|
Name |
Accession |
Description |
Interval |
E-value |
| GlpR |
COG1349 |
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ... |
1-233 |
1.09e-84 |
|
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];
Pssm-ID: 440960 [Multi-domain] Cd Length: 254 Bit Score: 252.75 E-value: 1.09e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 1 MHKTARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAIALNLSAMNR--QGRNTLLPETKQ 78
Cdd:COG1349 1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPpfAERETLNAEEKR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 79 RLGKQVAQQVPAGSTLFLDAGSTVMAVASFLRG--PLTVITTSLDIAQHFSDREDVELILLGGKWDHQQRLFAGSATLSL 156
Cdd:COG1349 81 AIARAAASLIEDGDTIFLDAGTTTLALARALPDrrNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEA 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556475819 157 LSRYRADIAILGACAIHAELGLSAGKEADAEVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLDRPWPE 233
Cdd:COG1349 161 LRRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPP 237
|
|
| DeoRC |
pfam00455 |
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ... |
74-229 |
3.44e-51 |
|
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 395365 Cd Length: 160 Bit Score: 164.22 E-value: 3.44e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 74 PETKQRLGKQVAQQVPAGSTLFLDAGSTVMAVASFL--RGPLTVITTSLDIAQHFSDREDVELILLGGKWDHQQRLFAGS 151
Cdd:pfam00455 3 AEEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALpdRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFVGP 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556475819 152 ATLSLLSRYRADIAILGACAIHAELGLSAGKEADAEVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLDR 229
Cdd:pfam00455 83 LAEEFLRQFNVDKAFIGANGIDLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITDK 160
|
|
| PRK10906 |
PRK10906 |
DeoR/GlpR family transcriptional regulator; |
1-242 |
1.99e-39 |
|
DeoR/GlpR family transcriptional regulator;
Pssm-ID: 182827 [Multi-domain] Cd Length: 252 Bit Score: 136.91 E-value: 1.99e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 1 MHKTARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAiALNLSAMNR--QGRNTLLPETKQ 78
Cdd:PRK10906 1 MKQTQRHDAIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNKILRHHGGA-ALPSSSVNTpwHDRKATQTEEKE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 79 RLGKQVAQQVPAGSTLFLDAGSTVMAVASFLRG--PLTVITTSLDIAQHFSDREDVELILLGGKWDHQQRLFAGSATLSL 156
Cdd:PRK10906 80 RIARKVASQIPNGATLFIDIGTTPEAVAHALLNhsNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATLDF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 157 LSRYRADIAILGACAIHAELGLSAGKEADAEVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLDRPWPelgd 236
Cdd:PRK10906 160 ISQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDQLPP---- 235
|
....*.
gi 556475819 237 PGALQV 242
Cdd:PRK10906 236 ASVMQV 241
|
|
| TranRegGlpR_Halo |
NF041397 |
HTH-type transcriptional regulator GlpR; |
5-233 |
2.88e-36 |
|
HTH-type transcriptional regulator GlpR;
Pssm-ID: 469288 [Multi-domain] Cd Length: 253 Bit Score: 128.49 E-value: 2.88e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 5 ARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAIALNLSAMNRQGRNTLLP--ETKQRLGK 82
Cdd:NF041397 5 ERKRKIVELVTERDGCSVEELADELDVSKATIRRDLRDLEDRGLIERSHGGAVPVTSVGRERSYGQREVQnlEAKRAIAE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 83 QVAQQVPAGSTLFLDAGSTVMAVASFL--RGPLTVITTSLDIAQHFSDReDVELILLGGKWDHQQRLFAGSATLSLLSRY 160
Cdd:NF041397 85 RAVEEIHDGQVVFFDAGTTTMEVAKRVptDGSFLAVTNSPLLALELAER-DGEVKLTGGTLRPRTRALVGPTAESFMERT 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556475819 161 RADIAILGACAIHAELGLSAGKEADAEVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLDRPWPE 233
Cdd:NF041397 164 NFDLLFLGTNGIDPDGGLTTPNEDEARMKELMVENAKRVVLVADGSKFGERSFVRFADLDDVDLFVTDGALPE 236
|
|
| AgaR |
NF040755 |
transcriptional repressor AgaR; |
6-233 |
4.19e-32 |
|
transcriptional repressor AgaR;
Pssm-ID: 468715 [Multi-domain] Cd Length: 256 Bit Score: 117.76 E-value: 4.19e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 6 RQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAI-------ALNLSAMNRQGRNTLLpetKQ 78
Cdd:NF040755 7 RREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALindgfipGAEPSVEDKSRLNTAV---KR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 79 RLGKQVAQQVPAGSTLFLDAGSTVMAVASFLRG--PLTVITTSLDIAQHFSDREDVELILLGGKWDHQQRLFAGSATLSL 156
Cdd:NF040755 84 LIAAAAAELIKPGDRVILDSGTTTYEIARHLKQhqDVVVMTNGLNVANELLEAEGVEVLMTGGHLRRQSLSFYGDQAEQS 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556475819 157 LSRYRADIAILGACAIHAELGLSAGKEADAEVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLDRPWPE 233
Cdd:NF040755 164 LQNYHFDKLFLGVDGFDLERGITTHNEDEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLITDSGIPE 240
|
|
| HTH_DEOR |
smart00420 |
helix_turn_helix, Deoxyribose operon repressor; |
6-57 |
1.42e-12 |
|
helix_turn_helix, Deoxyribose operon repressor;
Pssm-ID: 197714 [Multi-domain] Cd Length: 53 Bit Score: 60.70 E-value: 1.42e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 556475819 6 RQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAI 57
Cdd:smart00420 1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAV 52
|
|
| cas_HTH |
TIGR01884 |
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are ... |
10-48 |
2.90e-04 |
|
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. [Regulatory functions, DNA interactions, , ]
Pssm-ID: 273852 [Multi-domain] Cd Length: 203 Bit Score: 40.80 E-value: 2.90e-04
10 20 30
....*....|....*....|....*....|....*....
gi 556475819 10 VLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGL 48
Cdd:TIGR01884 148 ILEVLKATGEKSVKNIAKKLGKSLSTISRHLAELEKKGL 186
|
|
| WHTH_GntR |
cd07377 |
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ... |
21-54 |
1.16e-03 |
|
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.
Pssm-ID: 153418 [Multi-domain] Cd Length: 66 Bit Score: 36.27 E-value: 1.16e-03
10 20 30
....*....|....*....|....*....|....
gi 556475819 21 SITELAEKLQVSADTIRRDLTDLENQGLAQKNHG 54
Cdd:cd07377 27 SERELAEELGVSRTTVREALRELEAEGLVERRPG 60
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| GlpR |
COG1349 |
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ... |
1-233 |
1.09e-84 |
|
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];
Pssm-ID: 440960 [Multi-domain] Cd Length: 254 Bit Score: 252.75 E-value: 1.09e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 1 MHKTARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAIALNLSAMNR--QGRNTLLPETKQ 78
Cdd:COG1349 1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPpfAERETLNAEEKR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 79 RLGKQVAQQVPAGSTLFLDAGSTVMAVASFLRG--PLTVITTSLDIAQHFSDREDVELILLGGKWDHQQRLFAGSATLSL 156
Cdd:COG1349 81 AIARAAASLIEDGDTIFLDAGTTTLALARALPDrrNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEA 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556475819 157 LSRYRADIAILGACAIHAELGLSAGKEADAEVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLDRPWPE 233
Cdd:COG1349 161 LRRFRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPP 237
|
|
| DeoRC |
pfam00455 |
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ... |
74-229 |
3.44e-51 |
|
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 395365 Cd Length: 160 Bit Score: 164.22 E-value: 3.44e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 74 PETKQRLGKQVAQQVPAGSTLFLDAGSTVMAVASFL--RGPLTVITTSLDIAQHFSDREDVELILLGGKWDHQQRLFAGS 151
Cdd:pfam00455 3 AEEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALpdRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFVGP 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 556475819 152 ATLSLLSRYRADIAILGACAIHAELGLSAGKEADAEVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLDR 229
Cdd:pfam00455 83 LAEEFLRQFNVDKAFIGANGIDLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITDK 160
|
|
| PRK10906 |
PRK10906 |
DeoR/GlpR family transcriptional regulator; |
1-242 |
1.99e-39 |
|
DeoR/GlpR family transcriptional regulator;
Pssm-ID: 182827 [Multi-domain] Cd Length: 252 Bit Score: 136.91 E-value: 1.99e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 1 MHKTARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAiALNLSAMNR--QGRNTLLPETKQ 78
Cdd:PRK10906 1 MKQTQRHDAIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNKILRHHGGA-ALPSSSVNTpwHDRKATQTEEKE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 79 RLGKQVAQQVPAGSTLFLDAGSTVMAVASFLRG--PLTVITTSLDIAQHFSDREDVELILLGGKWDHQQRLFAGSATLSL 156
Cdd:PRK10906 80 RIARKVASQIPNGATLFIDIGTTPEAVAHALLNhsNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATLDF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 157 LSRYRADIAILGACAIHAELGLSAGKEADAEVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLDRPWPelgd 236
Cdd:PRK10906 160 ISQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDQLPP---- 235
|
....*.
gi 556475819 237 PGALQV 242
Cdd:PRK10906 236 ASVMQV 241
|
|
| TranRegGlpR_Halo |
NF041397 |
HTH-type transcriptional regulator GlpR; |
5-233 |
2.88e-36 |
|
HTH-type transcriptional regulator GlpR;
Pssm-ID: 469288 [Multi-domain] Cd Length: 253 Bit Score: 128.49 E-value: 2.88e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 5 ARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAIALNLSAMNRQGRNTLLP--ETKQRLGK 82
Cdd:NF041397 5 ERKRKIVELVTERDGCSVEELADELDVSKATIRRDLRDLEDRGLIERSHGGAVPVTSVGRERSYGQREVQnlEAKRAIAE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 83 QVAQQVPAGSTLFLDAGSTVMAVASFL--RGPLTVITTSLDIAQHFSDReDVELILLGGKWDHQQRLFAGSATLSLLSRY 160
Cdd:NF041397 85 RAVEEIHDGQVVFFDAGTTTMEVAKRVptDGSFLAVTNSPLLALELAER-DGEVKLTGGTLRPRTRALVGPTAESFMERT 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 556475819 161 RADIAILGACAIHAELGLSAGKEADAEVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLDRPWPE 233
Cdd:NF041397 164 NFDLLFLGTNGIDPDGGLTTPNEDEARMKELMVENAKRVVLVADGSKFGERSFVRFADLDDVDLFVTDGALPE 236
|
|
| AgaR |
NF040755 |
transcriptional repressor AgaR; |
6-233 |
4.19e-32 |
|
transcriptional repressor AgaR;
Pssm-ID: 468715 [Multi-domain] Cd Length: 256 Bit Score: 117.76 E-value: 4.19e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 6 RQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAI-------ALNLSAMNRQGRNTLLpetKQ 78
Cdd:NF040755 7 RREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALindgfipGAEPSVEDKSRLNTAV---KR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 79 RLGKQVAQQVPAGSTLFLDAGSTVMAVASFLRG--PLTVITTSLDIAQHFSDREDVELILLGGKWDHQQRLFAGSATLSL 156
Cdd:NF040755 84 LIAAAAAELIKPGDRVILDSGTTTYEIARHLKQhqDVVVMTNGLNVANELLEAEGVEVLMTGGHLRRQSLSFYGDQAEQS 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556475819 157 LSRYRADIAILGACAIHAELGLSAGKEADAEVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLDRPWPE 233
Cdd:NF040755 164 LQNYHFDKLFLGVDGFDLERGITTHNEDEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLITDSGIPE 240
|
|
| PRK09802 |
PRK09802 |
DeoR family transcriptional regulator; |
6-228 |
6.33e-28 |
|
DeoR family transcriptional regulator;
Pssm-ID: 182086 [Multi-domain] Cd Length: 269 Bit Score: 107.25 E-value: 6.33e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 6 RQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAI-------ALNLSAMNRQGRNTLLpetKQ 78
Cdd:PRK09802 18 RREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALicdsttpSVEPSVEDKSALNTAM---KR 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 79 RLGKQVAQQVPAGSTLFLDAGSTVMAVASFLRG--PLTVITTSLDIAQHFSDREDVELILLGGKWDHQQRLFAGSATLSL 156
Cdd:PRK09802 95 SVAKAAVELIQPGHRVILDSGTTTFEIARLMRKhtDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAEQS 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556475819 157 LSRYRADIAILGACAIHAELGLSAGKEADAEVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLD 228
Cdd:PRK09802 175 LQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVD 246
|
|
| srlR |
PRK10434 |
DNA-binding transcriptional repressor; |
1-228 |
2.00e-25 |
|
DNA-binding transcriptional repressor;
Pssm-ID: 182457 [Multi-domain] Cd Length: 256 Bit Score: 100.53 E-value: 2.00e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 1 MHKTARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAIALNLSAMNRQGRNTLL-PETKQR 79
Cdd:PRK10434 1 MKPRQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLInTHKKEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 80 LGKQVAQQVPAGSTLFLDAGSTVMAVASFL--RGPLTVITTSLDIAQHFSDRE-DVELILLGGKWDHQQRLFAGSATLSL 156
Cdd:PRK10434 81 IAEAAVSLIHDGDSIILDAGSTVLQMVPLLsrFNNITVMTNSLHIVNALSELDnEQTILMPGGTFRKKSASFHGQLAENA 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 556475819 157 LSRYRADIAILGACAIHAELGLSAGKEADAeVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLD 228
Cdd:PRK10434 161 FEHFTFDKLFIGTDGIDLNAGVTTFNEVYT-VSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITD 231
|
|
| PRK10411 |
PRK10411 |
L-fucose operon activator; |
3-230 |
9.99e-18 |
|
L-fucose operon activator;
Pssm-ID: 236684 [Multi-domain] Cd Length: 240 Bit Score: 79.46 E-value: 9.99e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 3 KTARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAIALNlsAMNRQGRNTLLPETKQRLGK 82
Cdd:PRK10411 2 KAARQQAIVDLLLNHTSLTTEALAEQLNVSKETIRRDLNELQTQGKILRNHGRAKYIH--RQNQDSGDPFHIRLKSHYAH 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 83 Q--VAQQ----VPAGSTLFLDAGSTVMAVASFLRG-PLTVITTSLDIAQHFSDREDVELILLGGKWDHQQRLFAGSATLS 155
Cdd:PRK10411 80 KadIAREalawIEEGMVIALDASSTCWYLARQLPDiNIQVFTNSHPICQELGKRERIQLISSGGTLERKYGCYVNPSLIS 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 556475819 156 LLSRYRADIAILGACAIHAELGLSAGKEADAEVKRAMLDASHAHWIVADHLKVNRCEPYLVSGLSNIQQLFLDRP 230
Cdd:PRK10411 160 QLKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDER 234
|
|
| PRK13509 |
PRK13509 |
HTH-type transcriptional regulator UlaR; |
4-156 |
1.97e-13 |
|
HTH-type transcriptional regulator UlaR;
Pssm-ID: 184100 [Multi-domain] Cd Length: 251 Bit Score: 67.72 E-value: 1.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 4 TARQRH--VLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAIALNLSAMNRQGRNTLLPET---KQ 78
Cdd:PRK13509 2 TEAQRHqiLLELLAQLGFVTVEKVIERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNIHQAQNhdeKV 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556475819 79 RLGKQVAQQVPAGSTLFLDAGSTVMAVASFLRG-PLTVITTSLDIAQHFSDREDVELILLGGKWDHQQrlfagSATLSL 156
Cdd:PRK13509 82 RIAKAASQLCNPGESVVINCGSTAFLLGRELCGkPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQ-----SITLSP 155
|
|
| HTH_DEOR |
smart00420 |
helix_turn_helix, Deoxyribose operon repressor; |
6-57 |
1.42e-12 |
|
helix_turn_helix, Deoxyribose operon repressor;
Pssm-ID: 197714 [Multi-domain] Cd Length: 53 Bit Score: 60.70 E-value: 1.42e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 556475819 6 RQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAI 57
Cdd:smart00420 1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAV 52
|
|
| HTH_DeoR |
pfam08220 |
DeoR-like helix-turn-helix domain; |
6-60 |
3.83e-12 |
|
DeoR-like helix-turn-helix domain;
Pssm-ID: 285436 [Multi-domain] Cd Length: 57 Bit Score: 59.58 E-value: 3.83e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 556475819 6 RQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAIALN 60
Cdd:pfam08220 1 RIQQILELLKQQGTLSVEELAELLGVSEMTIRRDLNELEEQGLLTRTHGGAVSNS 55
|
|
| PRK10681 |
PRK10681 |
DNA-binding transcriptional repressor DeoR; Provisional |
24-230 |
1.97e-11 |
|
DNA-binding transcriptional repressor DeoR; Provisional
Pssm-ID: 182644 [Multi-domain] Cd Length: 252 Bit Score: 62.02 E-value: 1.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 24 ELAEKLQVSADTIRRDLTdleNQGLAQKNHGGAIALNLSAMNR---QGRNTLLPETKQRLGKQVAQQVPAGSTLFLDAGS 100
Cdd:PRK10681 26 DAAALLGVSEMTIRRDLN---AHSAPVVLLGGYIVLEPRSASHyllSDQKSRLVEEKRRAAQLAATLVEPNQTLFFDCGT 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475819 101 T----VMAVASFLrgPLTVITTSLDIAQHFSDREDVELILLGGKWDHQQRLFAGSATLSLLSRYRADIAILGACAIHAEL 176
Cdd:PRK10681 103 TtpwiIEAIDNEL--PFTAVCYSLNTFLALQEKPHCRAILCGGEFHASNAIFKPLDFQQTLDNICPDIAFYSAAGVHVSK 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 556475819 177 GLSAGKEADAEVK-RAMLDASHaHWIVADHLKVNRCEPYLVSGLSNIQQLFLDRP 230
Cdd:PRK10681 181 GATCFNLEELPVKhWAMAMAQK-HVLVVDHSKFGKVRPARMGDLTRFDTVVSDRC 234
|
|
| YobV |
COG2378 |
Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains ... |
1-47 |
5.48e-06 |
|
Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains [Transcription];
Pssm-ID: 441945 [Multi-domain] Cd Length: 314 Bit Score: 46.61 E-value: 5.48e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 556475819 1 MHKTARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQG 47
Cdd:COG2378 1 MSRLERLLALLQLLQSRRGVTAAELAERLEVSERTIYRDIDALRELG 47
|
|
| COG2345 |
COG2345 |
Predicted transcriptional regulator, ArsR family [Transcription]; |
4-50 |
8.07e-06 |
|
Predicted transcriptional regulator, ArsR family [Transcription];
Pssm-ID: 441914 [Multi-domain] Cd Length: 217 Bit Score: 45.30 E-value: 8.07e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 556475819 4 TARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQ 50
Cdd:COG2345 12 DPTRRRILELLKRAGPVTAAELAEALGLTPNAVRRHLDALEEEGLVE 58
|
|
| HTH_MARR |
smart00347 |
helix_turn_helix multiple antibiotic resistance protein; |
4-48 |
3.43e-05 |
|
helix_turn_helix multiple antibiotic resistance protein;
Pssm-ID: 197670 [Multi-domain] Cd Length: 101 Bit Score: 41.81 E-value: 3.43e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 556475819 4 TARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGL 48
Cdd:smart00347 9 TPTQFLVLRILYEEGPLSVSELAKRLGVSPSTVTRVLDRLEKKGL 53
|
|
| MarR |
pfam01047 |
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ... |
4-48 |
4.59e-05 |
|
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.
Pssm-ID: 426012 [Multi-domain] Cd Length: 59 Bit Score: 40.22 E-value: 4.59e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 556475819 4 TARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGL 48
Cdd:pfam01047 2 TLTQFHILRILYEHGPLTVSELAEKLGVSKSTVTRVLDRLEKKGL 46
|
|
| Put_DNA-bind_N |
pfam06971 |
Putative DNA-binding protein N-terminus; This family represents the N-terminus (approximately ... |
9-40 |
1.38e-04 |
|
Putative DNA-binding protein N-terminus; This family represents the N-terminus (approximately 50 residues) of a number of putative bacterial DNA-binding proteins.
Pssm-ID: 429222 [Multi-domain] Cd Length: 49 Bit Score: 38.58 E-value: 1.38e-04
10 20 30
....*....|....*....|....*....|....
gi 556475819 9 HVLDILSEQGQASI--TELAEKLQVSADTIRRDL 40
Cdd:pfam06971 15 RYLEELEEEGVERIssTELAEALGVTAAQVRKDL 48
|
|
| cas_HTH |
TIGR01884 |
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are ... |
10-48 |
2.90e-04 |
|
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. [Regulatory functions, DNA interactions, , ]
Pssm-ID: 273852 [Multi-domain] Cd Length: 203 Bit Score: 40.80 E-value: 2.90e-04
10 20 30
....*....|....*....|....*....|....*....
gi 556475819 10 VLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGL 48
Cdd:TIGR01884 148 ILEVLKATGEKSVKNIAKKLGKSLSTISRHLAELEKKGL 186
|
|
| HTH_11 |
pfam08279 |
HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins. |
8-48 |
6.19e-04 |
|
HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.
Pssm-ID: 429896 [Multi-domain] Cd Length: 52 Bit Score: 36.64 E-value: 6.19e-04
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 556475819 8 RHVLDILSE-QGQASITELAEKLQVSADTIRRDLTDLENQGL 48
Cdd:pfam08279 1 LQILQLLLEaRGPISGQELAEKLGVSRRTIRRDIKILEELGV 42
|
|
| HTH_24 |
pfam13412 |
Winged helix-turn-helix DNA-binding; |
7-48 |
6.85e-04 |
|
Winged helix-turn-helix DNA-binding;
Pssm-ID: 404317 [Multi-domain] Cd Length: 45 Bit Score: 36.64 E-value: 6.85e-04
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 556475819 7 QRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGL 48
Cdd:pfam13412 3 DRKILNLLQENPRISQRELAERLGLSPSTVNRRLKRLEEEGV 44
|
|
| MntR |
COG1321 |
Mn-dependent transcriptional regulator MntR, DtxR family [Transcription]; |
10-59 |
7.21e-04 |
|
Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];
Pssm-ID: 440932 [Multi-domain] Cd Length: 135 Bit Score: 38.65 E-value: 7.21e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 556475819 10 VLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGGAIAL 59
Cdd:COG1321 15 IYELSEEGGPVRTSDIAERLGVSPPSVTEMLKKLEEKGLVEYEPYGGITL 64
|
|
| WHTH_GntR |
cd07377 |
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ... |
21-54 |
1.16e-03 |
|
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.
Pssm-ID: 153418 [Multi-domain] Cd Length: 66 Bit Score: 36.27 E-value: 1.16e-03
10 20 30
....*....|....*....|....*....|....
gi 556475819 21 SITELAEKLQVSADTIRRDLTDLENQGLAQKNHG 54
Cdd:cd07377 27 SERELAEELGVSRTTVREALRELEAEGLVERRPG 60
|
|
| HTH_ASNC |
smart00344 |
helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase ... |
8-65 |
1.76e-03 |
|
helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli)
Pssm-ID: 214628 [Multi-domain] Cd Length: 108 Bit Score: 37.11 E-value: 1.76e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 556475819 8 RHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGLAQknhGGAIALNLSAMN 65
Cdd:smart00344 6 RKILEELQKDARISLAELAKKVGLSPSTVHNRVKRLEEEGVIK---GYTAVLNPKKLG 60
|
|
| COG4742 |
COG4742 |
Predicted transcriptional regulator, contains HTH domain [Transcription]; |
10-55 |
2.57e-03 |
|
Predicted transcriptional regulator, contains HTH domain [Transcription];
Pssm-ID: 443776 [Multi-domain] Cd Length: 267 Bit Score: 38.34 E-value: 2.57e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 556475819 10 VLDILSEqGQASITELAEKLQVSADTIRRDLTDLENQGLAQKNHGG 55
Cdd:COG4742 21 ILLLLAE-GPKTRSELAESLDVSRSTILRQLKELEERGLIERDDGE 65
|
|
| hrcA |
TIGR00331 |
heat shock gene repressor HrcA; HrcA represses the class I heat shock operons groE and dnaK; ... |
4-53 |
2.77e-03 |
|
heat shock gene repressor HrcA; HrcA represses the class I heat shock operons groE and dnaK; overproduction prevents induction of these operons by heat shock while deletion allows constitutive expression even at low temperatures. In Bacillus subtilis, hrcA is the first gene of the dnaK operon and so is itself a heat shock gene. [Regulatory functions, DNA interactions]
Pssm-ID: 273017 [Multi-domain] Cd Length: 337 Bit Score: 38.42 E-value: 2.77e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 556475819 4 TARQRHVLDILSEQ--------GQASITELAEkLQVSADTIRRDLTDLENQGLAQKNH 53
Cdd:TIGR00331 1 TERQRKILKAIVEEyiktgqpvGSKTLLEKYN-LGLSSATIRNDMADLEDLGFIEKPH 57
|
|
| MarR |
COG1846 |
DNA-binding transcriptional regulator, MarR family [Transcription]; |
4-48 |
3.01e-03 |
|
DNA-binding transcriptional regulator, MarR family [Transcription];
Pssm-ID: 441451 [Multi-domain] Cd Length: 142 Bit Score: 36.87 E-value: 3.01e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 556475819 4 TARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGL 48
Cdd:COG1846 37 TPAQFRVLAALAEAGGLTQSELAERLGLTKSTVSRLLDRLEEKGL 81
|
|
| PRK05472 |
PRK05472 |
redox-sensing transcriptional repressor Rex; Provisional |
9-40 |
3.05e-03 |
|
redox-sensing transcriptional repressor Rex; Provisional
Pssm-ID: 235486 [Multi-domain] Cd Length: 213 Bit Score: 37.79 E-value: 3.05e-03
10 20 30
....*....|....*....|....*....|....
gi 556475819 9 HVLDILSEQGQ--ASITELAEKLQVSADTIRRDL 40
Cdd:PRK05472 20 RYLKELKEEGVerVSSKELAEALGVDSAQIRKDL 53
|
|
| CasRa_I-A |
cd09655 |
CRISPR/Cas system-associated transcriptional regulator CasRa; CRISPR (Clustered Regularly ... |
3-48 |
3.17e-03 |
|
CRISPR/Cas system-associated transcriptional regulator CasRa; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Predicted transcriptional regulator of CRISPR/Cas system
Pssm-ID: 187786 [Multi-domain] Cd Length: 198 Bit Score: 37.74 E-value: 3.17e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 556475819 3 KTARQRHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLENQGL 48
Cdd:cd09655 137 LSREELKILEVLKAKGEKSVKNIAKKLGKSLSTISRHLRELEKKGL 182
|
|
| HTH_AsnC-type |
pfam13404 |
AsnC-type helix-turn-helix domain; |
8-44 |
3.56e-03 |
|
AsnC-type helix-turn-helix domain;
Pssm-ID: 433180 [Multi-domain] Cd Length: 41 Bit Score: 34.27 E-value: 3.56e-03
10 20 30
....*....|....*....|....*....|....*..
gi 556475819 8 RHVLDILSEQGQASITELAEKLQVSADTIRRDLTDLE 44
Cdd:pfam13404 5 RKILRLLQEDARISFAELAERVGLSESTVLRRIRRLE 41
|
|
| BglG |
COG3711 |
Transcriptional antiterminator [Transcription]; |
10-52 |
5.71e-03 |
|
Transcriptional antiterminator [Transcription];
Pssm-ID: 442925 [Multi-domain] Cd Length: 618 Bit Score: 37.53 E-value: 5.71e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 556475819 10 VLDILSEQGQA-SITELAEKLQVSADTIRRDLTDLeNQGLAQKN 52
Cdd:COG3711 1 ILKILLKNNNVvTAKELAKKLNVSERTIRYDIKKI-NEWLKKNG 43
|
|
| |
