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Conserved domains on  [gi|553795424|ref|WP_023126083|]
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MULTISPECIES: class I SAM-dependent methyltransferase [Pseudomonas]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 11423066)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor; similar to Saccharomyces cerevisiae trans-aconitate 3-methyltransferase

CATH:  3.40.50.150
EC:  2.1.1.-
Gene Ontology:  GO:1904047|GO:0008168|GO:0032259|GO:0008757
PubMed:  12826405|12504684
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 27-137 4.74e-15

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


:

Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 70.72  E-value: 4.74e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  27 HLLSRAQLLARLPERARLLSVGCGAGGELAELAGlRPGWRFVAADLSADMLALAHQRCARLGlLERIELHCGDVAGLP-- 104
Cdd:COG0500   13 GLAALLALLERLPKGGRVLDLGCGTGRNLLALAA-RFGGRVIGIDLSPEAIALARARAAKAG-LGNVEFLVADLAELDpl 90

                         90       100       110
                 ....*....|....*....|....*....|...
gi 553795424 105 PAPPCDAALVLLVLHFLrgDQAKRRFLEAVAER 137
Cdd:COG0500   91 PAESFDLVVAFGVLHHL--PPEEREALLRELAR 121
 
Name Accession Description Interval E-value
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 27-137 4.74e-15

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 70.72  E-value: 4.74e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  27 HLLSRAQLLARLPERARLLSVGCGAGGELAELAGlRPGWRFVAADLSADMLALAHQRCARLGlLERIELHCGDVAGLP-- 104
Cdd:COG0500   13 GLAALLALLERLPKGGRVLDLGCGTGRNLLALAA-RFGGRVIGIDLSPEAIALARARAAKAG-LGNVEFLVADLAELDpl 90

                         90       100       110
                 ....*....|....*....|....*....|...
gi 553795424 105 PAPPCDAALVLLVLHFLrgDQAKRRFLEAVAER 137
Cdd:COG0500   91 PAESFDLVVAFGVLHHL--PPEEREALLRELAR 121
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 47-135 4.68e-13

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 62.58  E-value: 4.68e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424   47 VGCGAGGELAELAGlRPGWRFVAADLSADMLALAHQRCARLGLleRIELHCGDVAGLPPAP-PCDAALVLLVLHFLrGDQ 125
Cdd:pfam13649   4 LGCGTGRLTLALAR-RGGARVTGVDLSPEMLERARERAAEAGL--NVEFVQGDAEDLPFPDgSFDLVVSSGVLHHL-PDP 79

                          90
                  ....*....|
gi 553795424  126 AKRRFLEAVA 135
Cdd:pfam13649  80 DLEAALREIA 89
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 43-137 3.19e-09

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 52.82  E-value: 3.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  43 RLLSVGCGAGGELAELAgLRPGWRFVAADLSADMLALAhQRCARLGLLERIELHCGDVAGLPPAPP--CDAALVLLVLHF 120
Cdd:cd02440    1 RVLDLGCGTGALALALA-SGPGARVTGVDISPVALELA-RKAAAALLADNVEVLKGDAEELPPEADesFDVIISDPPLHH 78

                         90
                 ....*....|....*..
gi 553795424 121 LRGDQakRRFLEAVAER 137
Cdd:cd02440   79 LVEDL--ARFLEEARRL 93
PRK08317 PRK08317
hypothetical protein; Provisional
 30-121 6.85e-09

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 54.17  E-value: 6.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  30 SRAQLLARLPERArlLSVGCGAGGELAELAGL-RPGWRFVAADLSADMLALAHQRCARLGLleRIELHCGDVAGLP-PAP 107
Cdd:PRK08317  11 TFELLAVQPGDRV--LDVGCGPGNDARELARRvGPEGRVVGIDRSEAMLALAKERAAGLGP--NVEFVRGDADGLPfPDG 86

                         90
                 ....*....|....
gi 553795424 108 PCDAALVLLVLHFL 121
Cdd:PRK08317  87 SFDAVRSDRVLQHL 100
PKS_MT smart00828
Methyltransferase in polyketide synthase (PKS) enzymes;
43-122 2.00e-06

Methyltransferase in polyketide synthase (PKS) enzymes;


Pssm-ID: 214839 [Multi-domain]  Cd Length: 224  Bit Score: 47.03  E-value: 2.00e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424    43 RLLSVGCGAGGELAELAGLRPGWRFVAADLSADMLALAHQRCARLGLLERIELHCGDVAGLPPAPPCDAALVLLVLHFLR 122
Cdd:smart00828   2 RVLDFGCGYGSDLIDLAERHPHLQLHGYTISPEQAEVGRERIRALGLQGRIRIFYRDSAKDPFPDTYDLVFGFEVIHHIK 81
 
Name Accession Description Interval E-value
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 27-137 4.74e-15

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 70.72  E-value: 4.74e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  27 HLLSRAQLLARLPERARLLSVGCGAGGELAELAGlRPGWRFVAADLSADMLALAHQRCARLGlLERIELHCGDVAGLP-- 104
Cdd:COG0500   13 GLAALLALLERLPKGGRVLDLGCGTGRNLLALAA-RFGGRVIGIDLSPEAIALARARAAKAG-LGNVEFLVADLAELDpl 90

                         90       100       110
                 ....*....|....*....|....*....|...
gi 553795424 105 PAPPCDAALVLLVLHFLrgDQAKRRFLEAVAER 137
Cdd:COG0500   91 PAESFDLVVAFGVLHHL--PPEEREALLRELAR 121
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
42-135 1.41e-13

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 64.07  E-value: 1.41e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  42 ARLLSVGCGAGGELAELAGLRPGWRFVAADLSADMLALAHQRcarlglLERIELHCGDVAGLPPAPPCDAALVLLVLHFL 121
Cdd:COG4106    3 RRVLDLGCGTGRLTALLAERFPGARVTGVDLSPEMLARARAR------LPNVRFVVADLRDLDPPEPFDLVVSNAALHWL 76

                         90
                 ....*....|....*.
gi 553795424 122 RgDQAK--RRFLEAVA 135
Cdd:COG4106   77 P-DHAAllARLAAALA 91
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 31-126 4.67e-13

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 64.24  E-value: 4.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  31 RAQLLARLPER--ARLLSVGCGAGGELAELAglRPGWRFVAADLSADMLALAHQRCARLGLleRIELHCGDVAGLP-PAP 107
Cdd:COG2226   11 REALLAALGLRpgARVLDLGCGTGRLALALA--ERGARVTGVDISPEMLELARERAAEAGL--NVEFVVGDAEDLPfPDG 86

                         90
                 ....*....|....*....
gi 553795424 108 PCDAALVLLVLHFLRGDQA 126
Cdd:COG2226   87 SFDLVISSFVLHHLPDPER 105
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 47-135 4.68e-13

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 62.58  E-value: 4.68e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424   47 VGCGAGGELAELAGlRPGWRFVAADLSADMLALAHQRCARLGLleRIELHCGDVAGLPPAP-PCDAALVLLVLHFLrGDQ 125
Cdd:pfam13649   4 LGCGTGRLTLALAR-RGGARVTGVDLSPEMLERARERAAEAGL--NVEFVQGDAEDLPFPDgSFDLVVSSGVLHHL-PDP 79

                          90
                  ....*....|
gi 553795424  126 AKRRFLEAVA 135
Cdd:pfam13649  80 DLEAALREIA 89
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 36-137 1.47e-12

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 63.02  E-value: 1.47e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  36 ARLPERARLLSVGCGAGGeLAELAGLRPGWRFVAADLSADMLALAHQRCARLGLLERIELHCGDVAGLPPAPPCDAALVL 115
Cdd:COG2230   47 LGLKPGMRVLDIGCGWGG-LALYLARRYGVRVTGVTLSPEQLEYARERAAEAGLADRVEVRLADYRDLPADGQFDAIVSI 125

                         90       100
                 ....*....|....*....|..
gi 553795424 116 LVLHFLrGDQAKRRFLEAVAER 137
Cdd:COG2230  126 GMFEHV-GPENYPAYFAKVARL 146
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 34-136 6.52e-11

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 57.72  E-value: 6.52e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  34 LLARLPERARLLSVGCGAGGELAELAGLrpGWRFVAADLSADMLALAHQRCARLglleRIELHCGDVAGLPPAP-PCDAA 112
Cdd:COG2227   18 LARLLPAGGRVLDVGCGTGRLALALARR--GADVTGVDISPEALEIARERAAEL----NVDFVQGDLEDLPLEDgSFDLV 91

                         90       100
                 ....*....|....*....|....
gi 553795424 113 LVLLVLHFLRGDQAkrrFLEAVAE 136
Cdd:COG2227   92 ICSEVLEHLPDPAA---LLRELAR 112
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 43-137 3.19e-09

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 52.82  E-value: 3.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  43 RLLSVGCGAGGELAELAgLRPGWRFVAADLSADMLALAhQRCARLGLLERIELHCGDVAGLPPAPP--CDAALVLLVLHF 120
Cdd:cd02440    1 RVLDLGCGTGALALALA-SGPGARVTGVDISPVALELA-RKAAAALLADNVEVLKGDAEELPPEADesFDVIISDPPLHH 78

                         90
                 ....*....|....*..
gi 553795424 121 LRGDQakRRFLEAVAER 137
Cdd:cd02440   79 LVEDL--ARFLEEARRL 93
PRK08317 PRK08317
hypothetical protein; Provisional
 30-121 6.85e-09

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 54.17  E-value: 6.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  30 SRAQLLARLPERArlLSVGCGAGGELAELAGL-RPGWRFVAADLSADMLALAHQRCARLGLleRIELHCGDVAGLP-PAP 107
Cdd:PRK08317  11 TFELLAVQPGDRV--LDVGCGPGNDARELARRvGPEGRVVGIDRSEAMLALAKERAAGLGP--NVEFVRGDADGLPfPDG 86

                         90
                 ....*....|....
gi 553795424 108 PCDAALVLLVLHFL 121
Cdd:PRK08317  87 SFDAVRSDRVLQHL 100
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 45-136 1.88e-08

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 50.44  E-value: 1.88e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424   45 LSVGCGAGGELAELAGLRPGWRFVAADLSADMLALAHQRCARLGLL--ERIELHCGDVAGLPPAPPcDAALVLLVLHFLR 122
Cdd:pfam08242   1 LEIGCGTGTLLRALLEALPGLEYTGLDISPAALEAARERLAALGLLnaVRVELFQLDLGELDPGSF-DVVVASNVLHHLA 79

                          90
                  ....*....|....
gi 553795424  123 GdqaKRRFLEAVAE 136
Cdd:pfam08242  80 D---PRAVLRNIRR 90
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
9-136 5.34e-08

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 51.15  E-value: 5.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424   9 ADGYETRIGRLLpGYELLHLLsRAQLLARLP--ERARLLSVGCGAGGELAELAGLrpGWRFVAADLSADMLALAHQRCAr 86
Cdd:COG4976   15 ADSYDAALVEDL-GYEAPALL-AEELLARLPpgPFGRVLDLGCGTGLLGEALRPR--GYRLTGVDLSEEMLAKAREKGV- 89

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 553795424  87 lglleRIELHCGDVAGLPPAP-PCDAALVLLVLHFLrGDQakRRFLEAVAE 136
Cdd:COG4976   90 -----YDRLLVADLADLAEPDgRFDLIVAADVLTYL-GDL--AAVFAGVAR 132
PRK07580 PRK07580
Mg-protoporphyrin IX methyl transferase; Validated
 31-99 1.05e-06

Mg-protoporphyrin IX methyl transferase; Validated


Pssm-ID: 236059 [Multi-domain]  Cd Length: 230  Bit Score: 47.91  E-value: 1.05e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 553795424  31 RAQLLARLPER-----ARLLSVGCGAGGELAELAglRPGWRFVAADLSADMLALAHQRCARLGLLERIELHCGD 99
Cdd:PRK07580  49 RDTVLSWLPADgdltgLRILDAGCGVGSLSIPLA--RRGAKVVASDISPQMVEEARERAPEAGLAGNITFEVGD 120
HemK COG2890
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ...
 27-110 1.19e-06

Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442135 [Multi-domain]  Cd Length: 282  Bit Score: 47.84  E-value: 1.19e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  27 HLLSRAQLLARLPERARLLSVGCGAGGELAELAGLRPGWRFVAADLSADMLALAHQRCARLGLLERIELHCGDV-AGLPP 105
Cdd:COG2890   99 ELVELALALLPAGAPPRVLDLGTGSGAIALALAKERPDARVTAVDISPDALAVARRNAERLGLEDRVRFLQGDLfEPLPG 178


                 ....*
gi 553795424 106 APPCD 110
Cdd:COG2890  179 DGRFD 183
PKS_MT smart00828
Methyltransferase in polyketide synthase (PKS) enzymes;
43-122 2.00e-06

Methyltransferase in polyketide synthase (PKS) enzymes;


Pssm-ID: 214839 [Multi-domain]  Cd Length: 224  Bit Score: 47.03  E-value: 2.00e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424    43 RLLSVGCGAGGELAELAGLRPGWRFVAADLSADMLALAHQRCARLGLLERIELHCGDVAGLPPAPPCDAALVLLVLHFLR 122
Cdd:smart00828   2 RVLDFGCGYGSDLIDLAERHPHLQLHGYTISPEQAEVGRERIRALGLQGRIRIFYRDSAKDPFPDTYDLVFGFEVIHHIK 81
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 45-121 2.67e-06

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 44.58  E-value: 2.67e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 553795424   45 LSVGCGAGGELAELAglRPGWRFVAADLSADMLALAHQRCARLGLleriELHCGDVAGLP-PAPPCDAALVLLVLHFL 121
Cdd:pfam08241   1 LDVGCGTGLLTELLA--RLGARVTGVDISPEMLELAREKAPREGL----TFVVGDAEDLPfPDNSFDLVLSSEVLHHV 72
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 36-104 1.01e-05

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 45.14  E-value: 1.01e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 553795424  36 ARLPERARLLSVGCGAG---GELAELAGlRPGWrFVAADLSADMLALAHQRCARLGLLERIELHCGDVAGLP 104
Cdd:PRK00216  47 LGVRPGDKVLDLACGTGdlaIALAKAVG-KTGE-VVGLDFSEGMLAVGREKLRDLGLSGNVEFVQGDAEALP 116
PRK09328 PRK09328
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
 27-100 4.30e-05

N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional


Pssm-ID: 236467 [Multi-domain]  Cd Length: 275  Bit Score: 43.23  E-value: 4.30e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 553795424  27 HLLSRAQLLARLPERARLLSVGCGAGGELAELAGLRPGWRFVAADLSADMLALAhQRCARLGLLERIELHCGDV 100
Cdd:PRK09328  95 ELVEWALEALLLKEPLRVLDLGTGSGAIALALAKERPDAEVTAVDISPEALAVA-RRNAKHGLGARVEFLQGDW 167
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 43-104 7.34e-05

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 41.63  E-value: 7.34e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 553795424   43 RLLSVGCGAGGELAELAG-LRPGWRFVAADLSADMLALAHQRCARLGlLERIELHCGDVAGLP 104
Cdd:pfam13847   6 RVLDLGCGTGHLSFELAEeLGPNAEVVGIDISEEAIEKARENAQKLG-FDNVEFEQGDIEELP 67
PRK14103 PRK14103
trans-aconitate 2-methyltransferase; Provisional
 34-123 1.11e-04

trans-aconitate 2-methyltransferase; Provisional


Pssm-ID: 184509  Cd Length: 255  Bit Score: 41.98  E-value: 1.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  34 LLARLPERA--RLLSVGCGAGGELAELAGLRPGWRFVAADLSADMLALAHQRcarlglleRIELHCGDVAGLPPAPPCDA 111
Cdd:PRK14103  21 LLARVGAERarRVVDLGCGPGNLTRYLARRWPGAVIEALDSSPEMVAAARER--------GVDARTGDVRDWKPKPDTDV 92

                         90
                 ....*....|..
gi 553795424 112 ALVLLVLHFLRG 123
Cdd:PRK14103  93 VVSNAALQWVPE 104
PRK11036 PRK11036
tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM;
33-97 1.30e-03

tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM;


Pssm-ID: 182918  Cd Length: 255  Bit Score: 38.79  E-value: 1.30e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 553795424  33 QLLARLPERA-RLLSVGCGAGGELAELAGLrpGWRFVAADLSADMLALAHQRCARLGLLERIEL-HC 97
Cdd:PRK11036  36 RLLAELPPRPlRVLDAGGGEGQTAIKLAEL--GHQVILCDLSAEMIQRAKQAAEAKGVSDNMQFiHC 100
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 35-108 1.72e-03

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 38.20  E-value: 1.72e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 553795424  35 LARLPERARLLSVGCGAGGELAELAGLRPGWRFVAADLSADMLALAHQRCARLGLLERIELHCGDVAGLPPAPP 108
Cdd:COG4123   32 FAPVKKGGRVLDLGTGTGVIALMLAQRSPGARITGVEIQPEAAELARRNVALNGLEDRITVIHGDLKEFAAELP 105
CMAS pfam02353
Mycolic acid cyclopropane synthetase; This family consist of ...
 36-95 2.72e-03

Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.


Pssm-ID: 396777 [Multi-domain]  Cd Length: 272  Bit Score: 38.08  E-value: 2.72e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424   36 ARLPERARLLSVGCGAGGeLAELAGLRPGWRFVAADLSADMLALAHQRCARLGLLERIEL 95
Cdd:pfam02353  57 LGLKPGMTLLDIGCGWGG-LMRRAAERYDVNVVGLTLSKNQYKLARKRVAAEGLARKVEV 115
PRK14966 PRK14966
unknown domain/N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase fusion protein; ...
 19-98 2.83e-03

unknown domain/N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase fusion protein; Provisional


Pssm-ID: 184930 [Multi-domain]  Cd Length: 423  Bit Score: 38.14  E-value: 2.83e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 553795424  19 LLPGYELLHLLSraQLLARLPERARLLSVGCGAGGELAELAGLRPGWRFVAADLSADMLALAHQRCARLGllERIELHCG 98
Cdd:PRK14966 232 LIPRPETEHLVE--AVLARLPENGRVWDLGTGSGAVAVTVALERPDAFVRASDISPPALETARKNAADLG--ARVEFAHG 307
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 24-99 4.47e-03

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 36.70  E-value: 4.47e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 553795424  24 ELLHLLSRAQllarlpeRA-RLLSVGCGAGGELAELA-GLRPGWRFVAADLSADMLALAHQRCARLGLLERIELHCGD 99
Cdd:COG4122    6 RLLYLLARLL-------GAkRILEIGTGTGYSTLWLArALPDDGRLTTIEIDPERAAIARENFARAGLADRIRLILGD 76
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 34-100 9.86e-03

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 35.94  E-value: 9.86e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 553795424  34 LLARLPERA--RLLSVGCGAGGELAELAGLRPGWRFVAADLSADMLALAHQRCARLGlLERIELHCGDV 100
Cdd:COG2813   41 LLEHLPEPLggRVLDLGCGYGVIGLALAKRNPEARVTLVDVNARAVELARANAAANG-LENVEVLWSDG 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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