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Conserved domains on  [gi|550714816|ref|WP_022647705|]
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MULTISPECIES: glucans biosynthesis protein MdoC [Enterobacter]

Protein Classification

glucans biosynthesis protein C( domain architecture ID 10012085)

glucans biosynthesis protein C, a member of the acyltransferase family, is necessary for the succinyl substitution of periplasmic glucans

EC:  2.1.-.-
Gene Ontology:  GO:0016748|GO:0016741|GO:1900727

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
opgC PRK03854
glucans biosynthesis protein MdoC;
1-375 0e+00

glucans biosynthesis protein MdoC;


:

Pssm-ID: 235167  Cd Length: 375  Bit Score: 541.92  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816   1 MSTTPVQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSQMPSWWLTLFNDFIHAFRMQVFFVISGYFSYMLFLRYPL 80
Cdd:PRK03854   1 MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLLNDFIHAFRMQVFFVISGYFSYMLFLRYPP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816  81 KRWWKVRVERVGIPMLTAIPLLTLPQFIMLQHVKGKAENWPNLSFYEKYNTLVWELISHLWFLLVLVVLTTVSLLIFSQL 160
Cdd:PRK03854  81 KRWLKVRLERVGIPMLTAIPLLTLPQFIMLQYVKGKAEDWPTLSLYEKYNTLAWELISHLWFLLVLVVLTLLCVAIFKRL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816 161 RQRASAATSTFFANITLGKLSLLFLALGVAYAAVRRTLLIVYPPILSDGLFNFVVMQTLFYIPFFLIGALAFIHPRLKAL 240
Cdd:PRK03854 161 RRNLENSDPRPATFGSLGKLSLIFLLLGLGYAAIRRTIFIVYPPILSSGLFNFIVMQTLFYLPFFLLGALAFIFPALKAL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816 241 FTTPSPWCAVGAALAFAAYLLNQRFGSGDAWMYETESVITMLMGLWMVNVVFALGHRLLNFKSSRVTYFVNASLFIYLVH 320
Cdd:PRK03854 241 FTTPSRGCTLGAALAFVAYLLNQRYGSGDAWMYETESVITMVMGLWMVNVVFSLGHRLLNFPSPRVTYLVNASLFIYLVH 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 550714816 321 HPLTLFFGAYITPHIKSNALGFFTGLVFVVGIAIVLYEIHLRIPLLRFLFSGKPQ 375
Cdd:PRK03854 321 HPLTLFFGALITPHISSNWLGFLLGLVFVFGIAFALYEIHLRIPLLRFLFSGKPP 375
 
Name Accession Description Interval E-value
opgC PRK03854
glucans biosynthesis protein MdoC;
1-375 0e+00

glucans biosynthesis protein MdoC;


Pssm-ID: 235167  Cd Length: 375  Bit Score: 541.92  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816   1 MSTTPVQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSQMPSWWLTLFNDFIHAFRMQVFFVISGYFSYMLFLRYPL 80
Cdd:PRK03854   1 MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLLNDFIHAFRMQVFFVISGYFSYMLFLRYPP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816  81 KRWWKVRVERVGIPMLTAIPLLTLPQFIMLQHVKGKAENWPNLSFYEKYNTLVWELISHLWFLLVLVVLTTVSLLIFSQL 160
Cdd:PRK03854  81 KRWLKVRLERVGIPMLTAIPLLTLPQFIMLQYVKGKAEDWPTLSLYEKYNTLAWELISHLWFLLVLVVLTLLCVAIFKRL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816 161 RQRASAATSTFFANITLGKLSLLFLALGVAYAAVRRTLLIVYPPILSDGLFNFVVMQTLFYIPFFLIGALAFIHPRLKAL 240
Cdd:PRK03854 161 RRNLENSDPRPATFGSLGKLSLIFLLLGLGYAAIRRTIFIVYPPILSSGLFNFIVMQTLFYLPFFLLGALAFIFPALKAL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816 241 FTTPSPWCAVGAALAFAAYLLNQRFGSGDAWMYETESVITMLMGLWMVNVVFALGHRLLNFKSSRVTYFVNASLFIYLVH 320
Cdd:PRK03854 241 FTTPSRGCTLGAALAFVAYLLNQRYGSGDAWMYETESVITMVMGLWMVNVVFSLGHRLLNFPSPRVTYLVNASLFIYLVH 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 550714816 321 HPLTLFFGAYITPHIKSNALGFFTGLVFVVGIAIVLYEIHLRIPLLRFLFSGKPQ 375
Cdd:PRK03854 321 HPLTLFFGALITPHISSNWLGFLLGLVFVFGIAFALYEIHLRIPLLRFLFSGKPP 375
Acyl_transf_3 pfam01757
Acyltransferase family; This family includes a range of acyltransferase enzymes. This domain ...
10-358 2.42e-12

Acyltransferase family; This family includes a range of acyltransferase enzymes. This domain is found in a wide range of acyltransferase enzymes, including, mainly, bacterial proteins which catalyze the transfer of acyl groups, other than amino-acyl, from one compound to another, such as Glucans biosynthesis protein C (OPGC) or protein OatA from Listeria monocytogenes serovar 1/2a and Staphylococcus aureus, an integral membrane protein which is responsible for O-acetylation at the C6-hydroxyl group of N-acetylmuramyl residues, forming the corresponding N,6-O-diacetylmuramic acid of the peptidoglycan, a modification that determines lysozyme resistance. This domain is also present in eukaryotic proteins, namely O-acyltransferase like protein (OACYL) from mouse and RHY1 (Regulator of hypoxia-inducible factor 1) and NRF6 (Nose resistant to fluoxetine protein 6) from Caenorhabditis elegans.


Pssm-ID: 426413 [Multi-domain]  Cd Length: 330  Bit Score: 67.19  E-value: 2.42e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816   10 YFLDSIRAWLMLLGIPFHISLIYSSHTWHVnsqmPSWWLTLFNDFIHAFRMQVFFVISGYF-SYMLFLRYPLKRWWKVRV 88
Cdd:pfam01757   2 AYLDLLRGIAILLVVIGHVLLAFGYGGFGL----PLELALLFLVFLGRFGVPLFFFISGYLlAALRRRRRSLFKFIKKRL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816   89 ERVGIPMLTAIPLLTLPQFIMLQHVKGKAenWPNLSFYEKYNTLVWELISHLWFLLVLVVLttvsllifsqlrqrasAAT 168
Cdd:pfam01757  78 LRLLIPYLLWSLLYALLLLLVAGLSVGGA--LLLLLLLNNGPLFFLGVNGHLWFLSALFVF----------------YLL 139
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816  169 STFFANITLGKLSLLFLALGVAYAAVrrtLLIVYPPILSDGLFNFVVMQTLFYIPFFLIGALAFIHPRLKALFTTPSPWC 248
Cdd:pfam01757 140 LPLLLRLLRKLKKSLLLLLLLLLLLL---FLLYILILLVGVPFTVLVLFIFLYLPFFLLGALLARYRKRIRSKRLKLLII 216
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816  249 AVGAALAFAAYLLNQRFGSGDAWMYETESVITMLMGLWMVNVVFALGHRLLNFKSSR--VTYFVNASLFIYLVHHPLTLF 326
Cdd:pfam01757 217 ILLALALLALILLLLFLFGLDPLALEFYGYPSLLLLLLGILLLLLLALLLANLRSLRrlLSYLGKYSFGIYLIHPPILLL 296
                         330       340       350
                  ....*....|....*....|....*....|....
gi 550714816  327 FGAYITPHI--KSNALGFFTGLVFVVGIAIVLYE 358
Cdd:pfam01757 297 LGKLLGLLGlpLLPILLFLLLLVLTLLVSVLLAR 330
NolL COG3594
Fucose 4-O-acetylase or related acetyltransferase [Carbohydrate transport and metabolism];
3-320 1.03e-05

Fucose 4-O-acetylase or related acetyltransferase [Carbohydrate transport and metabolism];


Pssm-ID: 442813  Cd Length: 270  Bit Score: 46.50  E-value: 1.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816   3 TTPVQREYFLDSIRAWLMLLGIPFHISLIYSSHtwhvnsqmpSWWLTLFNDFIHAFRMQVFFVISGYFSYMlfLRYPLKR 82
Cdd:COG3594    2 TSAKKRDPWIDNAKGILIILVVLGHAIGPLIGD---------GDWLRALYLFIYSFHMPLFFFISGYFSKP--SRNGFKK 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816  83 WWKVRVERVGIPMLTAIPLLTLPQFIMLqhvKGKAENWPNLSFYEKYNTLVWELISHLWFLLVLVVLTTVSLLIFsqlrq 162
Cdd:COG3594   71 FLKKKFKRLLVPYLIFQLIYSLFKFLVE---GGEPLDLSLLLLLLDPNGALWFLPALFVWRLLLPLLRRLRRWPL----- 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816 163 rasaatstffanitlgkLSLLFLALGVAYAAVRRTLlivyppilsdglfnFVVMQTLFYIPFFLIGALaFIHPRLKALFT 242
Cdd:COG3594  143 -----------------LIALAIGLLAGYLPSIGLP--------------LSLDRTLVFLPFFLLGYL-LRKYHLERLRR 190
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714816 243 TPSPWCAVGAALAFAAYLLNQRFGSGDAWMYETESVITMLMGLWMVNVVFALGHRLLNFKSSRVTYFVNASLFIYLVH 320
Cdd:COG3594  191 LRVLLLAVAVFLAAALLGFNRYLLLGSRSYGNWYGPLLRLLVALLGILLVLALLALLPRRRTWLTYLGRNTLYIYLLH 268
 
Name Accession Description Interval E-value
opgC PRK03854
glucans biosynthesis protein MdoC;
1-375 0e+00

glucans biosynthesis protein MdoC;


Pssm-ID: 235167  Cd Length: 375  Bit Score: 541.92  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816   1 MSTTPVQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSQMPSWWLTLFNDFIHAFRMQVFFVISGYFSYMLFLRYPL 80
Cdd:PRK03854   1 MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLLNDFIHAFRMQVFFVISGYFSYMLFLRYPP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816  81 KRWWKVRVERVGIPMLTAIPLLTLPQFIMLQHVKGKAENWPNLSFYEKYNTLVWELISHLWFLLVLVVLTTVSLLIFSQL 160
Cdd:PRK03854  81 KRWLKVRLERVGIPMLTAIPLLTLPQFIMLQYVKGKAEDWPTLSLYEKYNTLAWELISHLWFLLVLVVLTLLCVAIFKRL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816 161 RQRASAATSTFFANITLGKLSLLFLALGVAYAAVRRTLLIVYPPILSDGLFNFVVMQTLFYIPFFLIGALAFIHPRLKAL 240
Cdd:PRK03854 161 RRNLENSDPRPATFGSLGKLSLIFLLLGLGYAAIRRTIFIVYPPILSSGLFNFIVMQTLFYLPFFLLGALAFIFPALKAL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816 241 FTTPSPWCAVGAALAFAAYLLNQRFGSGDAWMYETESVITMLMGLWMVNVVFALGHRLLNFKSSRVTYFVNASLFIYLVH 320
Cdd:PRK03854 241 FTTPSRGCTLGAALAFVAYLLNQRYGSGDAWMYETESVITMVMGLWMVNVVFSLGHRLLNFPSPRVTYLVNASLFIYLVH 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 550714816 321 HPLTLFFGAYITPHIKSNALGFFTGLVFVVGIAIVLYEIHLRIPLLRFLFSGKPQ 375
Cdd:PRK03854 321 HPLTLFFGALITPHISSNWLGFLLGLVFVFGIAFALYEIHLRIPLLRFLFSGKPP 375
Acyl_transf_3 pfam01757
Acyltransferase family; This family includes a range of acyltransferase enzymes. This domain ...
10-358 2.42e-12

Acyltransferase family; This family includes a range of acyltransferase enzymes. This domain is found in a wide range of acyltransferase enzymes, including, mainly, bacterial proteins which catalyze the transfer of acyl groups, other than amino-acyl, from one compound to another, such as Glucans biosynthesis protein C (OPGC) or protein OatA from Listeria monocytogenes serovar 1/2a and Staphylococcus aureus, an integral membrane protein which is responsible for O-acetylation at the C6-hydroxyl group of N-acetylmuramyl residues, forming the corresponding N,6-O-diacetylmuramic acid of the peptidoglycan, a modification that determines lysozyme resistance. This domain is also present in eukaryotic proteins, namely O-acyltransferase like protein (OACYL) from mouse and RHY1 (Regulator of hypoxia-inducible factor 1) and NRF6 (Nose resistant to fluoxetine protein 6) from Caenorhabditis elegans.


Pssm-ID: 426413 [Multi-domain]  Cd Length: 330  Bit Score: 67.19  E-value: 2.42e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816   10 YFLDSIRAWLMLLGIPFHISLIYSSHTWHVnsqmPSWWLTLFNDFIHAFRMQVFFVISGYF-SYMLFLRYPLKRWWKVRV 88
Cdd:pfam01757   2 AYLDLLRGIAILLVVIGHVLLAFGYGGFGL----PLELALLFLVFLGRFGVPLFFFISGYLlAALRRRRRSLFKFIKKRL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816   89 ERVGIPMLTAIPLLTLPQFIMLQHVKGKAenWPNLSFYEKYNTLVWELISHLWFLLVLVVLttvsllifsqlrqrasAAT 168
Cdd:pfam01757  78 LRLLIPYLLWSLLYALLLLLVAGLSVGGA--LLLLLLLNNGPLFFLGVNGHLWFLSALFVF----------------YLL 139
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816  169 STFFANITLGKLSLLFLALGVAYAAVrrtLLIVYPPILSDGLFNFVVMQTLFYIPFFLIGALAFIHPRLKALFTTPSPWC 248
Cdd:pfam01757 140 LPLLLRLLRKLKKSLLLLLLLLLLLL---FLLYILILLVGVPFTVLVLFIFLYLPFFLLGALLARYRKRIRSKRLKLLII 216
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816  249 AVGAALAFAAYLLNQRFGSGDAWMYETESVITMLMGLWMVNVVFALGHRLLNFKSSR--VTYFVNASLFIYLVHHPLTLF 326
Cdd:pfam01757 217 ILLALALLALILLLLFLFGLDPLALEFYGYPSLLLLLLGILLLLLLALLLANLRSLRrlLSYLGKYSFGIYLIHPPILLL 296
                         330       340       350
                  ....*....|....*....|....*....|....
gi 550714816  327 FGAYITPHI--KSNALGFFTGLVFVVGIAIVLYE 358
Cdd:pfam01757 297 LGKLLGLLGlpLLPILLFLLLLVLTLLVSVLLAR 330
NolL COG3594
Fucose 4-O-acetylase or related acetyltransferase [Carbohydrate transport and metabolism];
3-320 1.03e-05

Fucose 4-O-acetylase or related acetyltransferase [Carbohydrate transport and metabolism];


Pssm-ID: 442813  Cd Length: 270  Bit Score: 46.50  E-value: 1.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816   3 TTPVQREYFLDSIRAWLMLLGIPFHISLIYSSHtwhvnsqmpSWWLTLFNDFIHAFRMQVFFVISGYFSYMlfLRYPLKR 82
Cdd:COG3594    2 TSAKKRDPWIDNAKGILIILVVLGHAIGPLIGD---------GDWLRALYLFIYSFHMPLFFFISGYFSKP--SRNGFKK 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816  83 WWKVRVERVGIPMLTAIPLLTLPQFIMLqhvKGKAENWPNLSFYEKYNTLVWELISHLWFLLVLVVLTTVSLLIFsqlrq 162
Cdd:COG3594   71 FLKKKFKRLLVPYLIFQLIYSLFKFLVE---GGEPLDLSLLLLLLDPNGALWFLPALFVWRLLLPLLRRLRRWPL----- 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714816 163 rasaatstffanitlgkLSLLFLALGVAYAAVRRTLlivyppilsdglfnFVVMQTLFYIPFFLIGALaFIHPRLKALFT 242
Cdd:COG3594  143 -----------------LIALAIGLLAGYLPSIGLP--------------LSLDRTLVFLPFFLLGYL-LRKYHLERLRR 190
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 550714816 243 TPSPWCAVGAALAFAAYLLNQRFGSGDAWMYETESVITMLMGLWMVNVVFALGHRLLNFKSSRVTYFVNASLFIYLVH 320
Cdd:COG3594  191 LRVLLLAVAVFLAAALLGFNRYLLLGSRSYGNWYGPLLRLLVALLGILLVLALLALLPRRRTWLTYLGRNTLYIYLLH 268
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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