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Conserved domains on  [gi|550756961|ref|WP_022649051|]
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MULTISPECIES: protein lysine acetyltransferase [Enterobacter]

Protein Classification

bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase( domain architecture ID 11437151)

bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase containing an N-terminal domain similar to ADP-forming acetate--CoA ligase that catalyzes the formation of acetate and ATP from acetyl-CoA by using ADP and phosphate, and a C-terminal domain that may catalyze the transfer of an acetyl group from acetyl-CoA to a substrate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
1-702 0e+00

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


:

Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 883.70  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961   1 MSQRGLEALLRPKSIAVIGASMKPDRAGYLMMRNLLSGGFNGPVMPVTPAYKAVQGVLAWPDVQSLPFVPDLAVLCTHAK 80
Cdd:COG1042    1 MSTRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  81 RNLELLESLGQKGCKTCIILSSP--------PEQQPELLACASRYQMRILGPNSLGLLAPWQGLNASFSPVPIRKGKLAF 152
Cdd:COG1042   81 TVPDVVEECGEKGVKAAVVISAGfaetgeegAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPVPPLPGNIAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 153 ISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDFLARDSKTSAILLYLEHLSDARRFVSASRSASRNKPILV 232
Cdd:COG1042  161 VSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAARGKPVVV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 233 IKSGRSPAAQRLLQSHSGM----DPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGEKLMIVSNGAAPAALALDEL 308
Cdd:COG1042  241 LKSGRSEAGARAAASHTGAlagsDAVYDAAFRRAGVIRVDDLEELFDAAEALARQPPPRGRRLAIVTNSGGPGVLAADAL 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 309 WLRNGKLATLGEETLQRLRDALPGSVVPDNPLDLRDDASSDRYIKAITILLDSQDFDALMIIHSPSAVAPGSESARTLIE 388
Cdd:COG1042  321 EDLGLELAELSEETQAALRAVLPPFASVGNPVDITGDADPERYAAALEALLADPNVDAVLVILTPTAMTDPEEVAEALIE 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 389 AVRNHPRgkyvTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPAlPGNLTANSVDVHS 468
Cdd:COG1042  401 AAKGSGK----PVLASWMGGDSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPA-SEDFDPDRERARA 475

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 469 LLQQAIEEGATSLDTHEVQPILGSYGMQTLPTWIAGDSAEAVHIAEQIGYPVALKLRSPDIPHKSDVQGVMLYLRTATEV 548
Cdd:COG1042  476 IIEAALAEGRGVLTEAEAKALLAAYGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRDAEAV 555

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 549 QQAADAIIDRVKMTWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAAVALPPLNMNLARY 628
Cdd:COG1042  556 RAAFEEILARVRAARPDARIDGVLVQPMVP--GGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNEALARE 633

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 550756961 629 LVIQAIKSKKIRGRSALRPLDIAGLSQFLVKVSNLIVDCAEIQRLDIHPLLASGNEFTALDVTLEIAPFVGDRE 702
Cdd:COG1042  634 MIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLPEILELDINPLLVVPEGVVAVDARIRLAPPAPPAP 707
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 722-863 1.11e-15

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 75.81  E-value: 1.11e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 722 NGERALFRPILPEDEPLLRAFISQvtKEDLYYRYFSEIN-EFTHDDLANMTQIDYDREMAIVAVRRSAEGEeILGVTRAI 800
Cdd:COG1670    4 ETERLRLRPLRPEDAEALAELLND--PEVARYLPGPPYSlEEARAWLERLLADWADGGALPFAIEDKEDGE-LIGVVGLY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550756961 801 S-DPDNVDAEFAVLVRSDLKGLGLGRRLLEKLIGYTRDH-GLSRLNGITMPNNRGMVTLARKLGF 863
Cdd:COG1670   81 DiDRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGF 145
 
Name Accession Description Interval E-value
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
1-702 0e+00

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 883.70  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961   1 MSQRGLEALLRPKSIAVIGASMKPDRAGYLMMRNLLSGGFNGPVMPVTPAYKAVQGVLAWPDVQSLPFVPDLAVLCTHAK 80
Cdd:COG1042    1 MSTRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  81 RNLELLESLGQKGCKTCIILSSP--------PEQQPELLACASRYQMRILGPNSLGLLAPWQGLNASFSPVPIRKGKLAF 152
Cdd:COG1042   81 TVPDVVEECGEKGVKAAVVISAGfaetgeegAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPVPPLPGNIAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 153 ISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDFLARDSKTSAILLYLEHLSDARRFVSASRSASRNKPILV 232
Cdd:COG1042  161 VSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAARGKPVVV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 233 IKSGRSPAAQRLLQSHSGM----DPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGEKLMIVSNGAAPAALALDEL 308
Cdd:COG1042  241 LKSGRSEAGARAAASHTGAlagsDAVYDAAFRRAGVIRVDDLEELFDAAEALARQPPPRGRRLAIVTNSGGPGVLAADAL 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 309 WLRNGKLATLGEETLQRLRDALPGSVVPDNPLDLRDDASSDRYIKAITILLDSQDFDALMIIHSPSAVAPGSESARTLIE 388
Cdd:COG1042  321 EDLGLELAELSEETQAALRAVLPPFASVGNPVDITGDADPERYAAALEALLADPNVDAVLVILTPTAMTDPEEVAEALIE 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 389 AVRNHPRgkyvTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPAlPGNLTANSVDVHS 468
Cdd:COG1042  401 AAKGSGK----PVLASWMGGDSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPA-SEDFDPDRERARA 475

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 469 LLQQAIEEGATSLDTHEVQPILGSYGMQTLPTWIAGDSAEAVHIAEQIGYPVALKLRSPDIPHKSDVQGVMLYLRTATEV 548
Cdd:COG1042  476 IIEAALAEGRGVLTEAEAKALLAAYGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRDAEAV 555

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 549 QQAADAIIDRVKMTWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAAVALPPLNMNLARY 628
Cdd:COG1042  556 RAAFEEILARVRAARPDARIDGVLVQPMVP--GGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNEALARE 633

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 550756961 629 LVIQAIKSKKIRGRSALRPLDIAGLSQFLVKVSNLIVDCAEIQRLDIHPLLASGNEFTALDVTLEIAPFVGDRE 702
Cdd:COG1042  634 MIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLPEILELDINPLLVVPEGVVAVDARIRLAPPAPPAP 707
AcCoA-syn-alpha TIGR02717
acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it ...
 6-443 3.50e-135

acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.


Pssm-ID: 131764 [Multi-domain]  Cd Length: 447  Bit Score: 410.93  E-value: 3.50e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961    6 LEALLRPKSIAVIGASMKPDRAGYLMMRNLLSGGFNGPVMPVTPAYKAVQGVLAWPDVQSLPFVPDLAVLCTHAKRNLEL 85
Cdd:TIGR02717   1 LEHLFNPKSVAVIGASRDPGKVGYAIMKNLIEGGYKGKIYPVNPKAGEILGVKAYPSVLEIPDPVDLAVIVVPAKYVPQV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961   86 LESLGQKGCKTCIILSS--------PPEQQPELLACASRYQMRILGPNSLGLLAPWQGLNASFSPVPIRKGKLAFISQSA 157
Cdd:TIGR02717  81 VEECGEKGVKGAVVITAgfkevgeeGAELEQELVEIARKYGMRLLGPNCLGIINTHIKLNATFAPTMPKKGGIAFISQSG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  158 AVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDFLARDSKTSAILLYLEHLSDARRFVSASRSASRNKPILVIKSGR 237
Cdd:TIGR02717 161 ALLTALLDWAEKNGVGFSYFVSLGNKADIDESDLLEYLADDPDTKVILLYLEGIKDGRKFLKTAREISKKKPIVVLKSGT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  238 SPAAQRLLQSHSGM----DPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGEKLMIVSNGAAPAALALDELWLRNG 313
Cdd:TIGR02717 241 SEAGAKAASSHTGAlagsDEAYDAAFKQAGVIRADSIEELFDLARLLSNQPLPKGNRVAIITNAGGPGVIATDACEENGL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  314 KLATLGEETLQRLRDALPGSVVPDNPLDLRDDASSDRYIKAITILLDSQDFDALMIIHSPSAVAPGSESARTLIEAVRNH 393
Cdd:TIGR02717 321 ELAELSEATKNKLRNILPPEASIKNPVDVLGDATPERYAKALKTVAEDENVDGVVVVLTPTAMTDPEEVAKGIIEGAKKS 400

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 550756961  394 PRgkyVTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYR 443
Cdd:TIGR02717 401 NE---KPVVAGFMGGKSVDPAKRILEENGIPNYTFPERAVKALSALYRYA 447
ATP-grasp_5 pfam13549
ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent ...
 472-694 2.55e-88

ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent carboxylate-amine ligase activity.


Pssm-ID: 463918 [Multi-domain]  Cd Length: 221  Bit Score: 279.75  E-value: 2.55e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  472 QAIEEGATSLDTHEVQPILGSYGMQTLPTWIAGDSAEAVHIAEQIGYPVALKLRSPDIPHKSDVQGVMLYLRTATEVQQA 551
Cdd:pfam13549   1 KALAEGRTVLTEPEAKALLAAYGIPVVPTRLARSPEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRSAEAVRAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  552 ADAIIDRVKMTWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAAVALPPLNMNLARYLvI 631
Cdd:pfam13549  81 YEEILERVRRYRPDARIEGVLVQPMAP--GGRELIVGVTRDPQFGPVIMFGLGGIAVEVLKDVAFRLPPLNMTLAREM-I 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 550756961  632 QAIKSKKI-RGRSALRPLDIAGLSQFLVKVSNLIVDCAEIQRLDIHPLLASGNEFTALDVTLEI 694
Cdd:pfam13549 158 RRTRAYKLlKGYRGEPPADLDALEDVLVRVSQLVIDFPEIRELDINPLLADEDGVVALDARIRL 221
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 722-863 1.11e-15

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 75.81  E-value: 1.11e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 722 NGERALFRPILPEDEPLLRAFISQvtKEDLYYRYFSEIN-EFTHDDLANMTQIDYDREMAIVAVRRSAEGEeILGVTRAI 800
Cdd:COG1670    4 ETERLRLRPLRPEDAEALAELLND--PEVARYLPGPPYSlEEARAWLERLLADWADGGALPFAIEDKEDGE-LIGVVGLY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550756961 801 S-DPDNVDAEFAVLVRSDLKGLGLGRRLLEKLIGYTRDH-GLSRLNGITMPNNRGMVTLARKLGF 863
Cdd:COG1670   81 DiDRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGF 145
CoA_binding smart00881
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 9-102 1.18e-14

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 214881 [Multi-domain]  Cd Length: 100  Bit Score: 70.23  E-value: 1.18e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961     9 LLRP-KSIAVIGASMKPDRAGYLMMRNLLSGG--FNGPVMPVtPAYKAVQGVLAWPDVQSLPFV--PDLAVLCTHAKRNL 83
Cdd:smart00881   1 LLNPnTSVAVVGASGNLGSFGLAVMRNLLEYGtkFVGGVYPG-KVGPKVDGVPVYDSVAEAPEEtgVDVAVIFVPAEAAP 79

                           90
                   ....*....|....*....
gi 550756961    84 ELLESLGQKGCKTCIILSS 102
Cdd:smart00881  80 DAIDEAIEAGIKGIVVITE 98
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 750-863 5.37e-09

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 54.83  E-value: 5.37e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  750 DLYYRYFSEinEFTHDDLANMTQIDYDREMAIVAVRrsaEGEEILGVTRA--ISDPDNVDAEFAVLVRSDLKGLGLGRRL 827
Cdd:pfam00583   6 ELLSEEFPE--PWPDEPLDLLEDWDEDASEGFFVAE---EDGELVGFASLsiIDDEPPVGEIEGLAVAPEYRGKGIGTAL 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 550756961  828 LEKLIGYTRDHGLSRLNGITMPNNRGMVTLARKLGF 863
Cdd:pfam00583  81 LQALLEWARERGCERIFLEVAADNLAAIALYEKLGF 116
 
Name Accession Description Interval E-value
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
1-702 0e+00

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 883.70  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961   1 MSQRGLEALLRPKSIAVIGASMKPDRAGYLMMRNLLSGGFNGPVMPVTPAYKAVQGVLAWPDVQSLPFVPDLAVLCTHAK 80
Cdd:COG1042    1 MSTRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  81 RNLELLESLGQKGCKTCIILSSP--------PEQQPELLACASRYQMRILGPNSLGLLAPWQGLNASFSPVPIRKGKLAF 152
Cdd:COG1042   81 TVPDVVEECGEKGVKAAVVISAGfaetgeegAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPVPPLPGNIAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 153 ISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDFLARDSKTSAILLYLEHLSDARRFVSASRSASRNKPILV 232
Cdd:COG1042  161 VSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAARGKPVVV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 233 IKSGRSPAAQRLLQSHSGM----DPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGEKLMIVSNGAAPAALALDEL 308
Cdd:COG1042  241 LKSGRSEAGARAAASHTGAlagsDAVYDAAFRRAGVIRVDDLEELFDAAEALARQPPPRGRRLAIVTNSGGPGVLAADAL 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 309 WLRNGKLATLGEETLQRLRDALPGSVVPDNPLDLRDDASSDRYIKAITILLDSQDFDALMIIHSPSAVAPGSESARTLIE 388
Cdd:COG1042  321 EDLGLELAELSEETQAALRAVLPPFASVGNPVDITGDADPERYAAALEALLADPNVDAVLVILTPTAMTDPEEVAEALIE 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 389 AVRNHPRgkyvTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPAlPGNLTANSVDVHS 468
Cdd:COG1042  401 AAKGSGK----PVLASWMGGDSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPA-SEDFDPDRERARA 475

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 469 LLQQAIEEGATSLDTHEVQPILGSYGMQTLPTWIAGDSAEAVHIAEQIGYPVALKLRSPDIPHKSDVQGVMLYLRTATEV 548
Cdd:COG1042  476 IIEAALAEGRGVLTEAEAKALLAAYGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRDAEAV 555

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 549 QQAADAIIDRVKMTWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAAVALPPLNMNLARY 628
Cdd:COG1042  556 RAAFEEILARVRAARPDARIDGVLVQPMVP--GGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNEALARE 633

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 550756961 629 LVIQAIKSKKIRGRSALRPLDIAGLSQFLVKVSNLIVDCAEIQRLDIHPLLASGNEFTALDVTLEIAPFVGDRE 702
Cdd:COG1042  634 MIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLPEILELDINPLLVVPEGVVAVDARIRLAPPAPPAP 707
AcCoA-syn-alpha TIGR02717
acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it ...
 6-443 3.50e-135

acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.


Pssm-ID: 131764 [Multi-domain]  Cd Length: 447  Bit Score: 410.93  E-value: 3.50e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961    6 LEALLRPKSIAVIGASMKPDRAGYLMMRNLLSGGFNGPVMPVTPAYKAVQGVLAWPDVQSLPFVPDLAVLCTHAKRNLEL 85
Cdd:TIGR02717   1 LEHLFNPKSVAVIGASRDPGKVGYAIMKNLIEGGYKGKIYPVNPKAGEILGVKAYPSVLEIPDPVDLAVIVVPAKYVPQV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961   86 LESLGQKGCKTCIILSS--------PPEQQPELLACASRYQMRILGPNSLGLLAPWQGLNASFSPVPIRKGKLAFISQSA 157
Cdd:TIGR02717  81 VEECGEKGVKGAVVITAgfkevgeeGAELEQELVEIARKYGMRLLGPNCLGIINTHIKLNATFAPTMPKKGGIAFISQSG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  158 AVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDFLARDSKTSAILLYLEHLSDARRFVSASRSASRNKPILVIKSGR 237
Cdd:TIGR02717 161 ALLTALLDWAEKNGVGFSYFVSLGNKADIDESDLLEYLADDPDTKVILLYLEGIKDGRKFLKTAREISKKKPIVVLKSGT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  238 SPAAQRLLQSHSGM----DPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGEKLMIVSNGAAPAALALDELWLRNG 313
Cdd:TIGR02717 241 SEAGAKAASSHTGAlagsDEAYDAAFKQAGVIRADSIEELFDLARLLSNQPLPKGNRVAIITNAGGPGVIATDACEENGL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  314 KLATLGEETLQRLRDALPGSVVPDNPLDLRDDASSDRYIKAITILLDSQDFDALMIIHSPSAVAPGSESARTLIEAVRNH 393
Cdd:TIGR02717 321 ELAELSEATKNKLRNILPPEASIKNPVDVLGDATPERYAKALKTVAEDENVDGVVVVLTPTAMTDPEEVAKGIIEGAKKS 400

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 550756961  394 PRgkyVTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYR 443
Cdd:TIGR02717 401 NE---KPVVAGFMGGKSVDPAKRILEENGIPNYTFPERAVKALSALYRYA 447
ATP-grasp_5 pfam13549
ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent ...
 472-694 2.55e-88

ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent carboxylate-amine ligase activity.


Pssm-ID: 463918 [Multi-domain]  Cd Length: 221  Bit Score: 279.75  E-value: 2.55e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  472 QAIEEGATSLDTHEVQPILGSYGMQTLPTWIAGDSAEAVHIAEQIGYPVALKLRSPDIPHKSDVQGVMLYLRTATEVQQA 551
Cdd:pfam13549   1 KALAEGRTVLTEPEAKALLAAYGIPVVPTRLARSPEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRSAEAVRAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  552 ADAIIDRVKMTWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAAVALPPLNMNLARYLvI 631
Cdd:pfam13549  81 YEEILERVRRYRPDARIEGVLVQPMAP--GGRELIVGVTRDPQFGPVIMFGLGGIAVEVLKDVAFRLPPLNMTLAREM-I 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 550756961  632 QAIKSKKI-RGRSALRPLDIAGLSQFLVKVSNLIVDCAEIQRLDIHPLLASGNEFTALDVTLEI 694
Cdd:pfam13549 158 RRTRAYKLlKGYRGEPPADLDALEDVLVRVSQLVIDFPEIRELDINPLLADEDGVVALDARIRL 221
Succ_CoA_lig pfam13607
Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from ...
 147-280 3.11e-54

Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from Succinyl-CoA ligase alpha subunit and other related enzymes. A conserved histidine is involved in phosphoryl transfer.


Pssm-ID: 433345 [Multi-domain]  Cd Length: 138  Bit Score: 184.21  E-value: 3.11e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  147 KGKLAFISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDFLARDSKTSAILLYLEHLSDARRFVSASRSASR 226
Cdd:pfam13607   1 PGNIALVSQSGALGAALLDWARSRGIGFSKFVSLGNEADVDFADLLEYLADDPETRVILLYLEGIRDGRRFLRAARRAAR 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 550756961  227 NKPILVIKSGRSPAAQRLLQSH----SGMDPAWDAAIQRAGLLRVQDTHELFSAVETL 280
Cdd:pfam13607  81 RKPVVVLKAGRSEAGARAAASHtgalAGSDAVYDAAFRQAGVIRVDDLEELFDAAEAL 138
CoA_binding_2 pfam13380
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 13-132 4.55e-28

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 433162 [Multi-domain]  Cd Length: 116  Bit Score: 109.17  E-value: 4.55e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961   13 KSIAVIGASMKPDRAGYLMMRNLLSGGFngPVMPVTPAYKAVQGVLAWPDVQSLPFVPDLAVLCTHAKRNLELLESLGQK 92
Cdd:pfam13380   1 KTIAVVGASPNPGRPGYKVARYLLEHGY--PVIPVNPKAKEILGEPVYPSLADPPEPVDLVDVFRPPEAVPEIVEEALAL 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 550756961   93 GCKTCIILSSppEQQPELLACASRYQMRILGPNSLGLLAP 132
Cdd:pfam13380  79 GAKAVWLQPG--IENEEAAAIARAAGIRVVGDRCLGVEHP 116
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 722-863 1.11e-15

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 75.81  E-value: 1.11e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 722 NGERALFRPILPEDEPLLRAFISQvtKEDLYYRYFSEIN-EFTHDDLANMTQIDYDREMAIVAVRRSAEGEeILGVTRAI 800
Cdd:COG1670    4 ETERLRLRPLRPEDAEALAELLND--PEVARYLPGPPYSlEEARAWLERLLADWADGGALPFAIEDKEDGE-LIGVVGLY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 550756961 801 S-DPDNVDAEFAVLVRSDLKGLGLGRRLLEKLIGYTRDH-GLSRLNGITMPNNRGMVTLARKLGF 863
Cdd:COG1670   81 DiDRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGF 145
CoA_binding smart00881
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 9-102 1.18e-14

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 214881 [Multi-domain]  Cd Length: 100  Bit Score: 70.23  E-value: 1.18e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961     9 LLRP-KSIAVIGASMKPDRAGYLMMRNLLSGG--FNGPVMPVtPAYKAVQGVLAWPDVQSLPFV--PDLAVLCTHAKRNL 83
Cdd:smart00881   1 LLNPnTSVAVVGASGNLGSFGLAVMRNLLEYGtkFVGGVYPG-KVGPKVDGVPVYDSVAEAPEEtgVDVAVIFVPAEAAP 79

                           90
                   ....*....|....*....
gi 550756961    84 ELLESLGQKGCKTCIILSS 102
Cdd:smart00881  80 DAIDEAIEAGIKGIVVITE 98
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
728-863 3.15e-14

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 71.18  E-value: 3.15e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 728 FRPILPEDEPLLRAFISQVTKEDLYyRYFSEinEFTHDDLAN-MTQIDYDREMAIVAVrrsaEGEEILGVTRAIS----D 802
Cdd:COG1247    4 IRPATPEDAPAIAAIYNEAIAEGTA-TFETE--PPSEEEREAwFAAILAPGRPVLVAE----EDGEVVGFASLGPfrprP 76

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 550756961 803 PDNVDAEFAVLVRSDLKGLGLGRRLLEKLIGYTRDHGLSRLNGITMPNNRGMVTLARKLGF 863
Cdd:COG1247   77 AYRGTAEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLADNEASIALYEKLGF 137
YccU COG1832
Predicted CoA-binding protein [General function prediction only];
7-72 2.87e-09

Predicted CoA-binding protein [General function prediction only];


Pssm-ID: 441437 [Multi-domain]  Cd Length: 138  Bit Score: 56.29  E-value: 2.87e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550756961   7 EALLRPKSIAVIGASMKPDRAGYLMMRNLLSGGFNgpVMPVTPAYKAVQGVLAWPDVQSLPFVPDL 72
Cdd:COG1832   11 EILKSAKTIAVVGLSPNPERPSYYVAKYLQRHGYR--VIPVNPGAKEILGEKVYASLADIPEPVDI 74
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 750-863 5.37e-09

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 54.83  E-value: 5.37e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  750 DLYYRYFSEinEFTHDDLANMTQIDYDREMAIVAVRrsaEGEEILGVTRA--ISDPDNVDAEFAVLVRSDLKGLGLGRRL 827
Cdd:pfam00583   6 ELLSEEFPE--PWPDEPLDLLEDWDEDASEGFFVAE---EDGELVGFASLsiIDDEPPVGEIEGLAVAPEYRGKGIGTAL 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 550756961  828 LEKLIGYTRDHGLSRLNGITMPNNRGMVTLARKLGF 863
Cdd:pfam00583  81 LQALLEWARERGCERIFLEVAADNLAAIALYEKLGF 116
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 725-863 6.37e-07

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 49.65  E-value: 6.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961  725 RALFRPILPEDEPLLRAFISQvtKEDLYYRYFSEIN-EFTHDDLANMTQIDYDREMAIVAVRRSAEGEeiLGVTRAIS-D 802
Cdd:pfam13302   1 RLLLRPLTEEDAEALFELLSD--PEVMRYGVPWPLTlEEAREWLARIWAADEAERGYGWAIELKDTGF--IGSIGLYDiD 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 550756961  803 PDNVDAEFAVLVRSDLKGLGLGRRLLEKLIGYT-RDHGLSRLNGITMPNNRGMVTLARKLGF 863
Cdd:pfam13302  77 GEPERAELGYWLGPDYWGKGYATEAVRALLEYAfEELGLPRLVARIDPENTASRRVLEKLGF 138
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 814-863 1.24e-05

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 44.65  E-value: 1.24e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 550756961 814 VRSDLKGLGLGRRLLEKLIGYTRDHGLSRLNGITMPNNRGMVTLARKLGF 863
Cdd:COG0456   21 VDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALYEKLGF 70
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
728-863 1.30e-04

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 42.77  E-value: 1.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 728 FRPILPEDEPLLRAfisqvtkedLYYRYFSEINEfthDDLANMTQIDYDREMAIVAVrrsaEGEEILGVTRAISDPDNVD 807
Cdd:COG3153    1 IRPATPEDAEAIAA---------LLRAAFGPGRE---AELVDRLREDPAAGLSLVAE----DDGEIVGHVALSPVDIDGE 64

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 808 AEFAVL----VRSDLKGLGLGRRLLEKLIGYTRDHGLSRLNGITMPNNRGmvtLARKLGF 863
Cdd:COG3153   65 GPALLLgplaVDPEYRGQGIGRALMRAALEAARERGARAVVLLGDPSLLP---FYERFGF 121
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 728-865 2.34e-04

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 41.96  E-value: 2.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 728 FRPILPEDEPLLRAFisqvtkedlyyryfseinEFTHDDLANMTQIDYDREMAIVAVRRSAEGeeiLGVTRAISDPDnvd 807
Cdd:COG0454    3 IRKATPEDINFILLI------------------EALDAELKAMEGSLAGAEFIAVDDKGEPIG---FAGLRRLDDKV--- 58

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 550756961 808 AEFAVL-VRSDLKGLGLGRRLLEKLIGYTRDHGLSRLNGITMPNNRGMVTLARKLGFDV 865
Cdd:COG0454   59 LELKRLyVLPEYRGKGIGKALLEALLEWARERGCTALELDTLDGNPAAIRFYERLGFKE 117
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 789-863 9.20e-04

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 40.36  E-value: 9.20e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 550756961 789 EGEEILGVTRAISDPDNVdAEFA-VLVRSDLKGLGLGRRLLEKLIGYTRDHGLSRLNGITMPNNRGmvtLARKLGF 863
Cdd:COG1246   35 EDGEIVGCAALHPLDEDL-AELRsLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLTTSAAIH---FYEKLGF 106
SucD COG0074
Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA ...
 109-207 1.14e-03

Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA synthetase, alpha subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 439844 [Multi-domain]  Cd Length: 288  Bit Score: 41.97  E-value: 1.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 109 ELLACASRYQMRILGPNSLGLLAPWQgLNASFSPVPI-RKGKLAFISQSAAVSNTILDWAQQREMGFSYFIALG-DSL-D 185
Cdd:COG0074  106 RVKRYAKAKGTRLIGPNCPGIITPGE-CKLGIMPGHIfKPGRVGIVSRSGTLTYEAVWQLTQAGLGQSTCVGIGgDPIiG 184

                         90       100
                 ....*....|....*....|..
gi 550756961 186 IDVDELLDFLARDSKTSAILLY 207
Cdd:COG0074  185 TSFIDVLELFEEDPETEAIVMI 206
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
792-863 4.23e-03

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 37.20  E-value: 4.23e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 550756961 792 EILGVTRAISDPDNVDAEFAVLVRSDLKGLGLGRRLLEKLIGYTRDHGLSRLNGITMPNNRGMVTLARKLGF 863
Cdd:COG3393    1 ELVAMAGVRAESPGVAEISGVYTHPEYRGRGLASALVAALAREALARGARTPFLYVDADNPAARRLYERLGF 72
SucC COG0045
Succinyl-CoA synthetase, beta subunit [Energy production and conversion]; Succinyl-CoA ...
 484-689 6.42e-03

Succinyl-CoA synthetase, beta subunit [Energy production and conversion]; Succinyl-CoA synthetase, beta subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 439815 [Multi-domain]  Cd Length: 388  Bit Score: 40.03  E-value: 6.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 484 HEVQ--PILGSYGMQTLPTWIAGDSAEAVHIAEQIGY-PVALKlrspdiphksdVQ----------GVMLyLRTATEVQQ 550
Cdd:COG0045    4 HEYQakELLAKYGVPVPRGIVATTPEEAVAAAEELGGpPVVVK-----------AQvhaggrgkagGVKL-AKSPEEARE 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 550756961 551 AADAIIDRV---KMTWPQAR-IHGLLVQSMANraGAQELRVVVEHDPVFG-PLIML-GEGGVEW------RPEEQAAVAL 618
Cdd:COG0045   72 AAEEILGMTlvtHQTGPKGKpVNKVLVEEGVD--IAKELYLSILLDRATRrPVIMAsTEGGMDIeevaeeTPEKIIKVPI 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 550756961 619 PPLnMNLARYlviQAiksKKIRGRSALRPLDIAGLSQFLVKVSNLIVDC-AEIqrLDIHPL-LASGNEFTALD 689
Cdd:COG0045  150 DPL-VGLQPY---QA---RELAFALGLPGKQVKQFAKILKKLYRAFVEKdASL--VEINPLvVTKDGRLVALD 213
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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