|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10828 |
PRK10828 |
putative oxidoreductase; Provisional |
1-183 |
4.84e-139 |
|
putative oxidoreductase; Provisional
Pssm-ID: 182761 Cd Length: 183 Bit Score: 384.81 E-value: 4.84e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 1 MDALELLVNRRSASRLADPAPVGEQLENILRAGMRAPDHGTLQPWHFFIIEGEGRDRFSQLLEQGAVAAGQDEKGIDKAR 80
Cdd:PRK10828 1 MDALELLLNRRSASRLAEPAPTGEQLQNILRAGMRAPDHGSLQPWRFFVIEGEGRERFSALLEQGAIAAGSDEKAIEKAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 81 NAPFRAPMIIAVVAKCQADHKVPVWEQEMSAGCAVMAMQMAAVAQGFNGIWRTGPLTGSAAVREGFSCGEHDKIVGFLYL 160
Cdd:PRK10828 81 NAPFRAPLIITVVAKCEENHKVPRWEQEVSAGCAVMAMQMAAVAQGFNGIWRSGAWTESPVVREAFGCREQDKIVGFLYL 160
|
170 180
....*....|....*....|...
gi 550714906 161 GTPQLKASSTISVPDTTPFVSRF 183
Cdd:PRK10828 161 GTPQLKASTTINPPDPTPFVTYF 183
|
|
| YdjA-like |
cd02135 |
nitroreductase family protein similar to Escherichia coli YdjA; A subfamily of the ... |
4-162 |
1.61e-65 |
|
nitroreductase family protein similar to Escherichia coli YdjA; A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.
Pssm-ID: 380312 [Multi-domain] Cd Length: 162 Bit Score: 198.21 E-value: 1.61e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 4 LELLVNRRSASRLADPAPV-GEQLENILRAGMRAPDHGTLQPWHFFIIEGEGRDRFSQLLEQGAVAAG--QDEKGIDKAR 80
Cdd:cd02135 1 LELIKTRRSIRKFKLTGAPpEEQLEELLEAAMWAPNHGKLEPWRFIVVTGEGRERLAELLAAAAAARApgADPEKLEKAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 81 NAPFRAPMIIAVVAKCQADHKVPVWEQEMSAGCAVMAMQMAAVAQGFNGIWRTGPLTGSAAVREGFSCGEHDKIVGFLYL 160
Cdd:cd02135 81 EKALRAPVVIAVVAKPDEDPKVPEWEQYAAVGAAVQNLLLAAHALGLGAVWRTGPVTYDPAVREALGLPEDERIVGFLYL 160
|
..
gi 550714906 161 GT 162
Cdd:cd02135 161 GT 162
|
|
| NfnB |
COG0778 |
Nitroreductase [Energy production and conversion]; Nitroreductase is part of the Pathway ... |
3-163 |
1.30e-37 |
|
Nitroreductase [Energy production and conversion]; Nitroreductase is part of the Pathway/BioSystem: Pyrimidine degradation
Pssm-ID: 440541 [Multi-domain] Cd Length: 163 Bit Score: 127.28 E-value: 1.30e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 3 ALELLVNRRSASRLADPAPVGEQLENILRAGMRAPDHGTLQPWHFFIIEGEG-RDRFSQLLEqgavaagqdekgiDKARN 81
Cdd:COG0778 1 LLELLLTRRSVRKFTDKPVSDEELEELLEAARLAPSAGNLQPWRFVVVRDPElRERLAEALA-------------EANQE 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 82 APFRAPMIIAVVAKCQADHKVPVWEQEMSAGCAVMAMQMAAVAQGFNGIWRTGPltGSAAVREGFSCGEHDKIVGFLYLG 161
Cdd:COG0778 68 WVADAPVLIVVCADPDRSEKVPERYALLDAGIAAQNLLLAARALGLGTCWIGGF--DPEKVRELLGLPEGEEPVALLALG 145
|
..
gi 550714906 162 TP 163
Cdd:COG0778 146 YP 147
|
|
| Nitroreductase |
pfam00881 |
Nitroreductase family; The nitroreductase family comprises a group of FMN- or FAD-dependent ... |
7-161 |
5.26e-21 |
|
Nitroreductase family; The nitroreductase family comprises a group of FMN- or FAD-dependent and NAD(P)H-dependent enzymes able to metabolize nitrosubstituted compounds.
Pssm-ID: 425926 [Multi-domain] Cd Length: 168 Bit Score: 84.75 E-value: 5.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 7 LVNRRSaSRLADPAPVG-EQLENILRAGMRAPDHGTLQPWHFFIIE-GEGRDRFSQLLEQGAVAAGQDEKGIDKARN--- 81
Cdd:pfam00881 1 IRQRRS-VRKFDPEPVPkEVLEEILEAARRAPSAGNLQPWRFYVVTdGELRYRLAEAALELLLVEPAAALLLLLRRDanl 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 82 ------APFRAPMIIAVVAKCQAD----HKVPVWEQEMSAGCAVMAMQMAAVAQGFNGIWRTGPLTgsAAVREGFSCGEH 151
Cdd:pfam00881 80 klllqdFLRGAPVLIVITASLSTYlrkaAERAYREALLDAGAAAQNLLLAATSLGLGSCPIGGFDA--AAVRELLGLPDD 157
|
170
....*....|
gi 550714906 152 DKIVGFLYLG 161
Cdd:pfam00881 158 ERLVGLIAVG 167
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10828 |
PRK10828 |
putative oxidoreductase; Provisional |
1-183 |
4.84e-139 |
|
putative oxidoreductase; Provisional
Pssm-ID: 182761 Cd Length: 183 Bit Score: 384.81 E-value: 4.84e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 1 MDALELLVNRRSASRLADPAPVGEQLENILRAGMRAPDHGTLQPWHFFIIEGEGRDRFSQLLEQGAVAAGQDEKGIDKAR 80
Cdd:PRK10828 1 MDALELLLNRRSASRLAEPAPTGEQLQNILRAGMRAPDHGSLQPWRFFVIEGEGRERFSALLEQGAIAAGSDEKAIEKAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 81 NAPFRAPMIIAVVAKCQADHKVPVWEQEMSAGCAVMAMQMAAVAQGFNGIWRTGPLTGSAAVREGFSCGEHDKIVGFLYL 160
Cdd:PRK10828 81 NAPFRAPLIITVVAKCEENHKVPRWEQEVSAGCAVMAMQMAAVAQGFNGIWRSGAWTESPVVREAFGCREQDKIVGFLYL 160
|
170 180
....*....|....*....|...
gi 550714906 161 GTPQLKASSTISVPDTTPFVSRF 183
Cdd:PRK10828 161 GTPQLKASTTINPPDPTPFVTYF 183
|
|
| YdjA-like |
cd02135 |
nitroreductase family protein similar to Escherichia coli YdjA; A subfamily of the ... |
4-162 |
1.61e-65 |
|
nitroreductase family protein similar to Escherichia coli YdjA; A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.
Pssm-ID: 380312 [Multi-domain] Cd Length: 162 Bit Score: 198.21 E-value: 1.61e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 4 LELLVNRRSASRLADPAPV-GEQLENILRAGMRAPDHGTLQPWHFFIIEGEGRDRFSQLLEQGAVAAG--QDEKGIDKAR 80
Cdd:cd02135 1 LELIKTRRSIRKFKLTGAPpEEQLEELLEAAMWAPNHGKLEPWRFIVVTGEGRERLAELLAAAAAARApgADPEKLEKAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 81 NAPFRAPMIIAVVAKCQADHKVPVWEQEMSAGCAVMAMQMAAVAQGFNGIWRTGPLTGSAAVREGFSCGEHDKIVGFLYL 160
Cdd:cd02135 81 EKALRAPVVIAVVAKPDEDPKVPEWEQYAAVGAAVQNLLLAAHALGLGAVWRTGPVTYDPAVREALGLPEDERIVGFLYL 160
|
..
gi 550714906 161 GT 162
Cdd:cd02135 161 GT 162
|
|
| NfnB |
COG0778 |
Nitroreductase [Energy production and conversion]; Nitroreductase is part of the Pathway ... |
3-163 |
1.30e-37 |
|
Nitroreductase [Energy production and conversion]; Nitroreductase is part of the Pathway/BioSystem: Pyrimidine degradation
Pssm-ID: 440541 [Multi-domain] Cd Length: 163 Bit Score: 127.28 E-value: 1.30e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 3 ALELLVNRRSASRLADPAPVGEQLENILRAGMRAPDHGTLQPWHFFIIEGEG-RDRFSQLLEqgavaagqdekgiDKARN 81
Cdd:COG0778 1 LLELLLTRRSVRKFTDKPVSDEELEELLEAARLAPSAGNLQPWRFVVVRDPElRERLAEALA-------------EANQE 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 82 APFRAPMIIAVVAKCQADHKVPVWEQEMSAGCAVMAMQMAAVAQGFNGIWRTGPltGSAAVREGFSCGEHDKIVGFLYLG 161
Cdd:COG0778 68 WVADAPVLIVVCADPDRSEKVPERYALLDAGIAAQNLLLAARALGLGTCWIGGF--DPEKVRELLGLPEGEEPVALLALG 145
|
..
gi 550714906 162 TP 163
Cdd:COG0778 146 YP 147
|
|
| Nitro_FMN_reductase |
cd02062 |
nitroreductase family protein; Proteins of this family catalyze the reduction of flavin or ... |
9-161 |
1.64e-21 |
|
nitroreductase family protein; Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are described as NAD(P)H:FMN oxidoreductases, oxygen-insensitive nitroreductase, flavin reductase P, dihydropteridine reductase, NADH oxidase or NADH dehydrogenase.
Pssm-ID: 380311 [Multi-domain] Cd Length: 139 Bit Score: 85.04 E-value: 1.64e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 9 NRRSASRLADPAPVGEQLENILRAGMRAPDHGTLQPWHFFIIEGEGRDRFSqlleqgavaagqdEKGIDKARNAPFRAPM 88
Cdd:cd02062 3 TRRSIRKFTDKPVPEEKLRKILEAARLAPSAGNLQPWRFIVVRDREKKEKL-------------AKLAAPNQKFIAGAPV 69
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550714906 89 IIAVVakcqADHKVPVWEQEMSAGCAVMAMQMAAVAQGFNGIWRTGPLTGSAAVREGFSCGEHDKIVGFLYLG 161
Cdd:cd02062 70 VIVVV----ADPDKSRPWALEDAGAAAQNLLLAAAALGLGSCWIGGFDFREDKVRELLGIPENLRPVALIAIG 138
|
|
| Nitroreductase |
pfam00881 |
Nitroreductase family; The nitroreductase family comprises a group of FMN- or FAD-dependent ... |
7-161 |
5.26e-21 |
|
Nitroreductase family; The nitroreductase family comprises a group of FMN- or FAD-dependent and NAD(P)H-dependent enzymes able to metabolize nitrosubstituted compounds.
Pssm-ID: 425926 [Multi-domain] Cd Length: 168 Bit Score: 84.75 E-value: 5.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 7 LVNRRSaSRLADPAPVG-EQLENILRAGMRAPDHGTLQPWHFFIIE-GEGRDRFSQLLEQGAVAAGQDEKGIDKARN--- 81
Cdd:pfam00881 1 IRQRRS-VRKFDPEPVPkEVLEEILEAARRAPSAGNLQPWRFYVVTdGELRYRLAEAALELLLVEPAAALLLLLRRDanl 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 82 ------APFRAPMIIAVVAKCQAD----HKVPVWEQEMSAGCAVMAMQMAAVAQGFNGIWRTGPLTgsAAVREGFSCGEH 151
Cdd:pfam00881 80 klllqdFLRGAPVLIVITASLSTYlrkaAERAYREALLDAGAAAQNLLLAATSLGLGSCPIGGFDA--AAVRELLGLPDD 157
|
170
....*....|
gi 550714906 152 DKIVGFLYLG 161
Cdd:pfam00881 158 ERLVGLIAVG 167
|
|
| nitroreductase |
cd02150 |
nitroreductase family protein; A subfamily of the nitroreductase family containing ... |
9-163 |
5.66e-13 |
|
nitroreductase family protein; A subfamily of the nitroreductase family containing uncharacterized proteins. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.often found to be homodimers.
Pssm-ID: 380325 [Multi-domain] Cd Length: 156 Bit Score: 63.39 E-value: 5.66e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 9 NRRSASRLADpAPVG-EQLENILRAGMRAPDHGTLQPWHFFIIegegrdrfsqlleqgavaagQDEKGIDKARNA-PFR- 85
Cdd:cd02150 3 TRRSIRKYTD-KPVEeEDIEKLLRAAMAAPSAGNQQPWHFIVV--------------------TDREKLDKIAEAhPYGk 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 86 ----APMIIAVVAKCQADHKVPVWEQEMSAgcAVMAMQMAAVAQGFNGIWrTG--PLTG-SAAVREGFSCGEHDKIVGFL 158
Cdd:cd02150 62 mlkeAPLAIVVCGDPSKEKAPGYWVQDCSA--ATENILLAAHALGLGAVW-LGvyPFEErVKAIREILNIPENIIPFCVI 138
|
....*
gi 550714906 159 YLGTP 163
Cdd:cd02150 139 ALGYP 143
|
|
| nitroreductase |
cd20610 |
nitroreductase family protein; Proteins of this family catalyze the reduction of flavin or ... |
9-144 |
2.66e-12 |
|
nitroreductase family protein; Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are described as NAD(P)H:FMN oxidoreductases, oxygen-insensitive nitroreductase, flavin reductase P, dihydropteridine reductase, NADH oxidase or NADH dehydrogenase.
Pssm-ID: 380331 [Multi-domain] Cd Length: 167 Bit Score: 61.53 E-value: 2.66e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 9 NRRSASR-LADPAPVgEQLENILRAGMRAPDHGTLQPWHFFIIEGEGRDR------------FSQLLEQgavaagQDEKG 75
Cdd:cd20610 3 KRRSIRKfKPDPVPK-EDIEKILEAANWAPSGMNRQNWEFVVVKGGEKIEkigisikkkneeIARLLEK------VFAEK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 76 IDKARNapFR--------APMIIAVVAKcqaDHKVPVwEQEM---SAGCAVMAMQMAAVAQGFNGIWRTGPLTGSAAVRE 144
Cdd:cd20610 76 PIRFRK--FRrfftlfggAPVLVVVYTE---PYKPPE-ERKPdlqSVSAAIQNLLLAAHALGLGTCWMTGPLYAEDEIEE 149
|
|
| PnbA_NfnB-like |
cd02136 |
nitroreductase similar to Mycobacterium smegmatis NfnB; Members of this family utilize FMN as ... |
6-163 |
1.22e-11 |
|
nitroreductase similar to Mycobacterium smegmatis NfnB; Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source of reducing equivalents in an obligatory two-election transfer mechanism. The enzyme is typically a homodimer. Mycobacterium smegmatis nitroreductase NfnB plays a role in resistance to benzothiazinone.
Pssm-ID: 380313 [Multi-domain] Cd Length: 152 Bit Score: 59.52 E-value: 1.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 6 LLVNRRSAsRLADPAPVG-EQLENILRAGMRAPDHGTLQPWHFFIIEGEGRDRFSQLLeqgavaagqdekgidkarnapF 84
Cdd:cd02136 1 AIKSRRSV-RAFKDKPVPkETIEKILEAARRAPSGKNTQPWRVYVVTGKARERLKKAF---------------------F 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 85 RAPMIIAVVAkcqadHKVPVWEQEMSAGCAVMAMQMAAVAQGFNGIWRtGPLTGSAA-VREGFSCGEHDKIVGFLYLGTP 163
Cdd:cd02136 59 GAPVALFLTM-----DKVLGPWSWFDLGAFLQNLMLAAHALGLGTCPQ-GALAGYPDvVRKELGIPDDEELVCGIALGYP 132
|
|
| nitroreductase |
cd20609 |
nitroreductase family protein; A subfamily of the nitroreductase family containing ... |
4-161 |
8.71e-09 |
|
nitroreductase family protein; A subfamily of the nitroreductase family containing uncharacterized proteins. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.often found to be homodimers.
Pssm-ID: 380330 [Multi-domain] Cd Length: 145 Bit Score: 51.62 E-value: 8.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 4 LELLVNRRSAsRLADPAPVG-EQLENILRAGMRAPDHGTLQPWHFFIIegegrdrfsqlleqgavaagQDEKGIDKARNA 82
Cdd:cd20609 3 LELAKKRYSV-RKFSDKPVEkEKLDKILEAGRLAPTAVNYQPQRILVV--------------------RSEEALEKLAKA 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 83 P---FRAPMIIAVvakCqADHKVpVWEQ--------EMSAGCAVMAMQMAAVAQGFNGIWRTG--PltgsAAVREGFSCG 149
Cdd:cd20609 62 TprfFGAPLVIVV---C-YDKDE-SWKRpydgkdsgDIDAAIVATHMMLAATELGLGTCWVGNfdP----EKVREAFNLP 132
|
170
....*....|..
gi 550714906 150 EHDKIVGFLYLG 161
Cdd:cd20609 133 ENLEPVAILPLG 144
|
|
| nitroreductase |
cd02151 |
nitroreductase family protein; A subfamily of the nitroreductase family containing ... |
5-163 |
1.65e-08 |
|
nitroreductase family protein; A subfamily of the nitroreductase family containing uncharacterized proteins. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.often found to be homodimers..
Pssm-ID: 380326 [Multi-domain] Cd Length: 157 Bit Score: 51.38 E-value: 1.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 5 ELLVNRRSASRLADpAPVG-EQLENILRAGMRAPDHGTLQPWHFFIIegegRDRfsQLLEQGAvaagqdekGIDKARNAP 83
Cdd:cd02151 1 ELLKKRRSIRKYTD-EPIEeEKLEEILEAALLAPSSRNSRPVEFIVV----DDK--ETLKKLS--------ECKPHGSAF 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 84 FR-APMIIAVVAKcqaDHKVPVWEQEMSAGCAvmAMQMAAVAQGFNGIW-----RTGPLTGSA--AVREGFSCGEHDKIV 155
Cdd:cd02151 66 LKgAPAAIVVLAD---TEKSDTWIEDASIAAT--YIQLAAESLGLGSCWiqirnRETQDGKTAeeYVRELLGIPENYRVL 140
|
....*...
gi 550714906 156 GFLYLGTP 163
Cdd:cd02151 141 CIIALGYP 148
|
|
| MhqN-like |
cd02137 |
nitroreductase family protein similar to the NAD(P)H nitroreductase MhqN; A diverse subfamily ... |
4-146 |
5.25e-08 |
|
nitroreductase family protein similar to the NAD(P)H nitroreductase MhqN; A diverse subfamily of the nitroreductase family containing uncharacterized proteins; includes nitroreductases MhqN, YodC, YdgI, DrgA. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.
Pssm-ID: 380314 [Multi-domain] Cd Length: 147 Bit Score: 49.55 E-value: 5.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 4 LELLVNRRSASRLADPAPVG-EQLENILRAGMRAPDHGTLQPWHFFIIEGEgrdrfsQLLEQGAVAAGQDEKGIDkarna 82
Cdd:cd02137 1 LEVIKSRRSVRNFDPDHKIPkEELKEILELATLAPSSFNLQPWRFVVVRDP------ELKAKLAEAAYNQPQVTT----- 69
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550714906 83 pfrAPMIIAVVAkcqadhkvpvweqEMSAGCAVMAMQMAAVAQGfngiWRTGPLTG--SAAVREGF 146
Cdd:cd02137 70 ---ASAVILVLG-------------DLNAGLAAMNLMLAAKAKG----YDTCPMGGfdKEKVAELL 115
|
|
| nitroreductase |
cd02139 |
nitroreductase family protein; A subfamily of the nitroreductase family containing ... |
4-94 |
2.31e-06 |
|
nitroreductase family protein; A subfamily of the nitroreductase family containing uncharacterized proteins. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.
Pssm-ID: 380316 [Multi-domain] Cd Length: 165 Bit Score: 45.54 E-value: 2.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 4 LELLVNRRSAsRLADPAPVG-EQLENILRAGMRAPDHGTLQPWHFFIIEGEgrdrfsQLLEQGAVAAgqdekgidKARNA 82
Cdd:cd02139 2 YEAIKKRRSI-RKYKPTPVEeEKLLRILEAARLAPSAKNRQPWRFIVVKDK------ELKEKLAEAA--------NGQKF 66
|
90
....*....|..
gi 550714906 83 PFRAPMIIAVVA 94
Cdd:cd02139 67 IAEAPVVIVACA 78
|
|
| nitroreductase |
cd20608 |
nitroreductase family protein; Proteins of this family catalyze the reduction of flavin or ... |
4-161 |
3.11e-06 |
|
nitroreductase family protein; Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are described as NAD(P)H:FMN oxidoreductases, oxygen-insensitive nitroreductase, flavin reductase P, dihydropteridine reductase, NADH oxidase or NADH dehydrogenase.
Pssm-ID: 380329 [Multi-domain] Cd Length: 145 Bit Score: 44.63 E-value: 3.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 4 LELLVNRRSASRLADPAPVGEQLENILRAGMRAPDHGTLQPWHFFIIEGEgrdrfsQLLEQGAVAAGQDekgidkaRNAP 83
Cdd:cd20608 1 FEAIKTRRSVRRFSDKPVEEEKLEKILEAARLAPSWANKQCWRFIVVTDK------ETLSELAKKESPS-------NGWL 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 84 FRAPMIIAVVAKCQADhkvpvWEQE------MSAGCAVMAMQMAAVAQGFNGIWRTgpLTGSAAVREGFSCGEHDKIVGF 157
Cdd:cd20608 68 KDAPVIIVVCADPKDS-----GWLNgqnyylVDAAIAMQNLMLAATDLGLGTCWIG--AFDEKKVKEILGIPENIRVVAL 140
|
....
gi 550714906 158 LYLG 161
Cdd:cd20608 141 TPLG 144
|
|
| TdsD-like |
cd02138 |
nitroreductase similar to Burkholderia pseudomallei TdsD; A subfamily of the nitroreductase ... |
6-126 |
8.70e-06 |
|
nitroreductase similar to Burkholderia pseudomallei TdsD; A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to Burkholderia pseudomallei TdsD, may be involved in the processing of organosulfur compounds. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.
Pssm-ID: 380315 [Multi-domain] Cd Length: 174 Bit Score: 44.07 E-value: 8.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 6 LLVNRRSaSRLADPAPVG-EQLENILRAGMRAPDHGTLQPWHFFII--EGEGRDRFSQLLeqgaVAAGQDEkgidkARNA 82
Cdd:cd02138 1 LIAERWS-PRAFSPEPISeEDLLSLFEAARWAPSCFNEQPWRFVVArrDTEAFEKLLDLL----AEGNQSW-----AKNA 70
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 550714906 83 PfrapMIIAVVAKCQADHKV-PVWEQEMSAGCAVMAMQMAAVAQG 126
Cdd:cd02138 71 P----VLIVVLAKTEFDHNGkPNRYALFDTGAAVANLALQATALG 111
|
|
| BluB |
cd02145 |
5,6-dimethylbenzimidazole synthase; BluB catalyzes the O2-dependent conversion of FMNH2 to 5, ... |
5-164 |
2.69e-04 |
|
5,6-dimethylbenzimidazole synthase; BluB catalyzes the O2-dependent conversion of FMNH2 to 5,6-dimethylbenzimidazole (DMB), a component of vitamin B12; is is a subfamily of the nitroreductase family; nitroreductases typically reduce their substrates by using NAD(P)H as electron donor and often use FMN as a cofactor.
Pssm-ID: 380321 Cd Length: 196 Bit Score: 40.03 E-value: 2.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 5 ELLVNRRSASRLADPaPVGEQ-LENILRAGMRAPDHGTLQPWHFFIIegEGRDRFSQLLEQGAVAAGQDEKGIDKARNAP 83
Cdd:cd02145 2 RVIRWRRDVRHFRPD-PVPEEvLERLLQAAHLAPSVGLMQPWRFVRV--RSAATRKAVHELFQRANAEAAEMYTGERAAQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550714906 84 FR---------APMIIAVVAKCQADHKVPVWEQEM------SAGCAVMAMQMAAVAQGFNGIWRTgpLTGSAAVREGFSC 148
Cdd:cd02145 79 YRtlklegieeAPLQLAVFCDRARAGGHGLGRTTMpemdlySSVCAVQNLWLAARAEGLGVGWVS--ILDPDEVKRLLGI 156
|
170
....*....|....*.
gi 550714906 149 GEHDKIVGFLYLGTPQ 164
Cdd:cd02145 157 PEHWEPVAYLCIGYPE 172
|
|
| |
