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Conserved domains on  [gi|550713947|ref|WP_022646836|]
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MULTISPECIES: primosomal replication protein N [Enterobacteriaceae]

Protein Classification

primosomal replication protein N( domain architecture ID 10006819)

primosomal replication protein N (PriB) is one of three proteins involved in the PriA-dependent replication restart system which participate in the reconstruction of the replisome by further stabilizing the PriA-DNA complex and stimulating PriA helicase activity.

Gene Ontology:  GO:1990158|GO:0006268
PubMed:  29202195

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PriB COG2965
Primosomal replication protein N [Replication, recombination and repair];
1-101 1.24e-47

Primosomal replication protein N [Replication, recombination and repair];


:

Pssm-ID: 442205  Cd Length: 98  Bit Score: 147.26  E-value: 1.24e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550713947   1 MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIISGhENQAITHSLTVGSAVIVQGFISC 80
Cdd:COG2965    1 MMNRLVLSGTVVERPALRYTPAGIPVLEFVLEHRSEQQEAGLPRQVECEIPAVASG-ELAEKLARLPLGSQVRVTGFLAR 79

                         90       100
                 ....*....|....*....|.
gi 550713947  81 HkaKNGLSKMVLHAEQIDLID 101
Cdd:COG2965   80 K--SRGSRQLVLHIQQIELID 98
 
Name Accession Description Interval E-value
PriB COG2965
Primosomal replication protein N [Replication, recombination and repair];
1-101 1.24e-47

Primosomal replication protein N [Replication, recombination and repair];


Pssm-ID: 442205  Cd Length: 98  Bit Score: 147.26  E-value: 1.24e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550713947   1 MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIISGhENQAITHSLTVGSAVIVQGFISC 80
Cdd:COG2965    1 MMNRLVLSGTVVERPALRYTPAGIPVLEFVLEHRSEQQEAGLPRQVECEIPAVASG-ELAEKLARLPLGSQVRVTGFLAR 79

                         90       100
                 ....*....|....*....|.
gi 550713947  81 HkaKNGLSKMVLHAEQIDLID 101
Cdd:COG2965   80 K--SRGSRQLVLHIQQIELID 98
PriB_gamma TIGR04418
primosomal replication protein PriB; Members of this protein family are primosomal replication ...
 3-100 2.50e-44

primosomal replication protein PriB; Members of this protein family are primosomal replication protein N (PriB), virtually always encoded between rpsF (ribosomal protein S6) and rpsR (ribosomal protein S18). Note that only this short form, as found primarily in the gamma-Proteobacteria, of the single-stranded DNA binding protein family (see model TIGR00621) may partner with PriA and be involved in priming for re-initiation of replication. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 275211  Cd Length: 96  Bit Score: 138.87  E-value: 2.50e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550713947    3 NRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIISGhENQAITHSLTVGSAVIVQGFISCHK 82
Cdd:TIGR04418   1 NRLVLSGTVAETPKLRYTPAGIPHLEFVLEHRSQQEEAGQPRQVECEIQAVASG-ELAEKLARLTVGSRVRVTGFLARKS 79

                          90
                  ....*....|....*...
gi 550713947   83 AKNGLsKMVLHAEQIDLI 100
Cdd:TIGR04418  80 HRNGL-QLVLHAQQIEFI 96
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 3-100 7.53e-16

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 66.88  E-value: 7.53e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550713947    3 NRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIISGHENQAITHSLTVGSAVIVQGFISCHK 82
Cdd:pfam00436   2 NKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDRGEGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQTRK 81

                          90       100
                  ....*....|....*....|..
gi 550713947   83 --AKNGLSKMV--LHAEQIDLI 100
Cdd:pfam00436  82 yeDQEGQKRYVteIVADEVQFL 103
 
Name Accession Description Interval E-value
PriB COG2965
Primosomal replication protein N [Replication, recombination and repair];
1-101 1.24e-47

Primosomal replication protein N [Replication, recombination and repair];


Pssm-ID: 442205  Cd Length: 98  Bit Score: 147.26  E-value: 1.24e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550713947   1 MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIISGhENQAITHSLTVGSAVIVQGFISC 80
Cdd:COG2965    1 MMNRLVLSGTVVERPALRYTPAGIPVLEFVLEHRSEQQEAGLPRQVECEIPAVASG-ELAEKLARLPLGSQVRVTGFLAR 79

                         90       100
                 ....*....|....*....|.
gi 550713947  81 HkaKNGLSKMVLHAEQIDLID 101
Cdd:COG2965   80 K--SRGSRQLVLHIQQIELID 98
PriB_gamma TIGR04418
primosomal replication protein PriB; Members of this protein family are primosomal replication ...
 3-100 2.50e-44

primosomal replication protein PriB; Members of this protein family are primosomal replication protein N (PriB), virtually always encoded between rpsF (ribosomal protein S6) and rpsR (ribosomal protein S18). Note that only this short form, as found primarily in the gamma-Proteobacteria, of the single-stranded DNA binding protein family (see model TIGR00621) may partner with PriA and be involved in priming for re-initiation of replication. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 275211  Cd Length: 96  Bit Score: 138.87  E-value: 2.50e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550713947    3 NRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIISGhENQAITHSLTVGSAVIVQGFISCHK 82
Cdd:TIGR04418   1 NRLVLSGTVAETPKLRYTPAGIPHLEFVLEHRSQQEEAGQPRQVECEIQAVASG-ELAEKLARLTVGSRVRVTGFLARKS 79

                          90
                  ....*....|....*...
gi 550713947   83 AKNGLsKMVLHAEQIDLI 100
Cdd:TIGR04418  80 HRNGL-QLVLHAQQIEFI 96
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 3-100 7.53e-16

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 66.88  E-value: 7.53e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550713947    3 NRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIISGHENQAITHSLTVGSAVIVQGFISCHK 82
Cdd:pfam00436   2 NKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDRGEGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQTRK 81

                          90       100
                  ....*....|....*....|..
gi 550713947   83 --AKNGLSKMV--LHAEQIDLI 100
Cdd:pfam00436  82 yeDQEGQKRYVteIVADEVQFL 103
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
3-101 7.33e-05

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 38.67  E-value: 7.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550713947   3 NRLVLSGTVCRTPLRKVSPSGIPHCQFVL--------EHRSVQEEAGFHRqawcqmpVIISGHENQAITHSLTVGSAVIV 74
Cdd:COG0629    2 NKVTLVGRLGKDPELRYTPSGTAVANFRLavnrrykdQDGEWKDETDWHR-------VVAWGKLAENAAEYLKKGDKVYV 74

                         90       100       110
                 ....*....|....*....|....*....|.
gi 550713947  75 QGFISCHK--AKNGL--SKMVLHAEQIDLID 101
Cdd:COG0629   75 EGRLRTRSweDKDGQkrYTTEVVADEIQFLG 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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