|
Name |
Accession |
Description |
Interval |
E-value |
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
44-363 |
1.80e-76 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 239.46 E-value: 1.80e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 44 KPVQSWHTYTTRLESPQEVALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQIHSAEAALEQAKSEDK 123
Cdd:COG0845 6 GDVPETVEATGTVEARREVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPPDLQAALAQAQAQLAAAQAQLELAKAELE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 124 RAVRLLERKAISTEQAQARTSTLRQREAQLAALQAQLTSAKLDLEFTSVVSPIDGVISRANITKGNNVLAGQSVLTsIVS 203
Cdd:COG0845 86 RYKALLKKGAVSQQELDQAKAALDQAQAALAAAQAALEQARANLAYTTIRAPFDGVVGERNVEPGQLVSAGTPLFT-IAD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 204 NKAMYAYFDVDERTWNSafndvtAQSRQTVVMQKVGQKEFAYQGYINFIDNQINSATGTLRVRAVFEQDNNQLRAGSFAR 283
Cdd:COG0845 165 LDPLEVEFDVPESDLAR------LKVGQPVTVTLDAGPGKTFEGKVTFIDPAVDPATRTVRVRAELPNPDGLLRPGMFVR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 284 VKLAANEVSEKVIIPERAIGTDLKNRFVLTVGENNVLEYKLIEVGERYGALRAVTAGLNEGDIIAVNGPARVGPGMPISP 363
Cdd:COG0845 239 VRIVLGERENALLVPASAVVRDGGGAYVFVVDADGKVERRPVTLGRRDGDQVEVLSGLKAGDRVVVSGLQRLRDGAKVRV 318
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
51-363 |
4.23e-60 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 197.15 E-value: 4.23e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 51 TYTTRLESPQEVALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQIHSAEAALEQAKSEDKRAVRLLE 130
Cdd:TIGR01730 16 TFPGSLEAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDDDYQLALQAALAQLAAAEAQLELAQRSFERAERLVK 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 131 RKAISTEQAQARTSTLRQREAQLAALQAQLTSAKLDLEFTSVVSPIDGVISRANITKGNNVLAGQSVLTsIVSNKAMYAY 210
Cdd:TIGR01730 96 RNAVSQADLDDAKAAVEAAQADLEAAKASLASAQLNLRYTEIRAPFDGTIGRRLVEVGAYVTAGQTLAT-IVDLDPLEAD 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 211 FDVDERTWNSAFNDVTAQsrqtVVMQKVGQKEFayQGYINFIDNQINSATGTLRVRAVFEQDNNQLRAGSFARVKLAANE 290
Cdd:TIGR01730 175 FSVPERDLPQLRRGQTLT----VELDALPGEEF--KGKLRFIDPRVDSGTGTVRVRATFPNPDGRLLPGMFGRVTISLKV 248
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 567929810 291 VSEKVIIPERAIGTDLKNRFVLTVGENNVLEYKLIEVGERYGALRAVTAGLNEGDIIAVNGPARVGPGMPISP 363
Cdd:TIGR01730 249 RSSAIVVPTQAVIEDLNGKYVYVVKNDGKVSKRPVEVGLRNGGYVEIESGLKAGDQIVTAGVVKLRDGAKVKV 321
|
|
| PRK11556 |
PRK11556 |
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit; |
62-359 |
1.58e-30 |
|
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 183194 [Multi-domain] Cd Length: 415 Bit Score: 121.05 E-value: 1.58e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 62 VALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQIHSAEAALEQAKSEDKRAVRLLERKAISTEQAQA 141
Cdd:PRK11556 88 VTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPRPFKVALAQAQGQLAKDQATLANARRDLARYQQLAKTNLVSRQELDA 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 142 RTSTLRQREAQLAALQAQLTSAKLDLEFTSVVSPIDGVISRANITKGNNVLAGQSvlTSIVSNKAMY---AYFDVDERTW 218
Cdd:PRK11556 168 QQALVSETEGTIKADEASVASAQLQLDYSRITAPISGRVGLKQVDVGNQISSGDT--TGIVVITQTHpidLVFTLPESDI 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 219 NSAfndVTAQ-SRQTVVMQ---KVGQKEFAyQGYINFIDNQINSATGTLRVRAVFEQDNNQLRAGSFARVKLAANEVSEK 294
Cdd:PRK11556 246 ATV---VQAQkAGKPLVVEawdRTNSKKLS-EGTLLSLDNQIDATTGTIKLKARFNNQDDALFPNQFVNARMLVDTLQNA 321
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 567929810 295 VIIPERAIGTDLKNRFVLTVGENNVLEYKLIEVGERYGALRAVTAGLNEGDIIAVNGPARVGPGM 359
Cdd:PRK11556 322 VVIPTAALQMGNEGHFVWVLNDENKVSKHLVTPGIQDSQKVVISAGLSAGDRVVTDGIDRLTEGA 386
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
45-349 |
4.37e-28 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 112.52 E-value: 4.37e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 45 PVQSWHTYTTRLE-SPQEVALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQIHSAEAALEQAKSEDK 123
Cdd:pfam00529 3 PLTKGVEAPGRVVvSGNAKAVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAELD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 124 RAVRLLERKAISTEQAQARTSTLRQREAQLAALQAQLTSAKLDLEFTSVVSPIDGVISRANITKGNNVLAGQ-SVLTSIV 202
Cdd:pfam00529 83 RLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTAGALVAQAQaNLLATVA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 203 SNKAMYAYFDVDERTWNSAFNDVTAQSRQTVVMQKVGQKEFAYQ-----------GYINFIDNQINSATGTLRVRAVFEQ 271
Cdd:pfam00529 163 QLDQIYVQITQSAAENQAEVRSELSGAQLQIAEAEAELKLAKLDlerteirapvdGTVAFLSVTVDGGTVSAGLRLMFVV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 272 DNNQ-LRAGSFARVKLAANEVSEKVIIPERAIGTDLKNRFVLTV-GENNVLEYKLIEVGERYGALRAVTAGLNEGDIIAV 349
Cdd:pfam00529 243 PEDNlLVPGMFVETQLDQVRVGQPVLIPFDAFPQTKTGRFTGVVvGISPDTGPVRVVVDKAQGPYYPLRIGLSAGALVRL 322
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
44-363 |
1.80e-76 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 239.46 E-value: 1.80e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 44 KPVQSWHTYTTRLESPQEVALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQIHSAEAALEQAKSEDK 123
Cdd:COG0845 6 GDVPETVEATGTVEARREVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPPDLQAALAQAQAQLAAAQAQLELAKAELE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 124 RAVRLLERKAISTEQAQARTSTLRQREAQLAALQAQLTSAKLDLEFTSVVSPIDGVISRANITKGNNVLAGQSVLTsIVS 203
Cdd:COG0845 86 RYKALLKKGAVSQQELDQAKAALDQAQAALAAAQAALEQARANLAYTTIRAPFDGVVGERNVEPGQLVSAGTPLFT-IAD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 204 NKAMYAYFDVDERTWNSafndvtAQSRQTVVMQKVGQKEFAYQGYINFIDNQINSATGTLRVRAVFEQDNNQLRAGSFAR 283
Cdd:COG0845 165 LDPLEVEFDVPESDLAR------LKVGQPVTVTLDAGPGKTFEGKVTFIDPAVDPATRTVRVRAELPNPDGLLRPGMFVR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 284 VKLAANEVSEKVIIPERAIGTDLKNRFVLTVGENNVLEYKLIEVGERYGALRAVTAGLNEGDIIAVNGPARVGPGMPISP 363
Cdd:COG0845 239 VRIVLGERENALLVPASAVVRDGGGAYVFVVDADGKVERRPVTLGRRDGDQVEVLSGLKAGDRVVVSGLQRLRDGAKVRV 318
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
51-363 |
4.23e-60 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 197.15 E-value: 4.23e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 51 TYTTRLESPQEVALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQIHSAEAALEQAKSEDKRAVRLLE 130
Cdd:TIGR01730 16 TFPGSLEAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDDDYQLALQAALAQLAAAEAQLELAQRSFERAERLVK 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 131 RKAISTEQAQARTSTLRQREAQLAALQAQLTSAKLDLEFTSVVSPIDGVISRANITKGNNVLAGQSVLTsIVSNKAMYAY 210
Cdd:TIGR01730 96 RNAVSQADLDDAKAAVEAAQADLEAAKASLASAQLNLRYTEIRAPFDGTIGRRLVEVGAYVTAGQTLAT-IVDLDPLEAD 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 211 FDVDERTWNSAFNDVTAQsrqtVVMQKVGQKEFayQGYINFIDNQINSATGTLRVRAVFEQDNNQLRAGSFARVKLAANE 290
Cdd:TIGR01730 175 FSVPERDLPQLRRGQTLT----VELDALPGEEF--KGKLRFIDPRVDSGTGTVRVRATFPNPDGRLLPGMFGRVTISLKV 248
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 567929810 291 VSEKVIIPERAIGTDLKNRFVLTVGENNVLEYKLIEVGERYGALRAVTAGLNEGDIIAVNGPARVGPGMPISP 363
Cdd:TIGR01730 249 RSSAIVVPTQAVIEDLNGKYVYVVKNDGKVSKRPVEVGLRNGGYVEIESGLKAGDQIVTAGVVKLRDGAKVKV 321
|
|
| PRK11556 |
PRK11556 |
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit; |
62-359 |
1.58e-30 |
|
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 183194 [Multi-domain] Cd Length: 415 Bit Score: 121.05 E-value: 1.58e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 62 VALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQIHSAEAALEQAKSEDKRAVRLLERKAISTEQAQA 141
Cdd:PRK11556 88 VTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPRPFKVALAQAQGQLAKDQATLANARRDLARYQQLAKTNLVSRQELDA 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 142 RTSTLRQREAQLAALQAQLTSAKLDLEFTSVVSPIDGVISRANITKGNNVLAGQSvlTSIVSNKAMY---AYFDVDERTW 218
Cdd:PRK11556 168 QQALVSETEGTIKADEASVASAQLQLDYSRITAPISGRVGLKQVDVGNQISSGDT--TGIVVITQTHpidLVFTLPESDI 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 219 NSAfndVTAQ-SRQTVVMQ---KVGQKEFAyQGYINFIDNQINSATGTLRVRAVFEQDNNQLRAGSFARVKLAANEVSEK 294
Cdd:PRK11556 246 ATV---VQAQkAGKPLVVEawdRTNSKKLS-EGTLLSLDNQIDATTGTIKLKARFNNQDDALFPNQFVNARMLVDTLQNA 321
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 567929810 295 VIIPERAIGTDLKNRFVLTVGENNVLEYKLIEVGERYGALRAVTAGLNEGDIIAVNGPARVGPGM 359
Cdd:PRK11556 322 VVIPTAALQMGNEGHFVWVLNDENKVSKHLVTPGIQDSQKVVISAGLSAGDRVVTDGIDRLTEGA 386
|
|
| PRK15030 |
PRK15030 |
multidrug efflux RND transporter periplasmic adaptor subunit AcrA; |
19-369 |
5.92e-30 |
|
multidrug efflux RND transporter periplasmic adaptor subunit AcrA;
Pssm-ID: 184990 [Multi-domain] Cd Length: 397 Bit Score: 119.05 E-value: 5.92e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 19 GCADEsapNAQQ--QQLQPIDVAQVLIKPVQSWHTYTTRLESPQEVALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERP 96
Cdd:PRK15030 24 GCDDK---QAQQggQQMPAVGVVTVKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPAT 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 97 FAAVVASLEAQIHSAEAALEQAKSEDKRAVRLLERKAISTEQAQARTSTLRQREAQLAALQAQLTSAKLDLEFTSVVSPI 176
Cdd:PRK15030 101 YQATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETARINLAYTKVTSPI 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 177 DGVISRANITKGNNVLAGQ-SVLTSIVSNKAMYayfdVDERTWNSAFNDVTAQSRQTVVMQKVGQKE----------FAY 245
Cdd:PRK15030 181 SGRIGKSNVTEGALVQNGQaTALATVQQLDPIY----VDVTQSSNDFLRLKQELANGTLKQENGKAKvslitsdgikFPQ 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 246 QGYINFIDNQINSATGTLRVRAVFEQDNNQLRAGSFARVKLAANEVSEKVIIPERAIG-TDLKNRFVLTVGENNVLEYKL 324
Cdd:PRK15030 257 DGTLEFSDVTVDQTTGSITLRAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTrTPRGDATVLVVGADDKVETRP 336
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 567929810 325 IEVGERYGALRAVTAGLNEGDIIAVNGPARVGPGMPISPNTVTID 369
Cdd:PRK15030 337 IVASQAIGDKWLVTEGLKAGDRVVISGLQKVRPGVQVKAQEVTAD 381
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
45-349 |
4.37e-28 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 112.52 E-value: 4.37e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 45 PVQSWHTYTTRLE-SPQEVALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQIHSAEAALEQAKSEDK 123
Cdd:pfam00529 3 PLTKGVEAPGRVVvSGNAKAVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAELD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 124 RAVRLLERKAISTEQAQARTSTLRQREAQLAALQAQLTSAKLDLEFTSVVSPIDGVISRANITKGNNVLAGQ-SVLTSIV 202
Cdd:pfam00529 83 RLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTAGALVAQAQaNLLATVA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 203 SNKAMYAYFDVDERTWNSAFNDVTAQSRQTVVMQKVGQKEFAYQ-----------GYINFIDNQINSATGTLRVRAVFEQ 271
Cdd:pfam00529 163 QLDQIYVQITQSAAENQAEVRSELSGAQLQIAEAEAELKLAKLDlerteirapvdGTVAFLSVTVDGGTVSAGLRLMFVV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 272 DNNQ-LRAGSFARVKLAANEVSEKVIIPERAIGTDLKNRFVLTV-GENNVLEYKLIEVGERYGALRAVTAGLNEGDIIAV 349
Cdd:pfam00529 243 PEDNlLVPGMFVETQLDQVRVGQPVLIPFDAFPQTKTGRFTGVVvGISPDTGPVRVVVDKAQGPYYPLRIGLSAGALVRL 322
|
|
| PRK09859 |
PRK09859 |
multidrug transporter subunit MdtE; |
59-359 |
1.16e-27 |
|
multidrug transporter subunit MdtE;
Pssm-ID: 137559 [Multi-domain] Cd Length: 385 Bit Score: 112.50 E-value: 1.16e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 59 PQEVA-LMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQIHSAEAALEQAKSEDKRAVRLLERKAISTE 137
Cdd:PRK09859 58 PYEVAeIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELNSAKGSLAKALSTASNARITFNRQASLLKTNYVSRQ 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 138 QAQARTSTLRQREAQLAALQAQLTSAKLDLEFTSVVSPIDGVISRANITKGNNVLAGQS-VLTSIVSNKAMYA------- 209
Cdd:PRK09859 138 DYDTARTQLNEAEANVTVAKAAVEQATINLQYANVTSPITGVSGKSSVTVGALVTANQAdSLVTVQRLDPIYVdltqsvq 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 210 -YFDVDERTWNSAFNDVTAQSrqTVVMQKVGQKEFAYQGYINFIDNQINSATGTLRVRAVFEQDNNQLRAGSFARVKLAA 288
Cdd:PRK09859 218 dFLRMKEEVASGQIKQVQGST--PVQLNLENGKRYSQTGTLKFSDPTVDETTGSVTLRAIFPNPNGDLLPGMYVTALVDE 295
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 567929810 289 NEVSEKVIIPERAIGTDLKNRFV-LTVGENNVLEYKLIEVGERYGALRAVTAGLNEGDIIAVNGPARVGPGM 359
Cdd:PRK09859 296 GSRQNVLLVPQEGVTHNAQGKATaLILDKDDVVQLREIEASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGI 367
|
|
| PRK09578 |
PRK09578 |
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit; |
19-363 |
1.03e-24 |
|
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 169982 [Multi-domain] Cd Length: 385 Bit Score: 104.11 E-value: 1.03e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 19 GCADESaPNAQQQQLQPIDVAQVLIKPVQSWHTYTTRLESPQEVALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFA 98
Cdd:PRK09578 22 GCGKGD-SDAAAAAPREATVVTVRPTSVPMTVELPGRLDAYRQAEVRARVAGIVTARTYEEGQEVKQGAVLFRIDPAPLK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 99 AVVASLEAQIHSAEAALEQAKSEDKRAVRLLERKAISTEQAQARTSTLRQREAQLAALQAQLTSAKLDLEFTSVVSPIDG 178
Cdd:PRK09578 101 AARDAAAGALAKAEAAHLAALDKRRRYDDLVRDRAVSERDYTEAVADERQAKAAVASAKAELARAQLQLDYATVTAPIDG 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 179 VISRANITKGnnVLAGQ---SVLTSIVSNKAMYAYF-----DVD--ERTWNSAFNDVTAQSRQTVVMQKVGQKEFAYQGY 248
Cdd:PRK09578 181 RARRALVTEG--ALVGQdqaTPLTTVEQLDPIYVNFsqpaaDVEalRRAVKSGRATGIAQQDVAVTLVRADGSEYPLKGK 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 249 INFIDNQINSATGTLRVRAVFEQDNNQLRAGSFARVKLAANEVSEKVIIPERAIGTDLKNRFVLTVGENNVLEYKLIEVG 328
Cdd:PRK09578 259 LLFSDLAVDPTTDTVAMRALFPNPERELLPGAYVRIALDRAVNPRAILVPRDALLRTADSASVKVVGQNGKVRDVEVEAD 338
|
330 340 350
....*....|....*....|....*....|....*
gi 567929810 329 ERYGALRAVTAGLNEGDIIAVNGPARVGPGMPISP 363
Cdd:PRK09578 339 QMSGRDWIVTRGLAGGERVIVDNAAQFAPGTAVKA 373
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
60-216 |
7.78e-22 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 95.11 E-value: 7.78e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 60 QEVALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAA---------------------------VVASLEAQIHSAE 112
Cdd:COG1566 44 RVVTVAAKVSGRVTEVLVKEGDRVKKGQVLARLDPTDLQAalaqaeaqlaaaeaqlarleaelgaeaEIAAAEAQLAAAQ 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 113 AALEQAKSEDKRAVRLLERKAISTEQ----------AQAR-----------------TSTLRQREAQLAALQAQLTSAKL 165
Cdd:COG1566 124 AQLDLAQRELERYQALYKKGAVSQQEldearaaldaAQAQleaaqaqlaqaqaglreEEELAAAQAQVAQAEAALAQAEL 203
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 567929810 166 DLEFTSVVSPIDGVISRANITKGNNVLAGQSVLTsIVSNKAMYAYFDVDER 216
Cdd:COG1566 204 NLARTTIRAPVDGVVTNLNVEPGEVVSAGQPLLT-IVPLDDLWVEAYVPET 253
|
|
| PRK11578 |
PRK11578 |
macrolide transporter subunit MacA; Provisional |
25-358 |
7.87e-12 |
|
macrolide transporter subunit MacA; Provisional
Pssm-ID: 183211 [Multi-domain] Cd Length: 370 Bit Score: 65.95 E-value: 7.87e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 25 APNAQQQQLQPIDVAQVLIKpvqswhtyTTRLESPQEVALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASL 104
Cdd:PRK11578 33 VPTYQTLIVRPGDLQQSVLA--------TGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEV 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 105 EAQIHSAEAALEQAKSEDK-------RAVRLLERKAIS--------TEQA--QARTSTLrqrEAQLAALQAQLTSAKLDL 167
Cdd:PRK11578 105 EATLMELRAQRQQAEAELKlarvtlsRQQRLAKTQAVSqqdldtaaTELAvkQAQIGTI---DAQIKRNQASLDTAKTNL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 168 EFTSVVSPIDGVISRANITKGNNVLAGQSVLTsIVSNKAMYAYFdvdertwnsafndVTAQ-SRQTVVMQKVGQKEF--- 243
Cdd:PRK11578 182 DYTRIVAPMAGEVTQITTLQGQTVIAAQQAPN-ILTLADMSTML-------------VKAQvSEADVIHLKPGQKAWftv 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 244 ------AYQGYINFI---DNQINSAtgtLRVRAVFEQDNNQ--LRAGSFARVKLAANEVSEKVIIPERAIGTDL-KNRFV 311
Cdd:PRK11578 248 lgdpltRYEGVLKDIlptPEKVNDA---IFYYARFEVPNPNglLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVgDNRYK 324
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 567929810 312 LTVGENNVLEYKLIEVGERYGALRAVTAGLNEGDIIAVngpARVGPG 358
Cdd:PRK11578 325 VKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVII---GEAKPG 368
|
|
| PRK03598 |
PRK03598 |
putative efflux pump membrane fusion protein; Provisional |
61-199 |
4.42e-11 |
|
putative efflux pump membrane fusion protein; Provisional
Pssm-ID: 235136 [Multi-domain] Cd Length: 331 Bit Score: 63.44 E-value: 4.42e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 61 EVALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFA-------AVVASLEAQ-------------------IHSAEAA 114
Cdd:PRK03598 43 TVNLGFRVGGRLASLAVDEGDAVKAGQVLGELDAAPYEnalmqakANVSVAQAQldlmlagyrdeeiaqaraaVKQAQAA 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 115 LEQAKSEDKRAVRLLERKAIST----------EQAQAR----TSTLRQREA------------QLAALQAQLTSAKLDLE 168
Cdd:PRK03598 123 YDYAQNFYNRQQGLWKSRTISAndlenarssrDQAQATlksaQDKLSQYREgnrpqdiaqakaSLAQAQAALAQAELNLQ 202
|
170 180 190
....*....|....*....|....*....|..
gi 567929810 169 FTSVVSPIDGVI-SRAnITKGNNVLAGQSVLT 199
Cdd:PRK03598 203 DTELIAPSDGTIlTRA-VEPGTMLNAGSTVFT 233
|
|
| PRK10559 |
PRK10559 |
p-hydroxybenzoic acid efflux pump subunit AaeA; |
38-193 |
8.00e-11 |
|
p-hydroxybenzoic acid efflux pump subunit AaeA;
Pssm-ID: 182548 [Multi-domain] Cd Length: 310 Bit Score: 62.45 E-value: 8.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 38 VAQVLIKPVQSWHTYTtrlESPQE---------VALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQI 108
Cdd:PRK10559 18 VILAFIAIFRAWVFYT---ESPWTrdarfsadvVAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALAEAEADV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 109 HSAEAALEQAKSEDKRAVRLLERkAISTEQAQARTSTLRQREAQLAALQAQLTSAKLDLEFTSVVSPIDGVISRAN---- 184
Cdd:PRK10559 95 AYYQVLAQEKRREAGRRNRLGVQ-AMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNvytg 173
|
170
....*....|.
gi 567929810 185 --ITKGNNVLA 193
Cdd:PRK10559 174 efITRGSTAVA 184
|
|
| PRK10476 |
PRK10476 |
multidrug transporter subunit MdtN; |
66-201 |
6.49e-10 |
|
multidrug transporter subunit MdtN;
Pssm-ID: 182488 [Multi-domain] Cd Length: 346 Bit Score: 60.04 E-value: 6.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 66 PRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQIHSAEAAL---------------------EQAKSEDKR 124
Cdd:PRK10476 53 SEVGGRIVELAVTENQAVKKGDLLFRIDPRPYELTVAQAQADLALADAQImttqrsvdaersnaasaneqvERARANAKL 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 125 AVRLLERKA-------ISTEQA-QARTS----------TLRQREAQLAALQAQLTS-------------AKLDLEFTSVV 173
Cdd:PRK10476 133 ATRTLERLEpllakgyVSAQQVdQARTAqrdaevslnqALLQAQAAAAAVGGVDALvaqraareaalaiAELHLEDTTVR 212
|
170 180
....*....|....*....|....*...
gi 567929810 174 SPIDGVISRANITKGNNVLAGQSVLTSI 201
Cdd:PRK10476 213 APFDGRVVGLKVSVGEFAAPMQPIFTLI 240
|
|
| Biotin_lipoyl_2 |
pfam13533 |
Biotin-lipoyl like; |
62-108 |
9.87e-08 |
|
Biotin-lipoyl like;
Pssm-ID: 433286 Cd Length: 50 Bit Score: 48.21 E-value: 9.87e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 567929810 62 VALMPRVSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQI 108
Cdd:pfam13533 3 VKIASPVSGKVVAVNVKEGQQVKKGDVLATLDSPELQLQLQQAEAQL 49
|
|
| HlyD_D23 |
pfam16576 |
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and ... |
66-282 |
1.42e-07 |
|
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.
Pssm-ID: 435440 [Multi-domain] Cd Length: 214 Bit Score: 51.74 E-value: 1.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 66 PRVSGVIDSIEFK-EGDVVKQGDVLFQLDerpfaavvaSLEaqIHSAEAALEQAKSEDKRAVRLLERKA---------IS 135
Cdd:pfam16576 24 ARVEGWIEKLYVNaTGDPVKKGQPLAELY---------SPE--LVAAQQEYLLALRSGDALSKSELLRAarqrlrllgMP 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 136 TEQ--AQARTSTLRQReaqlaalqaqltsakldlefTSVVSPIDGVISRANITKGNNVLAGQSVLTsIVSNKAMYAYFDV 213
Cdd:pfam16576 93 EAQiaELERTGKVQPT--------------------VTVYAPISGVVTELNVREGMYVQPGDTLFT-IADLSTVWVEADV 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 567929810 214 DERTwnsaFNDVTAQSRQTVVMQKVGQKEFayQGYINFIDNQINSATGTLRVRAVFEQDNNQLRAGSFA 282
Cdd:pfam16576 152 PEQD----LALVKVGQPAEVTLPALPGKTF--EGKVDYIYPTLDPKTRTVRVRIELPNPDGRLKPGMFA 214
|
|
| PRK15136 |
PRK15136 |
multidrug efflux MFS transporter periplasmic adaptor subunit EmrA; |
61-193 |
3.50e-07 |
|
multidrug efflux MFS transporter periplasmic adaptor subunit EmrA;
Pssm-ID: 185090 [Multi-domain] Cd Length: 390 Bit Score: 51.62 E-value: 3.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 61 EVALMPRVSGVIDSIEFKEGDVVKQGDVLFQLD--------ERPFAAVVAS-------------LEAQIHSAEAALEQAK 119
Cdd:PRK15136 61 QVQIMSQVSGSVTKVWADNTDFVKEGDVLVTLDptdaeqafEKAKTALANSvrqthqlminskqYQANIELQKTALAQAQ 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 120 SEDKRAVRLLERKAISTEQ----------AQARTSTLRQ---------------REAQLAALQAQLTSAKLDLEFTSVVS 174
Cdd:PRK15136 141 SDLNRRVPLGNANLIGREElqhardavasAQAQLDVAIQqynanqamilntpleDQPAVQQAATEVRNAWLALQRTKIVS 220
|
170 180
....*....|....*....|....*
gi 567929810 175 PIDGVISR------ANITKGNNVLA 193
Cdd:PRK15136 221 PMTGYVSRrsvqvgAQISPTTPLMA 245
|
|
| HlyD_3 |
pfam13437 |
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator ... |
172-279 |
2.90e-05 |
|
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator HlyD proteins.
Pssm-ID: 433206 [Multi-domain] Cd Length: 104 Bit Score: 42.73 E-value: 2.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 172 VVSPIDGVISRANITKGNNVLAGQSVLTsIVSNKAMYAYFDVDERTWNSafndVTAQsrQTVVMQKVGQKEFAYQGYINF 251
Cdd:pfam13437 2 IRAPVDGVVAELNVEEGQVVQAGDPLAT-IVPPDRLLVEAFVPAADLGS----LKKG--QKVTLKLDPGSDYTLEGKVVR 74
|
90 100 110
....*....|....*....|....*....|
gi 567929810 252 IDNQINSATGTLRVRAVFEQDNNQ--LRAG 279
Cdd:pfam13437 75 ISPTVDPDTGVIPVRVSIENPKTPipLLPG 104
|
|
| PRK09783 |
PRK09783 |
copper/silver efflux system membrane fusion protein CusB; Provisional |
161-351 |
5.50e-05 |
|
copper/silver efflux system membrane fusion protein CusB; Provisional
Pssm-ID: 236625 [Multi-domain] Cd Length: 409 Bit Score: 44.86 E-value: 5.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 161 TSAKLDLEFTsVVSPIDGVISRANITKGNNVlAGQSVLTSIVSNKAMYAYFDVDErtwnSAFNDVTAQSRQTVVMQKVGQ 240
Cdd:PRK09783 202 ATRKIQTRFT-LKAPIDGVITAFDLRAGMNI-AKDNVVAKIQGMDPVWVTAAIPE----SIAWLVKDASQFTLTVPARPD 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567929810 241 KEFAYQGYInfIDNQINSATGTLRVRAVFEQDNNQLRAGSFARVKLAAnEVSEKVIIPERAIGTDLKNRFVLTVGENNVL 320
Cdd:PRK09783 276 KTFTIRKWT--LLPSVDAATRTLQLRLEVDNADEALKPGMNAWLQLNT-ASEPMLLIPSQALIDTGSEQRVITVDADGRF 352
|
170 180 190
....*....|....*....|....*....|.
gi 567929810 321 EYKLIEVGERYGALRAVTAGLNEGDIIAVNG 351
Cdd:PRK09783 353 VPKRVAVFQESQGVTAIRSGLAEGEKVVSSG 383
|
|
| sucB |
TIGR01347 |
2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); This ... |
68-121 |
9.16e-04 |
|
2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); This model describes the TCA cycle 2-oxoglutarate system E2 component, dihydrolipoamide succinyltransferase. It is closely related to the pyruvate dehydrogenase E2 component, dihydrolipoamide acetyltransferase. The seed for this model includes mitochondrial and Gram-negative bacterial forms. Mycobacterial candidates are highly derived, differ in having and extra copy of the lipoyl-binding domain at the N-terminus. They score below the trusted cutoff, but above the noise cutoff and above all examples of dihydrolipoamide acetyltransferase. [Energy metabolism, TCA cycle]
Pssm-ID: 273565 [Multi-domain] Cd Length: 403 Bit Score: 41.26 E-value: 9.16e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 567929810 68 VSGVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQIHSAEAALEQAKSE 121
Cdd:TIGR01347 50 ADGVLQEILFKEGDTVESGQVLAILEEGNDATAAPPAKSGEEKEETPAASAAAA 103
|
|
| type_I_hlyD |
TIGR01843 |
type I secretion membrane fusion protein, HlyD family; Type I secretion is an ABC transport ... |
70-121 |
2.25e-03 |
|
type I secretion membrane fusion protein, HlyD family; Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 130902 [Multi-domain] Cd Length: 423 Bit Score: 39.99 E-value: 2.25e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 567929810 70 GVIDSIEFKEGDVVKQGDVLFQLDERPFAAVVASLEAQIHSAEAALEQAKSE 121
Cdd:TIGR01843 52 GIVREILVREGDRVKAGQVLVELDATDVEADAAELESQVLRLEAEVARLRAE 103
|
|
| PRK11855 |
PRK11855 |
dihydrolipoamide acetyltransferase; Reviewed |
68-118 |
2.92e-03 |
|
dihydrolipoamide acetyltransferase; Reviewed
Pssm-ID: 237000 [Multi-domain] Cd Length: 547 Bit Score: 39.81 E-value: 2.92e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 567929810 68 VSGVIDSIEFKEGDVVKQGDVLFQLD-ERPFAAVVASLEAQIHSAEAALEQA 118
Cdd:PRK11855 168 VAGVVKEIKVKVGDKVSVGSLLVVIEvAAAAPAAAAAPAAAAPAAAAAAAPA 219
|
|
| |
