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Conserved domains on  [gi|556425415|ref|WP_023310342|]
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MULTISPECIES: transaldolase [Enterobacter]

Protein Classification

transaldolase( domain architecture ID 10792423)

transaldolase transfers a C3 ketol fragment from a ketose donor to an aldose acceptor as part of the non-oxidative branch of the pentose phosphate pathway

EC:  2.2.1.2
Gene Ontology:  GO:0004801

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PRK05269 PRK05269
transaldolase B; Provisional
1-317 0e+00

transaldolase B; Provisional


:

Pssm-ID: 235381 [Multi-domain]  Cd Length: 318  Bit Score: 673.03  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   1 MTDKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVTWAKAQSNDRAQQVVDATDKLAVN 80
Cdd:PRK05269   1 MTNKLEQLKQFTTVVADTGDIEAIKKYQPQDATTNPSLILKAAQIPEYAPLIDDAVAWAKQQSGDRAQQIDDAIDKLAVN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  81 IGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKMYNDAGISNDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFS 160
Cdd:PRK05269  81 FGLEILKLIPGRVSTEVDARLSFDTEATIAKARKLIALYEEAGISKDRILIKIASTWEGIRAAEQLEKEGINCNLTLLFS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 161 FAQARACAEAGVYLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIELAGCD 240
Cdd:PRK05269 161 FAQARACAEAGVFLISPFVGRILDWYKKNTGKKEYAPAEDPGVVSVTKIYNYYKKHGYKTVVMGASFRNTGQILELAGCD 240
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556425415 241 RLTIAPALLKELAESEGTIERKLSYTGEVKARPERITESEFLWQHNQDPMAVDKLADGIRKFAVDQGKLEKMIGDLL 317
Cdd:PRK05269 241 RLTISPALLEELAASEGELERKLSPPGEAKARPVPLTEAEFRWQHNEDAMATEKLAEGIRKFAKDQEKLEKLIAAKL 317
 
Name Accession Description Interval E-value
PRK05269 PRK05269
transaldolase B; Provisional
1-317 0e+00

transaldolase B; Provisional


Pssm-ID: 235381 [Multi-domain]  Cd Length: 318  Bit Score: 673.03  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   1 MTDKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVTWAKAQSNDRAQQVVDATDKLAVN 80
Cdd:PRK05269   1 MTNKLEQLKQFTTVVADTGDIEAIKKYQPQDATTNPSLILKAAQIPEYAPLIDDAVAWAKQQSGDRAQQIDDAIDKLAVN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  81 IGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKMYNDAGISNDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFS 160
Cdd:PRK05269  81 FGLEILKLIPGRVSTEVDARLSFDTEATIAKARKLIALYEEAGISKDRILIKIASTWEGIRAAEQLEKEGINCNLTLLFS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 161 FAQARACAEAGVYLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIELAGCD 240
Cdd:PRK05269 161 FAQARACAEAGVFLISPFVGRILDWYKKNTGKKEYAPAEDPGVVSVTKIYNYYKKHGYKTVVMGASFRNTGQILELAGCD 240
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556425415 241 RLTIAPALLKELAESEGTIERKLSYTGEVKARPERITESEFLWQHNQDPMAVDKLADGIRKFAVDQGKLEKMIGDLL 317
Cdd:PRK05269 241 RLTISPALLEELAASEGELERKLSPPGEAKARPVPLTEAEFRWQHNEDAMATEKLAEGIRKFAKDQEKLEKLIAAKL 317
talAB TIGR00874
transaldolase; This family includes the majority of known and predicted transaldolase ...
3-317 0e+00

transaldolase; This family includes the majority of known and predicted transaldolase sequences, including E. coli TalA and TalB. It excluded two other families. The first includes E. coli transaldolase-like protein TalC. The second family includes the putative transaldolases of Helicobacter pylori and Mycobacterium tuberculosis. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 162081  Cd Length: 317  Bit Score: 580.57  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415    3 DKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVTWAKAQSNDRAQQVVDATDKLAVNIG 82
Cdd:TIGR00874   1 NQLDQLKQFTVVVADTGDIEAIKKYQPQDATTNPSLILAAAQLPKYAELIDEAVAWGKKQGKDDAQQVENALDKLAVNFG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   83 LEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKMYNDAGISNDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFA 162
Cdd:TIGR00874  81 LEILKIVPGRVSTEVDARLSFDTEATVEKARHLIKLYEDAGVDKKRILIKIASTWEGIRAAEELEKEGIHCNLTLLFSFV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  163 QARACAEAGVYLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIELAGCDRL 242
Cdd:TIGR00874 161 QAIACAEAKVTLISPFVGRILDWYKAATGKKEYSIEEDPGVASVKKIYNYYKKHGYPTEVMGASFRNKEEILALAGCDRL 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556425415  243 TIAPALLKELAESEGTIERKLSYTGE--VKARPERITESEFLWQHNQDPMAVDKLADGIRKFAVDQGKLEKMIGDLL 317
Cdd:TIGR00874 241 TISPALLDELKESTGPVERKLDPESAkkVDKQPIILDESEFRFLHNEDAMATEKLAEGIRKFAADQEKLEKLLEEKL 317
Transaldolase_TalAB cd00957
Transaldolases including both TalA and TalB; Transaldolases including both TalA and TalB. The ...
4-313 0e+00

Transaldolases including both TalA and TalB; Transaldolases including both TalA and TalB. The enzyme catalyses the reversible transfer of a dyhydroxyacetone moiety, derived from fructose-6-phosphate to erythrose-4-phosphate yielding sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate. The catalytic mechanism is similar to other class I aldolases. The enzyme is found in the non-oxidative branch of the pentose phosphate pathway and forms a dimer in solution.


Pssm-ID: 188644 [Multi-domain]  Cd Length: 313  Bit Score: 537.97  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   4 KLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVTWAKAQSNDRAQQVVDATDKLAVNIGL 83
Cdd:cd00957    2 QLDQLKKFTTIVADTGDFEAIKKFKPQDATTNPSLILAAAKLPEYNKLVDEAIAYAKKKGGSDEDQISNALDKLLVNFGT 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  84 EILKLVPGRISTEVDARLSYDTEASIAKAKRLIKMYNDAGISNDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFAQ 163
Cdd:cd00957   82 EILKLIPGRVSTEVDARLSFDTNATIAKARKLIKLYEEAGIDKERILIKIAATWEGIQAAKQLEKEGIHCNLTLLFSFAQ 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 164 ARACAEAGVYLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIELAGCDRLT 243
Cdd:cd00957  162 AVACAEAGVTLISPFVGRILDWYKKHSGDKAYTAEEDPGVASVKKIYNYYKKFGYKTKVMGASFRNIGQILALAGCDYLT 241
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556425415 244 IAPALLKELAESEGTIERKLSY--TGEVKARPERITESEFLWQHNQDPMAVDKLADGIRKFAVDQGKLEKMI 313
Cdd:cd00957  242 ISPALLEELKNSTAKVERKLDPaaSKALDIHPNFLDESAFRWALNEDAMAVEKLSEGIRGFAKDAVKLEKLI 313
TAL_FSA pfam00923
Transaldolase/Fructose-6-phosphate aldolase; Transaldolase (TAL) is an enzyme of the pentose ...
14-257 2.56e-96

Transaldolase/Fructose-6-phosphate aldolase; Transaldolase (TAL) is an enzyme of the pentose phosphate pathway (PPP) found almost ubiquitously in the three domains of life (Archaea, Bacteria, and Eukarya). TAL shares a high degree of structural similarity and sequence identity with fructose-6-phosphate aldolase (FSA). They both belong to the class I aldolase family. Their protein structures have been revealed.


Pssm-ID: 395737 [Multi-domain]  Cd Length: 226  Bit Score: 284.05  E-value: 2.56e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   14 VVADTGDIAAMKLYQP----QDATTNPSLILNAAqipEYRKLIDDAVtwakaqsndraqqvvdatdklavnigLEILKLV 89
Cdd:pfam00923   1 IWLDTADRDLIKKLIEeggiDGVTTNPSIFLKAI---EYSALYDEAI--------------------------AEIKEIG 51
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   90 PGRISTEVDARLSYDTEASIAKAKRLIKMYNDagisnDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFAQARACAE 169
Cdd:pfam00923  52 DGPVSLEVDPRLADDTEGTIEEARRLIALYGR-----PNVLIKIPATWEGIKAIKELSAEGINVNVTLIFSLAQALAAAE 126
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  170 AGVYLISPFVGRILDWYKANTDKkeyAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIELAGCDRLTIAPALL 249
Cdd:pfam00923 127 AGASVISPFVGRIDDWGDKRLGA---ALRGDDGIANAKEIYQIYKKYGWSTGVLAASFRNVLYVLALAGCDTITIPPDTL 203

                  ....*...
gi 556425415  250 KELAESEG 257
Cdd:pfam00923 204 EALAKDEG 211
TalA COG0176
Transaldolase/fructose-6-phosphate aldolase [Carbohydrate transport and metabolism]; ...
12-260 4.84e-77

Transaldolase/fructose-6-phosphate aldolase [Carbohydrate transport and metabolism]; Transaldolase/fructose-6-phosphate aldolase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 439946 [Multi-domain]  Cd Length: 214  Bit Score: 234.58  E-value: 4.84e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  12 TTVVADTGDIAAMK----LYQPQDATTNPSLILNAAqipeyrkliddavtwakaqsndraqqvvdatDKLAVNIGLEILK 87
Cdd:COG0176    1 MKLWLDTADREEIKelidLGGVDGVTTNPSLIAKAG-------------------------------IKDFVEDIREICD 49
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  88 LVPGRISTEVdarLSYDTEASIAKAKRLIKMYNDagisndRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFAQARAC 167
Cdd:COG0176   50 IVDGPVSAEV---LATDTEGMIAEARRLAALYRP------NVVIKIPATEEGLKAIEELSAEGIKVNVTLIFSAAQALLA 120
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 168 AEAGVYLISPFVGRILDWykantdkkeyapAEDpGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIE--LAGCDRLTIA 245
Cdd:COG0176  121 AEAGASYVSPFVGRIDDI------------GID-GIALVREIYQIYKNYGARTRILAASFRNPLQVLEaaLAGADTVTIP 187
                        250
                 ....*....|....*
gi 556425415 246 PALLKELAESEGTIE 260
Cdd:COG0176  188 PAVLEALADHPLTDE 202
 
Name Accession Description Interval E-value
PRK05269 PRK05269
transaldolase B; Provisional
1-317 0e+00

transaldolase B; Provisional


Pssm-ID: 235381 [Multi-domain]  Cd Length: 318  Bit Score: 673.03  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   1 MTDKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVTWAKAQSNDRAQQVVDATDKLAVN 80
Cdd:PRK05269   1 MTNKLEQLKQFTTVVADTGDIEAIKKYQPQDATTNPSLILKAAQIPEYAPLIDDAVAWAKQQSGDRAQQIDDAIDKLAVN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  81 IGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKMYNDAGISNDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFS 160
Cdd:PRK05269  81 FGLEILKLIPGRVSTEVDARLSFDTEATIAKARKLIALYEEAGISKDRILIKIASTWEGIRAAEQLEKEGINCNLTLLFS 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 161 FAQARACAEAGVYLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIELAGCD 240
Cdd:PRK05269 161 FAQARACAEAGVFLISPFVGRILDWYKKNTGKKEYAPAEDPGVVSVTKIYNYYKKHGYKTVVMGASFRNTGQILELAGCD 240
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556425415 241 RLTIAPALLKELAESEGTIERKLSYTGEVKARPERITESEFLWQHNQDPMAVDKLADGIRKFAVDQGKLEKMIGDLL 317
Cdd:PRK05269 241 RLTISPALLEELAASEGELERKLSPPGEAKARPVPLTEAEFRWQHNEDAMATEKLAEGIRKFAKDQEKLEKLIAAKL 317
talAB TIGR00874
transaldolase; This family includes the majority of known and predicted transaldolase ...
3-317 0e+00

transaldolase; This family includes the majority of known and predicted transaldolase sequences, including E. coli TalA and TalB. It excluded two other families. The first includes E. coli transaldolase-like protein TalC. The second family includes the putative transaldolases of Helicobacter pylori and Mycobacterium tuberculosis. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 162081  Cd Length: 317  Bit Score: 580.57  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415    3 DKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVTWAKAQSNDRAQQVVDATDKLAVNIG 82
Cdd:TIGR00874   1 NQLDQLKQFTVVVADTGDIEAIKKYQPQDATTNPSLILAAAQLPKYAELIDEAVAWGKKQGKDDAQQVENALDKLAVNFG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   83 LEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKMYNDAGISNDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFA 162
Cdd:TIGR00874  81 LEILKIVPGRVSTEVDARLSFDTEATVEKARHLIKLYEDAGVDKKRILIKIASTWEGIRAAEELEKEGIHCNLTLLFSFV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  163 QARACAEAGVYLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIELAGCDRL 242
Cdd:TIGR00874 161 QAIACAEAKVTLISPFVGRILDWYKAATGKKEYSIEEDPGVASVKKIYNYYKKHGYPTEVMGASFRNKEEILALAGCDRL 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556425415  243 TIAPALLKELAESEGTIERKLSYTGE--VKARPERITESEFLWQHNQDPMAVDKLADGIRKFAVDQGKLEKMIGDLL 317
Cdd:TIGR00874 241 TISPALLDELKESTGPVERKLDPESAkkVDKQPIILDESEFRFLHNEDAMATEKLAEGIRKFAADQEKLEKLLEEKL 317
PRK12346 PRK12346
transaldolase A; Provisional
2-317 0e+00

transaldolase A; Provisional


Pssm-ID: 183458  Cd Length: 316  Bit Score: 563.57  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   2 TDKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVTWAKAQSNDRAQQVVDATDKLAVNI 81
Cdd:PRK12346   1 MNQLDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLPQYQHLIDDAIAWGKKQGGTQEQQVVAACDKLAVNF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  82 GLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKMYNDAGISNDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSF 161
Cdd:PRK12346  81 GAEILKSVPGRVSTEVDARLSFDREKSIEKARHLVDLYQQQGIDKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 162 AQARACAEAGVYLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIELAGCDR 241
Cdd:PRK12346 161 AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHRYETIVMGASFRRTEQILALAGCDR 240
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556425415 242 LTIAPALLKELAESEGTIERKLSYTGEVKARPERITESEFLWQHNQDPMAVDKLADGIRKFAVDQGKLEKMIGDLL 317
Cdd:PRK12346 241 LTISPNLLKELQESESPVERKLIPSSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL 316
Transaldolase_TalAB cd00957
Transaldolases including both TalA and TalB; Transaldolases including both TalA and TalB. The ...
4-313 0e+00

Transaldolases including both TalA and TalB; Transaldolases including both TalA and TalB. The enzyme catalyses the reversible transfer of a dyhydroxyacetone moiety, derived from fructose-6-phosphate to erythrose-4-phosphate yielding sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate. The catalytic mechanism is similar to other class I aldolases. The enzyme is found in the non-oxidative branch of the pentose phosphate pathway and forms a dimer in solution.


Pssm-ID: 188644 [Multi-domain]  Cd Length: 313  Bit Score: 537.97  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   4 KLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVTWAKAQSNDRAQQVVDATDKLAVNIGL 83
Cdd:cd00957    2 QLDQLKKFTTIVADTGDFEAIKKFKPQDATTNPSLILAAAKLPEYNKLVDEAIAYAKKKGGSDEDQISNALDKLLVNFGT 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  84 EILKLVPGRISTEVDARLSYDTEASIAKAKRLIKMYNDAGISNDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFAQ 163
Cdd:cd00957   82 EILKLIPGRVSTEVDARLSFDTNATIAKARKLIKLYEEAGIDKERILIKIAATWEGIQAAKQLEKEGIHCNLTLLFSFAQ 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 164 ARACAEAGVYLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIELAGCDRLT 243
Cdd:cd00957  162 AVACAEAGVTLISPFVGRILDWYKKHSGDKAYTAEEDPGVASVKKIYNYYKKFGYKTKVMGASFRNIGQILALAGCDYLT 241
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556425415 244 IAPALLKELAESEGTIERKLSY--TGEVKARPERITESEFLWQHNQDPMAVDKLADGIRKFAVDQGKLEKMI 313
Cdd:cd00957  242 ISPALLEELKNSTAKVERKLDPaaSKALDIHPNFLDESAFRWALNEDAMAVEKLSEGIRGFAKDAVKLEKLI 313
PTZ00411 PTZ00411
transaldolase-like protein; Provisional
1-317 0e+00

transaldolase-like protein; Provisional


Pssm-ID: 240406  Cd Length: 333  Bit Score: 505.81  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   1 MTDKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVTWAKAQS----------NDRAQQV 70
Cdd:PTZ00411   1 MPNQLEALKEHTTVVADTGDFSLLKKFQPEDATTNPSLVLAAAQMPEYAHLIDDAIKYAKANVsrlrdpllsdEEKEELV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  71 VDATDKLAVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKMYNDAGISNDRILIKLASTWQGIRAAEQLEKDG 150
Cdd:PTZ00411  81 ELVVDKLTVNFGVEILKIVPGRVSTEVDARLSFDKQAMVDKARKIIKMYEEAGISKDRILIKLASTWEGIQAAKALEKEG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 151 INCNLTLLFSFAQARACAEAGVYLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNV 230
Cdd:PTZ00411 161 IHCNLTLLFSFAQAVACAQAGVTLISPFVGRILDWYKKPEKAESYVGAQDPGVISVTKIYNYYKKHGYKTIVMGASFRNT 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 231 GEIIELAGCDRLTIAPALLKELAESEGT-IERKLSYTGEVKARPERI--TESEFLWQHNQDPMAVDKLADGIRKFAVDQG 307
Cdd:PTZ00411 241 GEILELAGCDKLTISPKLLEELANTEDGpVERKLDPEKLTEDTEKLPelTEKEFRWELNEDAMATEKLAEGIRNFAKDLE 320
                        330
                 ....*....|
gi 556425415 308 KLEKMIGDLL 317
Cdd:PTZ00411 321 KLENVIRAKL 330
PRK12309 PRK12309
transaldolase;
1-317 1.42e-169

transaldolase;


Pssm-ID: 183426 [Multi-domain]  Cd Length: 391  Bit Score: 476.15  E-value: 1.42e-169
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   1 MTDKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVTWAKAQSNDRA--QQVV-DATDKL 77
Cdd:PRK12309   2 MASLLEQLRQMTVVVADTGDIQAIEKFTPRDATTNPSLITAAAQMPQYQSIVDETLRQARKELGSDApvEDVVaLAFDRL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  78 AVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKMYNDAGISNDRILIKLASTWQGIRAAEQLEKDGINCNLTL 157
Cdd:PRK12309  82 AVAFGLKILKIVPGRVSTEVDARLSYDTEATIAKARKLISLYEDAGISRDRVLIKIASTWEGIKAAEVLEKEGIHCNLTL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 158 LFSFAQARACAEAGVYLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIELA 237
Cdd:PRK12309 162 LFGFHQAIACAEAGVTLISPFVGRILDWYKKETGRDSYPGAEDPGVQSVTQIYNYYKKFGYKTEVMGASFRNIGEIIELA 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 238 GCDRLTIAPALLKELAESEGTIERKLSYTGEVKARPERIT--ESEFLWQHNQDPMAVDKLADGIRKFAVDQGKLEKMIGD 315
Cdd:PRK12309 242 GCDLLTISPKLLEQLRSTEAELPRKLDPANAAGMEIEKIHmdRATFDKMHAEDRMASEKLDEGIKGFSKALETLEKLLAH 321

                 ..
gi 556425415 316 LL 317
Cdd:PRK12309 322 RL 323
TAL_FSA pfam00923
Transaldolase/Fructose-6-phosphate aldolase; Transaldolase (TAL) is an enzyme of the pentose ...
14-257 2.56e-96

Transaldolase/Fructose-6-phosphate aldolase; Transaldolase (TAL) is an enzyme of the pentose phosphate pathway (PPP) found almost ubiquitously in the three domains of life (Archaea, Bacteria, and Eukarya). TAL shares a high degree of structural similarity and sequence identity with fructose-6-phosphate aldolase (FSA). They both belong to the class I aldolase family. Their protein structures have been revealed.


Pssm-ID: 395737 [Multi-domain]  Cd Length: 226  Bit Score: 284.05  E-value: 2.56e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   14 VVADTGDIAAMKLYQP----QDATTNPSLILNAAqipEYRKLIDDAVtwakaqsndraqqvvdatdklavnigLEILKLV 89
Cdd:pfam00923   1 IWLDTADRDLIKKLIEeggiDGVTTNPSIFLKAI---EYSALYDEAI--------------------------AEIKEIG 51
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415   90 PGRISTEVDARLSYDTEASIAKAKRLIKMYNDagisnDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFAQARACAE 169
Cdd:pfam00923  52 DGPVSLEVDPRLADDTEGTIEEARRLIALYGR-----PNVLIKIPATWEGIKAIKELSAEGINVNVTLIFSLAQALAAAE 126
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  170 AGVYLISPFVGRILDWYKANTDKkeyAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIELAGCDRLTIAPALL 249
Cdd:pfam00923 127 AGASVISPFVGRIDDWGDKRLGA---ALRGDDGIANAKEIYQIYKKYGWSTGVLAASFRNVLYVLALAGCDTITIPPDTL 203

                  ....*...
gi 556425415  250 KELAESEG 257
Cdd:pfam00923 204 EALAKDEG 211
Transaldolase cd00439
Transaldolase; Transaldolase. Enzymes found in the non-oxidative branch of the pentose ...
13-253 3.22e-77

Transaldolase; Transaldolase. Enzymes found in the non-oxidative branch of the pentose phosphate pathway, that catalyze the reversible transfer of a dihydroxyacetone group from fructose-6-phosphate to erythrose-4-phosphate yielding sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate. They are members of the class I aldolases, who are characterized by using a Schiff-base mechanism for stabilization of the reaction intermediates.


Pssm-ID: 188631 [Multi-domain]  Cd Length: 252  Bit Score: 236.48  E-value: 3.22e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  13 TVVADTGDIAAMKLYQ----PQDATTNPSLILNAAQIPEYRKLIDDAVTWAKAQSNDRAQQVVDATDKLAVNIGLEILKL 88
Cdd:cd00439    1 SPWYDTLDRPATDLLPlirgVRGVTTNPSIIQAAISTSNAYNDQFRTLVESGKDIESAYWELVVKDIQDACKLFEPIYDQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  89 V--PGRISTEVDARLSYDTEASIAKAKRLIKMYNDagisnDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFAQARA 166
Cdd:cd00439   81 TeaDGRVSVEVSARLADDTQGMVEAAKYLSKVVNR-----RNIYIKIPATAEGIPAIKDLIAAGISVNVTLIFSIAQYEA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 167 CAEAGVYLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIELAGCDRLTIAP 246
Cdd:cd00439  156 VADAGTSVASPFVSRIDTLMDKMLEQIGLDLRGKAGVAQVTLAYKLYKQKFKKQRVLWASFSDTLYVAPLIGCDTVTTMP 235

                 ....*..
gi 556425415 247 ALLKELA 253
Cdd:cd00439  236 DQALEAG 242
TalA COG0176
Transaldolase/fructose-6-phosphate aldolase [Carbohydrate transport and metabolism]; ...
12-260 4.84e-77

Transaldolase/fructose-6-phosphate aldolase [Carbohydrate transport and metabolism]; Transaldolase/fructose-6-phosphate aldolase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 439946 [Multi-domain]  Cd Length: 214  Bit Score: 234.58  E-value: 4.84e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  12 TTVVADTGDIAAMK----LYQPQDATTNPSLILNAAqipeyrkliddavtwakaqsndraqqvvdatDKLAVNIGLEILK 87
Cdd:COG0176    1 MKLWLDTADREEIKelidLGGVDGVTTNPSLIAKAG-------------------------------IKDFVEDIREICD 49
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  88 LVPGRISTEVdarLSYDTEASIAKAKRLIKMYNDagisndRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFAQARAC 167
Cdd:COG0176   50 IVDGPVSAEV---LATDTEGMIAEARRLAALYRP------NVVIKIPATEEGLKAIEELSAEGIKVNVTLIFSAAQALLA 120
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 168 AEAGVYLISPFVGRILDWykantdkkeyapAEDpGVVSVTEIYEYYKQHGYETVVMGASFRNVGEIIE--LAGCDRLTIA 245
Cdd:COG0176  121 AEAGASYVSPFVGRIDDI------------GID-GIALVREIYQIYKNYGARTRILAASFRNPLQVLEaaLAGADTVTIP 187
                        250
                 ....*....|....*
gi 556425415 246 PALLKELAESEGTIE 260
Cdd:COG0176  188 PAVLEALADHPLTDE 202
Transaldolase_FSA cd00956
Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; ...
17-258 5.57e-32

Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea, which are member of the MipB/TalC subfamily of class I aldolases. FSA catalyze an aldol cleavage of fructose 6-phosphate and do not utilize fructose, fructose 1-phosphate, fructose 1,6-phosphate, or dihydroxyacetone phosphate. The enzymes belong to the transaldolase family that serves in transfer reactions in the pentose phosphate cycle, and are more distantly related to fructose 1,6-bisphosphate aldolase.


Pssm-ID: 188643 [Multi-domain]  Cd Length: 211  Bit Score: 118.45  E-value: 5.57e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  17 DTGDIAAMKLYQPQ----DATTNPSLIlnaaqipeyrkliddavtwAKAQSNDRAQQVvdatdklavnigLEILKLVPGR 92
Cdd:cd00956    5 DTADLEEIKKASETglldGVTTNPSLI-------------------AKSGRIDFEAVL------------KEICEIIDGP 53
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  93 ISTEVDARlsyDTEASIAKAKRLIKMyndagisNDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFAQARACAEAGV 172
Cdd:cd00956   54 VSAQVVST---DAEGMVAEARKLASL-------GGNVVVKIPVTEDGLKAIKKLSEEGIKTNVTAIFSAAQALLAAKAGA 123
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 173 YLISPFVGRIldwykANTdkkeyapAEDPGVVsVTEIYEYYKQHGYETVVMGASFRNVGEIIE--LAGCDRLTIAPALLK 250
Cdd:cd00956  124 TYVSPFVGRI-----DDL-------GGDGMEL-IREIRTIFDNYGFDTKILAASIRNPQHVIEaaLAGADAITLPPDVLE 190

                 ....*...
gi 556425415 251 ELAESEGT 258
Cdd:cd00956  191 QLLKHPLT 198
Transaldolase_like cd00955
Transaldolase-like proteins from plants and bacteria; Transaldolase-like proteins from plants ...
32-216 4.57e-19

Transaldolase-like proteins from plants and bacteria; Transaldolase-like proteins from plants and bacteria. Transaldolase is found in the non-oxidative branch of the pentose phosphate pathway, that catalyze the reversible transfer of a dihydroxyacetone group from fructose-6-phosphate to erythrose-4-phosphate yielding sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate. They are members of the class I aldolases, who are characterized by using a Schiff-base mechanism for stabilization of the reaction intermediates.


Pssm-ID: 188642 [Multi-domain]  Cd Length: 338  Bit Score: 86.22  E-value: 4.57e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  32 ATTNPSLILNA-AQIPEYRKLIDDAVtwAKAQSNDRA------QQVVDATDKLAVNigLEILKLVPGRISTEVDARLSYD 104
Cdd:cd00955   29 VTSNPAIFEKAiAGSAAYDDQIRALK--GQGLDAEAIyealaiEDIQDACDLLAPV--YEQTGGNDGYVSLEVSPRLADD 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415 105 TEASIAKAKRLikmYNDAGISNdrILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFAQARACAEAgvYL---------- 174
Cdd:cd00955  105 TQGTIAEAKRL---WKAVGRPN--LMIKIPATEAGLPAIEELIAAGISVNVTLIFSLEQYEAVAEA--YLrglerrvegg 177
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 556425415 175 ---------ISPFVGRIldwyKANTDKKEYAPAEDP-----GVVSVTEIYEYYKQH 216
Cdd:cd00955  178 gdlsqvasvASFFVSRV----DTLIDKKLDAPEAKAlqgkvAIANAKLAYQEYQEK 229
PRK03903 PRK03903
transaldolase; Provisional
91-226 5.79e-16

transaldolase; Provisional


Pssm-ID: 235171  Cd Length: 274  Bit Score: 76.56  E-value: 5.79e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  91 GRISTEVDARLSYDTEASIAKAKRLIKmyndaGISNDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFAQARACAEA 170
Cdd:PRK03903  43 GFISIEIDPFLEDDAAGSIEEGKRLYK-----TIGRPNVMIKVPATKAGYEAMSALMKKGISVNATLIFSPEQAKECAEA 117
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556425415 171 -------------GVylISPFVGRI---LDwykaNTDKKEYAPAEdPGVVSVTEIYEY-YKQHGYETVVMGAS 226
Cdd:PRK03903 118 lneglkkntkdpkAV--ISVFVSRFdrlLD----PKLAPKNLQAK-SGIMNATKCYNQiEQHANKNIRTLFAS 183
PRK03343 PRK03343
transaldolase; Validated
33-174 4.25e-15

transaldolase; Validated


Pssm-ID: 235117  Cd Length: 368  Bit Score: 74.86  E-value: 4.25e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  33 TTNPSlILNAA---------QIPE-----------YRKLIDDAVTWAKaqsnDRAQQVVDATDKlavnigleilklVPGR 92
Cdd:PRK03343  43 TSNPA-IFQKAiaggdaydaQIAElaaagadveeaYEELTTADVRNAC----DVLRPVYEATGG------------VDGR 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  93 ISTEVDARLSYDTEASIAKAKRLIKMyndagISNDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFAQARACAEAgv 172
Cdd:PRK03343 106 VSIEVSPRLAHDTEATIAEARRLWAA-----VDRPNLMIKIPATPEGLPAIEALIAEGISVNVTLIFSVERYRAVADA-- 178

                 ..
gi 556425415 173 YL 174
Cdd:PRK03343 179 YL 180
PRK09533 PRK09533
bifunctional transaldolase/phosoglucose isomerase; Validated
33-170 4.11e-11

bifunctional transaldolase/phosoglucose isomerase; Validated


Pssm-ID: 236551 [Multi-domain]  Cd Length: 948  Bit Score: 63.84  E-value: 4.11e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556425415  33 TTNPSLILNA-AQIPEYrkliDDAVTWAKAQsNDRAqqVVDATDKLAV-NI--GLEILKLV-------PGRISTEVDARL 101
Cdd:PRK09533  42 TSNPAIFEKAiGSSDEY----DDAIKAALAE-GDRS--VIELYETLAIeDIqaAADVLRPVydatdgaDGFVSLEVSPYL 114
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556425415 102 SYDTEASIAKAKRLIKMYNdagisNDRILIKLASTWQGIRAAEQLEKDGINCNLTLLFSFAQARACAEA 170
Cdd:PRK09533 115 ALDTEGTIAEARRLWAAVD-----RPNLMIKVPATPEGLPAIRQLIAEGINVNVTLLFSQDVYEEVAEA 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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