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Conserved domains on  [gi|556300062|ref|WP_023292550|]
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MULTISPECIES: mannitol dehydrogenase family protein [Enterobacter]

Protein Classification

mannitol dehydrogenase family protein( domain architecture ID 11415531)

mannitol dehydrogenase family protein similar to Aspergillus fumigatus mannitol 2-dehydrogenase, which catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway

EC:  1.1.1.-
Gene Ontology:  GO:0016616
PubMed:  30945211
SCOP:  4000105

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MtlD COG0246
Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism];
6-485 0e+00

Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism];


:

Pssm-ID: 440016 [Multi-domain]  Cd Length: 492  Bit Score: 736.96  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062   6 LQANATLPQYDRDSLKARIVHLGFGAFHRAHQAVYADILAAEHGSDWGYCEVNLIGGEQQIADLNAQDNLYTVAEMSADA 85
Cdd:COG0246   12 LPAGVARPAYDRSALPPGIVHFGVGNFHRAHQAWYTDRLLNAGDFDWGIVGVGLRSGDALRDALAAQDGLYTLVERGPDG 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  86 -WTSRVVGVVKKALHAQVDGlETVLAAMCEPQVAIVSLTITEKGYCHSPATGQLMLDHPFIVADLQNPHQPKSAPGVVVE 164
Cdd:COG0246   92 vEEARVIGSISEVLVAPEDP-EAVLALLADPALRIVSLTITEKGYCLDPATGELDLDHPDIQADLANPAPPRSAPGKLTA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 165 ALARRKAAGLPAFSVMSCDNMPENGHVMRNVTCAYARAVDGELADWIESHVTFPSTMVDRIVPAVTPDTLDKIEQLTGVR 244
Cdd:COG0246  171 ALYRRRAAGLKPFTVLSCDNLPHNGDVLREAVLAFARLWDPELADWIEENVTFPNTMVDRIVPATTDEDRARLAAELGYE 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 245 DPAAVACEPFRQWVIEDNFVAGRPAWEKAGAELVSDVIPFEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDENYRVAA 324
Cdd:COG0246  251 DAAPVVAEPFRQWVIEDDFPAGRPPLEKAGVQFVDDVAPYEEMKLRLLNGSHTALAYLGYLAGYETVAEAMADPLLRAFV 330
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 325 HALMLNEQAPTLK-VKGVDLGRYADLLIARYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLVHQKPFPLLALGVAGWM 403
Cdd:COG0246  331 RRLMLEEIIPTLPpPPGVDLEAYADAVLERFANPAIRHTLARIALDGSQKLPQRLLPTLRDYLAAGRDPKRLALAVAAWL 410
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 404 RYVGGVDEQGNAIDVSDPQLAVIQAAVKGSAEGESRVRALLGIEAIFGKELPREAVFVDAVMKAYQTLLQKGAKATVAQY 483
Cdd:COG0246  411 RYLRGVDDDGEPIELSDPLADELAALAAAADDPADLVRAFLALEAIFGDDLADDPGFVEAVTAALEELLAKGARATLAAL 490

                 ..
gi 556300062 484 VS 485
Cdd:COG0246  491 LA 492
 
Name Accession Description Interval E-value
MtlD COG0246
Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism];
6-485 0e+00

Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism];


Pssm-ID: 440016 [Multi-domain]  Cd Length: 492  Bit Score: 736.96  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062   6 LQANATLPQYDRDSLKARIVHLGFGAFHRAHQAVYADILAAEHGSDWGYCEVNLIGGEQQIADLNAQDNLYTVAEMSADA 85
Cdd:COG0246   12 LPAGVARPAYDRSALPPGIVHFGVGNFHRAHQAWYTDRLLNAGDFDWGIVGVGLRSGDALRDALAAQDGLYTLVERGPDG 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  86 -WTSRVVGVVKKALHAQVDGlETVLAAMCEPQVAIVSLTITEKGYCHSPATGQLMLDHPFIVADLQNPHQPKSAPGVVVE 164
Cdd:COG0246   92 vEEARVIGSISEVLVAPEDP-EAVLALLADPALRIVSLTITEKGYCLDPATGELDLDHPDIQADLANPAPPRSAPGKLTA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 165 ALARRKAAGLPAFSVMSCDNMPENGHVMRNVTCAYARAVDGELADWIESHVTFPSTMVDRIVPAVTPDTLDKIEQLTGVR 244
Cdd:COG0246  171 ALYRRRAAGLKPFTVLSCDNLPHNGDVLREAVLAFARLWDPELADWIEENVTFPNTMVDRIVPATTDEDRARLAAELGYE 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 245 DPAAVACEPFRQWVIEDNFVAGRPAWEKAGAELVSDVIPFEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDENYRVAA 324
Cdd:COG0246  251 DAAPVVAEPFRQWVIEDDFPAGRPPLEKAGVQFVDDVAPYEEMKLRLLNGSHTALAYLGYLAGYETVAEAMADPLLRAFV 330
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 325 HALMLNEQAPTLK-VKGVDLGRYADLLIARYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLVHQKPFPLLALGVAGWM 403
Cdd:COG0246  331 RRLMLEEIIPTLPpPPGVDLEAYADAVLERFANPAIRHTLARIALDGSQKLPQRLLPTLRDYLAAGRDPKRLALAVAAWL 410
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 404 RYVGGVDEQGNAIDVSDPQLAVIQAAVKGSAEGESRVRALLGIEAIFGKELPREAVFVDAVMKAYQTLLQKGAKATVAQY 483
Cdd:COG0246  411 RYLRGVDDDGEPIELSDPLADELAALAAAADDPADLVRAFLALEAIFGDDLADDPGFVEAVTAALEELLAKGARATLAAL 490

                 ..
gi 556300062 484 VS 485
Cdd:COG0246  491 LA 492
PRK15037 PRK15037
D-mannonate oxidoreductase; Provisional
2-481 0e+00

D-mannonate oxidoreductase; Provisional


Pssm-ID: 184997 [Multi-domain]  Cd Length: 486  Bit Score: 639.00  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062   2 ENTLLQANATL--PQYDRDSLKARIVHLGFGAFHRAHQAVYADILAAEHGSDWGYCEVNLIGGEQQ--IADLNAQDNLYT 77
Cdd:PRK15037   1 MTTIVDSNLPVarPSWDHSRLESRIVHLGCGAFHRAHQALYTHHLLESTDSDWGICEVNLMPGNDRvlIENLKKQQLLYT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  78 VAEMSADAWTSRVVGVVKKALHAQVDGLETVLAAMCEPQVAIVSLTITEKGYCHSPATGQLMLDHPFIVADLQNPHQPKS 157
Cdd:PRK15037  81 VAEKGAESTELKIIGSMKEALHPEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 158 APGVVVEALARRKAAGLPAFSVMSCDNMPENGHVMRNVTCAYARAVDGELADWIESHVTFPSTMVDRIVPAVTPDTLDKI 237
Cdd:PRK15037 161 AIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENVTFPCTMVDRIVPAATPETLQEI 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 238 EQLTGVRDPAAVACEPFRQWVIEDNFVAGRPAWEKAGAELVSDVIPFEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMED 317
Cdd:PRK15037 241 ADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKVGAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTMTN 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 318 ENYRVAAHALMLNEQAPTLKV-KGVDLGRYADLLIARYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLVHQKPFPLLA 396
Cdd:PRK15037 321 PAYRKAAFALMMQEQAPTLSMpEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQNGGSWRHLA 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 397 LGVAGWMRYVGGVDEQGNAIDVSDPQLAVIQaAVKGSAEGESRVRALLGIEAIFGKELPREAVFVDAVMKAYQTLLQKGA 476
Cdd:PRK15037 401 LGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQ-KINAQYQGADRVKALLGLSGIFADDLPQNADFVGAVTAAYQQLCERGA 479

                 ....*
gi 556300062 477 KATVA 481
Cdd:PRK15037 480 RECVA 484
Mannitol_dh_C pfam08125
Mannitol dehydrogenase C-terminal domain;
214-455 5.56e-125

Mannitol dehydrogenase C-terminal domain;


Pssm-ID: 369700  Cd Length: 246  Bit Score: 364.01  E-value: 5.56e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  214 HVTFPSTMVDRIVPAVTPDTLDKIEQLTGVRDPAAVACEPFRQWVIEDNFVAGRPAWEKAGAELVSDVIPFEEMKLRMLN 293
Cdd:pfam08125   2 NVGFPNTMVDRIVPATTDDELAKIAQALGVEDPLPVTVEPFRQWVIEDNFVKGRPLLEKVGVEYVEDVDPYEERKLRILN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  294 GSHSFLAYLGYLAGYQHINDCMEDENYRVAAHALMLNEQAPTL-KVKGVDLGRYADLLIARYSNPALRHRTWQIAMDGSQ 372
Cdd:pfam08125  82 GGHATLAYLGYLAGYQTIHEAMLDPEIRAFVKGVMTEEVAPLLaKVPGDDLEAYADKIIERFSNPYIKDTVWRVARDGSQ 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  373 KLPQRMLDSVRWHLVHQKPFPLLALGVAGWMRYVGGVDEQGNAIDVSDPQLAVIQAAVKGSAEgesRVRALLGIEAIFGK 452
Cdd:pfam08125 162 KLPQRKLPSLRRHIRAGPLPELLALGVAGWMRYLQGVDEGGNYIDPEDPQAQELQAAAIIAKE---RPAAVLAEVSGLGD 238

                  ...
gi 556300062  453 ELP 455
Cdd:pfam08125 239 DLA 241
 
Name Accession Description Interval E-value
MtlD COG0246
Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism];
6-485 0e+00

Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism];


Pssm-ID: 440016 [Multi-domain]  Cd Length: 492  Bit Score: 736.96  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062   6 LQANATLPQYDRDSLKARIVHLGFGAFHRAHQAVYADILAAEHGSDWGYCEVNLIGGEQQIADLNAQDNLYTVAEMSADA 85
Cdd:COG0246   12 LPAGVARPAYDRSALPPGIVHFGVGNFHRAHQAWYTDRLLNAGDFDWGIVGVGLRSGDALRDALAAQDGLYTLVERGPDG 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  86 -WTSRVVGVVKKALHAQVDGlETVLAAMCEPQVAIVSLTITEKGYCHSPATGQLMLDHPFIVADLQNPHQPKSAPGVVVE 164
Cdd:COG0246   92 vEEARVIGSISEVLVAPEDP-EAVLALLADPALRIVSLTITEKGYCLDPATGELDLDHPDIQADLANPAPPRSAPGKLTA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 165 ALARRKAAGLPAFSVMSCDNMPENGHVMRNVTCAYARAVDGELADWIESHVTFPSTMVDRIVPAVTPDTLDKIEQLTGVR 244
Cdd:COG0246  171 ALYRRRAAGLKPFTVLSCDNLPHNGDVLREAVLAFARLWDPELADWIEENVTFPNTMVDRIVPATTDEDRARLAAELGYE 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 245 DPAAVACEPFRQWVIEDNFVAGRPAWEKAGAELVSDVIPFEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDENYRVAA 324
Cdd:COG0246  251 DAAPVVAEPFRQWVIEDDFPAGRPPLEKAGVQFVDDVAPYEEMKLRLLNGSHTALAYLGYLAGYETVAEAMADPLLRAFV 330
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 325 HALMLNEQAPTLK-VKGVDLGRYADLLIARYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLVHQKPFPLLALGVAGWM 403
Cdd:COG0246  331 RRLMLEEIIPTLPpPPGVDLEAYADAVLERFANPAIRHTLARIALDGSQKLPQRLLPTLRDYLAAGRDPKRLALAVAAWL 410
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 404 RYVGGVDEQGNAIDVSDPQLAVIQAAVKGSAEGESRVRALLGIEAIFGKELPREAVFVDAVMKAYQTLLQKGAKATVAQY 483
Cdd:COG0246  411 RYLRGVDDDGEPIELSDPLADELAALAAAADDPADLVRAFLALEAIFGDDLADDPGFVEAVTAALEELLAKGARATLAAL 490

                 ..
gi 556300062 484 VS 485
Cdd:COG0246  491 LA 492
PRK15037 PRK15037
D-mannonate oxidoreductase; Provisional
2-481 0e+00

D-mannonate oxidoreductase; Provisional


Pssm-ID: 184997 [Multi-domain]  Cd Length: 486  Bit Score: 639.00  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062   2 ENTLLQANATL--PQYDRDSLKARIVHLGFGAFHRAHQAVYADILAAEHGSDWGYCEVNLIGGEQQ--IADLNAQDNLYT 77
Cdd:PRK15037   1 MTTIVDSNLPVarPSWDHSRLESRIVHLGCGAFHRAHQALYTHHLLESTDSDWGICEVNLMPGNDRvlIENLKKQQLLYT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  78 VAEMSADAWTSRVVGVVKKALHAQVDGLETVLAAMCEPQVAIVSLTITEKGYCHSPATGQLMLDHPFIVADLQNPHQPKS 157
Cdd:PRK15037  81 VAEKGAESTELKIIGSMKEALHPEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 158 APGVVVEALARRKAAGLPAFSVMSCDNMPENGHVMRNVTCAYARAVDGELADWIESHVTFPSTMVDRIVPAVTPDTLDKI 237
Cdd:PRK15037 161 AIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENVTFPCTMVDRIVPAATPETLQEI 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 238 EQLTGVRDPAAVACEPFRQWVIEDNFVAGRPAWEKAGAELVSDVIPFEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMED 317
Cdd:PRK15037 241 ADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKVGAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTMTN 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 318 ENYRVAAHALMLNEQAPTLKV-KGVDLGRYADLLIARYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLVHQKPFPLLA 396
Cdd:PRK15037 321 PAYRKAAFALMMQEQAPTLSMpEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQNGGSWRHLA 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 397 LGVAGWMRYVGGVDEQGNAIDVSDPQLAVIQaAVKGSAEGESRVRALLGIEAIFGKELPREAVFVDAVMKAYQTLLQKGA 476
Cdd:PRK15037 401 LGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQ-KINAQYQGADRVKALLGLSGIFADDLPQNADFVGAVTAAYQQLCERGA 479

                 ....*
gi 556300062 477 KATVA 481
Cdd:PRK15037 480 RECVA 484
Mannitol_dh_C pfam08125
Mannitol dehydrogenase C-terminal domain;
214-455 5.56e-125

Mannitol dehydrogenase C-terminal domain;


Pssm-ID: 369700  Cd Length: 246  Bit Score: 364.01  E-value: 5.56e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  214 HVTFPSTMVDRIVPAVTPDTLDKIEQLTGVRDPAAVACEPFRQWVIEDNFVAGRPAWEKAGAELVSDVIPFEEMKLRMLN 293
Cdd:pfam08125   2 NVGFPNTMVDRIVPATTDDELAKIAQALGVEDPLPVTVEPFRQWVIEDNFVKGRPLLEKVGVEYVEDVDPYEERKLRILN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  294 GSHSFLAYLGYLAGYQHINDCMEDENYRVAAHALMLNEQAPTL-KVKGVDLGRYADLLIARYSNPALRHRTWQIAMDGSQ 372
Cdd:pfam08125  82 GGHATLAYLGYLAGYQTIHEAMLDPEIRAFVKGVMTEEVAPLLaKVPGDDLEAYADKIIERFSNPYIKDTVWRVARDGSQ 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  373 KLPQRMLDSVRWHLVHQKPFPLLALGVAGWMRYVGGVDEQGNAIDVSDPQLAVIQAAVKGSAEgesRVRALLGIEAIFGK 452
Cdd:pfam08125 162 KLPQRKLPSLRRHIRAGPLPELLALGVAGWMRYLQGVDEGGNYIDPEDPQAQELQAAAIIAKE---RPAAVLAEVSGLGD 238

                  ...
gi 556300062  453 ELP 455
Cdd:pfam08125 239 DLA 241
Mannitol_dh pfam01232
Mannitol dehydrogenase Rossmann domain;
23-185 1.58e-57

Mannitol dehydrogenase Rossmann domain;


Pssm-ID: 395986 [Multi-domain]  Cd Length: 151  Bit Score: 187.61  E-value: 1.58e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062   23 RIVHLGFGAFHRAHQAvYADILAAEHGSDWGYCEVNLIGGEQqIADLNAQDNLYTVAEMSADAWTSRVVGVVKKALHAQv 102
Cdd:pfam01232   2 RIVHFGAGNFHRAHQA-FIGDLLAENGFDWGIVDVNLRVVDA-REALNAQDGLYTVIEDGEEGRQARLVGSVNAVNSVE- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  103 DGLETVLAAMCEPQVAIVSLTITEKGYCHspaTGQLMLDHPFIVADLQNPHqpksapgVVVEALARRKAAGLPAFSVMSC 182
Cdd:pfam01232  79 EDLEALIELMAEPQADIVSTTVTEGGIDA---TGQLDNDLPDIAADLAKPE-------YLVEALKRRRAAGLKPLTIIAC 148

                  ...
gi 556300062  183 DNM 185
Cdd:pfam01232 149 DNM 151
PRK03643 PRK03643
tagaturonate reductase;
69-473 3.48e-48

tagaturonate reductase;


Pssm-ID: 235147 [Multi-domain]  Cd Length: 471  Bit Score: 172.34  E-value: 3.48e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062  69 LNAQDNLYTVA--------EMSadawTSRVVGVVKKALHAQVDgLETVLAAMCEPQVA-IVSLTiTEKGYCHSPatGQLM 139
Cdd:PRK03643  62 LNEQDGLYTLIirglnegeAVS----EARLIRSISREINPYSD-WDEFLKLARNPELRfVFSNT-TEAGISYHA--EDKF 133
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 140 LDHPfivadlqnphqPKSAPGVVVEALARR-------KAAGLpafSVMSCDNMPENGHVMRNVTCAYAR--AVDGELADW 210
Cdd:PRK03643 134 DDAP-----------PVSFPAKLTALLYERfkhfngaADKGL---IIIPCELIDYNGEKLKEIVLRYAQewNLPEAFIQW 199
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 211 IESHVTFPSTMVDRIVPAVTPDTLDKIEQLTGVRDPAAVACEPFRQWVIE-DNFVAGRPAWEKAG--AELVSDVIPFEEM 287
Cdd:PRK03643 200 LEEANTFCSTLVDRIVTGYPRDEAAALEEELGYEDGLLDTAEPFYLWVIEgPKSLAKELPFDKAGlnVLIVDDIKPYRER 279
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 288 KLRMLNGSHSFLAYLGYLAGYQHINDCMEDENYRVAAHALMLNEQAPTLKVKGVDLGRYADLLIARYSNPALRHRTWQIA 367
Cdd:PRK03643 280 KVRILNGAHTALVPVAYLAGLDTVGEAMEDAEIGAFVEKAIYEEIIPVLDLPEDELESFAEAVLDRFRNPFIKHQLLSIA 359
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 368 MDGSQKLPQRMLDSVrwhLVHQKPF----PLLALGVAGWMR-YVGGVDEQGNAIDVSDPQLAVIQAAVKGSAEGESR--- 439
Cdd:PRK03643 360 LNSMSKFRTRILPQL---LAYQERKgtlpARLTFALAALIAfYRGERNGETYPIQDDAHWLERFKQLWSQVDDGEISlae 436
                        410       420       430
                 ....*....|....*....|....*....|....*
gi 556300062 440 -VRALLGIEAIFGKELPREAVFVDAVMKAYQTLLQ 473
Cdd:PRK03643 437 lVAAVLSDEKHWGQDLTQVPGLVEQVTEYLQAILE 471
PRK02318 PRK02318
mannitol-1-phosphate 5-dehydrogenase; Provisional
164-359 9.19e-27

mannitol-1-phosphate 5-dehydrogenase; Provisional


Pssm-ID: 235031 [Multi-domain]  Cd Length: 381  Bit Score: 111.45  E-value: 9.19e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 164 EALARRKAAG-LPAFSVMSCDNMpenghvmRNVTCAYARAV----DGELADWIESHVTFPSTMVDRIVPAVTPDtldkie 238
Cdd:PRK02318 102 KGLKKRKAQGnTKPLNIIACENM-------IRGTSFLKKHVlkalSEDEKAWLEEHVGFVDSAVDRIVPAQKNE------ 168
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556300062 239 qltgvrDPAAVACEPFRQWVIEDNFVAGRPAwEKAGAELVSDVIPFEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDE 318
Cdd:PRK02318 169 ------DPLDVTVEPFSEWIVDKTQFKGALP-KIKGMEYVDNLMPFIERKLFTVNTGHATTAYLGYLKGYKTIREAILDP 241
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 556300062 319 NYRVAAHALMlnEQAPTLKVK--GVD---LGRYADLLIARYSNPAL 359
Cdd:PRK02318 242 SIRAVVKGAL--EESGAVLIKkyGFDkeeHAAYIEKILGRFENPYL 285
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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