGVVSQDPllfsns 475

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  412 -----------------------------FASLDPRMS------------VGTAIMEPFIEHRLGTKQQAREKAADLLEK 450
Cdd:PTZ00265  476 iknnikyslyslkdlealsnyynedgndsQENKNKRNScrakcagdlndmSNTTDSNELIEMRKNYQTIKDSEVVDVSKK 555

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341  451 VgLSPDMMRRFPHEF-----------SGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:PTZ00265  556 V-LIHDFVSALPDKYetlvgsnasklSGGQKQRISIARAIIRNPKILILDEATSSLD 611
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 351-496 2.67e-16

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 78.28  E-value: 2.67e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 351 GETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMR-RSVQMIFQDPFasLDPRMSVGTAIMEPF 429
Cdd:PRK10584  36 GETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKLRaKHVGFVFQSFM--LIPTLNALENVELPA 113

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 430 IeHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:PRK10584 114 L-LRGESSRQSRNGAKALLEQLGLG-KRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLD 178
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 8-245 2.88e-16

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 81.97  E-value: 2.88e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   8 MEQTGGSVSpvLSVQNLTTSfrvdgGwksvVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGG 87
Cdd:PRK10762 249 LDKAPGEVR--LKVDNLSGP-----G----VNDVSFTLRKGEILGVSGLMGAGRT----ELMKVLYGALPRTSGYVTLDG 313

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  88 RDLLAL-PEE----------EMRKVRGKDISMIFQEPM--TSLNPIFPIGKQIAealtvHQDisSSAAKAEVIRLLeKVR 154
Cdd:PRK10762 314 HEVVTRsPQDglangivyisEDRKRDGLVLGMSVKENMslTALRYFSRAGGSLK-----HAD--EQQAVSDFIRLF-NIK 385

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 155 IPNAKNRFDDyphqFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAE 234
Cdd:PRK10762 386 TPSMEQAIGL----LSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFK-AEGLSIILVSSEMPEVLG 460

                        250
                 ....*....|.
gi 549799341 235 VSDRTIVMFRG 245
Cdd:PRK10762 461 MSDRILVMHEG 471
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
30-229 3.13e-16

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 78.97  E-value: 3.13e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  30 VDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLAlPEEEmrkvRGkdisMI 109
Cdd:PRK11248   9 ADYGGKPALEDINLTLESGELLVVLGPSGCGKT----TLLNLIAGFVPYQHGSITLDGKPVEG-PGAE----RG----VV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 110 FQEpmTSLNPIFPIGKQIAEALTVhQDISSSAAKAEVIRLLEKVRIPNAKNRFddyPHQFSGGMRQRVMIAMALASKPKL 189
Cdd:PRK11248  76 FQN--EGLLPWRNVQDNVAFGLQL-AGVEKMQRLEIAHQMLKKVGLEGAEKRY---IWQLSGGQRQRVGIARALAANPQL 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 549799341 190 LIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDM 229
Cdd:PRK11248 150 LLLDEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDI 189
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 26-251 3.61e-16

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 77.96  E-value: 3.61e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  26 TSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVmlggrdllalpeeemrKVRGKD 105
Cdd:cd03220   26 LGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKS-TLLRLLAGIYPPDS---GTV----------------TVRGRV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 106 ISMIfqEPMTSLNPifpigkqiaeALTVHQDISSSAA-----KAEVIRLLEKVRIPNAKNRFDDYP-HQFSGGMRQRVMI 179
Cdd:cd03220   86 SSLL--GLGGGFNP----------ELTGRENIYLNGRllglsRKEIDEKIDEIIEFSELGDFIDLPvKTYSSGMKARLAF 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341 180 AMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:cd03220  154 AIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELL-KQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 344-496 4.64e-16

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 81.40  E-value: 4.64e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLdktTLRTMRRSVQMIFQDpfasldprmsvgT 423
Cdd:COG5265  377 VSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDV---TQASLRAAIGIVPQD------------T 441

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 424 AIMEPFIEH-----RLGTKQQAREKAADL--LEkvglspDMMRRFPHEF-----------SGGQRQRIAIARSLMLDPKV 485
Cdd:COG5265  442 VLFNDTIAYniaygRPDASEEEVEAAARAaqIH------DFIESLPDGYdtrvgerglklSGGEKQRVAIARTLLKNPPI 515

                        170
                 ....*....|.
gi 549799341 486 IVADEAVSALD 496
Cdd:COG5265  516 LIFDEATSALD 526
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
37-240 5.23e-16

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 76.50  E-value: 5.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  37 VVRNMSFEIAPRETVAIVGESGSGKSVtslsimrLLdkktsriegKVMLGgrdLLALPEEEMRKVRGKDISMIFQEpmTS 116
Cdd:NF040873   7 VLHGVDLTIPAGSLTAVVGPNGSGKST-------LL---------KVLAG---VLRPTSGTVRRAGGARVAYVPQR--SE 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 117 LNPIFPigkqiaeaLTVHQDIS-------------SSAAKAEVIRLLEKVRIPN-AKNRFDDyphqFSGGMRQRVMIAMA 182
Cdd:NF040873  66 VPDSLP--------LTVRDLVAmgrwarrglwrrlTRDDRAAVDDALERVGLADlAGRQLGE----LSGGQRQRALLAQG 133

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 183 LASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTI 240
Cdd:NF040873 134 LAQEADLLLLDEPTTGLDAESRERIIALLAEEH-ARGATVVVVTHDLELVRRADPCVL 190
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 339-496 5.54e-16

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 77.58  E-value: 5.54e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 339 HAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLdkTTLRTMRRSVQMIFQDpfASLDPR 418
Cdd:cd03218   14 KVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKL--PMHKRARLGIGYLPQE--ASIFRK 89

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 419 MSVGTAIMePFIEHRLGTKQQAREKAADLLEKVGLSPdMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:cd03218   90 LTVEENIL-AVLEIRGLSKKEREEKLEELLEEFHITH-LRKSKASSLSGGERRRVEIARALATNPKFLLLDEPFAGVD 165
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
344-571 5.64e-16

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 78.51  E-value: 5.64e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyEVLKLDKTTLRTMRRSVQMIFQDP-----FASLDPR 418
Cdd:PRK13638  20 LNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQG-KPLDYSKRGLLALRQQVATVFQDPeqqifYTDIDSD 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 419 MSvgtaimepFIEHRLGTKQQAREKAADllekVGLSPDMMRRFPHE----FSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:PRK13638  99 IA--------FSLRNLGVPEAEITRRVD----EALTLVDAQHFRHQpiqcLSHGQKKRVAIAGALVLQARYLLLDEPTAG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 495 LDVSIKAQVCNLLLDLQQNLNLAFLfISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQ--------HPYTKKLMS 566
Cdd:PRK13638 167 LDPAGRTQMIAIIRRIVAQGNHVII-SSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFACTEameqagltQPWLVKLHT 245


                 ....*
gi 549799341 567 AVPVP 571
Cdd:PRK13638 246 QLGLP 250
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 19-272 6.31e-16

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 77.57  E-value: 6.31e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFRVDGgwksvvrnMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLdkktSRIEGKVMLGGRDLLALPEEEM 98
Cdd:COG4138    1 LQLNDVAVAGRLGP--------ISAQVNAGELIHLIGPNGAGKS-TLLARMAGL----LPGQGEILLNGRPLSDWSAAEL 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGkdisMIFQEPMTSLN-PIFpigkqiaEALTVHQD--ISSSAAKAEVIRLLEKVRIPNAKNRfddyP-HQFSGGMR 174
Cdd:COG4138   68 ARHRA----YLSQQQSPPFAmPVF-------QYLALHQPagASSEAVEQLLAQLAEALGLEDKLSR----PlTQLSGGEW 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 175 QRVMIAMALA-------SKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDV 247
Cdd:COG4138  133 QRVRLAAVLLqvwptinPEGQLLLLDEPMNSLDVAQQAALDRLLRELC-QQGITVVMSSHDLNHTLRHADRVWLLKQGKL 211

                        250       260
                 ....*....|....*....|....*
gi 549799341 248 VETGTTDDIFhrgrhpyTRALLSAV 272
Cdd:COG4138  212 VASGETAEVM-------TPENLSEV 229
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 19-242 7.67e-16

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 74.79  E-value: 7.67e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLttSFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGgrdllalpeeem 98
Cdd:cd03221    1 IELENL--SKTYGG--KLLLKDISLTINPGDRIGLVGRNGAGKS----TLLKLIAGELEPDEGIVTWG------------ 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 rkvrgkdismifqepmtslnpifpigkqiaealtvhqdisssaakaevirllEKVRIPnaknrfddYPHQFSGGMRQRVM 178
Cdd:cd03221   61 ----------------------------------------------------STVKIG--------YFEQLSGGEKMRLA 80

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 179 IAMALASKPKLLIADEPTTALDVTiqgQILDLIKTLQEEEGmSVLFITHDMGVVAEVSDRTIVM 242
Cdd:cd03221   81 LAKLLLENPNLLLLDEPTNHLDLE---SIEALEEALKEYPG-TVILVSHDRYFLDQVATKIIEL 140
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
33-295 1.09e-15

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 77.50  E-value: 1.09e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  33 GWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEMRKVRgKDISMIFQE 112
Cdd:PRK11831  18 GNRCIFDNISLTVPRGKITAIMGPSGIGKT----TLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVR-KRMSMLFQS 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 113 P--MTSLNpIFpigKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFddyPHQFSGGMRQRVMIAMALASKPKLL 190
Cdd:PRK11831  93 GalFTDMN-VF---DNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLM---PSELSGGMARRAALARAIALEPDLI 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 191 IADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIfHRGRHPYTRALLS 270
Cdd:PRK11831 166 MFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL-QANPDPRVRQFLD 244

                        250       260
                 ....*....|....*....|....*
gi 549799341 271 AVpklgsmKERLLPARFPIIDIKTG 295
Cdd:PRK11831 245 GI------ADGPVPFRYPAGDYHAD 263
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 18-279 1.13e-15

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 77.47  E-value: 1.13e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRvDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSimrlLDKKTSRIEGKVMLGGRdllALPEEE 97
Cdd:PRK13647   4 IIEVEDLHFRYK-DG--TKALKGLSLSIPEGSKTALLGPNGAGKSTLLLH----LNGIYLPQRGRVKVMGR---EVNAEN 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 MRKVRGKdISMIFQEPMtslNPIFpigkqiaeALTVHQDIS-----SSAAKAEVI-RLLEKVRIPNAKNRFDDYPHQFSG 171
Cdd:PRK13647  74 EKWVRSK-VGLVFQDPD---DQVF--------SSTVWDDVAfgpvnMGLDKDEVErRVEEALKAVRMWDFRDKPPYHLSY 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 172 GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:PRK13647 142 GQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRLH-NQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEG 220

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 549799341 252 -----TTDDIFHRG--RHPYTRALLSAVPKLGSMK 279
Cdd:PRK13647 221 dksllTDEDIVEQAglRLPLVAQIFEDLPELGQSK 255
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 317-544 1.27e-15

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 76.60  E-value: 1.27e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 317 VKDLTTRFDIRS----------GLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDG 386
Cdd:cd03267    3 VSNLSKSYRVYSkepgligslkSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 387 YEVLKLDKTTLR----TMRRSVQMIFQDPfasldprmsvgtaIMEPFIEHRL------GTKQQAREKAADLLEKVGLSPD 456
Cdd:cd03267   83 LVPWKRRKKFLRrigvVFGQKTQLWWDLP-------------VIDSFYLLAAiydlppARFKKRLDELSELLDLEELLDT 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 457 MMRRFPHefsgGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVA 536
Cdd:cd03267  150 PVRQLSL----GQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVL 225


                 ....*...
gi 549799341 537 VMYLGEIV 544
Cdd:cd03267  226 VIDKGRLL 233
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 16-228 1.36e-15

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 76.29  E-value: 1.36e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLttSFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPE 95
Cdd:PRK10247   5 SPLLQLQNV--GYLAGD--AKILNNISFSLRAGEFKLITGPSGCGKS-TLLKIVASLISPTS---GTLLFEGEDISTLKP 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKvrgkDISMIFQEPM-----TSLNPIFP--IGKQIAEaltvhqdisssaaKAEVIRLLEKVRIPNakNRFDDYPHQ 168
Cdd:PRK10247  77 EIYRQ----QVSYCAQTPTlfgdtVYDNLIFPwqIRNQQPD-------------PAIFLDDLERFALPD--TILTKNIAE 137

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHD 228
Cdd:PRK10247 138 LSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHD 197
cbiO PRK13649
energy-coupling factor transporter ATPase;
340-553 1.63e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 77.09  E-value: 1.63e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTT-LRTMRRSVQMIFQDPFASLDPR 418
Cdd:PRK13649  22 ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKdIKQIRKKVGLVFQFPESQLFEE 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 419 MSVGTAIMEPfieHRLG-TKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:PRK13649 102 TVLKDVAFGP---QNFGvSQEEAEALAREKLALVGISESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDP 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 498 SIKAQVCNLLLDLQQNLNLAFLfISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVF 553
Cdd:PRK13649 179 KGRKELMTLFKKLHQSGMTIVL-VTHLMDDVANYADFVYVLEKGKLVLSGKPKDIF 233
NHLM_micro_ABC1 TIGR03796
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ...
 297-496 1.72e-15

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274788 [Multi-domain]  Cd Length: 710  Bit Score: 79.99  E-value: 1.72e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  297 SQPVADVKDTVSGGRTPILSVKDLTTRFDIRSGLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIE 376
Cdd:TIGR03796 451 RNPVDPLLEEPEGSAATSEPPRRLSGYVELRNITFGYSPLEPPLIENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQ 530

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  377 PTSGDVMLDGyevLKLDKTTLRTMRRSVQMIFQDPFasldprMSVGT----------AIMEPFIEhrlgtkqQAREKAAd 446
Cdd:TIGR03796 531 PWSGEILFDG---IPREEIPREVLANSVAMVDQDIF------LFEGTvrdnltlwdpTIPDADLV-------RACKDAA- 593

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341  447 LLEKVGLSPDmmrRFPHE-------FSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:TIGR03796 594 IHDVITSRPG---GYDAElaegganLSGGQRQRLEIARALVRNPSILILDEATSALD 647
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 18-256 1.74e-15

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 79.70  E-value: 1.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   18 VLSVQNLTtsFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEE 97
Cdd:TIGR01842 316 HLSVENVT--IVPPGGKKPTLRGISFSLQAGEALAIIGPSGSGKS----TLARLIVGIWPPTSGSVRLDGADLKQWDRET 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   98 MrkvrGKDISMIFQEPmtslnPIFP--IGKQIA---EALTVHQDISssAAKA----EVIrllekVRIPNAknrFDDY--- 165
Cdd:TIGR01842 390 F----GKHIGYLPQDV-----ELFPgtVAENIArfgENADPEKIIE--AAKLagvhELI-----LRLPDG---YDTVigp 450

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  166 -PHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVsDRTIVMFR 244
Cdd:TIGR01842 451 gGATLSGGQRQRIALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKALK-ARGITVVVITHRPSLLGCV-DKILVLQD 528

                         250
                  ....*....|..
gi 549799341  245 GDVVETGTTDDI 256
Cdd:TIGR01842 529 GRIARFGERDEV 540
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 313-490 1.86e-15

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 76.22  E-value: 1.86e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFDirsglfGRKsgavhAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkl 392
Cdd:COG1137    2 MTLEAENLVKSYG------KRT-----VVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDI--- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 393 dkTTLRTMRRSvQM----------IFQdpfasldpRMSVGTAIMEpFIEHRLGTKQQAREKAADLLEKVGLSPdmMRRFP 462
Cdd:COG1137   68 --THLPMHKRA-RLgigylpqeasIFR--------KLTVEDNILA-VLELRKLSKKEREERLEELLEEFGITH--LRKSK 133

                        170       180
                 ....*....|....*....|....*....
gi 549799341 463 -HEFSGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:COG1137  134 aYSLSGGERRRVEIARALATNPKFILLDE 162
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 313-556 1.90e-15

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 78.73  E-value: 1.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKL 392
Cdd:PRK09536   2 PMIDVSDLSVEF-----------GDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEAL 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 393 DKttlRTMRRSVQMIFQDpfASLDPRMSVGTAIMEPFIEH--RLGTKQQAREKAAD-LLEKVGLSPDMMRRFPhEFSGGQ 469
Cdd:PRK09536  71 SA---RAASRRVASVPQD--TSLSFEFDVRQVVEMGRTPHrsRFDTWTETDRAAVErAMERTGVAQFADRPVT-SLSGGE 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 470 RQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFIsHDMAVVERVSHRVAVMYLGEIVEIGPR 549
Cdd:PRK09536 145 RQRVLLARALAQATPVLLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAI-HDLDLAARYCDELVLLADGRVRAAGPP 223


                 ....*..
gi 549799341 550 AAVFDNP 556
Cdd:PRK09536 224 ADVLTAD 230
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 313-543 2.04e-15

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 74.78  E-value: 2.04e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRfdirsglfgrksgavHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKL 392
Cdd:cd03215    3 PVLEVRGLSVK---------------GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRR 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 393 DKTTLRtmRRSVQMIFQDpfasldpRMSVGTAIMEPFIEHRLgtkqqarekAADLLekvglspdmmrrfphefSGGQRQR 472
Cdd:cd03215   68 SPRDAI--RAGIAYVPED-------RKREGLVLDLSVAENIA---------LSSLL-----------------SGGNQQK 112

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341 473 IAIARSLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEI 543
Cdd:cd03215  113 VVLARWLARDPRVLILDEPTRGVDVGAKAEI-YRLIRELADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
13-256 2.69e-15

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 77.56  E-value: 2.69e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  13 GSVSPV-LSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLggrdlL 91
Cdd:PRK13536  35 GSMSTVaIDLAGVSKSY----GDKAVVNGLSFTVASGECFGLLGPNGAGKS----TIARMILGMTSPDAGKITV-----L 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  92 ALPEEEMRKVRGKDISMIFQepMTSLNPIFpigkQIAEALTVHQ---DISSSAAKAEVIRLLEKVRIpnaKNRFDDYPHQ 168
Cdd:PRK13536 102 GVPVPARARLARARIGVVPQ--FDNLDLEF----TVRENLLVFGryfGMSTREIEAVIPSLLEFARL---ESKADARVSD 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:PRK13536 173 LSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSLL-ARGKTILLTTHFMEEAERLCDRLCVLEAGRKI 251


                 ....*...
gi 549799341 249 ETGTTDDI 256
Cdd:PRK13536 252 AEGRPHAL 259
PTZ00243 PTZ00243
ABC transporter; Provisional
 37-258 3.90e-15

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 79.44  E-value: 3.90e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   37 VVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKktsrIEGKVMLGGRDLLALPEEEMRkvrgKDISMIFQEPMts 116
Cdd:PTZ00243 1325 VLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEV----CGGEIRVNGREIGAYGLRELR----RQFSMIPQDPV-- 1394

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  117 lnpIFPiGkqiaealTVHQDIS--SSAAKAEVIRLLEKV----RIPNAKNRFDDYPHQ----FSGGMRQRVMIAMALASK 186
Cdd:PTZ00243 1395 ---LFD-G-------TVRQNVDpfLEASSAEVWAALELVglreRVASESEGIDSRVLEggsnYSVGQRQLMCMARALLKK 1463

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  187 PKLLI-ADEPTT----ALDVTIQGQILDLIktlqeeEGMSVLFITHDMGVVAEVsDRTIVMFRGDVVETGT-------TD 254
Cdd:PTZ00243 1464 GSGFIlMDEATAnidpALDRQIQATVMSAF------SAYTVITIAHRLHTVAQY-DKIIVMDHGAVAEMGSprelvmnRQ 1536


                  ....
gi 549799341  255 DIFH 258
Cdd:PTZ00243 1537 SIFH 1540
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 42-256 6.48e-15

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 74.97  E-value: 6.48e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  42 SFEIAPRETVAIVGESGSGKSvTSLSIMrlldKKTSRIEGKVMLGGRDLLALPEEEMRKVRGkdiSMIFQEPMTSLNPIF 121
Cdd:PRK03695  16 SAEVRAGEILHLVGPNGAGKS-TLLARM----AGLLPGSGSIQFAGQPLEAWSAAELARHRA---YLSQQQTPPFAMPVF 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 122 pigkqiaEALTVHQ-DISSSAAKAEVI-RLLEKVRIPNAKNRfddYPHQFSGGMRQRVMIAMAL-----ASKP--KLLIA 192
Cdd:PRK03695  88 -------QYLTLHQpDKTRTEAVASALnEVAEALGLDDKLGR---SVNQLSGGEWQRVRLAAVVlqvwpDINPagQLLLL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 193 DEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:PRK03695 158 DEPMNSLDVAQQAALDRLLSELC-QQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEV 220
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 344-568 7.19e-15

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 74.81  E-value: 7.19e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLdKTTLRTMRRSVqmifqdpfasldprMSVGT 423
Cdd:PRK13548  21 VSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADW-SPAELARRRAV--------------LPQHS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 424 AIMEPFIEH---RLG------TKQQAREKAADLLEKVGLSPDMMRRFPhEFSGGQRQRIAIARSLM------LDPKVIVA 488
Cdd:PRK13548  86 SLSFPFTVEevvAMGraphglSRAEDDALVAAALAQVDLAHLAGRDYP-QLSGGEQQRVQLARVLAqlwepdGPPRWLLL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 489 DEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFdnpqhpyTKKLMSAV 568
Cdd:PRK13548 165 DEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAEVL-------TPETLRRV 237
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 341-496 7.49e-15

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 77.54  E-value: 7.49e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVML-DGYEVLkldkttlrtmrrsvqmifqdpFASLDPRM 419
Cdd:COG4178  379 LEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARpAGARVL---------------------FLPQRPYL 437

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 420 SVGT---AIMEPFIEHRLgtkqqAREKAADLLEKVGLSP-----DMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEA 491
Cdd:COG4178  438 PLGTlreALLYPATAEAF-----SDAELREALEAVGLGHlaerlDEEADWDQVLSLGEQQRLAFARLLLHKPDWLFLDEA 512


                 ....*
gi 549799341 492 VSALD 496
Cdd:COG4178  513 TSALD 517
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 314-503 9.05e-15

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 74.77  E-value: 9.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFdirsglfgrKSGAvHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlklD 393
Cdd:PRK13647   4 IIEVEDLHFRY---------KDGT-KALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREV---N 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 KTTLRTMRRSVQMIFQDPfaslDPRMSVGTAIME-PFIEHRLG-TKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQ 471
Cdd:PRK13647  71 AENEKWVRSKVGLVFQDP----DDQVFSSTVWDDvAFGPVNMGlDKDEVERRVEEALKAVRMW-DFRDKPPYHLSYGQKK 145

                        170       180       190
                 ....*....|....*....|....*....|..
gi 549799341 472 RIAIARSLMLDPKVIVADEAVSALDVSIKAQV 503
Cdd:PRK13647 146 RVAIAGVLAMDPDVIVLDEPMAYLDPRGQETL 177
PLN03232 PLN03232
ABC transporter C family member; Provisional
 344-557 9.05e-15

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 78.09  E-value: 9.05e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLrtmRRSVQMIFQDPFasldprMSVGT 423
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDL---RRVLSIIPQSPV------LFSGT 1325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  424 AI--MEPFIEHRLGTKQQAREKA--ADLLEK--VGLSPDMMRRfPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:PLN03232 1326 VRfnIDPFSEHNDADLWEALERAhiKDVIDRnpFGLDAEVSEG-GENFSVGQRQLLSLARALLRRSKILVLDEATASVDV 1404

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  498 SIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERVShRVAVMYLGEIVEigpraavFDNPQ 557
Cdd:PLN03232 1405 RTDSLI--QRTIREEFKSCTMLVIAHRLNTIIDCD-KILVLSSGQVLE-------YDSPQ 1454
PLN03130 PLN03130
ABC transporter C family member; Provisional
 344-501 1.09e-14

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 77.86  E-value: 1.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDkttLRTMRRSVQMIFQDPFasldprMSVGT 423
Cdd:PLN03130 1258 LSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFG---LMDLRKVLGIIPQAPV------LFSGT 1328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  424 AI--MEPFIEHrlgtkqqareKAADL---LEKVGLSpDMMRRFP-----------HEFSGGQRQRIAIARSLMLDPKVIV 487
Cdd:PLN03130 1329 VRfnLDPFNEH----------NDADLwesLERAHLK-DVIRRNSlgldaevseagENFSVGQRQLLSLARALLRRSKILV 1397

                         170
                  ....*....|....
gi 549799341  488 ADEAVSALDVSIKA 501
Cdd:PLN03130 1398 LDEATAAVDVRTDA 1411
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
337-496 1.23e-14

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 74.28  E-value: 1.23e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 337 AVHAVEkvsFDLAEGETLSLVGESGCGKSTTGRSITRLIeptSGD------VMLDGYEVLKLDKTT--LRTMRRSVQMIF 408
Cdd:PRK09984  19 ALHAVD---LNIHHGEMVALLGPSGSGKSTLLRHLSGLI---TGDksagshIELLGRTVQREGRLArdIRKSRANTGYIF 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 409 QDpfASLDPRMSV------GTAIMEPFIEH--RLGTKQQaREKAADLLEKVGlspdmMRRFPHE----FSGGQRQRIAIA 476
Cdd:PRK09984  93 QQ--FNLVNRLSVlenvliGALGSTPFWRTcfSWFTREQ-KQRALQALTRVG-----MVHFAHQrvstLSGGQQQRVAIA 164

                        170       180
                 ....*....|....*....|
gi 549799341 477 RSLMLDPKVIVADEAVSALD 496
Cdd:PRK09984 165 RALMQQAKVILADEPIASLD 184
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 344-553 1.24e-14

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 73.97  E-value: 1.24e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMldgyEVL--KLDKTTLRTMRRS---VQMIFQDPFaslDPR 418
Cdd:COG1119   22 ISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDV----RLFgeRRGGEDVWELRKRiglVSPALQLRF---PRD 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 419 MSV-------GTAIMEPFIEHrlgTKQQaREKAADLLEKVGLSPDMMRRFpHEFSGGQRQRIAIARSLMLDPKVIVADEA 491
Cdd:COG1119   95 ETVldvvlsgFFDSIGLYREP---TDEQ-RERARELLELLGLAHLADRPF-GTLSQGEQRRVLIARALVKDPELLILDEP 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 492 VSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMA-VVERVSHrVAVMYLGEIVEIGPRAAVF 553
Cdd:COG1119  170 TAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEeIPPGITH-VLLLKDGRVVAAGPKEEVL 231
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
17-251 1.39e-14

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 74.84  E-value: 1.39e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTslsiMRLLDKKTSRIEGKVMLGGRDLlalpEE 96
Cdd:PRK13537   6 APIDFRNVEKRY----GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTT----LRMLLGLTHPDAGSISLCGEPV----PS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  97 EMRKVRGKdISMIFQepMTSLNPIFpigkQIAEALTV---HQDISSSAAKAEVIRLLEKVRIpnaKNRFDDYPHQFSGGM 173
Cdd:PRK13537  74 RARHARQR-VGVVPQ--FDNLDPDF----TVRENLLVfgrYFGLSAAAARALVPPLLEFAKL---ENKADAKVGELSGGM 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 174 RQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETG 251
Cdd:PRK13537 144 KRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWERLRSLL-ARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEG 220
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 15-237 1.43e-14

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 73.99  E-value: 1.43e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  15 VSPVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRlldkktsriegkVMLGgrdLLALP 94
Cdd:PRK09544   1 MTSLVSLENVSVSF----GQRRVLSDVSLELKPGKILTLLGPNGAGKS----TLVR------------VVLG---LVAPD 57

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 EEEMRKVRGKDISMIFQEpmTSLNPIFPigkqiaeaLTVHQ--DISSSAAKAEVIRLLEKVripNAKNRFDDYPHQFSGG 172
Cdd:PRK09544  58 EGVIKRNGKLRIGYVPQK--LYLDTTLP--------LTVNRflRLRPGTKKEDILPALKRV---QAGHLIDAPMQKLSGG 124

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 173 MRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSD 237
Cdd:PRK09544 125 ETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTD 189
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
325-490 1.50e-14

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 74.03  E-value: 1.50e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 325 DIRSGLFGRksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSV 404
Cdd:PRK11831   9 DMRGVSFTR--GNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKRM 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 405 QMIFQDpfASLDPRMSVGTAIMEPFIEHRLGTKQQAREKAADLLEKVGL--SPDMMrrfPHEFSGGQRQRIAIARSLMLD 482
Cdd:PRK11831  87 SMLFQS--GALFTDMNVFDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLrgAAKLM---PSELSGGMARRAALARAIALE 161


                 ....*...
gi 549799341 483 PKVIVADE 490
Cdd:PRK11831 162 PDLIMFDE 169
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
39-258 1.86e-14

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 75.45  E-value: 1.86e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  39 RNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLLALPEEEmrkvRGkdISMIFQEpmTSLN 118
Cdd:PRK11000  20 KDINLDIHEGEFVVFVGPSGCGKS-TLLRMIAGLEDITS---GDLFIGEKRMNDVPPAE----RG--VGMVFQS--YALY 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 119 PifpigkqiaeALTVHQDIS-----SSAAKAEVIRLLEKV-RIPNAKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLIA 192
Cdd:PRK11000  88 P----------HLSVAENMSfglklAGAKKEEINQRVNQVaEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 193 DEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFH 258
Cdd:PRK11000 158 DEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYH 223
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 17-255 1.95e-14

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 76.26  E-value: 1.95e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFrvdGGwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGgrdllalpee 96
Cdd:COG0488  314 KVLELEGLSKSY---GD-KTLLDDLSLRIDRGDRIGLIGPNGAGKS----TLLKLLAGELEPDSGTVKLG---------- 375

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  97 emRKVRgkdISMIFQEpMTSLNPifpiGKQIAEALtvhQDISSSAAKAEVIRLLEkvripnaknRF----DD---YPHQF 169
Cdd:COG0488  376 --ETVK---IGYFDQH-QEELDP----DKTVLDEL---RDGAPGGTEQEVRGYLG---------RFlfsgDDafkPVGVL 433

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDV-TIQGqildLIKTLQEEEGmSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:COG0488  434 SGGEKARLALAKLLLSPPNVLLLDEPTNHLDIeTLEA----LEEALDDFPG-TVLLVSHDRYFLDRVATRILEFEDGGVR 508


                 ....*...
gi 549799341 249 E-TGTTDD 255
Cdd:COG0488  509 EyPGGYDD 516
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
8-262 2.18e-14

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 76.30  E-value: 2.18e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   8 MEQTGGSVSPVLS----VQNLTTSFRVDggwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKV 83
Cdd:PRK10790 326 RQQYGNDDRPLQSgridIDNVSFAYRDD---NLVLQNINLSVPSRGFVALVGHTGSGKS----TLASLLMGYYPLTEGEI 398

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  84 MLGGRDLLALPEEEMRkvrgKDISMIFQEPMTSLNPIFpigkqiaEALTVHQDISssaaKAEVIRLLEKVRIPNAKNRFD 163
Cdd:PRK10790 399 RLDGRPLSSLSHSVLR----QGVAMVQQDPVVLADTFL-------ANVTLGRDIS----EEQVWQALETVQLAELARSLP 463

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 164 DYPH--------QFSGGMRQRVMIAMALASKPKLLIADEPTTALDV----TIQgQILDLIKtlqeeEGMSVLFITHDMGV 231
Cdd:PRK10790 464 DGLYtplgeqgnNLSVGQKQLLALARVLVQTPQILILDEATANIDSgteqAIQ-QALAAVR-----EHTTLVVIAHRLST 537

                        250       260       270
                 ....*....|....*....|....*....|..
gi 549799341 232 VAEvSDRTIVMFRGDVVETGTTDDIF-HRGRH 262
Cdd:PRK10790 538 IVE-ADTILVLHRGQAVEQGTHQQLLaAQGRY 568
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
338-537 2.59e-14

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 75.72  E-value: 2.59e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 338 VHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKldKTTLRTMRRSVQMIFQDpfASLDP 417
Cdd:PRK11288  17 VKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRF--ASTTAALAAGVAIIYQE--LHLVP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 418 RMSVGTAIMEPFIEHRLG--TKQQAREKAADLLEKVG--LSPDMMRRfphEFSGGQRQRIAIARSLMLDPKVIVADEAVS 493
Cdd:PRK11288  93 EMTVAENLYLGQLPHKGGivNRRLLNYEAREQLEHLGvdIDPDTPLK---YLSIGQRQMVEIAKALARNARVIAFDEPTS 169

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 549799341 494 ALDvSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAV 537
Cdd:PRK11288 170 SLS-AREIEQLFRVIRELRAEGRVILYVSHRMEEIFALCDAITV 212
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 10-263 2.72e-14

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 75.85  E-value: 2.72e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   10 QTGGSVSPVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSRIEGKVMLGGRd 89
Cdd:TIGR00955  13 RVAQDGSWKQLVSRLRGCFCRERPRKHLLKNVSGVAKPGELLAVMGSSGAGKT-TLMNALAFRSPKGVKGSGSVLLNGM- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   90 llALPEEEMRK----VRGKDI---SMIFQEPMtslnpifpigkQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRF 162
Cdd:TIGR00955  91 --PIDAKEMRAisayVQQDDLfipTLTVREHL-----------MFQAHLRMPRRVTKKEKRERVDEVLQALGLRKCANTR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  163 DDYPHQ---FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHD-MGVVAEVSDR 238
Cdd:TIGR00955 158 IGVPGRvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLA-QKGKTIICTIHQpSSELFELFDK 236

                         250       260
                  ....*....|....*....|....*...
gi 549799341  239 TIVMFRGDVVETGTTD---DIFHRGRHP 263
Cdd:TIGR00955 237 IILMAEGRVAYLGSPDqavPFFSDLGHP 264
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
19-252 3.19e-14

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 75.83  E-value: 3.19e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTtsFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLlalPEEEM 98
Cdd:PRK11176 342 IEFRNVT--FTYPGKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDID----EGEILLDGHDL---RDYTL 412

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRgKDISMIFQEPMtslnpIF--PIGKQIAEALTVH---QDISSSAAKAEVIRLLEKVripnaKNRFDDYPHQ----F 169
Cdd:PRK11176 413 ASLR-NQVALVSQNVH-----LFndTIANNIAYARTEQysrEQIEEAARMAYAMDFINKM-----DNGLDTVIGEngvlL 481

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEgmSVLFITHDMGVVaEVSDRTIVMFRGDVVE 249
Cdd:PRK11176 482 SGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNR--TSLVIAHRLSTI-EKADEILVVEDGEIVE 558


                 ...
gi 549799341 250 TGT 252
Cdd:PRK11176 559 RGT 561
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
17-248 3.29e-14

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 72.60  E-value: 3.29e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPee 96
Cdd:PRK11614   4 VMLSFDKVSAHY----GKIQALHEVSLHINQGEIVTLIGANGAGKT----TLLGTLCGDPRATSGRIVFDGKDITDWQ-- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  97 emrkvrgkdISMIFQEPMTslnpIFPIGKQIAEALTVHQDISSSAAKAEVIRLLEKVR-----IPNAKNRFDDYPHQFSG 171
Cdd:PRK11614  74 ---------TAKIMREAVA----IVPEGRRVFSRMTVEENLAMGGFFAERDQFQERIKwvyelFPRLHERRIQRAGTMSG 140

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 172 GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:PRK11614 141 GEQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLR-EQGMTIFLVEQNANQALKLADRGYVLENGHVV 216
PLN03232 PLN03232
ABC transporter C family member; Provisional
 20-273 4.40e-14

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 75.78  E-value: 4.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   20 SVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLLALPEEEMR 99
Cdd:PLN03232 1234 SIKFEDVHLRYRPGLPPVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELE----KGRIMIDDCDVAKFGLTDLR 1309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  100 KVrgkdISMIFQEPMTSLNPI-FPIgkqiaEALTVHQDisssaakAEVIRLLEKVRIPNA--KNRFD------DYPHQFS 170
Cdd:PLN03232 1310 RV----LSIIPQSPVLFSGTVrFNI-----DPFSEHND-------ADLWEALERAHIKDVidRNPFGldaevsEGGENFS 1373

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  171 GGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILdliKTLQEE-EGMSVLFITHDMGVVAEVsDRTIVMFRGDVVE 249
Cdd:PLN03232 1374 VGQRQLLSLARALLRRSKILVLDEATASVDVRTDSLIQ---RTIREEfKSCTMLVIAHRLNTIIDC-DKILVLSSGQVLE 1449

                         250       260
                  ....*....|....*....|....
gi 549799341  250 TGTTDDIFHRGRHPYTRALLSAVP 273
Cdd:PLN03232 1450 YDSPQELLSRDTSAFFRMVHSTGP 1473
cbiO PRK13644
energy-coupling factor transporter ATPase;
340-556 6.79e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 72.33  E-value: 6.79e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkLDKTTLRTMRRSVQMIFQDPFASLdprm 419
Cdd:PRK13644  17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDT--GDFSKLQGIRKLVGIVFQNPETQF---- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 420 sVGTAIMEPFI---EHRLGTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:PRK13644  91 -VGRTVEEDLAfgpENLCLPPIEIRKRVDRALAEIGLE-KYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLD 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 497 VSiKAQVCNLLLDLQQNLNLAFLFISHDMAVVErVSHRVAVMYLGEIVEIGPRAAVFDNP 556
Cdd:PRK13644 169 PD-SGIAVLERIKKLHEKGKTIVYITHNLEELH-DADRIIVMDRGKIVLEGEPENVLSDV 226
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 18-251 7.92e-14

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 71.15  E-value: 7.92e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVtslsimrLLDKKTSRIEGKVMLGGRDLLAlpEEE 97
Cdd:cd03234    3 VLPWWDVGLKAKNWNKYARILNDVSLHVESGQVMAILGSSGSGKTT-------LLDAISGRVEGGGTTSGQILFN--GQP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 MRKVRGKD-ISMIFQEpmtslnpifpigKQIAEALTVHQDI-----------SSSAAKAEV-----IRLLEKVRIPNAKN 160
Cdd:cd03234   74 RKPDQFQKcVAYVRQD------------DILLPGLTVRETLtytailrlprkSSDAIRKKRvedvlLRDLALTRIGGNLV 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 161 RfddyphQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQgqiLDLIKTLQE--EEGMSVLFITHDMGV-VAEVSD 237
Cdd:cd03234  142 K------GISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFTA---LNLVSTLSQlaRRNRIVILTIHQPRSdLFRLFD 212

                        250
                 ....*....|....
gi 549799341 238 RTIVMFRGDVVETG 251
Cdd:cd03234  213 RILLLSSGEIVYSG 226
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
310-552 8.03e-14

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 72.53  E-value: 8.03e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 310 GRTPILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEV 389
Cdd:PRK13537   3 MSVAPIDFRNVEKRY-----------GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPV 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 390 lkldKTTLRTMRRSVQMIFQdpFASLDPRMSVGTAIMePFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRFpHEFSGGQ 469
Cdd:PRK13537  72 ----PSRARHARQRVGVVPQ--FDNLDPDFTVRENLL-VFGRYFGLSAAAARALVPPLLEFAKLENKADAKV-GELSGGM 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 470 RQRIAIARSLMLDPKVIVADEAVSALDVSIKaQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLG-EIVEIGP 548
Cdd:PRK13537 144 KRRLTLARALVNDPDVLVLDEPTTGLDPQAR-HLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGrKIAEGAP 222


                 ....
gi 549799341 549 RAAV 552
Cdd:PRK13537 223 HALI 226
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 314-496 8.74e-14

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 71.66  E-value: 8.74e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFDIRSGLfgrksgAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkld 393
Cdd:COG1101    1 MLELKNLSKTFNPGTVN------EKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDV---- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 kTTLRTMRRSvQMI---FQDPFASLDPRMSvgtaimepfIEH--------------RLGTKQQAREKAADLLEKVGLS-P 455
Cdd:COG1101   71 -TKLPEYKRA-KYIgrvFQDPMMGTAPSMT---------IEEnlalayrrgkrrglRRGLTKKRRELFRELLATLGLGlE 139

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 549799341 456 DMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:COG1101  140 NRLDTKVGLLSGGQRQALSLLMATLTKPKLLLLDEHTAALD 180
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 19-227 8.81e-14

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 69.49  E-value: 8.81e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTtsFRVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLdkktSRI----EGKV-MLGGRDLLAL 93
Cdd:cd03223    1 IELENLS--LATPDG-RVLLKDLSFEIKPGDRLLITGPSGTGKS----SLFRAL----AGLwpwgSGRIgMPEGEDLLFL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  94 PEEemrkvrgkdismifqepmtslnPIFPIGkqiaealtvhqdisssaakaeviRLLEKVRipnaknrfddYP--HQFSG 171
Cdd:cd03223   70 PQR----------------------PYLPLG-----------------------TLREQLI----------YPwdDVLSG 94

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 172 GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKtlqeEEGMSVLFITH 227
Cdd:cd03223   95 GEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQLLK----ELGITVISVGH 146
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
341-498 1.03e-13

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 71.20  E-value: 1.03e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLdktTLRTMRRSVQMIFQDPfasLDPRms 420
Cdd:PRK11231  18 LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISML---SSRQLARRLALLPQHH---LTPE-- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 421 vGTAIME-------PFIEH--RLGTKQQAREKAAdlLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEA 491
Cdd:PRK11231  90 -GITVRElvaygrsPWLSLwgRLSAEDNARVNQA--MEQTRIN-HLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEP 165


                 ....*..
gi 549799341 492 VSALDVS 498
Cdd:PRK11231 166 TTYLDIN 172
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 4-256 1.36e-13

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 73.73  E-value: 1.36e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   4 AATSMEQTGGSVSPV-LSVQNLTTsFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSrIEGK 82
Cdd:PRK11174 334 HPQQGEKELASNDPVtIEAEDLEI-LSPDG--KTLAGPLNFTLPAGQRIALVGPSGAGKT----SLLNALLGFLP-YQGS 405

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  83 VMLGGRDLLALPEEEMRKvrgkDISMIFQepmtslNPIFPIGkqiaealTVHQDIS---SSAAKAEVIRLLEKVRIPNAK 159
Cdd:PRK11174 406 LKINGIELRELDPESWRK----HLSWVGQ------NPQLPHG-------TLRDNVLlgnPDASDEQLQQALENAWVSEFL 468

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 160 NRFD---DYPHQ-----FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILdliKTLQEE-EGMSVLFITHDMG 230
Cdd:PRK11174 469 PLLPqglDTPIGdqaagLSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSEQLVM---QALNAAsRRQTTLMVTHQLE 545

                        250       260
                 ....*....|....*....|....*.
gi 549799341 231 VVAEVsDRTIVMFRGDVVETGTTDDI 256
Cdd:PRK11174 546 DLAQW-DQIWVMQDGQIVQQGDYAEL 570
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 19-265 2.76e-13

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 70.32  E-value: 2.76e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLttSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKktsrIEGKVMLGGRDLLALPEEEM 98
Cdd:cd03288   20 IKIHDL--CVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDI----FDGKIVIDGIDISKLPLHTL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKvrgkDISMIFQEPMTslnpifpigkqIAEALTVHQDissSAAKAEVIRLLEKVRIPNAKNRFDDYP-----------H 167
Cdd:cd03288   94 RS----RLSIILQDPIL-----------FSGSIRFNLD---PECKCTDDRLWEALEIAQLKNMVKSLPggldavvteggE 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 168 QFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEgmSVLFITHDMGVVAEvSDRTIVMFRGDV 247
Cdd:cd03288  156 NFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADR--TVVTIAHRVSTILD-ADLVLVLSRGIL 232

                        250
                 ....*....|....*...
gi 549799341 248 VETGTTDDIFHRGRHPYT 265
Cdd:cd03288  233 VECDTPENLLAQEDGVFA 250
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
16-550 3.56e-13

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 72.25  E-value: 3.56e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFRvdgGWKSVvRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGrdllalpe 95
Cdd:PRK11288   2 SPYLSFDGIGKTFP---GVKAL-DDISFDCRAGQVHALMGENGAGKS-TLLKILSGNYQPDA---GSILIDG-------- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGKD-----ISMIFQE----P-MTslnpifpigkqIAEALTVHQ------DISSSAAKAEVIRLLEKVRI---P 156
Cdd:PRK11288  66 QEMRFASTTAalaagVAIIYQElhlvPeMT-----------VAENLYLGQlphkggIVNRRLLNYEAREQLEHLGVdidP 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 157 NAKNRFddyphqFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVS 236
Cdd:PRK11288 135 DTPLKY------LSIGQRQMVEIAKALARNARVIAFDEPTSSLSAREIEQLFRVIRELR-AEGRVILYVSHRMEEIFALC 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 237 DRTIVmfrgdvvetgttddiFHRGRHPYTRALLSAVPK---LGSMKERllparfPIIDIKTGESQPVADVKDTVSGGRTP 313
Cdd:PRK11288 208 DAITV---------------FKDGRYVATFDDMAQVDRdqlVQAMVGR------EIGDIYGYRPRPLGEVRLRLDGLKGP 266

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSvkdlttrfdirsglfgrksgavhavEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyEVLKLd 393
Cdd:PRK11288 267 GLR-------------------------EPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDG-KPIDI- 319

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 KTTLRTMRRSVQMIFQD-------PFAS-------------------LDPRMSVGTAimEPFIEhRLGTKQQAREKAADL 447
Cdd:PRK11288 320 RSPRDAIRAGIMLCPEDrkaegiiPVHSvadninisarrhhlragclINNRWEAENA--DRFIR-SLNIKTPSREQLIMN 396

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 448 LekvglspdmmrrfphefSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAV 527
Cdd:PRK11288 397 L-----------------SGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEI-YNVIYELAAQGVAVLFVSSDLPE 458

                        570       580
                 ....*....|....*....|...
gi 549799341 528 VERVSHRVAVMYLGEIVEIGPRA 550
Cdd:PRK11288 459 VLGVADRIVVMREGRIAGELARE 481
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 315-498 3.88e-13

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 68.54  E-value: 3.88e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  315 LSVKDLTTRFDIRSglfgrksgavhAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDK 394
Cdd:TIGR01189   1 LAARNLACSRGERM-----------LFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRD 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  395 TTLRtmrrsvQMIFQDPFASLDPRMSVGTAIMepFIEHRLGTKQQAREkaaDLLEKVGLSpDMMRRFPHEFSGGQRQRIA 474
Cdd:TIGR01189  70 EPHE------NILYLGHLPGLKPELSALENLH--FWAAIHGGAQRTIE---DALAAVGLT-GFEDLPAAQLSAGQQRRLA 137

                         170       180
                  ....*....|....*....|....
gi 549799341  475 IARSLMLDPKVIVADEAVSALDVS 498
Cdd:TIGR01189 138 LARLWLSRRPLWILDEPTTALDKA 161
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 17-252 3.97e-13

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 73.12  E-value: 3.97e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    17 PVLSVQNLTTSFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDLlalpEE 96
Cdd:TIGR01257  927 PGVCVKNLVKIFEPSG--RPAVDRLNITFYENQITAFLGHNGAGKT-TTLSILTGLLPPTS---GTVLVGGKDI----ET 996

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    97 EMRKVRgKDISMIFQEpmtslNPIFPiGKQIAEALTVHQDI---SSSAAKAEVIRLLEKVRIPNAKNrfdDYPHQFSGGM 173
Cdd:TIGR01257  997 NLDAVR-QSLGMCPQH-----NILFH-HLTVAEHILFYAQLkgrSWEEAQLEMEAMLEDTGLHHKRN---EEAQDLSGGM 1066

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341   174 RQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIktLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGT 252
Cdd:TIGR01257 1067 QRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGT 1143
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
16-257 4.12e-13

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 69.91  E-value: 4.12e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSFRvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMrlldkktsrieGKVMLGGRDLLALPE 95
Cdd:PRK15056   4 QAGIVVNDVTVTWR---NGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALM-----------GFVRLASGKISILGQ 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGKDISMIFQEPMTSLNpiFPIgkqIAEALTV-----HQD---ISSSAAKAEVIRLLEKVRIPNAKNRfddYPH 167
Cdd:PRK15056  70 PTRQALQKNLVAYVPQSEEVDWS--FPV---LVEDVVMmgrygHMGwlrRAKKRDRQIVTAALARVDMVEFRHR---QIG 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 168 QFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTiVMFRGDV 247
Cdd:PRK15056 142 ELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELR-DEGKTMLVSTHNLGSVTEFCDYT-VMVKGTV 219

                        250
                 ....*....|
gi 549799341 248 VETGTTDDIF 257
Cdd:PRK15056 220 LASGPTETTF 229
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
18-234 4.88e-13

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 68.29  E-value: 4.88e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSfRvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKsvTSLsiMRLLDKKTSRIEGKVMLGGRDLLALPEEe 97
Cdd:PRK13538   1 MLEARNLACE-R---DERILFSGLSFTLNAGELVQIEGPNGAGK--TSL--LRILAGLARPDAGEVLWQGEPIRRQRDE- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 mrkvrgkdismiFQEPMTSLnpifpiGKQ--IAEALTVH------QDISSSAAKAEVIRLLEKVRIpnakNRFDDYP-HQ 168
Cdd:PRK13538  72 ------------YHQDLLYL------GHQpgIKTELTALenlrfyQRLHGPGDDEALWEALAQVGL----AGFEDVPvRQ 129

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341 169 FSGGMRQRVmiamALA----SKPKLLIADEPTTALDVtiQGqILDLIKTLQE--EEGMSVLFITH-DMGVVAE 234
Cdd:PRK13538 130 LSAGQQRRV----ALArlwlTRAPLWILDEPFTAIDK--QG-VARLEALLAQhaEQGGMVILTTHqDLPVASD 195
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
340-496 5.24e-13

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 71.67  E-value: 5.24e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMldgYEVLKLDKTTLRTMRRSVQMIFQDPFASLDprm 419
Cdd:PRK10789 330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIR---FHDIPLTKLQLDSWRSRLAVVSQTPFLFSD--- 403

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 420 SVGTAIMEpfieHRLGTKQQAREKAADLlekVGLSPDMMRrFPHEF-----------SGGQRQRIAIARSLMLDPKVIVA 488
Cdd:PRK10789 404 TVANNIAL----GRPDATQQEIEHVARL---ASVHDDILR-LPQGYdtevgergvmlSGGQKQRISIARALLLNAEILIL 475


                 ....*...
gi 549799341 489 DEAVSALD 496
Cdd:PRK10789 476 DDALSAVD 483
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 37-257 5.32e-13

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 72.37  E-value: 5.32e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   37 VVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRI------------------------------------- 79
Cdd:PTZ00265 1183 IYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFYDLKNDHHivfknehtndmtneqdyqgdeeqnvgmknvnefsltk 1262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   80 -------------EGKVMLGGRDLLALPEEEMRKVrgkdISMIFQEPM---TSLNPIFPIGKQIAealtVHQDISSSAAK 143
Cdd:PTZ00265 1263 eggsgedstvfknSGKILLDGVDICDYNLKDLRNL----FSIVSQEPMlfnMSIYENIKFGKEDA----TREDVKRACKF 1334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  144 AEVIRLLEKVripnaKNRFDD----YPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEG 219
Cdd:PTZ00265 1335 AAIDEFIESL-----PNKYDTnvgpYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKAD 1409

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 549799341  220 MSVLFITHDMGVVAEvSDRTIVMFRGD-----VVETGTTDDIF 257
Cdd:PTZ00265 1410 KTIITIAHRIASIKR-SDKIVVFNNPDrtgsfVQAHGTHEELL 1451
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
19-259 5.35e-13

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 70.64  E-value: 5.35e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrvDGGwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRL---LDKKTSrieGKVMLGGRDLLAL-P 94
Cdd:PRK11650   4 LKLQAVRKSY--DGK-TQVIKGIDLDVADGEFIVLVGPSGCGKS----TLLRMvagLERITS---GEIWIGGRVVNELeP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  95 EEemrkvrgKDISMIFQEpmTSLNPifpigkqiaeALTVHQDISSS-----AAKAEVIRLLEKV-RIPNAKNRFDDYPHQ 168
Cdd:PRK11650  74 AD-------RDIAMVFQN--YALYP----------HMSVRENMAYGlkirgMPKAEIEERVAEAaRILELEPLLDRKPRE 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:PRK11650 135 LSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAE 214

                        250
                 ....*....|.
gi 549799341 249 ETGTTDDIFHR 259
Cdd:PRK11650 215 QIGTPVEVYEK 225
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 19-232 5.52e-13

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 68.15  E-value: 5.52e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   19 LSVQNLTTSfRvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLlalpeEEM 98
Cdd:TIGR01189   1 LAARNLACS-R---GERMLFEGLSFTLNAGEALQVTGPNGIGKT----TLLRILAGLLRPDSGEVRWNGTPL-----AEQ 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   99 RKVRGKDISMIFQEPmtSLNPIFpigkQIAEALTVHQDISSSAAKAeVIRLLEKVRIpnakNRFDDYP-HQFSGGMRQRV 177
Cdd:TIGR01189  68 RDEPHENILYLGHLP--GLKPEL----SALENLHFWAAIHGGAQRT-IEDALAAVGL----TGFEDLPaAQLSAGQQRRL 136

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 549799341  178 MIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVV 232
Cdd:TIGR01189 137 ALARLWLSRRPLWILDEPTTALDKAGVALLAGLLRAHLARGGIVLLTTHQDLGLV 191
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 314-548 9.79e-13

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 69.35  E-value: 9.79e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 314 ILSVKDLTTRFDIRS----------GLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVM 383
Cdd:COG4586    1 IIEVENLSKTYRVYEkepglkgalkGLFRREYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 384 LDGYEVLKLDKTTLRTM-----RRSvQMIF----QDPFASLdprmsvgTAImepfieHRLgTKQQAREKAADLLEKVGLS 454
Cdd:COG4586   81 VLGYVPFKRRKEFARRIgvvfgQRS-QLWWdlpaIDSFRLL-------KAI------YRI-PDAEYKKRLDELVELLDLG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 455 pDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVcnllldlqqnlnLAFL------------FIS 522
Cdd:COG4586  146 -ELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAI------------REFLkeynrergttilLTS 212

                        250       260
                 ....*....|....*....|....*.
gi 549799341 523 HDMAVVERVSHRVAVMYLGEIVEIGP 548
Cdd:COG4586  213 HDMDDIEALCDRVIVIDHGRIIYDGS 238
hmuV PRK13547
heme ABC transporter ATP-binding protein;
18-256 1.18e-12

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 68.70  E-value: 1.18e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVdggwKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLL--------DKKTSRIEGKVMLGGRD 89
Cdd:PRK13547   1 MLTADHLHVARRH----RAILRDLSLRIEPGRVTALLGRNGAGKS----TLLKALagdltgggAPRGARVTGDVTLNGEP 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  90 LLALPEEEMRKVRgkdiSMIFQEPMT----SLNPIFPIGK----QIAEALTVH-QDISSSA-AKAEVIRLLEKvripnak 159
Cdd:PRK13547  73 LAAIDAPRLARLR----AVLPQAAQPafafSAREIVLLGRyphaRRAGALTHRdGEIAWQAlALAGATALVGR------- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 160 nrfdDYPhQFSGGMRQRVMIAMALA---------SKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMG 230
Cdd:PRK13547 142 ----DVT-TLSGGELARVQFARVLAqlwpphdaaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPN 216

                        250       260
                 ....*....|....*....|....*.
gi 549799341 231 VVAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:PRK13547 217 LAARHADRIAMLADGAIVAHGAPADV 242
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
349-560 1.44e-12

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 69.13  E-value: 1.44e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 349 AEGETlSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTT-LRTMRRSVQMIFQDpfASLDPRMSVGTAIme 427
Cdd:PRK11144  23 AQGIT-AIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGIcLPPEKRRIGYVFQD--ARLFPHYKVRGNL-- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 428 pfiehRLGTKQQAREKAADLLEKVGLSPdMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLL 507
Cdd:PRK11144  98 -----RYGMAKSMVAQFDKIVALLGIEP-LLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYL 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 549799341 508 LDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFDNPQ-HPY 560
Cdd:PRK11144 172 ERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASSAmRPW 225
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 35-497 2.20e-12

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 69.96  E-value: 2.20e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   35 KSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKtsrIEGKVMLG-GRDLLALPEE----EMRKVRG------ 103
Cdd:TIGR03719  18 KEILKDISLSFFPGAKIGVLGLNGAGKS-TLLRIMAGVDKD---FNGEARPQpGIKVGYLPQEpqldPTKTVREnveegv 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  104 ----------KDISMIFQEPMTSLNpifpigkQIAEALTVHQDISSSAAKAEVIRLLEKV----RIPNaknrfDDYP-HQ 168
Cdd:TIGR03719  94 aeikdaldrfNEISAKYAEPDADFD-------KLAAEQAELQEIIDAADAWDLDSQLEIAmdalRCPP-----WDADvTK 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTiqgQILDLIKTLQEEEGmSVLFITHD-------MGVVAEVsDR-TI 240
Cdd:TIGR03719 162 LSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAE---SVAWLERHLQEYPG-TVVAVTHDryfldnvAGWILEL-DRgRG 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  241 VMFRGD-----------VVETGTTDDIFHR--------------GRHPYTRALLSAVPKLGSmKERLLPARFPIIDIKTG 295
Cdd:TIGR03719 237 IPWEGNysswleqkqkrLEQEEKEESARQKtlkrelewvrqspkGRQAKSKARLARYEELLS-QEFQKRNETAEIYIPPG 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  296 ESqpvadVKDTVsggrtpiLSVKDLTTRFDIRSgLFgrksgavhavEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLI 375
Cdd:TIGR03719 316 PR-----LGDKV-------IEAENLTKAFGDKL-LI----------DDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQE 372

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  376 EPTSGDVmldgyevlkldkttlrTMRRSVQMIFQDPF-ASLDPRMSVGTAIMEPFIEHRLGTKQ-QARE-------KAAD 446
Cdd:TIGR03719 373 QPDSGTI----------------EIGETVKLAYVDQSrDALDPNKTVWEEISGGLDIIKLGKREiPSRAyvgrfnfKGSD 436

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 549799341  447 LLEKVGlspdmmrrfphEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:TIGR03719 437 QQKKVG-----------QLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDV 476
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 18-255 2.43e-12

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 69.47  E-value: 2.43e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   18 VLSVQNLTtSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTslsIMRLLDKKTSRIEGKVMLGGRDL-LALPEE 96
Cdd:TIGR02633 257 ILEARNLT-CWDVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTEL---VQALFGAYPGKFEGNVFINGKPVdIRNPAQ 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   97 EMRKvrgkDISMIFQE-PMTSLNPIFPIGKQIA-EALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFDDYP-HQFSGGM 173
Cdd:TIGR02633 333 AIRA----GIAMVPEDrKRHGIVPILGVGKNITlSVLKSFCFKMRIDAAAELQIIGSAIQRLKVKTASPFLPiGRLSGGN 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  174 RQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVM----FRGDVVE 249
Cdd:TIGR02633 409 QQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLA-QEGVAIIVVSSELAEVLGLSDRVLVIgegkLKGDFVN 487


                  ....*.
gi 549799341  250 TGTTDD 255
Cdd:TIGR02633 488 HALTQE 493
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 344-496 2.89e-12

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 66.53  E-value: 2.89e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEP---TSGDVMLDGYEVLKldkttlRTMRRSVQMIFQDPFasLDPRMS 420
Cdd:cd03234   26 VSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGggtTSGQILFNGQPRKP------DQFQKCVAYVRQDDI--LLPGLT 97

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 421 VGTAI--MEPFIEHRLGTKQQAREKAADLLEK-VGLSPDMMRRFPHeFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:cd03234   98 VRETLtyTAILRLPRKSSDAIRKKRVEDVLLRdLALTRIGGNLVKG-ISGGERRRVSIAVQLLWDPKVLILDEPTSGLD 175
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 42-496 3.62e-12

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 68.89  E-value: 3.62e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  42 SFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDLLALPEEEMRKVrgkdISMIFQEPMTSLnpIF 121
Cdd:PRK10938  23 SLTLNAGDSWAFVGANGSGKS----ALARALAGELPLLSGERQSQFSHITRLSFEQLQKL----VSDEWQRNNTDM--LS 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 122 P----IGKQIAEaltVHQDISSSAAKAEviRLLEKVRIPNAKNRFDDYphqFSGGMRQRVMIAMALASKPKLLIADEPTT 197
Cdd:PRK10938  93 PgeddTGRTTAE---IIQDEVKDPARCE--QLAQQFGITALLDRRFKY---LSTGETRKTLLCQALMSEPDLLILDEPFD 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 198 ALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFHRgrhpytrallSAVPKLgS 277
Cdd:PRK10938 165 GLDVASRQQLAELLASLH-QSGITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEILQQ----------ALVAQL-A 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 278 MKERL----LPARF-PIIDIKTGESQPVADVKD-TVSGGRTPILSvkdlttrfdirsglfgrksgavhaveKVSFDLAEG 351
Cdd:PRK10938 233 HSEQLegvqLPEPDePSARHALPANEPRIVLNNgVVSYNDRPILH--------------------------NLSWQVNPG 286

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 352 ETLSLVGESGCGKSTTGRSITrlieptsGDvMLDGYEvlklDKTTLRTMRR-SVQMIFQDP----FAS----LDPRMS-- 420
Cdd:PRK10938 287 EHWQIVGPNGAGKSTLLSLIT-------GD-HPQGYS----NDLTLFGRRRgSGETIWDIKkhigYVSsslhLDYRVSts 354

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 421 VGTAIMEPFIEhRLGTKQQA----REKAADLLEKVGLSPDMMRRFPHEFSGGQrQRIA-IARSLMLDPKVIVADEAVSAL 495
Cdd:PRK10938 355 VRNVILSGFFD-SIGIYQAVsdrqQKLAQQWLDILGIDKRTADAPFHSLSWGQ-QRLAlIVRALVKHPTLLILDEPLQGL 432


                 .
gi 549799341 496 D 496
Cdd:PRK10938 433 D 433
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 341-496 4.72e-12

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 66.07  E-value: 4.72e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTlrTMRRSVQMIFQDpfASLDPRMS 420
Cdd:PRK10895  19 VEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHA--RARRGIGYLPQE--ASIFRRLS 94

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341 421 VGTAIMEPF-IEHRLgTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:PRK10895  95 VYDNLMAVLqIRDDL-SAEQREDRANELMEEFHIE-HLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVD 169
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 37-260 5.42e-12

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 69.20  E-value: 5.42e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    37 VVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKtsriEGKVMLGGRDLLALPEEEMRKvrgkDISMIFQEPMTs 116
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESA----EGEIIIDGLNIAKIGLHDLRF----KITIIPQDPVL- 1371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   117 lnpifpigkqIAEALTVHQDISSSAAKAEVIRLLEKVRIPN-AKNRFDDYPHQ-------FSGGMRQRVMIAMALASKPK 188
Cdd:TIGR00957 1372 ----------FSGSLRMNLDPFSQYSDEEVWWALELAHLKTfVSALPDKLDHEcaeggenLSVGQRQLVCLARALLRKTK 1441

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549799341   189 LLIADEPTTALDVTIQGQILDLIKTlqEEEGMSVLFITHDMGVVAEVSdRTIVMFRGDVVETGTTDDIF-HRG 260
Cdd:TIGR00957 1442 ILVLDEATAAVDLETDNLIQSTIRT--QFEDCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNLLqQRG 1511
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
136-256 6.18e-12

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 67.45  E-value: 6.18e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 136 DISSSAAKAEVIRLLEKVRIPNAKNRfddYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQ 215
Cdd:NF000106 115 DLSRKDARARADELLERFSLTEAAGR---AAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMV 191

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 549799341 216 eEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:NF000106 192 -RDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 19-235 7.40e-12

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 64.82  E-value: 7.40e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTtsfrVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRdllalPEEEM 98
Cdd:cd03231    1 LEADELT----CERDGRALFSGLSFTLAAGEALQVTGPNGSGKT----TLLRILAGLSPPLAGRVLLNGG-----PLDFQ 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGKDISMIFQEP--MTSLNPIfpigkqiaEALTVHQDISSSAAkaeVIRLLEKVRIpnakNRFDDYP-HQFSGGMRQ 175
Cdd:cd03231   68 RDSIARGLLYLGHAPgiKTTLSVL--------ENLRFWHADHSDEQ---VEEALARVGL----NGFEDRPvAQLSAGQQR 132

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEV 235
Cdd:cd03231  133 RVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAGHCARGGMVVLTTHQDLGLSEAG 192
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 18-253 8.05e-12

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 68.03  E-value: 8.05e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTtSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKsvTSLsIMRLLDKKTSRIEGKVMLGGRDL-LALPEE 96
Cdd:PRK13549 259 ILEVRNLT-AWDPVNPHIKRVDDVSFSLRRGEILGIAGLVGAGR--TEL-VQCLFGAYPGRWEGEIFIDGKPVkIRNPQQ 334

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  97 EMRKvrgkDISMIFQE-PMTSLNPIFPIGKQIAeaLTVHQDISS----------SAAKAEVIRLleKVRIPNAKNRFDdy 165
Cdd:PRK13549 335 AIAQ----GIAMVPEDrKRDGIVPVMGVGKNIT--LAALDRFTGgsriddaaelKTILESIQRL--KVKTASPELAIA-- 404

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 166 phQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVM--- 242
Cdd:PRK13549 405 --RLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLV-QQGVAIIVISSELPEVLGLSDRVLVMheg 481

                        250
                 ....*....|..
gi 549799341 243 -FRGDVVETGTT 253
Cdd:PRK13549 482 kLKGDLINHNLT 493
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 316-496 1.18e-11

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 64.59  E-value: 1.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 316 SVKDLTTRFDIRSGLFGRKSGAV--HAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEptsgdvmldgyevlkld 393
Cdd:COG2401   19 SVLDLSERVAIVLEAFGVELRVVerYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALK----------------- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 kttlrtmRRSVQMIFQDPFASLDPRMSVgtaimepfIEH--RLGTKQQAREkaadLLEKVGLS-PDMMRRFPHEFSGGQR 470
Cdd:COG2401   82 -------GTPVAGCVDVPDNQFGREASL--------IDAigRKGDFKDAVE----LLNAVGLSdAVLWLRRFKELSTGQK 142

                        170       180
                 ....*....|....*....|....*.
gi 549799341 471 QRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:COG2401  143 FRFRLALLLAERPKLLVIDEFCSHLD 168
oligo_HPY pfam08352
Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found ...
 544-580 1.19e-11

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found towards the C-terminus of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid.


Pssm-ID: 400588 [Multi-domain]  Cd Length: 65  Bit Score: 60.11  E-value: 1.19e-11
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 549799341  544 VEIGPRAAVFDNPQHPYTKKLMSAVPVPDPARRQIKR 580
Cdd:pfam08352   1 VEEGPTDDILENPLHPYTRALLNSVPRLDPPKRPLYT 37
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
52-258 1.34e-11

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 66.44  E-value: 1.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  52 AIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGRDL------LALPEEEMRkvrgkdISMIFQEPMtslnpIFP--- 122
Cdd:PRK11144  28 AIFGRSGAGKT----SLINAISGLTRPQKGRIVLNGRVLfdaekgICLPPEKRR------IGYVFQDAR-----LFPhyk 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 123 ------IGkqIAEALTVHQDisssaakaEVIRLL--EKVripnaknrFDDYPHQFSGGMRQRVMIAMALASKPKLLIADE 194
Cdd:PRK11144  93 vrgnlrYG--MAKSMVAQFD--------KIVALLgiEPL--------LDRYPGSLSGGEKQRVAIGRALLTAPELLLMDE 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 195 PTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDIFH 258
Cdd:PRK11144 155 PLASLDLPRKRELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWA 218
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 329-503 1.60e-11

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 66.99  E-value: 1.60e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  329 GLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEP---TSGDVMLDGYEVlkldktTLRTMRRSVQ 405
Cdd:TIGR00955  29 GCFCRERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKgvkGSGSVLLNGMPI------DAKEMRAISA 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  406 MIFQDPFasLDPRMSVGTAIMepFIEH-RLG---TKQQAREKAADLLEKVGL---------SPDMMRrfphEFSGGQRQR 472
Cdd:TIGR00955 103 YVQQDDL--FIPTLTVREHLM--FQAHlRMPrrvTKKEKRERVDEVLQALGLrkcantrigVPGRVK----GLSGGERKR 174

                         170       180       190
                  ....*....|....*....|....*....|.
gi 549799341  473 IAIARSLMLDPKVIVADEAVSALDVSIKAQV 503
Cdd:TIGR00955 175 LAFASELLTDPPLLFCDEPTSGLDSFMAYSV 205
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
143-537 2.18e-11

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 66.76  E-value: 2.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 143 KAEVIRLLEKVripNAKNRFDDYPHQF-------------SGGMRQRVMIAMALASKPKLLIADEPTTALDVtiqGQILD 209
Cdd:PRK13409 177 KGKVRELLKKV---DERGKLDEVVERLglenildrdiselSGGELQRVAIAAALLRDADFYFFDEPTSYLDI---RQRLN 250

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 210 LIKTLQEE-EGMSVLFITHDMGVVAEVSDrTIVMFRGD-----VVEtgttddifhrgrHPY-TR----ALLSAVPKLGSM 278
Cdd:PRK13409 251 VARLIRELaEGKYVLVVEHDLAVLDYLAD-NVHIAYGEpgaygVVS------------KPKgVRvginEYLKGYLPEENM 317

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 279 KERLLPARFpiidiktgESQPVADVKDtvsggRTPILSVKDLTTRFdirsGLFgrkSGAVHAVEkvsfdLAEGETLSLVG 358
Cdd:PRK13409 318 RIRPEPIEF--------EERPPRDESE-----RETLVEYPDLTKKL----GDF---SLEVEGGE-----IYEGEVIGIVG 372

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 359 ESGCGKSTTGRSITRLIEPTSGDVMLDgyevLKLdkttlrtmrrSV--QMIFQDPFASL-DPRMSVGTAIMEPFIEHrlg 435
Cdd:PRK13409 373 PNGIGKTTFAKLLAGVLKPDEGEVDPE----LKI----------SYkpQYIKPDYDGTVeDLLRSITDDLGSSYYKS--- 435

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 436 tkqqarekaaDLLEKVGLsPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLN 515
Cdd:PRK13409 436 ----------EIIKPLQL-ERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEERE 504

                        410       420
                 ....*....|....*....|..
gi 549799341 516 LAFLFISHDMAVVERVSHRVAV 537
Cdd:PRK13409 505 ATALVVDHDIYMIDYISDRLMV 526
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
336-535 2.87e-11

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 63.02  E-value: 2.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVL-------KLDKTTLRTMRRSVQMif 408
Cdd:NF040873   3 GGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVayvpqrsEVPDSLPLTVRDLVAM-- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 409 qdpfaSLDPRMSvgtaimePFIEHRlgtkQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVA 488
Cdd:NF040873  81 -----GRWARRG-------LWRRLT----RDDRAAVDDALERVGLA-DLAGRQLGELSGGQRQRALLAQGLAQEADLLLL 143

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 549799341 489 DEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRV 535
Cdd:NF040873 144 DEPTTGLDAESRERI-IALLAEEHARGATVVVVTHDLELVRRADPCV 189
PLN03130 PLN03130
ABC transporter C family member; Provisional
 37-252 3.31e-11

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 66.69  E-value: 3.31e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   37 VVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIegkvMLGGRDLLALPEEEMRKVrgkdISMIFQEPMT- 115
Cdd:PLN03130 1254 VLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRI----LIDGCDISKFGLMDLRKV----LGIIPQAPVLf 1325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  116 ------SLNPifpigkqiaeaLTVHQDisssaakAEVIRLLEKVRIPNA--KNRF------DDYPHQFSGGMRQRVMIAM 181
Cdd:PLN03130 1326 sgtvrfNLDP-----------FNEHND-------ADLWESLERAHLKDVirRNSLgldaevSEAGENFSVGQRQLLSLAR 1387

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341  182 ALASKPKLLIADEPTTALDVTIQGQILdliKTLQEE-EGMSVLFITHDMGVVAEvSDRTIVMFRGDVVETGT 252
Cdd:PLN03130 1388 ALLRRSKILVLDEATAAVDVRTDALIQ---KTIREEfKSCTMLIIAHRLNTIID-CDRILVLDAGRVVEFDT 1455
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
341-552 4.40e-11

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 64.47  E-value: 4.40e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldKTTLRTMRRSVQMIFQdpFASLDPRMS 420
Cdd:PRK13536  57 VNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPV----PARARLARARIGVVPQ--FDNLDLEFT 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 421 VGTAIMEPFIEHRLGTKqQAREKAADLLEKVGLSPDMMRRFPhEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIK 500
Cdd:PRK13536 131 VRENLLVFGRYFGMSTR-EIEAVIPSLLEFARLESKADARVS-DLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHAR 208

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 549799341 501 aQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLG-EIVEIGPRAAV 552
Cdd:PRK13536 209 -HLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGrKIAEGRPHALI 260
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 19-204 5.03e-11

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 63.72  E-value: 5.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSFrVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDkktsrIEGKVMLGGRDLLALPEEEM 98
Cdd:cd03289    3 MTVKDLTAKY-TEGG-NAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-----TEGDIQIDGVSWNSVPLQKW 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  99 RKVRGKDISMIFQEPMTSLNPIFPIGKqiaealtvHQDisssaakAEVIRLLEKVRIpnaKNRFDDYPHQ---------- 168
Cdd:cd03289   76 RKAFGVIPQKVFIFSGTFRKNLDPYGK--------WSD-------EEIWKVAEEVGL---KSVIEQFPGQldfvlvdggc 137

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 549799341 169 -FSGGMRQRVMIAMALASKPKLLIADEPTTALD-VTIQ 204
Cdd:cd03289  138 vLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDpITYQ 175
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 344-501 5.45e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 62.20  E-value: 5.45e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldkttlrtmrrsvqmIFQDPFAS--------- 414
Cdd:PRK13539  21 LSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDI-----------------DDPDVAEAchylghrna 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 415 LDPRMSVGTAIMepFIEHRLGTkqqAREKAADLLEKVGLSPDMMRRFpHEFSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:PRK13539  84 MKPALTVAENLE--FWAAFLGG---EELDIAAALEAVGLAPLAHLPF-GYLSAGQKRRVALARLLVSNRPIWILDEPTAA 157


                 ....*..
gi 549799341 495 LDVSIKA 501
Cdd:PRK13539 158 LDAAAVA 164
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 315-549 5.84e-11

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 62.16  E-value: 5.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRfdirsglfgrkSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRL--IEPTSGDVMLDGYEVLKL 392
Cdd:cd03217    1 LEIKDLHVS-----------VGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHpkYEVTEGEILFKGEDITDL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 393 DkTTLRTmRRSVQMIFQDPfasldPRMSvgtaimepfiehrlGTKqqarekAADLLEKVGLSpdmmrrfpheFSGGQRQR 472
Cdd:cd03217   70 P-PEERA-RLGIFLAFQYP-----PEIP--------------GVK------NADFLRYVNEG----------FSGGEKKR 112

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 473 IAIARSLMLDPKVIVADEAVSALDVSIKAQVCnLLLDLQQNLNLAFLFISHDMAVVERV-SHRVAVMYLGEIVEIGPR 549
Cdd:cd03217  113 NEILQLLLLEPDLAILDEPDSGLDIDALRLVA-EVINKLREEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGDK 189
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 331-547 1.04e-10

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 64.46  E-value: 1.04e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 331 FGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMrrsvqmifqd 410
Cdd:PRK11160 346 FTYPDQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALRQA---------- 415

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 411 pfasldprMSVgtaimepfIEHR-------------LGTKQQAREKAADLLEKVGLSP-------------DMMRrfphE 464
Cdd:PRK11160 416 --------ISV--------VSQRvhlfsatlrdnllLAAPNASDEALIEVLQQVGLEKlleddkglnawlgEGGR----Q 475

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 465 FSGGQRQRIAIARSLMLDPKVIVADEAVSALD-------VSIKAQVCnllldlqqnLNLAFLFISHDMAVVERVShRVAV 537
Cdd:PRK11160 476 LSGGEQRRLGIARALLHDAPLLLLDEPTEGLDaeterqiLELLAEHA---------QNKTVLMITHRLTGLEQFD-RICV 545

                        250
                 ....*....|
gi 549799341 538 MYLGEIVEIG 547
Cdd:PRK11160 546 MDNGQIIEQG 555
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
18-253 1.08e-10

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 62.72  E-value: 1.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  18 VLSVQNLTTSFRVDGGWKSVVRNmsfeIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSRIEGKVMLGGRDL-----LA 92
Cdd:PRK09984   4 IIRVEKLAKTFNQHQALHAVDLN----IHHGEMVALLGPSGSGKS-TLLRHLSGLITGDKSAGSHIELLGRTVqregrLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  93 lpeEEMRKVRGKdISMIFQE-----PMTSLNPIF-------PIGKQIAEALTVHQdisssaaKAEVIRLLEKVRIPNakn 160
Cdd:PRK09984  79 ---RDIRKSRAN-TGYIFQQfnlvnRLSVLENVLigalgstPFWRTCFSWFTREQ-------KQRALQALTRVGMVH--- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 161 rfddYPHQ----FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVS 236
Cdd:PRK09984 145 ----FAHQrvstLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYC 220

                        250
                 ....*....|....*..
gi 549799341 237 DRTIVMFRGDVVETGTT 253
Cdd:PRK09984 221 ERIVALRQGHVFYDGSS 237
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
331-552 1.47e-10

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 62.31  E-value: 1.47e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 331 FGRKSGAvhavEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlklDKTTLRTMRRSVQMIFQD 410
Cdd:PRK10253  17 YGKYTVA----ENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHI---QHYASKEVARRIGLLAQN 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 411 pfASLDPRMSVGTAIMEPFIEHR-LGT--KQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIV 487
Cdd:PRK10253  90 --ATTPGDITVQELVARGRYPHQpLFTrwRKEDEEAVTKAMQATGIT-HLADQSVDTLSGGQRQRAWIAMVLAQETAIML 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 488 ADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG-PRAAV 552
Cdd:PRK10253 167 LDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGaPKEIV 232
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
6-255 1.72e-10

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 63.65  E-value: 1.72e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   6 TSMEQTGGSVS--PVLSVQNLTtsfRVDGGwksVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKV 83
Cdd:PRK09700 251 NAMKENVSNLAheTVFEVRNVT---SRDRK---KVRDISFSVCRGEILGFAGLVGSGRT----ELMNCLFGVDKRAGGEI 320

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  84 MLGGRDLLalPEEEMRKVRgKDISMIFQEPMTslNPIFPiGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNRFD 163
Cdd:PRK09700 321 RLNGKDIS--PRSPLDAVK-KGMAYITESRRD--NGFFP-NFSIAQNMAISRSLKDGGYKGAMGLFHEVDEQRTAENQRE 394

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 164 DYP----------HQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVA 233
Cdd:PRK09700 395 LLAlkchsvnqniTELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLA-DDGKVILMVSSELPEII 473

                        250       260
                 ....*....|....*....|..
gi 549799341 234 EVSDRTIVMFRGDVVETGTTDD 255
Cdd:PRK09700 474 TVCDRIAVFCEGRLTQILTNRD 495
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 35-243 1.89e-10

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 61.13  E-value: 1.89e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  35 KSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLdkktsriegkvmlggrdllalpEEEMRKVRGKDISMIFQEPm 114
Cdd:COG2401   43 RYVLRDLNLEIEPGEIVLIVGASGSGKS----TLLRLL----------------------AGALKGTPVAGCVDVPDNQ- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 115 tslnpiFPIGKQIAEALTVHQDIsssaakAEVIRLLEKVRIPNA---KNRFDDYphqfSGGMRQRVMIAMALASKPKLLI 191
Cdd:COG2401   96 ------FGREASLIDAIGRKGDF------KDAVELLNAVGLSDAvlwLRRFKEL----STGQKFRFRLALLLAERPKLLV 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 549799341 192 ADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVMF 243
Cdd:COG2401  160 IDEFCSHLDRQTAKRVARNLQKLARRAGITLVVATHHYDVIDDLQPDLLIFV 211
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 333-551 2.37e-10

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 63.31  E-value: 2.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  333 RKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRsITRLIEPT---SGDVMLDGYEvlkLDKTTLR-TMRRSVQMIF 408
Cdd:TIGR02633   9 KTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMK-ILSGVYPHgtwDGEIYWSGSP---LKASNIRdTERAGIVIIH 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  409 QDpfASLDPRMSVGTAI-MEPFIEHRLGTKQQAR--EKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKV 485
Cdd:TIGR02633  85 QE--LTLVPELSVAENIfLGNEITLPGGRMAYNAmyLRAKNLLRELQLDADNVTRPVGDYGGGQQQLVEIAKALNKQARL 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341  486 IVADEAVSALDVSiKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEivEIGPRAA 551
Cdd:TIGR02633 163 LILDEPSSSLTEK-ETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQ--HVATKDM 225
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 310-496 2.53e-10

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 63.88  E-value: 2.53e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   310 GRTPILSVKDLTTRFDIrsglFGRKsgavhAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEV 389
Cdd:TIGR01257  924 GLVPGVCVKNLVKIFEP----SGRP-----AVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDI 994

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   390 lkldKTTLRTMRRSVQMIFQDPFasLDPRMSVGTAIMepFIEHRLG-TKQQAREKAADLLEKVGLSPDMMRRfPHEFSGG 468
Cdd:TIGR01257  995 ----ETNLDAVRQSLGMCPQHNI--LFHHLTVAEHIL--FYAQLKGrSWEEAQLEMEAMLEDTGLHHKRNEE-AQDLSGG 1065

                          170       180
                   ....*....|....*....|....*...
gi 549799341   469 QRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:TIGR01257 1066 MQRKLSVAIAFVGDAKVVVLDEPTSGVD 1093
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 135-245 2.71e-10

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 63.26  E-value: 2.71e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 135 QDISSSAAKAEVIRLLEKVRIpnaknrFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTL 214
Cdd:COG1245  428 DDFGSSYYKTEIIKPLGLEKL------LDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRF 501

                         90       100       110
                 ....*....|....*....|....*....|.
gi 549799341 215 QEEEGMSVLFITHDMGVVAEVSDRTIVmFRG 245
Cdd:COG1245  502 AENRGKTAMVVDHDIYLIDYISDRLMV-FEG 531
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 341-503 2.74e-10

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 59.47  E-value: 2.74e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDV-MLDGYEVLkldkttlrtmrrsvqMIFQDPFasldprM 419
Cdd:cd03223   17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIgMPEGEDLL---------------FLPQRPY------L 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 420 SVGTaimepfiehrlgtkqqarekaadLLEKVglspdmmrRFP--HEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:cd03223   76 PLGT-----------------------LREQL--------IYPwdDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDE 124


                 ....*.
gi 549799341 498 SIKAQV 503
Cdd:cd03223  125 ESEDRL 130
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 351-547 2.98e-10

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 63.43  E-value: 2.98e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   351 GETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDkttLRTMRRSVQMIFQDP-FASLDPRMSvgtaiMEPF 429
Cdd:TIGR00957 1312 GEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIG---LHDLRFKITIIPQDPvLFSGSLRMN-----LDPF 1383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   430 IEHRLGTKQQAREkAADLLEKVGLSPDmmrRFPHE-------FSGGQRQRIAIARSLMLDPKVIVADEAVSALDV----- 497
Cdd:TIGR00957 1384 SQYSDEEVWWALE-LAHLKTFVSALPD---KLDHEcaeggenLSVGQRQLVCLARALLRKTKILVLDEATAAVDLetdnl 1459

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 549799341   498 ---SIKAQVcnllldlqqnLNLAFLFISHDMAVVERVShRVAVMYLGEIVEIG 547
Cdd:TIGR00957 1460 iqsTIRTQF----------EDCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFG 1501
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
355-496 3.38e-10

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 62.81  E-value: 3.38e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 355 SLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRtmrRSVQMIFQDPF---ASLDPRMSVGTAIMEpfie 431
Cdd:PRK10790 371 ALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLR---QGVAMVQQDPVvlaDTFLANVTLGRDISE---- 443

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 432 hrlgtkqqarEKAADLLEKVGLSpDMMRRFP-----------HEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:PRK10790 444 ----------EQVWQALETVQLA-ELARSLPdglytplgeqgNNLSVGQKQLLALARVLVQTPQILILDEATANID 508
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 284-541 3.41e-10

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 63.49  E-value: 3.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   284 PARFPIIDiktgESQPVADVKDTV-SGG-RTPILSVKDLTTrfdIRSGlfgrksGAVHAVEKVSFDLAEGETLSLVGESG 361
Cdd:TIGR01257 1909 PAKEPIFD----EDDDVAEERQRIiSGGnKTDILRLNELTK---VYSG------TSSPAVDRLCVGVRPGECFGLLGVNG 1975

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   362 CGKSTTGRSITRLIEPTSGDVMLDGYEVLkldkTTLRTMRRSvqMIFQDPFASLDPRMsvgTAIMEPFIEHRL-GTKQQA 440
Cdd:TIGR01257 1976 AGKTTTFKMLTGDTTVTSGDATVAGKSIL----TNISDVHQN--MGYCPQFDAIDDLL---TGREHLYLYARLrGVPAEE 2046

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   441 REKAADL-LEKVGLSPdMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKaQVCNLLLDLQQNLNLAFL 519
Cdd:TIGR01257 2047 IEKVANWsIQSLGLSL-YADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQAR-RMLWNTIVSIIREGRAVV 2124

                          250       260
                   ....*....|....*....|..
gi 549799341   520 FISHDMAVVERVSHRVAVMYLG 541
Cdd:TIGR01257 2125 LTSHSMEECEALCTRLAIMVKG 2146
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 35-248 4.76e-10

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 59.58  E-value: 4.76e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  35 KSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTS---RIEGKVMLGGrdllaLPEEEMRKVRGKDISMIFQ 111
Cdd:cd03233   20 IPILKDFSGVVKPGEMVLVLGRPGSGCS----TLLKALANRTEgnvSVEGDIHYNG-----IPYKEFAEKYPGEIIYVSE 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 112 EPMtslnpifpigkQIAEaLTVHQDISSSAakaevirllekvripnaKNRFDDYPHQFSGGMRQRVMIAMALASKPKLLI 191
Cdd:cd03233   91 EDV-----------HFPT-LTVRETLDFAL-----------------RCKGNEFVRGISGGERKRVSIAEALVSRASVLC 141

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 192 ADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVA-EVSDRTIVMFRGDVV 248
Cdd:cd03233  142 WDNSTRGLDSSTALEILKCIRTMADVLKTTTFVSLYQASDEIyDLFDKVLVLYEGRQI 199
oligo_HPY TIGR01727
oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model ...
 542-593 5.25e-10

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model represents a domain found in the C-terminal regions of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 213647 [Multi-domain]  Cd Length: 87  Bit Score: 56.22  E-value: 5.25e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 549799341  542 EIVEIGPRAAVFDNPQHPYTKKLMSAVPVP-DPARRQIKrnmATDEIRSPIRP 593
Cdd:TIGR01727   1 KIVETGPAEEIFKNPLHPYTKALLSAIPTIkKRDRKLIS---IPGEVPSLINL 50
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 16-254 6.07e-10

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 60.04  E-value: 6.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  16 SPVLSVQNLTTSfrVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSvtSLSIMRLLDKKTSRIEGKVMLGGRDLLALpE 95
Cdd:CHL00131   5 KPILEIKNLHAS--VNE--NEILKGLNLSINKGEIHAIMGPNGSGKS--TLSKVIAGHPAYKILEGDILFKGESILDL-E 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGkdISMIFQEP------------MTSLNpifpiGKQIAEALTVHQDISSsaakAEVIRllEKVRIPNAKNRF- 162
Cdd:CHL00131  78 PEERAHLG--IFLAFQYPieipgvsnadflRLAYN-----SKRKFQGLPELDPLEF----LEIIN--EKLKLVGMDPSFl 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 163 -DDYPHQFSGGMRQRVMI-AMALaSKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGmSVLFITHDMGVVAEVS-DRT 239
Cdd:CHL00131 145 sRNVNEGFSGGEKKRNEIlQMAL-LDSELAILDETDSGLDIDALKIIAEGINKLMTSEN-SIILITHYQRLLDYIKpDYV 222

                        250
                 ....*....|....*
gi 549799341 240 IVMFRGDVVETGTTD 254
Cdd:CHL00131 223 HVMQNGKIIKTGDAE 237
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 344-528 6.37e-10

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 60.13  E-value: 6.37e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLD-----GY--EVLKLDKTTLRTMRRsvqmifqdpFASLD 416
Cdd:PRK09544  23 VSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNgklriGYvpQKLYLDTTLPLTVNR---------FLRLR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 417 PrmSVGTAIMEPFIEhrlgtkqqaREKAADLLEkvglspdmmrrFP-HEFSGGQRQRIAIARSLMLDPKVIVADEAVSAL 495
Cdd:PRK09544  94 P--GTKKEDILPALK---------RVQAGHLID-----------APmQKLSGGETQRVLLARALLNRPQLLVLDEPTQGV 151

                        170       180       190
                 ....*....|....*....|....*....|...
gi 549799341 496 DVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVV 528
Cdd:PRK09544 152 DVNGQVALYDLIDQLRRELDCAVLMVSHDLHLV 184
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 17-245 6.55e-10

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 58.79  E-value: 6.55e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVtslsimrLLD-----KKTSRIEGKVMLGGRDLl 91
Cdd:cd03232    2 SVLTWKNLNYTVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTT-------LLDvlagrKTAGVITGEILINGRPL- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  92 alpEEEMRKVRGkdismiFQEPMTSLNPifpigkqiaeALTVHQDISSSAAkaevIRLLekvripnaknrfddyphqfSG 171
Cdd:cd03232   74 ---DKNFQRSTG------YVEQQDVHSP----------NLTVREALRFSAL----LRGL-------------------SV 111

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 172 GMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHD-MGVVAEVSDRTIVMFRG 245
Cdd:cd03232  112 EQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKKLA-DSGQAILCTIHQpSASIFEKFDRLLLLKRG 185
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 313-551 7.73e-10

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 61.48  E-value: 7.73e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRsITRLIEPT---SGDVMLDGyEV 389
Cdd:PRK13549   4 YLLEMKNITKTF-----------GGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMK-VLSGVYPHgtyEGEIIFEG-EE 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 390 LKLdKTTLRTMRRSVQMIFQDpfASLDPRMSVGTAIM---EPFIEHRLGTKQQAREkAADLLEKVGLSPDMMRRFpHEFS 466
Cdd:PRK13549  71 LQA-SNIRDTERAGIAIIHQE--LALVKELSVLENIFlgnEITPGGIMDYDAMYLR-AQKLLAQLKLDINPATPV-GNLG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 467 GGQRQRIAIARSLMLDPKVIVADEAVSALDVSiKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEivEI 546
Cdd:PRK13549 146 LGQQQLVEIAKALNKQARLLILDEPTASLTES-ETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGR--HI 222


                 ....*
gi 549799341 547 GPRAA 551
Cdd:PRK13549 223 GTRPA 227
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 342-502 9.62e-10

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 58.66  E-value: 9.62e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 342 EKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyevlkldkTTLRTMRRSVQ--MIFQDPFASLDPRM 419
Cdd:cd03231   17 SGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNG--------GPLDFQRDSIArgLLYLGHAPGIKTTL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 420 SVGTAIMepfIEHRLGtkqqAREKAADLLEKVGLSPDMMRRFpHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSI 499
Cdd:cd03231   89 SVLENLR---FWHADH----SDEQVEEALARVGLNGFEDRPV-AQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAG 160


                 ...
gi 549799341 500 KAQ 502
Cdd:cd03231  161 VAR 163
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 341-496 1.37e-09

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 58.94  E-value: 1.37e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlklDKTTLRTMRRSVQMIFQDPfaSLDPRMS 420
Cdd:COG4604   17 LDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDV---ATTPSRELAKRLAILRQEN--HINSRLT 91

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 421 VGTAIM---EPFIEHRLgtKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:COG4604   92 VRELVAfgrFPYSKGRL--TAEDREIIDEAIAYLDLE-DLADRYLDELSGGQRQRAFIAMVLAQDTDYVLLDEPLNNLD 167
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
136-245 1.49e-09

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 60.98  E-value: 1.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 136 DISSSAAKAEVIRLLEKVRIpnaknrFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQ 215
Cdd:PRK13409 427 DLGSSYYKSEIIKPLQLERL------LDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIA 500

                         90       100       110
                 ....*....|....*....|....*....|
gi 549799341 216 EEEGMSVLFITHDMGVVAEVSDRTIVmFRG 245
Cdd:PRK13409 501 EEREATALVVDHDIYMIDYISDRLMV-FEG 529
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 29-248 1.84e-09

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 60.73  E-value: 1.84e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  29 RVDGGWKS-----VVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGgRDLLA--LPEEEMRKV 101
Cdd:PRK11147   5 SIHGAWLSfsdapLLDNAELHIEDNERVCLVGRNGAGKS----TLMKILNGEVLLDDGRIIYE-QDLIVarLQQDPPRNV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 102 RGKDISMIFQepmtslnpifpiG-KQIAEALTVHQDIS-------SSAAKAEVIRLLEKVRIPNAKnRFDDYPHQ----- 168
Cdd:PRK11147  80 EGTVYDFVAE------------GiEEQAEYLKRYHDIShlvetdpSEKNLNELAKLQEQLDHHNLW-QLENRINEvlaql 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 ----------FSGGMRQRVMIAMALASKPKLLIADEPTTALDV-TIQGqildLIKTLQEEEGmSVLFITHDMGVVAEVSD 237
Cdd:PRK11147 147 gldpdaalssLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDIeTIEW----LEGFLKTFQG-SIIFISHDRSFIRNMAT 221

                        250
                 ....*....|.
gi 549799341 238 RTIVMFRGDVV 248
Cdd:PRK11147 222 RIVDLDRGKLV 232
oligo_HPY pfam08352
Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found ...
 248-291 2.08e-09

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found towards the C-terminus of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid.


Pssm-ID: 400588 [Multi-domain]  Cd Length: 65  Bit Score: 53.94  E-value: 2.08e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 549799341  248 VETGTTDDIFHRGRHPYTRALLSAVPKLGSMKERL--LPARFPIID 291
Cdd:pfam08352   1 VEEGPTDDILENPLHPYTRALLNSVPRLDPPKRPLytIPGNVPSLL 46
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 347-537 2.10e-09

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 58.57  E-value: 2.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 347 DLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkldkttlrtmrrsvqmIFQDPFASLDPRMSVGTAIM 426
Cdd:cd03237   21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTV-----------------SYKPQYIKADYEGTVRDLLS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 427 EpfIEHRLGTKQQARekaADLLEKVGLSPDMMRRFPhEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNL 506
Cdd:cd03237   84 S--ITKDFYTHPYFK---TEIAKPLQIEQILDREVP-ELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKV 157

                        170       180       190
                 ....*....|....*....|....*....|.
gi 549799341 507 LLDLQQNLNLAFLFISHDMAVVERVSHRVAV 537
Cdd:cd03237  158 IRRFAENNEKTAFVVEHDIIMIDYLADRLIV 188
hmuV PRK13547
heme ABC transporter ATP-binding protein;
333-558 2.73e-09

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 58.30  E-value: 2.73e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 333 RKSGAVhaVEKVSFDLAEGETLSLVGESGCGKSTTGRSIT-RLIEPT-------SGDVMLDGYEVLKLDKTTLRTMRRSV 404
Cdd:PRK13547  11 RRHRAI--LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAgDLTGGGaprgarvTGDVTLNGEPLAAIDAPRLARLRAVL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 405 QMIFQDPFA-SLDPRMSVGTAimePFIEHRLGTKQQAREKAADLLEKVGLSPdMMRRFPHEFSGGQRQRIAIARSL---- 479
Cdd:PRK13547  89 PQAAQPAFAfSAREIVLLGRY---PHARRAGALTHRDGEIAWQALALAGATA-LVGRDVTTLSGGELARVQFARVLaqlw 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 480 -----MLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAVFd 554
Cdd:PRK13547 165 pphdaAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADVL- 243


                 ....
gi 549799341 555 NPQH 558
Cdd:PRK13547 244 TPAH 247
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 19-204 2.76e-09

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 60.31  E-value: 2.76e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    19 LSVQNLTTSFRVDGgwKSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKktsriEGKVMLGGRDLLALPEEEM 98
Cdd:TIGR01271 1218 MDVQGLTAKYTEAG--RAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLST-----EGEIQIDGVSWNSVTLQTW 1290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    99 RKVRGkdisMIFQEpmtslnpIFPIGKQIAEALTVHQDISSSaakaEVIRLLEKVRIPNAKNRF--------DDYPHQFS 170
Cdd:TIGR01271 1291 RKAFG----VIPQK-------VFIFSGTFRKNLDPYEQWSDE----EIWKVAEEVGLKSVIEQFpdkldfvlVDGGYVLS 1355

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 549799341   171 GGMRQRVMIAMALASKPKLLIADEPTTALD-VTIQ 204
Cdd:TIGR01271 1356 NGHKQLMCLARSILSKAKILLLDEPSAHLDpVTLQ 1390
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 170-537 3.67e-09

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 59.41  E-value: 3.67e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVtiqGQILDLIKTLQE--EEGMSVLFITHDMGVVAEVSDrTIVMFRGD- 246
Cdd:COG1245  214 SGGELQRVAIAAALLRDADFYFFDEPSSYLDI---YQRLNVARLIRElaEEGKYVLVVEHDLAILDYLAD-YVHILYGEp 289

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 247 ----VVEtgttddifhrgrHPY-TR----ALLSAVPKLGSMKERLLPARFpiidiktgESQPVADVKDtvsggRTPILSV 317
Cdd:COG1245  290 gvygVVS------------KPKsVRvginQYLDGYLPEENVRIRDEPIEF--------EVHAPRREKE-----EETLVEY 344

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 318 KDLTTRFDirsglfGRK----SGAVHavekvsfdlaEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLD-------G 386
Cdd:COG1245  345 PDLTKSYG------GFSleveGGEIR----------EGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDlkisykpQ 408

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 387 YEVLKLDKTtlrtmrrsVQMIFqdpfasldpRMSVGTAIMEPFIEHrlgtkqqarekaaDLLEKVGLSPdMMRRFPHEFS 466
Cdd:COG1245  409 YISPDYDGT--------VEEFL---------RSANTDDFGSSYYKT-------------EIIKPLGLEK-LLDKNVKDLS 457

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341 467 GGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAV 537
Cdd:COG1245  458 GGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHDIYLIDYISDRLMV 528
oligo_HPY TIGR01727
oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model ...
 247-283 4.67e-09

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model represents a domain found in the C-terminal regions of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 213647 [Multi-domain]  Cd Length: 87  Bit Score: 53.52  E-value: 4.67e-09
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 549799341  247 VVETGTTDDIFHRGRHPYTRALLSAVPKLGSMKERLL 283
Cdd:TIGR01727   2 IVETGPAEEIFKNPLHPYTKALLSAIPTIKKRDRKLI 38
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
315-497 7.59e-09

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 55.97  E-value: 7.59e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFDIRSgLFgrksgavhavEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDK 394
Cdd:PRK13538   2 LEARNLACERDERI-LF----------SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRD 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 395 TTLRTMRrsvqmifqdpfasldprmsvgtaimepFIEHRLGTK-----------------QQAREKAADLLEKVGLspdm 457
Cdd:PRK13538  71 EYHQDLL---------------------------YLGHQPGIKteltalenlrfyqrlhgPGDDEALWEALAQVGL---- 119

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 549799341 458 mRRF---P-HEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:PRK13538 120 -AGFedvPvRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDK 162
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 342-537 8.76e-09

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 58.89  E-value: 8.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  342 EKVSFDLAEGETLSLVGESGCGKSTTgrsitrlIEPTSGDVMLDGYEVLKLDkttLRTMRRSVQMIFQDPfasldprMSV 421
Cdd:PTZ00265 1246 EEQNVGMKNVNEFSLTKEGGSGEDST-------VFKNSGKILLDGVDICDYN---LKDLRNLFSIVSQEP-------MLF 1308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  422 GTAIMEPFiehRLGTKQQAREKAADLLeKVGLSPDMMRRFPHEF-----------SGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:PTZ00265 1309 NMSIYENI---KFGKEDATREDVKRAC-KFAAIDEFIESLPNKYdtnvgpygkslSGGQKQRIAIARALLREPKILLLDE 1384

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 549799341  491 AVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERvSHRVAV 537
Cdd:PTZ00265 1385 ATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRIASIKR-SDKIVV 1430
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 308-496 9.22e-09

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 58.77  E-value: 9.22e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   308 SGGRtpiLSVKDLTTRFdirsglfgrKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEpTSGDVMLDGy 387
Cdd:TIGR01271 1214 SGGQ---MDVQGLTAKY---------TEAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDG- 1279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   388 evLKLDKTTLRTMRRSVQMIFQDPFA-SLDPRMSvgtaiMEPFiehrlgtKQQAREKAADLLEKVGLSpDMMRRFPHE-- 464
Cdd:TIGR01271 1280 --VSWNSVTLQTWRKAFGVIPQKVFIfSGTFRKN-----LDPY-------EQWSDEEIWKVAEEVGLK-SVIEQFPDKld 1344

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 549799341   465 ---------FSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:TIGR01271 1345 fvlvdggyvLSNGHKQLMCLARSILSKAKILLLDEPSAHLD 1385
PTZ00243 PTZ00243
ABC transporter; Provisional
 343-557 1.02e-08

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 58.64  E-value: 1.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  343 KVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlklDKTTLRTMRRSVQMIFQDPFAsLDP--RMS 420
Cdd:PTZ00243 1328 GVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREI---GAYGLRELRRQFSMIPQDPVL-FDGtvRQN 1403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  421 VgtaimEPFIEhrlgtKQQAREKAAdlLEKVGLSpdmmRRFPHE--------------FSGGQRQRIAIARSLM-LDPKV 485
Cdd:PTZ00243 1404 V-----DPFLE-----ASSAEVWAA--LELVGLR----ERVASEsegidsrvleggsnYSVGQRQLMCMARALLkKGSGF 1467

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  486 IVADEAVS----ALDVSIKAQVcnllldlqqnlNLAF-----LFISHDMAVVERVShRVAVMYLGEIVEIG-PRAAVFdN 555
Cdd:PTZ00243 1468 ILMDEATAnidpALDRQIQATV-----------MSAFsaytvITIAHRLHTVAQYD-KIIVMDHGAVAEMGsPRELVM-N 1534


                  ..
gi 549799341  556 PQ 557
Cdd:PTZ00243 1535 RQ 1536
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 174-546 1.22e-08

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 57.82  E-value: 1.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 174 RQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEeGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTT 253
Cdd:PRK10982 140 MQMIEIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKER-GCGIVYISHKMEEIFQLCDEITILRDGQWIATQPL 218

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 254 DDifhrgrhpytralLSAVPKLGSMKERLLPARFPIIDIKTGESqpvadvkdtvsggrtpILSVKDLTtrfdirsglfgr 333
Cdd:PRK10982 219 AG-------------LTMDKIIAMMVGRSLTQRFPDKENKPGEV----------------ILEVRNLT------------ 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 334 kSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlkLDKTTLRTMRRSVQMIFQDP-- 411
Cdd:PRK10982 258 -SLRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKI--NNHNANEAINHGFALVTEERrs 334

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 412 ---FASLDPRMSVGTAIMEPFIEhRLGTKQQAREKAadlleKVGLSPDMMR-RFPHE------FSGGQRQRIAIARSLML 481
Cdd:PRK10982 335 tgiYAYLDIGFNSLISNIRNYKN-KVGLLDNSRMKS-----DTQWVIDSMRvKTPGHrtqigsLSGGNQQKVIIGRWLLT 408

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 482 DPKVIVADEAVSALDVSIKAQVcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEI 546
Cdd:PRK10982 409 QPEILMLDEPTRGIDVGAKFEI-YQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNGLVAGI 472
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
344-552 1.26e-08

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 56.33  E-value: 1.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKttlRTMRRSVQMIFQD-PFASldpRMSVG 422
Cdd:PRK10575  30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS---KAFARKVAYLPQQlPAAE---GMTVR 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 423 TAI-MEPFIEH----RLGtkQQAREKAADLLEKVGLSPdMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:PRK10575 104 ELVaIGRYPWHgalgRFG--AADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDI 180

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 498 SIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIGPRAAV 552
Cdd:PRK10575 181 AHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEL 235
PLN03073 PLN03073
ABC transporter F family; Provisional
 325-497 1.27e-08

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 57.95  E-value: 1.27e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 325 DIRSGLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSIT-RLIE--PTSGDVMLDGYEVLKLDKTTL---- 397
Cdd:PLN03073 177 DIHMENFSISVGGRDLIVDASVTLAFGRHYGLVGRNGTGKTTFLRYMAmHAIDgiPKNCQILHVEQEVVGDDTTALqcvl 256

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 398 -------RTMRRSVQMIFQD-----PFASLDPRMSVGTAIMEPFIEHRLGT---------KQQAREKAADLLEKVGLSPD 456
Cdd:PLN03073 257 ntdiertQLLEEEAQLVAQQrelefETETGKGKGANKDGVDKDAVSQRLEEiykrlelidAYTAEARAASILAGLSFTPE 336

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 549799341 457 MMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:PLN03073 337 MQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDL 377
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
336-490 1.28e-08

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 56.04  E-value: 1.28e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 336 GAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLklDKTTLRTMRRSVQMIFQDpfASL 415
Cdd:PRK11614  16 GKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDIT--DWQTAKIMREAVAIVPEG--RRV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 416 DPRMSVGTAI-MEPFIEHRlgtkQQAREKaadlLEKV-GLSPDMMRRFPHE---FSGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:PRK11614  92 FSRMTVEENLaMGGFFAER----DQFQER----IKWVyELFPRLHERRIQRagtMSGGEQQMLAIGRALMSQPRLLLLDE 163
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 47-246 2.88e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 53.15  E-value: 2.88e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    47 PRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIegkVMLGGRDLLALPEEEMRKVrgkdismifqepmtslnpifpigkq 126
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGV---IYIDGEDILEEVLDQLLLI------------------------- 52

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   127 iaealtvhqdisssaakaevirllekvripnaknRFDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQ 206
Cdd:smart00382  53 ----------------------------------IVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEAL 98

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 549799341   207 ILDLIKT-----LQEEEGMSVLFITHDMGVVAE-----VSDRTIVMFRGD 246
Cdd:smart00382  99 LLLLEELrllllLKSEKNLTVILTTNDEKDLGPallrrRFDRRIVLLLIL 148
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 315-496 3.34e-08

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 55.25  E-value: 3.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 315 LSVKDLTTRFdirsglfgrkSGAVHAV-EKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEpTSGDVMLDGyevLKLD 393
Cdd:cd03289    3 MTVKDLTAKY----------TEGGNAVlENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDG---VSWN 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 394 KTTLRTMRRSVQMIFQDPFASLDP-RMSvgtaiMEPFiehrlgtKQQAREKAADLLEKVGLSpDMMRRFPHE-------- 464
Cdd:cd03289   69 SVPLQKWRKAFGVIPQKVFIFSGTfRKN-----LDPY-------GKWSDEEIWKVAEEVGLK-SVIEQFPGQldfvlvdg 135

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 549799341 465 ---FSGGQRQRIAIARSLMLDPKVIVADEAVSALD 496
Cdd:cd03289  136 gcvLSHGHKQLMCLARSVLSKAKILLLDEPSAHLD 170
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 326-499 3.60e-08

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 54.26  E-value: 3.60e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 326 IRSGLFGRKSGaVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRR-SV 404
Cdd:cd03290    3 VTNGYFSWGSG-LATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRySV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 405 QMIFQDPF---ASLDPRMSVGTaimePFiehrlgTKQqaREKAadLLEKVGLSPDMmRRFPH-----------EFSGGQR 470
Cdd:cd03290   82 AYAAQKPWllnATVEENITFGS----PF------NKQ--RYKA--VTDACSLQPDI-DLLPFgdqteigergiNLSGGQR 146

                        170       180
                 ....*....|....*....|....*....
gi 549799341 471 QRIAIARSLMLDPKVIVADEAVSALDVSI 499
Cdd:cd03290  147 QRICVARALYQNTNIVFLDDPFSALDIHL 175
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 313-555 5.97e-08

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 55.67  E-value: 5.97e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 313 PILSVKDLttrfdirsgLFGRKSGAVH-AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLK 391
Cdd:PRK13545  20 PFDKLKDL---------FFRSKDGEYHyALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAALI 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 392 LDKTTLRTMRRSVQMIfqdpfaSLDPRMsvgtaimepfiehrLG-TKQQAREKAADLLEKVGLSpdmmrRFPHE----FS 466
Cdd:PRK13545  91 AISSGLNGQLTGIENI------ELKGLM--------------MGlTKEKIKEIIPEIIEFADIG-----KFIYQpvktYS 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 467 GGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQvCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEI 546
Cdd:PRK13545 146 SGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKK-CLDKMNEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEY 224


                 ....*....
gi 549799341 547 GPRAAVFDN 555
Cdd:PRK13545 225 GDIKEVVDH 233
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 312-547 7.84e-08

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 53.88  E-value: 7.84e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 312 TPILSVKDLTTRFDIRSGLFGrksgavhavekVSFDLAEGETLSLVGESGCGKSTTGRSITRliEP----TSGDVMLDGY 387
Cdd:CHL00131   5 KPILEIKNLHASVNENEILKG-----------LNLSINKGEIHAIMGPNGSGKSTLSKVIAG--HPaykiLEGDILFKGE 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 388 EVLKLDkTTLRTmRRSVQMIFQDPFASldPRMSvgtaiMEPFIEHRLGTKQQAREKA-----------ADLLEKVGLSPD 456
Cdd:CHL00131  72 SILDLE-PEERA-HLGIFLAFQYPIEI--PGVS-----NADFLRLAYNSKRKFQGLPeldplefleiiNEKLKLVGMDPS 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 457 MMRRFPHE-FSGGQRQRIAIARSLMLDPKVIVADEAVSALDvsIKA-QVCNLLLDLQQNLNLAFLFISHDMAVVERVS-H 533
Cdd:CHL00131 143 FLSRNVNEgFSGGEKKRNEILQMALLDSELAILDETDSGLD--IDAlKIIAEGINKLMTSENSIILITHYQRLLDYIKpD 220

                        250
                 ....*....|....
gi 549799341 534 RVAVMYLGEIVEIG 547
Cdd:CHL00131 221 YVHVMQNGKIIKTG 234
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 11-289 9.51e-08

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 55.40  E-value: 9.51e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    11 TGGSVSPVLSVQNLTTSFrvDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTslsiMRLLDKKTSRIEGKVMLGGRDL 90
Cdd:TIGR01257 1930 SGGNKTDILRLNELTKVY--SGTSSPAVDRLCVGVRPGECFGLLGVNGAGKTTT----FKMLTGDTTVTSGDATVAGKSI 2003

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    91 LAlpeeemrkvrgkDISMIFQEpmTSLNPIFpigKQIAEALTVHQDISSSAAKAEV-IRLLEKVRIPNAKN-----RFDD 164
Cdd:TIGR01257 2004 LT------------NISDVHQN--MGYCPQF---DAIDDLLTGREHLYLYARLRGVpAEEIEKVANWSIQSlglslYADR 2066

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   165 YPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFR 244
Cdd:TIGR01257 2067 LAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSII-REGRAVVLTSHSMEECEALCTRLAIMVK 2145

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 549799341   245 GDVVETGTTDDIFHRGRHPYTRALlsavpKLGSMKERLLPARFPI 289
Cdd:TIGR01257 2146 GAFQCLGTIQHLKSKFGDGYIVTM-----KIKSPKDDLLPDLNPV 2185
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 17-227 1.18e-07

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 52.57  E-value: 1.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  17 PVLSVQNLTTsfrVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSIMRLLDKKTSrieGKVMLGGRDL-LALPE 95
Cdd:PRK13539   1 MMLEGEDLAC---VRGG-RVLFSGLSFTLAAGEALVLTGPNGSGKT-TLLRLIAGLLPPAA---GTIKLDGGDIdDPDVA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  96 EEMRKVRGKDismifqepmtSLNPifpigkqiaeALTVHQDISSSAAkaevIRLLEKVRIPNAKNRFD-----DYPHQF- 169
Cdd:PRK13539  73 EACHYLGHRN----------AMKP----------ALTVAENLEFWAA----FLGGEELDIAAALEAVGlaplaHLPFGYl 128

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMsVLFITH 227
Cdd:PRK13539 129 SAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIRAHLAQGGI-VIAATH 185
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 41-259 1.34e-07

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 54.95  E-value: 1.34e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    41 MSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGGrDLLALPEEEMRKVRGKDISMIFQEPmtsLNPi 120
Cdd:TIGR00957  657 ITFSIPEGALVAVVGQVGCGKS----SLLSALLAEMDKVEGHVHMKG-SVAYVPQQAWIQNDSLRENILFGKA---LNE- 727

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   121 fPIGKQIAEALTVHQDIsssaakaEVIRLLEKVRIpnaknrfDDYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALD 200
Cdd:TIGR00957  728 -KYYQQVLEACALLPDL-------EILPSGDRTEI-------GEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVD 792

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   201 VTIQGQILD-LIKTLQEEEGMSVLFITHDMGVVAEVsDRTIVMFRGDVVETGTTDDIFHR 259
Cdd:TIGR00957  793 AHVGKHIFEhVIGPEGVLKNKTRILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQR 851
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 37-232 1.43e-07

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 55.04  E-value: 1.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   37 VVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKVMLGgrDLLALPEEEMRKVRGKdISMIFQEPMT- 115
Cdd:PTZ00265  400 IYKDLNFTLTEGKTYAFVGESGCGKS----TILKLIERLYDPTEGDIIIN--DSHNLKDINLKWWRSK-IGVVSQDPLLf 472

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  116 -------------SLNPIFPIGKQIAEALTVHQDISSSAAK---------------------------------AEVIRL 149
Cdd:PTZ00265  473 snsiknnikyslySLKDLEALSNYYNEDGNDSQENKNKRNScrakcagdlndmsnttdsneliemrknyqtikdSEVVDV 552

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  150 LEKVRIPNAKNRFDDY--------PHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMS 221
Cdd:PTZ00265  553 SKKVLIHDFVSALPDKyetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRI 632

                         250
                  ....*....|.
gi 549799341  222 VLFITHDMGVV 232
Cdd:PTZ00265  633 TIIIAHRLSTI 643
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 143-241 1.92e-07

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 51.42  E-value: 1.92e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 143 KAEVIRLLEKVRIPNAKNRFDD-----YPHQF---SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTL 214
Cdd:cd03222   38 KTTAVKILAGQLIPNGDNDEWDgitpvYKPQYidlSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRL 117

                         90       100
                 ....*....|....*....|....*..
gi 549799341 215 QEEEGMSVLFITHDMGVVAEVSDRTIV 241
Cdd:cd03222  118 SEEGKKTALVVEHDLAVLDYLSDRIHV 144
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 346-535 2.63e-07

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 53.80  E-value: 2.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 346 FDLAEGETLSLVGESGCGKSTtgrsitrLIEPTSGDVMLD-GYEVLKLDKTTLRtmrrsVQmifQDPfasldPRMSVGT- 423
Cdd:PRK11147  24 LHIEDNERVCLVGRNGAGKST-------LMKILNGEVLLDdGRIIYEQDLIVAR-----LQ---QDP-----PRNVEGTv 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 424 ------------AIMEPF--IEHRLGT-------KQQAR--------------EKAADLLEKVGLSPDMMRRfphEFSGG 468
Cdd:PRK11147  84 ydfvaegieeqaEYLKRYhdISHLVETdpseknlNELAKlqeqldhhnlwqleNRINEVLAQLGLDPDAALS---SLSGG 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 469 QRQRIAIARSLMLDPKVIVADEAVSALDVSikaqvcnllldlQQNLNLAFL--------FISHDMAVVERVSHRV 535
Cdd:PRK11147 161 WLRKAALGRALVSNPDVLLLDEPTNHLDIE------------TIEWLEGFLktfqgsiiFISHDRSFIRNMATRI 223
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 344-547 2.69e-07

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 53.70  E-value: 2.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTtgrsitrLIE------PTSGDVMLDGYEVLKLDKTTLRtmrRSVQMIFQDPfaSLdP 417
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTS-------LLNallgflPYQGSLKINGIELRELDPESWR---KHLSWVGQNP--QL-P 435

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 418 RMSVGTAImepfiehRLGTKQQAREKAADLLEKVGLSpDMMRRFPH-----------EFSGGQRQRIAIARSLMLDPKVI 486
Cdd:PRK11174 436 HGTLRDNV-------LLGNPDASDEQLQQALENAWVS-EFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQLL 507

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 549799341 487 VADEAVSALDVSIKAQVcnLLLDLQQNLNLAFLFISHDMAVVERVShRVAVMYLGEIVEIG 547
Cdd:PRK11174 508 LLDEPTASLDAHSEQLV--MQALNAASRRQTTLMVTHQLEDLAQWD-QIWVMQDGQIVQQG 565
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
332-547 2.81e-07

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 52.13  E-value: 2.81e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 332 GRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGyEVlkldkttlrtmrrSVQMIfqdp 411
Cdd:PRK13546  31 KHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNG-EV-------------SVIAI---- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 412 FASLDPRMSvGTAIMEpFIEHRLGTKQQAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEA 491
Cdd:PRK13546  93 SAGLSGQLT-GIENIE-FKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEA 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 492 VSALDVSIkAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMYLGEIVEIG 547
Cdd:PRK13546 171 LSVGDQTF-AQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYG 225
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 326-554 3.34e-07

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 53.80  E-value: 3.34e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   326 IRSGLFGRKSGAVHAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVmldgyevlkldkttlrTMRRSVQ 405
Cdd:TIGR00957  639 VHNATFTWARDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHV----------------HMKGSVA 702

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   406 MIFQDPF---ASLDPRMSVGTAIMEPFIehrlgtkqQAREKAADLLEKVGLSPDMMRRFPHE----FSGGQRQRIAIARS 478
Cdd:TIGR00957  703 YVPQQAWiqnDSLRENILFGKALNEKYY--------QQVLEACALLPDLEILPSGDRTEIGEkgvnLSGGQKQRVSLARA 774

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 549799341   479 LMLDPKVIVADEAVSALDVSIKAQVCNLLL-DLQQNLNLAFLFISHDMAVVERVSHrVAVMYLGEIVEIGPRAAVFD 554
Cdd:TIGR00957  775 VYSNADIYLFDDPLSAVDAHVGKHIFEHVIgPEGVLKNKTRILVTHGISYLPQVDV-IIVMSGGKISEMGSYQELLQ 850
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 341-497 3.44e-07

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 53.21  E-value: 3.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  341 VEKVSFDLAEGETLSLVGESGCGKSTTGRSIT--------RLIEPTSGDVmldgYEVLKLDKTTLRTMRRsvQMIFqdPF 412
Cdd:TIGR00954 468 IESLSFEVPSGNNLLICGPNGCGKSSLFRILGelwpvyggRLTKPAKGKL----FYVPQRPYMTLGTLRD--QIIY--PD 539

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  413 ASLDPRM-SVGTAIMEPFIEHRlgtkqqareKAADLLEKVGlSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEA 491
Cdd:TIGR00954 540 SSEDMKRrGLSDKDLEQILDNV---------QLTHILEREG-GWSAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDEC 609


                  ....*.
gi 549799341  492 VSALDV 497
Cdd:TIGR00954 610 TSAVSV 615
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 136-243 4.03e-07

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 51.60  E-value: 4.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 136 DISSSAAKAEVIRLLEKVripNAKNRFDDYPHQ-------------FSGGMRQRVMIAMALASKPKLLIADEPTTALDVt 202
Cdd:cd03236   97 DLIPKAVKGKVGELLKKK---DERGKLDELVDQlelrhvldrnidqLSGGELQRVAIAAALARDADFYFFDEPSSYLDI- 172

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 549799341 203 iqGQILDLIKTLQE--EEGMSVLFITHDMGVVAEVSDRTIVMF 243
Cdd:cd03236  173 --KQRLNAARLIRElaEDDNYVLVVEHDLAVLDYLSDYIHCLY 213
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 170-254 4.50e-07

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 52.81  E-value: 4.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDV-- 247
Cdd:PRK10982 393 SGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELA-KKDKGIIIISSEMPELLGITDRILVMSNGLVag 471


                 ....*...
gi 549799341 248 -VETGTTD 254
Cdd:PRK10982 472 iVDTKTTT 479
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 344-503 5.19e-07

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 50.24  E-value: 5.19e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKST-----TGRsitRLIEPTSGDVMLDGYevlkldKTTLRTMRRSVQMIFQDPFasLDPR 418
Cdd:cd03213   28 VSGKAKPGELTAIMGPSGAGKSTllnalAGR---RTGLGVSGEVLINGR------PLDKRSFRKIIGYVPQDDI--LHPT 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 419 MSVgtaimepfiehrlgtkQQAREKAADLLekvGLSpdmmrrfphefsGGQRQRIAIARSLMLDPKVIVADEAVSALDVS 498
Cdd:cd03213   97 LTV----------------RETLMFAAKLR---GLS------------GGERKRVSIALELVSNPSLLFLDEPTSGLDSS 145


                 ....*
gi 549799341 499 IKAQV 503
Cdd:cd03213  146 SALQV 150
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
304-547 6.32e-07

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 51.66  E-value: 6.32e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 304 KDTVSGGRTPILSVKDLTTRFdirsglfgrksGAVHAVEKVSFDLAEGETLSLVGESGCGKSTtGRSITRLIEPTSGDVM 383
Cdd:NF000106   3 RKTISNGARNAVEVRGLVKHF-----------GEVKAVDGVDLDVREGTVLGVLGP*GAA**R-GALPAHV*GPDAGRRP 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 384 LDGYEVLKLDKTTLRTM--RRSVQMIFQDPFASLDPRMSVGTAIMEpfiehrlgTKQQAREKAADLLEKVGLSpDMMRRF 461
Cdd:NF000106  71 WRF*TWCANRRALRRTIg*HRPVR*GRRESFSGRENLYMIGR*LDL--------SRKDARARADELLERFSLT-EAAGRA 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 462 PHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHdMAVVERVSHRVAVMYLG 541
Cdd:NF000106 142 AAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQY-MEEAEQLAHELTVIDRG 220


                 ....*.
gi 549799341 542 EIVEIG 547
Cdd:NF000106 221 RVIADG 226
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 36-229 1.02e-06

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 50.02  E-value: 1.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  36 SVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKktsrIEGKVMLGGRDLLALPEEEMRKVRGKDISMIFQEP-- 113
Cdd:cd03290   15 ATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQT----LEGKVHWSNKNESEPSFEATRSRNRYSVAYAAQKPwl 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 114 ---MTSLNPIF--PIGKQIAEALTvhqDISSSAAKAEVIRLLEKVRIpnaknrfDDYPHQFSGGMRQRVMIAMALASKPK 188
Cdd:cd03290   91 lnaTVEENITFgsPFNKQRYKAVT---DACSLQPDIDLLPFGDQTEI-------GERGINLSGGQRQRICVARALYQNTN 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 549799341 189 LLIADEPTTALDVTIQGQILD--LIKTLQEEEgMSVLFITHDM 229
Cdd:cd03290  161 IVFLDDPFSALDIHLSDHLMQegILKFLQDDK-RTLVLVTHKL 202
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 349-539 1.25e-06

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 50.06  E-value: 1.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 349 AEGETLSLVGESGCGKSTTGR--------SITRLIEPTSGDVMLDGYEVLKLDKTTLRTMRRSVQMIFQDPFASLDPRMS 420
Cdd:cd03236   24 REGQVLGLVGPNGIGKSTALKilagklkpNLGKFDDPPDWDEILDEFRGSELQNYFTKLLEGDVKVIVKPQYVDLIPKAV 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 421 VGTAImepfiehRLGTKQQAREKAADLLEKVGLSPdMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVS-- 498
Cdd:cd03236  104 KGKVG-------ELLKKKDERGKLDELVDQLELRH-VLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKqr 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 549799341 499 IKAqvcNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMY 539
Cdd:cd03236  176 LNA---ARLIRELAEDDNYVLVVEHDLAVLDYLSDYIHCLY 213
PLN03130 PLN03130
ABC transporter C family member; Provisional
 17-260 1.35e-06

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 51.66  E-value: 1.35e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   17 PVLSVQNLTTSFRVDGGwKSVVRNMSFEIAPRETVAIVGESGSGKsvTSLsIMRLLDKKTSRIEGKVMLGGRdLLALPEe 96
Cdd:PLN03130  613 PAISIKNGYFSWDSKAE-RPTLSNINLDVPVGSLVAIVGSTGEGK--TSL-ISAMLGELPPRSDASVVIRGT-VAYVPQ- 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   97 emrkvrgkdISMIFQEpmtslnpifpigkqiaealTVHQDISSsAAKAEVIRLLEKVRIPNAKNRFDDYPH--------- 167
Cdd:PLN03130  687 ---------VSWIFNA-------------------TVRDNILF-GSPFDPERYERAIDVTALQHDLDLLPGgdlteiger 737

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  168 --QFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDliKTLQEE-EGMSVLFITHDMGVVAEVsDRTIVMFR 244
Cdd:PLN03130  738 gvNISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQVFD--KCIKDElRGKTRVLVTNQLHFLSQV-DRIILVHE 814

                         250
                  ....*....|....*.
gi 549799341  245 GDVVETGTTDDIFHRG 260
Cdd:PLN03130  815 GMIKEEGTYEELSNNG 830
PLN03073 PLN03073
ABC transporter F family; Provisional
 168-497 1.61e-06

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 51.40  E-value: 1.61e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 168 QFSGGMRQRVMIAMALASKPKLLIADEPTTALDVT----IQGQILDLIKTL------QEEEGMSVLFITHDMGvvaevsd 237
Cdd:PLN03073 344 TFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHavlwLETYLLKWPKTFivvshaREFLNTVVTDILHLHG------- 416

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 238 RTIVMFRGDVvetgttdDIFHRGRHPY-------------TRALLSA-VPKLGSMKER--LLPARFPIIDIKTGESQPVA 301
Cdd:PLN03073 417 QKLVTYKGDY-------DTFERTREEQlknqqkafesnerSRSHMQAfIDKFRYNAKRasLVQSRIKALDRLGHVDAVVN 489

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 302 D--------VKDTVSGGrtPILSVKDLTtrfdirsglFGRKSGAVhAVEKVSFDLAEGETLSLVGESGCGKSTTGRSITR 373
Cdd:PLN03073 490 DpdykfefpTPDDRPGP--PIISFSDAS---------FGYPGGPL-LFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISG 557

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 374 LIEPTSGdvmldgyevlkldkTTLRTMRRSVQMIFQDPFASLDPRMSVGTAIMEPFIehrlGTKQQareKAADLLEKVGL 453
Cdd:PLN03073 558 ELQPSSG--------------TVFRSAKVRMAVFSQHHVDGLDLSSNPLLYMMRCFP----GVPEQ---KLRAHLGSFGV 616

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 549799341 454 SPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:PLN03073 617 TGNLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDL 660
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
340-503 1.69e-06

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 49.88  E-value: 1.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLK-LDKTTLRTMRRSVQMIFQDPFASLDPR 418
Cdd:PRK15056  22 ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQaLQKNLVAYVPQSEEVDWSFPVLVEDVV 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 419 MsVGTAIMEPFIEHrlgTKQQAREKAADLLEKVGLSpDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVS 498
Cdd:PRK15056 102 M-MGRYGHMGWLRR---AKKRDRQIVTAALARVDMV-EFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVK 176


                 ....*
gi 549799341 499 IKAQV 503
Cdd:PRK15056 177 TEARI 181
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
27-254 1.70e-06

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 50.87  E-value: 1.70e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  27 SFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLS-IMRLLDKKtsriEGKVMLGGRDLLALPEEEMRKvrgkD 105
Cdd:PRK10789 320 QFTYPQTDHPALENVNFTLKPGQMLGICGPTGSGKS-TLLSlIQRHFDVS----EGDIRFHDIPLTKLQLDSWRS----R 390

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 106 ISMIFQEPM----TSLNPIfPIGK------QIAEAL---TVHQDIsssaakaevirllekVRIPNAknrfddYPHQ---- 168
Cdd:PRK10789 391 LAVVSQTPFlfsdTVANNI-ALGRpdatqqEIEHVArlaSVHDDI---------------LRLPQG------YDTEvger 448

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 ---FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKtlQEEEGMSVLFITHDMGVVAEvSDRTIVMFRG 245
Cdd:PRK10789 449 gvmLSGGQKQRISIARALLLNAEILILDDALSAVDGRTEHQILHNLR--QWGEGRTVIISAHRLSALTE-ASEILVMQHG 525


                 ....*....
gi 549799341 246 DVVETGTTD 254
Cdd:PRK10789 526 HIAQRGNHD 534
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 29-256 1.71e-06

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 51.04  E-value: 1.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  29 RVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVTSlsimRLLDKKTSRIEGKV-MLGGRDLLAlpeeemrkvrgkdIS 107
Cdd:PRK13545  31 SKDGEYHYALNNISFEVPEGEIVGIIGLNGSGKSTLS----NLIAGVTMPNKGTVdIKGSAALIA-------------IS 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 108 MIFQEPMTSLNPIfpigkqiaEALTVHQDISSSAAKAEVIRLLEKVRIpnakNRFDDYP-HQFSGGMRQRVMIAMALASK 186
Cdd:PRK13545  94 SGLNGQLTGIENI--------ELKGLMMGLTKEKIKEIIPEIIEFADI----GKFIYQPvKTYSSGMKSRLGFAISVHIN 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 187 PKLLIADEPTTALDVTIQGQILDLIKTLQEEeGMSVLFITHDMGVVAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:PRK13545 162 PDILVIDEALSVGDQTFTKKCLDKMNEFKEQ-GKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEV 230
GguA NF040905
sugar ABC transporter ATP-binding protein;
170-248 2.45e-06

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 50.56  E-value: 2.45e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:NF040905 406 SGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELA-AEGKGVIVISSELPELLGMCDRIYVMNEGRIT 483
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 351-498 2.91e-06

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 49.14  E-value: 2.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 351 GETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVLKLdktTLRTMRRSVQMIFQDPFA-------SLDPRmsvgt 423
Cdd:cd03288   47 GQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKL---PLHTLRSRLSIILQDPILfsgsirfNLDPE----- 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 424 aimepfiehrlgtKQQAREKAADLLEKVGLSpDMMRRFP-----------HEFSGGQRQRIAIARSLMLDPKVIVADEAV 492
Cdd:cd03288  119 -------------CKCTDDRLWEALEIAQLK-NMVKSLPggldavvteggENFSVGQRQLFCLARAFVRKSSILIMDEAT 184


                 ....*.
gi 549799341 493 SALDVS 498
Cdd:cd03288  185 ASIDMA 190
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 169-500 4.05e-06

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 49.78  E-value: 4.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 169 FSGGMRQRVMIAMALASKPKLLIADEPTTALDVTiqgQILDLIKTLQEEEGMSVLfITHDMGVVAEVSDRTIVMFRGDVV 248
Cdd:PRK10636 150 FSGGWRMRLNLAQALICRSDLLLLDEPTNHLDLD---AVIWLEKWLKSYQGTLIL-ISHDRDFLDPIVDKIIHIEQQSLF 225

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 249 E-TGT----------------------TDDIFH------RGRHPYTRA--LLSAVPKLGSMkERLLPA------RFpiiD 291
Cdd:PRK10636 226 EyTGNyssfevqratrlaqqqamyesqQERVAHlqsyidRFRAKATKAkqAQSRIKMLERM-ELIAPAhvdnpfHF---S 301

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 292 IKTGESQPvadvkdtvsggrTPILSVKDLTTRFDIRSGLfgrksgavhavEKVSFDLAEGETLSLVGESGCGKSTTGRSI 371
Cdd:PRK10636 302 FRAPESLP------------NPLLKMEKVSAGYGDRIIL-----------DSIKLNLVPGSRIGLLGRNGAGKSTLIKLL 358

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 372 TRLIEPTSGDVMLD-----GY------EVLKLDKTTLRTMRRsvqmifqdpfasLDPRMsvgtaimepfiehrlgTKQQA 440
Cdd:PRK10636 359 AGELAPVSGEIGLAkgiklGYfaqhqlEFLRADESPLQHLAR------------LAPQE----------------LEQKL 410

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 441 RekaaDLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIK 500
Cdd:PRK10636 411 R----DYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMR 466
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 44-245 4.11e-06

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 48.56  E-value: 4.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  44 EIAPRETVAIVGESGSGKSvtslSIMRLLDKKTSRIEGKvmlggrdllalPEEEMRKVRGKDISMIFQEPMTSLNPIFPI 123
Cdd:cd03237   21 SISESEVIGILGPNGIGKT----TFIKMLAGVLKPDEGD-----------IEIELDTVSYKPQYIKADYEGTVRDLLSSI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 124 gkqIAEALTVHQDISSSAAKAEVIRLLEKvRIPNaknrfddyphqFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTI 203
Cdd:cd03237   86 ---TKDFYTHPYFKTEIAKPLQIEQILDR-EVPE-----------LSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQ 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 549799341 204 QGQILDLIKTLQEEEGMSVLFITHDMGVVAEVSDRTIVmFRG 245
Cdd:cd03237  151 RLMASKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIV-FEG 191
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 340-490 8.62e-06

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 48.81  E-value: 8.62e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 340 AVEKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVlklDKTTLRTMRRSVQMIFQD--PFASL-- 415
Cdd:PRK10522 338 SVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPV---TAEQPEDYRKLFSAVFTDfhLFDQLlg 414

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 549799341 416 DPRMSVGTAIMEPFIEhRLGTKQQAREKAADLLEKvglspdmmrrfphEFSGGQRQRIAIARSLMLDPKVIVADE 490
Cdd:PRK10522 415 PEGKPANPALVEKWLE-RLKMAHKLELEDGRISNL-------------KLSKGQKKRLALLLALAEERDILLLDE 475
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 170-251 9.61e-06

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 46.55  E-value: 9.61e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIA--MALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVaEVSDRTIVM----- 242
Cdd:cd03238   89 SGGELQRVKLAseLFSEPPGTLFILDEPSTGLHQQDINQLLEVIKGLI-DLGNTVILIEHNLDVL-SSADWIIDFgpgsg 166

                         90
                 ....*....|
gi 549799341 243 -FRGDVVETG 251
Cdd:cd03238  167 kSGGKVVFSG 176
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 342-538 1.40e-05

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 45.13  E-value: 1.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 342 EKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVmldgyevlkldkttlrtmrrsvqmifqdpfaSLDPRMSV 421
Cdd:cd03221   17 KDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIV-------------------------------TWGSTVKI 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 422 GTaimepfiehrlgtkqqarekaadllekvglspdmmrrFPHeFSGGQRQRIAIARSLMLDPKVIVADE--------AVS 493
Cdd:cd03221   66 GY-------------------------------------FEQ-LSGGEKMRLALAKLLLENPNLLLLDEptnhldleSIE 107

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 549799341 494 ALDVSIKAQvcnllldlqqnlNLAFLFISHDMAVVERVSHRVAVM 538
Cdd:cd03221  108 ALEEALKEY------------PGTVILVSHDRYFLDQVATKIIEL 140
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
131-256 1.62e-05

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 48.20  E-value: 1.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 131 LTVHQ---------DISSSAAKAEVIRLLEkvripnaknRFD--DYPHQFSG----GMRQRVMIAMALASKPKLLIADEP 195
Cdd:NF033858 354 LTVRQnlelharlfHLPAAEIAARVAEMLE---------RFDlaDVADALPDslplGIRQRLSLAVAVIHKPELLILDEP 424

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341 196 TTALDVTIQGQILDLIKTLQEEEGMSVlFI-THDMGvVAEVSDRTIVMFRGDVVETGTTDDI 256
Cdd:NF033858 425 TSGVDPVARDMFWRLLIELSREDGVTI-FIsTHFMN-EAERCDRISLMHAGRVLASDTPAAL 484
PLN03211 PLN03211
ABC transporter G-25; Provisional
 351-498 1.78e-05

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 47.95  E-value: 1.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 351 GETLSLVGESGCGKSTTGRSITRLIEPTS--GDVMLDGyevlklDKTTLRTMRRSvQMIFQDPFasLDPRMSV-GTAIME 427
Cdd:PLN03211  94 GEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANN------RKPTKQILKRT-GFVTQDDI--LYPHLTVrETLVFC 164

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 428 PFIE-HRLGTKQQAREKAADLLEKVGLSP----DMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVS 498
Cdd:PLN03211 165 SLLRlPKSLTKQEKILVAESVISELGLTKcentIIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDAT 240
PLN03211 PLN03211
ABC transporter G-25; Provisional
 8-243 2.02e-05

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 47.57  E-value: 2.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   8 MEQTGGSVSPVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSVtslsimrLLDKKTSRIE-----GK 82
Cdd:PLN03211  54 MKNKGSNIKRILGHKPKISDETRQIQERTILNGVTGMASPGEILAVLGPSGSGKST-------LLNALAGRIQgnnftGT 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  83 VMLGGRDLLALPEEEMRKVRGKDIsmIFQEPMTSLNPIFPIGKQIAEALTvhQDISSSAAKAEVIRL-LEKVRIPNAKNR 161
Cdd:PLN03211 127 ILANNRKPTKQILKRTGFVTQDDI--LYPHLTVRETLVFCSLLRLPKSLT--KQEKILVAESVISELgLTKCENTIIGNS 202

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 162 FddyPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHdmgvvaEVSDRTIV 241
Cdd:PLN03211 203 F---IRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLGSLA-QKGKTIVTSMH------QPSSRVYQ 272


                 ..
gi 549799341 242 MF 243
Cdd:PLN03211 273 MF 274
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 53-228 2.15e-05

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 47.42  E-value: 2.15e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  53 IVGESGSGKSvTSLSIMRLLDKKtsrIEGKVMLG-GRDLLALPEE----EMRKVRG----------------KDISMIFQ 111
Cdd:PRK11819  38 VLGLNGAGKS-TLLRIMAGVDKE---FEGEARPApGIKVGYLPQEpqldPEKTVREnveegvaevkaaldrfNEIYAAYA 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 112 EPMTSLNpifpigkQIAEALTVHQDISSSAAKAEVIRLLEK----VRIPNaknrfDDYP-HQFSGGMRQRVMIAMALASK 186
Cdd:PRK11819 114 EPDADFD-------ALAAEQGELQEIIDAADAWDLDSQLEIamdaLRCPP-----WDAKvTKLSGGERRRVALCRLLLEK 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 549799341 187 PKLLIADEPTTALDVTiqgQILDLIKTLQEEEGmSVLFITHD 228
Cdd:PRK11819 182 PDMLLLDEPTNHLDAE---SVAWLEQFLHDYPG-TVVAVTHD 219
PLN03232 PLN03232
ABC transporter C family member; Provisional
 170-260 2.78e-05

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 47.28  E-value: 2.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILD-LIKtlQEEEGMSVLFITHDMGVVAEVsDRTIVMFRGDVV 248
Cdd:PLN03232  742 SGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFDsCMK--DELKGKTRVLVTNQLHFLPLM-DRIILVSEGMIK 818

                          90
                  ....*....|..
gi 549799341  249 ETGTTDDIFHRG 260
Cdd:PLN03232  819 EEGTFAELSKSG 830
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 18-228 3.36e-05

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 46.85  E-value: 3.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   18 VLSVQNLTTSFrvdgGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLL------DKKTSRIEGKVMLGGRDll 91
Cdd:TIGR03719 322 VIEAENLTKAF----GDKLLIDDLSFKLPPGGIVGVIGPNGAGKS----TLFRMItgqeqpDSGTIEIGETVKLAYVD-- 391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   92 alpeeEMRKvrgkdismifqepmtSLNPifpiGKqiaealTVHQDISSSAakaEVIRLlEKVRIPNAK--NRFD------ 163
Cdd:TIGR03719 392 -----QSRD---------------ALDP----NK------TVWEEISGGL---DIIKL-GKREIPSRAyvGRFNfkgsdq 437

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 549799341  164 -DYPHQFSGGMRQRVMIAMALASKPKLLIADEPTTALDVtiqgqildliKTLQE-EEGM-----SVLFITHD 228
Cdd:TIGR03719 438 qKKVGQLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDV----------ETLRAlEEALlnfagCAVVISHD 499
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 466-497 5.50e-05

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 44.38  E-value: 5.50e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 549799341 466 SGGQRQRIAIARSLMLDPKVIVADEAVSALDV 497
Cdd:cd03250  129 SGGQKQRISLARAVYSDADIYLLDDPLSAVDA 160
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 13-245 1.06e-04

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 45.48  E-value: 1.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    13 GSVSPVLSVQNLTTSFRVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvTSLSImrLLDKKTSRI--EGKVMLGGRDL 90
Cdd:TIGR00956  754 ESGEDIFHWRNLTYEVKIKKEKRVILNNVDGWVKPGTLTALMGASGAGKT-TLLNV--LAERVTTGVitGGDRLVNGRPL 830

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    91 LALPEEEMRKVRGKDISMifqepmtslnpifpigkqiaEALTVHQDISSSAA--------KAE-------VIRLLEkvri 155
Cdd:TIGR00956  831 DSSFQRSIGYVQQQDLHL--------------------PTSTVRESLRFSAYlrqpksvsKSEkmeyveeVIKLLE---- 886

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   156 pnaknrFDDYPHQFSG----GM----RQRVMIAMALASKPKLLI-ADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFIT 226
Cdd:TIGR00956  887 ------MESYADAVVGvpgeGLnveqRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTI 959

                          250       260
                   ....*....|....*....|
gi 549799341   227 HD-MGVVAEVSDRTIVMFRG 245
Cdd:TIGR00956  960 HQpSAILFEEFDRLLLLQKG 979
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 37-227 1.20e-04

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 45.12  E-value: 1.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   37 VVRNMSFEIAPRETVAIVGESGSGKSvtslSIMRLLdkktsrieGKV--MLGGRdlLALPEEemrkvrGKdISMIFQEPM 114
Cdd:TIGR00954 467 LIESLSFEVPSGNNLLICGPNGCGKS----SLFRIL--------GELwpVYGGR--LTKPAK------GK-LFYVPQRPY 525

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  115 TSLNPIfpiGKQIAEALTVHQDISSSAAKAEVIRLLEKVRIPNAKNR---FD---DYPHQFSGGMRQRVMIAMALASKPK 188
Cdd:TIGR00954 526 MTLGTL---RDQIIYPDSSEDMKRRGLSDKDLEQILDNVQLTHILEReggWSavqDWMDVLSGGEKQRIAMARLFYHKPQ 602

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 549799341  189 LLIADEPTTALDVTIQGQILDLIKtlqeEEGMSVLFITH 227
Cdd:TIGR00954 603 FAILDECTSAVSVDVEGYMYRLCR----EFGITLFSVSH 637
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 19-245 1.27e-04

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 43.61  E-value: 1.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  19 LSVQNLTTSF-RVDGGWKSVVRNMSFEIAPRETVAIVGESGSGKSvtSLsIMRLLdKKTSRIEGKVMLGGRdllalpeee 97
Cdd:cd03250    1 ISVEDASFTWdSGEQETSFTLKDINLEVPKGELVAIVGPVGSGKS--SL-LSALL-GELEKLSGSVSVPGS--------- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341  98 mrkvrgkdISMIFQEPM---TSL--NPIFpiGKQIAE----------ALTvhQDISSSAA--KAEV----IRLlekvrip 156
Cdd:cd03250   68 --------IAYVSQEPWiqnGTIreNILF--GKPFDEeryekvikacALE--PDLEILPDgdLTEIgekgINL------- 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 157 naknrfddyphqfSGGMRQRVMIAMALASKPKLLIADEPTTALDV---------TIQGQILDLiKTlqeeegmsVLFITH 227
Cdd:cd03250  129 -------------SGGQKQRISLARAVYSDADIYLLDDPLSAVDAhvgrhifenCILGLLLNN-KT--------RILVTH 186

                        250
                 ....*....|....*...
gi 549799341 228 DMGVVAEVsDRTIVMFRG 245
Cdd:cd03250  187 QLQLLPHA-DQIVVLDNG 203
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 176-228 1.41e-04

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 43.36  E-value: 1.41e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 549799341 176 RVMIAMALASKPKLLIADEPTTALDV-TIQGQILDLIKTLQEEEGMSVLFITHD 228
Cdd:cd03240  129 RLALAETFGSNCGILALDEPTTNLDEeNIEESLAEIIEERKSQKNFQLIVITHD 182
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 167-242 1.47e-04

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 42.73  E-value: 1.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 167 HQFSGGMRQRVMIAMALAS---KPK-LLIADEPTTALDVTIQGQILDLIK-TLQeeEGMSVLFITHDMGvVAEVSDRTIV 241
Cdd:cd03227   76 LQLSGGEKELSALALILALaslKPRpLYILDEIDRGLDPRDGQALAEAILeHLV--KGAQVIVITHLPE-LAELADKLIH 152


                 .
gi 549799341 242 M 242
Cdd:cd03227  153 I 153
ABC_UvrA_II cd03271
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...
 170-252 1.48e-04

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213238 [Multi-domain]  Cd Length: 261  Bit Score: 43.76  E-value: 1.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 170 SGGMRQRVMIAMAL---ASKPKLLIADEPTTAL---DVTiqgQILDLIKTLQeEEGMSVLFITHDMGVVAeVSDRTIVM- 242
Cdd:cd03271  171 SGGEAQRIKLAKELskrSTGKTLYILDEPTTGLhfhDVK---KLLEVLQRLV-DKGNTVVVIEHNLDVIK-CADWIIDLg 245

                         90
                 ....*....|....*
gi 549799341 243 -----FRGDVVETGT 252
Cdd:cd03271  246 peggdGGGQVVASGT 260
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 170-240 1.64e-04

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 44.82  E-value: 1.64e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341  170 SGGMRQRVMIAMALAS---KPKLLIADEPTTALDVTiqgQILDLIKTLQE--EEGMSVLFITHDMGVVaEVSDRTI 240
Cdd:PRK00635  811 SGGEIQRLKLAYELLApskKPTLYVLDEPTTGLHTH---DIKALIYVLQSltHQGHTVVIIEHNMHVV-KVADYVL 882
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 344-389 2.45e-04

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 44.02  E-value: 2.45e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEV 389
Cdd:COG4615  351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPV 396
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 441-542 3.76e-04

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 43.62  E-value: 3.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 441 REKAADLLEKVGLSPdMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVS--IKAqvcNLLLDLQQNLNLAF 518
Cdd:COG1245  190 RGKLDELAEKLGLEN-ILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIYqrLNV---ARLIRELAEEGKYV 265

                         90       100
                 ....*....|....*....|....
gi 549799341 519 LFISHDMAVVERVSHRVAVMYlGE 542
Cdd:COG1245  266 LVVEHDLAILDYLADYVHILY-GE 288
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 344-547 4.44e-04

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 42.47  E-value: 4.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 344 VSFDLAEGETLSLVGESGCGKSTTGRSIT--RLIEPTSGDVMLDGYEVLKLDKTtlRTMRRSVQMIFQDPFASldPRMSv 421
Cdd:PRK09580  20 LNLEVRPGEVHAIMGPNGSGKSTLSATLAgrEDYEVTGGTVEFKGKDLLELSPE--DRAGEGIFMAFQYPVEI--PGVS- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 422 gtaiMEPFIEHRLGTKQQAREKA-------ADLLEK----VGLSPDMMRRFPHE-FSGGQRQRIAIARSLMLDPKVIVAD 489
Cdd:PRK09580  95 ----NQFFLQTALNAVRSYRGQEpldrfdfQDLMEEkialLKMPEDLLTRSVNVgFSGGEKKRNDILQMAVLEPELCILD 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 490 EAVSALDVSiKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVS-HRVAVMYLGEIVEIG 547
Cdd:PRK09580 171 ESDSGLDID-ALKIVADGVNSLRDGKRSFIIVTHYQRILDYIKpDYVHVLYQGRIVKSG 228
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 464-539 8.02e-04

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 40.63  E-value: 8.02e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 549799341 464 EFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQVCNLLLDLQQNLNLAFLFISHDMAVVERVSHRVAVMY 539
Cdd:cd03222   71 DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIHVFE 146
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 342-497 9.90e-04

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 42.19  E-value: 9.90e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 342 EKVSFDLAEGETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDGYEVL-KL--------DKTTLRT-MRRSVQM----- 406
Cdd:PRK15064  18 ENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPNERLgKLrqdqfafeEFTVLDTvIMGHTELwevkq 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 407 ----IFQDPFASLDPRMSVGTAIMEpFIEHRlGTKQQARekAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLD 482
Cdd:PRK15064  98 erdrIYALPEMSEEDGMKVADLEVK-FAEMD-GYTAEAR--AGELLLGVGIPEEQHYGLMSEVAPGWKLRVLLAQALFSN 173

                        170
                 ....*....|....*
gi 549799341 483 PKVIVADEAVSALDV 497
Cdd:PRK15064 174 PDILLLDEPTNNLDI 188
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 170-232 1.03e-03

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 42.31  E-value: 1.03e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341  170 SGGMRQRVMIAMALASK---PKLLIADEPTTAL---DVTiqgQILDLIKTLQeEEGMSVLFITHDMGVV 232
Cdd:TIGR00630 831 SGGEAQRIKLAKELSKRstgRTLYILDEPTTGLhfdDIK---KLLEVLQRLV-DKGNTVVVIEHNLDVI 895
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 351-537 1.11e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.66  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   351 GETLSLVGESGCGKSTTGRSITRLIEPTSGDVMldgyeVLKLDKTTLRTMRRSVQMIFqdpfasldprmsvgtaimepfi 430
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVI-----YIDGEDILEEVLDQLLLIIV---------------------- 54

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   431 ehrlgtkqqarekaadllekvglspdmmRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDVS-----IKAQVCN 505
Cdd:smart00382  55 ----------------------------GGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEqeallLLLEELR 106

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 549799341   506 LLLDLQQNLNLAFLFISH------DMAVVERVSHRVAV 537
Cdd:smart00382 107 LLLLLKSEKNLTVILTTNdekdlgPALLRRRFDRRIVL 144
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
441-542 1.16e-03

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 41.72  E-value: 1.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 441 REKAADLLEKVGLSPDMMRRFpHEFSGGQRQRIAIARSLMLDPKVIVADEAVSALDvsIKAQVCNLLLDLQQNLNLAFLF 520
Cdd:PRK13409 190 RGKLDEVVERLGLENILDRDI-SELSGGELQRVAIAAALLRDADFYFFDEPTSYLD--IRQRLNVARLIRELAEGKYVLV 266

                         90       100
                 ....*....|....*....|..
gi 549799341 521 ISHDMAVVERVSHRVAVMYlGE 542
Cdd:PRK13409 267 VEHDLAVLDYLADNVHIAY-GE 287
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
168-256 1.29e-03

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 40.95  E-value: 1.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 168 QFSGGMRQRVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQeEEGMSVLFITHDMGVVAEVSDRTIVMFRGDV 247
Cdd:PRK13546 143 KYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFK-EQNKTIFFVSHNLGQVRQFCTKIAWIEGGKL 221


                 ....*....
gi 549799341 248 VETGTTDDI 256
Cdd:PRK13546 222 KDYGELDDV 230
PLN03130 PLN03130
ABC transporter C family member; Provisional
 466-503 1.68e-03

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 41.65  E-value: 1.68e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 549799341  466 SGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQV 503
Cdd:PLN03130  742 SGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQV 779
PRK cd02026
Phosphoribulokinase (PRK) is an enzyme involved in the Benson-Calvin cycle in chloroplasts or ...
 354-436 1.77e-03

Phosphoribulokinase (PRK) is an enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. This enzyme catalyzes the phosphorylation of D-ribulose 5-phosphate to form D-ribulose 1, 5-biphosphate, using ATP and NADPH produced by the primary reactions of photosynthesis.


Pssm-ID: 238984 [Multi-domain]  Cd Length: 273  Bit Score: 40.78  E-value: 1.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 354 LSLVGESGCGKSTTGRSITRL-IEPTSGDVMLDGYevLKLDkttlRTMRRSVQMIFQDPFASLDPRMS-------VGTAI 425
Cdd:cd02026    2 IGVAGDSGCGKSTFLRRLTSLfGSDLVTVICLDDY--HSLD----RKGRKETGITALDPRANNFDLMYeqlkalkEGQAI 75

                         90
                 ....*....|.
gi 549799341 426 MEPFIEHRLGT 436
Cdd:cd02026   76 EKPIYNHVTGL 86
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 170-228 3.05e-03

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 40.70  E-value: 3.05e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 549799341 170 SGGMRQRVMIAMALASKPKLLIADEPTTALDVtiqgQILDLIKTLQEEEGMSVLFITHD 228
Cdd:PRK11147 442 SGGERNRLLLARLFLKPSNLLILDEPTNDLDV----ETLELLEELLDSYQGTVLLVSHD 496
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 35-254 3.84e-03

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 40.48  E-value: 3.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341    35 KSVVRNMSFEIAPRETVAIVGESGSGKSVTSLSIMRLLDKKTSRIEGKVMLGGrdllaLPEEEMRKVRGKDISMIFQepm 114
Cdd:TIGR00956   74 FDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTDGFHIGVEGVITYDG-----ITPEEIKKHYRGDVVYNAE--- 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   115 tsLNPIFPIgkqiaeaLTVHQDISSSAA-KAEVIRLLEKVRIPNAKNRFD------------------DYPHQFSGGMRQ 175
Cdd:TIGR00956  146 --TDVHFPH-------LTVGETLDFAARcKTPQNRPDGVSREEYAKHIADvymatyglshtrntkvgnDFVRGVSGGERK 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341   176 RVMIAMALASKPKLLIADEPTTALDVTIQGQILDLIKTLQEEEGMSVLFITHDMGVVA-EVSDRTIVMFRGDVVETGTTD 254
Cdd:TIGR00956  217 RVSIAEASLGGAKIQCWDNATRGLDSATALEFIRALKTSANILDTTPLVAIYQCSQDAyELFDKVIVLYEGYQIYFGPAD 296
PRK07429 PRK07429
phosphoribulokinase; Provisional
 354-436 4.37e-03

phosphoribulokinase; Provisional


Pssm-ID: 180975  Cd Length: 327  Bit Score: 39.61  E-value: 4.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 354 LSLVGESGCGKSTTGRSITRLIEPtsgDVM----LDGYEvlKLDkttlRTMRRsvqmifQDPFASLDPR----------- 418
Cdd:PRK07429  11 LGVAGDSGCGKTTFLRGLADLLGE---ELVtvicTDDYH--SYD----RKQRK------ELGITALDPRannldimyehl 75

                         90       100
                 ....*....|....*....|
gi 549799341 419 --MSVGTAIMEPFIEHRLGT 436
Cdd:PRK07429  76 kaLKTGQPILKPIYNHETGT 95
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 351-497 5.63e-03

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 39.77  E-value: 5.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 351 GETLSLVGESGCGKSTTGRSITRLIEPTSGDVMLDG--------YEVLKLDKTTLRTM------RRSVQMIFQDPFASLD 416
Cdd:PRK10636  27 GQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGnwqlawvnQETPALPQPALEYVidgdreYRQLEAQLHDANERND 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549799341 417 prmsvGTAIMEpfIEHRLGTKQ--QAREKAADLLEKVGLSPDMMRRFPHEFSGGQRQRIAIARSLMLDPKVIVADEAVSA 494
Cdd:PRK10636 107 -----GHAIAT--IHGKLDAIDawTIRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNLAQALICRSDLLLLDEPTNH 179


                 ...
gi 549799341 495 LDV 497
Cdd:PRK10636 180 LDL 182
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 168-237 6.13e-03

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 39.77  E-value: 6.13e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549799341 168 QFSGGMRQRVMIAMALASKPKLLIADEPTTALDvtiqgqiLDLIKTLQEE----EGMSVLfITHDMGVVAEVSD 237
Cdd:PRK10636 430 RFSGGEKARLVLALIVWQRPNLLLLDEPTNHLD-------LDMRQALTEAlidfEGALVV-VSHDRHLLRSTTD 495
PLN03232 PLN03232
ABC transporter C family member; Provisional
 466-503 7.61e-03

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 39.57  E-value: 7.61e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 549799341  466 SGGQRQRIAIARSLMLDPKVIVADEAVSALDVSIKAQV 503
Cdd:PLN03232  742 SGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQV 779
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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