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Conserved domains on  [gi|556475935|ref|WP_023327540|]
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MULTISPECIES: ABC transporter permease [Enterobacter]

Protein Classification

ABC transporter permease( domain architecture ID 11439449)

ABC transporter permease is the transmembrane (TM) subunit in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which generally binds a type 2 PBP; similar to the permease subunit of ABC-type dipeptide/oligopeptide/nickel transport systems

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 17-275 4.99e-85

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 255.81  E-value: 4.99e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  17 WQGVAWQPGLWLAWAVIILAIFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAA 96
Cdd:COG1173    9 WRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  97 VTMGLVVGTGLGVIAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIR 176
Cdd:COG1173   89 VLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLR 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 177 HTDYVEAAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWL 256
Cdd:COG1173  169 EREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTAPWL 248

                        250
                 ....*....|....*....
gi 556475935 257 TTFPGVVVIAVVLATNRIS 275
Cdd:COG1173  249 ALFPGLAIVLTVLAFNLLG 267
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 17-275 4.99e-85

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 255.81  E-value: 4.99e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  17 WQGVAWQPGLWLAWAVIILAIFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAA 96
Cdd:COG1173    9 WRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  97 VTMGLVVGTGLGVIAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIR 176
Cdd:COG1173   89 VLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLR 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 177 HTDYVEAAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWL 256
Cdd:COG1173  169 EREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTAPWL 248

                        250
                 ....*....|....*....
gi 556475935 257 TTFPGVVVIAVVLATNRIS 275
Cdd:COG1173  249 ALFPGLAIVLTVLAFNLLG 267
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 28-272 6.81e-52

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 170.64  E-value: 6.81e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935   28 LAWAVIILAIFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGL 107
Cdd:TIGR02790   3 SALLIIAVLFLLAIFAPWIAPHDPLAQNLPMRLLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGLLI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  108 GVIAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVEAAFGS 187
Cdd:TIGR02790  83 GGLAGYIGGRVDEAIMRVCDVFLSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFVLAARTS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  188 GGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGVVVIAV 267
Cdd:TIGR02790 163 GASHWQIIRRHILPNILSPIIVLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQPLLMIYPGLAILIS 242


                  ....*
gi 556475935  268 VLATN 272
Cdd:TIGR02790 243 VMAFN 247
nikC PRK10417
nickel transporter permease NikC; Provisional
 23-274 6.16e-49

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 163.30  E-value: 6.16e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  23 QPGLWLAWAVIILAIFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLV 102
Cdd:PRK10417   3 RWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 103 VGTGLGVIAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVE 182
Cdd:PRK10417  83 LGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 183 AAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGV 262
Cdd:PRK10417 163 AARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYIWTQPLLMFWPGL 242

                        250
                 ....*....|..
gi 556475935 263 VVIAVVLATNRI 274
Cdd:PRK10417 243 ALFISVMAFNLL 254
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 88-268 1.39e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 59.21  E-value: 1.39e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  88 HSLSAALAAVTMGLVVGTGLGVIAGAFAGRVESFLMRFVD--------VLLSIPSLLLSLTVIILLGFGTVNAAIAVGVA 159
Cdd:cd06261    3 NTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDlllslpslVLGLLLVLLFGVLLGWGILPGLGLPALILALL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 160 SIASFARLARGEVVRIRHTDYVEAAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGtPPPVPEW 239
Cdd:cd06261   83 LIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGG-EAPGPGT 161

                        170       180
                 ....*....|....*....|....*....
gi 556475935 240 GLLIAEGRNYLSTAWWLTTFPGVVVIAVV 268
Cdd:cd06261  162 GLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 104-274 3.91e-09

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 55.00  E-value: 3.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  104 GTGLGVIAGAFAGR-VESFLMRFVDVLL---SIPSLLLSLTVIILLGFG-TVNAAIAVGVASIASFARLARGEVVRIRHT 178
Cdd:pfam00528   1 GIPLGIIAALRRGRrLDRLLRPLIDLLQalpSFVLAILLVVIAILSILGhGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  179 DYVEAAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLgyGTPPPVPEWGLLIAEGRNYlSTAWWLTT 258
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFL--GSWPGLGLLLIEAILGYDY-PEIQGPVL 157

                         170
                  ....*....|....*.
gi 556475935  259 FPGVVVIAVVLATNRI 274
Cdd:pfam00528 158 AAALILLLLNLLVDIL 173
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 17-275 4.99e-85

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 255.81  E-value: 4.99e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  17 WQGVAWQPGLWLAWAVIILAIFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAA 96
Cdd:COG1173    9 WRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  97 VTMGLVVGTGLGVIAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIR 176
Cdd:COG1173   89 VLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLR 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 177 HTDYVEAAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWL 256
Cdd:COG1173  169 EREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTAPWL 248

                        250
                 ....*....|....*....
gi 556475935 257 TTFPGVVVIAVVLATNRIS 275
Cdd:COG1173  249 ALFPGLAIVLTVLAFNLLG 267
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 28-272 6.81e-52

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 170.64  E-value: 6.81e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935   28 LAWAVIILAIFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGL 107
Cdd:TIGR02790   3 SALLIIAVLFLLAIFAPWIAPHDPLAQNLPMRLLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGLLI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  108 GVIAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVEAAFGS 187
Cdd:TIGR02790  83 GGLAGYIGGRVDEAIMRVCDVFLSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFVLAARTS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  188 GGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGVVVIAV 267
Cdd:TIGR02790 163 GASHWQIIRRHILPNILSPIIVLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQPLLMIYPGLAILIS 242


                  ....*
gi 556475935  268 VLATN 272
Cdd:TIGR02790 243 VMAFN 247
nikC PRK10417
nickel transporter permease NikC; Provisional
 23-274 6.16e-49

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 163.30  E-value: 6.16e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  23 QPGLWLAWAVIILAIFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLV 102
Cdd:PRK10417   3 RWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 103 VGTGLGVIAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVE 182
Cdd:PRK10417  83 LGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 183 AAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGV 262
Cdd:PRK10417 163 AARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYIWTQPLLMFWPGL 242

                        250
                 ....*....|..
gi 556475935 263 VVIAVVLATNRI 274
Cdd:PRK10417 243 ALFISVMAFNLL 254
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
31-272 4.94e-47

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 159.21  E-value: 4.94e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  31 AVIILAIFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGVI 110
Cdd:PRK09881  38 VIIVLMLLMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCL 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 111 AGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVEAAFGSGGT 190
Cdd:PRK09881 118 SGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAMLAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGAS 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 191 FLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGVVVIAVVLA 270
Cdd:PRK09881 198 RWHLISWHILRNSLPPLIVQASLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWWYCAFPGAAILLTAVG 277


                 ..
gi 556475935 271 TN 272
Cdd:PRK09881 278 FN 279
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 17-272 1.96e-46

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 157.58  E-value: 1.96e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  17 WQGVAWQPGLWLAWAVIILAIFAAVAPGLLTHYSPiEGIAGAQRL--APQAGHWLGTDQLGRDVYTRIVYGASHSLSAAL 94
Cdd:PRK15082  29 WRRFRRQHVALVAGLFVLLLIVVAIFAPWIAPYDA-ENYFDYDALnaGPSLQHWFGVDSLGRDIFSRILVGARISLAAGF 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  95 AAVTMGLVVGTGLGVIAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVR 174
Cdd:PRK15082 108 FSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAILGSGMANVIIAVAIFSIPAFARLVRGNTLV 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 175 IRHTDYVEAAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAW 254
Cdd:PRK15082 188 LKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAQPPTPEWGAMLNEARADMVIAP 267

                        250
                 ....*....|....*...
gi 556475935 255 WLTTFPGVVVIAVVLATN 272
Cdd:PRK15082 268 HVALFPSLAIFLTVLAFN 285
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
31-272 1.95e-43

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 149.93  E-value: 1.95e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  31 AVIILAIFAAVAPGLLTHYSPIEGIAGAQRLAP---QAGHW---LGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVG 104
Cdd:PRK10913  37 VYVVIMLFIAIFANWIAPHNPAEQFRDALLAPPvwqEGGSWahiLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMG 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 105 TGLGVIAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVEAA 184
Cdd:PRK10913 117 VILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIVNAALALTFVALPHYVRLTRAAVLVEVNRDYVTAS 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 185 FGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGVVV 264
Cdd:PRK10913 197 RVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAI 276


                 ....*...
gi 556475935 265 IAVVLATN 272
Cdd:PRK10913 277 LLTVLAFN 284
SapC COG4171
ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];
25-272 6.22e-40

ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];


Pssm-ID: 443331 [Multi-domain]  Cd Length: 296  Bit Score: 140.72  E-value: 6.22e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  25 GLWLAWAVIILAIFAavapGLLTHYSPIEGIAGAQRLAP------QAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVT 98
Cdd:COG4171   32 GLYGFLFLILLALFG----PLLAPYSPDQQFIGALLLPPswddngDVSFFLGTDDLGRDILSRLLYGARYTFGSALLVVL 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  99 MGLVVGTGLGVIAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHT 178
Cdd:COG4171  108 AAAIIGGIIGILAGMSRGLKSSILNHLLDTLLSIPSLLLAIIIVALLGPGLENAMLAITLALLPQFIHAIYQAVHQELKK 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 179 DYVEAAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTT 258
Cdd:COG4171  188 EYVLAARLDGASNWQLLRYSILPNILEVLVTELTRALSIAILDISALGFLGLGAQLPSPEWGAMLGDSLELIYLAPWTVI 267

                        250
                 ....*....|....
gi 556475935 259 FPGVVVIAVVLATN 272
Cdd:COG4171  268 LPGLAIMFSVLIVN 281
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 62-269 9.78e-38

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 136.05  E-value: 9.78e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  62 APQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGVIAGAFAGRVESFLMRFVDVLLSIPSLLLsltV 141
Cdd:COG4239  116 PPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGRVDLLFQRFIEIWSSMPELYL---L 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 142 IILLGFGTVNAAIAVGVASIASFARLA---RGEVVRIRHTDYVEAAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQA 218
Cdd:COG4239  193 IILSSIFQPSFWLLLGILLLFGWMGLVgvvRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNAMVATLTFLPFILSGA 272

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 556475935 219 ILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLsTAWWLtTFPGVVVIAVVL 269
Cdd:COG4239  273 ITTLTSLDFLGFGLPPGSPSLGELLAQGKNNL-QAPWL-GLSAFVVLALML 321
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 32-274 3.34e-32

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 120.33  E-value: 3.34e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  32 VIILAIFAAVAPgLLTHYSPIEGIAGAQRLAP--QAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGV 109
Cdd:PRK15406  46 LVLIALFVILAP-MLSQFAYDDTDWGMMSSAPdmESGHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGS 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 110 IAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVEAAFGSGG 189
Cdd:PRK15406 125 LSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGV 204

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 190 TFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGVVVIAVVL 269
Cdd:PRK15406 205 STRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLF 284


                 ....*
gi 556475935 270 ATNRI 274
Cdd:PRK15406 285 CFNFI 289
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 62-269 1.46e-24

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 100.83  E-value: 1.46e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  62 APQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGVIAGAFAGRVESFLMRFVDVLLSIPSLLLsltV 141
Cdd:PRK15021 116 PPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPTLFL---I 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 142 IILLGFGTVNAAIAVGVASI---ASFARLARGEVVRIRHTDYVEAAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQA 218
Cdd:PRK15021 193 ILLSSVVQPNFWWLLAITVLfgwMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSS 272

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 556475935 219 ILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWW-LTTFPGVVVIAVVL 269
Cdd:PRK15021 273 ITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLgITAFLSVAILLSLL 324
PRK15111 PRK15111
peptide ABC transporter permease SapC;
10-272 2.26e-18

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 82.83  E-value: 2.26e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  10 ARKRVPGWQGVAWQP---------GLWLAWAVIILAIFAavapGLLTHYSPIEGIAGAQRLAPQAGHW------LGTDQL 74
Cdd:PRK15111   8 SEKRPPGTLRTAWRKfysdalamvGLYGCAGLALLCLFG----GWLAPYGIDQQFLGYQLLPPSWSRYgevsffLGTDDL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  75 GRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGVIAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAI 154
Cdd:PRK15111  84 GRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPSLSHAMF 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 155 AVGVASIASFARLARGEVVRIRHTDYVEAAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPP 234
Cdd:PRK15111 164 AVWLALLPRMVRSIYSAVHDELEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIAALGFLDLGAQL 243

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 556475935 235 PVPEWGLLIAEGRNYLSTAWWLTTFPGVVVIAVVLATN 272
Cdd:PRK15111 244 PSPEWGAMLGDSLELIYVAPWTVMLPGAAIMLSVLLVN 281
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 88-268 1.39e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 59.21  E-value: 1.39e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  88 HSLSAALAAVTMGLVVGTGLGVIAGAFAGRVESFLMRFVD--------VLLSIPSLLLSLTVIILLGFGTVNAAIAVGVA 159
Cdd:cd06261    3 NTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDlllslpslVLGLLLVLLFGVLLGWGILPGLGLPALILALL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 160 SIASFARLARGEVVRIRHTDYVEAAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGtPPPVPEW 239
Cdd:cd06261   83 LIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGG-EAPGPGT 161

                        170       180
                 ....*....|....*....|....*....
gi 556475935 240 GLLIAEGRNYLSTAWWLTTFPGVVVIAVV 268
Cdd:cd06261  162 GLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 104-274 3.91e-09

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 55.00  E-value: 3.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  104 GTGLGVIAGAFAGR-VESFLMRFVDVLL---SIPSLLLSLTVIILLGFG-TVNAAIAVGVASIASFARLARGEVVRIRHT 178
Cdd:pfam00528   1 GIPLGIIAALRRGRrLDRLLRPLIDLLQalpSFVLAILLVVIAILSILGhGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  179 DYVEAAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLgyGTPPPVPEWGLLIAEGRNYlSTAWWLTT 258
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFL--GSWPGLGLLLIEAILGYDY-PEIQGPVL 157

                         170
                  ....*....|....*.
gi 556475935  259 FPGVVVIAVVLATNRI 274
Cdd:pfam00528 158 AAALILLLLNLLVDIL 173
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 73-219 1.62e-08

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 54.69  E-value: 1.62e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  73 QLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGVIAGAFAGRVESFLMRFVDVLLSIPSLLLSLTVIILL------- 145
Cdd:COG0601   82 VYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLfavklgw 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935 146 ----GFGTVNA------------AIAVGVASIASFARLARGEVVRIRHTDYVEAAFGSGGTFLAVLWRHILPNALTAVLA 209
Cdd:COG0601  162 lpvsGRVSPWEdfldalrhlilpALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVT 241

                        170
                 ....*....|
gi 556475935 210 FATLQFGQAI 219
Cdd:COG0601  242 VLGLQLGGLL 251
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 26-231 2.00e-03

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 38.68  E-value: 2.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935   26 LWLAWAVIILAIFAAVApGLLTHYSPIEGIAGAQRLAPQAGHWLGTDqlgRDVYTRIVYGASHSLSAALAAVTMGLVVGT 105
Cdd:TIGR01097   4 LIRIWLLALLVALYVWA-FALLGFDLARLLAGPGQMADLLGRMFPPD---WSYLPRILKALLETLAMAILGTVLAAVLAV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556475935  106 GLGVIA--GAFAGRVESFLMRFV-DVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLArGEVVRIRHTDYVE 182
Cdd:TIGR01097  80 PLALLAarNITPSPWLYGLARLLlNFLRAIPELVWALIFVAAVGLGPFAGVLALAFHTVGFLGKLF-AEAIEEVDPGPVE 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 556475935  183 AAFGSGGTFLAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYG 231
Cdd:TIGR01097 159 ALRATGASKLQVIRYGVLPQVLPQFLSYTLYRFEINVRAAAVLGLVGAG 207
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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