NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|556504892|ref|WP_023350900|]
View 

MULTISPECIES: ABC transporter permease [Staphylococcus]

Protein Classification

ABC transporter permease( domain architecture ID 10003065)

ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of substrates including gylcine betaine, choline, and carnitine

Gene Ontology:  GO:0140359|GO:0042626|GO:0055085|GO:0016020
PubMed:  25750732|24638992|31571164|27273632|26517919|18535149|17723295
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 1-208 6.92e-74

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 222.24  E-value: 6.92e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892   1 MIKYLTDNASALFEKTLEHLYISVFALLIAIIIAIPLGILLSKTDKLSKISLTIAGILQTIPTLAILALMIPLFGVGKTP 80
Cdd:COG1174    5 LIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPAP 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  81 AIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGIQLMKDVQLPLALPMILSGIRLSSVYVISWATLASYVGAGG 160
Cdd:COG1174   85 AIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGAGG 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 556504892 161 LGDFIFNGLNLFEPAMIITATILVTLLALIVDFCLSMIEKWLVPKGLR 208
Cdd:COG1174  165 LGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTPRGLR 212
 
Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 1-208 6.92e-74

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 222.24  E-value: 6.92e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892   1 MIKYLTDNASALFEKTLEHLYISVFALLIAIIIAIPLGILLSKTDKLSKISLTIAGILQTIPTLAILALMIPLFGVGKTP 80
Cdd:COG1174    5 LIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPAP 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  81 AIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGIQLMKDVQLPLALPMILSGIRLSSVYVISWATLASYVGAGG 160
Cdd:COG1174   85 AIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGAGG 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 556504892 161 LGDFIFNGLNLFEPAMIITATILVTLLALIVDFCLSMIEKWLVPKGLR 208
Cdd:COG1174  165 LGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTPRGLR 212
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
57-202 1.72e-16

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 75.36  E-value: 1.72e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  57 ILQTIPTLAILALMIPLFGVGKTPAIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGIQLMKDVQLPLALPMIL 136
Cdd:PRK11365 103 MLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIM 182

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892 137 SGIRLSsvYVISWATL--ASYVGA-GGLGDFIFNGLNLFEPAMIITATILVTLLALIVDFCLSMIEK-WL 202
Cdd:PRK11365 183 VGVRFA--LGLMWLTLivAETISAnSGIGYLAMNAREFLQTDVVVVAIILYALLGKLADVSAQLLERlWL 250
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 46-205 2.23e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 65.40  E-value: 2.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892   46 KLSKISLTIAGILQTIPTLAILALMIPL-----FGVGKTPAIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGI 120
Cdd:pfam00528  15 RLDRLLRPLIDLLQALPSFVLAILLVVIailsiLGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRW 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  121 QLMKDVQLPLALPMILSGIRLSSVYVISWATLASYVGAG-GLGDFIFNGLNLFEPAMIITATILVTLLALIVDFCLSMIE 199
Cdd:pfam00528  95 QIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQ 174


                  ....*.
gi 556504892  200 KWLVPK 205
Cdd:pfam00528 175 RLLDPR 180
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 42-191 6.56e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 50.74  E-value: 6.56e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  42 SKTDKLSKISLTIAGILQTIPTLAILALMIPLFGVGKT---------PAIIALFLYVLLPILNNTIIGVQNIDSNVKEAG 112
Cdd:cd06261   28 RKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGwgilpglglPALILALLLIAPFARLIRRAALESIPKDLVEAA 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892 113 RSMGMTGIQLMKDVQLPLALPMILSGIRLSSVYVISWATLASYVGAG---GLGDFIFNGLNLFEPAMIITATILVTLLAL 189
Cdd:cd06261  108 RALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGeapGPGTGLLLIFAILFPGDLGVAAAVALILLL 187


                 ..
gi 556504892 190 IV 191
Cdd:cd06261  188 LS 189
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 47-202 3.24e-06

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 46.38  E-value: 3.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892   47 LSKISLTIAGILQTIPTLAILALMIPLFGVGKTPAIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGIQLMKDV 126
Cdd:TIGR01097  95 LYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYG 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  127 QLPLALPMILSgirlSSVYV----ISWATLASYVGAGGLGDFIFNGLNLFE--PAMIITATILVtlLALIVDFCLSMIEK 200
Cdd:TIGR01097 175 VLPQVLPQFLS----YTLYRfeinVRAAAVLGLVGAGGIGLELDTAIGLFDydEVSAIILVILV--VVVIIDLISARLRR 248


                  ..
gi 556504892  201 WL 202
Cdd:TIGR01097 249 RL 250
 
Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 1-208 6.92e-74

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 222.24  E-value: 6.92e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892   1 MIKYLTDNASALFEKTLEHLYISVFALLIAIIIAIPLGILLSKTDKLSKISLTIAGILQTIPTLAILALMIPLFGVGKTP 80
Cdd:COG1174    5 LIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPAP 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  81 AIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGIQLMKDVQLPLALPMILSGIRLSSVYVISWATLASYVGAGG 160
Cdd:COG1174   85 AIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGAGG 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 556504892 161 LGDFIFNGLNLFEPAMIITATILVTLLALIVDFCLSMIEKWLVPKGLR 208
Cdd:COG1174  165 LGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTPRGLR 212
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 47-204 3.35e-27

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 103.69  E-value: 3.35e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  47 LSKISLTIAGILQTIPTLAILALMIPLFGVGKTPAIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGIQLMKDV 126
Cdd:COG0600   94 LRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKV 173

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 556504892 127 QLPLALPMILSGIRLSSVYVISWATLASYVGAG-GLGDFIFNGLNLFEPAMIITATILVTLLALIVDFCLSMIEKWLVP 204
Cdd:COG0600  174 VLPAALPYIFTGLRIALGLAWIGLVVAELLGASsGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLLRLLERRLLR 252
ProW COG4176
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 42-192 7.00e-22

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443335  Cd Length: 275  Bit Score: 90.16  E-value: 7.00e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  42 SKTDKLSKISLTIAGILQTIPTLAILALMIPLFGVGKTPAIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGIQ 121
Cdd:COG4176  118 ARSDRVSRIVRPVLDFMQTMPAFVYLIPAVMLFGIGKVPGVIATVIFALPPAIRLTNLGIRQVPKELVEAADAFGATPWQ 197

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556504892 122 LMKDVQLPLALPMILSGIRLSSVYVISWATLASYVGAGGLGDFIFNGLNLFEPAMIITATILVTLLALIVD 192
Cdd:COG4176  198 LLFKVQLPLALPTIMAGVNQTIMLALSMVVIASMIGAGGLGQEVLRALQRLDIGLGFEAGLAIVILAIILD 268
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
57-202 1.72e-16

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 75.36  E-value: 1.72e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  57 ILQTIPTLAILALMIPLFGVGKTPAIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGIQLMKDVQLPLALPMIL 136
Cdd:PRK11365 103 MLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIM 182

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892 137 SGIRLSsvYVISWATL--ASYVGA-GGLGDFIFNGLNLFEPAMIITATILVTLLALIVDFCLSMIEK-WL 202
Cdd:PRK11365 183 VGVRFA--LGLMWLTLivAETISAnSGIGYLAMNAREFLQTDVVVVAIILYALLGKLADVSAQLLERlWL 250
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
42-192 3.59e-16

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 75.51  E-value: 3.59e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  42 SKTDKLSKISLTIAGILQTIPTLAILALMIPLFGVGKTPAIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGIQ 121
Cdd:PRK10952 172 ARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTILGINQVPADLIEASRSFGASPRQ 251

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 556504892 122 LMKDVQLPLALPMILSGIRLSSVYVISWATLASYVGAGGLGDFIFNGLNLFEPAMIITATILVTLLALIVD 192
Cdd:PRK10952 252 MLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILD 322
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 46-205 2.23e-13

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 65.40  E-value: 2.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892   46 KLSKISLTIAGILQTIPTLAILALMIPL-----FGVGKTPAIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGI 120
Cdd:pfam00528  15 RLDRLLRPLIDLLQALPSFVLAILLVVIailsiLGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRW 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  121 QLMKDVQLPLALPMILSGIRLSSVYVISWATLASYVGAG-GLGDFIFNGLNLFEPAMIITATILVTLLALIVDFCLSMIE 199
Cdd:pfam00528  95 QIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQ 174


                  ....*.
gi 556504892  200 KWLVPK 205
Cdd:pfam00528 175 RLLDPR 180
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 104-193 2.21e-11

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 60.84  E-value: 2.21e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892 104 IDSNVKEAGRSMGMTGIQLMKDVQLPLALPMILSGIRLSSVYVISWATLASYVGAGGLGDF-IFNGLNLFEPAMIITATI 182
Cdd:COG2011  118 VDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISLIGYSAMAGAVGGGGLGDLaIRYGYQRFDTDVMLVTVV 197

                         90
                 ....*....|.
gi 556504892 183 LVTLLALIVDF 193
Cdd:COG2011  198 ILIVLVQIIQF 208
PRK10160 PRK10160
taurine ABC transporter permease TauC;
50-204 2.25e-10

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 58.64  E-value: 2.25e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  50 ISLTIAGIL-------QTIPTLAILALMIPLFGVGKTPAIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGIQL 122
Cdd:PRK10160 107 LSPTVRGILdplielyRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAAQSLGASRAQV 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892 123 MKDVQLPLALPMILSGIRLSsvYVISWATL--ASYVGAG-GLGdFIFNGLNLFEPAMIITATILV-TLLALIVDFCLSMI 198
Cdd:PRK10160 187 LWFVILPGALPEILTGLRIG--LGVGWSTLvaAELIAATrGLG-FMVQSAGEFLATDVVLAGIAViAIIAFLLELGLRAL 263


                 ....*.
gi 556504892 199 EKWLVP 204
Cdd:PRK10160 264 QRRLTP 269
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 42-191 6.56e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 50.74  E-value: 6.56e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  42 SKTDKLSKISLTIAGILQTIPTLAILALMIPLFGVGKT---------PAIIALFLYVLLPILNNTIIGVQNIDSNVKEAG 112
Cdd:cd06261   28 RKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGwgilpglglPALILALLLIAPFARLIRRAALESIPKDLVEAA 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892 113 RSMGMTGIQLMKDVQLPLALPMILSGIRLSSVYVISWATLASYVGAG---GLGDFIFNGLNLFEPAMIITATILVTLLAL 189
Cdd:cd06261  108 RALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGeapGPGTGLLLIFAILFPGDLGVAAAVALILLL 187


                 ..
gi 556504892 190 IV 191
Cdd:cd06261  188 LS 189
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 47-203 9.35e-07

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 47.77  E-value: 9.35e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  47 LSKISLTIAGILQTIPTLAILALMIPLFGVGKTPAIIALFLY---VLLPILNNTIigvQNIDSNVKEAGRSMGMTGIQLM 123
Cdd:COG3639   88 VRLLARRLLNVLRAIPELVWALIFVAAVGLGPFAGVLALAIHtigFLGKLFAEAI---EEIDPGPVEALRATGASRLQVI 164

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892 124 KDVQLPLALPMILSgirlSSVYV----ISWATLASYVGAGGLGDFIFNGLNLFEPAMIITATILVTLLALIVDFCLSMIE 199
Cdd:COG3639  165 RYGVLPQVLPQFLS----YTLYRfeinIRAATVLGLVGAGGIGLLLNEAIRLFQYDEVAAILLVILVLVLLIDLLSARLR 240


                 ....
gi 556504892 200 KWLV 203
Cdd:COG3639  241 RRLI 244
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 47-202 3.24e-06

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 46.38  E-value: 3.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892   47 LSKISLTIAGILQTIPTLAILALMIPLFGVGKTPAIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTGIQLMKDV 126
Cdd:TIGR01097  95 LYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYG 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  127 QLPLALPMILSgirlSSVYV----ISWATLASYVGAGGLGDFIFNGLNLFE--PAMIITATILVtlLALIVDFCLSMIEK 200
Cdd:TIGR01097 175 VLPQVLPQFLS----YTLYRfeinVRAAAVLGLVGAGGIGLELDTAIGLFDydEVSAIILVILV--VVVIIDLISARLRR 248


                  ..
gi 556504892  201 WL 202
Cdd:TIGR01097 249 RL 250
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
46-194 1.03e-05

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 44.72  E-value: 1.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556504892  46 KLSKISLTIAGILQTIPTLAILALMIPLF------GVGKTPAIIALFLYVLLPILNNTIIGVQNIDSNVKEAGRSMGMTG 119
Cdd:PRK10782  51 KLYRTLSALVNIFRSIPFIILLVWMIPFTrvivgtSIGLQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGATP 130

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 556504892 120 IQLMKDVQLPLALPMILSGIRLSSVYVISWATLASYVGAGGLGDFIFN-GLNLFEPAMIITATILVTLLALIVDFC 194
Cdd:PRK10782 131 MQIVRKVLLPEALPGLVNAATITLITLVGYSAMGGAVGAGGLGQIGYQyGYIGYNATVMNTVLVLLVILVYLIQFA 206
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
82-148 7.55e-03

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 36.68  E-value: 7.55e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 556504892  82 IIALFLYVLLPILNntiiGVQNIDSNVKEAGRSMGMTGIQLMKDVQLPLALPMILSGIRLSSVYVIS 148
Cdd:COG1178  147 VLFNYPYVYLLLRA----ALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLA 209
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH