NCBI Conserved Domain Search

Conserved domains on [gi|556427173|ref|WP_023312095|]

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MULTISPECIES: ABC transporter ATP-binding protein [Enterobacteriaceae]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11484204)

ABC transporter ATP-binding protein similar to DppD and OppD, the ATPase subunits of complexes which are responsible for coupling the energy of ATP hydrolysis to the import of peptides or oligopeptides, respectively

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

oppD

PRK09473

oligopeptide transporter ATP-binding component; Provisional

8-337

0e+00

oligopeptide transporter ATP-binding component; Provisional

Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 784.68 E-value: 0e+00

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   8 TAPQAQQQNNLLLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKFNG 87
Cdd:PRK09473   1 TVPLAQQQADALLDVKDLRVTFSTPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSATFNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  88 REILNLPEHELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPH 167
Cdd:PRK09473  81 REILNLPEKELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEARKRMKMYPH 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 168 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRT 247
Cdd:PRK09473 161 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 248 MEYGKARDVFYQPAHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICNSAPPLEEFAPGRLR 327
Cdd:PRK09473 241 MEYGNARDVFYQPSHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSAPPLEEFGPGRLR 320

                        330
                 ....*....|
gi 556427173 328 ACFKPQEELV 337
Cdd:PRK09473 321 ACFKPVEELL 330

Name

Accession

Description

Interval

E-value

oppD

PRK09473

oligopeptide transporter ATP-binding component; Provisional

8-337

0e+00

oligopeptide transporter ATP-binding component; Provisional

Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 784.68 E-value: 0e+00

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   8 TAPQAQQQNNLLLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKFNG 87
Cdd:PRK09473   1 TVPLAQQQADALLDVKDLRVTFSTPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSATFNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  88 REILNLPEHELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPH 167
Cdd:PRK09473  81 REILNLPEKELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEARKRMKMYPH 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 168 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRT 247
Cdd:PRK09473 161 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 248 MEYGKARDVFYQPAHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICNSAPPLEEFAPGRLR 327
Cdd:PRK09473 241 MEYGNARDVFYQPSHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSAPPLEEFGPGRLR 320

                        330
                 ....*....|
gi 556427173 328 ACFKPQEELV 337
Cdd:PRK09473 321 ACFKPVEELL 330

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

19-335

0e+00

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 556.59 E-value: 0e+00

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKFNGREILNLPEHEL 98
Cdd:COG0444    1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPGITSGEILFDGEDLLKLSEKEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQRVM 178
Cdd:COG0444   81 RKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDPERRLDRYPHELSGGMRQRVM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFY 258
Cdd:COG0444  161 IARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELFE 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 259 QPAHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEIC-NSAPPLEEFAPGRLRACFKPQEE 335
Cdd:COG0444  241 NPRHPYTRALLSSIPRLDPDGRRLIPIPGEPPSLLNPPSGCRFHPRCPYAMDRCrEEEPPLREVGPGHRVACHLYEEE 318

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

19-251

7.32e-125

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 357.20 E-value: 7.32e-125

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAangVIGGSAKFNGREILNLPEhEL 98
Cdd:cd03257    1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLK---PTSGSIIFDGKDLLKLSR-RL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEEsVKMLDAVKMPEARKRMRMFPHEFSGGMRQRVM 178
Cdd:cd03257   77 RKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKE-AVLLLLVGVGLPEEVLNRYPHELSGGQRQRVA 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03257  156 IARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228

nickel_nikD

TIGR02770

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...

38-271

5.20e-78

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 238.42 E-value: 5.20e-78

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   38 AVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVI-GGSAKFNGREILNLpehelnKLRAEQISMIFQDPMTS 116
Cdd:TIGR02770   1 LVQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLTQtSGEILLDGRPLLPL------SIRGRHIATIMQNPRTA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  117 LNPYMRVGEQLMEVLMLHKGLGKaEAFEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPT 196
Cdd:TIGR02770  75 FNPLFTMGNHAIETLRSLGKLSK-QARALILEALEAVGLPDPEEVLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPT 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173  197 TALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPYSIGLLNA 271
Cdd:TIGR02770 154 TDLDVVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLSA 228

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

39-197

3.41e-41

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 140.86 E-value: 3.41e-41

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   39 VNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREILNLPEHELNKlraeQISMIFQDPmtSLN 118
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSP---TEGTILLDGQDLTDDERKSLRK----EIGYVFQDP--QLF 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  119 PYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEARKR-MRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTT 197
Cdd:pfam00005  72 PRLTVRENLRLGLLL-KGLSKREKDARAEEALEKLGLGDLADRpVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

34-233

1.74e-17

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 79.20 E-value: 1.74e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngVIGGSAKFNGREILNLPEHelnklraeqISMIFQDP 113
Cdd:NF040873   3 GGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRP--TSGTVRRAGGARVAYVPQR---------SEVPDSLP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 MTSlnpymrvgEQLMEV-LMLHKGLGK---AEAFEESVKMLDAVKMPEARKRMRmfpHEFSGGMRQRVMIAMALLCRPKL 189
Cdd:NF040873  72 LTV--------RDLVAMgRWARRGLWRrltRDDRAAVDDALERVGLADLAGRQL---GELSGGQRQRALLAQGLAQEADL 140

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 556427173 190 LIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVA 233
Cdd:NF040873 141 LLLDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVR 183

GguA

NF040905

sugar ABC transporter ATP-binding protein;

19-249

6.21e-16

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 78.29 E-value: 6.21e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLA---ANGVIGGSAKFNGREIlnlpe 95
Cdd:NF040905   1 ILEMRGITKTF----PGVKALDDVNLSVREGEIHALCGENGAGKS----TLMKVLSgvyPHGSYEGEILFDGEVC----- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  96 hELNKLRA-EQ--ISMIFQDpmTSLNPYMRVGEQLMevlmlhkgLGK----------AEAFEESVKMLDAVKMPEArkrm 162
Cdd:NF040905  68 -RFKDIRDsEAlgIVIIHQE--LALIPYLSIAENIF--------LGNerakrgvidwNETNRRARELLAKVGLDES---- 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 163 rmfPHEFSG----GMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIImITHDLGVVAGICDK 238
Cdd:NF040905 133 ---PDTLVTdigvGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSII-ISHKLNEIRRVADS 208

                        250
                 ....*....|.
gi 556427173 239 VLVMYAGRTME 249
Cdd:NF040905 209 ITVLRDGRTIE 219

GguA

NF040905

sugar ABC transporter ATP-binding protein;

39-246

6.90e-15

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 75.21 E-value: 6.90e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  39 VNDLNFNLRAGETLGIVGESGSGKSQTAFALMGllAANGV-IGGSAKFNGREI------------------------LNL 93
Cdd:NF040905 276 VDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFG--RSYGRnISGTVFKDGKEVdvstvsdaidaglayvtedrkgygLNL 353

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  94 PEHelnkLRaEQISMifqdpmTSLNPYMRVGeqlmeVLMLHKGLGKAEAFeesvkmldavkmpeaRKRMRMFPH------ 167
Cdd:NF040905 354 IDD----IK-RNITL------ANLGKVSRRG-----VIDENEEIKVAEEY---------------RKKMNIKTPsvfqkv 402

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 168 -EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:NF040905 403 gNLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGVIVISSELPELLGMCDRIYVMNEGR 481

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

34-246

5.45e-12

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 66.69 E-value: 5.45e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlnlpehelnklraeqismifqDP 113
Cdd:NF033858 277 GDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASE---GEAWLFGQPV---------------------DA 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 mTSLNPYMRVG---------EQL--MEVLMLHkglgkAEAFEesvkmldavkMPEARKRMRM---------------FPH 167
Cdd:NF033858 333 -GDIATRRRVGymsqafslyGELtvRQNLELH-----ARLFH----------LPAAEIAARVaemlerfdladvadaLPD 396

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 168 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGvVAGICDKVLVMYAGR 246
Cdd:NF033858 397 SLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIELSREDGVTIFISTHFMN-EAERCDRISLMHAGR 474

40850658_otr

NF000106

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

34-262

5.12e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 60.13 E-value: 5.12e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQtafalmGLLAANgVIGGSAkfnGREILNLPEHELNKlRAEQISMIFQDP 113
Cdd:NF000106  24 GEVKAVDGVDLDVREGTVLGVLGP*GAA**R------GALPAH-V*GPDA---GRRPWRF*TWCANR-RALRRTIG*HRP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 MTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMfphEFSGGMRQRVMIAMALLCRPKLLIAD 193
Cdd:NF000106  93 VR*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAA---KYSGGMRRRLDLAASMIGRPAVLYLD 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 194 EPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEYGK---------ARDVFYQPAH 262
Cdd:NF000106 170 EPTTGLDPRTRNEVWDEVRSMVRDGAT-VLLTTQYMEEAEQLAHELTVIDRGRVIADGKvdelktkvgGRTLQIRPAH 246

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

49-231

8.76e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 50.83 E-value: 8.76e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173    49 GETLGIVGESGSGKSQTAFALMGLLAANGviGGSAKFNGREILNLPEHELNKlraeqismifqdpmtslnpymrvgeqlm 128
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPG--GGVIYIDGEDILEEVLDQLLL---------------------------- 51

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   129 evlmlhkglgkaeafeesvkmldavkmpearKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIM 208
Cdd:smart00382  52 -------------------------------IIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLL 100

                          170       180
                   ....*....|....*....|....*...
gi 556427173   209 -----TLLNELKREFNTAIIMITHDLGV 231
Cdd:smart00382 101 lleelRLLLLLKSEKNLTVILTTNDEKD 128

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

170-217

5.60e-04

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 41.65 E-value: 5.60e-04

                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 556427173 170 SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRE 217
Cdd:NF033858 138 SGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAE 185

Name

Accession

Description

Interval

E-value

oppD

PRK09473

oligopeptide transporter ATP-binding component; Provisional

8-337

0e+00

oligopeptide transporter ATP-binding component; Provisional

Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 784.68 E-value: 0e+00

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   8 TAPQAQQQNNLLLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKFNG 87
Cdd:PRK09473   1 TVPLAQQQADALLDVKDLRVTFSTPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSATFNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  88 REILNLPEHELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPH 167
Cdd:PRK09473  81 REILNLPEKELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEARKRMKMYPH 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 168 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRT 247
Cdd:PRK09473 161 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 248 MEYGKARDVFYQPAHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICNSAPPLEEFAPGRLR 327
Cdd:PRK09473 241 MEYGNARDVFYQPSHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSAPPLEEFGPGRLR 320

                        330
                 ....*....|
gi 556427173 328 ACFKPQEELV 337
Cdd:PRK09473 321 ACFKPVEELL 330

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

19-335

0e+00

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 556.59 E-value: 0e+00

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKFNGREILNLPEHEL 98
Cdd:COG0444    1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPGITSGEILFDGEDLLKLSEKEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQRVM 178
Cdd:COG0444   81 RKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDPERRLDRYPHELSGGMRQRVM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFY 258
Cdd:COG0444  161 IARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELFE 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 259 QPAHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEIC-NSAPPLEEFAPGRLRACFKPQEE 335
Cdd:COG0444  241 NPRHPYTRALLSSIPRLDPDGRRLIPIPGEPPSLLNPPSGCRFHPRCPYAMDRCrEEEPPLREVGPGHRVACHLYEEE 318

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

19-294

7.68e-147

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 424.48 E-value: 7.68e-147

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVI-GGSAKFNGREILNLPEHE 97
Cdd:COG4172    6 LLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDPAAHpSGSILFDGQDLLGLSERE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQRV 177
Cdd:COG4172   86 LRRIRGNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRLDAYPHQLSGGQRQRV 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVF 257
Cdd:COG4172  166 MIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAELF 245

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 556427173 258 YQPAHPYSIGLLNAVPRLDAegeslLTIPGNPPNLLR 294
Cdd:COG4172  246 AAPQHPYTRKLLAAEPRGDP-----RPVPPDAPPLLE 277

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

19-251

7.32e-125

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 357.20 E-value: 7.32e-125

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAangVIGGSAKFNGREILNLPEhEL 98
Cdd:cd03257    1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLK---PTSGSIIFDGKDLLKLSR-RL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEEsVKMLDAVKMPEARKRMRMFPHEFSGGMRQRVM 178
Cdd:cd03257   77 RKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKE-AVLLLLVGVGLPEEVLNRYPHELSGGQRQRVA 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03257  156 IARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228

AppF

COG4608

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...

19-334

2.58e-123

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 357.12 E-value: 2.58e-123

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTF-------KTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIL 91
Cdd:COG4608    7 LLEVRDLKKHFpvrgglfGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTS---GEILFDGQDIT 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  92 NLPEHELNKLRAeQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKM-PEARKRmrmFPHEFS 170
Cdd:COG4608   84 GLSGRELRPLRR-RMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLrPEHADR---YPHEFS 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEY 250
Cdd:COG4608  160 GGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEI 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 251 GKARDVFYQPAHPYSIGLLNAVPRLDAEGES---LLTipGNPPNLLRLPKGCPFQPRCPHAMEIC-NSAPPLEEFAPGRL 326
Cdd:COG4608  240 APRDELYARPLHPYTQALLSAVPVPDPERRReriVLE--GDVPSPLNPPSGCRFHTRCPYAQDRCaTEEPPLREVGPGHQ 317


                 ....*...
gi 556427173 327 RACFKPQE 334
Cdd:COG4608  318 VACHLAEE 325

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

19-278

3.33e-109

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 327.63 E-value: 3.33e-109

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKT-PDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHE 97
Cdd:COG1123  260 LLEVRNLSKRYPVrGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTS---GSILFDGKDLTKLSRRS 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNKLRAeQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARkrMRMFPHEFSGGMRQRV 177
Cdd:COG1123  337 LRELRR-RVQMVFQDPYSSLNPRMTVGDIIAEPLRLHGLLSRAERRERVAELLERVGLPPDL--ADRYPHELSGGQRQRV 413

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVF 257
Cdd:COG1123  414 AIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVF 493

                        250       260
                 ....*....|....*....|.
gi 556427173 258 YQPAHPYSIGLLNAVPRLDAE 278
Cdd:COG1123  494 ANPQHPYTRALLAAVPSLDPA 514

dppD

PRK11022

dipeptide transporter ATP-binding subunit; Provisional

19-332

6.26e-108

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 317.84 E-value: 6.26e-108

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANG-VIGGSAKFNGREILNLPEHE 97
Cdd:PRK11022   3 LLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGrVMAEKLEFNGQDLQRISEKE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQRV 177
Cdd:PRK11022  83 RRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQRV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVF 257
Cdd:PRK11022 163 MIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIF 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 258 YQPAHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICNSAPPLEEFAPGRLRACFKP 332
Cdd:PRK11022 243 RAPRHPYTQALLRALPEFAQDKARLASLPGVVPGKYDRPNGCLLNPRCPYATDRCRAEEPALNMLAGRQSKCHYP 317

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

19-295

1.24e-107

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 323.78 E-value: 1.24e-107

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKFNGREILNLPEHel 98
Cdd:COG1123    4 LLEVRDLSVRY--PGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGRISGEVLLDGRDLLELSEA-- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 nkLRAEQISMIFQDPMTSLNPyMRVGEQLMEVLMLHkGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVM 178
Cdd:COG1123   80 --LRGRRIGMVFQDPMTQLNP-VTVGDQIAEALENL-GLSRAEARARVLELLEAVGLERRLDR---YPHQLSGGQRQRVA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFY 258
Cdd:COG1123  153 IAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILA 232

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 556427173 259 QPAhpysigLLNAVPRLDAEGESLLTIPGNPPNLLRL 295
Cdd:COG1123  233 APQ------ALAAVPRLGAARGRAAPAAAAAEPLLEV 263

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

8-276

2.70e-98

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 300.45 E-value: 2.70e-98

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   8 TAPQAQQQNNLLLDVKDLRVTFKTPDG-------DVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngviG 80
Cdd:COG4172  264 DPRPVPPDAPPLLEARDLKVWFPIKRGlfrrtvgHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIPS----E 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  81 GSAKFNGREILNLPEHELNKLRAeQISMIFQDPMTSLNPYMRVGEQLMEVLMLHK-GLGKAEAFEESVKMLDAVKM-PEA 158
Cdd:COG4172  340 GEIRFDGQDLDGLSRRALRPLRR-RMQVVFQDPFGSLSPRMTVGQIIAEGLRVHGpGLSAAERRARVAEALEEVGLdPAA 418

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 159 RKRmrmFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDK 238
Cdd:COG4172  419 RHR---YPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHR 495

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 556427173 239 VLVMYAGRTMEYGKARDVFYQPAHPYSIGLLNAVPRLD 276
Cdd:COG4172  496 VMVMKDGKVVEQGPTEQVFDAPQHPYTRALLAAAPLLE 533

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

19-294

9.92e-98

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 298.93 E-value: 9.92e-98

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVI--GGSAKFNGREILNLPEH 96
Cdd:PRK15134   5 LLAIENLSVAFRQQQTVRTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLLPSPPVVypSGDIRFHGESLLHASEQ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  97 ELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQR 176
Cdd:PRK15134  85 TLRGVRGNKIAMIFQEPMVSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGGERQR 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 177 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:PRK15134 165 VMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATL 244

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 556427173 257 FYQPAHPYSIGLLNAVPRLDAegeslLTIPGNPPNLLR 294
Cdd:PRK15134 245 FSAPTHPYTQKLLNSEPSGDP-----VPLPEPASPLLD 277

PRK10261

glutathione transporter ATP-binding protein; Provisional

19-277

1.78e-93

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 290.60 E-value: 1.78e-93

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKF----NGREILNLP 94
Cdd:PRK10261  12 VLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMllrrRSRQVIELS 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  95 EH---ELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPHEFSG 171
Cdd:PRK10261  92 EQsaaQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQTILSRYPHQLSG 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 172 GMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:PRK10261 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETG 251

                        250       260
                 ....*....|....*....|....*.
gi 556427173 252 KARDVFYQPAHPYSIGLLNAVPRLDA 277
Cdd:PRK10261 252 SVEQIFHAPQHPYTRALLAAVPQLGA 277

PRK15079

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

14-331

4.95e-93

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 280.05 E-value: 4.95e-93

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  14 QQNNLLLDVKDLRVTFKTPDGD---------VTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAK 84
Cdd:PRK15079   3 EGKKVLLEVADLKVHFDIKDGKqwfwqppktLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATD---GEVA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  85 FNGREILNLPEHELNKLRAEqISMIFQDPMTSLNPYMRVGEQLMEVL-MLHKGLGKAEAFEESVKMLDAVKM-PEARKRm 162
Cdd:PRK15079  80 WLGKDLLGMKDDEWRAVRSD-IQMIFQDPLASLNPRMTIGEIIAEPLrTYHPKLSRQEVKDRVKAMMLKVGLlPNLINR- 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 163 rmFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVM 242
Cdd:PRK15079 158 --YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVM 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 243 YAGRTMEYGKARDVFYQPAHPYSIGLLNAVPRLDAEGESLLTI---PGNPPNLLRLPKGCPFQPRCPHAMEICNSAPPLE 319
Cdd:PRK15079 236 YLGHAVELGTYDEVYHNPLHPYTKALMSAVPIPDPDLERNKTIqllEGELPSPINPPSGCVFRTRCPIAGPECAKTRPVL 315

                        330
                 ....*....|..
gi 556427173 320 EFAPGRLRACFK 331
Cdd:PRK15079 316 EGSFRHAVSCLK 327

dppF

PRK11308

dipeptide transporter ATP-binding subunit; Provisional

15-336

9.24e-91

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 274.15 E-value: 9.24e-91

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  15 QNNLLLDVKDL-------RVTFKtPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMgllaangVI----GGSA 83
Cdd:PRK11308   1 SQQPLLQAIDLkkhypvkRGLFK-PERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLT-------MIetptGGEL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  84 KFNGREILNlPEHELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKM-PEARKRm 162
Cdd:PRK11308  73 YYQGQDLLK-ADPEAQKLLRQKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLrPEHYDR- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 163 rmFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVM 242
Cdd:PRK11308 151 --YPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVM 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 243 YAGRTMEYGKARDVFYQPAHPYSIGLLNAVPRLDAEGESL-LTIPGNPPNLLRLPKGCPFQPRCPHAMEICNS-APPLEE 320
Cdd:PRK11308 229 YLGRCVEKGTKEQIFNNPRHPYTQALLSATPRLNPDDRRErIKLTGELPSPLNPPPGCAFNARCPRAFGRCRQeQPQLRD 308

                        330
                 ....*....|....*.
gi 556427173 321 FApGRLRACFKPQEEL 336
Cdd:PRK11308 309 YD-GRLVACFAVEQDE 323

DppF

COG1124

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

19-278

2.92e-90

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 270.14 E-value: 2.92e-90

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlnlpEHEL 98
Cdd:COG1124    1 MLEVRNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWS---GEVTFDGRPV----TRRR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHkglGKAEAFEESVKMLDAVKMPEA-RKRmrmFPHEFSGGMRQRV 177
Cdd:COG1124   74 RKAFRRRVQMVFQDPYASLHPRHTVDRILAEPLRIH---GLPDREERIAELLEQVGLPPSfLDR---YPHQLSGGQRQRV 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVF 257
Cdd:COG1124  148 AIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLL 227

                        250       260
                 ....*....|....*....|.
gi 556427173 258 YQPAHPYSIGLLNAVPRLDAE 278
Cdd:COG1124  228 AGPKHPYTRELLAASLAFERA 248

SapD

COG4170

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

19-319

3.03e-90

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 272.93 E-value: 3.03e-90

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIggSA---KFNGREILNLPE 95
Cdd:COG4170    3 LLDIRNLTIEIDTPQGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNWHV--TAdrfRWNGIDLLKLSP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  96 HELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGK-----AEAFEESVKMLDAVKMPEARKRMRMFPHEFS 170
Cdd:COG4170   81 RERRKIIGREIAMIFQEPSSCLDPSAKIGDQLIEAIPSWTFKGKwwqrfKWRKKRAIELLHRVGIKDHKDIMNSYPHELT 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEY 250
Cdd:COG4170  161 EGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVES 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556427173 251 GKARDVFYQPAHPYSIGLLNAVP--RLDAEGESLL-TIPGNPPNLLRLPKGCPFQPRCPHAMEICNSAPPLE 319
Cdd:COG4170  241 GPTEQILKSPHHPYTKALLRSMPdfRQPLPHKSRLnTLPGSIPPLQHLPIGCRLGPRCPYAQKKCVETPRLR 312

nickel_nikD

TIGR02770

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...

38-271

5.20e-78

Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 238.42 E-value: 5.20e-78

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   38 AVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVI-GGSAKFNGREILNLpehelnKLRAEQISMIFQDPMTS 116
Cdd:TIGR02770   1 LVQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLTQtSGEILLDGRPLLPL------SIRGRHIATIMQNPRTA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  117 LNPYMRVGEQLMEVLMLHKGLGKaEAFEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPT 196
Cdd:TIGR02770  75 FNPLFTMGNHAIETLRSLGKLSK-QARALILEALEAVGLPDPEEVLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPT 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173  197 TALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPYSIGLLNA 271
Cdd:TIGR02770 154 TDLDVVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLSA 228

PRK15093

peptide ABC transporter ATP-binding protein SapD;

19-332

1.99e-74

peptide ABC transporter ATP-binding protein SapD;

Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 232.77 E-value: 1.99e-74

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAN-GVIGGSAKFNGREILNLPEHE 97
Cdd:PRK15093   3 LLDIRNLTIEFKTSDGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNwRVTADRMRFDDIDLLRLSPRE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVL--MLHKG-------LGKAEAFEesvkMLDAVKMPEARKRMRMFPHE 168
Cdd:PRK15093  83 RRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIpgWTYKGrwwqrfgWRKRRAIE----LLHRVGIKDHKDAMRSFPYE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 169 FSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTM 248
Cdd:PRK15093 159 LTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTV 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 249 EYGKARDVFYQPAHPYSIGLLNAVP---RLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICNSAPPLEEfAPGR 325
Cdd:PRK15093 239 ETAPSKELVTTPHHPYTQALIRAIPdfgSAMPHKSRLNTLPGAIPLLEHLPIGCRLGPRCPYAQRECIETPRLTG-AKNH 317


                 ....*..
gi 556427173 326 LRACFKP 332
Cdd:PRK15093 318 LYACHFP 324

SapF

COG4167

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];

19-271

1.24e-66

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];

Pssm-ID: 443328 [Multi-domain] Cd Length: 265 Bit Score: 210.46 E-value: 1.24e-66

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDG-----DVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlnl 93
Cdd:COG4167    4 LLEVRNLSKTFKYRTGlfrrqQFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTS---GEILINGHKL--- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  94 pEHELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKM-PEarkRMRMFPHEFSGG 172
Cdd:COG4167   78 -EYGDYKYRCKHIRMIFQDPNTSLNPRLNIGQILEEPLRLNTDLTAEEREERIFATLRLVGLlPE---HANFYPHMLSSG 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 173 MRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGK 252
Cdd:COG4167  154 QKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGK 233

                        250
                 ....*....|....*....
gi 556427173 253 ARDVFYQPAHPYSIGLLNA 271
Cdd:COG4167  234 TAEVFANPQHEVTKRLIES 252

PhnK

COG4107

ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and ...

19-272

3.35e-64

ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and metabolism];

Pssm-ID: 443283 [Multi-domain] Cd Length: 262 Bit Score: 203.89 E-value: 3.35e-64

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAAN-GVIGGSAKFNGRE-----ILN 92
Cdd:COG4107    8 LLSVRGLSKRYGPGCGTVVACRDVSFDLYPGEVLGIVGESGSGKS----TLLKCLYFDlAPTSGSVYYRDRDggprdLFA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  93 LPEHELNKLRAEQISMIFQDPMTSLNpyMRV------GEQLMEVLMLHKGLGKAEAFEesvkMLDAVKMPEARkrMRMFP 166
Cdd:COG4107   84 LSEAERRRLRRTDWGMVYQNPRDGLR--MDVsaggniAERLMAAGERHYGDIRARALE----WLERVEIPLER--IDDLP 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 167 HEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:COG4107  156 RTFSGGMQQRVQIARALVTNPRLLFLDEPTTGLDVSVQARLLDLIRRLQRELGLSMIVVTHDLGVIRLLADRTMVMKNGR 235

                        250       260
                 ....*....|....*....|....*.
gi 556427173 247 TMEYGKARDVFYQPAHPYSIGLLNAV 272
Cdd:COG4107  236 VVESGLTDQVLEDPQHPYTQLLVSSV 261

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

9-269

3.74e-64

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 211.87 E-value: 3.74e-64

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   9 APQAQQQNNLLLDVKDLRVTF-------KTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGg 81
Cdd:PRK15134 265 PVPLPEPASPLLDVEQLQVAFpirkgilKRTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLINSQGEIW- 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  82 sakFNGREILNLPEHELNKLRaEQISMIFQDPMTSLNPYMRVGEQLMEVLMLH-KGLGKAEAFEESVKMLDAVKM-PEAR 159
Cdd:PRK15134 344 ---FDGQPLHNLNRRQLLPVR-HRIQVVFQDPNSSLNPRLNVLQIIEEGLRVHqPTLSAAQREQQVIAVMEEVGLdPETR 419

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 160 KRmrmFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKV 239
Cdd:PRK15134 420 HR---YPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQV 496

                        250       260       270
                 ....*....|....*....|....*....|
gi 556427173 240 LVMYAGRTMEYGKARDVFYQPAHPYSIGLL 269
Cdd:PRK15134 497 IVLRQGEVVEQGDCERVFAAPQQEYTRQLL 526

LolD

COG1136

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

19-246

4.92e-62

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 197.19 E-value: 4.92e-62

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGLLAAngVIGGSAKFNGREILNLPEHEL 98
Cdd:COG1136    4 LLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKS-TLLNILGGLDR--PTSGEVLIDGQDISSLSEREL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRAEQISMIFQDPmtSLNPYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEarkRMRMFPHEFSGGMRQRVM 178
Cdd:COG1136   81 ARLRRRHIGFVFQFF--NLLPELTALENVALPLLL-AGVSRKERRERARELLERVGLGD---RLDHRPSQLSGGQQQRVA 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLgVVAGICDKVLVMYAGR 246
Cdd:COG1136  155 IARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDP-ELAARADRVIRLRDGR 221

PRK10261

glutathione transporter ATP-binding protein; Provisional

10-276

4.05e-61

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 205.86 E-value: 4.05e-61

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  10 PQAQQQNNL----LLDVKDLRVTFKTPDG-------DVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGv 78
Cdd:PRK10261 300 PPIEQDTVVdgepILQVRNLVTRFPLRSGllnrvtrEVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQG- 378

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  79 igGSAKFNGREILNLPEHELNKLRAEqISMIFQDPMTSLNPYMRVGEQLMEVLMLHkGLGKAEAFEESVK-MLDAVKM-P 156
Cdd:PRK10261 379 --GEIIFNGQRIDTLSPGKLQALRRD-IQFIFQDPYASLDPRQTVGDSIMEPLRVH-GLLPGKAAAARVAwLLERVGLlP 454

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 157 EARKRmrmFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGIC 236
Cdd:PRK10261 455 EHAWR---YPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERIS 531

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 556427173 237 DKVLVMYAGRTMEYGKARDVFYQPAHPYSIGLLNAVPRLD 276
Cdd:PRK10261 532 HRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLMAAVPVAD 571

ABC_MJ0796_LolCDE_FtsE

cd03255

ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...

20-246

9.69e-60

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.

Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 191.16 E-value: 9.69e-60

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGLLAAngVIGGSAKFNGREILNLPEHELN 99
Cdd:cd03255    1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKS-TLLNILGGLDR--PTSGEVRVDGTDISKLSEKELA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRAEQISMIFQDPmtSLNPYMRVGEQLMeVLMLHKGLGKAEAFEESVKMLDAVKMPEarkRMRMFPHEFSGGMRQRVMI 179
Cdd:cd03255   78 AFRRRHIGFVFQSF--NLLPDLTALENVE-LPLLLAGVPKKERRERAEELLERVGLGD---RLNHYPSELSGGQQQRVAI 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 180 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLgVVAGICDKVLVMYAGR 246
Cdd:cd03255  152 ARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDP-ELAEYADRIIELRDGK 217

nikD

PRK10418

nickel transporter ATP-binding protein NikD; Provisional

35-271

9.36e-55

nickel transporter ATP-binding protein NikD; Provisional

Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 179.51 E-value: 9.36e-55

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  35 DVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvigGSAKFNGREILNLPEHELNKLRAEQISMIFQDPM 114
Cdd:PRK10418  15 AQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPA-----GVRQTAGRVLLDGKPVAPCALRGRKIATIMQNPR 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 115 TSLNPYMRVGEQLMEVLmlhKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADE 194
Cdd:PRK10418  90 SAFNPLHTMHTHARETC---LALGKPADDATLTAALEAVGLENAARVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADE 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 195 PTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPYSIGLLNA 271
Cdd:PRK10418 167 PTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTRSLVSA 243

CcmA

COG1131

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

20-256

5.06e-52

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 171.79 E-value: 5.06e-52

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAF-ALMGLLAANGvigGSAKFNGREIlnlpEHEL 98
Cdd:COG1131    1 IEVRGLTKRY----GDKTALDGVSLTVEPGEIFGLLGPNGAGKT-TTIrMLLGLLRPTS---GEVRVLGEDV----ARDP 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRAeQISMIFQDPmtSLNPYMRVGEQLMEVLMLHkGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQRVM 178
Cdd:COG1131   69 AEVRR-RIGYVPQEP--ALYPDLTVRENLRFFARLY-GLPRKEARERIDELLELFGLTDAADRK---VGTLSGGMKQRLG 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:COG1131  142 LALALLHDPELLILDEPTSGLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDEL 218

AbcC

COG1135

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

22-295

1.29e-51

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 174.11 E-value: 1.29e-51

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  22 VKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTafaLMGLLaaNG---VIGGSAKFNGREILNLPEHEL 98
Cdd:COG1135    4 LENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKS-T---LIRCI--NLlerPTSGSVLVDGVDLTALSEREL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRAeQISMIFQDP--MTSLN-------PymrvgeqlMEVLmlhkGLGKAEAfEESVK-MLDAVKMPEARKRmrmFPHE 168
Cdd:COG1135   78 RAARR-KIGMIFQHFnlLSSRTvaenvalP--------LEIA----GVPKAEI-RKRVAeLLELVGLSDKADA---YPSQ 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 169 FSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTM 248
Cdd:COG1135  141 LSGGQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIV 220

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 556427173 249 EYGKARDVFYQPAHPYSIGLLNAVPRLDAEGESLLTIPGNPPN--LLRL 295
Cdd:COG1135  221 EQGPVLDVFANPQSELTRRFLPTVLNDELPEELLARLREAAGGgrLVRL 269

CP_lyasePhnK

TIGR02323

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...

19-272

1.99e-51

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]

Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 170.78 E-value: 1.99e-51

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGR-----EILNL 93
Cdd:TIGR02323   3 LLQVSGLSKSY----GGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDH---GTATYIMRsgaelELYQL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   94 PEHELNKLRAEQISMIFQDPMTSLNpyMRV------GEQLMEVLMLHKGLGKAEAfeesVKMLDAVKMPeaRKRMRMFPH 167
Cdd:TIGR02323  76 SEAERRRLMRTEWGFVHQNPRDGLR--MRVsaganiGERLMAIGARHYGNIRATA----QDWLEEVEID--PTRIDDLPR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  168 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRT 247
Cdd:TIGR02323 148 AFSGGMQQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRV 227

                         250       260
                  ....*....|....*....|....*
gi 556427173  248 MEYGKARDVFYQPAHPYSIGLLNAV 272
Cdd:TIGR02323 228 VESGLTDQVLDDPQHPYTQLLVSSI 252

ABC_MetN_methionine_transporter

cd03258

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...

22-260

2.80e-51

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 169.68 E-value: 2.80e-51

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  22 VKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGLLAANGviGGSAKFNGREILNLPEHELNKL 101
Cdd:cd03258    4 LKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKS-TLIRCINGLERPT--SGSVLVDGTDLTLLSGKELRKA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 102 RAeQISMIFQ--DPMTSLNpymrVGEQLMEVLMLHkGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMI 179
Cdd:cd03258   81 RR-RIGMIFQhfNLLSSRT----VFENVALPLEIA-GVPKAEIEERVLELLELVGLEDKADA---YPAQLSGGQKQRVGI 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 180 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQ 259
Cdd:cd03258  152 ARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFAN 231


                 .
gi 556427173 260 P 260
Cdd:cd03258  232 P 232

MlaF

COG1127

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...

19-264

1.60e-50

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 168.23 E-value: 1.60e-50

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHEL 98
Cdd:COG1127    5 MIEVRNLTKSF----GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDS---GEILVDGQDITGLSEKEL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRAeQISMIFQDP--MTSLNpymrVGEQLMEVLMLHKGLGKAEAfEESVKM-LDAVKMPEARKRMrmfPHEFSGGMRQ 175
Cdd:COG1127   78 YELRR-RIGMLFQGGalFDSLT----VFENVAFPLREHTDLSEAEI-RELVLEkLELVGLPGAADKM---PSELSGGMRK 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 176 RVMIAMALLCRPKLLIADEPTTALD-VTVqAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKAR 254
Cdd:COG1127  149 RVALARALALDPEILLYDEPTAGLDpITS-AVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPE 227

                        250
                 ....*....|
gi 556427173 255 DVFyQPAHPY 264
Cdd:COG1127  228 ELL-ASDDPW 236

YbbA

COG4181

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...

14-249

9.18e-50

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 165.68 E-value: 9.18e-50

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  14 QQNNLLLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAanG---VIGGSAKFNGREI 90
Cdd:COG4181    3 SSSAPIIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKS----TLLGLLA--GldrPTSGTVRLAGQDL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  91 LNLPEHELNKLRAEQISMIFQDPMtsLNPYMRVGEQLMEVLMLhkgLGKAEAFEESVKMLDAVKMPEarkRMRMFPHEFS 170
Cdd:COG4181   77 FALDEDARARLRARHVGFVFQSFQ--LLPTLTALENVMLPLEL---AGRRDARARARALLERVGLGH---RLDHYPAQLS 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGvVAGICDKVLVMYAGRTME 249
Cdd:COG4181  149 GGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPA-LAARCDRVLRLRAGRLVE 226

phnK

PRK11701

phosphonate C-P lyase system protein PhnK; Provisional

19-265

1.52e-49

phosphonate C-P lyase system protein PhnK; Provisional

Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 166.25 E-value: 1.52e-49

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGR-----EILNL 93
Cdd:PRK11701   6 LLSVRGLTKLY----GPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDA---GEVHYRMRdgqlrDLYAL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  94 PEHELNKLRAEQISMIFQDPMTSLNpyMRV------GEQLMEVLMLHKGLGKAEAfeesVKMLDAVKMPEARkrMRMFPH 167
Cdd:PRK11701  79 SEAERRRLLRTEWGFVHQHPRDGLR--MQVsaggniGERLMAVGARHYGDIRATA----GDWLERVEIDAAR--IDDLPT 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 168 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRT 247
Cdd:PRK11701 151 TFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRV 230

                        250
                 ....*....|....*...
gi 556427173 248 MEYGKARDVFYQPAHPYS 265
Cdd:PRK11701 231 VESGLTDQVLDDPQHPYT 248

EcfA2

COG1122

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...

20-260

1.10e-48

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];

Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 162.89 E-value: 1.10e-48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILnlpEHELN 99
Cdd:COG1122    1 IELENLSFSY---PGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTS---GEVLVDGKDIT---KKNLR 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRaEQISMIFQDP-----MTSlnpymrVGEqlmEVL--MLHKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGG 172
Cdd:COG1122   72 ELR-RKVGLVFQNPddqlfAPT------VEE---DVAfgPENLGLPREEIRERVEEALELVGLEHLADR---PPHELSGG 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 173 MRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGK 252
Cdd:COG1122  139 QKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGT 217


                 ....*...
gi 556427173 253 ARDVFYQP 260
Cdd:COG1122  218 PREVFSDY 225

ABC_cobalt_CbiO_domain1

cd03225

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...

27-246

1.88e-47

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 159.17 E-value: 1.88e-47

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLaanGVIGGSAKFNGREILNLPEHELnklrAEQI 106
Cdd:cd03225    5 LSFSYPDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLL---GPTSGEVLVDGKDLTKLSLKEL----RRKV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 107 SMIFQDPMTSL-NPymRVGEqlmEVL--MLHKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMIAMAL 183
Cdd:cd03225   78 GLVFQNPDDQFfGP--TVEE---EVAfgLENLGLPEEEIEERVEEALELVGLEGLRDR---SPFTLSGGQKQRVAIAGVL 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173 184 LCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:cd03225  150 AMDPDILLLDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211

PotA

COG3842

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...

19-328

1.79e-46

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 161.03 E-value: 1.79e-46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHEl 98
Cdd:COG3842    5 ALELENVSKRY----GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDS---GRILLDGRDVTGLPPEK- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 nklRaeQISMIFQDPmtSLNPYMRVGEQLMEVLMlHKGLGKAEAfEESVK-MLDAVKMPEARKRMrmfPHEFSGGMRQRV 177
Cdd:COG3842   77 ---R--NVGMVFQDY--ALFPHLTVAENVAFGLR-MRGVPKAEI-RARVAeLLELVGLEGLADRY---PHQLSGGQQQRV 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVF 257
Cdd:COG3842  145 ALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIY 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 258 YQPAHPYS---IGLLNAVP-RLDAEGESLLTIPGNPpnlLRLPKGCPFQP--------RcPHAMEIcnSAPPLEEFAPGR 325
Cdd:COG3842  225 ERPATRFVadfIGEANLLPgTVLGDEGGGVRTGGRT---LEVPADAGLAAggpvtvaiR-PEDIRL--SPEGPENGLPGT 298


                 ...
gi 556427173 326 LRA 328
Cdd:COG3842  299 VED 301

ABC_Org_Solvent_Resistant

cd03261

ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...

20-264

6.68e-46

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 156.12 E-value: 6.68e-46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALM-GLLAANGvigGSAKFNGREILNLPEHEL 98
Cdd:cd03261    1 IELRGLTKSF----GGRTVLKGVDLDVRRGEILAIIGPSGSGKS-TLLRLIvGLLRPDS---GEVLIDGEDISGLSEAEL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRAeQISMIFQDP--MTSLNpymrVGEQLMEVLMLHKGLGKAEaFEESVKM-LDAVKMPEARKRMrmfPHEFSGGMRQ 175
Cdd:cd03261   73 YRLRR-RMGMLFQSGalFDSLT----VFENVAFPLREHTRLSEEE-IREIVLEkLEAVGLRGAEDLY---PAELSGGMKK 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 176 RVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARD 255
Cdd:cd03261  144 RVALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEE 223


                 ....*....
gi 556427173 256 VFyQPAHPY 264
Cdd:cd03261  224 LR-ASDDPL 231

nickel_nikE

TIGR02769

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...

19-272

2.33e-45

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 155.73 E-value: 2.33e-45

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   19 LLDVKDLRVTFKT-----PDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNL 93
Cdd:TIGR02769   2 LLEVRDVTHTYRTgglfgAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQ---GTVSFRGQDLYQL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   94 PEHELNKLRAEqISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEarKRMRMFPHEFSGGM 173
Cdd:TIGR02769  79 DRKQRRAFRRD-VQLVFQDSPSAVNPRMTVRQIIGEPLRHLTSLDESEQKARIAELLDMVGLRS--EDADKLPRQLSGGQ 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  174 RQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKA 253
Cdd:TIGR02769 156 LQRINIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDV 235

                         250
                  ....*....|....*....
gi 556427173  254 RDVFyQPAHPYSIGLLNAV 272
Cdd:TIGR02769 236 AQLL-SFKHPAGRNLQSAV 253

FepC

COG1120

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...

19-257

2.50e-45

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];

Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 155.20 E-value: 2.50e-45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAF-ALMGLLAAngvIGGSAKFNGREILNLPEHE 97
Cdd:COG1120    1 MLEAENLSVGY----GGRPVLDDVSLSLPPGEVTALLGPNGSGKS-TLLrALAGLLKP---SSGEVLLDGRDLASLSRRE 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 lnklRAEQISMIFQDPMTSLNpyMRVgeqlMEVLML----HKGLG---KAEAFEESVKMLDAVKMpeARKRMRMFpHEFS 170
Cdd:COG1120   73 ----LARRIAYVPQEPPAPFG--LTV----RELVALgrypHLGLFgrpSAEDREAVEEALERTGL--EHLADRPV-DELS 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEY 250
Cdd:COG1120  140 GGERQRVLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQ 219


                 ....*..
gi 556427173 251 GKARDVF 257
Cdd:COG1120  220 GPPEEVL 226

TauB

COG1116

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...

19-242

3.64e-45

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 154.86 E-value: 3.64e-45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAF-ALMGLLAANGvigGSAKFNGREILNLPEHe 97
Cdd:COG1116    7 ALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKS-TLLrLIAGLEKPTS---GEVLVDGKPVTGPGPD- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 lnklraeqISMIFQDPmtSLNPYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRV 177
Cdd:COG1116   82 --------RGVVFQEP--ALLPWLTVLDNVALGLEL-RGVPKAERRERARELLELVGLAGFEDA---YPHQLSGGMRQRV 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVM 242
Cdd:COG1116  148 AIARALANDPEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVL 212

PRK15112

peptide ABC transporter ATP-binding protein SapF;

19-262

1.37e-44

peptide ABC transporter ATP-binding protein SapF;

Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 153.79 E-value: 1.37e-44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDG-----DVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGviggsakfngREILnL 93
Cdd:PRK15112   4 LLEVRNLSKTFRYRTGwfrrqTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTS----------GELL-I 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  94 PEHELN----KLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMpeARKRMRMFPHEF 169
Cdd:PRK15112  73 DDHPLHfgdySYRSQRIRMIFQDPSTSLNPRQRISQILDFPLRLNTDLEPEQREKQIIETLRQVGL--LPDHASYYPHML 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 170 SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTME 249
Cdd:PRK15112 151 APGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVE 230

                        250
                 ....*....|...
gi 556427173 250 YGKARDVFYQPAH 262
Cdd:PRK15112 231 RGSTADVLASPLH 243

ABC_NrtD_SsuB_transporters

cd03293

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...

20-242

6.31e-44

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 150.31 E-value: 6.31e-44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTafaLMGLLAanGVI---GGSAKFNGREIlnlpeh 96
Cdd:cd03293    1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKS-T---LLRIIA--GLErptSGEVLVDGEPV------ 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  97 elnKLRAEQISMIFQDPmtSLNPYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQR 176
Cdd:cd03293   69 ---TGPGPDRGYVFQQD--ALLPWLTVLDNVALGLEL-QGVPKAEARERAEELLELVGLSGFENA---YPHQLSGGMRQR 139

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556427173 177 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVM 242
Cdd:cd03293  140 VALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205

ABC_DR_subfamily_A

cd03230

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...

20-246

1.12e-43

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 147.93 E-value: 1.12e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEheln 99
Cdd:cd03230    1 IEVRNLSKRY----GKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDS---GEIKVLGKDIKKEPE---- 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRaEQISMIFQDPmtSLNPYMRVGEQLmevlmlhkglgkaeafeesvkmldavkmpearkrmrmfphEFSGGMRQRVMI 179
Cdd:cd03230   70 EVK-RRIGYLPEEP--SLYENLTVRENL----------------------------------------KLSGGMKQRLAL 106

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 180 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:cd03230  107 AQALLHDPELLILDEPTSGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGR 172

ZnuC

COG1121

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...

19-257

2.65e-43

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 149.47 E-value: 2.65e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAF-ALMGLLAangVIGGSAKFNGREIlnlpehe 97
Cdd:COG1121    6 AIELENLTVSY----GGRPVLEDVSLTIPPGEFVAIVGPNGAGKS-TLLkAILGLLP---PTSGTVRLFGKPP------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 lnKLRAEQISMIFQdpMTSLNPY--MRVgeqlMEVLML----HKGLGK---AEAFEESVKMLDAVKMPE-ARKRMRmfph 167
Cdd:COG1121   71 --RRARRRIGYVPQ--RAEVDWDfpITV----RDVVLMgrygRRGLFRrpsRADREAVDEALERVGLEDlADRPIG---- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 168 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMyAGRT 247
Cdd:COG1121  139 ELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLLL-NRGL 216

                        250
                 ....*....|
gi 556427173 248 MEYGKARDVF 257
Cdd:COG1121  217 VAHGPPEEVL 226

LolD_lipo_ex

TIGR02211

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...

19-246

3.14e-43

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 148.65 E-value: 3.14e-43

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHEL 98
Cdd:TIGR02211   1 LLKCENLGKRYQEGKLDTRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTS---GEVLFNGQSLSKLSSNER 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   99 NKLRAEQISMIFQdpMTSLNPYMRVGEQLMeVLMLHKGLGKAEAFEESVKMLDAVKMpeaRKRMRMFPHEFSGGMRQRVM 178
Cdd:TIGR02211  78 AKLRNKKLGFIYQ--FHHLLPDFTALENVA-MPLLIGKKSVKEAKERAYEMLEKVGL---EHRINHRPSELSGGERQRVA 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173  179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGvVAGICDKVLVMYAGR 246
Cdd:TIGR02211 152 IARALVNQPSLVLADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLE-LAKKLDRVLEMKDGQ 218

ABC_Carb_Solutes_like

cd03259

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...

20-251

6.90e-43

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 147.28 E-value: 6.90e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELN 99
Cdd:cd03259    1 LELKGLSKTY----GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDS---GEILIDGRDVTGVPPERRN 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 klraeqISMIFQDPmtSLNPYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMI 179
Cdd:cd03259   74 ------IGMVFQDY--ALFPHLTVAENIAFGLKL-RGVPKAEIRARVRELLELVGLEGLLNR---YPHELSGGQQQRVAL 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556427173 180 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03259  142 ARALAREPSLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213

nikE

PRK10419

nickel ABC transporter ATP-binding protein NikE;

37-272

9.91e-43

nickel ABC transporter ATP-binding protein NikE;

Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 148.68 E-value: 9.91e-43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  37 TAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELNKLRAEqISMIFQDPMTS 116
Cdd:PRK10419  26 TVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQ---GNVSWRGEPLAKLNRAQRKAFRRD-IQMVFQDSISA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 117 LNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPE--ARKRmrmfPHEFSGGMRQRVMIAMALLCRPKLLIADE 194
Cdd:PRK10419 102 VNPRKTVREIIREPLRHLLSLDKAERLARASEMLRAVDLDDsvLDKR----PPQLSGGQLQRVCLARALAVEPKLLILDE 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 195 PTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGK--ARDVFyqpAHPYSIGLLNAV 272
Cdd:PRK10419 178 AVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQPvgDKLTF---SSPAGRVLQNAV 254

GlnQ

COG1126

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...

19-263

4.02e-42

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 146.29 E-value: 4.02e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAF-ALMGLLAANGvigGSAKFNGREIlNLPEHE 97
Cdd:COG1126    1 MIEIENLHKSF----GDLEVLKGISLDVEKGEVVVIIGPSGSGKS-TLLrCINLLEEPDS---GTITVDGEDL-TDSKKD 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNKLRAEqISMIFQdpmtSLN--PYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEarkRMRMFPHEFSGGMRQ 175
Cdd:COG1126   72 INKLRRK-VGMVFQ----QFNlfPHLTVLENVTLAPIKVKKMSKAEAEERAMELLERVGLAD---KADAYPAQLSGGQQQ 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 176 RVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARD 255
Cdd:COG1126  144 RVAIARALAMEPKVMLFDEPTSALDPELVGEVLDVMRDLAKEGMT-MVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEE 222


                 ....*...
gi 556427173 256 VFYQPAHP 263
Cdd:COG1126  223 FFENPQHE 230

metN

PRK11153

DL-methionine transporter ATP-binding subunit; Provisional

23-263

5.33e-42

DL-methionine transporter ATP-binding subunit; Provisional

Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 148.80 E-value: 5.33e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  23 KDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGLLaaNGVIGGSAKFNGREILNLPEHELNKLR 102
Cdd:PRK11153   5 KNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKS-TLIRCINLL--ERPTSGRVLVDGQDLTALSEKELRKAR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 103 aEQISMIFQ--DPMTSLNPYMRVGEQLmEVlmlhKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMIA 180
Cdd:PRK11153  82 -RQIGMIFQhfNLLSSRTVFDNVALPL-EL----AGTPKAEIKARVTELLELVGLSDKADR---YPAQLSGGQKQRVAIA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 181 MALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQP 260
Cdd:PRK11153 153 RALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHP 232


                 ...
gi 556427173 261 AHP 263
Cdd:PRK11153 233 KHP 235

ABC_Class3

cd03229

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...

20-246

5.64e-42

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 143.87 E-value: 5.64e-42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREIlNLPEHELN 99
Cdd:cd03229    1 LELKNVSKRY----GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEP---DSGSILIDGEDL-TDLEDELP 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRaEQISMIFQDPmtSLNPYMRVGEQLMEVLmlhkglgkaeafeesvkmldavkmpearkrmrmfphefSGGMRQRVMI 179
Cdd:cd03229   73 PLR-RRIGMVFQDF--ALFPHLTVLENIALGL--------------------------------------SGGQQQRVAL 111

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 180 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:cd03229  112 ARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178

ABC_Mj1267_LivG_branched

cd03219

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...

20-256

1.33e-41

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).

Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 144.89 E-value: 1.33e-41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAF-ALMGLLAANGvigGSAKFNGREILNLPEHEL 98
Cdd:cd03219    1 LEVRGLTKRF----GGLVALDDVSFSVRPGEIHGLIGPNGAGKT-TLFnLISGFLRPTS---GSVLFDGEDITGLPPHEI 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKL---RAEQISMIFQDpMTSL-NpyMRVGEQLME---VLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSG 171
Cdd:cd03219   73 ARLgigRTFQIPRLFPE-LTVLeN--VMVAAQARTgsgLLLARARREEREARERAEELLERVGLADLADRP---AGELSY 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 172 GMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELkREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03219  147 GQQRRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIREL-RERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEG 225


                 ....*
gi 556427173 252 KARDV 256
Cdd:cd03219  226 TPDEV 230

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

39-197

3.41e-41

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 140.86 E-value: 3.41e-41

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   39 VNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREILNLPEHELNKlraeQISMIFQDPmtSLN 118
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSP---TEGTILLDGQDLTDDERKSLRK----EIGYVFQDP--QLF 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  119 PYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEARKR-MRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTT 197
Cdd:pfam00005  72 PRLTVRENLRLGLLL-KGLSKREKDARAEEALEKLGLGDLADRpVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150

ABC_Iron-Siderophores_B12_Hemin

cd03214

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...

21-251

4.22e-41

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.

Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 141.80 E-value: 4.22e-41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  21 DVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAF-ALMGLLAANGvigGSAKFNGREILNLPEHELN 99
Cdd:cd03214    1 EVENLSVGY----GGRTVLDDLSLSIEAGEIVGILGPNGAGKS-TLLkTLAGLLKPSS---GEILLDGKDLASLSPKELA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRAeqismifqdpmtslnpYMrvgEQLMEVL-MLHKglgkaeafeesvkmldavkmpearkRMRMFpHEFSGGMRQRVM 178
Cdd:cd03214   73 RKIA----------------YV---PQALELLgLAHL-------------------------ADRPF-NELSGGERQRVL 107

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03214  108 LARALAQEPPILLLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180

FtsE

COG2884

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

30-246

1.33e-40

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 141.73 E-value: 1.33e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  30 KTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQtafaLMGLLAAngvI----GGSAKFNGREILNLPEHELNKLRaEQ 105
Cdd:COG2884    9 KRYPGGREALSDVSLEIEKGEFVFLTGPSGAGKST----LLKLLYG---EerptSGQVLVNGQDLSRLKRREIPYLR-RR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 106 ISMIFQDpmTSLNPYMRVGEQLMEVLMLHkGLGKAEAFEESVKMLDAVKMpeaRKRMRMFPHEFSGGMRQRVMIAMALLC 185
Cdd:COG2884   81 IGVVFQD--FRLLPDRTVYENVALPLRVT-GKSRKEIRRRVREVLDLVGL---SDKAKALPHELSGGEQQRVAIARALVN 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556427173 186 RPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:COG2884  155 RPELLLADEPTGNLDPETSWEIMELLEEINRR-GTTVLIATHDLELVDRMPKRVLELEDGR 214

ABC_subfamily_A

cd03263

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...

20-251

1.55e-40

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.

Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 141.49 E-value: 1.55e-40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFKTpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNlpehELN 99
Cdd:cd03263    1 LQIRNLTKTYKK--GTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTS---GTAYINGYSIRT----DRK 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRAEqISMIFQDPMtsLNPYMRVgeqlMEVLMLH---KGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQR 176
Cdd:cd03263   72 AARQS-LGYCPQFDA--LFDELTV----REHLRFYarlKGLPKSEIKEEVELLLRVLGLTDKANK---RARTLSGGMKRK 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 177 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03263  142 LSLAIALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLRCIG 214

ABC_PotA_N

cd03300

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...

34-261

1.15e-39

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 139.68 E-value: 1.15e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTafaLMGLLAANGVIGGSAKFNGREILNLPEHElnklraEQISMIFQDp 113
Cdd:cd03300   11 GGFVALDGVSLDIKEGEFFTLLGPSGCGKTTL---LRLIAGFETPTSGEILLDGKDITNLPPHK------RPVNTVFQN- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 mTSLNPYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQRVMIAMALLCRPKLLIAD 193
Cdd:cd03300   81 -YALFPHLTVFENIAFGLRL-KKLPKAEIKERVAEALDLVQLEGYANRK---PSQLSGGQQQRVAIARALVNEPKVLLLD 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 194 EPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPA 261
Cdd:cd03300  156 EPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPA 223

PhnC

COG3638

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...

19-256

1.88e-39

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 139.42 E-value: 1.88e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAF-ALMGLLAANGvigGSAKFNGREILNLPEHE 97
Cdd:COG3638    2 MLELRNLSKRY---PGGTPALDDVSLEIERGEFVALIGPSGAGKS-TLLrCLNGLVEPTS---GEILVDGQDVTALRGRA 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNKLRAeQISMIFQDPmtSLNPYMRVgeqLMEVLM-------LHKGL-------GKAEAFE--ESVKMLDavkmpEARKR 161
Cdd:COG3638   75 LRRLRR-RIGMIFQQF--NLVPRLSV---LTNVLAgrlgrtsTWRSLlglfppeDRERALEalERVGLAD-----KAYQR 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 162 mrmfPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLV 241
Cdd:COG3638  144 ----ADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIG 219

                        250
                 ....*....|....*
gi 556427173 242 MYAGRTMEYGKARDV 256
Cdd:COG3638  220 LRDGRVVFDGPPAEL 234

ECF_ATPase_1

TIGR04520

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...

27-273

3.30e-39

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]

Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 139.49 E-value: 3.30e-39

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   27 VTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNlpEHELNKLRaEQI 106
Cdd:TIGR04520   6 VSFSYPESEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTS---GKVTVDGLDTLD--EENLWEIR-KKV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  107 SMIFQDPMTSLnpymrVGEQL-------MEVLMLhkglgKAEAFEESVKM-LDAVKMPEARKRMrmfPHEFSGGMRQRVM 178
Cdd:TIGR04520  80 GMVFQNPDNQF-----VGATVeddvafgLENLGV-----PREEMRKRVDEaLKLVGMEDFRDRE---PHLLSGGQKQRVA 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGiCDKVLVMYAGRTMEYGKARDVFY 258
Cdd:TIGR04520 147 IAGVLAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAVL-ADRVIVMNKGKIVAEGTPREIFS 225

                         250
                  ....*....|....*
gi 556427173  259 QPAHPYSIGLlnAVP 273
Cdd:TIGR04520 226 QVELLKEIGL--DVP 238

ABC_ATPase

cd00267

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...

22-246

5.48e-39

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 135.45 E-value: 5.48e-39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  22 VKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAangVIGGSAKFNGREILNLPEHELNKl 101
Cdd:cd00267    2 IENLSFRY----GGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLK---PTSGEILIDGKDIAKLPLEELRR- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 102 raeQISMIFQdpmtslnpymrvgeqlmevlmlhkglgkaeafeesvkmldavkmpearkrmrmfpheFSGGMRQRVMIAM 181
Cdd:cd00267   74 ---RIGYVPQ---------------------------------------------------------LSGGQRQRVALAR 93

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 182 ALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:cd00267   94 ALLLNPDLLLLDEPTSGLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157

ABC_PhnC_transporter

cd03256

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...

20-256

1.09e-38

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 137.31 E-value: 1.09e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFKtpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLaaNGVI---GGSAKFNGREILNLPEH 96
Cdd:cd03256    1 IEVENLSKTYP---NGKKALKDVSLSINPGEFVALIGPSGAGKS----TLLRCL--NGLVeptSGSVLIDGTDINKLKGK 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  97 ELNKLRAeQISMIFQDPmtSLNPYMRVGEQLMEVLMLHKGLGKA-------EAFEESVKMLDAVKMPE-ARKRMRmfphE 168
Cdd:cd03256   72 ALRQLRR-QIGMIFQQF--NLIERLSVLENVLSGRLGRRSTWRSlfglfpkEEKQRALAALERVGLLDkAYQRAD----Q 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 169 FSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTM 248
Cdd:cd03256  145 LSGGQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIV 224


                 ....*...
gi 556427173 249 EYGKARDV 256
Cdd:cd03256  225 FDGPPAEL 232

ABC_Metallic_Cations

cd03235

ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...

22-242

1.64e-38

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.

Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 136.12 E-value: 1.64e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  22 VKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAF-ALMGLLAAngvIGGSAKFNGREILN-------L 93
Cdd:cd03235    2 VEDLTVSY----GGHPVLEDVSFEVKPGEFLAIVGPNGAGKS-TLLkAILGLLKP---TSGSIRVFGKPLEKerkrigyV 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  94 PEHElnklraeqismifqdpmtSLNPYM--RVGEQLMEVLMLHKGLGK---AEAFEESVKMLDAVKMPE-ARKRMRmfph 167
Cdd:cd03235   74 PQRR------------------SIDRDFpiSVRDVVLMGLYGHKGLFRrlsKADKAKVDEALERVGLSElADRQIG---- 131

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 168 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVM 242
Cdd:cd03235  132 ELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLL 205

NatA

COG4555

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...

19-251

2.31e-38

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];

Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 136.53 E-value: 2.31e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREilnlPEHEL 98
Cdd:COG4555    1 MIEVENLSKKY----GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDS---GSILIDGED----VRKEP 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRaEQISMIFQDPMtsLNPYMRVGEQLMEVLMLHKGLGKA--EAFEESVKMLDavkMPEARKRmRMfpHEFSGGMRQR 176
Cdd:COG4555   70 REAR-RQIGVLPDERG--LYDRLTVRENIRYFAELYGLFDEElkKRIEELIELLG---LEEFLDR-RV--GELSTGMKKK 140

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 177 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:COG4555  141 VALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALKKE-GKTVLFSSHIMQEVEALCDRVVILHKGKVVAQG 214

CysA

COG1118

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...

20-278

2.55e-38

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 139.13 E-value: 2.55e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIL-NLPEHEL 98
Cdd:COG1118    3 IEVRNISKRF----GSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDS---GRIVLNGRDLFtNLPPRER 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NklraeqISMIFQDPMtsLNPYMRVGEQL---MEVlmlhKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQ 175
Cdd:COG1118   76 R------VGFVFQHYA--LFPHMTVAENIafgLRV----RPPSKAEIRARVEELLELVQLEGLADR---YPSQLSGGQRQ 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 176 RVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARD 255
Cdd:COG1118  141 RVALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDE 220

                        250       260
                 ....*....|....*....|...
gi 556427173 256 VFYQPAHPYSIGLLNAVPRLDAE 278
Cdd:COG1118  221 VYDRPATPFVARFLGCVNVLRGR 243

ABCC_MRP_Like

cd03228

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...

27-246

5.34e-38

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 133.28 E-value: 5.34e-38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELNKlraeQI 106
Cdd:cd03228    6 VSFSYPGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTS---GEILIDGVDLRDLDLESLRK----NI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 107 SMIFQDPmtslnpymrvgeqlmeVLmlhkglgkaeaFEESVKmldavkmpearkrmrmfphE--FSGGMRQRVMIAMALL 184
Cdd:cd03228   79 AYVPQDP----------------FL-----------FSGTIR-------------------EniLSGGQRQRIAIARALL 112

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556427173 185 CRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAgICDKVLVMYAGR 246
Cdd:cd03228  113 RDPPILILDEATSALDPETEALILEALRALAK--GKTVIVIAHRLSTIR-DADRIIVLDDGR 171

ABC_Pro_Gly_Betaine

cd03294

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...

34-264

1.49e-37

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 135.08 E-value: 1.49e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLaaNGVI---GGSAKFNGREILNLPEHELNKLRAEQISMIF 110
Cdd:cd03294   35 GQTVGVNDVSLDVREGEIFVIMGLSGSGKS----TLLRCI--NRLIeptSGKVLIDGQDIAAMSRKELRELRRKKISMVF 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 111 QDpmTSLNPYMRVGEQL---MEVlmlhKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMIAMALLCRP 187
Cdd:cd03294  109 QS--FALLPHRTVLENVafgLEV----QGVPRAEREERAAEALELVGLEGWEHK---YPDELSGGMQQRVGLARALAVDP 179

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 188 KLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPY 264
Cdd:cd03294  180 DILLMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDY 256

heterocyst_DevA

TIGR02982

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ...

40-246

6.10e-37

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.

Pssm-ID: 274374 [Multi-domain] Cd Length: 220 Bit Score: 132.06 E-value: 6.10e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   40 NDLNFNLRAGETLGIVGESGSGKSqTAFALMGLLAAngVIGGSAKFNGREILNLPEHELNKLRaEQISMIFQDpmTSLNP 119
Cdd:TIGR02982  22 FDINLEINPGEIVILTGPSGSGKT-TLLTLIGGLRS--VQEGSLKVLGQELHGASKKQLVQLR-RRIGYIFQA--HNLLG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  120 YMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMpeaRKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTAL 199
Cdd:TIGR02982  96 FLTARQNVQMALELQPNLSYQEARERARAMLEAVGL---GDHLNYYPHNLSGGQKQRVAIARALVHHPKLVLADEPTAAL 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 556427173  200 DVTVQAQIMTLLNELKREFNTAIIMITHDlGVVAGICDKVLVMYAGR 246
Cdd:TIGR02982 173 DSKSGRDVVELMQKLAKEQGCTILMVTHD-NRILDVADRILQMEDGK 218

FetA

COG4619

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

20-246

8.03e-37

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 131.48 E-value: 8.03e-37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELN 99
Cdd:COG4619    1 LELEGLSFRV----GGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTS---GEIYLDGKPLSAMPPPEWR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KlraeQISMIFQDPmtSLnPYMRVGEQLMEVLMLHKGLGKAEAFEEsvkMLDAVKMPEA--RKRMrmfpHEFSGGMRQRV 177
Cdd:COG4619   74 R----QVAYVPQEP--AL-WGGTVRDNLPFPFQLRERKFDRERALE---LLERLGLPPDilDKPV----ERLSGGERQRL 139

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:COG4619  140 ALIRALLLQPDVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGR 208

YhaQ

COG4152

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

20-256

1.44e-36

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 133.31 E-value: 1.44e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREI----LN--- 92
Cdd:COG4152    2 LELKGLTKRF----GDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDS---GEVLWDGEPLdpedRRrig 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  93 -LPEhElnklRaeqismifqdpmtSLNPYMRVGEQLMEVLMLHkGLGKAEAFEESVKMLDAVKMPEARKRMRmfpHEFSG 171
Cdd:COG4152   75 yLPE-E----R-------------GLYPKMKVGEQLVYLARLK-GLSKAEAKRRADEWLERLGLGDRANKKV---EELSK 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 172 GMRQRVMIAMALLCRPKLLIADEPTTALD-VTVQAqIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEY 250
Cdd:COG4152  133 GNQQKVQLIAALLHDPELLILDEPFSGLDpVNVEL-LKDVIRELAAK-GTTVIFSSHQMELVEELCDRIVIINKGRKVLS 210


                 ....*.
gi 556427173 251 GKARDV 256
Cdd:COG4152  211 GSVDEI 216

ABC_DrrA

cd03265

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...

20-246

5.22e-36

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 129.80 E-value: 5.22e-36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNlpehELN 99
Cdd:cd03265    1 IEVENLVKKY----GDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTS---GRATVAGHDVVR----EPR 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRaEQISMIFQDPmtSLNPYMrVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQRVMI 179
Cdd:cd03265   70 EVR-RRIGIVFQDL--SVDDEL-TGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRL---VKTYSGGMRRRLEI 142

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 180 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:cd03265  143 ARSLVHRPEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGR 209

ABC_putative_ATPase

cd03269

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...

20-251

1.62e-35

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 128.17 E-value: 1.62e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELN 99
Cdd:cd03269    1 LEVENVTKRF----GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDS---GEVLFDGKPLDIAARNRIG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRAEQismifqdpmtSLNPYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPE-ARKRMRmfphEFSGGMRQRVM 178
Cdd:cd03269   74 YLPEER----------GLYPKMKVIDQLVYLAQL-KGLKKEEARRRIDEWLERLELSEyANKRVE----ELSKGNQQKVQ 138

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03269  139 FIAAVIHDPELLILDEPFSGLDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210

ABC_PstB_phosphate_transporter

cd03260

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...

20-256

2.19e-35

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).

Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 128.07 E-value: 2.19e-35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQT--AFALMGLLAANGVIGGSAKFNGREILNLPEHE 97
Cdd:cd03260    1 IELRDLNVYY----GDKHALKDISLDIPKGEITALIGPSGCGKSTLlrLLNRLNDLIPGAPDEGEVLLDGKDIYDLDVDV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNkLRAeQISMIFQDPmtslNPY-MRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRmRMFPHEFSGGMRQR 176
Cdd:cd03260   77 LE-LRR-RVGMVFQKP----NPFpGSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDEVKD-RLHALGLSGGQQQR 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 177 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfnTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:cd03260  150 LCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227

ABC_phnC

TIGR02315

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...

19-256

3.65e-35

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]

Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 128.18 E-value: 3.65e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   19 LLDVKDLRVTFktpDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLlaaNGVIGGSAKFNGREILNLPEHEL 98
Cdd:TIGR02315   1 MLEVENLSKVY---PNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRL---VEPSSGSILLEGTDITKLRGKKL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   99 NKLRAeQISMIFQD-----PMTSL-NPYM-RVGEQ--LMEVLMLHKGLGKAEAFEesvkMLDAVKMPE-ARKRMRmfphE 168
Cdd:TIGR02315  75 RKLRR-RIGMIFQHynlieRLTVLeNVLHgRLGYKptWRSLLGRFSEEDKERALS----ALERVGLADkAYQRAD----Q 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  169 FSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTM 248
Cdd:TIGR02315 146 LSGGQQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIV 225


                  ....*...
gi 556427173  249 EYGKARDV 256
Cdd:TIGR02315 226 FDGAPSEL 233

L_ocin_972_ABC

TIGR03608

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...

34-240

9.58e-35

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]

Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 125.81 E-value: 9.58e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGLLaaNGVIGGSAKFNGREILNLPEHELNKLRAEQISMIFQDp 113
Cdd:TIGR03608   9 GDKVILDDLNLTIEKGKMYAIIGESGSGKS-TLLNIIGLL--EKFDSGQVYLNGQETPPLNSKKASKFRREKLGYLFQN- 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  114 mTSLNPYMRVGEQLMEVLMLHKgLGKAEAFEESVKMLDAVKMpeaRKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIAD 193
Cdd:TIGR03608  85 -FALIENETVEENLDLGLKYKK-LSKKEKREKKKEALEKVGL---NLKLKQKIYELSGGEQQRVALARAILKPPPLILAD 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 556427173  194 EPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLgVVAGICDKVL 240
Cdd:TIGR03608 160 EPTGSLDPKNRDEVLDLLLELNDE-GKTIIIVTHDP-EVAKQADRVI 204

ABC_ModC_like

cd03299

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...

41-260

1.75e-34

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 126.30 E-value: 1.75e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  41 DLNFNLRAGETLGIVGESGSGKSQTAFALMGLLaanGVIGGSAKFNGREILNLPEHElnklraEQISMIFQDpmTSLNPY 120
Cdd:cd03299   17 NVSLEVERGDYFVILGPTGSGKSVLLETIAGFI---KPDSGKILLNGKDITNLPPEK------RDISYVPQN--YALFPH 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 121 MRVGEQLmEVLMLHKGLGKAEAFEesvKMLDAVKMPEARKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALD 200
Cdd:cd03299   86 MTVYKNI-AYGLKKRKVDKKEIER---KVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALD 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 201 VTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQP 260
Cdd:cd03299  162 VRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKP 221

ABC_HisP_GlnQ

cd03262

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...

20-246

2.70e-34

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.

Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 124.95 E-value: 2.70e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlNLPEHELN 99
Cdd:cd03262    1 IEIKNLHKSF----GDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDS---GTIIIDGLKL-TDDKKNIN 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRAEqISMIFQDpmTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEarkRMRMFPHEFSGGMRQRVMI 179
Cdd:cd03262   73 ELRQK-VGMVFQQ--FNLFPHLTVLENITLAPIKVKGMSKAEAEERALELLEKVGLAD---KADAYPAQLSGGQQQRVAI 146

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 180 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:cd03262  147 ARALAMNPKVMLFDEPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDGR 212

ABC_OpuCA_Osmoprotection

cd03295

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...

26-264

7.40e-34

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 124.72 E-value: 7.40e-34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  26 RVTFKTPDGDvTAVNDLNFNLRAGETLGIVGESGSGKSQTafalMGLLaaNGVI---GGSAKFNGREILNLPEHELNKlr 102
Cdd:cd03295    5 NVTKRYGGGK-KAVNNLNLEIAKGEFLVLIGPSGSGKTTT----MKMI--NRLIeptSGEIFIDGEDIREQDPVELRR-- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 103 aeQISMIFQDpmTSLNPYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEARKRMRmFPHEFSGGMRQRVMIAMA 182
Cdd:cd03295   76 --KIGYVIQQ--IGLFPHMTVEENIALVPKL-LKWPKEKIRERADELLALVGLDPAEFADR-YPHELSGGQQQRVGVARA 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 183 LLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAH 262
Cdd:cd03295  150 LAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPAN 229


                 ..
gi 556427173 263 PY 264
Cdd:cd03295  230 DF 231

PhnL

COG4778

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...

17-246

1.06e-33

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];

Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 123.70 E-value: 1.06e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  17 NLLLDVKDLRVTFK--TPDG-DVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAAN-----GVIGGSAKFNGR 88
Cdd:COG4778    2 TTLLEVENLSKTFTlhLQGGkRLPVLDGVSFSVAAGECVALTGPSGAGKS----TLLKCIYGNylpdsGSILVRHDGGWV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  89 EILNLPEHELNKLRAEQISMIFQdpmtSLNPYMRVG--EQLMEVLmLHKGLGKAEAFEESVKMLDAVKMPEarKRMRMFP 166
Cdd:COG4778   78 DLAQASPREILALRRRTIGYVSQ----FLRVIPRVSalDVVAEPL-LERGVDREEARARARELLARLNLPE--RLWDLPP 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 167 HEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:COG4778  151 ATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRVVDVTPFS 229

CydD

COG4988

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...

9-252

1.60e-33

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 129.88 E-value: 1.60e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   9 APQAQQQNNLLLDVKDLRVTFktpDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGR 88
Cdd:COG4988  326 TAPLPAAGPPSIELEDVSFSY---PGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYS---GSILINGV 399

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  89 EILNLPEHELNKlraeQISMIFQDP----MTslnpymrvgeqLMEVLMLhkglGKAEAFEEsvKMLDAVKMPEARKRMRM 164
Cdd:COG4988  400 DLSDLDPASWRR----QIAWVPQNPylfaGT-----------IRENLRL----GRPDASDE--ELEAALEAAGLDEFVAA 458

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 165 FPHEF-----------SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVA 233
Cdd:COG4988  459 LPDGLdtplgeggrglSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITHRLALLA 536

                        250
                 ....*....|....*....
gi 556427173 234 gICDKVLVMYAGRTMEYGK 252
Cdd:COG4988  537 -QADRILVLDDGRIVEQGT 554

ArtP

COG4161

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

34-260

1.69e-33

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 123.58 E-value: 1.69e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGLL--AANGV--IGGSaKFNGREILNlpEHELNKLRaEQISMI 109
Cdd:COG4161   13 GSHQALFDINLECPSGETLVLLGPSGAGKS-SLLRVLNLLetPDSGQlnIAGH-QFDFSQKPS--EKAIRLLR-QKVGMV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 110 FQDpmTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMIAMALLCRPKL 189
Cdd:COG4161   88 FQQ--YNLWPHLTVMENLIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADR---FPLHLSGGQQQRVAIARALMMEPQV 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556427173 190 LIADEPTTALDVTVQAQIMTLLNELKREFNTAIImITHDLGVVAGICDKVLVMYAGRTMEYGKArDVFYQP 260
Cdd:COG4161  163 LLFDEPTAALDPEITAQVVEIIRELSQTGITQVI-VTHEVEFARKVASQVVYMEKGRIIEQGDA-SHFTQP 231

artP

PRK11124

arginine transporter ATP-binding subunit; Provisional

34-260

2.31e-33

arginine transporter ATP-binding subunit; Provisional

Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 123.20 E-value: 2.31e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGLL--AANGV--IGGSaKFNGREILNlpEHELNKLRaEQISMI 109
Cdd:PRK11124  13 GAHQALFDITLDCPQGETLVLLGPSGAGKS-SLLRVLNLLemPRSGTlnIAGN-HFDFSKTPS--DKAIRELR-RNVGMV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 110 FQDpmTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMIAMALLCRPKL 189
Cdd:PRK11124  88 FQQ--YNLWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRLKPYADR---FPLHLSGGQQQRVAIARALMMEPQV 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556427173 190 LIADEPTTALDVTVQAQIMTLLNELKREFNTAIImITHDLGVVAGICDKVLVMYAGRTMEYGKArDVFYQP 260
Cdd:PRK11124 163 LLFDEPTAALDPEITAQIVSIIRELAETGITQVI-VTHEVEVARKTASRVVYMENGHIVEQGDA-SCFTQP 231

drrA

TIGR01188

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...

34-246

3.27e-33

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]

Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 124.42 E-value: 3.27e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEhelnKLRaEQISMIFQDP 113
Cdd:TIGR01188   4 GDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTS---GTARVAGYDVVREPR----KVR-RSIGIVPQYA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  114 mtslnpymRVGEQL--MEVLMLHK---GLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQRVMIAMALLCRPK 188
Cdd:TIGR01188  76 --------SVDEDLtgRENLEMMGrlyGLPKDEAEERAEELLELFELGEAADRP---VGTYSGGMRRRLDIAASLIHQPD 144

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173  189 LLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:TIGR01188 145 VLFLDEPTTGLDPRTRRAIWDYIRALKEE-GVTILLTTHYMEEADKLCDRIAIIDHGR 201

CydC

COG4987

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...

3-255

9.46e-33

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 127.57 E-value: 9.46e-33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   3 IIETATAPQAQQQNNLLLDvkdlRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGS 82
Cdd:COG4987  319 VTEPAEPAPAPGGPSLELE----DVSFRYPGAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQS---GS 391

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  83 AKFNGREILNLPEHELnklrAEQISMIFQDP---MTSL--NpyMRVG------EQLMEVLmlHK-GLGK-AEAFEESvkm 149
Cdd:COG4987  392 ITLGGVDLRDLDEDDL----RRRIAVVPQRPhlfDTTLreN--LRLArpdatdEELWAAL--ERvGLGDwLAALPDG--- 460

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 150 LDAVkMPEARKRmrmfpheFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDL 229
Cdd:COG4987  461 LDTW-LGEGGRR-------LSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALA--GRTVLLITHRL 530

                        250       260
                 ....*....|....*....|....*.
gi 556427173 230 gVVAGICDKVLVMYAGRTMEYGKARD 255
Cdd:COG4987  531 -AGLERMDRILVLEDGRIVEQGTHEE 555

SunT

COG2274

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...

26-251

1.18e-32

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];

Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 128.03 E-value: 1.18e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  26 RVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPeheLNKLRaEQ 105
Cdd:COG2274  478 NVSFRYPGDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTS---GRILIDGIDLRQID---PASLR-RQ 550

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 106 ISMIFQDPM----------TSLNPYMRVgEQLMEVLMLhkglgkAEAFEESVKM---LDAVKMPEARKrmrmfpheFSGG 172
Cdd:COG2274  551 IGVVLQDVFlfsgtireniTLGDPDATD-EEIIEAARL------AGLHDFIEALpmgYDTVVGEGGSN--------LSGG 615

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 173 MRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAgICDKVLVMYAGRTMEYG 251
Cdd:COG2274  616 QRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLK--GRTVIIIAHRLSTIR-LADRIIVLDKGRIVEDG 691

ABC_MetN

TIGR02314

D-methionine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding ...

19-263

1.24e-32

D-methionine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding protein of the D-methionine ABC transporter complex. Known members belong to the Proteobacteria.

Pssm-ID: 131367 [Multi-domain] Cd Length: 343 Bit Score: 124.22 E-value: 1.24e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGLLAANGviGGSAKFNGREILNLPEHEL 98
Cdd:TIGR02314   1 MIKLSNITKVFHQGTKTIQALNNVSLHVPAGQIYGVIGASGAGKS-TLIRCVNLLERPT--SGSVIVDGQDLTTLSNSEL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   99 NKLRaEQISMIFQ--DPMTSLNPYMRVGEQLmEVlmlhKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQR 176
Cdd:TIGR02314  78 TKAR-RQIGMIFQhfNLLSSRTVFGNVALPL-EL----DNTPKDEIKRKVTELLALVGLGDKHDS---YPSNLSGGQKQR 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  177 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:TIGR02314 149 VAIARALASNPKVLLCDEATSALDPATTQSILELLKEINRRLGLTILLITHEMDVVKRICDCVAVISNGELIEQGTVSEI 228


                  ....*..
gi 556427173  257 FYQPAHP 263
Cdd:TIGR02314 229 FSHPKTP 235

ABC_ModC_molybdenum_transporter

cd03297

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...

43-251

5.12e-32

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 118.94 E-value: 5.12e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  43 NFNLRA-----GETLGIVGESGSGKSQTAFALMGLLAANG---VIGGSAKFNGREILNLPEHElnklraEQISMIFQDpm 114
Cdd:cd03297   12 DFTLKIdfdlnEEVTGIFGASGAGKSTLLRCIAGLEKPDGgtiVLNGTVLFDSRKKINLPPQQ------RKIGLVFQQ-- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 115 TSLNPYMRVGEQLMEVLMLHKGLGKAEAFEEsvkMLDAVKMPEARKRmrmFPHEFSGGMRQRVMIAMALLCRPKLLIADE 194
Cdd:cd03297   84 YALFPHLNVRENLAFGLKRKRNREDRISVDE---LLDLLGLDHLLNR---YPAQLSGGEKQRVALARALAAQPELLLLDE 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 195 PTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03297  158 PFSALDRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214

FtsE

TIGR02673

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...

27-246

7.16e-32

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]

Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 118.50 E-value: 7.16e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   27 VTFKTPdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLL-AANGVIGGSAKFNGREILNLPEHELNKLRaEQ 105
Cdd:TIGR02673   7 VSKAYP-GGVAALHDVSLHIRKGEFLFLTGPSGAGKT----TLLKLLyGALTPSRGQVRIAGEDVNRLRGRQLPLLR-RR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  106 ISMIFQDpmTSLNPYMRVGEQL---MEVLmlhkGLGKAEAFEESVKMLDAVKMPEarkRMRMFPHEFSGGMRQRVMIAMA 182
Cdd:TIGR02673  81 IGVVFQD--FRLLPDRTVYENValpLEVR----GKKEREIQRRVGAALRQVGLEH---KADAFPEQLSGGEQQRVAIARA 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556427173  183 LLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:TIGR02673 152 IVNSPPLLLADEPTGNLDPDLSERILDLLKRLNKR-GTTVIVATHDLSLVDRVAHRVIILDDGR 214

cbiO

PRK13635

energy-coupling factor ABC transporter ATP-binding protein;

19-268

7.58e-32

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 120.51 E-value: 7.58e-32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLrvTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLA-ANGVIggsaKFNGREilnLPEHE 97
Cdd:PRK13635   5 IIRVEHI--SFRYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLpEAGTI----TVGGMV---LSEET 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNKLRaEQISMIFQDPMTSLnpymrVGEQLMEVLmlhkglgkaeAF---------EESVKMLDavkmpEARKRMRM--F- 165
Cdd:PRK13635  76 VWDVR-RQVGMVFQNPDNQF-----VGATVQDDV----------AFglenigvprEEMVERVD-----QALRQVGMedFl 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 166 ---PHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGiCDKVLVM 242
Cdd:PRK13635 135 nrePHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVM 213

                        250       260
                 ....*....|....*....|....*.
gi 556427173 243 YAGRTMEYGKARDVFYQPAHPYSIGL 268
Cdd:PRK13635 214 NKGEILEEGTPEEIFKSGHMLQEIGL 239

3a0106s01

TIGR00968

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]

34-275

1.96e-31

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]

Pssm-ID: 130041 [Multi-domain] Cd Length: 237 Bit Score: 118.36 E-value: 1.96e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPehelnkLRAEQISMIFQDp 113
Cdd:TIGR00968  11 GSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDS---GRIRLNGQDATRVH------ARDRKIGFVFQH- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  114 mTSLNPYMRVGEQLMEVLMLHKgLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMIAMALLCRPKLLIAD 193
Cdd:TIGR00968  81 -YALFKHLTVRDNIAFGLEIRK-HPKAKIKARVEELLELVQLEGLGDR---YPNQLSGGQRQRVALARALAVEPQVLLLD 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  194 EPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPYSIGLLNAVP 273
Cdd:TIGR00968 156 EPFGALDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFLGEVN 235


                  ..
gi 556427173  274 RL 275
Cdd:TIGR00968 236 VL 237

ModC

COG4148

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...

24-296

4.06e-31

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis

Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 120.21 E-value: 4.06e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  24 DLRVTFKTPDGDVTAvndlnfnlragetlgIVGESGSGKSQTAFALMGLL-AANG--VIGGSAKFNGREILNLPEHElnk 100
Cdd:COG4148   15 TLDVDFTLPGRGVTA---------------LFGPSGSGKTTLLRAIAGLErPDSGriRLGGEVLQDSARGIFLPPHR--- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 101 lRaeQISMIFQDPmtSLNPYMRVGEQLMEvlmlhkGLGKAEAFEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQRVMIA 180
Cdd:COG4148   77 -R--RIGYVFQEA--RLFPHLSVRGNLLY------GRKRAPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 181 MALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQP 260
Cdd:COG4148  146 RALLSSPRLLLMDEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRP 225

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 556427173 261 AHPYSIGLLNAVPRLDAE--------GESLLTIPGNPpnlLRLP 296
Cdd:COG4148  226 DLLPLAGGEEAGSVLEATvaahdpdyGLTRLALGGGR---LWVP 266

PhnT2

TIGR03265

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...

34-264

5.18e-31

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 119.76 E-value: 5.18e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEhelnklRAEQISMIFQDp 113
Cdd:TIGR03265  15 GAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTA---GTIYQGGRDITRLPP------QKRDYGIVFQS- 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  114 mTSLNPYMRVgEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMIAMALLCRPKLLIAD 193
Cdd:TIGR03265  85 -YALFPNLTV-ADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERK---YPGQLSGGQQQRVALARALATSPGLLLLD 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556427173  194 EPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPY 264
Cdd:TIGR03265 160 EPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPF 230

ABC_Carb_Monos_II

cd03215

Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...

19-246

5.95e-31

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 115.22 E-value: 5.95e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTfktpdgdvTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHEL 98
Cdd:cd03215    4 VLEVRGLSVK--------GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPAS---GEITLDGKPVTRRSPRDA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRaeqISMIFQDPM-TSLNPYMRVGEQLMevlmlhkglgkaeafeesvkmldavkmpearkrmrmFPHEFSGGMRQRV 177
Cdd:cd03215   73 IRAG---IAYVPEDRKrEGLVLDLSVAENIA------------------------------------LSSLLSGGNQQKV 113

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:cd03215  114 VLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADA-GKAVLLISSELDELLGLCDRILVMYEGR 181

MalK

COG3839

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...

20-264

9.38e-31

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];

Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 119.02 E-value: 9.38e-31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELN 99
Cdd:COG3839    4 LELENVSKSY----GGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTS---GEILIGGRDVTDLPPKDRN 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 klraeqISMIFQDPMtsLNPYMRVGEQL---MEVlmlhKGLGKAEAfEESVK-MLDAVKMPE--ARKrmrmfPHEFSGGM 173
Cdd:COG3839   77 ------IAMVFQSYA--LYPHMTVYENIafpLKL----RKVPKAEI-DRRVReAAELLGLEDllDRK-----PKQLSGGQ 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 174 RQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHD------LGvvagicDKVLVMYAGRT 247
Cdd:COG3839  139 RQRVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDqveamtLA------DRIAVMNDGRI 212

                        250
                 ....*....|....*..
gi 556427173 248 MEYGKARDVFYQPAHPY 264
Cdd:COG3839  213 QQVGTPEELYDRPANLF 229

ABC_CysA_sulfate_importer

cd03296

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...

22-269

1.10e-30

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 116.28 E-value: 1.10e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  22 VKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPehelnkL 101
Cdd:cd03296    5 VRNVSKRF----GDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDS---GTILFGGEDATDVP------V 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 102 RAEQISMIFQDpmTSLNPYMRVGEQL---MEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVM 178
Cdd:cd03296   72 QERNVGFVFQH--YALFRHMTVFDNVafgLRVKPRSERPPEAEIRAKVHELLKLVQLDWLADR---YPAQLSGGQRQRVA 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFY 258
Cdd:cd03296  147 LARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYD 226

                        250
                 ....*....|.
gi 556427173 259 QPAHPYSIGLL 269
Cdd:cd03296  227 HPASPFVYSFL 237

oligo_HPY

TIGR01727

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model ...

249-331

2.25e-30

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model represents a domain found in the C-terminal regions of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid. [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 213647 [Multi-domain] Cd Length: 87 Bit Score: 110.53 E-value: 2.25e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  249 EYGKARDVFYQPAHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEICNS-APPLEEFAPGRLR 327
Cdd:TIGR01727   4 ETGPAEEIFKNPLHPYTKALLSAIPTIKKRDRKLISIPGEVPSLINLPSGCRFYPRCPYAQDECRKePPALVEIAEGHRV 83


                  ....
gi 556427173  328 ACFK 331
Cdd:TIGR01727  84 ACHL 87

ABC_cobalt_CbiO_domain2

cd03226

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...

26-245

5.00e-30

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 113.51 E-value: 5.00e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  26 RVTFKTPDGdVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNlpehelnKLRAEQ 105
Cdd:cd03226    4 NISFSYKKG-TEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESS---GSILLNGKPIKA-------KERRKS 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 106 ISMIFQDPMTSLnpYMR-VGEQLMEVLM-LHKGLGKAEafeESVKMLDAVKMPEARkrmrmfPHEFSGGMRQRVMIAMAL 183
Cdd:cd03226   73 IGYVMQDVDYQL--FTDsVREELLLGLKeLDAGNEQAE---TVLKDLDLYALKERH------PLSLSGGQKQRLAIAAAL 141

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556427173 184 LCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAG 245
Cdd:cd03226  142 LSGKDLLIFDEPTSGLDYKNMERVGELIRELAAQ-GKAVIVITHDYEFLAKVCDRVLLLANG 202

ABCC_MRP_domain2

cd03244

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...

27-251

7.63e-30

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 113.36 E-value: 7.63e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREILNLPeheLNKLRaEQI 106
Cdd:cd03244    8 VSLRYRPNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVEL---SSGSILIDGVDISKIG---LHDLR-SRI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 107 SMIFQDPMT-------SLNPYMRVG-EQLMEVLmlhkglgkaeafeESVKMLDAVKMPEARKRMRMfpHE----FSGGMR 174
Cdd:cd03244   81 SIIPQDPVLfsgtirsNLDPFGEYSdEELWQAL-------------ERVGLKEFVESLPGGLDTVV--EEggenLSVGQR 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 175 QRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNElkrEF-NTAIIMITHDLGVVAGiCDKVLVMYAGRTMEYG 251
Cdd:cd03244  146 QLLCLARALLRKSKILVLDEATASVDPETDALIQKTIRE---AFkDCTVLTIAHRLDTIID-SDRILVLDKGRVVEFD 219

PRK14239

phosphate transporter ATP-binding protein; Provisional

19-262

8.91e-30

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 114.10 E-value: 8.91e-30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFAL--MGLLAANGVIGGSAKFNGREILNlPEH 96
Cdd:PRK14239   5 ILQVSDLSVYY----NKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNDLNPEVTITGSIVYNGHNIYS-PRT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  97 ELNKLRAEqISMIFQDPmtslNPY-MRVGEQLMEVLMLHKGLGKA---EAFEESVKmlDAVKMPEARKRMRMFPHEFSGG 172
Cdd:PRK14239  80 DTVDLRKE-IGMVFQQP----NPFpMSIYENVVYGLRLKGIKDKQvldEAVEKSLK--GASIWDEVKDRLHDSALGLSGG 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 173 MRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFntAIIMITHDLGVVAGICDKVLVMYAGRTMEYGK 252
Cdd:PRK14239 153 QQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDY--TMLLVTRSMQQASRISDRTGFFLDGDLIEYND 230

                        250
                 ....*....|
gi 556427173 253 ARDVFYQPAH 262
Cdd:PRK14239 231 TKQMFMNPKH 240

PRK14247

phosphate ABC transporter ATP-binding protein; Provisional

20-262

1.52e-29

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 113.47 E-value: 1.52e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGL--LAANGVIGGSAKFNGREILNLPEHE 97
Cdd:PRK14247   4 IEIRDLKVSF----GQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLieLYPEARVSGEVYLDGQDIFKMDVIE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNKlraeQISMIFQDPmtSLNPYMRVGEQLMEVLMLHKGL-GKAEAFEESVKMLDAVKM-PEARKRMRMFPHEFSGGMRQ 175
Cdd:PRK14247  80 LRR----RVQMVFQIP--NPIPNLSIFENVALGLKLNRLVkSKKELQERVRWALEKAQLwDEVKDRLDAPAGKLSGGQQQ 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 176 RVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFntAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARD 255
Cdd:PRK14247 154 RLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKDM--TIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTRE 231


                 ....*..
gi 556427173 256 VFYQPAH 262
Cdd:PRK14247 232 VFTNPRH 238

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

4-246

2.98e-29

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 117.04 E-value: 2.98e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   4 IETATAPQAQQQNNLLLDVKDLRVTfktpdgdvTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSA 83
Cdd:COG1129  241 LEDLFPKRAAAPGEVVLEVEGLSVG--------GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPA---DSGEI 309

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  84 KFNGREILN-------------LPEHelnklRAEQ-----------ISMifqdpmTSLNPYMRVGeqlmevlMLHKGLGK 139
Cdd:COG1129  310 RLDGKPVRIrsprdairagiayVPED-----RKGEglvldlsirenITL------ASLDRLSRGG-------LLDRRRER 371

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 140 AEAfEESVKMLDaVKMPEARKRMRmfphEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfN 219
Cdd:COG1129  372 ALA-EEYIKRLR-IKTPSPEQPVG----NLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAE-G 444

                        250       260
                 ....*....|....*....|....*..
gi 556427173 220 TAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:COG1129  445 KAVIVISSELPELLGLSDRILVMREGR 471

PhnK

COG1101

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

20-246

3.91e-29

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 112.49 E-value: 3.91e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFK--TPDgDVTAVNDLNFNLRAGETLGIVGESGSGKSqTafaLMGLLAanGVI---GGSAKFNGREILNLP 94
Cdd:COG1101    2 LELKNLSKTFNpgTVN-EKRALDGLNLTIEEGDFVTVIGSNGAGKS-T---LLNAIA--GSLppdSGSILIDGKDVTKLP 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  95 EHElnklRAEQISMIFQDPMTSLNPYMRVGEQLM------EVLMLHKGLGKA--EAFEESVKMLDavkMP-EARKRMRMf 165
Cdd:COG1101   75 EYK----RAKYIGRVFQDPMMGTAPSMTIEENLAlayrrgKRRGLRRGLTKKrrELFRELLATLG---LGlENRLDTKV- 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 166 pHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITH------DLGvvagicDKV 239
Cdd:COG1101  147 -GLLSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHnmeqalDYG------NRL 219


                 ....*..
gi 556427173 240 LVMYAGR 246
Cdd:COG1101  220 IMMHEGR 226

MdlB

COG1132

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

27-251

6.56e-29

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 116.80 E-value: 6.56e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFkTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFAL-MGLLAANGvigGSAKFNGREILNLPeheLNKLRaEQ 105
Cdd:COG1132  345 VSF-SYPGDRPVLKDISLTIPPGETVALVGPSGSGKS-TLVNLlLRFYDPTS---GRILIDGVDIRDLT---LESLR-RQ 415

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 106 ISMIFQDP----MTslnpymrVGEQLmevlmlhkGLGKAEAFEESVKmlDAVKMPEARKRMRMFPH-----------EFS 170
Cdd:COG1132  416 IGVVPQDTflfsGT-------IRENI--------RYGRPDATDEEVE--EAAKAAQAHEFIEALPDgydtvvgergvNLS 478

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAGiCDKVLVMYAGRTMEY 250
Cdd:COG1132  479 GGQRQRIAIARALLKDPPILILDEATSALDTETEALIQEALERLMK--GRTTIVIAHRLSTIRN-ADRILVLDDGRIVEQ 555


                 .
gi 556427173 251 G 251
Cdd:COG1132  556 G 556

CP_lyasePhnL

TIGR02324

phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P ...

19-242

7.56e-29

phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated C-P lysase complex. This protein (PhnL) and the adjacent-encoded PhnK (TIGR02323) resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this C-P lyase complex rather than part of a transporter per se.

Pssm-ID: 131377 [Multi-domain] Cd Length: 224 Bit Score: 110.94 E-value: 7.56e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   19 LLDVKDLRVTFKTPD-GDV--TAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMG-LLAANGVIGGSAKFNGREILNLP 94
Cdd:TIGR02324   1 LLEVEDLSKTFTLHQqGGVrlPVLKNVSLTVNAGECVALSGPSGAGKSTLLKSLYAnYLPDSGRILVRHEGAWVDLAQAS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   95 EHELNKLRAEQISMIFQdpmtslnpYMRVGEQL--MEVLM---LHKGLGKAEAFEESVKMLDAVKMPEarKRMRMFPHEF 169
Cdd:TIGR02324  81 PREVLEVRRKTIGYVSQ--------FLRVIPRVsaLEVVAeplLERGVPREAARARARELLARLNIPE--RLWHLPPATF 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173  170 SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVM 242
Cdd:TIGR02324 151 SGGEQQRVNIARGFIADYPILLLDEPTASLDAANRQVVVELIAEAKAR-GAALIGIFHDEEVRELVADRVMDV 222

CcmA

COG4133

ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...

19-228

8.06e-29

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 110.26 E-value: 8.06e-29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAF-ALMGLLAANGvigGSAKFNGREILNLPEHe 97
Cdd:COG4133    2 MLEAENLSCRR----GERLLFSGLSFTLAAGEALALTGPNGSGKT-TLLrILAGLLPPSA---GEVLWNGEPIRDARED- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 lnklRAEQISMIFQDPMtsLNPYMRVGEQLMEVLMLHKGLGKAEAFEEsvkMLDAVKMPEARKRmrmFPHEFSGGMRQRV 177
Cdd:COG4133   73 ----YRRRLAYLGHADG--LKPELTVRENLRFWAALYGLRADREAIDE---ALEAVGLAGLADL---PVRQLSAGQKRRV 140

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHD 228
Cdd:COG4133  141 ALARLLLSPAPLWLLDEPFTALDAAGVALLAELIAAHLAR-GGAVLLTTHQ 190

oligo_HPY

pfam08352

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found ...

248-312

1.11e-28

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found towards the C-terminus of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid.

Pssm-ID: 400588 [Multi-domain] Cd Length: 65 Bit Score: 105.56 E-value: 1.11e-28

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173  248 MEYGKARDVFYQPAHPYSIGLLNAVPRLDAEGESLLTIPGNPPNLLRLPKGCPFQPRCPHAMEIC 312
Cdd:pfam08352   1 VEEGPTDDILENPLHPYTRALLNSVPRLDPPKRPLYTIPGNVPSLLELPEGCPFAPRCPFATEEC 65

ABC_MalK_N

cd03301

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...

34-251

1.15e-28

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.

Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 110.04 E-value: 1.15e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLlaaNGVIGGSAKFNGREILNLPEHELNklraeqISMIFQDp 113
Cdd:cd03301   11 GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGL---EEPTSGRIYIGGRDVTDLPPKDRD------IAMVFQN- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 mTSLNPYMRVGEQLMEVLMLHKGlgKAEAFEESVKmlDAVKMPEARKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIAD 193
Cdd:cd03301   81 -YALYPHMTVYDNIAFGLKLRKV--PKDEIDERVR--EVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 194 EPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03301  156 EPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213

modC_ABC

TIGR02142

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...

41-264

1.42e-28

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]

Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 113.28 E-value: 1.42e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   41 DLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANG---VIGGSAKFNGREILNLPEHElnklRAeqISMIFQDpmTSL 117
Cdd:TIGR02142  15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEgeiVLNGRTLFDSRKGIFLPPEK----RR--IGYVFQE--ARL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  118 NPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMpearkrMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTT 197
Cdd:TIGR02142  87 FPHLSVRGNLRYGMKRARPSERRISFERVIELLGIGHL------LGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLA 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173  198 ALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPY 264
Cdd:TIGR02142 161 ALDDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPW 227

cbiO

PRK13650

energy-coupling factor transporter ATPase;

19-268

1.96e-28

energy-coupling factor transporter ATPase;

Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 111.36 E-value: 1.96e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLrvTFK-TPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREilnLPEHE 97
Cdd:PRK13650   4 IIEVKNL--TFKyKEDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAES---GQIIIDGDL---LTEEN 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNKLRaEQISMIFQDPMTSLnpymrVG---EQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMR 174
Cdd:PRK13650  76 VWDIR-HKIGMVFQNPDNQF-----VGatvEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKERE---PARLSGGQK 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 175 QRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAgICDKVLVMYAGRTMEYGKAR 254
Cdd:PRK13650 147 QRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEVA-LSDRVLVMKNGQVESTSTPR 225

                        250
                 ....*....|....
gi 556427173 255 DVFYQPAHPYSIGL 268
Cdd:PRK13650 226 ELFSRGNDLLQLGL 239

cbiO

PRK13637

energy-coupling factor transporter ATPase;

38-275

2.60e-28

energy-coupling factor transporter ATPase;

Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 110.91 E-value: 2.60e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  38 AVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNlPEHELNKLRaEQISMIFQDPMTSL 117
Cdd:PRK13637  22 ALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTS---GKIIIDGVDITD-KKVKLSDIR-KKVGLVFQYPEYQL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 118 npYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMP-EARKRMRmfPHEFSGGMRQRVMIAMALLCRPKLLIADEPT 196
Cdd:PRK13637  97 --FEETIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLDyEDYKDKS--PFELSGGQKRRVAIAGVVAMEPKILILDEPT 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 197 TALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPYSIGLlnAVPRL 275
Cdd:PRK13637 173 AGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKEVETLESIGL--AVPQV 249

cbiO

PRK13642

energy-coupling factor transporter ATPase;

17-268

8.67e-28

energy-coupling factor transporter ATPase;

Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 109.41 E-value: 8.67e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  17 NLLLDVKDLRVTFKTpDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREilnLPEH 96
Cdd:PRK13642   2 NKILEVENLVFKYEK-ESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEE---FEGKVKIDGEL---LTAE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  97 ELNKLRaEQISMIFQDPMTSLnpymrVGEQLMEVL---MLHKGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGM 173
Cdd:PRK13642  75 NVWNLR-RKIGMVFQNPDNQF-----VGATVEDDVafgMENQGIPREEMIKRVDEALLAVNMLDFKTRE---PARLSGGQ 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 174 RQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGiCDKVLVMYAGRTMEYGKA 253
Cdd:PRK13642 146 KQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAP 224

                        250
                 ....*....|....*
gi 556427173 254 RDVFYQPAHPYSIGL 268
Cdd:PRK13642 225 SELFATSEDMVEIGL 239

ABC_BcrA_bacitracin_resist

cd03268

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...

20-251

9.17e-28

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.

Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 107.69 E-value: 9.17e-28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNlpehelN 99
Cdd:cd03268    1 LKTNDLTKTY----GKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDS---GEITFDGKSYQK------N 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRAEQISMIFQDPmtSLNPYMRVGEQLmEVLMLHKGLGKAEAFEesvkMLDAVKMPE-ARKRMRmfphEFSGGMRQRVM 178
Cdd:cd03268   68 IEALRRIGALIEAP--GFYPNLTARENL-RLLARLLGIRKKRIDE----VLDVVGLKDsAKKKVK----GFSLGMKQRLG 136

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELkREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03268  137 IALALLGNPDLLILDEPTNGLDPDGIKELRELILSL-RDQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208

ABC_NatA_sodium_exporter

cd03266

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...

19-251

1.02e-27

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.

Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 107.84 E-value: 1.02e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPehel 98
Cdd:cd03266    1 MITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDA---GFATVDGFDVVKEP---- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 nklRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHkGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQRVM 178
Cdd:cd03266   74 ---AEARRRLGFVSDSTGLYDRLTARENLEYFAGLY-GLKGDELTARLEELADRLGMEELLDRR---VGGFSTGMRQKVA 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03266  147 IARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRAL-GKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218

ABC_TM1139_LivF_branched

cd03224

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...

20-256

1.19e-27

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.

Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 107.52 E-value: 1.19e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAangVIGGSAKFNGREILNLPEHELN 99
Cdd:cd03224    1 LEVENLNAGY----GKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLP---PRSGSIRFDGRDITGLPPHERA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLraeQISMIFQDPMtsLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKmpEARKRMrmfPHEFSGGMRQRVMI 179
Cdd:cd03224   74 RA---GIGYVPEGRR--IFPELTVEENLLLGAYARRRAKRKARLERVYELFPRLK--ERRKQL---AGTLSGGEQQMLAI 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 180 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:cd03224  144 ARALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

19-256

1.25e-27

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 112.43 E-value: 1.25e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTfktPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANgviGGSAKFNGREILNLPEHEl 98
Cdd:COG3845  257 VLEVENLSVR---DDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPA---SGSIRLDGEDITGLSPRE- 329

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 nkLRAEQISMIFQDPM-TSLNPYMRVGEQLmeVLMLH-------KGL---GKAEAF-EESVKMLDaVKMPEARKRMRMfp 166
Cdd:COG3845  330 --RRRLGVAYIPEDRLgRGLVPDMSVAENL--ILGRYrrppfsrGGFldrKAIRAFaEELIEEFD-VRTPGPDTPARS-- 402

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 167 heFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:COG3845  403 --LSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDA-GAAVLLISEDLDEILALSDRIAVMYEGR 479

                        250
                 ....*....|
gi 556427173 247 TMEYGKARDV 256
Cdd:COG3845  480 IVGEVPAAEA 489

glnQ

PRK09493

glutamine ABC transporter ATP-binding protein GlnQ;

34-263

1.60e-27

glutamine ABC transporter ATP-binding protein GlnQ;

Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 107.87 E-value: 1.60e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAANGVI-GGSAKFNGREILNlPEHELNKLRAEQiSMIFQD 112
Cdd:PRK09493  12 GPTQVLHNIDLNIDQGEVVVIIGPSGSGKS----TLLRCINKLEEItSGDLIVDGLKVND-PKVDERLIRQEA-GMVFQQ 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 113 pmTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEarkRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIA 192
Cdd:PRK09493  86 --FYLFPHLTALENVMFGPLRVRGASKEEAEKQARELLAKVGLAE---RAHHYPSELSGGQQQRVAIARALAVKPKLMLF 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556427173 193 DEPTTALDVTVQAQIMTLLNELKREFNTAIImITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHP 263
Cdd:PRK09493 161 DEPTSALDPELRHEVLKVMQDLAEEGMTMVI-VTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQ 230

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

19-256

2.76e-27

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 111.65 E-value: 2.76e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTafaLMGLLAanGVI---GGSAKFNGREIlnlpe 95
Cdd:COG1129    4 LLEMRGISKSF----GGVKALDGVSLELRPGEVHALLGENGAGKS-T---LMKILS--GVYqpdSGEILLDGEPV----- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  96 HELNKLRAEQ--ISMIFQDPmtSLNPYMRVGEQL-MEVLMLHKGL-GKAEAFEESVKMLDAVKMPE-ARKRMRmfphEFS 170
Cdd:COG1129   69 RFRSPRDAQAagIAIIHQEL--NLVPNLSVAENIfLGREPRRGGLiDWRAMRRRARELLARLGLDIdPDTPVG----DLS 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEY 250
Cdd:COG1129  143 VAQQQLVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQ-GVAIIYISHRLDEVFEIADRVTVLRDGRLVGT 221


                 ....*.
gi 556427173 251 GKARDV 256
Cdd:COG1129  222 GPVAEL 227

cbiO

PRK13648

cobalt transporter ATP-binding subunit; Provisional

16-268

2.80e-27

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 107.91 E-value: 2.80e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  16 NNLLLDVKDlrVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNlpe 95
Cdd:PRK13648   4 KNSIIVFKN--VSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKS---GEIFYNNQAITD--- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  96 HELNKLRaEQISMIFQDP----MTSLNPYmRVGEQLMEVLMLHKGLGK--AEAFEEsVKMLDavkmpearkRMRMFPHEF 169
Cdd:PRK13648  76 DNFEKLR-KHIGIVFQNPdnqfVGSIVKY-DVAFGLENHAVPYDEMHRrvSEALKQ-VDMLE---------RADYEPNAL 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 170 SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGiCDKVLVMYAGRTME 249
Cdd:PRK13648 144 SGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYK 222

                        250
                 ....*....|....*....
gi 556427173 250 YGKARDVFYQPAHPYSIGL 268
Cdd:PRK13648 223 EGTPTEIFDHAEELTRIGL 241

ABC_FtsE

cd03292

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...

30-246

3.86e-27

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages

Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 105.95 E-value: 3.86e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  30 KTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAANGV-IGGSAKFNGREILNLPEHELNKLRaEQISM 108
Cdd:cd03292    8 KTYPNGTAALDGINISISAGEFVFLVGPSGAGKS----TLLKLIYKEELpTSGTIRVNGQDVSDLRGRAIPYLR-RKIGV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 109 IFQDpmTSLNPYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMpeaRKRMRMFPHEFSGGMRQRVMIAMALLCRPK 188
Cdd:cd03292   83 VFQD--FRLLPDRNVYENVAFALEV-TGVPPREIRKRVPAALELVGL---SHKHRALPAELSGGEQQRVAIARAIVNSPT 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 189 LLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:cd03292  157 ILIADEPTGNLDPDTTWEIMNLLKKINKA-GTTVVVATHAKELVDTTRHRVIALERGK 213

PstB

COG1117

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...

20-263

3.90e-27

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 107.04 E-value: 3.90e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqT---AFALMGLLAANGVIGGSAKFNGREILNlPEH 96
Cdd:COG1117   12 IEVRNLNVYY----GDKQALKDINLDIPENKVTALIGPSGCGKS-TllrCLNRMNDLIPGARVEGEILLDGEDIYD-PDV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  97 ELNKLRAeQISMIFQDPmtslNPY-MRVGEQLMEVLMLHKGLGKA---EAFEESVKML---DAVKmpearKRMRMFPHEF 169
Cdd:COG1117   86 DVVELRR-RVGMVFQKP----NPFpKSIYDNVAYGLRLHGIKSKSeldEIVEESLRKAalwDEVK-----DRLKKSALGL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 170 SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFntAIIMITHDLGVVAGICDKVLVMYAGRTME 249
Cdd:COG1117  156 SGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDY--TIVIVTHNMQQAARVSDYTAFFYLGELVE 233

                        250
                 ....*....|....
gi 556427173 250 YGKARDVFYQPAHP 263
Cdd:COG1117  234 FGPTEQIFTNPKDK 247

PRK10584

putative ABC transporter ATP-binding protein YbbA; Provisional

49-249

4.73e-27

putative ABC transporter ATP-binding protein YbbA; Provisional

Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 106.40 E-value: 4.73e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  49 GETLGIVGESGSGKSqtafALMGLLAanGVIGGSA---KFNGREILNLPEHELNKLRAEQISMIFQDPMtsLNPYMRVGE 125
Cdd:PRK10584  36 GETIALIGESGSGKS----TLLAILA--GLDDGSSgevSLVGQPLHQMDEEARAKLRAKHVGFVFQSFM--LIPTLNALE 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 126 QLmEVLMLHKGLGKAEAFEESVKMLDAVKMPearKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQA 205
Cdd:PRK10584 108 NV-ELPALLRGESSRQSRNGAKALLEQLGLG---KRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGD 183

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 556427173 206 QIMTLLNELKREFNTAIIMITHDLgVVAGICDKVLVMYAGRTME 249
Cdd:PRK10584 184 KIADLLFSLNREHGTTLILVTHDL-QLAARCDRRLRLVNGQLQE 226

cbiO

PRK13639

cobalt transporter ATP-binding subunit; Provisional

19-260

5.23e-27

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 107.47 E-value: 5.23e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRvtFKTPDGDVtAVNDLNFNLRAGETLGIVGESGSGKSqTAFalmglLAANGVI---GGSAKFNGREIlNLPE 95
Cdd:PRK13639   1 ILETRDLK--YSYPDGTE-ALKGINFKAEKGEMVALLGPNGAGKS-TLF-----LHFNGILkptSGEVLIKGEPI-KYDK 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  96 HELNKLRaEQISMIFQDPMTSLnpYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQ 175
Cdd:PRK13639  71 KSLLEVR-KTVGIVFQNPDDQL--FAPTVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKP---PHHLSGGQKK 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 176 RVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARD 255
Cdd:PRK13639 145 RVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGIT-IIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKE 223


                 ....*
gi 556427173 256 VFYQP 260
Cdd:PRK13639 224 VFSDI 228

cbiO

PRK13640

energy-coupling factor transporter ATPase;

27-268

5.58e-27

energy-coupling factor transporter ATPase;

Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 107.58 E-value: 5.58e-27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKFNGreiLNLPEHELNKLRaEQI 106
Cdd:PRK13640  11 VSFTYPDSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPNSKITVDG---ITLTAKTVWDIR-EKV 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 107 SMIFQDPMTSLnpymrVGEQLMEVLML---HKGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQRVMIAMAL 183
Cdd:PRK13640  87 GIVFQNPDNQF-----VGATVGDDVAFgleNRAVPRPEMIKIVRDVLADVGMLDYIDSE---PANLSGGQKQRVAIAGIL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 184 LCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGvVAGICDKVLVMYAGRTMEYGKARDVFYQPAHP 263
Cdd:PRK13640 159 AVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDID-EANMADQVLVLDDGKLLAQGSPVEIFSKVEML 237


                 ....*
gi 556427173 264 YSIGL 268
Cdd:PRK13640 238 KEIGL 242

ABC_Carb_Monos_I

cd03216

First domain of the ATP-binding cassette component of monosaccharide transport system; This ...

20-247

1.20e-26

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 103.28 E-value: 1.20e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLpehelN 99
Cdd:cd03216    1 LELRGITKRF----GGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDS---GEILVDGKEVSFA-----S 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRAEQ--ISMIFQdpmtslnpymrvgeqlmevlmlhkglgkaeafeesvkmldavkmpearkrmrmfpheFSGGMRQRV 177
Cdd:cd03216   69 PRDARRagIAMVYQ---------------------------------------------------------LSVGERQMV 91

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRT 247
Cdd:cd03216   92 EIARALARNARLLILDEPTAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRV 160

PRK10619

histidine ABC transporter ATP-binding protein HisP;

20-263

1.78e-26

histidine ABC transporter ATP-binding protein HisP;

Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 105.44 E-value: 1.78e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGLLAANGviGGSAKFNGREI--------- 90
Cdd:PRK10619   6 LNVIDLHKRY----GEHEVLKGVSLQANAGDVISIIGSSGSGKS-TFLRCINFLEKPS--EGSIVVNGQTInlvrdkdgq 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  91 LNLPEHELNKLRAEQISMIFQDpmTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEaRKRMRmFPHEFS 170
Cdd:PRK10619  79 LKVADKNQLRLLRTRLTMVFQH--FNLWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDE-RAQGK-YPVHLS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEY 250
Cdd:PRK10619 155 GGQQQRVSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKT-MVVVTHEMGFARHVSSHVIFLHQGKIEEE 233

                        250
                 ....*....|...
gi 556427173 251 GKARDVFYQPAHP 263
Cdd:PRK10619 234 GAPEQLFGNPQSP 246

TauB

COG4525

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

20-228

2.61e-26

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 104.94 E-value: 2.61e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNlPEHEln 99
Cdd:COG4525    4 LTVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSS---GEITLDGVPVTG-PGAD-- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 klRAeqisMIFQDpmTSLNPYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMI 179
Cdd:COG4525   78 --RG----VVFQK--DALLPWLNVLDNVAFGLRL-RGVPKAERRARAEELLALVGLADFARR---RIWQLSGGMRQRVGI 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 556427173 180 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHD 228
Cdd:COG4525  146 ARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHS 194

OpuBA

COG1125

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...

26-264

2.73e-26

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 105.94 E-value: 2.73e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  26 RVTfKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTafalmgLLAANGVI---GGSAKFNGREILNLPEHELNKlr 102
Cdd:COG1125    6 NVT-KRYPDGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTT------LRMINRLIeptSGRILIDGEDIRDLDPVELRR-- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 103 aeQISMIFQDpmTSLNPYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEA--RKRmrmFPHEFSGGMRQRVMIA 180
Cdd:COG1125   77 --RIGYVIQQ--IGLFPHMTVAENIATVPRL-LGWDKERIRARVDELLELVGLDPEeyRDR---YPHELSGGQQQRVGVA 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 181 MALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHD------LGvvagicDKVLVMYAGRTMEYGKAR 254
Cdd:COG1125  149 RALAADPPILLMDEPFGALDPITREQLQDELLRLQRELGKTIVFVTHDidealkLG------DRIAVMREGRIVQYDTPE 222

                        250
                 ....*....|
gi 556427173 255 DVFYQPAHPY 264
Cdd:COG1125  223 EILANPANDF 232

YnjD

COG4136

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...

20-228

3.09e-26

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];

Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 103.33 E-value: 3.09e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALM-GLLAANGVIGGSAKFNGREILNLPEHel 98
Cdd:COG4136    2 LSLENLTITL----GGRPLLAPLSLTVAPGEILTLMGPSGSGKS-TLLAAIaGTLSPAFSASGEVLLNGRRLTALPAE-- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 nklrAEQISMIFQDPMtsLNPYMRVGEQLMevLMLHKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVM 178
Cdd:COG4136   75 ----QRRIGILFQDDL--LFPHLSVGENLA--FALPPTIGRAQRRARVEQALEEAGLAGFADR---DPATLSGGQRARVA 143

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHD 228
Cdd:COG4136  144 LLRALLAEPRALLLDEPFSKLDAALRAQFREFVFEQIRQRGIPALLVTHD 193

lolD

PRK11629

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

41-246

3.25e-26

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 104.13 E-value: 3.25e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  41 DLNFNLRAGETLGIVGESGSGKSQTAFALMGLlaaNGVIGGSAKFNGREILNLPEHELNKLRAEQISMIFQdpMTSLNPY 120
Cdd:PRK11629  27 NVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGL---DTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQ--FHHLLPD 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 121 MRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMpEARKRMRmfPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALD 200
Cdd:PRK11629 102 FTALENVAMPLLI-GKKKPAEINSRALEMLAAVGL-EHRANHR--PSELSGGERQRVAIARALVNNPRLVLADEPTGNLD 177

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 556427173 201 VTVQAQIMTLLNELKREFNTAIIMITHDLGvVAGICDKVLVMYAGR 246
Cdd:PRK11629 178 ARNADSIFQLLGELNRLQGTAFLVVTHDLQ-LAKRMSRQLEMRDGR 222

PRK11264

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

20-263

3.30e-26

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 104.45 E-value: 3.30e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFKtpdgDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGLL--AANGVIG-GSAKFNGREILNLPEH 96
Cdd:PRK11264   4 IEVKNLVKKFH----GQTVLHGIDLEVKPGEVVAIIGPSGSGKT-TLLRCINLLeqPEAGTIRvGDITIDTARSLSQQKG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  97 ELNKLRaEQISMIFQDpmTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQR 176
Cdd:PRK11264  79 LIRQLR-QHVGFVFQN--FNLFPHRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETS---YPRRLSGGQQQR 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 177 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIImITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:PRK11264 153 VAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVI-VTHEMSFARDVADRAIFMDQGRIVEQGPAKAL 231


                 ....*..
gi 556427173 257 FYQPAHP 263
Cdd:PRK11264 232 FADPQQP 238

ABC_MTABC3_MDL1_MDL2

cd03249

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...

27-252

3.37e-26

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.

Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 104.16 E-value: 3.37e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFKTPD-GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAfALmgLLAANGVIGGSAKFNGREILNLPeheLNKLRaEQ 105
Cdd:cd03249    6 VSFRYPSrPDVPILKGLSLTIPPGKTVALVGSSGCGKSTVV-SL--LERFYDPTSGEILLDGVDIRDLN---LRWLR-SQ 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 106 ISMIFQDPMTSlnpYMRVGEQLmevlmlhkGLGKAEAFEESVKmlDAVKMPEARKRMRMFPHEF-----------SGGMR 174
Cdd:cd03249   79 IGLVSQEPVLF---DGTIAENI--------RYGKPDATDEEVE--EAAKKANIHDFIMSLPDGYdtlvgergsqlSGGQK 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 175 QRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAGiCDKVLVMYAGRTMEYGK 252
Cdd:cd03249  146 QRIAIARALLRNPKILLLDEATSALDAESEKLVQEALDRAMK--GRTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQGT 220

cbiO

PRK13636

cobalt transporter ATP-binding subunit; Provisional

19-257

3.61e-26

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 105.31 E-value: 3.61e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLrvTFKTPDGdVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREIlNLPEHEL 98
Cdd:PRK13636   5 ILKVEEL--NYNYSDG-THALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKP---SSGRILFDGKPI-DYSRKGL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRaEQISMIFQDP---MTSLNPYMRVGEQLMEVlmlhkGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQ 175
Cdd:PRK13636  78 MKLR-ESVGMVFQDPdnqLFSASVYQDVSFGAVNL-----KLPEDEVRKRVDNALKRTGIEHLKDKP---THCLSFGQKK 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 176 RVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARD 255
Cdd:PRK13636 149 RVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKE 228


                 ..
gi 556427173 256 VF 257
Cdd:PRK13636 229 VF 230

COG4559

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];

19-257

3.77e-26

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 104.43 E-value: 3.77e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHEL 98
Cdd:COG4559    1 MLEAENLSVRL----GGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSS---GEVRLNGRPLAAWSPWEL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRA---EQISMIFqdPMTSLnpymrvgeqlmEVLML----HkGLGKAEAFEESVKMLDAVKMpeARKRMRMFPhEFSG 171
Cdd:COG4559   74 ARRRAvlpQHSSLAF--PFTVE-----------EVVALgrapH-GSSAAQDRQIVREALALVGL--AHLAGRSYQ-TLSG 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 172 GMRQRVMIAMAlLC--------RPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMY 243
Cdd:COG4559  137 GEQQRVQLARV-LAqlwepvdgGPRWLFLDEPTSALDLAHQHAVLRLARQLARR-GGGVVAVLHDLNLAAQYADRILLLH 214

                        250
                 ....*....|....
gi 556427173 244 AGRTMEYGKARDVF 257
Cdd:COG4559  215 QGRLVAQGTPEEVL 228

cbiO

PRK13632

cobalt transporter ATP-binding subunit; Provisional

27-257

5.03e-26

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 104.69 E-value: 5.03e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlnlPEHELNKLRaEQI 106
Cdd:PRK13632  13 VSFSYPNSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQS---GEIKIDGITI---SKENLKEIR-KKI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 107 SMIFQDPMTSLnpymrVGeqlmevlmlhkglGKAE---AFEESVKMLDAVKMP----EARKRMRMF------PHEFSGGM 173
Cdd:PRK13632  86 GIIFQNPDNQF-----IG-------------ATVEddiAFGLENKKVPPKKMKdiidDLAKKVGMEdyldkePQNLSGGQ 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 174 RQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAgICDKVLVMYAGRTMEYGKA 253
Cdd:PRK13632 148 KQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLIAQGKP 226


                 ....
gi 556427173 254 RDVF 257
Cdd:PRK13632 227 KEIL 230

PRK10535

macrolide ABC transporter ATP-binding protein/permease MacB;

19-233

5.22e-26

macrolide ABC transporter ATP-binding protein/permease MacB;

Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 108.66 E-value: 5.22e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAA-NGVIGGSAKFNGREILNLPEHE 97
Cdd:PRK10535   4 LLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKS----TLMNILGClDKPTSGTYRVAGQDVATLDADA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNKLRAEQISMIFQdpMTSLNPYMrVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEarkRMRMFPHEFSGGMRQRV 177
Cdd:PRK10535  80 LAQLRREHFGFIFQ--RYHLLSHL-TAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLED---RVEYQPSQLSGGQQQRV 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIImITHDLGVVA 233
Cdd:PRK10535 154 SIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVII-VTHDPQVAA 208

PRK14267

phosphate ABC transporter ATP-binding protein; Provisional

17-262

5.41e-26

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 104.15 E-value: 5.41e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  17 NLLLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAN--GVIGGSAKFNGREILNlP 94
Cdd:PRK14267   2 KFAIETVNLRVYY----GSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeeARVEGEVRLFGRNIYS-P 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  95 EHELNKLRaEQISMIFQDPmtSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVK--MLDAVKMPEARKRMRMFPHEFSGG 172
Cdd:PRK14267  77 DVDPIEVR-REVGMVFQYP--NPFPHLTIYDNVAIGVKLNGLVKSKKELDERVEwaLKKAALWDEVKDRLNDYPSNLSGG 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 173 MRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFntAIIMITHDLGVVAGICDKVLVMYAGRTMEYGK 252
Cdd:PRK14267 154 QRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKEY--TIVLVTHSPAQAARVSDYVAFLYLGKLIEVGP 231

                        250
                 ....*....|
gi 556427173 253 ARDVFYQPAH 262
Cdd:PRK14267 232 TRKVFENPEH 241

ABCC_ATM1_transporter

cd03253

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...

27-252

5.62e-26

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 103.46 E-value: 5.62e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFKTPDGdVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALmgLLAANGVIGGSAKFNGREILNLpehELNKLRaEQI 106
Cdd:cd03253    6 VTFAYDPG-RPVLKDVSFTIPAGKKVAIVGPSGSGKS-TILRL--LFRFYDVSSGSILIDGQDIREV---TLDSLR-RAI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 107 SMIFQDpmTSL-NpymrvgeqlmEVLMLHKGLGKAEAFEESVkmLDAVKMPEARKRMRMFPHEF-----------SGGMR 174
Cdd:cd03253   78 GVVPQD--TVLfN----------DTIGYNIRYGRPDATDEEV--IEAAKAAQIHDKIMRFPDGYdtivgerglklSGGEK 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 175 QRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAGiCDKVLVMYAGRTMEYGK 252
Cdd:cd03253  144 QRVAIARAILKNPPILLLDEATSALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGT 218

ABC_drug_resistance_like

cd03264

ABC-type multidrug transport system, ATPase component; The biological function of this family ...

20-246

6.08e-26

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 102.66 E-value: 6.08e-26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGeTLGIVGESGSGKSqtafALMGLLAanGVI---GGSAKFNGREILNLPEh 96
Cdd:cd03264    1 LQLENLTKRY----GKKRALDGVSLTLGPG-MYGLLGPNGAGKT----TLMRILA--TLTppsSGTIRIDGQDVLKQPQ- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  97 elnKLRAeQISMIFQDPMTSlnPYMRVGEQL--MEVLmlhKGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMR 174
Cdd:cd03264   69 ---KLRR-RIGYLPQEFGVY--PNFTVREFLdyIAWL---KGIPSKEVKARVDEVLELVNLGDRAKKK---IGSLSGGMR 136

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556427173 175 QRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:cd03264  137 RRVGIAQALVGDPSILIVDEPTAGLDPEERIRFRNLLSELGE--DRIVILSTHIVEDVESLCNQVAVLNKGK 206

COG4586

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

12-252

1.14e-25

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 104.78 E-value: 1.14e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  12 AQQQNNLLLDVKDL-RVTFKTpdgdVTAVNDLNFNLRAGETLGIVGESGSGKSQTafalMGLLAanGVI---GGSAKFNG 87
Cdd:COG4586   14 YEKEPGLKGALKGLfRREYRE----VEAVDDISFTIEPGEIVGFIGPNGAGKSTT----IKMLT--GILvptSGEVRVLG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  88 REilnlPEHELNKLrAEQISMIFqdpmtslnpymrvG--EQL------MEVLMLHK---GLGKAEA---FEESVKMLDA- 152
Cdd:COG4586   84 YV----PFKRRKEF-ARRIGVVF-------------GqrSQLwwdlpaIDSFRLLKaiyRIPDAEYkkrLDELVELLDLg 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 153 --VKMPeARK-----RMRMfphEfsggmrqrvmIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMI 225
Cdd:COG4586  146 elLDTP-VRQlslgqRMRC---E----------LAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLT 211

                        250       260
                 ....*....|....*....|....*..
gi 556427173 226 THDLGVVAGICDKVLVMYAGRTMEYGK 252
Cdd:COG4586  212 SHDMDDIEALCDRVIVIDHGRIIYDGS 238

ThiQ

COG3840

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

42-263

1.68e-25

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 102.14 E-value: 1.68e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  42 LNFNL--RAGETLGIVGESGSGKSqTAFALM-GLLAAngvIGGSAKFNGREILNLPEHElnklRAeqISMIFQDpmTSLN 118
Cdd:COG3840   16 LRFDLtiAAGERVAILGPSGAGKS-TLLNLIaGFLPP---DSGRILWNGQDLTALPPAE----RP--VSMLFQE--NNLF 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 119 PYMRVGEQLmeVLMLHKGLGKAEAFEESVK-MLDAVKMPEARKRMrmfPHEFSGGMRQRVMIAMALLCRPKLLIADEPTT 197
Cdd:COG3840   84 PHLTVAQNI--GLGLRPGLKLTAEQRAQVEqALERVGLAGLLDRL---PGQLSGGQRQRVALARCLVRKRPILLLDEPFS 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556427173 198 ALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHP 263
Cdd:COG3840  159 ALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPP 224

PRK13633

energy-coupling factor transporter ATPase;

27-268

1.73e-25

energy-coupling factor transporter ATPase;

Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 103.24 E-value: 1.73e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFKTPDGD----VTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNlpEHELNKLR 102
Cdd:PRK13633  10 VSYKYESNEesteKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSE---GKVYVDGLDTSD--EENLWDIR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 103 aEQISMIFQDPMTSLNPYMrVGEqlmEVLMLHKGLG-KAEAFEESV-KMLDAVKMPEARKRMrmfPHEFSGGMRQRVMIA 180
Cdd:PRK13633  85 -NKAGMVFQNPDNQIVATI-VEE---DVAFGPENLGiPPEEIRERVdESLKKVGMYEYRRHA---PHLLSGGQKQRVAIA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 181 MALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGiCDKVLVMYAGRTMEYGKARDVFYQP 260
Cdd:PRK13633 157 GILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIFKEV 235


                 ....*...
gi 556427173 261 AHPYSIGL 268
Cdd:PRK13633 236 EMMKKIGL 243

potG

PRK11607

putrescine ABC transporter ATP-binding subunit PotG;

10-270

1.89e-25

putrescine ABC transporter ATP-binding subunit PotG;

Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 104.92 E-value: 1.89e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  10 PQAQQQNNL--LLDVKDLRVTFktpDGDvTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAA-NGVIGGSAKFN 86
Cdd:PRK11607   8 PQAKTRKALtpLLEIRNLTKSF---DGQ-HAVDDVSLTIYKGEIFALLGASGCGKS----TLLRMLAGfEQPTAGQIMLD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  87 GREILNLPEHElnklraEQISMIFQDpmTSLNPYMRVgEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMrmfP 166
Cdd:PRK11607  80 GVDLSHVPPYQ------RPINMMFQS--YALFPHMTV-EQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRK---P 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 167 HEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PRK11607 148 HQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGK 227

                        250       260
                 ....*....|....*....|....*..
gi 556427173 247 TMEYGKARDVFYQPAHPYS---IGLLN 270
Cdd:PRK11607 228 FVQIGEPEEIYEHPTTRYSaefIGSVN 254

hmuV

PRK13548

hemin importer ATP-binding subunit; Provisional

19-257

3.05e-25

hemin importer ATP-binding subunit; Provisional

Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 102.16 E-value: 3.05e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREILNLPEHEL 98
Cdd:PRK13548   2 MLEARNLSVRL----GGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSP---DSGEVRLNGRPLADWSPAEL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRA---EQISMIFqdpmtslnPYmRVGEQlmeVLM--LHKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGM 173
Cdd:PRK13548  75 ARRRAvlpQHSSLSF--------PF-TVEEV---VAMgrAPHGLSRAEDDALVAAALAQVDLAHLAGR---DYPQLSGGE 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 174 RQRVMIAMALL------CRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRT 247
Cdd:PRK13548 140 QQRVQLARVLAqlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRL 219

                        250
                 ....*....|
gi 556427173 248 MEYGKARDVF 257
Cdd:PRK13548 220 VADGTPAEVL 229

cbiO

PRK13647

cobalt transporter ATP-binding subunit; Provisional

17-251

3.33e-25

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 102.51 E-value: 3.33e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  17 NLLLDVKDLrvTFKTPDGDvTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLlaaNGVIGGSAKFNGREILNLPEH 96
Cdd:PRK13647   2 DNIIEVEDL--HFRYKDGT-KALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGI---YLPQRGRVKVMGREVNAENEK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  97 ELNKlraeQISMIFQDP---MTSLNPYMRV--GEQLMevlmlhkGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSG 171
Cdd:PRK13647  76 WVRS----KVGLVFQDPddqVFSSTVWDDVafGPVNM-------GLDKDEVERRVEEALKAVRMWDFRDKP---PYHLSY 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 172 GMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:PRK13647 142 GQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQGKT-VIVATHDVDLAAEWADQVIVLKEGRVLAEG 220

potA

TIGR01187

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...

54-277

4.36e-25

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 102.96 E-value: 4.36e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   54 IVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHelnkLRAeqISMIFQDpmTSLNPYMRVGEQLMEVLML 133
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDS---GSIMLDGEDVTNVPPH----LRH--INMVFQS--YALFPHMTVEENVAFGLKM 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  134 hKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNE 213
Cdd:TIGR01187  70 -RKVPRAEIKPRVLEALRLVQLEEFADR---KPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKT 145

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556427173  214 LKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPYSIGLLNAVPRLDA 277
Cdd:TIGR01187 146 IQEQLGITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEA 209

ProV

COG4175

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...

34-264

5.96e-25

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 103.64 E-value: 5.96e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSqTafalmgLL-AANGVI---GGSAKFNGREILNLPEHELNKLRAEQISMI 109
Cdd:COG4175   38 GQTVGVNDASFDVEEGEIFVIMGLSGSGKS-T------LVrCLNRLIeptAGEVLIDGEDITKLSKKELRELRRKKMSMV 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 110 FQdpmtS--LNPYMRVGEQL---MEVlmlhKGLGKAEAFEESVKMLDAV--KMPEARkrmrmFPHEFSGGMRQRVMIAMA 182
Cdd:COG4175  111 FQ----HfaLLPHRTVLENVafgLEI----QGVPKAERRERAREALELVglAGWEDS-----YPDELSGGMQQRVGLARA 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 183 LLCRPKLLIADEPTTALD----VTVQAQIMTLLNELKRefnTaIIMITHDL------GvvagicDKVLVMYAGRTMEYGK 252
Cdd:COG4175  178 LATDPDILLMDEAFSALDplirREMQDELLELQAKLKK---T-IVFITHDLdealrlG------DRIAIMKDGRIVQIGT 247

                        250
                 ....*....|..
gi 556427173 253 ARDVFYQPAHPY 264
Cdd:COG4175  248 PEEILTNPANDY 259

ABC_NatA_like

cd03267

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...

25-248

8.39e-25

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.

Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 100.48 E-value: 8.39e-25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  25 LRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGreilNLPEHELNKLRAe 104
Cdd:cd03267   23 LKSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTS---GEVRVAG----LVPWKRRKKFLR- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 105 QISMIFQDPmtslnpymrvgEQL------MEVLMLHK---GLGKAEA---FEESVKMLDAVKMPEARKRmrmfphEFSGG 172
Cdd:cd03267   95 RIGVVFGQK-----------TQLwwdlpvIDSFYLLAaiyDLPPARFkkrLDELSELLDLEELLDTPVR------QLSLG 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556427173 173 MRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTM 248
Cdd:cd03267  158 QRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLL 233

ABCC_NFT1

cd03369

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...

20-251

2.23e-24

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 98.64 E-value: 2.23e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFkTPDGDvTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREILNLPeheLN 99
Cdd:cd03369    7 IEVENLSVRY-APDLP-PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEA---EEGKIEIDGIDISTIP---LE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRaEQISMIFQDPM-------TSLNPY-MRVGEQLMEVLMLHKGlgkaeafeesvkmldavkmpearkrmrmfPHEFSG 171
Cdd:cd03369   79 DLR-SSLTIIPQDPTlfsgtirSNLDPFdEYSDEEIYGALRVSEG-----------------------------GLNLSQ 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 172 GMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNElkrEF-NTAIIMITHDLGVVAGiCDKVLVMYAGRTMEY 250
Cdd:cd03369  129 GQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTIRE---EFtNSTILTIAHRLRTIID-YDKILVMDAGEVKEY 204


                 .
gi 556427173 251 G 251
Cdd:cd03369  205 D 205

cbiO

PRK13634

cobalt transporter ATP-binding subunit; Provisional

38-268

2.64e-24

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 100.09 E-value: 2.64e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  38 AVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILN-LPEHELNKLRaEQISMIFQDPMts 116
Cdd:PRK13634  22 ALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTS---GTVTIGERVITAgKKNKKLKPLR-KKVGIVFQFPE-- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 117 lnpymrvgEQLMEVLMLHK--------GLGKAEAFEESVKMLDAVKMPEarKRMRMFPHEFSGGMRQRVMIAMALLCRPK 188
Cdd:PRK13634  96 --------HQLFEETVEKDicfgpmnfGVSEEDAKQKAREMIELVGLPE--ELLARSPFELSGGQMRRVAIAGVLAMEPE 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 189 LLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPYSIGL 268
Cdd:PRK13634 166 VLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPDELEAIGL 245

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

14-256

2.65e-24

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 103.34 E-value: 2.65e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   14 QQNNLLLDVKDLRVTFKTPD-GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANgviggSAKFN---GRE 89
Cdd:TIGR03269 274 EVGEPIIKVRNVSKRYISVDrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPT-----SGEVNvrvGDE 348

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   90 ILNLPEH-ELNKLRAEQ-ISMIFQDpmTSLNPYMRVGEQLMEVLMLHkgLGKAEAFEESVKMLDAVKMPE--ARKRMRMF 165
Cdd:TIGR03269 349 WVDMTKPgPDGRGRAKRyIGILHQE--YDLYPHRTVLDNLTEAIGLE--LPDELARMKAVITLKMVGFDEekAEEILDKY 424

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  166 PHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAG 245
Cdd:TIGR03269 425 PDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDG 504

                         250
                  ....*....|.
gi 556427173  246 RTMEYGKARDV 256
Cdd:TIGR03269 505 KIVKIGDPEEI 515

cbiO

PRK13645

energy-coupling factor transporter ATPase;

17-257

2.83e-24

energy-coupling factor transporter ATPase;

Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 100.08 E-value: 2.83e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  17 NLLLDVKDLRVTFKTPdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLL---AANGVIGGSAKFNGREILNl 93
Cdd:PRK13645   6 DIILDNVSYTYAKKTP-FEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIiseTGQTIVGDYAIPANLKKIK- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  94 pehELNKLRAEqISMIFQDPMTSLnpYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPeaRKRMRMFPHEFSGGM 173
Cdd:PRK13645  84 ---EVKRLRKE-IGLVFQFPEYQL--FQETIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLP--EDYVKRSPFELSGGQ 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 174 RQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKA 253
Cdd:PRK13645 156 KRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSP 235


                 ....
gi 556427173 254 RDVF 257
Cdd:PRK13645 236 FEIF 239

cbiO

PRK13631

cobalt transporter ATP-binding subunit; Provisional

16-261

3.16e-24

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 100.70 E-value: 3.16e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  16 NNLLLDVKDLRVTF--KTPDgDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANG--------VIGGSAKF 85
Cdd:PRK13631  18 DDIILRVKNLYCVFdeKQEN-ELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYgtiqvgdiYIGDKKNN 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  86 NGREILNLPEHELN--KLRaEQISMIFQDPmtslnPYMRVGEQLMEVLM---LHKGLGKAEAFEESVKMLdaVKMPEARK 160
Cdd:PRK13631  97 HELITNPYSKKIKNfkELR-RRVSMVFQFP-----EYQLFKDTIEKDIMfgpVALGVKKSEAKKLAKFYL--NKMGLDDS 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 161 RMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVL 240
Cdd:PRK13631 169 YLERSPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKAN-NKTVFVITHTMEHVLEVADEVI 247

                        250       260
                 ....*....|....*....|.
gi 556427173 241 VMYAGRTMEYGKARDVFYQPA 261
Cdd:PRK13631 248 VMDKGKILKTGTPYEIFTDQH 268

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

19-256

4.27e-24

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 102.41 E-value: 4.27e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTafaLM----GLLAANGvigGSAKFNGREI-LNL 93
Cdd:COG3845    5 ALELRGITKRF----GGVVANDDVSLTVRPGEIHALLGENGAGKS-T---LMkilyGLYQPDS---GEILIDGKPVrIRS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  94 PEHElnklRAEQISMIFQDPMtsLNPYMRVGEQLMevlmlhkgLGKaeafeESVKMLdAVKMPEARKRMRmfphEFSG-- 171
Cdd:COG3845   74 PRDA----IALGIGMVHQHFM--LVPNLTVAENIV--------LGL-----EPTKGG-RLDRKAARARIR----ELSEry 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 172 ---------------GMRQRVMIAMALLCRPKLLIADEPTTALdvTVQ--AQIMTLLNELKREfNTAIIMITHDLGVVAG 234
Cdd:COG3845  130 gldvdpdakvedlsvGEQQRVEILKALYRGARILILDEPTAVL--TPQeaDELFEILRRLAAE-GKSIIFITHKLREVMA 206

                        250       260
                 ....*....|....*....|..
gi 556427173 235 ICDKVLVMYAGRTMEYGKARDV 256
Cdd:COG3845  207 IADRVTVLRRGKVVGTVDTAET 228

potA

PRK09452

spermidine/putrescine ABC transporter ATP-binding protein PotA;

7-261

5.34e-24

spermidine/putrescine ABC transporter ATP-binding protein PotA;

Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 100.79 E-value: 5.34e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   7 ATAPQAQQQNNLLLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALM-GLLAANGvigGSAKF 85
Cdd:PRK09452   2 KKLNKQPSSLSPLVELRGISKSF----DGKEVISNLDLTINNGEFLTLLGPSGCGKT-TVLRLIaGFETPDS---GRIML 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  86 NGREILNLPehelnklrAEQ--ISMIFQDpmTSLNPYMRVGEQLMEVLMLHKgLGKAEaFEESVkmLDAVKMPEARKRMR 163
Cdd:PRK09452  74 DGQDITHVP--------AENrhVNTVFQS--YALFPHMTVFENVAFGLRMQK-TPAAE-ITPRV--MEALRMVQLEEFAQ 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 164 MFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMY 243
Cdd:PRK09452 140 RKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMR 219

                        250
                 ....*....|....*...
gi 556427173 244 AGRTMEYGKARDVFYQPA 261
Cdd:PRK09452 220 DGRIEQDGTPREIYEEPK 237

PRK10851

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

34-278

8.16e-24

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 100.16 E-value: 8.16e-24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLpeHElnklRAEQISMIFQDp 113
Cdd:PRK10851  13 GRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTS---GHIRFHGTDVSRL--HA----RDRKVGFVFQH- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 mTSLNPYMRVGEQL---MEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMIAMALLCRPKLL 190
Cdd:PRK10851  83 -YALFRHMTVFDNIafgLTVLPRRERPNAAAIKAKVTQLLEMVQLAHLADR---YPAQLSGGQKQRVALARALAVEPQIL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 191 IADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPYSIGLLN 270
Cdd:PRK10851 159 LLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFMG 238


                 ....*...
gi 556427173 271 AVPRLDAE 278
Cdd:PRK10851 239 EVNRLQGT 246

PRK10070

proline/glycine betaine ABC transporter ATP-binding protein ProV;

38-264

1.10e-23

proline/glycine betaine ABC transporter ATP-binding protein ProV;

Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 100.49 E-value: 1.10e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  38 AVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELNKLRAEQISMIFQDpmTSL 117
Cdd:PRK10070  43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTR---GQVLIDGVDIAKISDAELREVRRKKIAMVFQS--FAL 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 118 NPYMRVgeqlMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTT 197
Cdd:PRK10070 118 MPHMTV----LDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFS 193

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 198 ALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPY 264
Cdd:PRK10070 194 ALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDY 260

CydD

TIGR02857

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...

2-242

1.45e-23

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD

Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 101.21 E-value: 1.45e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173    2 TIIETATAPQAQQQNNLLLDVKDLR---VTFKTPDGDVtAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAangV 78
Cdd:TIGR02857 299 AVLDAAPRPLAGKAPVTAAPASSLEfsgVSVAYPGRRP-ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVD---P 374

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   79 IGGSAKFNGREILNLPEHELNKlraeQISMIFQdpmtslNPYMRVGeQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEA 158
Cdd:TIGR02857 375 TEGSIAVNGVPLADADADSWRD----QIAWVPQ------HPFLFAG-TIAENIRLARPDASDAEIREALERAGLDEFVAA 443

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  159 RKRMRMFP-----HEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVA 233
Cdd:TIGR02857 444 LPQGLDTPigeggAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLALAA 521


                  ....*....
gi 556427173  234 GiCDKVLVM 242
Cdd:TIGR02857 522 L-ADRIVVL 529

LivF

COG0410

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...

19-256

1.77e-23

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];

Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 96.59 E-value: 1.77e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAangVIGGSAKFNGREILNLPEHEL 98
Cdd:COG0410    3 MLEVENLHAGY----GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLP---PRSGSIRFDGEDITGLPPHRI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRaeqISM------IFqdpmtslnPYMRVGEQLMEVLMLHKGLGKAEAfeesvkMLDAVkmpearkrMRMFP--HEF- 169
Cdd:COG0410   76 ARLG---IGYvpegrrIF--------PSLTVEENLLLGAYARRDRAEVRA------DLERV--------YELFPrlKERr 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 170 -------SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVM 242
Cdd:COG0410  131 rqragtlSGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYVL 209

                        250
                 ....*....|....
gi 556427173 243 YAGRTMEYGKARDV 256
Cdd:COG0410  210 ERGRIVLEGTAAEL 223

btuD

PRK09536

corrinoid ABC transporter ATPase; Reviewed

20-256

1.84e-23

corrinoid ABC transporter ATPase; Reviewed

Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 99.92 E-value: 1.84e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTafalmgLLAANGVI---GGSAKFNGREILNLPEH 96
Cdd:PRK09536   4 IDVSDLSVEF----GDTTVLDGVDLSVREGSLVGLVGPNGAGKTTL------LRAINGTLtptAGTVLVAGDDVEALSAR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  97 ELNKlraeQISMIFQDpmTSLNPYMRVgEQLMEvLMLHKGLGKAEAFEESVKMldAVKMPEARKRMRMFPH----EFSGG 172
Cdd:PRK09536  74 AASR----RVASVPQD--TSLSFEFDV-RQVVE-MGRTPHRSRFDTWTETDRA--AVERAMERTGVAQFADrpvtSLSGG 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 173 MRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMItHDLGVVAGICDKVLVMYAGRTMEYGK 252
Cdd:PRK09536 144 ERQRVLLARALAQATPVLLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAI-HDLDLAARYCDELVLLADGRVRAAGP 222


                 ....
gi 556427173 253 ARDV 256
Cdd:PRK09536 223 PADV 226

ABCG_EPDR

cd03213

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...

20-251

4.42e-23

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.

Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 94.54 E-value: 4.42e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFKTPDGDVTA--VNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGViGGSAKFNGReilNLPEHE 97
Cdd:cd03213    4 LSFRNLTVTVKSSPSKSGKqlLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLGV-SGEVLINGR---PLDKRS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNKlraeQISMIFQDPMtsLNPYMRVGEQLMEVLMLhKGLgkaeafeesvkmldavkmpearkrmrmfphefSGGMRQRV 177
Cdd:cd03213   80 FRK----IIGYVPQDDI--LHPTLTVRETLMFAAKL-RGL--------------------------------SGGERKRV 120

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDL-GVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03213  121 SIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLADT-GRTIICSIHQPsSEIFELFDKLLLLSQGRVIYFG 194

SufC

COG0396

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...

20-246

5.45e-23

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 95.52 E-value: 5.45e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLlAANGVIGGSAKFNGREILNLPEHEln 99
Cdd:COG0396    1 LEIKNLHVSV----EGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGH-PKYEVTSGSILLDGEDILELSPDE-- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 klRA-EQISMIFQDPM------------TSLNpymRVGEQLMEVLMLHKGLGKAeafeesvkmLDAVKMPEArkrmrmFP 166
Cdd:COG0396   74 --RArAGIFLAFQYPVeipgvsvsnflrTALN---ARRGEELSAREFLKLLKEK---------MKELGLDED------FL 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 167 H-----EFSGGMRQRVMIA-MALLcRPKLLIADEPTTALDVTVqAQIMT-LLNELKREfNTAIIMITH-----DLGVVag 234
Cdd:COG0396  134 DryvneGFSGGEKKRNEILqMLLL-EPKLAILDETDSGLDIDA-LRIVAeGVNKLRSP-DRGILIITHyqrilDYIKP-- 208

                        250
                 ....*....|..
gi 556427173 235 icDKVLVMYAGR 246
Cdd:COG0396  209 --DFVHVLVDGR 218

xylG

TIGR02633

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

39-246

5.52e-23

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 99.13 E-value: 5.52e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   39 VNDLNFNLRAGETLGIVGESGSGKSQTAFALMGllAANGVIGGSAKFNGREI-LNLPEHELnklrAEQISMIFQD-PMTS 116
Cdd:TIGR02633 276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALFG--AYPGKFEGNVFINGKPVdIRNPAQAI----RAGIAMVPEDrKRHG 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  117 LNPYMRVGEQL-MEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFP-HEFSGGMRQRVMIAMALLCRPKLLIADE 194
Cdd:TIGR02633 350 IVPILGVGKNItLSVLKSFCFKMRIDAAAELQIIGSAIQRLKVKTASPFLPiGRLSGGNQQKAVLAKMLLTNPRVLILDE 429

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 556427173  195 PTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:TIGR02633 430 PTRGVDVGAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLSDRVLVIGEGK 480

PRK13549

xylose transporter ATP-binding subunit; Provisional

19-247

5.64e-23

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 99.23 E-value: 5.64e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAA---NGVIGGSAKFNGREIL--NL 93
Cdd:PRK13549   5 LLEMKNITKTF----GGVKALDNVSLKVRAGEIVSLCGENGAGKS----TLMKVLSGvypHGTYEGEIIFEGEELQasNI 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  94 PEHElnklrAEQISMIFQDPMtsLNPYMRVGEQ--LMEVLMLHKGLGKAEAFEESVKMLDAVKM---PEARKRmrmfphE 168
Cdd:PRK13549  77 RDTE-----RAGIAIIHQELA--LVKELSVLENifLGNEITPGGIMDYDAMYLRAQKLLAQLKLdinPATPVG------N 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 169 FSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRT 247
Cdd:PRK13549 144 LGLGQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGRH 221

ABC_FeS_Assembly

cd03217

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...

20-251

8.21e-23

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.

Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 94.13 E-value: 8.21e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTfktpDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANgVIGGSAKFNGREILNLPEHEln 99
Cdd:cd03217    1 LEIKDLHVS----VGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKYE-VTEGEILFKGEDITDLPPEE-- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 klRAEQ-ISMIFQDPMtslnpymrvgeqlmEVlmlhkglgkaeafeESVKMLDAVkmpearkrmRMFPHEFSGGMRQRVM 178
Cdd:cd03217   74 --RARLgIFLAFQYPP--------------EI--------------PGVKNADFL---------RYVNEGFSGGEKKRNE 114

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGI-CDKVLVMYAGRTMEYG 251
Cdd:cd03217  115 ILQLLLLEPDLAILDEPDSGLDIDALRLVAEVINKLREE-GKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSG 187

PRK14246

phosphate ABC transporter ATP-binding protein; Provisional

35-260

9.04e-23

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 95.50 E-value: 9.04e-23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  35 DVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLA---ANGVIGGSAKFNGREILNLPEHELNKlraeQISMIFQ 111
Cdd:PRK14246  22 DKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiydSKIKVDGKVLYFGKDIFQIDAIKLRK----EVGMVFQ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 112 DPmtSLNPYMRVGEQLMEVLMLHKGLGKAEA---FEESVKMLDAVKmpEARKRMRMFPHEFSGGMRQRVMIAMALLCRPK 188
Cdd:PRK14246  98 QP--NPFPHLSIYDNIAYPLKSHGIKEKREIkkiVEECLRKVGLWK--EVYDRLNSPASQLSGGQQQRLTIARALALKPK 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556427173 189 LLIADEPTTALDVTVQAQIMTLLNELKREFntAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQP 260
Cdd:PRK14246 174 VLLMDEPTSMIDIVNSQAIEKLITELKNEI--AIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSP 243

ArpD

COG4618

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...

26-257

1.21e-22

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];

Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 98.67 E-value: 1.21e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  26 RVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREILNLPEHELnklrAEQ 105
Cdd:COG4618  335 NLTVVPPGSKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPP---TAGSVRLDGADLSQWDREEL----GRH 407

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 106 ISMIFQDPmtslnpymrvgeqlmevlmlhkglgkaEAFEESVK-------MLDAVKMPEARKRMRMfpHEF--------- 169
Cdd:COG4618  408 IGYLPQDV---------------------------ELFDGTIAeniarfgDADPEKVVAAAKLAGV--HEMilrlpdgyd 458

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 170 ----------SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAgICDKV 239
Cdd:COG4618  459 trigeggarlSGGQRQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKAR-GATVVVITHRPSLLA-AVDKL 536

                        250
                 ....*....|....*...
gi 556427173 240 LVMYAGRTMEYGKARDVF 257
Cdd:COG4618  537 LVLRDGRVQAFGPRDEVL 554

ABCC_Protease_Secretion

cd03246

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...

26-246

1.27e-22

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.

Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 92.66 E-value: 1.27e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  26 RVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAangVIGGSAKFNGREILNLPEHELNKlraeQ 105
Cdd:cd03246    5 NVSFRYPGAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLR---PTSGRVRLDGADISQWDPNELGD----H 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 106 ISMIFQDpmtslnpymrvgeqlmevlmlhkglgkAEAFEESVkmLDAVkmpearkrmrmfpheFSGGMRQRVMIAMALLC 185
Cdd:cd03246   78 VGYLPQD---------------------------DELFSGSI--AENI---------------LSGGQRQRLGLARALYG 113

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556427173 186 RPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAgICDKVLVMYAGR 246
Cdd:cd03246  114 NPRILVLDEPNSHLDVEGERALNQAIAALKAAGAT-RIVIAHRPETLA-SADRILVLEDGR 172

cbiO

PRK13646

energy-coupling factor transporter ATPase;

38-259

1.35e-22

energy-coupling factor transporter ATPase;

Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 95.62 E-value: 1.35e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  38 AVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILN-LPEHELNKLRaEQISMIFQDPMTS 116
Cdd:PRK13646  22 AIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTT---GTVTVDDITITHkTKDKYIRPVR-KRIGMVFQFPESQ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 117 LnpYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPeaRKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPT 196
Cdd:PRK13646  98 L--FEDTVEREIIFGPKNFKMNLDEVKNYAHRLLMDLGFS--RDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPT 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173 197 TALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQ 259
Cdd:PRK13646 174 AGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKD 236

fbpC

PRK11432

ferric ABC transporter ATP-binding protein;

15-261

2.26e-22

ferric ABC transporter ATP-binding protein;

Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 95.94 E-value: 2.26e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  15 QNNLLLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNlp 94
Cdd:PRK11432   2 TQKNFVVLKNITKRF----GSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTE---GQIFIDGEDVTH-- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  95 ehelNKLRAEQISMIFQDpmTSLNPYMRVGEQLMEVL-MLhkGLGKAEAFE---ESVKMLDAVKMpEARkrmrmFPHEFS 170
Cdd:PRK11432  73 ----RSIQQRDICMVFQS--YALFPHMSLGENVGYGLkML--GVPKEERKQrvkEALELVDLAGF-EDR-----YVDQIS 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEY 250
Cdd:PRK11432 139 GGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQI 218

                        250
                 ....*....|.
gi 556427173 251 GKARDVFYQPA 261
Cdd:PRK11432 219 GSPQELYRQPA 229

PRK11174

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

1-251

2.42e-22

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 97.61 E-value: 2.42e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   1 MTIIETATAPQAQQQNNLLLD------VKDLRVTfkTPDGDVTAVNdLNFNLRAGETLGIVGESGSGKSQTAFALMGLLA 74
Cdd:PRK11174 325 VTFLETPLAHPQQGEKELASNdpvtieAEDLEIL--SPDGKTLAGP-LNFTLPAGQRIALVGPSGAGKTSLLNALLGFLP 401

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  75 ANGviggSAKFNGREILNLpehELNKLRaEQISMIFQDPmtslnpymrvgeQLME------VLmlhkgLGKAEAFEESVK 148
Cdd:PRK11174 402 YQG----SLKINGIELREL---DPESWR-KHLSWVGQNP------------QLPHgtlrdnVL-----LGNPDASDEQLQ 456

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 149 MLDAvkmpearkrmRMFPHEF-------------------SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMT 209
Cdd:PRK11174 457 QALE----------NAWVSEFlpllpqgldtpigdqaaglSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSEQLVMQ 526

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 556427173 210 LLNELKREFNTaiIMITHDLGVVAGiCDKVLVMYAGRTMEYG 251
Cdd:PRK11174 527 ALNAASRRQTT--LMVTHQLEDLAQ-WDQIWVMQDGQIVQQG 565

PRK13657

glucan ABC transporter ATP-binding protein/ permease;

10-251

2.69e-22

glucan ABC transporter ATP-binding protein/ permease;

Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 97.72 E-value: 2.69e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  10 PQAQQQNNLLLDVKDLRVTFKTpDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALmgLLAANGVIGGSAKFNGRE 89
Cdd:PRK13657 323 PGAIDLGRVKGAVEFDDVSFSY-DNSRQGVEDVSFEAKPGQTVAIVGPTGAGKS-TLINL--LQRVFDPQSGRILIDGTD 398

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  90 ILNLpehELNKLRaEQISMIFQDPM---TSLNPYMRVGEQLMEVLMLHKGLGKAEA---FEESVKMLDAVkmpeARKRMR 163
Cdd:PRK13657 399 IRTV---TRASLR-RNIAVVFQDAGlfnRSIEDNIRVGRPDATDEEMRAAAERAQAhdfIERKPDGYDTV----VGERGR 470

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 164 MFphefSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIimITHDLGVVAGiCDKVLVMY 243
Cdd:PRK13657 471 QL----SGGERQRLAIARALLKDPPILILDEATSALDVETEAKVKAALDELMKGRTTFI--IAHRLSTVRN-ADRILVFD 543


                 ....*...
gi 556427173 244 AGRTMEYG 251
Cdd:PRK13657 544 NGRVVESG 551

PRK13549

xylose transporter ATP-binding subunit; Provisional

39-246

2.94e-22

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 97.31 E-value: 2.94e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  39 VNDLNFNLRAGETLGIVGESGSGKSQTAFALMGllAANGVIGGSAKFNGREI-LNLPEHELnklrAEQISMIFQD-PMTS 116
Cdd:PRK13549 278 VDDVSFSLRRGEILGIAGLVGAGRTELVQCLFG--AYPGRWEGEIFIDGKPVkIRNPQQAI----AQGIAMVPEDrKRDG 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 117 LNPYMRVGE--------QLMEVLMLHKGLgKAEAFEESVKMLdAVKMPEARKRMRmfphEFSGGMRQRVMIAMALLCRPK 188
Cdd:PRK13549 352 IVPVMGVGKnitlaaldRFTGGSRIDDAA-ELKTILESIQRL-KVKTASPELAIA----RLSGGNQQKAVLAKCLLLNPK 425

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 189 LLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PRK13549 426 ILILDEPTRGIDVGAKYEIYKLINQLVQQ-GVAIIVISSELPEVLGLSDRVLVMHEGK 482

ABCC_bacteriocin_exporters

cd03245

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...

27-246

3.41e-22

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.

Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 93.04 E-value: 3.41e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELNKlraeQI 106
Cdd:cd03245    8 VSFSYPNQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTS---GSVLLDGTDIRQLDPADLRR----NI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 107 SMIFQDPMTSlnpYMRVGEQLMevlmlhkgLGKAEAfeESVKMLDAVKMPEARKRMRMFPHEF-----------SGGMRQ 175
Cdd:cd03245   81 GYVPQDVTLF---YGTLRDNIT--------LGAPLA--DDERILRAAELAGVTDFVNKHPNGLdlqigergrglSGGQRQ 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556427173 176 RVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfnTAIIMITHDLGVVAgICDKVLVMYAGR 246
Cdd:cd03245  148 AVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGD--KTLIIITHRPSLLD-LVDRIIVMDSGR 215

ABCC_MsbA

cd03251

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...

20-251

3.52e-22

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 93.06 E-value: 3.52e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDlrVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAA-NGVIGGSAKFNGREIlnlPEHEL 98
Cdd:cd03251    1 VEFKN--VTFRYPGDGPPVLRDISLDIPAGETVALVGPSGSGKS----TLVNLIPRfYDVDSGRILIDGHDV---RDYTL 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLRaEQISMIFQDPM----TslnpymrVGEQLMevlmlhkgLGKAEAFEESVkmLDAVKMPEARKRMRMFPHEF----- 169
Cdd:cd03251   72 ASLR-RQIGLVSQDVFlfndT-------VAENIA--------YGRPGATREEV--EEAARAANAHEFIMELPEGYdtvig 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 170 ------SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIImITHDLGVVAGIcDKVLVMY 243
Cdd:cd03251  134 ergvklSGGQRQRIAIARALLKDPPILILDEATSALDTESERLVQAALERLMKN-RTTFV-IAHRLSTIENA-DRIVVLE 210


                 ....*...
gi 556427173 244 AGRTMEYG 251
Cdd:cd03251  211 DGKIVERG 218

cbiO

PRK13641

energy-coupling factor transporter ATPase;

39-257

4.76e-22

energy-coupling factor transporter ATPase;

Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 94.13 E-value: 4.76e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  39 VNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREI-LNLPEHELNKLRaEQISMIFQDPMTSL 117
Cdd:PRK13641  23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSS---GTITIAGYHItPETGNKNLKKLR-KKVSLVFQFPEAQL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 118 npymrVGEQLMEVLM---LHKGLGKAEAFEESVKMLDAVKMPEarKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADE 194
Cdd:PRK13641  99 -----FENTVLKDVEfgpKNFGFSEDEAKEKALKWLKKVGLSE--DLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDE 171

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173 195 PTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVF 257
Cdd:PRK13641 172 PAAGLDPEGRKEMMQLFKDYQKAGHT-VILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIF 233

ABCC_Hemolysin

cd03252

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...

26-252

8.04e-22

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.

Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 92.16 E-value: 8.04e-22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  26 RVTFK-TPDGDVtAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANgviggsakfNGREILN---LPEHELNKL 101
Cdd:cd03252    5 HVRFRyKPDGPV-ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPE---------NGRVLVDghdLALADPAWL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 102 RAeQISMIFQDPmTSLNPYMRVGEQLMEVLMlhkglgKAEAFEESVKMLDA----VKMPEARKRMRmfpHE----FSGGM 173
Cdd:cd03252   75 RR-QVGVVLQEN-VLFNRSIRDNIALADPGM------SMERVIEAAKLAGAhdfiSELPEGYDTIV---GEqgagLSGGQ 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 174 RQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAGiCDKVLVMYAGRTMEYGK 252
Cdd:cd03252  144 RQRIAIARALIHNPRILIFDEATSALDYESEHAIMRNMHDICA--GRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGS 219

ABCC_cytochrome_bd

cd03247

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...

27-251

1.54e-21

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.

Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 90.06 E-value: 1.54e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlnlpeHELNKLRAEQI 106
Cdd:cd03247    6 VSFSYPEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQ---GEITLDGVPV-----SDLEKALSSLI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 107 SMIFQDPM---TSLnpYMRVGEQlmevlmlhkglgkaeafeesvkmldavkmpearkrmrmfpheFSGGMRQRVMIAMAL 183
Cdd:cd03247   78 SVLNQRPYlfdTTL--RNNLGRR------------------------------------------FSGGERQRLALARIL 113

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 184 LCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAGIcDKVLVMYAGRTMEYG 251
Cdd:cd03247  114 LQDAPIVLLDEPTVGLDPITERQLLSLIFEVLK--DKTLIWITHHLTGIEHM-DKILFLENGKIIMQG 178

livG

PRK11300

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

19-256

1.60e-21

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 91.98 E-value: 1.60e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHEL 98
Cdd:PRK11300   5 LLSVSGLMMRF----GGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTG---GTILLRGQHIEGLPGHQI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKL---RAEQISMIFQDpMTSLNPYMRVGEQLMEVLMLHkGLGK--------AEAFEESVKMLDAVKMPEARKRMrmfPH 167
Cdd:PRK11300  78 ARMgvvRTFQHVRLFRE-MTVIENLLVAQHQQLKTGLFS-GLLKtpafrraeSEALDRAATWLERVGLLEHANRQ---AG 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 168 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRT 247
Cdd:PRK11300 153 NLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTP 232


                 ....*....
gi 556427173 248 MEYGKARDV 256
Cdd:PRK11300 233 LANGTPEEI 241

ABC_YhbG

cd03218

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...

37-257

1.91e-21

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.

Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 91.07 E-value: 1.91e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  37 TAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHElnklRAE-------QISMI 109
Cdd:cd03218   14 KVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDS---GKILLDGQDITKLPMHK----RARlgigylpQEASI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 110 FQDpmtslnpyMRVGEQLMEVLMLHKgLGKAEAFEESVKMLDAVKMPEARKRMRMFpheFSGGMRQRVMIAMALLCRPKL 189
Cdd:cd03218   87 FRK--------LTVEENILAVLEIRG-LSKKEREEKLEELLEEFHITHLRKSKASS---LSGGERRRVEIARALATNPKF 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 190 LIADEPTTALDVTVQAQIMTLLNELKrefNTAI-IMIT-HDLGVVAGICDKVLVMYAGRTMEYGKARDVF 257
Cdd:cd03218  155 LLLDEPFAGVDPIAVQDIQKIIKILK---DRGIgVLITdHNVRETLSITDRAYIIYEGKVLAEGTPEEIA 221

ssuB

PRK11247

aliphatic sulfonates transport ATP-binding subunit; Provisional

20-294

4.20e-21

aliphatic sulfonates transport ATP-binding subunit; Provisional

Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 90.89 E-value: 4.20e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANG--VIGGSAKfngreilnlpehe 97
Cdd:PRK11247  13 LLLNAVSKRY----GERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAgeLLAGTAP------------- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 LNKLRaEQISMIFQDpmTSLNPYMRVGEQLmevlmlhkGLG-KAEAFEESVKMLDAVKMPEarkRMRMFPHEFSGGMRQR 176
Cdd:PRK11247  76 LAEAR-EDTRLMFQD--ARLLPWKKVIDNV--------GLGlKGQWRDAALQALAAVGLAD---RANEWPAALSGGQKQR 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 177 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTmeygkARDV 256
Cdd:PRK11247 142 VALARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI-----GLDL 216

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 556427173 257 FYQPAHPYSIGllnaVPRLDA-EGESL---LTIPGNPPNLLR 294
Cdd:PRK11247 217 TVDLPRPRRRG----SARLAElEAEVLqrvMSRGESEPTRLR 254

thiQ

TIGR01277

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...

43-252

4.81e-21

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]

Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 89.54 E-value: 4.81e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   43 NFNLRAGETLGIVGESGSGKSqtafALMGLLAanGVI---GGSAKFNGREILNLPEHElnklraEQISMIFQDpmTSLNP 119
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKS----TLLNLIA--GFIepaSGSIKVNDQSHTGLAPYQ------RPVSMLFQE--NNLFA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  120 YMRVGEQLmeVLMLHKGLgKAEAfEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTAL 199
Cdd:TIGR01277  84 HLTVRQNI--GLGLHPGL-KLNA-EQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSAL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 556427173  200 DVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGK 252
Cdd:TIGR01277 160 DPLLREEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVSD 212

PRK10908

cell division ATP-binding protein FtsE;

34-246

7.72e-21

cell division ATP-binding protein FtsE;

Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 89.16 E-value: 7.72e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELNKLRaEQISMIFQDP 113
Cdd:PRK10908  13 GGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSA---GKIWFSGHDITRLKNREVPFLR-RQIGMIFQDH 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 MTSLNpymRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEarkRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIAD 193
Cdd:PRK10908  89 HLLMD---RTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLD---KAKNFPIQLSGGEQQRVGIARAVVNKPAVLLAD 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 556427173 194 EPTTALDVTVQAQIMTLLNELKReFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PRK10908 163 EPTGNLDDALSEGILRLFEEFNR-VGVTVLMATHDIGLISRRSYRMLTLSDGH 214

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

41-246

7.92e-21

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 92.81 E-value: 7.92e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  41 DLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILN-------------LPEHElnklraeQIS 107
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARG---GRIMLNGKEINAlstaqrlarglvyLPEDR-------QSS 350

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 108 MIFQDPMTSLNPYMRVGEQLMevLMLHKGLGKAeAFEESVKMLDaVKMPEARKRMRmfphEFSGGMRQRVMIAMALLCRP 187
Cdd:PRK15439 351 GLYLDAPLAWNVCALTHNRRG--FWIKPARENA-VLERYRRALN-IKFNHAEQAAR----TLSGGNQQKVLIAKCLEASP 422

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 188 KLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PRK15439 423 QLLIVDEPTRGVDVSARNDIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLVMHQGE 480

YddA

COG4178

ABC-type uncharacterized transport system, permease and ATPase components [General function ...

20-227

9.42e-21

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];

Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 92.95 E-value: 9.42e-21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTfkTPDGDVTaVNDLNFNLRAGETLGIVGESGSGKSqTAF-ALMGL-LAANGVIGGSAkfnGREILNLPEHe 97
Cdd:COG4178  363 LALEDLTLR--TPDGRPL-LEDLSLSLKPGERLLITGPSGSGKS-TLLrAIAGLwPYGSGRIARPA---GARVLFLPQR- 434

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 lnklraeqismifqdpmtslnPYMRVGEqLMEVLmlhkgL--GKAEAF--EESVKMLDAVKMPEARKRM---RMFPHEFS 170
Cdd:COG4178  435 ---------------------PYLPLGT-LREAL-----LypATAEAFsdAELREALEAVGLGHLAERLdeeADWDQVLS 487

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNElkREFNTAIIMITH 227
Cdd:COG4178  488 LGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLLRE--ELPGTTVISVGH 542

znuC

PRK09544

high-affinity zinc transporter ATPase; Reviewed

19-240

1.20e-20

high-affinity zinc transporter ATPase; Reviewed

Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 89.40 E-value: 1.20e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLA-ANGVIGGSAKFngrEILNLPEHe 97
Cdd:PRK09544   4 LVSLENVSVSF----GQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVApDEGVIKRNGKL---RIGYVPQK- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  98 lnklraeqismIFQDPMTSLNpymrvgeqLMEVLMLHKGLGKAEafeesvkMLDAVKMPEARKRMRMFPHEFSGGMRQRV 177
Cdd:PRK09544  76 -----------LYLDTTLPLT--------VNRFLRLRPGTKKED-------ILPALKRVQAGHLIDAPMQKLSGGETQRV 129

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVL 240
Cdd:PRK09544 130 LLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEVL 192

xylG

TIGR02633

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

19-267

1.24e-20

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 92.58 E-value: 1.24e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAA---NGVIGGSAKFNGREilnLPE 95
Cdd:TIGR02633   1 LLEMKGIVKTF----GGVKALDGIDLEVRPGECVGLCGENGAGKS----TLMKILSGvypHGTWDGEIYWSGSP---LKA 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   96 HELNKLRAEQISMIFQDPMtsLNPYMRVGEQL-MEVLMLHKG--LGKAEAFEESVKMLDAVK---MPEARKRMrmfphEF 169
Cdd:TIGR02633  70 SNIRDTERAGIVIIHQELT--LVPELSVAENIfLGNEITLPGgrMAYNAMYLRAKNLLRELQldaDNVTRPVG-----DY 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  170 SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR--- 246
Cdd:TIGR02633 143 GGGQQQLVEIAKALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQhva 221

                         250       260       270
                  ....*....|....*....|....*....|....
gi 556427173  247 -------------TMEYGKARDVFYqPAHPYSIG 267
Cdd:TIGR02633 222 tkdmstmseddiiTMMVGREITSLY-PHEPHEIG 254

BtuD

COG4138

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...

42-283

1.37e-20

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];

Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 89.13 E-value: 1.37e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  42 LNFNLRAGETLGIVGESGSGKSqTAFALM-GLLAANGVIggsaKFNGREILNLPEHELNKLRAeqisMIFQDPMTSLNpy 120
Cdd:COG4138   15 ISAQVNAGELIHLIGPNGAGKS-TLLARMaGLLPGQGEI----LLNGRPLSDWSAAELARHRA----YLSQQQSPPFA-- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 121 MRVGEQLMevLMLHKGLGKAEAFEESVKMLDAVKMpeARKRMRMFpHEFSGGMRQRVMIAMALL-------CRPKLLIAD 193
Cdd:COG4138   84 MPVFQYLA--LHQPAGASSEAVEQLLAQLAEALGL--EDKLSRPL-TQLSGGEWQRVRLAAVLLqvwptinPEGQLLLLD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 194 EPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFyQP---AHPYSIglln 270
Cdd:COG4138  159 EPMNSLDVAQQAALDRLLRELCQQGIT-VVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVM-TPenlSEVFGV---- 232

                        250
                 ....*....|...
gi 556427173 271 AVPRLDAEGESLL 283
Cdd:COG4138  233 KFRRLEVEGHRWL 245

TagH

COG1134

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...

30-256

1.75e-20

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 88.60 E-value: 1.75e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  30 KTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTafaLMGLLAanGVI---GGSAKFNGReilnlpehelnklraeqI 106
Cdd:COG1134   33 RTRREEFWALKDVSFEVERGESVGIIGRNGAGKS-T---LLKLIA--GILeptSGRVEVNGR-----------------V 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 107 SMIFqDPMTSLNPYMRVGEQLMEVLMLHkGLGKAE---------AFEEsvkmL-DAVKMPearkrMRMFphefSGGMRQR 176
Cdd:COG1134   90 SALL-ELGAGFHPELTGRENIYLNGRLL-GLSRKEidekfdeivEFAE----LgDFIDQP-----VKTY----SSGMRAR 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 177 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:COG1134  155 LAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRES-GRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEV 233

ABCC_Glucan_exporter_like

cd03254

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...

33-251

2.45e-20

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 88.05 E-value: 2.45e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  33 DGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANgviGGSAKFNGREILNLPEHELNklraEQISMIFQD 112
Cdd:cd03254   13 DEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQ---KGQILIDGIDIRDISRKSLR----SMIGVVLQD 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 113 PM---TSLNPYMRVGEQLM---EVLMLHKGLGKAEAFEESVKMLDAVKMPEArkrmrmfpHEFSGGMRQRVMIAMALLCR 186
Cdd:cd03254   86 TFlfsGTIMENIRLGRPNAtdeEVIEAAKEAGAHDFIMKLPNGYDTVLGENG--------GNLSQGERQLLAIARAMLRD 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 187 PKLLIADEPTTALDV----TVQAQIMTLLNelkrefNTAIIMITHDLGVVAGiCDKVLVMYAGRTMEYG 251
Cdd:cd03254  158 PKILILDEATSNIDTetekLIQEALEKLMK------GRTSIIIAHRLSTIKN-ADKILVLDDGKIIEEG 219

ycf16

CHL00131

sulfate ABC transporter protein; Validated

16-253

2.47e-20

sulfate ABC transporter protein; Validated

Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 88.55 E-value: 2.47e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  16 NNLLLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANgVIGGSAKFNGREILNLPE 95
Cdd:CHL00131   4 NKPILEIKNLHASV----NENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPAYK-ILEGDILFKGESILDLEP 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  96 HElnklRAEQ-ISMIFQDPMTSlnpymrVGEQLMEVLML-----HKGLGKAEA-----FEESVKMLDAVKMpEARKRMRM 164
Cdd:CHL00131  79 EE----RAHLgIFLAFQYPIEI------PGVSNADFLRLaynskRKFQGLPELdplefLEIINEKLKLVGM-DPSFLSRN 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 165 FPHEFSGGMRQRVMI-AMALLcRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGIC-DKVLVM 242
Cdd:CHL00131 148 VNEGFSGGEKKRNEIlQMALL-DSELAILDETDSGLDIDALKIIAEGINKLMTS-ENSIILITHYQRLLDYIKpDYVHVM 225

                        250
                 ....*....|.
gi 556427173 243 YAGRTMEYGKA 253
Cdd:CHL00131 226 QNGKIIKTGDA 236

ntrCD

TIGR01184

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...

39-262

2.59e-20

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]

Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 87.91 E-value: 2.59e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   39 VNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAAngviggsakfngreiLNLPEHELNKLRAEQIS-------MIFQ 111
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKS----TLLNLISG---------------LAQPTSGGVILEGKQITepgpdrmVVFQ 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  112 DpmTSLNPYMRVGEQL-MEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMIAMALLCRPKLL 190
Cdd:TIGR01184  62 N--YSLLPWLTVRENIaLAVDRVLPDLSKSERRAIVEEHIALVGLTEAADK---RPGQLSGGMKQRVAIARALSIRPKVL 136

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173  191 IADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV-FYQPAH 262
Cdd:TIGR01184 137 LLDEPFGALDALTRGNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQILEVpFPRPRD 209

tauB

PRK11248

taurine ABC transporter ATP-binding subunit;

38-229

2.60e-20

taurine ABC transporter ATP-binding subunit;

Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 88.60 E-value: 2.60e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  38 AVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAanGVI---GGSAKFNGREIlnlpehelNKLRAEQiSMIFQDpm 114
Cdd:PRK11248  16 ALEDINLTLESGELLVVLGPSGCGKT----TLLNLIA--GFVpyqHGSITLDGKPV--------EGPGAER-GVVFQN-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 115 TSLNPYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEARKRmrmFPHEFSGGMRQRVMIAMALLCRPKLLIADE 194
Cdd:PRK11248  79 EGLLPWRNVQDNVAFGLQL-AGVEKMQRLEIAHQMLKKVGLEGAEKR---YIWQLSGGQRQRVGIARALAANPQLLLLDE 154

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 556427173 195 PTTALDVTVQAQIMTLLNELKREFNTAIIMITHDL 229
Cdd:PRK11248 155 PFGALDAFTREQMQTLLLKLWQETGKQVLLITHDI 189

cbiO

PRK13652

cobalt transporter ATP-binding subunit; Provisional

19-260

2.68e-20

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 89.09 E-value: 2.68e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKtpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHEL 98
Cdd:PRK13652   3 LIETRDLCYSYS---GSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTS---GSVLIRGEPITKENIREV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NKLraeqISMIFQDPMTSLnpYMRVGEQLMEVLMLHKGLGK---AEAFEESVKMLDavkMPEARKRMrmfPHEFSGGMRQ 175
Cdd:PRK13652  77 RKF----VGLVFQNPDDQI--FSPTVEQDIAFGPINLGLDEetvAHRVSSALHMLG---LEELRDRV---PHHLSGGEKK 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 176 RVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARD 255
Cdd:PRK13652 145 RVAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEE 224


                 ....*
gi 556427173 256 VFYQP 260
Cdd:PRK13652 225 IFLQP 229

PRK10762

D-ribose transporter ATP binding protein; Provisional

39-246

2.83e-20

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 91.22 E-value: 2.83e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  39 VNDLNFNLRAGETLGIVGESGSGKSQtafaLMGLL-AANGVIGGSAKFNGREILNL-PEHELnklrAEQISMIFQD---- 112
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTE----LMKVLyGALPRTSGYVTLDGHEVVTRsPQDGL----ANGIVYISEDrkrd 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 113 ------------PMTSLNPYMRVGEQLmevlmlhKGLGKAEAFEESVKMLDaVKMPEARKRMRMFphefSGGMRQRVMIA 180
Cdd:PRK10762 340 glvlgmsvkenmSLTALRYFSRAGGSL-------KHADEQQAVSDFIRLFN-IKTPSMEQAIGLL----SGGNQQKVAIA 407

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556427173 181 MALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PRK10762 408 RGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAE-GLSIILVSSEMPEVLGMSDRILVMHEGR 472

cbiO

PRK13638

energy-coupling factor ABC transporter ATP-binding protein;

29-257

7.56e-20

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 87.76 E-value: 7.56e-20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  29 FKTPDGDVTAVNDLNFNLRAgeTLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGrEILNLPEHELNKLRaEQISM 108
Cdd:PRK13638   9 FRYQDEPVLKGLNLDFSLSP--VTGLVGANGCGKSTLFMNLSGLLRPQK---GAVLWQG-KPLDYSKRGLLALR-QQVAT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 109 IFQDPMTSLNpYMRVGEQLMEVLmlhKGLGKAEAfEESVKMLDAVKMPEArKRMRMFPHE-FSGGMRQRVMIAMALLCRP 187
Cdd:PRK13638  82 VFQDPEQQIF-YTDIDSDIAFSL---RNLGVPEA-EITRRVDEALTLVDA-QHFRHQPIQcLSHGQKKRVAIAGALVLQA 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 188 KLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMiTHDLGVVAGICDKVLVMYAGRTMEYGKARDVF 257
Cdd:PRK13638 156 RYLLLDEPTAGLDPAGRTQMIAIIRRIVAQGNHVIIS-SHDIDLIYEISDAVYVLRQGQILTHGAPGEVF 224

CydC

TIGR02868

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...

20-229

1.32e-19

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.

Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 89.34 E-value: 1.32e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   20 LDVKDLRVTFktpDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREILNLPEHELN 99
Cdd:TIGR02868 335 LELRDLSAGY---PGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDP---LQGEVTLDGVPVSSLDQDEVR 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  100 KLraeqISMIFQDPM---TSLNPYMRVG------EQLMEVLmlhKGLGKAEAFEESVKMLDAVKMPEARKrmrmfpheFS 170
Cdd:TIGR02868 409 RR----VSVCAQDAHlfdTTVRENLRLArpdatdEELWAAL---ERVGLADWLRALPDGLDTVLGEGGAR--------LS 473

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173  171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfnTAIIMITHDL 229
Cdd:TIGR02868 474 GGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLAALSG--RTVVLITHHL 530

ABC_KpsT_Wzt

cd03220

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...

23-251

1.32e-19

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.

Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 86.05 E-value: 1.32e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  23 KDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAanGVI---GGSAKFNGReilnlpeheln 99
Cdd:cd03220   22 KLGILGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKS----TLLRLLA--GIYppdSGTVTVRGR----------- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 klraeqISMIFqDPMTSLNPYMRVGEQLMEVLMLHkGLGKAE--AFEESVKML----DAVKMPearkrMRmfphEFSGGM 173
Cdd:cd03220   85 ------VSSLL-GLGGGFNPELTGRENIYLNGRLL-GLSRKEidEKIDEIIEFselgDFIDLP-----VK----TYSSGM 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 174 RQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:cd03220  148 KARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQ-GKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224

MsbA_lipidA

TIGR02203

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...

27-255

1.56e-19

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]

Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 89.39 E-value: 1.56e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   27 VTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlnlPEHELNKLRAeQI 106
Cdd:TIGR02203 336 VTFRYPGRDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDS---GQILLDGHDL---ADYTLASLRR-QV 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  107 SMIFQDPM----TSLN--PYMRVGEQLMEvlMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMfphefSGGMRQRVMIA 180
Cdd:TIGR02203 409 ALVSQDVVlfndTIANniAYGRTEQADRA--EIERALAAAYAQDFVDKLPLGLDTPIGENGVLL-----SGGQRQRLAIA 481

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173  181 MALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaiIMITHDLGVVAGiCDKVLVMYAGRTMEYGKARD 255
Cdd:TIGR02203 482 RALLKDAPILILDEATSALDNESERLVQAALERLMQGRTT--LVIAHRLSTIEK-ADRIVVMDDGRIVERGTHNE 553

PRK14271

phosphate ABC transporter ATP-binding protein; Provisional

37-262

1.70e-19

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 86.69 E-value: 1.70e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  37 TAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGL--------LAANGVIGGSAKFNGREILNLpehelnklrAEQISM 108
Cdd:PRK14271  35 TVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMndkvsgyrYSGDVLLGGRSIFNYRDVLEF---------RRRVGM 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 109 IFQDPmtslNPY-MRVGEQLMEVLMLHKGL------GKAEAFEESVKMLDAVKmpearKRMRMFPHEFSGGMRQRVMIAM 181
Cdd:PRK14271 106 LFQRP----NPFpMSIMDNVLAGVRAHKLVprkefrGVAQARLTEVGLWDAVK-----DRLSDSPFRLSGGQQQLLCLAR 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 182 ALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFntAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPA 261
Cdd:PRK14271 177 TLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADRL--TVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPK 254


                 .
gi 556427173 262 H 262
Cdd:PRK14271 255 H 255

type_I_sec_PrtD

TIGR01842

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...

26-256

1.83e-19

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 88.94 E-value: 1.83e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   26 RVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREILNLPEHELNKlraeQ 105
Cdd:TIGR01842 321 NVTIVPPGGKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPP---TSGSVRLDGADLKQWDRETFGK----H 393

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  106 ISMIFQD----PMTSLNPYMRVGEQLmevlmlhkglgkaeafeESVKMLDAVKMPEARKRMRMFPHEF-----------S 170
Cdd:TIGR01842 394 IGYLPQDvelfPGTVAENIARFGENA-----------------DPEKIIEAAKLAGVHELILRLPDGYdtvigpggatlS 456

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIImITHDLGVVAGIcDKVLVMYAGRTMEY 250
Cdd:TIGR01842 457 GGQRQRIALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKALKARGITVVV-ITHRPSLLGCV-DKILVLQDGRIARF 534


                  ....*.
gi 556427173  251 GKARDV 256
Cdd:TIGR01842 535 GERDEV 540

ABCG_White

cd03234

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...

29-227

1.99e-19

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.

Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 85.40 E-value: 1.99e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  29 FKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKFNGREilnlpehelnkLRAEQ--- 105
Cdd:cd03234   13 AKNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGTTSGQILFNGQP-----------RKPDQfqk 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 106 -ISMIFQDpmTSLNPYMRVGEQL--MEVLMLHKGLGKA--EAFEESVKMLDAVKMPEARKRMRmfphEFSGGMRQRVMIA 180
Cdd:cd03234   82 cVAYVRQD--DILLPGLTVRETLtyTAILRLPRKSSDAirKKRVEDVLLRDLALTRIGGNLVK----GISGGERRRVSIA 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 556427173 181 MALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITH 227
Cdd:cd03234  156 VQLLWDPKVLILDEPTSGLDSFTALNLVSTLSQLARR-NRIVILTIH 201

ABCD_peroxisomal_ALDP

cd03223

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...

26-227

3.01e-19

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).

Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 83.36 E-value: 3.01e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  26 RVTFKTPDGDVTaVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLL-AANGVIGgsaKFNGREILNLPEHelnklrae 104
Cdd:cd03223    5 NLSLATPDGRVL-LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWpWGSGRIG---MPEGEDLLFLPQR-------- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 105 qismifqdpmtslnPYMRVGeQLMEVLMlhkglgkaeafeesvkmldavkmpearkrmrmFP--HEFSGGMRQRVMIAMA 182
Cdd:cd03223   73 --------------PYLPLG-TLREQLI--------------------------------YPwdDVLSGGEQQRLAFARL 105

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 556427173 183 LLCRPKLLIADEPTTALDVTVQAQIMTLLNELKrefnTAIIMITH 227
Cdd:cd03223  106 LLHKPKFVFLDEATSALDEESEDRLYQLLKELG----ITVISVGH 146

PRK03695

vitamin B12-transporter ATPase; Provisional

42-256

4.24e-19

vitamin B12-transporter ATPase; Provisional

Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 84.98 E-value: 4.24e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  42 LNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIggsaKFNGREILNLPEHELNKLRA---EQISMIFqdpmtsln 118
Cdd:PRK03695  15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLLPGSGSI----QFAGQPLEAWSAAELARHRAylsQQQTPPF-------- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 119 pymrvgeqLMEV---LMLHKGLGKAEAFEESV--KMLDAVKMPEARKRMrmfPHEFSGGMRQRVMIAMALL-----CRP- 187
Cdd:PRK03695  83 --------AMPVfqyLTLHQPDKTRTEAVASAlnEVAEALGLDDKLGRS---VNQLSGGEWQRVRLAAVVLqvwpdINPa 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 188 -KLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:PRK03695 152 gQLLLLDEPMNSLDVAQQAALDRLLSELCQQ-GIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEV 220

fecE

PRK11231

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

34-278

5.25e-19

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 85.07 E-value: 5.25e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELnklrAEQISMIFQDP 113
Cdd:PRK11231  13 GTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQS---GTVFLGDKPISMLSSRQL----ARRLALLPQHH 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 MT------------SLNPYM----RVG---EQLMEVLMlhkglGKAEAFEESVKMLDavkmpearkrmrmfphEFSGGMR 174
Cdd:PRK11231  86 LTpegitvrelvayGRSPWLslwgRLSaedNARVNQAM-----EQTRINHLADRRLT----------------DLSGGQR 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 175 QRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEYGKAR 254
Cdd:PRK11231 145 QRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQGKT-VVTVLHDLNQASRYCDHLVVLANGHVMAQGTPE 223

                        250       260
                 ....*....|....*....|....
gi 556427173 255 DVFYQpahpysiGLLNAVPRLDAE 278
Cdd:PRK11231 224 EVMTP-------GLLRTVFDVEAE 240

LptB

COG1137

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...

20-256

9.68e-19

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 83.93 E-value: 9.68e-19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFKtpdgDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHEln 99
Cdd:COG1137    4 LEAENLVKSYG----KRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDS---GRIFLDGEDITHLPMHK-- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 klRA-------EQISMIFQDpMTslnpymrVGEQLMEVLMLHKgLGKAEAFEESVKMLDAVKMPEARKRMRMfphEFSGG 172
Cdd:COG1137   75 --RArlgigylPQEASIFRK-LT-------VEDNILAVLELRK-LSKKEREERLEELLEEFGITHLRKSKAY---SLSGG 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 173 MRQRVMIAMALLCRPKLLIADEPTTALD-VTVqAQIMTLLNELKrEFNTAIImIT-HD----LgvvaGICDKVLVMYAGR 246
Cdd:COG1137  141 ERRRVEIARALATNPKFILLDEPFAGVDpIAV-ADIQKIIRHLK-ERGIGVL-ITdHNvretL----GICDRAYIISEGK 213

                        250
                 ....*....|
gi 556427173 247 TMEYGKARDV 256
Cdd:COG1137  214 VLAEGTPEEI 223

ModF

COG1119

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...

19-257

1.34e-18

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];

Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 83.60 E-value: 1.34e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLaaNGVI----GGSAKFNGREilnLP 94
Cdd:COG1119    3 LLELRNVTVRR----GGKTILDDISWTVKPGEHWAILGPNGAGKS----TLLSLI--TGDLpptyGNDVRLFGER---RG 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  95 EHELNKLRAeQI---SMIFQDpmtslnpYMRVGEQLMEVLM--LHKGLG-----KAEAFEESVKMLDAVKMpeARKRMRM 164
Cdd:COG1119   70 GEDVWELRK-RIglvSPALQL-------RFPRDETVLDVVLsgFFDSIGlyrepTDEQRERARELLELLGL--AHLADRP 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 165 FpHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLG-VVAGIcDKVLVMY 243
Cdd:COG1119  140 F-GTLSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEeIPPGI-THVLLLK 217

                        250
                 ....*....|....
gi 556427173 244 AGRTMEYGKARDVF 257
Cdd:COG1119  218 DGRVVAAGPKEEVL 231

thiQ

PRK10771

thiamine ABC transporter ATP-binding protein ThiQ;

43-246

1.55e-18

thiamine ABC transporter ATP-binding protein ThiQ;

Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 83.09 E-value: 1.55e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  43 NFNLRAGETLGIVGESGSGKSqTAFALM-GLLAANGviggsakfnGREILNLPEHELNKLRAEQISMIFQDpmTSLNPYM 121
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKS-TLLNLIaGFLTPAS---------GSLTLNGQDHTTTPPSRRPVSMLFQE--NNLFSHL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 122 RVGEQLmeVLMLHKGLGKAEAFEESVK-MLDAVKMPEARKRmrmFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALD 200
Cdd:PRK10771  87 TVAQNI--GLGLNPGLKLNAAQREKLHaIARQMGIEDLLAR---LPGQLSGGQRQRVALARCLVREQPILLLDEPFSALD 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 556427173 201 VTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PRK10771 162 PALRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGR 207

modC

PRK11144

molybdenum ABC transporter ATP-binding protein ModC;

13-264

1.59e-18

molybdenum ABC transporter ATP-binding protein ModC;

Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 84.93 E-value: 1.59e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  13 QQQNNLLLDVK-DLrvtfktPDGDVTAvndlnfnlragetlgIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGReIL 91
Cdd:PRK11144   8 QQLGDLCLTVNlTL------PAQGITA---------------IFGRSGAGKTSLINAISGLTRPQK---GRIVLNGR-VL 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  92 NLPEHELNkLRAEQ--ISMIFQDpmTSLNPYMRV-GEqlmevlmLHKGLGK--AEAFEESVKMLDAVKMpearkrMRMFP 166
Cdd:PRK11144  63 FDAEKGIC-LPPEKrrIGYVFQD--ARLFPHYKVrGN-------LRYGMAKsmVAQFDKIVALLGIEPL------LDRYP 126

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 167 HEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PRK11144 127 GSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGK 206

                        250
                 ....*....|....*....
gi 556427173 247 TMEYGKARDVFYQPA-HPY 264
Cdd:PRK11144 207 VKAFGPLEEVWASSAmRPW 225

PRK11176

lipid A ABC transporter ATP-binding protein/permease MsbA;

20-251

1.75e-18

lipid A ABC transporter ATP-binding protein/permease MsbA;

Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 86.23 E-value: 1.75e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDlrVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGreiLNLPEHELN 99
Cdd:PRK11176 342 IEFRN--VTFTYPGKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDE---GEILLDG---HDLRDYTLA 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRaEQISMI------FQDPMTSLNPYMRvgeqlmevlmlhKGLGKAEAFEESVKMLDAV----KMPEARKRMrmfPHE- 168
Cdd:PRK11176 414 SLR-NQVALVsqnvhlFNDTIANNIAYAR------------TEQYSREQIEEAARMAYAMdfinKMDNGLDTV---IGEn 477

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 169 ---FSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAGiCDKVLVMYAG 245
Cdd:PRK11176 478 gvlLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQK--NRTSLVIAHRLSTIEK-ADEILVVEDG 554


                 ....*.
gi 556427173 246 RTMEYG 251
Cdd:PRK11176 555 EIVERG 560

PRK13536

nodulation factor ABC transporter ATP-binding protein NodI;

4-256

4.23e-18

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 83.73 E-value: 4.23e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   4 IETATAPQAQQQNNLLLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAN-GVIggs 82
Cdd:PRK13536  26 ISEAKASIPGSMSTVAIDLAGVSKSY----GDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDaGKI--- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  83 akfngrEILNLPEHELNKLRAEQISMIFQdpMTSLNPYMRVGEQLMeVLMLHKGLgKAEAFEESVKMLDAVKMPEARKRM 162
Cdd:PRK13536  99 ------TVLGVPVPARARLARARIGVVPQ--FDNLDLEFTVRENLL-VFGRYFGM-STREIEAVIPSLLEFARLESKADA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 163 RMfpHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVM 242
Cdd:PRK13536 169 RV--SDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSLLARGKT-ILLTTHFMEEAERLCDRLCVL 245

                        250
                 ....*....|....
gi 556427173 243 YAGRTMEYGKARDV 256
Cdd:PRK13536 246 EAGRKIAEGRPHAL 259

3a01208

TIGR00958

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

27-252

4.59e-18

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 85.16 E-value: 4.59e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   27 VTFKTPD-GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELNKlraeQ 105
Cdd:TIGR00958 484 VSFSYPNrPDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTG---GQVLLDGVPLVQYDHHYLHR----Q 556

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  106 ISMIFQDPmtslnpymrvgeqlmeVLM---LHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPHEF-----------SG 171
Cdd:TIGR00958 557 VALVGQEP----------------VLFsgsVRENIAYGLTDTPDEEIMAAAKAANAHDFIMEFPNGYdtevgekgsqlSG 620

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  172 GMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAqimtLLNELKREFNTAIIMITHDLGVVAGiCDKVLVMYAGRTMEYG 251
Cdd:TIGR00958 621 GQKQRIAIARALVRKPRVLILDEATSALDAECEQ----LLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMG 695


                  .
gi 556427173  252 K 252
Cdd:TIGR00958 696 T 696

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

35-255

7.39e-18

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 84.07 E-value: 7.39e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  35 DVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGllaANGVIGGSAKFNGREILnlPEHELNKLRaEQISMIFQD-- 112
Cdd:PRK09700 275 DRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFG---VDKRAGGEIRLNGKDIS--PRSPLDAVK-KGMAYITESrr 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 113 -----PMTSLNPYMRVGEQLMEvlmlhKGLGKAEA-FEESVKMLDAvkmPEARKRMRMFPH-------EFSGGMRQRVMI 179
Cdd:PRK09700 349 dngffPNFSIAQNMAISRSLKD-----GGYKGAMGlFHEVDEQRTA---ENQRELLALKCHsvnqnitELSGGNQQKVLI 420

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556427173 180 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARD 255
Cdd:PRK09700 421 SKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADD-GKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRD 495

cbiO

PRK13649

energy-coupling factor transporter ATPase;

38-257

7.71e-18

energy-coupling factor transporter ATPase;

Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 82.10 E-value: 7.71e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  38 AVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELNKLRAEQISMIFQDPMTsl 117
Cdd:PRK13649  22 ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQ---GSVRVDDTLITSTSKNKDIKQIRKKVGLVFQFPES-- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 118 npymrvgeQLMEVLMLhkglgKAEAFEES---VKMLDAVKMpeARKRMRMF----------PHEFSGGMRQRVMIAMALL 184
Cdd:PRK13649  97 --------QLFEETVL-----KDVAFGPQnfgVSQEEAEAL--AREKLALVgiseslfeknPFELSGGQMRRVAIAGILA 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173 185 CRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVF 257
Cdd:PRK13649 162 MEPKILVLDEPTAGLDPKGRKELMTLFKKLHQSGMT-IVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIF 233

PRK15056

manganese/iron ABC transporter ATP-binding protein;

22-257

7.98e-18

manganese/iron ABC transporter ATP-binding protein;

Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 81.85 E-value: 7.98e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  22 VKDLRVTFKTPDgdvTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLL-AANGVIGgsakfngreILNLPEHElnK 100
Cdd:PRK15056   9 VNDVTVTWRNGH---TALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVrLASGKIS---------ILGQPTRQ--A 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 101 LRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGL---GKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQRV 177
Cdd:PRK15056  75 LQKNLVAYVPQSEEVDWSFPVLVEDVVMMGRYGHMGWlrrAKKRDRQIVTAALARVDMVEFRHRQ---IGELSGGQKKRV 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMiTHDLGVVAGICDKVlVMYAGRTMEYGKARDVF 257
Cdd:PRK15056 152 FLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDEGKTMLVS-THNLGSVTEFCDYT-VMVKGTVLASGPTETTF 229

PRK13537

nodulation factor ABC transporter ATP-binding protein NodI;

20-256

1.08e-17

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 82.16 E-value: 1.08e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlnlPEHEln 99
Cdd:PRK13537   8 IDFRNVEKRY----GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDA---GSISLCGEPV---PSRA-- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRAEQISMIFQdpMTSLNPYMRVGEQLMeVLMLHKGLGKAEAFEESVKMLDAVKMpEARKRMRMfpHEFSGGMRQRVMI 179
Cdd:PRK13537  76 RHARQRVGVVPQ--FDNLDPDFTVRENLL-VFGRYFGLSAAAARALVPPLLEFAKL-ENKADAKV--GELSGGMKRRLTL 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 180 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:PRK13537 150 ARALVNDPDVLVLDEPTTGLDPQARHLMWERLRSLLARGKT-ILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHAL 225

anch_rpt_ABC

TIGR03771

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...

44-242

1.12e-17

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]

Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 80.67 E-value: 1.12e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   44 FNLRAGETLGIVGESGSGKSQTAFALMGLLA-ANGVI---GGSAKFNGREILNLPE-HELN---KLRAEQISMIFQDPMT 115
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPpAKGTVkvaGASPGKGWRHIGYVPQrHEFAwdfPISVAHTVMSGRTGHI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  116 SLNPYMRVGEqlmevlmlHKGLGKAeafeesvkmLDAVKMPEARKRmrmfP-HEFSGGMRQRVMIAMALLCRPKLLIADE 194
Cdd:TIGR03771  81 GWLRRPCVAD--------FAAVRDA---------LRRVGLTELADR----PvGELSGGQRQRVLVARALATRPSVLLLDE 139

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 556427173  195 PTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVM 242
Cdd:TIGR03771 140 PFTGLDMPTQELLTELFIELAGA-GTAILMTTHDLAQAMATCDRVVLL 186

ABC_ThiQ_thiamine_transporter

cd03298

ATP-binding cassette domain of the thiamine transport system; Part of the ...

41-246

1.32e-17

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 80.23 E-value: 1.32e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  41 DLNFNLRAGETLGIVGESGSGKSqtafALMGLLAangviGGSAKFNGREILNLPEHELNKLRAEQISMIFQDpmTSLNPY 120
Cdd:cd03298   16 HFDLTFAQGEITAIVGPSGSGKS----TLLNLIA-----GFETPQSGRVLINGVDVTAAPPADRPVSMLFQE--NNLFAH 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 121 MRVGEQLmeVLMLHKGLGKAEAFEESVKMLdAVKMPEARKRMRMfPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALD 200
Cdd:cd03298   85 LTVEQNV--GLGLSPGLKLTAEDRQAIEVA-LARVGLAGLEKRL-PGELSGGERQRVALARVLVRDKPVLLLDEPFAALD 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 556427173 201 VTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:cd03298  161 PALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGR 206

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

34-233

1.74e-17

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 79.20 E-value: 1.74e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngVIGGSAKFNGREILNLPEHelnklraeqISMIFQDP 113
Cdd:NF040873   3 GGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRP--TSGTVRRAGGARVAYVPQR---------SEVPDSLP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 MTSlnpymrvgEQLMEV-LMLHKGLGK---AEAFEESVKMLDAVKMPEARKRMRmfpHEFSGGMRQRVMIAMALLCRPKL 189
Cdd:NF040873  72 LTV--------RDLVAMgRWARRGLWRrltRDDRAAVDDALERVGLADLAGRQL---GELSGGQRQRALLAQGLAQEADL 140

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 556427173 190 LIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVA 233
Cdd:NF040873 141 LLLDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVR 183

PLN03211

ABC transporter G-25; Provisional

49-280

4.89e-17

ABC transporter G-25; Provisional

Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 81.85 E-value: 4.89e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  49 GETLGIVGESGSGKSQTAFALMGLLAANGVIGgSAKFNGREIlnlpehelNKLRAEQISMIFQDPMtsLNPYMRVGEQLM 128
Cdd:PLN03211  94 GEILAVLGPSGSGKSTLLNALAGRIQGNNFTG-TILANNRKP--------TKQILKRTGFVTQDDI--LYPHLTVRETLV 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 129 --EVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRM--RMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQ 204
Cdd:PLN03211 163 fcSLLRLPKSLTKQEKILVAESVISELGLTKCENTIigNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAA 242

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 205 AQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARD-------VFYQPAHP-----YSIGLLNAV 272
Cdd:PLN03211 243 YRLVLTLGSLAQKGKTIVTSMHQPSSRVYQMFDSVLVLSEGRCLFFGKGSDamayfesVGFSPSFPmnpadFLLDLANGV 322


                 ....*...
gi 556427173 273 PRLDAEGE 280
Cdd:PLN03211 323 CQTDGVSE 330

PRK11160

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

11-252

5.02e-17

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 81.79 E-value: 5.02e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  11 QAQQQNNLLLDVKDlrVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAAN-GVIGGSAKFNGRE 89
Cdd:PRK11160 330 STAAADQVSLTLNN--VSFTYPDQPQPVLKGLSLQIKAGEKVALLGRTGCGKS----TLLQLLTRAwDPQQGEILLNGQP 403

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  90 ILNLPEHELnklRAeQISMIFQDP---MTSLNPYMRVG------EQLMEVLMlHKGLGKaeaFEESVKMLDAVKMPEARk 160
Cdd:PRK11160 404 IADYSEAAL---RQ-AISVVSQRVhlfSATLRDNLLLAapnasdEALIEVLQ-QVGLEK---LLEDDKGLNAWLGEGGR- 474

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 161 rmrmfphEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAGIcDKVL 240
Cdd:PRK11160 475 -------QLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQ--NKTVLMITHRLTGLEQF-DRIC 544

                        250
                 ....*....|..
gi 556427173 241 VMYAGRTMEYGK 252
Cdd:PRK11160 545 VMDNGQIIEQGT 556

cbiO

PRK13644

energy-coupling factor transporter ATPase;

26-282

6.28e-17

energy-coupling factor transporter ATPase;

Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 79.65 E-value: 6.28e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  26 RVTFKTPDGdVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANgviGGSAKFNGREILNLPE-HELNKLrae 104
Cdd:PRK13644   6 NVSYSYPDG-TPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQ---KGKVLVSGIDTGDFSKlQGIRKL--- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 105 qISMIFQDPMTSLnpymrVGEQLMEVLML---HKGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQRVMIAM 181
Cdd:PRK13644  79 -VGIVFQNPETQF-----VGRTVEEDLAFgpeNLCLPPIEIRKRVDRALAEIGLEKYRHRS---PKTLSGGQGQCVALAG 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 182 ALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAgICDKVLVMYAGRTMEYGKARDVFYQPA 261
Cdd:PRK13644 150 ILTMEPECLIFDEVTSMLDPDSGIAVLERIKKLHEKGKT-IVYITHNLEELH-DADRIIVMDRGKIVLEGEPENVLSDVS 227

                        250       260
                 ....*....|....*....|.
gi 556427173 262 HPYsIGLlnAVPRLDAEGESL 282
Cdd:PRK13644 228 LQT-LGL--TPPSLIELAENL 245

PRK13651

cobalt transporter ATP-binding subunit; Provisional

22-256

8.60e-17

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 79.36 E-value: 8.60e-17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  22 VKDLRVTF--KTPDgDVTAVNDLNFNLRAGETLGIVGESGSGKsqTAF-----ALmgLLAANGVI-------------GG 81
Cdd:PRK13651   5 VKNIVKIFnkKLPT-ELKALDNVSVEINQGEFIAIIGQTGSGK--TTFiehlnAL--LLPDTGTIewifkdeknkkktKE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  82 SAKFNGREILNLPEHE----LNKLRaEQISMIFQdpmtsLNPYMRVGEQLMEVLM---LHKGLGKAEAFEESVKMLDAVK 154
Cdd:PRK13651  80 KEKVLEKLVIQKTRFKkikkIKEIR-RRVGVVFQ-----FAEYQLFEQTIEKDIIfgpVSMGVSKEEAKKRAAKYIELVG 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 155 MPEARkrMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAG 234
Cdd:PRK13651 154 LDESY--LQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKT-IILVTHDLDNVLE 230

                        250       260
                 ....*....|....*....|..
gi 556427173 235 ICDKVLVMYAGRTMEYGKARDV 256
Cdd:PRK13651 231 WTKRTIFFKDGKIIKDGDTYDI 252

ATM1

COG5265

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...

5-251

1.24e-16

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 80.63 E-value: 1.24e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   5 ETATAPQAQQqnnllLDVKDLRVTFK----TPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvig 80
Cdd:COG5265  341 EVADAPDAPP-----LVVGGGEVRFEnvsfGYDPERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTS--- 412

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  81 GSAKFNGREILNLPEHELnklRAeQISMIFQDpmTSL-------N-PYmrvgeqlmevlmlhkglGKAEAFEESVkmLDA 152
Cdd:COG5265  413 GRILIDGQDIRDVTQASL---RA-AIGIVPQD--TVLfndtiayNiAY-----------------GRPDASEEEV--EAA 467

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 153 VKMPEArkrmrmfpHEF-------------------SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNE 213
Cdd:COG5265  468 ARAAQI--------HDFieslpdgydtrvgerglklSGGEKQRVAIARTLLKNPPILIFDEATSALDSRTERAIQAALRE 539

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 556427173 214 LKRefNTAIIMITHDLGVVAGiCDKVLVMYAGRTMEYG 251
Cdd:COG5265  540 VAR--GRTTLVIAHRLSTIVD-ADEILVLEAGRIVERG 574

PRK14258

phosphate ABC transporter ATP-binding protein; Provisional

53-260

1.49e-16

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 78.15 E-value: 1.49e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  53 GIVGESGSGKSQTAFAL--MGLLAANGVIGGSAKFNGREILNlPEHELNKLRaEQISMIFQDPmtSLNPyMRVGEQL--- 127
Cdd:PRK14258  37 AIIGPSGCGKSTFLKCLnrMNELESEVRVEGRVEFFNQNIYE-RRVNLNRLR-RQVSMVHPKP--NLFP-MSVYDNVayg 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 128 MEVLMLHKGLGKAEAFEESVKmlDAVKMPEARKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQI 207
Cdd:PRK14258 112 VKIVGWRPKLEIDDIVESALK--DADLWDEIKHKIHKSALDLSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKV 189

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 208 MTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYA-----GRTMEYGKARDVFYQP 260
Cdd:PRK14258 190 ESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTKKIFNSP 247

3a01204

TIGR00955

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...

46-263

1.93e-16

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 80.09 E-value: 1.93e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   46 LRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKFNGREIlnlpehELNKLRAeqIS-MIFQDPMtsLNPYMRVG 124
Cdd:TIGR00955  48 AKPGELLAVMGSSGAGKTTLMNALAFRSPKGVKGSGSVLLNGMPI------DAKEMRA--ISaYVQQDDL--FIPTLTVR 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  125 EQLMEVLML--HKGLGKAEAFEESVKMLDAVKMPEARK-------RMRmfphEFSGGMRQRVMIAMALLCRPKLLIADEP 195
Cdd:TIGR00955 118 EHLMFQAHLrmPRRVTKKEKRERVDEVLQALGLRKCANtrigvpgRVK----GLSGGERKRLAFASELLTDPPLLFCDEP 193

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556427173  196 TTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGK---ARDVFYQPAHP 263
Cdd:TIGR00955 194 TSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAEGRVAYLGSpdqAVPFFSDLGHP 264

cbiO

PRK13643

energy-coupling factor transporter ATPase;

38-259

2.92e-16

energy-coupling factor transporter ATPase;

Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 77.85 E-value: 2.92e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  38 AVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELNKLRAEQISMIFQDPMTsl 117
Cdd:PRK13643  21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTE---GKVTVGDIVVSSTSKQKEIKPVRKKVGVVFQFPES-- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 118 npymrvgeQLMEVLMLHK--------GLGKAEAFEESVKMLDAVKMpeARKRMRMFPHEFSGGMRQRVMIAMALLCRPKL 189
Cdd:PRK13643  96 --------QLFEETVLKDvafgpqnfGIPKEKAEKIAAEKLEMVGL--ADEFWEKSPFELSGGQMRRVAIAGILAMEPEV 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 190 LIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQ 259
Cdd:PRK13643 166 LVLDEPTAGLDPKARIEMMQLFESIHQSGQT-VVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQE 234

PRK10895

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

37-257

5.44e-16

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 76.09 E-value: 5.44e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  37 TAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHElnklRAEQ-ISMIFQDPmt 115
Cdd:PRK10895  17 RVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDA---GNIIIDDEDISLLPLHA----RARRgIGYLPQEA-- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 116 SLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQRVMIAMALLCRPKLLIADEP 195
Cdd:PRK10895  88 SIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSM---GQSLSGGERRRVEIARALAANPKFILLDEP 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556427173 196 TTALDVTVQAQIMTLLNELkREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVF 257
Cdd:PRK10895 165 FAGVDPISVIDIKRIIEHL-RDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEIL 225

PRK11000

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

34-269

5.54e-16

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 77.76 E-value: 5.54e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLlaaNGVIGGSAKFNGREILNLPEHELNklraeqISMIFQDp 113
Cdd:PRK11000  14 GDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGL---EDITSGDLFIGEKRMNDVPPAERG------VGMVFQS- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 mTSLNPYMRVGEQLMEVLMLhKGLGKAEA---FEESVKMLDAVKMPEARkrmrmfPHEFSGGMRQRVMIAMALLCRPKLL 190
Cdd:PRK11000  84 -YALYPHLSVAENMSFGLKL-AGAKKEEInqrVNQVAEVLQLAHLLDRK------PKALSGGQRQRVAIGRTLVAEPSVF 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 191 IADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPAHPYSIGLL 269
Cdd:PRK11000 156 LLDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANRFVAGFI 234

GguA

NF040905

sugar ABC transporter ATP-binding protein;

19-249

6.21e-16

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 78.29 E-value: 6.21e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLA---ANGVIGGSAKFNGREIlnlpe 95
Cdd:NF040905   1 ILEMRGITKTF----PGVKALDDVNLSVREGEIHALCGENGAGKS----TLMKVLSgvyPHGSYEGEILFDGEVC----- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  96 hELNKLRA-EQ--ISMIFQDpmTSLNPYMRVGEQLMevlmlhkgLGK----------AEAFEESVKMLDAVKMPEArkrm 162
Cdd:NF040905  68 -RFKDIRDsEAlgIVIIHQE--LALIPYLSIAENIF--------LGNerakrgvidwNETNRRARELLAKVGLDES---- 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 163 rmfPHEFSG----GMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIImITHDLGVVAGICDK 238
Cdd:NF040905 133 ---PDTLVTdigvGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSII-ISHKLNEIRRVADS 208

                        250
                 ....*....|.
gi 556427173 239 VLVMYAGRTME 249
Cdd:NF040905 209 ITVLRDGRTIE 219

ABCC_TAP

cd03248

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...

22-246

6.56e-16

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.

Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 75.59 E-value: 6.56e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  22 VKDLRVTFKTPD-GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlNLPEHelnK 100
Cdd:cd03248   12 VKFQNVTFAYPTrPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQG---GQVLLDGKPI-SQYEH---K 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 101 LRAEQISMIFQDPMT---SLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMfphefSGGMRQRV 177
Cdd:cd03248   85 YLHSKVSLVGQEPVLfarSLQDNIAYGLQSCSFECVKEAAQKAHAHSFISELASGYDTEVGEKGSQL-----SGGQKQRV 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAGiCDKVLVMYAGR 246
Cdd:cd03248  160 AIARALIRNPQVLILDEATSALDAESEQQVQQALYDWPE--RRTVLVIAHRLSTVER-ADQILVLDGGR 225

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

38-246

6.59e-16

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 78.23 E-value: 6.59e-16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  38 AVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREILNLPEHE-LNK---LRAEQ-------- 105
Cdd:PRK10982 263 SIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREK---SAGTITLHGKKINNHNANEaINHgfaLVTEErrstgiya 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 106 -ISMIFQDPMTSLNPYMRvgeqlmevlmlHKGLGKAEAFEESVK-MLDA--VKMPEARKRMrmfpHEFSGGMRQRVMIAM 181
Cdd:PRK10982 340 yLDIGFNSLISNIRNYKN-----------KVGLLDNSRMKSDTQwVIDSmrVKTPGHRTQI----GSLSGGNQQKVIIGR 404

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 182 ALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PRK10982 405 WLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKK-DKGIIIISSEMPELLGITDRILVMSNGL 468

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

20-256

1.03e-15

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 77.92 E-value: 1.03e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   20 LDVKDLRVTFKtpdgDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAN----------------------- 76
Cdd:TIGR03269   1 IEVKNLTKKFD----GKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQYEptsgriiyhvalcekcgyverps 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   77 ------GVIGGSAKFNGREILNLPEHELNKLRaEQISMIFQDPMtSLNPYMRVGEQLMEVLMlHKGLGKAEAFEESVKML 150
Cdd:TIGR03269  77 kvgepcPVCGGTLEPEEVDFWNLSDKLRRRIR-KRIAIMLQRTF-ALYGDDTVLDNVLEALE-EIGYEGKEAVGRAVDLI 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  151 DAVKMPEarkRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLG 230
Cdd:TIGR03269 154 EMVQLSH---RITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPE 230

                         250       260
                  ....*....|....*....|....*.
gi 556427173  231 VVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:TIGR03269 231 VIEDLSDKAIWLENGEIKEEGTPDEV 256

CeuD

COG4604

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...

34-256

1.34e-15

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 75.12 E-value: 1.34e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMG-LLAANGvigGSAKFNGREILNLPEHELnklrAEQISMIFQD 112
Cdd:COG4604   12 GGKVVLDDVSLTIPKGGITALIGPNGAGKS-TLLSMISrLLPPDS---GEVLVDGLDVATTPSREL----AKRLAILRQE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 113 PmtSLNPYMRVGEqlmevlmL--------HKGLGKAEafeesvkmlDAVKMPEARKRMRM------FPHEFSGGMRQRVM 178
Cdd:COG4604   84 N--HINSRLTVRE-------LvafgrfpySKGRLTAE---------DREIIDEAIAYLDLedladrYLDELSGGQRQRAF 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 179 IAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:COG4604  146 IAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEI 223

PRK11831

phospholipid ABC transporter ATP-binding protein MlaF;

12-256

1.48e-15

phospholipid ABC transporter ATP-binding protein MlaF;

Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 75.57 E-value: 1.48e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  12 AQQQNNLLlDVKDLRVTfktpDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGllaanGVI---GGSAKFNGR 88
Cdd:PRK11831   1 EQSVANLV-DMRGVSFT----RGNRCIFDNISLTVPRGKITAIMGPSGIGKT-TLLRLIG-----GQIapdHGEILFDGE 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  89 EILNLPEHELNKLRaEQISMIFQDP--MTSLNPYMRVGEQLMEvlmlHKGLgKAEAFEESVKM-LDAVKMPEARKRMrmf 165
Cdd:PRK11831  70 NIPAMSRSRLYTVR-KRMSMLFQSGalFTDMNVFDNVAYPLRE----HTQL-PAPLLHSTVMMkLEAVGLRGAAKLM--- 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 166 PHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAG 245
Cdd:PRK11831 141 PSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADK 220

                        250
                 ....*....|.
gi 556427173 246 RTMEYGKARDV 256
Cdd:PRK11831 221 KIVAHGSAQAL 231

ugpC

PRK11650

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

20-261

2.66e-15

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 75.65 E-value: 2.66e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRvtfKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAA-NGVIGGSAKFNGREILNLPEHEL 98
Cdd:PRK11650   4 LKLQAVR---KSYDGKTQVIKGIDLDVADGEFIVLVGPSGCGKS----TLLRMVAGlERITSGEIWIGGRVVNELEPADR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 NklraeqISMIFQDpmTSLNPYMRVgEQLMEVLMLHKGLGKAEA---FEESVKMLDAVKMPEaRKrmrmfPHEFSGGMRQ 175
Cdd:PRK11650  77 D------IAMVFQN--YALYPHMSV-RENMAYGLKIRGMPKAEIeerVAEAARILELEPLLD-RK-----PRELSGGQRQ 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 176 RVMIAMALLCRPKLLIADEPTTALDVTVQAQiMTL-LNELKREFNTAIIMITHD------LGvvagicDKVLVMYAGRTM 248
Cdd:PRK11650 142 RVAMGRAIVREPAVFLFDEPLSNLDAKLRVQ-MRLeIQRLHRRLKTTSLYVTHDqveamtLA------DRVVVMNGGVAE 214

                        250
                 ....*....|...
gi 556427173 249 EYGKARDVFYQPA 261
Cdd:PRK11650 215 QIGTPVEVYEKPA 227

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

10-250

4.69e-15

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 75.87 E-value: 4.69e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  10 PQAQQQNNLLLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAF-ALMGLLAANGvigGSAKFnGR 88
Cdd:COG0488  306 PPPERLGKKVLELEGLSKSY----GDKTLLDDLSLRIDRGDRIGLIGPNGAGKS-TLLkLLAGELEPDS---GTVKL-GE 376

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  89 EIlnlpehelnklraeQISMIFQDpMTSLNPYMRVGEQLMEvlmlhkglGKAEAFEESV-----KML---DavkmpEARK 160
Cdd:COG0488  377 TV--------------KIGYFDQH-QEELDPDKTVLDELRD--------GAPGGTEQEVrgylgRFLfsgD-----DAFK 428

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 161 RMRmfphEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDV-TVQAqimtlLNELKREFNTAIIMITHDLGVVAGICDKV 239
Cdd:COG0488  429 PVG----VLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIeTLEA-----LEEALDDFPGTVLLVSHDRYFLDRVATRI 499

                        250
                 ....*....|.
gi 556427173 240 LVMYAGRTMEY 250
Cdd:COG0488  500 LEFEDGGVREY 510

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

22-228

6.01e-15

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 75.49 E-value: 6.01e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  22 VKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTafaLMGLLAanGVI---GGSAKFNGR--------EI 90
Cdd:COG0488    1 LENLSKSF----GGRPLLDDVSLSINPGDRIGLVGRNGAGKS-T---LLKILA--GELepdSGEVSIPKGlrigylpqEP 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  91 LNLPEH-----------ELNKLRAE--QISMIFQDPMTSLNPYMRVGEQLME---------VLMLHKGLG-KAEAFEESV 147
Cdd:COG0488   71 PLDDDLtvldtvldgdaELRALEAEleELEAKLAEPDEDLERLAELQEEFEAlggweaearAEEILSGLGfPEEDLDRPV 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 148 KmldavkmpearkrmrmfphEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDvtVQAqIMTLLNELKReFNTAIIMITH 227
Cdd:COG0488  151 S-------------------ELSGGWRRRVALARALLSEPDLLLLDEPTNHLD--LES-IEWLEEFLKN-YPGTVLVVSH 207


                 .
gi 556427173 228 D 228
Cdd:COG0488  208 D 208

GguA

NF040905

sugar ABC transporter ATP-binding protein;

39-246

6.90e-15

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 75.21 E-value: 6.90e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  39 VNDLNFNLRAGETLGIVGESGSGKSQTAFALMGllAANGV-IGGSAKFNGREI------------------------LNL 93
Cdd:NF040905 276 VDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFG--RSYGRnISGTVFKDGKEVdvstvsdaidaglayvtedrkgygLNL 353

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  94 PEHelnkLRaEQISMifqdpmTSLNPYMRVGeqlmeVLMLHKGLGKAEAFeesvkmldavkmpeaRKRMRMFPH------ 167
Cdd:NF040905 354 IDD----IK-RNITL------ANLGKVSRRG-----VIDENEEIKVAEEY---------------RKKMNIKTPsvfqkv 402

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 168 -EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:NF040905 403 gNLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGVIVISSELPELLGMCDRIYVMNEGR 481

PTZ00243

ABC transporter; Provisional

6-277

9.99e-15

ABC transporter; Provisional

Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 75.20 E-value: 9.99e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173    6 TATAPQAQQQNNLLLDVKDLRVTfktpDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAangVIGGSAKF 85
Cdd:PTZ00243 1297 TSAAPHPVQAGSLVFEGVQMRYR----EGLPLVLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVE---VCGGEIRV 1369

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   86 NGREIlnlPEHELNKLRaEQISMIFQDPM-------TSLNPYMRVGEQlmEVLMLHKGLGKAEAFEESVKMLDAvkmpea 158
Cdd:PTZ00243 1370 NGREI---GAYGLRELR-RQFSMIPQDPVlfdgtvrQNVDPFLEASSA--EVWAALELVGLRERVASESEGIDS------ 1437

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  159 rkRMRMFPHEFSGGMRQRVMIAMALLCRPKLLI-ADEPTT----ALDVTVQAQIMTLLNelkrefNTAIIMITHDLGVVA 233
Cdd:PTZ00243 1438 --RVLEGGSNYSVGQRQLMCMARALLKKGSGFIlMDEATAnidpALDRQIQATVMSAFS------AYTVITIAHRLHTVA 1509

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 556427173  234 GiCDKVLVMYAGRTMEYGKARDVFYQPAHPYSiGLLNAVPRLDA 277
Cdd:PTZ00243 1510 Q-YDKIIVMDHGAVAEMGSPRELVMNRQSIFH-SMVEALGRSEA 1551

ABCF_EF-3

cd03221

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...

20-242

1.40e-14

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.

Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 69.78 E-value: 1.40e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafalmgllaangviggsakfngreilnlpeheln 99
Cdd:cd03221    1 IELENLSKTY----GGKLLLKDISLTINPGDRIGLVGRNGAGKS------------------------------------ 40

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 klraeqismifqdpmTslnpymrvgeqLMEVLMlhkglGKAEAFEESVKMLDAVKMPearkrmrMFPHeFSGGMRQRVMI 179
Cdd:cd03221   41 ---------------T-----------LLKLIA-----GELEPDEGIVTWGSTVKIG-------YFEQ-LSGGEKMRLAL 81

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556427173 180 AMALLCRPKLLIADEPTTALDV-TVQAqimtLLNELKrEFNTAIIMITHDLGVVAGICDKVLVM 242
Cdd:cd03221   82 AKLLLENPNLLLLDEPTNHLDLeSIEA----LEEALK-EYPGTVILVSHDRYFLDQVATKIIEL 140

PRK14243

phosphate transporter ATP-binding protein; Provisional

10-262

1.64e-14

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 72.51 E-value: 1.64e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  10 PQAQQQNNLLLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQT--AFALMGLLAANGVIGGSAKFNG 87
Cdd:PRK14243   1 TSTLNGTETVLRTENLNVYY----GSFLAVKNVWLDIPKNQITAFIGPSGCGKSTIlrCFNRLNDLIPGFRVEGKVTFHG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  88 REiLNLPEHELNKLRaEQISMIFQDPmtslNPYMR-------VGEQLMEvlmlHKGlGKAEAFEESVKmlDAVKMPEARK 160
Cdd:PRK14243  77 KN-LYAPDVDPVEVR-RRIGMVFQKP----NPFPKsiydniaYGARING----YKG-DMDELVERSLR--QAALWDEVKD 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 161 RMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFntAIIMITHDLGVVAGICDKVL 240
Cdd:PRK14243 144 KLKQSGLSLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQY--TIIIVTHNMQQAARVSDMTA 221

                        250       260       270
                 ....*....|....*....|....*....|.
gi 556427173 241 VMYA---------GRTMEYGKARDVFYQPAH 262
Cdd:PRK14243 222 FFNVeltegggryGYLVEFDRTEKIFNSPQQ 252

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

34-256

1.68e-14

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 74.05 E-value: 1.68e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLA-ANGVIGGSAKFNGREILNLpEHelnKLRAEQ-ISMIFQ 111
Cdd:PRK09700  16 GPVHALKSVNLTVYPGEIHALLGENGAGKS----TLMKVLSgIHEPTKGTITINNINYNKL-DH---KLAAQLgIGIIYQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 112 -----DPMTSL-NPYmrVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMpeaRKRMRMFPHEFSGGMRQRVMIAMALLC 185
Cdd:PRK09700  88 elsviDELTVLeNLY--IGRHLTKKVCGVNIIDWREMRVRAAMMLLRVGL---KVDLDEKVANLSISHKQMLEIAKTLML 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556427173 186 RPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:PRK09700 163 DAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDV 232

ABCG_PDR_domain1

cd03233

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...

27-251

3.57e-14

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 70.37 E-value: 3.57e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFKTPDGDVTA--VNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKFNGreilnLPEHELNKLRAE 104
Cdd:cd03233    9 ISFTTGKGRSKIpiLKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNVSVEGDIHYNG-----IPYKEFAEKYPG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 105 QISMIFQDpmTSLNPYMRVgEQLMEVLMLHKGlgkaeafEESVKmldavkmpearkrmrmfphEFSGGMRQRVMIAMALL 184
Cdd:cd03233   84 EIIYVSEE--DVHFPTLTV-RETLDFALRCKG-------NEFVR-------------------GISGGERKRVSIAEALV 134

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 185 CRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVA-GICDKVLVMYAGRTMEYG 251
Cdd:cd03233  135 SRASVLCWDNSTRGLDSSTALEILKCIRTMADVLKTTTFVSLYQASDEIyDLFDKVLVLYEGRQIYYG 202

PRK09984

phosphonate ABC transporter ATP-binding protein;

38-245

6.87e-14

phosphonate ABC transporter ATP-binding protein;

Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 70.43 E-value: 6.87e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  38 AVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKFNGREILNLPE--HELNKLRAeQISMIFQdpmt 115
Cdd:PRK09984  19 ALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAGSHIELLGRTVQREGRlaRDIRKSRA-NTGYIFQ---- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 116 SLNPYMRVgeQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEA-----RKRMRMFPHE----FSGGMRQRVMIAMALLCR 186
Cdd:PRK09984  94 QFNLVNRL--SVLENVLI-GALGSTPFWRTCFSWFTREQKQRAlqaltRVGMVHFAHQrvstLSGGQQQRVAIARALMQQ 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 187 PKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAG 245
Cdd:PRK09984 171 AKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQG 229

PRK10247

putative ABC transporter ATP-binding protein YbbL; Provisional

14-261

1.31e-13

putative ABC transporter ATP-binding protein YbbL; Provisional

Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 68.97 E-value: 1.31e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  14 QQNNLLLDVKDlrVTFKTpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNL 93
Cdd:PRK10247   2 QENSPLLQLQN--VGYLA--GDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTS---GTLLFEGEDISTL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  94 PEHELNKlraeQISMIFQDPMTslnpymrVGEQLMEVLMLHKGL-GKAEAFEESVKMLDAVKMPEA--RKRMrmfpHEFS 170
Cdd:PRK10247  75 KPEIYRQ----QVSYCAQTPTL-------FGDTVYDNLIFPWQIrNQQPDPAIFLDDLERFALPDTilTKNI----AELS 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGiCDKVLVMyagrTMEY 250
Cdd:PRK10247 140 GGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDEINH-ADKVITL----QPHA 214

                        250
                 ....*....|.
gi 556427173 251 GKARDVFYQPA 261
Cdd:PRK10247 215 GEMQEARYELA 225

PRK10575

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

27-256

2.50e-13

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 69.05 E-value: 2.50e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  27 VTFKTPDGdvTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMG----------LLAANGVIGGSAKFNGREILNLPEh 96
Cdd:PRK10575  17 VSFRVPGR--TLLHPLSLTFPAGKVTGLIGHNGSGKS-TLLKMLGrhqppsegeiLLDAQPLESWSSKAFARKVAYLPQ- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  97 elnklraeqismifQDPMTSlnpymrvGEQLMEVLML-----HKGLGKAEAfEESVKMLDAVKMPEARKRMRMFPHEFSG 171
Cdd:PRK10575  93 --------------QLPAAE-------GMTVRELVAIgrypwHGALGRFGA-ADREKVEEAISLVGLKPLAHRLVDSLSG 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 172 GMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYG 251
Cdd:PRK10575 151 GERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQG 230


                 ....*
gi 556427173 252 KARDV 256
Cdd:PRK10575 231 TPAEL 235

PRK10253

iron-enterobactin ABC transporter ATP-binding protein;

34-256

2.59e-13

iron-enterobactin ABC transporter ATP-binding protein;

Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 68.86 E-value: 2.59e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREIlnlpEHELNKLRAEQISMIFQDP 113
Cdd:PRK10253  18 GKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTP---AHGHVWLDGEHI----QHYASKEVARRIGLLAQNA 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 MTSLNpyMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIAD 193
Cdd:PRK10253  91 TTPGD--ITVQELVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLD 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556427173 194 EPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:PRK10253 169 EPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEI 231

PRK10789

SmdA family multidrug ABC transporter permease/ATP-binding protein;

28-260

3.03e-13

SmdA family multidrug ABC transporter permease/ATP-binding protein;

Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 70.51 E-value: 3.03e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  28 TFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALmgLLAANGVIGGSAKFNGreiLNLPEHELNKLRAE--- 104
Cdd:PRK10789 320 QFTYPQTDHPALENVNFTLKPGQMLGICGPTGSGKS-TLLSL--IQRHFDVSEGDIRFHD---IPLTKLQLDSWRSRlav 393

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 105 --QISMIFQDPMTSlnpymrvgeqlmevlmlHKGLGKAEAFEESVKML--------DAVKMP-----EARKRMRMFphef 169
Cdd:PRK10789 394 vsQTPFLFSDTVAN-----------------NIALGRPDATQQEIEHVarlasvhdDILRLPqgydtEVGERGVML---- 452

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 170 SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfnTAIIMITHDLGVVAGiCDKVLVMYAGRTME 249
Cdd:PRK10789 453 SGGQKQRISIARALLLNAEILILDDALSAVDGRTEHQILHNLRQWGEG--RTVIISAHRLSALTE-ASEILVMQHGHIAQ 529

                        250
                 ....*....|.
gi 556427173 250 YGKARDVFYQP 260
Cdd:PRK10789 530 RGNHDQLAQQS 540

sufC

PRK09580

cysteine desulfurase ATPase component; Reviewed

19-251

8.12e-13

cysteine desulfurase ATPase component; Reviewed

Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 67.12 E-value: 8.12e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFKtpdgDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANgVIGGSAKFNGREILNLPEHEl 98
Cdd:PRK09580   1 MLSIKDLHVSVE----DKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDYE-VTGGTVEFKGKDLLELSPED- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  99 nklRA-EQISMIFQDPM------------TSLNPYMRVGEQlmEVLmlhKGLGKAEAFEESVKMLdavKMPEARkRMRMF 165
Cdd:PRK09580  75 ---RAgEGIFMAFQYPVeipgvsnqfflqTALNAVRSYRGQ--EPL---DRFDFQDLMEEKIALL---KMPEDL-LTRSV 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 166 PHEFSGGMRQRVMI-AMALLcRPKLLIADEPTTALDVTVQAQIMTLLNELkREFNTAIIMITHDLGVVAGI-CDKVLVMY 243
Cdd:PRK09580 143 NVGFSGGEKKRNDIlQMAVL-EPELCILDESDSGLDIDALKIVADGVNSL-RDGKRSFIIVTHYQRILDYIkPDYVHVLY 220


                 ....*...
gi 556427173 244 AGRTMEYG 251
Cdd:PRK09580 221 QGRIVKSG 228

hmuV

PRK13547

heme ABC transporter ATP-binding protein;

39-262

9.60e-13

heme ABC transporter ATP-binding protein;

Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 67.54 E-value: 9.60e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  39 VNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLL----AANGV-IGGSAKFNGREILNLPEHELNKLRA-----EQISM 108
Cdd:PRK13547  17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLtgggAPRGArVTGDVTLNGEPLAAIDAPRLARLRAvlpqaAQPAF 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 109 IFQ-DPMTSLNPYMrvgeqlmevlmlHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPHEFSGGMRQRVMIAMAL---- 183
Cdd:PRK13547  97 AFSaREIVLLGRYP------------HARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLaqlw 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 184 -----LCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFy 258
Cdd:PRK13547 165 pphdaAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADVL- 243


                 ....
gi 556427173 259 QPAH 262
Cdd:PRK13547 244 TPAH 247

tagH

PRK13545

teichoic acids export protein ATP-binding subunit; Provisional

22-256

1.11e-12

teichoic acids export protein ATP-binding subunit; Provisional

Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 68.76 E-value: 1.11e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  22 VKDLrvTFKTPDGDV-TAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELNK 100
Cdd:PRK13545  24 LKDL--FFRSKDGEYhYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNK---GTVDIKGSAALIAISSGLNG 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 101 lraeQISmifqdpmtslnpymrvGEQLMEVLMLHKGLGKAEAFEESVKMLDavkMPEARKRMRMFPHEFSGGMRQRVMIA 180
Cdd:PRK13545  99 ----QLT----------------GIENIELKGLMMGLTKEKIKEIIPEIIE---FADIGKFIYQPVKTYSSGMKSRLGFA 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556427173 181 MALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:PRK13545 156 ISVHINPDILVIDEALSVGDQTFTKKCLDKMNEFKEQGKT-IFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEV 230

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

26-261

2.34e-12

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 68.05 E-value: 2.34e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173    26 RVTFKT------PDGDVTaVNDLNFNLRAGETLGIVGESGSGKSQTAfalMGLLAANGVIGGSAKFNGreiLNLPEHELN 99
Cdd:TIGR00957 1284 RVEFRNyclryrEDLDLV-LRHINVTIHGGEKVGIVGRTGAGKSSLT---LGLFRINESAEGEIIIDG---LNIAKIGLH 1356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   100 KLRAeQISMIFQDPM-------TSLNPYMRVGEQlmEVLMLHKgLGKAEAFEESVKMLDAVKMPEARKRMrmfphefSGG 172
Cdd:TIGR00957 1357 DLRF-KITIIPQDPVlfsgslrMNLDPFSQYSDE--EVWWALE-LAHLKTFVSALPDKLDHECAEGGENL-------SVG 1425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   173 MRQRVMIAMALLCRPKLLIADEPTTALDVT----VQAQIMTllnelkrEFNTAIIM-ITHDLGVVAGICdKVLVMYAGRT 247
Cdd:TIGR00957 1426 QRQLVCLARALLRKTKILVLDEATAAVDLEtdnlIQSTIRT-------QFEDCTVLtIAHRLNTIMDYT-RVIVLDKGEV 1497

                          250       260
                   ....*....|....*....|
gi 556427173   248 MEYG------KARDVFYQPA 261
Cdd:TIGR00957 1498 AEFGapsnllQQRGIFYSMA 1517

rim_protein

TIGR01257

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

22-246

2.65e-12

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 68.12 E-value: 2.65e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173    22 VKDLRVTFKtPDGDvTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlnlpEHELNKL 101
Cdd:TIGR01257  931 VKNLVKIFE-PSGR-PAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTS---GTVLVGGKDI----ETNLDAV 1001

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   102 RaEQISMIFQDPMtsLNPYMRVGEQLMEVLMLhKGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQRVMIAM 181
Cdd:TIGR01257 1002 R-QSLGMCPQHNI--LFHHLTVAEHILFYAQL-KGRSWEEAQLEMEAMLEDTGLHHKRNEE---AQDLSGGMQRKLSVAI 1074

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173   182 ALLCRPKLLIADEPTTALDVTVQAQIMTLLneLKREFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:TIGR01257 1075 AFVGDAKVVVLDEPTSGVDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGR 1137

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

34-246

5.45e-12

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 66.69 E-value: 5.45e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlnlpehelnklraeqismifqDP 113
Cdd:NF033858 277 GDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASE---GEAWLFGQPV---------------------DA 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 mTSLNPYMRVG---------EQL--MEVLMLHkglgkAEAFEesvkmldavkMPEARKRMRM---------------FPH 167
Cdd:NF033858 333 -GDIATRRRVGymsqafslyGELtvRQNLELH-----ARLFH----------LPAAEIAARVaemlerfdladvadaLPD 396

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 168 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGvVAGICDKVLVMYAGR 246
Cdd:NF033858 397 SLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIELSREDGVTIFISTHFMN-EAERCDRISLMHAGR 474

PRK10762

D-ribose transporter ATP binding protein; Provisional

36-245

6.32e-12

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 66.18 E-value: 6.32e-12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  36 VTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlnlpehELNKLRAEQ---ISMIFQD 112
Cdd:PRK10762  17 VKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDA---GSILYLGKEV------TFNGPKSSQeagIGIIHQE 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 113 pmtsLN--PYMRVGEQLMevlmlhkgLGK-----------AEAFEESVKMLDAVKMPEARKRMRmfpHEFSGGMRQRVMI 179
Cdd:PRK10762  88 ----LNliPQLTIAENIF--------LGRefvnrfgridwKKMYAEADKLLARLNLRFSSDKLV---GELSIGEQQMVEI 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556427173 180 AMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAG 245
Cdd:PRK10762 153 AKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRLKEIFEICDDVTVFRDG 217

PLN03232

ABC transporter C family member; Provisional

42-250

6.93e-12

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 66.54 E-value: 6.93e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   42 LNFNLRAGETLGIVGESGSGKSQTAFALMGLLAangVIGGSAKFNGREILNLPEHELNKLraeqISMIFQDPMT------ 115
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVE---LEKGRIMIDDCDVAKFGLTDLRRV----LSIIPQSPVLfsgtvr 1327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  116 -SLNPYMRvgeqlmevlmlHKGLGKAEAFEESvKMLDAVKMPEARKRMRMFP--HEFSGGMRQRVMIAMALLCRPKLLIA 192
Cdd:PLN03232 1328 fNIDPFSE-----------HNDADLWEALERA-HIKDVIDRNPFGLDAEVSEggENFSVGQRQLLSLARALLRRSKILVL 1395

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173  193 DEPTTALDVTVQAQIMTLLNElkrEFNT-AIIMITHDLGVVAGiCDKVLVMYAGRTMEY 250
Cdd:PLN03232 1396 DEATASVDVRTDSLIQRTIRE---EFKScTMLVIAHRLNTIID-CDKILVLSSGQVLEY 1450

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

36-246

1.19e-11

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 65.32 E-value: 1.19e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  36 VTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANG---VIGGSA-KF-NGREILNlpehelnklraEQISMIF 110
Cdd:PRK11288  17 VKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAgsiLIDGQEmRFaSTTAALA-----------AGVAIIY 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 111 QDpmTSLNPYMRVGEQLMEVLMLHKG--LGKAEAFEESVKMLDAVKM---PEARKRmrmfphEFSGGMRQRVMIAMALLc 185
Cdd:PRK11288  86 QE--LHLVPEMTVAENLYLGQLPHKGgiVNRRLLNYEAREQLEHLGVdidPDTPLK------YLSIGQRQMVEIAKALA- 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556427173 186 RPKLLIA-DEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PRK11288 157 RNARVIAfDEPTSSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGR 217

PTZ00265

multidrug resistance protein (mdr1); Provisional

20-232

1.42e-11

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 65.82 E-value: 1.42e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   20 LDVKDLRVTFKTPDgDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGLL--AANGVIGGSAKFNGREIlNLpehe 97
Cdd:PTZ00265  383 IQFKNVRFHYDTRK-DVEIYKDLNFTLTEGKTYAFVGESGCGKS-TILKLIERLydPTEGDIIINDSHNLKDI-NL---- 455

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   98 lnKLRAEQISMIFQDPMT--------------SLNPYMRVGEQLME-VLMLHKGLGK--------AEAFEESVKMLDAVK 154
Cdd:PTZ00265  456 --KWWRSKIGVVSQDPLLfsnsiknnikyslySLKDLEALSNYYNEdGNDSQENKNKrnscrakcAGDLNDMSNTTDSNE 533

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  155 MPEARKRM-------------RMFPHEF-------------------SGGMRQRVMIAMALLCRPKLLIADEPTTALDVT 202
Cdd:PTZ00265  534 LIEMRKNYqtikdsevvdvskKVLIHDFvsalpdkyetlvgsnasklSGGQKQRISIARAIIRNPKILILDEATSSLDNK 613

                         250       260       270
                  ....*....|....*....|....*....|
gi 556427173  203 VQAQIMTLLNELKREFNTAIIMITHDLGVV 232
Cdd:PTZ00265  614 SEYLVQKTINNLKGNENRITIIIAHRLSTI 643

MK0520

COG2401

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...

37-242

1.52e-11

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];

Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 63.05 E-value: 1.52e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  37 TAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAangviggsakfngREILNLPEHELNKLRAEQISmifqdpmts 116
Cdd:COG2401   44 YVLRDLNLEIEPGEIVLIVGASGSGKS----TLLRLLA-------------GALKGTPVAGCVDVPDNQFG--------- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 117 lnpymrvgeqlmEVLMLHKGLGKAEAFEESVKMLDAVKMPEA---RKRmrmfPHEFSGGMRQRVMIAMALLCRPKLLIAD 193
Cdd:COG2401   98 ------------REASLIDAIGRKGDFKDAVELLNAVGLSDAvlwLRR----FKELSTGQKFRFRLALLLAERPKLLVID 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 556427173 194 EPTTALDVTVqAQIMTL-LNELKREFNTAIIMITHDLGVVAGICDKVLVM 242
Cdd:COG2401  162 EFCSHLDRQT-AKRVARnLQKLARRAGITLVVATHHYDVIDDLQPDLLIF 210

3a01203

TIGR00954

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...

31-227

1.57e-11

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 65.16 E-value: 1.57e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   31 TPDGDVTaVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngviggsakFNGReilnlpeheLNKLRAEQISMIF 110
Cdd:TIGR00954 461 TPNGDVL-IESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPV---------YGGR---------LTKPAKGKLFYVP 521

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  111 QdpmtslNPYMRVG---EQL---MEVL-MLHKGLGKAEAfeesVKMLDAVKMPEARKR------MRMFPHEFSGGMRQRV 177
Cdd:TIGR00954 522 Q------RPYMTLGtlrDQIiypDSSEdMKRRGLSDKDL----EQILDNVQLTHILEReggwsaVQDWMDVLSGGEKQRI 591

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 556427173  178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLnelkREFNTAIIMITH 227
Cdd:TIGR00954 592 AMARLFYHKPQFAILDECTSAVSVDVEGYMYRLC----REFGITLFSVSH 637

PTZ00265

multidrug resistance protein (mdr1); Provisional

20-241

3.10e-11

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 64.67 E-value: 3.10e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   20 LDVKDLRVTFKTPDgDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMG---------LLAANGVIGGSAKF----- 85
Cdd:PTZ00265 1166 IEIMDVNFRYISRP-NVPIYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRfydlkndhhIVFKNEHTNDMTNEqdyqg 1244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   86 ------------------------------NGREIL----NLPEHELNKLRaEQISMIFQDPMTsLNpyMRVGEQLMevl 131
Cdd:PTZ00265 1245 deeqnvgmknvnefsltkeggsgedstvfkNSGKILldgvDICDYNLKDLR-NLFSIVSQEPML-FN--MSIYENIK--- 1317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  132 mlhkgLGKAEAFEESVKMldAVKMPEARKRMRMFPHEF-----------SGGMRQRVMIAMALLCRPKLLIADEPTTALD 200
Cdd:PTZ00265 1318 -----FGKEDATREDVKR--ACKFAAIDEFIESLPNKYdtnvgpygkslSGGQKQRIAIARALLREPKILLLDEATSSLD 1390

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 556427173  201 VTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGiCDKVLV 241
Cdd:PTZ00265 1391 SNSEKLIEKTIVDIKDKADKTIITIAHRIASIKR-SDKIVV 1430

ABCC_MRP_domain1

cd03250

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...

20-246

4.97e-11

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 61.33 E-value: 4.97e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFKTPDGDVTAV-NDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAangVIGGSAKFNGRE--------I 90
Cdd:cd03250    1 ISVEDASFTWDSGEQETSFTlKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELE---KLSGSVSVPGSIayvsqepwI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  91 LNlpehelNKLRaEQIsmIFQDPMtslNPymrvgEQLMEVLmlhkglgKAEAFEESVKMLDAVKMPEArkrmrmfpHE-- 168
Cdd:cd03250   78 QN------GTIR-ENI--LFGKPF---DE-----ERYEKVI-------KACALEPDLEILPDGDLTEI--------GEkg 125

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 169 --FSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMT--LLNELKRefNTAIIMITHDLGVVAgICDKVLVMYA 244
Cdd:cd03250  126 inLSGGQKQRISLARAVYSDADIYLLDDPLSAVDAHVGRHIFEncILGLLLN--NKTRILVTHQLQLLP-HADQIVVLDN 202


                 ..
gi 556427173 245 GR 246
Cdd:cd03250  203 GR 204

PLN03130

ABC transporter C family member; Provisional

42-251

6.60e-11

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 63.60 E-value: 6.60e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   42 LNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELNKLraeqISMIFQDPMT------ 115
Cdd:PLN03130 1258 LSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELER---GRILIDGCDISKFGLMDLRKV----LGIIPQAPVLfsgtvr 1330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  116 -SLNPYmrvGEqlmevlmlHKGLGKAEAFEESvKMLDAVkmpeaRKRMRMFPHE-------FSGGMRQRVMIAMALLCRP 187
Cdd:PLN03130 1331 fNLDPF---NE--------HNDADLWESLERA-HLKDVI-----RRNSLGLDAEvseagenFSVGQRQLLSLARALLRRS 1393

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173  188 KLLIADEPTTALDVTVQAQIMTLLNElkrEFNT-AIIMITHDLGVVAGiCDKVLVMYAGRTMEYG 251
Cdd:PLN03130 1394 KILVLDEATAAVDVRTDALIQKTIRE---EFKScTMLIIAHRLNTIID-CDRILVLDAGRVVEFD 1454

ccmA

TIGR01189

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...

42-232

2.44e-10

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]

Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 59.29 E-value: 2.44e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   42 LNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREIlnlpeHELNKLRAEQISMIFQDPmtSLNPYM 121
Cdd:TIGR01189  19 LSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRP---DSGEVRWNGTPL-----AEQRDEPHENILYLGHLP--GLKPEL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  122 RVGEQLMEVLMLHKGLGKA--EAFEEsVKMLDAVKMPearkrmrmfPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTAL 199
Cdd:TIGR01189  89 SALENLHFWAAIHGGAQRTieDALAA-VGLTGFEDLP---------AAQLSAGQQRRLALARLWLSRRPLWILDEPTTAL 158

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 556427173  200 DVTVQAQIMTLLNE-LKRefNTAIIMITH-DLGVV 232
Cdd:TIGR01189 159 DKAGVALLAGLLRAhLAR--GGIVLLTTHqDLGLV 191

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

43-246

2.92e-10

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 61.08 E-value: 2.92e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  43 NFNLRAGETLGIVGESGSGKSQtafaLMGLL-AANGVIGGSAKFNGREI-LNLPEHelnKLRAeQISMIFQD-------P 113
Cdd:PRK11288 273 SFSVRAGEIVGLFGLVGAGRSE----LMKLLyGATRRTAGQVYLDGKPIdIRSPRD---AIRA-GIMLCPEDrkaegiiP 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 MTS----LNPYMRvGEQLMEVLMLHKGLGKAEAfEESVKMLdAVKMPEARKRMRmfphEFSGGMRQRVMIAMALLCRPKL 189
Cdd:PRK11288 345 VHSvadnINISAR-RHHLRAGCLINNRWEAENA-DRFIRSL-NIKTPSREQLIM----NLSGGNQQKAILGRWLSEDMKV 417

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 190 LIADEPTTALDVTVQAQIMTLLNELKrEFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PRK11288 418 ILLDEPTRGIDVGAKHEIYNVIYELA-AQGVAVLFVSSDLPEVLGVADRIVVMREGR 473

40850658_otr

NF000106

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

34-262

5.12e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 60.13 E-value: 5.12e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQtafalmGLLAANgVIGGSAkfnGREILNLPEHELNKlRAEQISMIFQDP 113
Cdd:NF000106  24 GEVKAVDGVDLDVREGTVLGVLGP*GAA**R------GALPAH-V*GPDA---GRRPWRF*TWCANR-RALRRTIG*HRP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 MTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMfphEFSGGMRQRVMIAMALLCRPKLLIAD 193
Cdd:NF000106  93 VR*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAA---KYSGGMRRRLDLAASMIGRPAVLYLD 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 194 EPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGRTMEYGK---------ARDVFYQPAH 262
Cdd:NF000106 170 EPTTGLDPRTRNEVWDEVRSMVRDGAT-VLLTTQYMEEAEQLAHELTVIDRGRVIADGKvdelktkvgGRTLQIRPAH 246

PRK10636

putative ABC transporter ATP-binding protein; Provisional

34-228

6.31e-10

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 60.18 E-value: 6.31e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIGGSAKfnGREILNLPEHELNKLRAEQismifqdp 113
Cdd:PRK10636 323 GDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAK--GIKLGYFAQHQLEFLRADE-------- 392

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 mTSLNPYMRVGEQLMEvLMLHKGLGkAEAFEEsvkmlDAVKMPEARkrmrmfpheFSGGMRQRVMIAMALLCRPKLLIAD 193
Cdd:PRK10636 393 -SPLQHLARLAPQELE-QKLRDYLG-GFGFQG-----DKVTEETRR---------FSGGEKARLVLALIVWQRPNLLLLD 455

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 556427173 194 EPTTALDVTV-QAqimtlLNELKREFNTAIIMITHD 228
Cdd:PRK10636 456 EPTNHLDLDMrQA-----LTEALIDFEGALVVVSHD 486

ABC_RNaseL_inhibitor_domain1

cd03236

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

47-260

8.45e-10

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 58.53 E-value: 8.45e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  47 RAGETLGIVGESGSGKSQTAFALMGLLAAN-GVIGGSAK-------FNGREILNLpeheLNKLRAEQISMIFQDPMTSLN 118
Cdd:cd03236   24 REGQVLGLVGPNGIGKSTALKILAGKLKPNlGKFDDPPDwdeildeFRGSELQNY----FTKLLEGDVKVIVKPQYVDLI 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 119 PYMRVGEqlmeVLMLHKGLGKAEAFEESVKMLdavkmpEARKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTA 198
Cdd:cd03236  100 PKAVKGK----VGELLKKKDERGKLDELVDQL------ELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSY 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556427173 199 LDVTVQAQIMTLLNELKREFNtAIIMITHDLGVVAGICDKVLVMYaGRTMEYGkardVFYQP 260
Cdd:cd03236  170 LDIKQRLNAARLIRELAEDDN-YVLVVEHDLAVLDYLSDYIHCLY-GEPGAYG----VVTLP 225

PRK13546

teichoic acids export ABC transporter ATP-binding subunit TagH;

22-256

1.37e-09

teichoic acids export ABC transporter ATP-binding subunit TagH;

Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 57.90 E-value: 1.37e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  22 VKDLRVTFKTpDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAfalmgllaanGVIGGSakfngreilnLPEHELNKL 101
Cdd:PRK13546  24 MKDALIPKHK-NKTFFALDDISLKAYEGDVIGLVGINGSGKSTLS----------NIIGGS----------LSPTVGKVD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 102 RAEQISMIFQDpmTSLNPYMrVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEarkrmrmFPHE----FSGGMRQRV 177
Cdd:PRK13546  83 RNGEVSVIAIS--AGLSGQL-TGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGE-------FIYQpvkkYSSGMRAKL 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKrEFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDV 256
Cdd:PRK13546 153 GFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFK-EQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDV 230

ABC_CcmA_heme_exporter

cd03231

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...

42-232

2.59e-09

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.

Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 56.35 E-value: 2.59e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  42 LNFNLRAGETLGIVGESGSGKSqtafALMGLLAangviGGSAKFNGREILN-LPEHELNKLRAEQISMIFQDP--MTSLN 118
Cdd:cd03231   19 LSFTLAAGEALQVTGPNGSGKT----TLLRILA-----GLSPPLAGRVLLNgGPLDFQRDSIARGLLYLGHAPgiKTTLS 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 119 PymrvgeqlMEVLMLHKGLGKAEAFEESVkmldavkmpeARKRMRMFPH----EFSGGMRQRVMIAMALLCRPKLLIADE 194
Cdd:cd03231   90 V--------LENLRFWHADHSDEQVEEAL----------ARVGLNGFEDrpvaQLSAGQQRRVALARLLLSGRPLWILDE 151

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 556427173 195 PTTALDVTVQAQIMTLLNElKREFNTAIIMITH-DLGVV 232
Cdd:cd03231  152 PTTALDKAGVARFAEAMAG-HCARGGMVVLTTHqDLGLS 189

ABCC_CFTR2

cd03289

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...

20-250

3.55e-09

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 56.79 E-value: 3.55e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLrvTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIggsaKFNGREILNLPEHELN 99
Cdd:cd03289    3 MTVKDL--TAKYTEGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTEGDI----QIDGVSWNSVPLQKWR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 KLRA--EQISMIFQDPM-TSLNPYMRVGEQlmEVLMLHKGLGKAEAFEESVKMLDAVKMPEArkrmrmfpHEFSGGMRQR 176
Cdd:cd03289   77 KAFGviPQKVFIFSGTFrKNLDPYGKWSDE--EIWKVAEEVGLKSVIEQFPGQLDFVLVDGG--------CVLSHGHKQL 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556427173 177 VMIAMALLCRPKLLIADEPTTALD-VTVQaqimTLLNELKREFNT-AIIMITHDLGVVAGiCDKVLVMYAGRTMEY 250
Cdd:cd03289  147 MCLARSVLSKAKILLLDEPSAHLDpITYQ----VIRKTLKQAFADcTVILSEHRIEAMLE-CQRFLVIEENKVRQY 217

PRK10790

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

20-259

4.83e-09

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 57.42 E-value: 4.83e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFKTpdgDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAangVIGGSAKFNGREILNLpEHELn 99
Cdd:PRK10790 341 IDIDNVSFAYRD---DNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYP---LTEGEIRLDGRPLSSL-SHSV- 412

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 kLRaEQISMIFQDPMTslnpymrvgeqLMEVLMLHKGLGKaEAFEESV-KMLDAVKMPEARKRMRMFPH--------EFS 170
Cdd:PRK10790 413 -LR-QGVAMVQQDPVV-----------LADTFLANVTLGR-DISEEQVwQALETVQLAELARSLPDGLYtplgeqgnNLS 478

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 171 GGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAGiCDKVLVMYAGRTMEY 250
Cdd:PRK10790 479 VGQKQLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVRE--HTTLVVIAHRLSTIVE-ADTILVLHRGQAVEQ 555

                        250
                 ....*....|....*
gi 556427173 251 GK------ARDVFYQ 259
Cdd:PRK10790 556 GThqqllaAQGRYWQ 570

ABCC_SUR2

cd03288

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...

42-266

6.78e-09

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 55.69 E-value: 6.78e-09

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  42 LNFNLRAGETLGIVGESGSGKSQTAFALMGLLaanGVIGGSAKFNGREILNLPEHELNklraEQISMIFQDPMT------ 115
Cdd:cd03288   40 VKAYIKPGQKVGICGRTGSGKSSLSLAFFRMV---DIFDGKIVIDGIDISKLPLHTLR----SRLSIILQDPILfsgsir 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 116 -SLNPYMR-VGEQLMEVLMLHKGLGKAEAFEESvkmLDAVkMPEARKrmrmfphEFSGGMRQRVMIAMALLCRPKLLIAD 193
Cdd:cd03288  113 fNLDPECKcTDDRLWEALEIAQLKNMVKSLPGG---LDAV-VTEGGE-------NFSVGQRQLFCLARAFVRKSSILIMD 181

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 194 EPTTALDVT----VQAQIMTLLNElkrefnTAIIMITHDLGVVAGiCDKVLVMYAGRTMEYGKARDVFYQPAHPYSI 266
Cdd:cd03288  182 EATASIDMAteniLQKVVMTAFAD------RTVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENLLAQEDGVFAS 251

rim_protein

TIGR01257

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

38-245

6.89e-09

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 57.33 E-value: 6.89e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173    38 AVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAangVIGGSAKFNGREIL-NLPEHELNKLRAEQISMIfQDPMTs 116
Cdd:TIGR01257 1954 AVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTT---VTSGDATVAGKSILtNISDVHQNMGYCPQFDAI-DDLLT- 2028

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   117 lnpymrvGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMrmfPHEFSGGMRQRVMIAMALLCRPKLLIADEPT 196
Cdd:TIGR01257 2029 -------GREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRL---AGTYSGGNKRKLSTAIALIGCPPLVLLDEPT 2098

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 556427173   197 TALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAG 245
Cdd:TIGR01257 2099 TGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEALCTRLAIMVKG 2146

PRK10636

putative ABC transporter ATP-binding protein; Provisional

49-250

1.66e-08

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 55.95 E-value: 1.66e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  49 GETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLPEHELNKLRAEQISMIFQDPmtslnpymRVGEQLM 128
Cdd:PRK10636  27 GQKVGLVGKNGCGKSTLLALLKNEISADG---GSYTFPGNWQLAWVNQETPALPQPALEYVIDGD--------REYRQLE 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 129 EVLMLHKGLGKAEAFEESVKMLDAVKMPEARKRMRMFPH--------------EFSGGMRQRVMIAMALLCRPKLLIADE 194
Cdd:PRK10636  96 AQLHDANERNDGHAIATIHGKLDAIDAWTIRSRAASLLHglgfsneqlerpvsDFSGGWRMRLNLAQALICRSDLLLLDE 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 556427173 195 PTTALDvtVQAQIMtlLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEY 250
Cdd:PRK10636 176 PTNHLD--LDAVIW--LEKWLKSYQGTLILISHDRDFLDPIVDKIIHIEQQSLFEY 227

PRK10938

putative molybdenum transport ATP-binding protein ModF; Provisional

43-217

2.72e-08

putative molybdenum transport ATP-binding protein ModF; Provisional

Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 55.02 E-value: 2.72e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  43 NFNLRAGETLGIVGESGSGKSQTAFALMGLLAangVIGGSAKFNGREILNLPEHELNKLraeqISMIFQDPMTSLnpyMR 122
Cdd:PRK10938  23 SLTLNAGDSWAFVGANGSGKSALARALAGELP---LLSGERQSQFSHITRLSFEQLQKL----VSDEWQRNNTDM---LS 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 123 VGEQlmevlmlHKGLGKAEAFEESVKMLDAVKMPEARKRM-----RMFPHeFSGGMRQRVMIAMALLCRPKLLIADEPTT 197
Cdd:PRK10938  93 PGED-------DTGRTTAEIIQDEVKDPARCEQLAQQFGItalldRRFKY-LSTGETRKTLLCQALMSEPDLLILDEPFD 164

                        170       180
                 ....*....|....*....|
gi 556427173 198 ALDVTVQAQIMTLLNELKRE 217
Cdd:PRK10938 165 GLDVASRQQLAELLASLHQS 184

CFTR_protein

TIGR01271

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...

20-227

4.96e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]

Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 54.53 E-value: 4.96e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173    20 LDVKDLRVTFkTPDGDvTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGVIggsaKFNGreiLNLPEHELN 99
Cdd:TIGR01271 1218 MDVQGLTAKY-TEAGR-AVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTEGEI----QIDG---VSWNSVTLQ 1288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   100 KLRAE-----QISMIFQDPM-TSLNPYMRVGEQlmEVLMLHKGLGKAEAFEESVKMLDAVKMPEArkrmrmfpHEFSGGM 173
Cdd:TIGR01271 1289 TWRKAfgvipQKVFIFSGTFrKNLDPYEQWSDE--EIWKVAEEVGLKSVIEQFPDKLDFVLVDGG--------YVLSNGH 1358

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 556427173   174 RQRVMIAMALLCRPKLLIADEPTTALD-VTVQaqimTLLNELKREF-NTAIIMITH 227
Cdd:TIGR01271 1359 KQLMCLARSILSKAKILLLDEPSAHLDpVTLQ----IIRKTLKQSFsNCTVILSEH 1410

ABC_RNaseL_inhibitor_domain2

cd03237

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

45-253

8.11e-08

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 52.41 E-value: 8.11e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  45 NLRAGETLGIVGESGSGKsqTAFALMglLAangvigGSAKFNGREIlnlpEHELNKL--RAEQISMIFQdpmtslnpyMR 122
Cdd:cd03237   21 SISESEVIGILGPNGIGK--TTFIKM--LA------GVLKPDEGDI----EIELDTVsyKPQYIKADYE---------GT 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 123 VGEQLMEVLmlhKGLGKAEAFE-ESVKMLDAVKMPEARKRmrmfphEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDV 201
Cdd:cd03237   78 VRDLLSSIT---KDFYTHPYFKtEIAKPLQIEQILDREVP------ELSGGELQRVAIAACLSKDADIYLLDEPSAYLDV 148

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 556427173 202 TVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVmYAGRTMEYGKA 253
Cdd:cd03237  149 EQRLMASKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIV-FEGEPSVNGVA 199

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

49-231

8.76e-08

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 50.83 E-value: 8.76e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173    49 GETLGIVGESGSGKSQTAFALMGLLAANGviGGSAKFNGREILNLPEHELNKlraeqismifqdpmtslnpymrvgeqlm 128
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPG--GGVIYIDGEDILEEVLDQLLL---------------------------- 51

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   129 evlmlhkglgkaeafeesvkmldavkmpearKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIM 208
Cdd:smart00382  52 -------------------------------IIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLL 100

                          170       180
                   ....*....|....*....|....*...
gi 556427173   209 -----TLLNELKREFNTAIIMITHDLGV 231
Cdd:smart00382 101 lleelRLLLLLKSEKNLTVILTTNDEKD 128

PRK11147

ABC transporter ATPase component; Reviewed

168-228

9.86e-08

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 53.42 E-value: 9.86e-08

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556427173 168 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVqaqIMTLLNELKrEFNTAIIMITHD 228
Cdd:PRK11147 156 SLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDIET---IEWLEGFLK-TFQGSIIFISHD 212

ABCG_PDR_domain2

cd03232

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...

17-214

1.28e-07

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 51.09 E-value: 1.28e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  17 NLLLDVKDLRVTFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAAN---GVIGGSAKFNGREIlnl 93
Cdd:cd03232    1 GSVLTWKNLNYTVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKT----TLLDVLAGRktaGVITGEILINGRPL--- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  94 pehELNKLR----AEQismifqdpMTSLNPYMRVGEQLMEVLMLhKGLGkaeafeesvkmldavkmPEARKrmrmfphef 169
Cdd:cd03232   74 ---DKNFQRstgyVEQ--------QDVHSPNLTVREALRFSALL-RGLS-----------------VEQRK--------- 115

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 556427173 170 sggmrqRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNEL 214
Cdd:cd03232  116 ------RLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKKL 154

3a01205

TIGR00956

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

170-253

1.70e-07

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 52.80 E-value: 1.70e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   170 SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFN-TAIIMI------THDLgvvagiCDKVLVM 242
Cdd:TIGR00956  211 SGGERKRVSIAEASLGGAKIQCWDNATRGLDSATALEFIRALKTSANILDtTPLVAIyqcsqdAYEL------FDKVIVL 284

                           90
                   ....*....|.
gi 556427173   243 YAGRTMEYGKA 253
Cdd:TIGR00956  285 YEGYQIYFGPA 295

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

46-254

1.74e-07

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 52.48 E-value: 1.74e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  46 LRAGETLGIVGESGSGKsqTAFALMglLAanGVI---GGSAKFNGReILNLP---EHELNKLRAEQISMIFQDPMTSlnP 119
Cdd:COG1245  363 IREGEVLGIVGPNGIGK--TTFAKI--LA--GVLkpdEGEVDEDLK-ISYKPqyiSPDYDGTVEEFLRSANTDDFGS--S 433

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 120 YMRvgEQLMEVLMLHKglgkaeafeesvkMLDavkmpearKRMRmfphEFSGGMRQRVMIAMALLCRPKLLIADEPTTAL 199
Cdd:COG1245  434 YYK--TEIIKPLGLEK-------------LLD--------KNVK----DLSGGELQRVAIAACLSRDADLYLLDEPSAHL 486

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 200 DVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVmYAGRTMEYGKAR 254
Cdd:COG1245  487 DVEQRLAVAKAIRRFAENRGKTAMVVDHDIYLIDYISDRLMV-FEGEPGVHGHAS 540

livF

PRK11614

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

34-246

4.57e-07

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 50.26 E-value: 4.57e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  34 GDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREILNLpehelnklraeQISMIFQDP 113
Cdd:PRK11614  16 GKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATS---GRIVFDGKDITDW-----------QTAKIMREA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 MTSLNPYMRVGEQLM--EVLMLHKGLGKAEAFEESVKMLDAVkMPEARKRMRMFPHEFSGGMRQRVMIAMALLCRPKLLI 191
Cdd:PRK11614  82 VAIVPEGRRVFSRMTveENLAMGGFFAERDQFQERIKWVYEL-FPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLL 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 192 ADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PRK11614 161 LDEPSLGLAPIIIQQIFDTIEQLREQGMT-IFLVEQNANQALKLADRGYVLENGH 214

PRK13539

cytochrome c biogenesis protein CcmA; Provisional

20-231

5.26e-07

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 49.49 E-value: 5.26e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTfktpDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREIlNLPEHeln 99
Cdd:PRK13539   3 LEGEDLACV----RGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPP---AAGTIKLDGGDI-DDPDV--- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 100 klrAEQISMI-FQDPMtslNPYMRVGEQLmevLMLHKGLGKAEAFEESVkmLDAVKMPEARKRmrmfP-HEFSGGMRQRV 177
Cdd:PRK13539  72 ---AEACHYLgHRNAM---KPALTVAENL---EFWAAFLGGEELDIAAA--LEAVGLAPLAHL----PfGYLSAGQKRRV 136

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 178 MIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNElKREFNTAIIMITH-DLGV 231
Cdd:PRK13539 137 ALARLLVSNRPIWILDEPTAALDAAAVALFAELIRA-HLAQGGIVIAATHiPLGL 190

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

19-255

6.61e-07

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 50.82 E-value: 6.61e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  19 LLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqtafALMGLLAanGVI---GGSAKFNGReilnlPE 95
Cdd:PRK15439  11 LLCARSISKQY----SGVEVLKGIDFTLHAGEVHALLGGNGAGKS----TLMKIIA--GIVppdSGTLEIGGN-----PC 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  96 HELNKLRAEQ--ISMIFQDPMtsLNPYMRVGEQLMevlmlhKGLGKAEAFEESVKMLdavkmpEARKRMRMFPHEFSGGM 173
Cdd:PRK15439  76 ARLTPAKAHQlgIYLVPQEPL--LFPNLSVKENIL------FGLPKRQASMQKMKQL------LAALGCQLDLDSSAGSL 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 174 ----RQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTME 249
Cdd:PRK15439 142 evadRQIVEILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRDGTIAL 220


                 ....*.
gi 556427173 250 YGKARD 255
Cdd:PRK15439 221 SGKTAD 226

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

49-234

7.51e-07

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 50.70 E-value: 7.51e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   49 GETLGIVGESGSGKSqtafALMGLLAanGV---IGGSAKF-------------------NGREILNLPEHELNKL--RAE 104
Cdd:TIGR03719  31 GAKIGVLGLNGAGKS----TLLRIMA--GVdkdFNGEARPqpgikvgylpqepqldptkTVRENVEEGVAEIKDAldRFN 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  105 QISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEesVKMlDAVKMPEARKRMRmfphEFSGGMRQRVMIAMALL 184
Cdd:TIGR03719 105 EISAKYAEPDADFDKLAAEQAELQEIIDAADAWDLDSQLE--IAM-DALRCPPWDADVT----KLSGGERRRVALCRLLL 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 556427173  185 CRPKLLIADEPTTALDvtvqAQIMTLLNELKREFNTAIIMITHD---LGVVAG 234
Cdd:TIGR03719 178 SKPDMLLLDEPTNHLD----AESVAWLERHLQEYPGTVVAVTHDryfLDNVAG 226

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

36-246

7.95e-07

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 50.50 E-value: 7.95e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  36 VTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlnlpEHELNKLRAEQ-ISMIFQDpm 114
Cdd:PRK10982  11 VKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDS---GSILFQGKEI----DFKSSKEALENgISMVHQE-- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 115 tsLNPYMRvgEQLMEVLML----HKGLgkaeaFEESVKMLDAVKMPEARKRMRMFPHE----FSGGMRQRVMIAMALLCR 186
Cdd:PRK10982  82 --LNLVLQ--RSVMDNMWLgrypTKGM-----FVDQDKMYRDTKAIFDELDIDIDPRAkvatLSVSQMQMIEIAKAFSYN 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 187 PKLLIADEPTTALDVTVQAQIMTLLNELKrEFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PRK10982 153 AKIVIMDEPTSSLTEKEVNHLFTIIRKLK-ERGCGIVYISHKMEEIFQLCDEITILRDGQ 211

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

9-254

9.46e-07

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 50.19 E-value: 9.46e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   9 APQAQQQNNLLLDVKDLRVTFKtpdgdvtavndlNFNL-------RAGETLGIVGESGSGKsqTAFALMglLAanGVI-- 79
Cdd:PRK13409 330 PPRDESERETLVEYPDLTKKLG------------DFSLeveggeiYEGEVIGIVGPNGIGK--TTFAKL--LA--GVLkp 391

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  80 -GGSakfngreilnlpehelnklraeqismIFQDPMTSLNP-Y------MRVGEQLMEVlmlhkglgkAEAFEES----- 146
Cdd:PRK13409 392 dEGE--------------------------VDPELKISYKPqYikpdydGTVEDLLRSI---------TDDLGSSyykse 436

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 147 -VKMLDAVKMPEarKRMRmfphEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMI 225
Cdd:PRK13409 437 iIKPLQLERLLD--KNVK----DLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVV 510

                        250       260
                 ....*....|....*....|....*....
gi 556427173 226 THDLGVVAGICDKVLVmYAGRTMEYGKAR 254
Cdd:PRK13409 511 DHDIYMIDYISDRLMV-FEGEPGKHGHAS 538

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

46-243

9.98e-07

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 50.17 E-value: 9.98e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  46 LRAGETLGIVGESGSGKSQTAFALMGLLAAN-GVIGGSA-------KFNGREILNLpeheLNKLRAEQISmifqdpmTSL 117
Cdd:COG1245   96 PKKGKVTGILGPNGIGKSTALKILSGELKPNlGDYDEEPswdevlkRFRGTELQDY----FKKLANGEIK-------VAH 164

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 118 NPymrvgeQLMEVL-MLHKG-----LGKAE---AFEESVKMLDAVKMPEarKRMRmfphEFSGGMRQRVMIAMALLCRPK 188
Cdd:COG1245  165 KP------QYVDLIpKVFKGtvrelLEKVDergKLDELAEKLGLENILD--RDIS----ELSGGELQRVAIAAALLRDAD 232

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 189 LLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMY 243
Cdd:COG1245  233 FYFFDEPSSYLDIYQRLNVARLIRELAEE-GKYVLVVEHDLAILDYLADYVHILY 286

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

46-286

1.21e-06

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 49.81 E-value: 1.21e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  46 LRAGETLGIVGESGSGKSQTAFALMGLLAAN-----------GVIggsAKFNGREILNLPEhEL--NKLRA-------EQ 105
Cdd:PRK13409  96 PKEGKVTGILGPNGIGKTTAVKILSGELIPNlgdyeeepswdEVL---KRFRGTELQNYFK-KLynGEIKVvhkpqyvDL 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 106 ISMIFQDpmtslnpymRVGEQLMEVlmlhkglGKAEAFEESVKMLDAVKMPEarKRMRmfphEFSGGMRQRVMIAMALLC 185
Cdd:PRK13409 172 IPKVFKG---------KVRELLKKV-------DERGKLDEVVERLGLENILD--RDIS----ELSGGELQRVAIAAALLR 229

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 186 RPKLLIADEPTTALDVTVQAQIMTLLNELKRefNTAIIMITHDLGVVAGICDKVLVMYaGRTMEYGkardVFYQPA---- 261
Cdd:PRK13409 230 DADFYFFDEPTSYLDIRQRLNVARLIRELAE--GKYVLVVEHDLAVLDYLADNVHIAY-GEPGAYG----VVSKPKgvrv 302

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 556427173 262 -----------------HPYSIGLLNAVPRLDAEGESLLTIP 286
Cdd:PRK13409 303 gineylkgylpeenmriRPEPIEFEERPPRDESERETLVEYP 344

ABC_Rad50

cd03240

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...

54-228

2.21e-06

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.

Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 47.60 E-value: 2.21e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  54 IVGESGSGKSQT----AFALMGLLAANGVIG-GSAKFNGReilnlpehelNKLRAeQISMIFQDPMTSLNPYMRVGEQLM 128
Cdd:cd03240   27 IVGQNGAGKTTIiealKYALTGELPPNSKGGaHDPKLIRE----------GEVRA-QVKLAFENANGKKYTITRSLAILE 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 129 EVLMLHKGlgkaeafeESVKMLdavkmPEARKRMrmfphefSGGMRQ------RVMIAMALLCRPKLLIADEPTTALDV- 201
Cdd:cd03240   96 NVIFCHQG--------ESNWPL-----LDMRGRC-------SGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEe 155

                        170       180
                 ....*....|....*....|....*..
gi 556427173 202 TVQAQIMTLLNELKREFNTAIIMITHD 228
Cdd:cd03240  156 NIEESLAEIIEERKSQKNFQLIVITHD 182

ABCC_SUR1_N

cd03290

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...

35-229

4.62e-06

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 46.94 E-value: 4.62e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  35 DVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGREILNLPEHELNKLRAEQISMIFQDP- 113
Cdd:cd03290   13 GLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQT---LEGKVHWSNKNESEPSFEATRSRNRYSVAYAAQKPw 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 114 ---------MTSLNPYMRvgeqlmevlMLHKGLGKAEAFEESVKMLDAVKMPEARKRmrmfPHEFSGGMRQRVMIAMALL 184
Cdd:cd03290   90 llnatveenITFGSPFNK---------QRYKAVTDACSLQPDIDLLPFGDQTEIGER----GINLSGGQRQRICVARALY 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 556427173 185 CRPKLLIADEPTTALDV-----TVQAQIMTLLNELKRefntAIIMITHDL 229
Cdd:cd03290  157 QNTNIVFLDDPFSALDIhlsdhLMQEGILKFLQDDKR----TLVLVTHKL 202

ABC_RNaseL_inhibitor

cd03222

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...

136-253

4.94e-06

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 46.41 E-value: 4.94e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 136 GLGKAEAfeesVKMLDAVKMPEA------RKRMRMFPH--EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQI 207
Cdd:cd03222   35 GTGKTTA----VKILAGQLIPNGdndewdGITPVYKPQyiDLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNA 110

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 556427173 208 MTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYaGRTMEYGKA 253
Cdd:cd03222  111 ARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIHVFE-GEPGVYGIA 155

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

10-228

5.41e-06

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 48.01 E-value: 5.41e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   10 PQAQQQNNLLLDVKDLRVTFktpdGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALmgllaangvIGGSAKFNGRE 89
Cdd:TIGR03719 313 PPGPRLGDKVIEAENLTKAF----GDKLLIDDLSFKLPPGGIVGVIGPNGAGKS-TLFRM---------ITGQEQPDSGT 378

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   90 IlnlpehELnklrAEQISMIFQDPM-TSLNPYMRVGEQL---MEVLMLhkglGKAE--------AFeesvkmldAVKMPE 157
Cdd:TIGR03719 379 I------EI----GETVKLAYVDQSrDALDPNKTVWEEIsggLDIIKL----GKREipsrayvgRF--------NFKGSD 436

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556427173  158 ARKRMRmfphEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDV-TVQAqimtlLNELKREFNTAIIMITHD 228
Cdd:TIGR03719 437 QQKKVG----QLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDVeTLRA-----LEEALLNFAGCAVVISHD 499

ABC_UvrA

cd03238

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...

32-231

7.85e-06

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 45.78 E-value: 7.85e-06

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  32 PDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFAlmgllaangviGGSAKFNGREILNLPEHELNKLraeqismIFQ 111
Cdd:cd03238    4 SGANVHNLQNLDVSIPLNVLVVVTGVSGSGKSTLVNE-----------GLYASGKARLISFLPKFSRNKL-------IFI 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 112 DPMTSLNP----YMRVGeQLMEVLmlhkglgkaeafeesvkmldavkmpearkrmrmfphefSGGMRQRVMIAMALLCRP 187
Cdd:cd03238   66 DQLQFLIDvglgYLTLG-QKLSTL--------------------------------------SGGELQRVKLASELFSEP 106

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 556427173 188 K--LLIADEPTTALDvtvQAQIMTLLNELKR---EFNTaIIMITHDLGV 231
Cdd:cd03238  107 PgtLFILDEPSTGLH---QQDINQLLEVIKGlidLGNT-VILIEHNLDV 151

PvdE

COG4615

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...

20-112

1.04e-05

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];

Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 47.10 E-value: 1.04e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  20 LDVKDLRVTFKTPDGDVT-AVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANgviGGSAKFNGREIlnlPEHEL 98
Cdd:COG4615  328 LELRGVTYRYPGEDGDEGfTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPE---SGEILLDGQPV---TADNR 401

                         90
                 ....*....|....
gi 556427173  99 NKLRaEQISMIFQD 112
Cdd:COG4615  402 EAYR-QLFSAVFSD 414

PRK13538

cytochrome c biogenesis heme-transporting ATPase CcmA;

41-234

2.17e-05

cytochrome c biogenesis heme-transporting ATPase CcmA;

Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 44.79 E-value: 2.17e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  41 DLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANGvigGSAKFNGREIlnlpehelNKLRAEqismiFQDPM------ 114
Cdd:PRK13538  19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDA---GEVLWQGEPI--------RRQRDE-----YHQDLlylghq 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 115 ----TSLNPYmrvgEQLMEVLMLHKGLGKAEAFEesvkMLDAVKMpeaRKRMRMFPHEFSGGMRQRVMIAMALLCRPKLL 190
Cdd:PRK13538  83 pgikTELTAL----ENLRFYQRLHGPGDDEALWE----ALAQVGL---AGFEDVPVRQLSAGQQRRVALARLWLTRAPLW 151

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 556427173 191 IADEPTTALDVTVQAQIMTLLNE-LKRefNTAIIMITH-DLGVVAG 234
Cdd:PRK13538 152 ILDEPFTAIDKQGVARLEALLAQhAEQ--GGMVILTTHqDLPVASD 195

ABC_Class2

cd03227

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...

170-233

2.32e-05

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.

Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 43.89 E-value: 2.32e-05

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 170 SGGMRQRVMIAMAL-LCRPK---LLIADEPTTALDVTVQAQIMTLLNELKREFNTAIImITHDLGVVA 233
Cdd:cd03227   79 SGGEKELSALALILaLASLKprpLYILDEIDRGLDPRDGQALAEAILEHLVKGAQVIV-ITHLPELAE 145

ABCC_CFTR1

cd03291

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...

41-251

2.45e-05

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 45.23 E-value: 2.45e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  41 DLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAANgviGGSAKFNGREILnlpehelnklrAEQISMIFqdPMTslnpy 120
Cdd:cd03291   55 NINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPS---EGKIKHSGRISF-----------SSQFSWIM--PGT----- 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 121 mrVGEQLMEVLML----HKGLGKAEAFEEsvkmlDAVKMPEARKR-MRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEP 195
Cdd:cd03291  114 --IKENIIFGVSYdeyrYKSVVKACQLEE-----DITKFPEKDNTvLGEGGITLSGGQRARISLARAVYKDADLYLLDSP 186

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 556427173 196 TTALDVTVQAQIMTLLnELKREFNTAIIMITHDLGVVAgICDKVLVMYAGRTMEYG 251
Cdd:cd03291  187 FGYLDVFTEKEIFESC-VCKLMANKTRILVTSKMEHLK-KADKILILHEGSSYFYG 240

uvra

TIGR00630

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...

170-232

2.56e-05

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 46.16 E-value: 2.56e-05

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556427173  170 SGGMRQRVMIAMALLCR---PKLLIADEPTTAL---DVtvqAQIMTLLNELKREFNTaIIMITHDLGVV 232
Cdd:TIGR00630 831 SGGEAQRIKLAKELSKRstgRTLYILDEPTTGLhfdDI---KKLLEVLQRLVDKGNT-VVVIEHNLDVI 895

PLN03073

ABC transporter F family; Provisional

170-246

4.56e-05

ABC transporter F family; Provisional

Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 45.24 E-value: 4.56e-05

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 170 SGGMRQRVMIAMALLCRPKLLIADEPTTALDV-TVQAQIMTLLnelkrEFNTAIIMITHDLGVVAGICDKVLVMYAGR 246
Cdd:PLN03073 629 SGGQKSRVAFAKITFKKPHILLLDEPSNHLDLdAVEALIQGLV-----LFQGGVLMVSHDEHLISGSVDELWVVSEGK 701

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

28-251

6.91e-05

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 44.94 E-value: 6.91e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173    28 TFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLAAngvIGGSAKFNGrEILNLPEHELNKLRAEQIS 107
Cdd:TIGR00957  643 TFTWARDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDK---VEGHVHMKG-SVAYVPQQAWIQNDSLREN 718

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   108 MIFQDPMTSlNPYMRVGEQ---LMEVLMLHKGlGKAEAFEESVKMldavkmpearkrmrmfphefSGGMRQRVMIAMALL 184
Cdd:TIGR00957  719 ILFGKALNE-KYYQQVLEAcalLPDLEILPSG-DRTEIGEKGVNL--------------------SGGQKQRVSLARAVY 776

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556427173   185 CRPKLLIADEPTTALDVTVQAQI-------MTLLNELKRefntaiIMITHDLGVVAGIcDKVLVMYAGRTMEYG 251
Cdd:TIGR00957  777 SNADIYLFDDPLSAVDAHVGKHIfehvigpEGVLKNKTR------ILVTHGISYLPQV-DVIIVMSGGKISEMG 843

PRK11819

putative ABC transporter ATP-binding protein; Reviewed

170-234

7.40e-05

putative ABC transporter ATP-binding protein; Reviewed

Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 44.34 E-value: 7.40e-05

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556427173 170 SGGMRQRVMIAMALLCRPKLLIADEPTTALDvtvqAQIMTLLNELKREFNTAIIMITHD---LGVVAG 234
Cdd:PRK11819 165 SGGERRRVALCRLLLEKPDMLLLDEPTNHLD----AESVAWLEQFLHDYPGTVVAVTHDryfLDNVAG 228

PLN03130

ABC transporter C family member; Provisional

32-251

8.54e-05

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 44.34 E-value: 8.54e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173   32 PDGDVTAVNDLNFNLRAGETLGIVGESGSGKSQTAFALMGLLA----ANGVIGGSAKFngreilnLPehelnklraeQIS 107
Cdd:PLN03130  626 SKAERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGELPprsdASVVIRGTVAY-------VP----------QVS 688

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  108 MIF----QDPMTSLNPYMRVG-EQLMEVLMLHKGLgkaeafeesvKMLDAVKMPEARKRMRmfphEFSGGMRQRVMIAMA 182
Cdd:PLN03130  689 WIFnatvRDNILFGSPFDPERyERAIDVTALQHDL----------DLLPGGDLTEIGERGV----NISGGQKQRVSMARA 754

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  183 LLCRPKLLIADEPTTALDVTVQAQIMTllNELKREF-NTAIIMITHDLGVVAGIcDKVLVMYAGRTMEYG 251
Cdd:PLN03130  755 VYSNSDVYIFDDPLSALDAHVGRQVFD--KCIKDELrGKTRVLVTNQLHFLSQV-DRIILVHEGMIKEEG 821

PLN03073

ABC transporter F family; Provisional

22-201

1.12e-04

ABC transporter F family; Provisional

Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 44.08 E-value: 1.12e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  22 VKDLRV-TFKTPDGDVTAVNDLNFNLRAGETLGIVGESGSGKSqTAFALMGLLAANGV------------IGGSAKFNGR 88
Cdd:PLN03073 175 IKDIHMeNFSISVGGRDLIVDASVTLAFGRHYGLVGRNGTGKT-TFLRYMAMHAIDGIpkncqilhveqeVVGDDTTALQ 253

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173  89 EILNlPEHELNKLRAEQISMIFQDpmTSLNPYMRVGEQLMEVLMLHKGLGKAEAFEESVKMLDAVKMPEARKR------- 161
Cdd:PLN03073 254 CVLN-TDIERTQLLEEEAQLVAQQ--RELEFETETGKGKGANKDGVDKDAVSQRLEEIYKRLELIDAYTAEARaasilag 330

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 556427173 162 -------MRMFPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDV 201
Cdd:PLN03073 331 lsftpemQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDL 377

PRK11147

ABC transporter ATPase component; Reviewed

170-228

1.72e-04

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 43.40 E-value: 1.72e-04

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 556427173 170 SGGMRQRVMIAmALLCRP-KLLIADEPTTALDVtvqaQIMTLLNELKREFNTAIIMITHD 228
Cdd:PRK11147 442 SGGERNRLLLA-RLFLKPsNLLILDEPTNDLDV----ETLELLEELLDSYQGTVLLVSHD 496

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

170-217

5.60e-04

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 41.65 E-value: 5.60e-04

                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 556427173 170 SGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKRE 217
Cdd:NF033858 138 SGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAE 185

PRK00635

excinuclease ABC subunit A; Provisional

170-240

7.89e-04

excinuclease ABC subunit A; Provisional

Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 41.35 E-value: 7.89e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 556427173  170 SGGMRQRVMIAMALLC---RPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIImITHDLGVVAgICDKVL 240
Cdd:PRK00635  811 SGGEIQRLKLAYELLApskKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGHTVVI-IEHNMHVVK-VADYVL 882

COG1106

ATPase/GTPase, AAA15 family [General function prediction only];

159-229

9.90e-04

ATPase/GTPase, AAA15 family [General function prediction only];

Pssm-ID: 440723 [Multi-domain] Cd Length: 330 Bit Score: 40.41 E-value: 9.90e-04

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556427173 159 RKRMRMFP-HEFSGGMRQRVMIAMAL---LCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDL 229
Cdd:COG1106  192 KGGNVPLPlSEESDGTKRLLALAGALldaLAKGGVLLIDEIEASLHPSLLRKLLKLFLDLANKNNAQLIFTTHST 266

PRK15064

ABC transporter ATP-binding protein; Provisional

172-228

3.73e-03

ABC transporter ATP-binding protein; Provisional

Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 39.10 E-value: 3.73e-03

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 556427173 172 GMRQRVMIAMALLCRPKLLIADEPTTALDVTVqaqIMTLLNELkREFNTAIIMITHD 228
Cdd:PRK15064 159 GWKLRVLLAQALFSNPDILLLDEPTNNLDINT---IRWLEDVL-NERNSTMIIISHD 211

3a01205

TIGR00956

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

174-214

4.67e-03

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 38.94 E-value: 4.67e-03

                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 556427173   174 RQRVMIAMALLCRPKLLI-ADEPTTALDVTVQAQIMTLLNEL 214
Cdd:TIGR00956  907 RKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLMRKL 948

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01