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Conserved domains on  [gi|636784560|ref|WP_024320773|]
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lytic transglycosylase domain-containing protein [Rhizobium ruizarguesonis]

Protein Classification

lytic transglycosylase domain-containing protein( domain architecture ID 11432856)

lytic transglycosylase domain-containing protein similar to Bacillus subtilis bifunctional muramidase/lytic transglycosylase CwlQ that cleaves the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine (MurNAc-GlcNAc) in peptidoglycan, producing both N-acetylmuramic acid and 1,6-anhydro-N-acetylmuramic acid

Gene Ontology:  GO:0016787|GO:0000270|GO:0008933|GO:0071555
PubMed:  8765311|7479697|9723170

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MltE COG0741
Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin ...
 20-172 2.33e-38

Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin domain) [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440504 [Multi-domain]  Cd Length: 244  Bit Score: 131.27  E-value: 2.33e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  20 SFALANDDWGARAETISLKTVDRQSGYAmPDFSTSTPYASLINKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLM 99
Cdd:COG0741   67 AAALAAADALAAFAAIAALAAELLALAA-LLLRRPLPYLPLIEEAAKKYGVDPALVLALIRQESAFNPNAVSPAGARGLM 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560 100 QIKPATARMMGYSG----SRKGLFDPETNIKYGMKYLAAAHQLGGGQTCNTILKYNAGHAATR------------MNPVS 163
Cdd:COG0741  146 QLMPATARRLGLKLglgpSPDDLFDPETNIRAGAAYLRELLDRFDGDLVLALAAYNAGPGRVRrwlrrngdrdgeIIPYA 225

                        170
                 ....*....|.
gi 636784560 164 KT--YCGKVLA 172
Cdd:COG0741  226 ETrnYVKKVLA 236
 
Name Accession Description Interval E-value
MltE COG0741
Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin ...
 20-172 2.33e-38

Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin domain) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440504 [Multi-domain]  Cd Length: 244  Bit Score: 131.27  E-value: 2.33e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  20 SFALANDDWGARAETISLKTVDRQSGYAmPDFSTSTPYASLINKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLM 99
Cdd:COG0741   67 AAALAAADALAAFAAIAALAAELLALAA-LLLRRPLPYLPLIEEAAKKYGVDPALVLALIRQESAFNPNAVSPAGARGLM 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560 100 QIKPATARMMGYSG----SRKGLFDPETNIKYGMKYLAAAHQLGGGQTCNTILKYNAGHAATR------------MNPVS 163
Cdd:COG0741  146 QLMPATARRLGLKLglgpSPDDLFDPETNIRAGAAYLRELLDRFDGDLVLALAAYNAGPGRVRrwlrrngdrdgeIIPYA 225

                        170
                 ....*....|.
gi 636784560 164 KT--YCGKVLA 172
Cdd:COG0741  226 ETrnYVKKVLA 236
LT_Slt70-like cd16896
uncharacterized lytic transglycosylase subfamily with similarity to Slt70; Uncharacterized ...
 56-158 8.73e-33

uncharacterized lytic transglycosylase subfamily with similarity to Slt70; Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.


Pssm-ID: 381617 [Multi-domain]  Cd Length: 146  Bit Score: 114.14  E-value: 8.73e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  56 PYASLINKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATAR----MMGYSGSRKG-LFDPETNIKYGMK 130
Cdd:cd16896    3 KYREYIEKYAKEYGVDPLLVAAVIKVESNFNPNAVSSKGAIGLMQIMPETAEwiaeKLGLEDFSEDdLYDPETNIRLGTW 82

                         90       100
                 ....*....|....*....|....*...
gi 636784560 131 YLAAAHQLGGGQTCNTILKYNAGHAATR 158
Cdd:cd16896   83 YLSYLLKEFDGNLVLALAAYNAGPGNVD 110
SLT pfam01464
Transglycosylase SLT domain; This family is distantly related to pfam00062. Members are found ...
 61-158 1.34e-22

Transglycosylase SLT domain; This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.


Pssm-ID: 396169 [Multi-domain]  Cd Length: 114  Bit Score: 86.98  E-value: 1.34e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560   61 INKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATARMMGYSGSRK--GLFDPETNIKYGMKYLAAAHQL 138
Cdd:pfam01464   1 IIKAAQKYGVDPSLLLAIAQQESGFNPKAVSKSGAVGLMQIMPSTAKRLGLRVNPGvdDLFDPEKNIKAGTKYLKELYKQ 80

                          90       100
                  ....*....|....*....|
gi 636784560  139 GGGQTCNTILKYNAGHAATR 158
Cdd:pfam01464  81 YGGDLWLALAAYNAGPGRVR 100
PRK11619 PRK11619
lytic murein transglycosylase; Provisional
 57-153 3.13e-17

lytic murein transglycosylase; Provisional


Pssm-ID: 183236 [Multi-domain]  Cd Length: 644  Bit Score: 78.18  E-value: 3.13e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  57 YASLINKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATAR-------MMGYSGSRKgLFDPETNIKYGM 129
Cdd:PRK11619 479 WNDEFRRYTSGKGIPQSYAMAIARQESAWNPKARSPVGASGLMQIMPGTAThtvkmfsIPGYSSSSQ-LLDPETNINIGT 557

                         90       100
                 ....*....|....*....|....*..
gi 636784560 130 KYLAAAHQLGGGqtcNTILK---YNAG 153
Cdd:PRK11619 558 SYLEYVYQQFGN---NRILAsaaYNAG 581
 
Name Accession Description Interval E-value
MltE COG0741
Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin ...
 20-172 2.33e-38

Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin domain) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440504 [Multi-domain]  Cd Length: 244  Bit Score: 131.27  E-value: 2.33e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  20 SFALANDDWGARAETISLKTVDRQSGYAmPDFSTSTPYASLINKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLM 99
Cdd:COG0741   67 AAALAAADALAAFAAIAALAAELLALAA-LLLRRPLPYLPLIEEAAKKYGVDPALVLALIRQESAFNPNAVSPAGARGLM 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560 100 QIKPATARMMGYSG----SRKGLFDPETNIKYGMKYLAAAHQLGGGQTCNTILKYNAGHAATR------------MNPVS 163
Cdd:COG0741  146 QLMPATARRLGLKLglgpSPDDLFDPETNIRAGAAYLRELLDRFDGDLVLALAAYNAGPGRVRrwlrrngdrdgeIIPYA 225

                        170
                 ....*....|.
gi 636784560 164 KT--YCGKVLA 172
Cdd:COG0741  226 ETrnYVKKVLA 236
LT_Slt70-like cd16896
uncharacterized lytic transglycosylase subfamily with similarity to Slt70; Uncharacterized ...
 56-158 8.73e-33

uncharacterized lytic transglycosylase subfamily with similarity to Slt70; Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.


Pssm-ID: 381617 [Multi-domain]  Cd Length: 146  Bit Score: 114.14  E-value: 8.73e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  56 PYASLINKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATAR----MMGYSGSRKG-LFDPETNIKYGMK 130
Cdd:cd16896    3 KYREYIEKYAKEYGVDPLLVAAVIKVESNFNPNAVSSKGAIGLMQIMPETAEwiaeKLGLEDFSEDdLYDPETNIRLGTW 82

                         90       100
                 ....*....|....*....|....*...
gi 636784560 131 YLAAAHQLGGGQTCNTILKYNAGHAATR 158
Cdd:cd16896   83 YLSYLLKEFDGNLVLALAAYNAGPGNVD 110
LT_MltC_MltE cd16893
membrane-bound lytic murein transglycosylases MltC and MltE, and similar proteins; MltC and ...
 59-167 2.70e-26

membrane-bound lytic murein transglycosylases MltC and MltE, and similar proteins; MltC and MltE are periplasmic, outer membrane attached lytic transglycosylases (LTs), which cleave beta-1,4-glycosidic bonds joining N-acetylmuramic acid and N-acetylglucosamine in the cell wall peptidoglycan, yielding 1,6-anhydromuropeptides. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda


Pssm-ID: 381614 [Multi-domain]  Cd Length: 162  Bit Score: 98.01  E-value: 2.70e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  59 SLINKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATA-----RMMGYSG---SRKGLFDPETNIKYGMK 130
Cdd:cd16893    1 PIVEKYAKKYGVDPALILAIIETESSFNPYAVSHSPAYGLMQIVPSTAgrdvyRLLGGKGglpSKSYLFDPENNIDIGTA 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 636784560 131 YLAaahqlgggqtcntILKYNAGHAATrmNPVSKTYC 167
Cdd:cd16893   81 YLH-------------ILQNRYLKGIK--NPKSREYC 102
Slt70-like cd13401
70kDa soluble lytic transglycosylase (Slt70) and similar proteins; Catalytic domain of the ...
 55-133 4.52e-26

70kDa soluble lytic transglycosylase (Slt70) and similar proteins; Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.


Pssm-ID: 381604 [Multi-domain]  Cd Length: 152  Bit Score: 96.78  E-value: 4.52e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  55 TPYASLINKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATARMM------GYSGSRKgLFDPETNIKYG 128
Cdd:cd13401    4 LPYRDLVERAAKKNGLDPALVYAIIRQESAFDPDAVSPAGALGLMQLMPATAKDVakklglPYYSPRD-LFDPEYNIRLG 82


                 ....*
gi 636784560 129 MKYLA 133
Cdd:cd13401   83 SAYLA 87
LT-like cd00254
lytic transglycosylase(LT)-like domain; Members include the soluble and insoluble ...
 73-158 2.50e-24

lytic transglycosylase(LT)-like domain; Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.


Pssm-ID: 381594 [Multi-domain]  Cd Length: 111  Bit Score: 91.12  E-value: 2.50e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  73 ALAQAVVRVESNFNPNARGSAGEVGLMQIKPATARMMGYSGSRKgLFDPETNIKYGMKYLAAAHQLGGGQTCNTILKYNA 152
Cdd:cd00254    2 ALVLAVIRVESGFNPRAVSPAGARGLMQLMPGTARDLGRRGVDD-LFDPEENIRAGARYLRELLDRFGGDLELALAAYNA 80


                 ....*.
gi 636784560 153 GHAATR 158
Cdd:cd00254   81 GPGAVD 86
SLT pfam01464
Transglycosylase SLT domain; This family is distantly related to pfam00062. Members are found ...
 61-158 1.34e-22

Transglycosylase SLT domain; This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.


Pssm-ID: 396169 [Multi-domain]  Cd Length: 114  Bit Score: 86.98  E-value: 1.34e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560   61 INKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATARMMGYSGSRK--GLFDPETNIKYGMKYLAAAHQL 138
Cdd:pfam01464   1 IIKAAQKYGVDPSLLLAIAQQESGFNPKAVSKSGAVGLMQIMPSTAKRLGLRVNPGvdDLFDPEKNIKAGTKYLKELYKQ 80

                          90       100
                  ....*....|....*....|
gi 636784560  139 GGGQTCNTILKYNAGHAATR 158
Cdd:pfam01464  81 YGGDLWLALAAYNAGPGRVR 100
MltF COG4623
Membrane-bound lytic murein transglycosylase MltF [Cell wall/membrane/envelope biogenesis, ...
 42-133 4.91e-19

Membrane-bound lytic murein transglycosylase MltF [Cell wall/membrane/envelope biogenesis, Signal transduction mechanisms];


Pssm-ID: 443662 [Multi-domain]  Cd Length: 421  Bit Score: 82.80  E-value: 4.91e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  42 RQSGYAMPDFSTSTPYASLINKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATARMMGYsgsrKGLFDP 121
Cdd:COG4623  249 DTRAFLRRIEGRLPPYDPLFEKYAEEYGLDWRLLAALAYQESHWNPRARSPTGARGLMQLMPATAKELGV----DDRLDP 324

                         90
                 ....*....|..
gi 636784560 122 ETNIKYGMKYLA 133
Cdd:COG4623  325 EQSIRAGAKYLR 336
MLTF-like cd13403
membrane-bound lytic murein transglycosylase F (MLTF) and similar proteins; This subfamily ...
 63-133 2.17e-18

membrane-bound lytic murein transglycosylase F (MLTF) and similar proteins; This subfamily includes membrane-bound lytic murein transglycosylase F (MltF, murein lyase F) that degrades murein glycan strands. It is responsible for catalyzing the release of 1,6-anhydromuropeptides from peptidoglycan. Lytic transglycosylase catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc) as do goose-type lysozymes. However, in addition, it also makes a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.


Pssm-ID: 381606 [Multi-domain]  Cd Length: 161  Bit Score: 77.19  E-value: 2.17e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 636784560  63 KYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATARMMGYSgsrkGLFDPETNIKYGMKYLA 133
Cdd:cd13403    3 KYAEKYGFDWRLLAAQAYQESRFNPNARSPAGARGLMQLMPSTARELGVN----DRLDPEQNIHAGAKYLR 69
PRK11619 PRK11619
lytic murein transglycosylase; Provisional
 57-153 3.13e-17

lytic murein transglycosylase; Provisional


Pssm-ID: 183236 [Multi-domain]  Cd Length: 644  Bit Score: 78.18  E-value: 3.13e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  57 YASLINKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATAR-------MMGYSGSRKgLFDPETNIKYGM 129
Cdd:PRK11619 479 WNDEFRRYTSGKGIPQSYAMAIARQESAWNPKARSPVGASGLMQIMPGTAThtvkmfsIPGYSSSSQ-LLDPETNINIGT 557

                         90       100
                 ....*....|....*....|....*..
gi 636784560 130 KYLAAAHQLGGGqtcNTILK---YNAG 153
Cdd:PRK11619 558 SYLEYVYQQFGN---NRILAsaaYNAG 581
mltC PRK11671
membrane-bound lytic murein transglycosylase MltC;
57-133 3.83e-15

membrane-bound lytic murein transglycosylase MltC;


Pssm-ID: 183271 [Multi-domain]  Cd Length: 359  Bit Score: 71.62  E-value: 3.83e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  57 YASLINKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATA-----RMMGYSG--SRKGLFDPETNIKYGM 129
Cdd:PRK11671 192 YLPMVRKASRKYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTAgkdvfRMKGKSGqpSRSYLFDPANNIDTGT 271


                 ....
gi 636784560 130 KYLA 133
Cdd:PRK11671 272 AYLA 275
Slt35-like cd13399
Slt35-like lytic transglycosylase; Lytic transglycosylase similar to Escherichia coli lytic ...
 68-153 2.84e-12

Slt35-like lytic transglycosylase; Lytic transglycosylase similar to Escherichia coli lytic transglycosylase Slt35 and Pseudomonas aeruginosa Sltb1. Lytic transglycosylase (LT) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc) as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).


Pssm-ID: 381602 [Multi-domain]  Cd Length: 108  Bit Score: 60.01  E-value: 2.84e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  68 YNVPVALAQAVVRVESNFNPNARGS-AGEVGLMQIKPATARMMGYSGSRKG---LFDPETNIKYGMKYLAA----AHQLG 139
Cdd:cd13399    1 YGVPPGILAAILGVESGFGPNAGGSpAGAQGIAQFMPSTWKAYGVDGNGDGkadPFNPEDAIASAANYLCRhgwdLNAFL 80

                         90
                 ....*....|....
gi 636784560 140 GGQTCNTILKYNAG 153
Cdd:cd13399   81 GEDNFLALAAYNAG 94
emtA PRK15470
membrane-bound lytic murein transglycosylase EmtA;
63-133 1.20e-10

membrane-bound lytic murein transglycosylase EmtA;


Pssm-ID: 185367 [Multi-domain]  Cd Length: 203  Bit Score: 57.67  E-value: 1.20e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 636784560  63 KYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATA-----RMMGYSG--SRKGLFDPETNIKYGMKYLA 133
Cdd:PRK15470  45 KAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSgrdvyRRMGWSGepTTSELKNPERNISMGAAYLN 122
MltD-like cd16894
Membrane-bound lytic murein transglycosylase D and similar proteins; Lytic transglycosylases ...
 66-166 4.61e-10

Membrane-bound lytic murein transglycosylase D and similar proteins; Lytic transglycosylases (LT) catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc). Membrane-bound lytic murein transglycosylase D protein (MltD) family members may have one or more small LysM domains, which may contribute to peptidoglycan binding. Unlike the similar "goose-type" lysozymes, LTs also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).


Pssm-ID: 381615 [Multi-domain]  Cd Length: 129  Bit Score: 54.45  E-value: 4.61e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  66 AEYNVPVALAqAVVRVESNFNPNARGSAGEVGLMQIKPATARMMG--YSGSRKGLFDPETNIKYGMKYLAAAHQLGGGQT 143
Cdd:cd16894    2 LKEGLPEELK-YLALVESGFNPDAVSSAGAAGLWQFMPATAREYGlrVDSWVDERRDPEKSTRAAARYLKDLYKRFGDWL 80

                         90       100
                 ....*....|....*....|....*..
gi 636784560 144 CnTILKYNAGHA----ATRMNPVSKTY 166
Cdd:cd16894   81 L-ALAAYNAGEGrvrrAIKRAGTDKWE 106
PHA00368 PHA00368
internal virion protein D
 55-153 3.13e-08

internal virion protein D


Pssm-ID: 222785 [Multi-domain]  Cd Length: 1315  Bit Score: 52.09  E-value: 3.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560   55 TPYASLINKYAAEYNVPVALAQAVVRVESNFNPNARGSAGEVGLMQIKPATARMMGYSGSRKGLFDPETNIKYGMKYLAA 134
Cdd:PHA00368    9 SEYDGLFQKAADAHGVSYDLLRKVGWDESRFNPTAKSPTGPKGLMQFTKATAKALGLIVDDDDRLDPELAIDAGARYLAD 88

                          90
                  ....*....|....*....
gi 636784560  135 AHQLGGGQTCNTILKYNAG 153
Cdd:PHA00368   89 LVGKYDGDELKAALAYNQG 107
LT_IagB-like cd13400
Escherichia coli invasion protein IagB and similar proteins; Lytic transglycosylase-like ...
 68-133 4.62e-08

Escherichia coli invasion protein IagB and similar proteins; Lytic transglycosylase-like protein, similar to Escherichia coli invasion protein IagB. IagB is encoded within a pathogenicity island in Salmonella enterica and has been shown to degrade polymeric peptidoglycan. IagB-like invasion proteins are implicated in the invasion of eukaryotic host cells by bacteria. Lytic transglycosylase (LT) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Members of this family resemble the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.


Pssm-ID: 381603 [Multi-domain]  Cd Length: 109  Bit Score: 48.68  E-value: 4.62e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 636784560  68 YNVPVALAQAVVRVESNFNPNA--RGSAG--EVGLMQI----KPATARmMGYSGSRKgLFDPETNIKYGMKYLA 133
Cdd:cd13400    1 YGVPPRLLRAIAKVESGFNPNAinRNKNGsyDIGLMQInsiwLPELAR-YGITREEL-LNDPCTNIYVGAWILA 72
PRK10859 PRK10859
membrane-bound lytic murein transglycosylase MltF;
57-133 6.51e-06

membrane-bound lytic murein transglycosylase MltF;


Pssm-ID: 236778 [Multi-domain]  Cd Length: 482  Bit Score: 45.25  E-value: 6.51e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 636784560  57 YASLINKYAAEYNVPVaLAqAVVRVESNFNPNARGSAGEVGLMQIKPATARMMGYSgSRkglFDPETNIKYGMKYLA 133
Cdd:PRK10859 290 YQPLFEKYAGELDWRL-LA-AIAYQESHWNPQATSPTGVRGLMMLTRNTAQSMGVT-DR---LDPEQSIRGGARYLQ 360
CwlT-like cd16891
CwlT-like N-terminal lysozyme domain and similar domains; CwlT is a bifunctional cell wall ...
 57-155 1.01e-05

CwlT-like N-terminal lysozyme domain and similar domains; CwlT is a bifunctional cell wall hydrolase containing an N-terminal lysozyme domain and a C-terminal NlpC/P60 endopeptidase domain (gamma-d-D-glutamyl-L-diamino acid endopeptidase), and has been implicated in the spread of transposons. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).


Pssm-ID: 381612 [Multi-domain]  Cd Length: 151  Bit Score: 43.36  E-value: 1.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  57 YASLINKYAAEYNVP--VALAQAVVRVESnfnpnaRGSAGEVglMQIKPatarmmGYSGSRKGLFDPETNIKYGMKYLAA 134
Cdd:cd16891    1 YRPLVEKEAKKYGIPeyVPLILAIIMQES------GGKGPDI--MQSSE------SAGLPPNTITDPEESIEQGVKYFAD 66

                         90       100
                 ....*....|....*....|....
gi 636784560 135 AHQLGGGQTCN--TILK-YNAGHA 155
Cdd:cd16891   67 VLKKAKGKGVDiwTAVQaYNFGGG 90
mltD PRK10783
membrane-bound lytic murein transglycosylase D; Provisional
 56-115 7.98e-05

membrane-bound lytic murein transglycosylase D; Provisional


Pssm-ID: 182727 [Multi-domain]  Cd Length: 456  Bit Score: 42.03  E-value: 7.98e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 636784560  56 PYASLINKYAAEYNVPVALAQAVVrVESNFNPNARGSAGEVGLMQIKPATARMMG------YSGSR 115
Cdd:PRK10783 103 PYMYWIVGQIKKRNMPMELVLLPI-VESAFDPHATSGANAAGIWQIIPSTGRNYGlkqtrwYDARR 167
Lyz-like cd00442
lysozyme-like domains; This family contains several members, including soluble lytic ...
 77-131 8.03e-04

lysozyme-like domains; This family contains several members, including soluble lytic transglycosylases (SLT), goose egg-white lysozymes (GEWL), hen egg-white lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, chitosanases, and pesticin. Typical members are involved in the hydrolysis of beta-1,4- linked polysaccharides.


Pssm-ID: 381596 [Multi-domain]  Cd Length: 59  Bit Score: 36.23  E-value: 8.03e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 636784560  77 AVVRVESNFNPNARGS--AGEVGLMQIKPATARMMGYSgSRKGLFDPETNIKYGMKY 131
Cdd:cd00442    4 AIIGQESGGNKPANAGsgSGAAGLFQFMPGTWKAYGKN-SSSDLNDPEASIEAAAKY 59
PRK15328 PRK15328
type III secretion system invasion protein IagB;
52-170 6.06e-03

type III secretion system invasion protein IagB;


Pssm-ID: 185228 [Multi-domain]  Cd Length: 160  Bit Score: 35.61  E-value: 6.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636784560  52 STSTPYASLINKYAAEYNVPVALAQAVVRVESNFNPNA----RGSAGEVGLMQIKPA---TARMMGYSgSRKGLFDPETN 124
Cdd:PRK15328  13 SINTAWADCWLQAEKMFNIESELLYAIAQQESAMKPGAighnRDGSTDLGLMQINSFhmkRLKKMGIS-EKQLLQDPCIS 91

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 636784560 125 IKYGMKYLAAAHQLgGGQTCNTILKYNAGHAATRmNPVSKTYCGKV 170
Cdd:PRK15328  92 VIVGASILSDMMKI-YGYSWEAVGAYNAGTSPKR-SDIRKRYAKKI 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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