|
Name |
Accession |
Description |
Interval |
E-value |
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-513 |
2.03e-127 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 381.72 E-value: 2.03e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKEiLFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG--SVYYLPQILEQFDTQSIA 81
Cdd:COG0488 1 LENLSKSFGGRP-LLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKglRIGYLPQEPPLDDDLTVL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 -RALGVQKKLSALREILEGIVTEENITVLD--------------DNWDLEEKIKQALETWGLLDFTADESMNRLSGGQKT 146
Cdd:COG0488 80 dTVLDGDAELRALEAELEELEAKLAEPDEDlerlaelqeefealGGWEAEARAEEILSGLGFPEEDLDRPVSELSGGWRR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 147 KVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLLN-LLPKTAELSRKEMMLYGGNYDSYKE 225
Cdd:COG0488 160 RVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKNYPGTVLVVSHDRYFLDrVATRILELDRGKLTLYPGNYSAYLE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 226 QKQIQQnalqnsikntenalkkakATERETLERQQKldakgKKKQEKAGVAKimmntLRNNAenSTAKirdthsdKIEGL 305
Cdd:COG0488 240 QRAERL------------------EQEAAAYAKQQK-----KIAKEEEFIRR-----FRAKA--RKAK-------QAQSR 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 306 SQELQQLRRGVP--LTDQMKLGFDQANlHRGKILIKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKL 383
Cdd:COG0488 283 IKALEKLEREEPprRDKTVEIRFPPPE-RLGKKVLELEGLSKSYGDKTLLDD-LSLRIDRGDRIGLIGPNGAGKSTLLKL 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 384 LLGQMKPSEGTIERAD-FNSVYIDQDYSMINHSLSVIQqaesfnWL-----PLPEHEVKTILSRFLFGKETWDKSCSVLS 457
Cdd:COG0488 361 LAGELEPDSGTVKLGEtVKIGYFDQHQEELDPDKTVLD------ELrdgapGGTEQEVRGYLGRFLFSGDDAFKPVGVLS 434
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 458 GGERMRLLLACLSItgKAPDIIILDEPTNNLDLQNIEILTNAIRDYKGTLLVISHD 513
Cdd:COG0488 435 GGEKARLALAKLLL--SPPNVLLLDEPTNHLDIETLEALEEALDDFPGTVLLVSHD 488
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
3-527 |
1.74e-64 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 219.42 E-value: 1.74e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 3 TLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIR-TEG-SVYYLPQilE-QFDTQS 79
Cdd:TIGR03719 6 TMNRVSKVVPPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARpQPGiKVGYLPQ--EpQLDPTK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 80 IAR---ALGVQKKLSALREI-------------LEGIVTE----ENITVLDDNWDLEEKIKQALETWGLLDFTADesMNR 139
Cdd:TIGR03719 84 TVRenvEEGVAEIKDALDRFneisakyaepdadFDKLAAEqaelQEIIDAADAWDLDSQLEIAMDALRCPPWDAD--VTK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 140 LSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLL-NLLPKTAELSRKEMMLYGG 218
Cdd:TIGR03719 162 LSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHLQEYPGTVVAVTHDRYFLdNVAGWILELDRGRGIPWEG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 219 NYDSYKEQKqiqQNALQNSIKnTENALKKAKATERETLeRQqklDAKGKKKQEKAGVAkimmntlrnnaenstakirdth 298
Cdd:TIGR03719 242 NYSSWLEQK---QKRLEQEEK-EESARQKTLKRELEWV-RQ---SPKGRQAKSKARLA---------------------- 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 299 sdKIEGLSQELQQLRRGvplTDQMklgFDQANLHRGKILIKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKT 378
Cdd:TIGR03719 292 --RYEELLSQEFQKRNE---TAEI---YIPPGPRLGDKVIEAENLTKAFGDKLLIDD-LSFKLPPGGIVGVIGPNGAGKS 362
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 379 TLIKLLLGQMKPSEGTIERADfnSV---YIDQDYSMINHSLSVIQQ-AESFNWLPLPEHEVKT--ILSRFLFGKETWDKS 452
Cdd:TIGR03719 363 TLFRMITGQEQPDSGTIEIGE--TVklaYVDQSRDALDPNKTVWEEiSGGLDIIKLGKREIPSraYVGRFNFKGSDQQKK 440
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 453 CSVLSGGERMRLLLACLSITGKapDIIILDEPTNNLDLQNIEILTNAIRDYKGTLLVISHDDVFSEEinIETRIL 527
Cdd:TIGR03719 441 VGQLSGGERNRVHLAKTLKSGG--NVLLLDEPTNDLDVETLRALEEALLNFAGCAVVISHDRWFLDR--IATHIL 511
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
1-527 |
1.71e-61 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 210.90 E-value: 1.71e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEiLFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVY--YLPQilEQF--- 75
Cdd:PRK15064 1 MLSTANITMQFGAKP-LFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPNERlgKLRQ--DQFafe 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 76 -----DT-----QSIARALGVQKKLSALREILEgivtEENITVLDdnwdLEEKikqaletWGLLD-FTAdES-------- 136
Cdd:PRK15064 78 eftvlDTvimghTELWEVKQERDRIYALPEMSE----EDGMKVAD----LEVK-------FAEMDgYTA-EAragelllg 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 137 -----------MNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLLN-LLPK 204
Cdd:PRK15064 142 vgipeeqhyglMSEVAPGWKLRVLLAQALFSNPDILLLDEPTNNLDINTIRWLEDVLNERNSTMIIISHDRHFLNsVCTH 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 205 TAELSRKEMMLYGGNYDSYKEQKQIQQNALQNsikntENALKKAKATERETLERQQKLDAKgKKKQekagvakimmntlr 284
Cdd:PRK15064 222 MADLDYGELRVYPGNYDEYMTAATQARERLLA-----DNAKKKAQIAELQSFVSRFSANAS-KAKQ-------------- 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 285 nnaenstAKIRDTHSDKIEglSQELQQLRRGVPLtdqmkLGFDQ-ANLHRgkILIKAEHINHAYQDKNIWKKpLDVVVSS 363
Cdd:PRK15064 282 -------ATSRAKQIDKIK--LEEVKPSSRQNPF-----IRFEQdKKLHR--NALEVENLTKGFDNGPLFKN-LNLLLEA 344
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 364 GERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSV-YIDQDysminHSLSVIQQAESFNWLPL---PEHE---VK 436
Cdd:PRK15064 345 GERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSENANIgYYAQD-----HAYDFENDLTLFDWMSQwrqEGDDeqaVR 419
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 437 TILSRFLFGKETWDKSCSVLSGGERMRLLLACLsITGKaPDIIILDEPTNNLDLQNIEILTNAIRDYKGTLLVISHDDVF 516
Cdd:PRK15064 420 GTLGRLLFSQDDIKKSVKVLSGGEKGRMLFGKL-MMQK-PNVLVMDEPTNHMDMESIESLNMALEKYEGTLIFVSHDREF 497
|
570
....*....|.
gi 639228517 517 SEeiNIETRIL 527
Cdd:PRK15064 498 VS--SLATRII 506
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
12-513 |
2.12e-57 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 200.34 E-value: 2.12e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 12 PDKEILFE-NLNFIvnKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIR-TEG-SVYYLPQilE-QFDTQSIAR---AL 84
Cdd:PRK11819 18 PKKQILKDiSLSFF--PGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARpAPGiKVGYLPQ--EpQLDPEKTVRenvEE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 85 GVQKKLSALREiLEGIVTE--ENITVLD----------------DNWDLEEKIKQALETWGLLDftADESMNRLSGGQKT 146
Cdd:PRK11819 94 GVAEVKAALDR-FNEIYAAyaEPDADFDalaaeqgelqeiidaaDAWDLDSQLEIAMDALRCPP--WDAKVTKLSGGERR 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 147 KVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLL-NLLPKTAELSRKEMMLYGGNYDSYKE 225
Cdd:PRK11819 171 RVALCRLLLEKPDMLLLDEPTNHLDAESVAWLEQFLHDYPGTVVAVTHDRYFLdNVAGWILELDRGRGIPWEGNYSSWLE 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 226 QKQ--IQQNALQNSikntenalKKAKATEREtLE--RQqklDAKGKKKQEKAgvakimmntlRNNAENstakirdthsdk 301
Cdd:PRK11819 251 QKAkrLAQEEKQEA--------ARQKALKRE-LEwvRQ---SPKARQAKSKA----------RLARYE------------ 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 302 iEGLSQELQQlrrgvpltdqmKLGFDQANL----HRGKILIKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGK 377
Cdd:PRK11819 297 -ELLSEEYQK-----------RNETNEIFIppgpRLGDKVIEAENLSKSFGDRLLIDD-LSFSLPPGGIVGIIGPNGAGK 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 378 TTLIKLLLGQMKPSEGTIERADfnSV---YIDQDYSMINHSLSVIQQ-AESFNWLPLPEHEVKT--ILSRFLFGKETWDK 451
Cdd:PRK11819 364 STLFKMITGQEQPDSGTIKIGE--TVklaYVDQSRDALDPNKTVWEEiSGGLDIIKVGNREIPSraYVGRFNFKGGDQQK 441
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639228517 452 SCSVLSGGERMRLLLACLSITGKapDIIILDEPTNNLDLQNIEILTNAIRDYKGTLLVISHD 513
Cdd:PRK11819 442 KVGVLSGGERNRLHLAKTLKQGG--NVLLLDEPTNDLDVETLRALEEALLEFPGCAVVISHD 501
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
17-516 |
3.38e-57 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 201.33 E-value: 3.38e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 17 LFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTE-----------------GSVY------------Y 67
Cdd:PRK11147 18 LLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEqdlivarlqqdpprnveGTVYdfvaegieeqaeY 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 68 LP---QILEQFDTQSIARALgvqKKLSALREILEGivteenitvlDDNWDLEEKIKQALETWGLldfTADESMNRLSGGQ 144
Cdd:PRK11147 98 LKryhDISHLVETDPSEKNL---NELAKLQEQLDH----------HNLWQLENRINEVLAQLGL---DPDAALSSLSGGW 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLL-NLLPKTAELSRKEMMLYGGNYDSY 223
Cdd:PRK11147 162 LRKAALGRALVSNPDVLLLDEPTNHLDIETIEWLEGFLKTFQGSIIFISHDRSFIrNMATRIVDLDRGKLVSYPGNYDQY 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 224 KEQKQ--IQQNALQnsiknteNALKKAKATERETLERQqkldakgkkkqekaGVakimmntlrnnaenstaKIRDTHSdk 301
Cdd:PRK11147 242 LLEKEeaLRVEELQ-------NAEFDRKLAQEEVWIRQ--------------GI-----------------KARRTRN-- 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 302 iEGLSQELQQL------RRGVPLTDQMKLgfDQANlHRGKILIKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGS 375
Cdd:PRK11147 282 -EGRVRALKALrrerseRREVMGTAKMQV--EEAS-RSGKIVFEMENVNYQIDGKQLVKD-FSAQVQRGDKIALIGPNGC 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 376 GKTTLIKLLLGQMKPSEGTI------ERAdfnsvYIDQDYSMINHSLSVI------QQAESFNwlPLPEHeVKTILSRFL 443
Cdd:PRK11147 357 GKTTLLKLMLGQLQADSGRIhcgtklEVA-----YFDQHRAELDPEKTVMdnlaegKQEVMVN--GRPRH-VLGYLQDFL 428
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639228517 444 FGKETWDKSCSVLSGGERMRLLLACLSItgKAPDIIILDEPTNNLDLQNIEILTNAIRDYKGTLLVISHDDVF 516
Cdd:PRK11147 429 FHPKRAMTPVKALSGGERNRLLLARLFL--KPSNLLILDEPTNDLDVETLELLEELLDSYQGTVLLVSHDRQF 499
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-513 |
2.76e-47 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 172.01 E-value: 2.76e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEI-LFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAgdiRTEGSVYYLPQILEQFDTQS 79
Cdd:COG1123 4 LLEVRDLSVRYPGGDVpAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGG---RISGEVLLDGRDLLELSEAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 80 IARALGV--QKKLSAL------REILEGIvteENITVLDDnwDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIA 151
Cdd:COG1123 81 RGRRIGMvfQDPMTQLnpvtvgDQIAEAL---ENLGLSRA--EARARVLELLEAVGLERR-LDRYPHQLSGGQRQRVAIA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 152 GIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHDrtllnlLPKTAELSRKEMMLYGGnydsykeqk 227
Cdd:COG1123 155 MALALDPDLLIADEPTTALDVTTQAEILDLLrelqRERGTTVLLITHD------LGVVAEIADRVVVMDDG--------- 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 228 QIQqnalqnsikntenalkkAKATERETLERQQKLDAkgkkkqekagvakimmntlrnnaenstakirdthsdkieglsq 307
Cdd:COG1123 220 RIV-----------------EDGPPEEILAAPQALAA------------------------------------------- 239
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 308 elqqlrrgVPLTDQMKLGFDQANlHRGKILIKAEHINHAYQDKNiwKKPLDVV--VS----SGERILIIGENGSGKTTLI 381
Cdd:COG1123 240 --------VPRLGAARGRAAPAA-AAAEPLLEVRNLSKRYPVRG--KGGVRAVddVSltlrRGETLGLVGESGSGKSTLA 308
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 382 KLLLGQMKPSEGTI-------------ERADFNSV--YIDQD-YSMINHSLSVIQQ-AES---FNWLPLPEHE--VKTIL 439
Cdd:COG1123 309 RLLLGLLRPTSGSIlfdgkdltklsrrSLRELRRRvqMVFQDpYSSLNPRMTVGDIiAEPlrlHGLLSRAERRerVAELL 388
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 440 SRFLFGKETWDKSCSVLSGGERMRLLLACLSITGkaPDIIILDEPTNNLDL----QNIEILTNAIRDYKGTLLVISHD 513
Cdd:COG1123 389 ERVGLPPDLADRYPHELSGGQRQRVAIARALALE--PKLLILDEPTSALDVsvqaQILNLLRDLQRELGLTYLFISHD 464
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
2-207 |
7.70e-43 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 152.10 E-value: 7.70e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSIA 81
Cdd:COG1122 1 IELENLSFSYPGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDG------KDITKKNLRELR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGV-------QkklsalreilegIVTEeniTVLDD------NWDL-----EEKIKQALETWGLLDFtADESMNRLSGG 143
Cdd:COG1122 75 RKVGLvfqnpddQ------------LFAP---TVEEDvafgpeNLGLpreeiRERVEEALELVGLEHL-ADRPPHELSGG 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639228517 144 QKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN---TNKTLLVVSHDrtlLNLLPKTAE 207
Cdd:COG1122 139 QKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRlnkEGKTVIIVTHD---LDLVAELAD 202
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-211 |
6.67e-42 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 150.24 E-value: 6.67e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVY--------YLPQIl 72
Cdd:COG1121 6 AIELENLTVSYGGRPVL-EDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPrrarrrigYVPQR- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 73 EQFDTQSIAR-----ALGVQKKLSALReilegIVTEENitvlddnwdlEEKIKQALETWGLLDFtADESMNRLSGGQKTK 147
Cdd:COG1121 84 AEVDWDFPITvrdvvLMGRYGRRGLFR-----RPSRAD----------REAVDEALERVGLEDL-ADRPIGELSGGQQQR 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 148 VLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHD-RTLLNLLPKTAELSRK 211
Cdd:COG1121 148 VLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRelrREGKTILVVTHDlGAVREYFDRVLLLNRG 215
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1-226 |
9.32e-42 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 156.76 E-value: 9.32e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEIlFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTeGS---VYYLPQILEQFDt 77
Cdd:COG0488 315 VLELEGLSKSYGDKTL-LDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GEtvkIGYFDQHQEELD- 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 qsiaralgvqkklsalreilegivteENITVLD------DNWDlEEKIKQALETWGlldFTADESMNR---LSGGQKTKV 148
Cdd:COG0488 392 --------------------------PDKTVLDelrdgaPGGT-EQEVRGYLGRFL---FSGDDAFKPvgvLSGGEKARL 441
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 149 LIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLLNLL-PKTAELSRKEMMLYGGNYDSYKEQ 226
Cdd:COG0488 442 ALAKLLLSPPNVLLLDEPTNHLDIETLEALEEALDDFPGTVLLVSHDRYFLDRVaTRILEFEDGGVREYPGGYDDYLEK 520
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
1-201 |
3.83e-41 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 148.65 E-value: 3.83e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSI 80
Cdd:COG1120 1 MLEAENLSVGYGGRPVL-DDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDG------RDLASLSRREL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGV--QKklsalreilegIVTEENITVLD----------DNW-----DLEEKIKQALETWGLLDFtADESMNRLSGG 143
Cdd:COG1120 74 ARRIAYvpQE-----------PPAPFGLTVRElvalgryphlGLFgrpsaEDREAVEEALERTGLEHL-ADRPVDELSGG 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639228517 144 QKTKVLIAGIEIHQPDIILMDEPTNHLD--RQSR--EQLYEFIENTNKTLLVVSHDrtlLNL 201
Cdd:COG1120 142 ERQRVLIARALAQEPPLLLLDEPTSHLDlaHQLEvlELLRRLARERGRTVVMVLHD---LNL 200
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
16-513 |
8.77e-40 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 153.02 E-value: 8.77e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 16 ILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG--SVYYLPQILEQFDTQSIARALGVQKKLSAL 93
Cdd:PRK10636 15 VLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGnwQLAWVNQETPALPQPALEYVIDGDREYRQL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 94 REILEgIVTEEN----ITVLD------DNWDLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIHQPDIILM 163
Cdd:PRK10636 95 EAQLH-DANERNdghaIATIHgkldaiDAWTIRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNLAQALICRSDLLLL 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 164 DEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLLN-LLPKTAELSRKEMMLYGGNYDSYKEQ---KQIQQNALQNSIK 239
Cdd:PRK10636 174 DEPTNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDpIVDKIIHIEQQSLFEYTGNYSSFEVQratRLAQQQAMYESQQ 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 240 NTENALK------KAKATeretlerqqkldaKGKKKQEKAGVAKIMmntlrnnaenstAKIRDTHSDKIEGLSqelqqLR 313
Cdd:PRK10636 254 ERVAHLQsyidrfRAKAT-------------KAKQAQSRIKMLERM------------ELIAPAHVDNPFHFS-----FR 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 314 RGVPLTDQmklgfdqanlhrgkiLIKAEHINHAYQDKNIWKK-PLDVVvsSGERILIIGENGSGKTTLIKLLLGQMKPSE 392
Cdd:PRK10636 304 APESLPNP---------------LLKMEKVSAGYGDRIILDSiKLNLV--PGSRIGLLGRNGAGKSTLIKLLAGELAPVS 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 393 GTIERADFNSV-YIDQdysminHSLSVIQQAESfnwlPL----------PEHEVKTILSRFLFGKETWDKSCSVLSGGER 461
Cdd:PRK10636 367 GEIGLAKGIKLgYFAQ------HQLEFLRADES----PLqhlarlapqeLEQKLRDYLGGFGFQGDKVTEETRRFSGGEK 436
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 639228517 462 MRLLLAClsITGKAPDIIILDEPTNNLDLQNIEILTNAIRDYKGTLLVISHD 513
Cdd:PRK10636 437 ARLVLAL--IVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGALVVVSHD 486
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
4-211 |
1.33e-39 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 143.06 E-value: 1.33e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG--------SVYYLPQILEqF 75
Cdd:cd03235 2 VEDLTVSYGGHPVL-EDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGkplekerkRIGYVPQRRS-I 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 76 DTQSIAR-----ALGVQKKLSALReilegivteeNITVLDdnwdlEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLI 150
Cdd:cd03235 80 DRDFPISvrdvvLMGLYGHKGLFR----------RLSKAD-----KAKVDEALERVGLSEL-ADRQIGELSGGQQQRVLL 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 151 AGIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN---TNKTLLVVSHDR-TLLNLLPKTAELSRK 211
Cdd:cd03235 144 ARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRElrrEGMTILVVTHDLgLVLEYFDRVLLLNRT 208
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
2-200 |
2.57e-39 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 139.89 E-value: 2.57e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKeILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRT--EGSVYYLPQileqfdtqs 79
Cdd:cd03221 1 IELENLSKTYGGK-LLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWgsTVKIGYFEQ--------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 80 iaralgvqkklsalreilegivteenitvlddnwdleekikqaletwglldftadesmnrLSGGQKTKVLIAGIEIHQPD 159
Cdd:cd03221 71 ------------------------------------------------------------LSGGEKMRLALAKLLLENPN 90
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 639228517 160 IILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLLN 200
Cdd:cd03221 91 LLLLDEPTNHLDLESIEALEEALKEYPGTVILVSHDRYFLD 131
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
4-195 |
2.05e-38 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 139.91 E-value: 2.05e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKE-ILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPsagdirTEGSVYYLPQILEQFDTQSIAR 82
Cdd:cd03225 2 LKNLSFSYPDGArPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGP------TSGEVLVDGKDLTKLSLKELRR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 83 ALGV--QK------KLSALREILEGIvteENITVLDDnwDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIE 154
Cdd:cd03225 76 KVGLvfQNpddqffGPTVEEEVAFGL---ENLGLPEE--EIEERVEEALELVGLEGL-RDRSPFTLSGGQKQRVAIAGVL 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 639228517 155 IHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHD 195
Cdd:cd03225 150 AMDPDILLLDEPTAGLDPAGRRELLELLKklkAEGKTIIIVTHD 193
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
3-201 |
1.20e-36 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 133.71 E-value: 1.20e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 3 TLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSIAR 82
Cdd:cd03214 1 EVENLSVGYGGRTVL-DDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDG------KDLASLSPKELAR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 83 ALGVqkklsalreilegivteenitvlddnwdleekIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIIL 162
Cdd:cd03214 74 KIAY--------------------------------VPQALELLGLAHL-ADRPFNELSGGERQRVLLARALAQEPPILL 120
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 639228517 163 MDEPTNHLD--RQSR--EQLYEFIENTNKTLLVVSHDrtlLNL 201
Cdd:cd03214 121 LDEPTSHLDiaHQIEllELLRRLARERGKTVVMVLHD---LNL 160
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
338-513 |
1.49e-36 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 132.19 E-value: 1.49e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKkPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSV-YIDQdysminhsl 416
Cdd:cd03221 1 IELENLSKTYGGKLLLK-DISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTVKIgYFEQ--------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 417 sviqqaesfnwlplpehevktilsrflfgketwdkscsvLSGGERMRLLLACLSITGkaPDIIILDEPTNNLDLQNIEIL 496
Cdd:cd03221 71 ---------------------------------------LSGGEKMRLALAKLLLEN--PNLLLLDEPTNHLDLESIEAL 109
|
170
....*....|....*..
gi 639228517 497 TNAIRDYKGTLLVISHD 513
Cdd:cd03221 110 EEALKEYPGTVILVSHD 126
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
2-201 |
6.46e-36 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 142.28 E-value: 6.46e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHP-DKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSI 80
Cdd:COG2274 474 IELENVSFRYPgDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDG------IDLRQIDPASL 547
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGV--QKklsalREILEGIVtEENITVLDDNWDLEEkIKQALETWGLLDFTAD----------ESMNRLSGGQKTKV 148
Cdd:COG2274 548 RRQIGVvlQD-----VFLFSGTI-RENITLGDPDATDEE-IIEAARLAGLHDFIEAlpmgydtvvgEGGSNLSGGQRQRL 620
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 149 LIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSHDRTLLNL 201
Cdd:COG2274 621 AIARALLRNPRILILDEATSALDAETEAIILENLRRllKGRTVIIIAHRLSTIRL 675
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1-195 |
2.01e-34 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 128.75 E-value: 2.01e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHpDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVyyLPQILEQFDTQ-- 78
Cdd:COG4133 2 MLEAENLSCRR-GERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEP--IRDAREDYRRRla 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 SIARALGVQKKLSALreilegivteENITVLDDNWDL---EEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEI 155
Cdd:COG4133 79 YLGHADGLKPELTVR----------ENLRFWAALYGLradREAIDEALEAVGLAGL-ADLPVRQLSAGQKRRVALARLLL 147
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 639228517 156 HQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHD 195
Cdd:COG4133 148 SPAPLWLLDEPFTALDAAGVALLAELIAahlARGGAVLLTTHQ 190
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
4-195 |
2.04e-32 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 125.24 E-value: 2.04e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKEIL-FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqFDTQSIAR 82
Cdd:TIGR04520 3 VENVSFSYPESEKPaLKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDG-----------LDTLDEEN 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 83 ALGVQKKLsalreileGIVTE--EN----ITVLDD------NW-----DLEEKIKQALETWGLLDFtADESMNRLSGGQK 145
Cdd:TIGR04520 72 LWEIRKKV--------GMVFQnpDNqfvgATVEDDvafgleNLgvpreEMRKRVDEALKLVGMEDF-RDREPHLLSGGQK 142
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:TIGR04520 143 QRVAIAGVLAMRPDIIILDEATSMLDPKGRKEVLETIrklnKEEGITVISITHD 196
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
2-195 |
2.49e-32 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 124.02 E-value: 2.49e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqFDtqsia 81
Cdd:COG1131 1 IEVRGLTKRYGDKTAL-DGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLG-----------ED----- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 ralgVQKKLSALREILeGIVTEE-----NITVLD-----------DNWDLEEKIKQALETWGLLDFtADESMNRLSGGQK 145
Cdd:COG1131 64 ----VARDPAEVRRRI-GYVPQEpalypDLTVREnlrffarlyglPRKEARERIDELLELFGLTDA-ADRKVGTLSGGMK 137
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHD 195
Cdd:COG1131 138 QRLGLALALLHDPELLILDEPTSGLDPEARRELWELLRelaAEGKTVLLSTHY 190
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
2-201 |
1.47e-31 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 121.16 E-value: 1.47e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEIL-FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPsagdirTEGSVYYLPQILEQFDTQSI 80
Cdd:cd03245 3 IEFRNVSFSYPNQEIPaLDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKP------TSGSVLLDGTDIRQLDPADL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALG-VQKKLS----ALReilegivteENITVLDDNWDlEEKIKQALETWGLLDFTAD--ESMNR--------LSGGQK 145
Cdd:cd03245 77 RRNIGyVPQDVTlfygTLR---------DNITLGAPLAD-DERILRAAELAGVTDFVNKhpNGLDLqigergrgLSGGQR 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENT--NKTLLVVSHDRTLLNL 201
Cdd:cd03245 147 QAVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLlgDKTLIIITHRPSLLDL 204
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1-195 |
3.60e-31 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 120.73 E-value: 3.60e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPsagdirTEGSVYYlpqileqFDTQSI 80
Cdd:COG4555 1 MIEVENLSKKYGKVPAL-KDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKP------DSGSILI-------DGEDVR 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKKLSAL---REILEGIVTEENITV---LDDNWD--LEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAG 152
Cdd:COG4555 67 KEPREARRQIGVLpdeRGLYDRLTVRENIRYfaeLYGLFDeeLKKRIEELIELLGLEEF-LDRRVGELSTGMKKKVALAR 145
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 639228517 153 IEIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHD 195
Cdd:COG4555 146 ALVHDPKVLLLDEPTNGLDVMARRLLREILRalkKEGKTVLFSSHI 191
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-209 |
7.85e-31 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 119.38 E-value: 7.85e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFE---NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqfdt 77
Cdd:COG1136 4 LLELRNLTKSYGTGEGEVTalrGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDG-------------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 QSIARaLGvQKKLSALR--EIleGIV-----------TEENIT---VLD--DNWDLEEKIKQALETWGLLDFtADESMNR 139
Cdd:COG1136 70 QDISS-LS-ERELARLRrrHI--GFVfqffnllpeltALENVAlplLLAgvSRKERRERARELLERVGLGDR-LDHRPSQ 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639228517 140 LSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHDRTLLNLLPKTAELS 209
Cdd:COG1136 145 LSGGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRelgtTIVMVTHDPELAARADRVIRLR 218
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
2-200 |
7.97e-31 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 118.77 E-value: 7.97e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVY-------------YL 68
Cdd:COG4619 1 LELEGLSFRVGGKPIL-SPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLsampppewrrqvaYV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 69 PQIleqfdtqsiaralgvqkklSALreiLEGIVtEENI----TVLDDNWDlEEKIKQALETWGLLDFTADESMNRLSGGQ 144
Cdd:COG4619 80 PQE-------------------PAL---WGGTV-RDNLpfpfQLRERKFD-RERALELLERLGLPPDILDKPVERLSGGE 135
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 639228517 145 KTKV-LIAGIeIHQPDIILMDEPTNHLDRQSREQ----LYEFIENTNKTLLVVSHDRTLLN 200
Cdd:COG4619 136 RQRLaLIRAL-LLQPDVLLLDEPTSALDPENTRRveelLREYLAEEGRAVLWVSHDPEQIE 195
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
2-230 |
8.93e-31 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 125.77 E-value: 8.93e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITyQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIR-TEG-SVYYLPQ-ILEQFDtq 78
Cdd:PRK15064 320 LEVENLT-KGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKwSENaNIGYYAQdHAYDFE-- 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 siaralgvqkklsalreilegivteENITVLD--DNWDLEEKIKQALE-TWGLLDFTADE---SMNRLSGGQKTKVLIAG 152
Cdd:PRK15064 397 -------------------------NDLTLFDwmSQWRQEGDDEQAVRgTLGRLLFSQDDikkSVKVLSGGEKGRMLFGK 451
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 153 IEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLLN-LLPKTAELSRKEMMLYGGNYDSYKEQKQIQ 230
Cdd:PRK15064 452 LMMQKPNVLVMDEPTNHMDMESIESLNMALEKYEGTLIFVSHDREFVSsLATRIIEITPDGVVDFSGTYEEYLRSQGIE 530
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
2-195 |
1.16e-30 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 117.11 E-value: 1.16e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqfdtQSIA 81
Cdd:cd03230 1 IEVRNLSKRYGKKTAL-DDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLG--------------KDIK 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RalgvqKKLSALREIleGIVTEENItvLDDNwdleekikqaletwglldFTADESMnRLSGGQKTKVLIAGIEIHQPDII 161
Cdd:cd03230 66 K-----EPEEVKRRI--GYLPEEPS--LYEN------------------LTVRENL-KLSGGMKQRLALAQALLHDPELL 117
|
170 180 190
....*....|....*....|....*....|....*..
gi 639228517 162 LMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHD 195
Cdd:cd03230 118 ILDEPTSGLDPESRREFWELLRelkKEGKTILLSSHI 154
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
2-195 |
1.86e-30 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 124.87 E-value: 1.86e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSIA 81
Cdd:COG4988 337 IELEDVSFSYPGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILING------VDLSDLDPASWR 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGV--QKklSALreiLEGIVtEENITVLDDNWDlEEKIKQALETWGLLDFTAD----------ESMNRLSGGQKTKVL 149
Cdd:COG4988 411 RQIAWvpQN--PYL---FAGTI-RENLRLGRPDAS-DEELEAALEAAGLDEFVAAlpdgldtplgEGGRGLSGGQAQRLA 483
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 150 IAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSHD 195
Cdd:COG4988 484 LARALLRDAPLLLLDEPTAHLDAETEAEILQALRRlaKGRTVILITHR 531
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
2-199 |
2.39e-30 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 124.88 E-value: 2.39e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPD-KEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSI 80
Cdd:COG4987 334 LELEDVSFRYPGaGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGG------VDLRDLDEDDL 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVqkklsalreilegiVTE----------ENITVLDDNWDlEEKIKQALETWGLLDFTAD----------ESMNRL 140
Cdd:COG4987 408 RRRIAV--------------VPQrphlfdttlrENLRLARPDAT-DEELWAALERVGLGDWLAAlpdgldtwlgEGGRRL 472
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 639228517 141 SGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENT--NKTLLVVSHDRTLL 199
Cdd:COG4987 473 SGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEAlaGRTVLLITHRLAGL 533
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
2-195 |
6.10e-30 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 118.58 E-value: 6.10e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEIL-FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileqfdtqSI 80
Cdd:PRK13635 6 IRVEHISFRYPDAATYaLKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVL------------SE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKKLsalreileGIVTE--EN----ITVLDD-NWDLE----------EKIKQALETWGLLDFtADESMNRLSGG 143
Cdd:PRK13635 74 ETVWDVRRQV--------GMVFQnpDNqfvgATVQDDvAFGLEnigvpreemvERVDQALRQVGMEDF-LNREPHRLSGG 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 144 QKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:PRK13635 145 QKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVrqlkEQKGITVLSITHD 200
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
2-201 |
2.94e-29 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 114.89 E-value: 2.94e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNI--TYQHPDKEI-LFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqFDTQ 78
Cdd:cd03255 1 IELKNLskTYGGGGEKVqALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDG-----------TDIS 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 SIARalgvqKKLSALR--EIleGIVTEE-----NITVLD-----------DNWDLEEKIKQALETWGLldftaDESMNR- 139
Cdd:cd03255 70 KLSE-----KELAAFRrrHI--GFVFQSfnllpDLTALEnvelplllagvPKKERRERAEELLERVGL-----GDRLNHy 137
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 140 ---LSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQ----LYEFIENTNKTLLVVSHDRTLLNL 201
Cdd:cd03255 138 pseLSGGQQQRVAIARALANDPKIILADEPTGNLDSETGKEvmelLRELNKEAGTTIVVVTHDPELAEY 206
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
129-514 |
3.66e-29 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 121.89 E-value: 3.66e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 129 LDFTAD---ESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLLN-LLPK 204
Cdd:PLN03073 331 LSFTPEmqvKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYLLKWPKTFIVVSHAREFLNtVVTD 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 205 TAELSRKEMMLYGGNYDSYKEQKQIQqnalqnsIKNTENALKkakATERETLERQQKLDakgkkkqekagvaKIMMNTLR 284
Cdd:PLN03073 411 ILHLHGQKLVTYKGDYDTFERTREEQ-------LKNQQKAFE---SNERSRSHMQAFID-------------KFRYNAKR 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 285 NNAENSTAKIRDT--HSDKIeglsqelqqlrrgvpLTD-QMKLGFDQANLHRGKILIKAEHINHAYQDKNIWKKPLDVVV 361
Cdd:PLN03073 468 ASLVQSRIKALDRlgHVDAV---------------VNDpDYKFEFPTPDDRPGPPIISFSDASFGYPGGPLLFKNLNFGI 532
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 362 SSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIER------ADFNSVYIDQ-DYSminhSLSVIQQAESFnwlP-LPEH 433
Cdd:PLN03073 533 DLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRsakvrmAVFSQHHVDGlDLS----SNPLLYMMRCF---PgVPEQ 605
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 434 EVKTILSRFLFGKETWDKSCSVLSGGERMRLLLAclSITGKAPDIIILDEPTNNLDLQNIEILTNAIRDYKGTLLVISHD 513
Cdd:PLN03073 606 KLRAHLGSFGVTGNLALQPMYTLSGGQKSRVAFA--KITFKKPHILLLDEPSNHLDLDAVEALIQGLVLFQGGVLMVSHD 683
|
.
gi 639228517 514 D 514
Cdd:PLN03073 684 E 684
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
4-201 |
7.29e-29 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 121.13 E-value: 7.29e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKEIL-FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPsagdirTEGSVYylpqiLEQFDTQSIAR 82
Cdd:TIGR03375 466 FRNVSFAYPGQETPaLDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQP------TEGSVL-----LDGVDIRQIDP 534
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 83 AlgvqkklsALREILeGIVTE----------ENITV----LDDnwdleEKIKQALETWGLLDFTAD----------ESMN 138
Cdd:TIGR03375 535 A--------DLRRNI-GYVPQdprlfygtlrDNIALgapyADD-----EEILRAAELAGVTEFVRRhpdgldmqigERGR 600
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 139 RLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENT--NKTLLVVSHDRTLLNL 201
Cdd:TIGR03375 601 SLSGGQRQAVALARALLRDPPILLLDEPTSAMDNRSEERFKDRLKRWlaGKTLVLVTHRTSLLDL 665
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1-204 |
1.88e-28 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 112.84 E-value: 1.88e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqFDTQSI 80
Cdd:COG2884 1 MIRFENVSKRYPGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNG-----------QDLSRL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARalgvqKKLSALR-EIleGIVTEE-----NITVLD-----------DNWDLEEKIKQALETWGLLDFtADESMNRLSGG 143
Cdd:COG2884 70 KR-----REIPYLRrRI--GVVFQDfrllpDRTVYEnvalplrvtgkSRKEIRRRVREVLDLVGLSDK-AKALPHELSGG 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 144 QKTKVLIA-GIeIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK---TLLVVSHDRTLLNLLPK 204
Cdd:COG2884 142 EQQRVAIArAL-VNRPELLLADEPTGNLDPETSWEIMELLEEINRrgtTVLIATHDLELVDRMPK 205
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1-194 |
2.02e-28 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 113.26 E-value: 2.02e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDirtegSVYYLPQILEQFDTQSI 80
Cdd:COG1119 3 LLELRNVTVRRGGKTIL-DDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGN-----DVRLFGERRGGEDVWEL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGV---------QKKLSALREILEG----IVTEENITVLDdnwdlEEKIKQALETWGLLDFtADESMNRLSGGQKTK 147
Cdd:COG1119 77 RKRIGLvspalqlrfPRDETVLDVVLSGffdsIGLYREPTDEQ-----RERARELLELLGLAHL-ADRPFGTLSQGEQRR 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 148 VLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE----NTNKTLLVVSH 194
Cdd:COG1119 151 VLIARALVKDPELLILDEPTAGLDLGARELLLALLDklaaEGAPTLVLVTH 201
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
2-199 |
2.15e-28 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 110.94 E-value: 2.15e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKE-ILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRtegsvyylpqileqFDTQSI 80
Cdd:cd03228 1 IEFKNVSFSYPGRPkPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEIL--------------IDGVDL 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARAlgvqkKLSALREILeGIVTEENItvlddnwdleekikqaletwgLLDFT-ADesmNRLSGGQKTKVLIAGIEIHQPD 159
Cdd:cd03228 67 RDL-----DLESLRKNI-AYVPQDPF---------------------LFSGTiRE---NILSGGQRQRIAIARALLRDPP 116
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 639228517 160 IILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSHDRTLL 199
Cdd:cd03228 117 ILILDEATSALDPETEALILEALRAlaKGKTVIVIAHRLSTI 158
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
3-203 |
2.59e-28 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 110.41 E-value: 2.59e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 3 TLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRtegsvyylpqileqFDTQSIAr 82
Cdd:cd00267 1 EIENLSFRYGGRTAL-DNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEIL--------------IDGKDIA- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 83 algvQKKLSALREILeGIVTEenitvlddnwdleekikqaletwglldftadesmnrLSGGQKTKVLIAGIEIHQPDIIL 162
Cdd:cd00267 65 ----KLPLEELRRRI-GYVPQ------------------------------------LSGGQRQRVALARALLLNPDLLL 103
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 639228517 163 MDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHDRTLLNLLP 203
Cdd:cd00267 104 LDEPTSGLDPASRERLLELLRelaEEGRTVIIVTHDPELAELAA 147
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
337-513 |
4.52e-28 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 112.10 E-value: 4.52e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKkPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERAdfnsvyiDQDYSMINHSL 416
Cdd:COG1121 6 AIELENLTVSYGGRPVLE-DVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLF-------GKPPRRARRRI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 417 SVIQQAESFNW-LPLPEHEV-------KTILSRFLfGKETW----------------DKSCSVLSGGERMRLLLA-CLsi 471
Cdd:COG1121 78 GYVPQRAEVDWdFPITVRDVvlmgrygRRGLFRRP-SRADReavdealervgledlaDRPIGELSGGQQQRVLLArAL-- 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 639228517 472 tgkA--PDIIILDEPTNNLDLQNIEILTNAIRDYKG---TLLVISHD 513
Cdd:COG1121 155 ---AqdPDLLLLDEPFAGVDAATEEALYELLRELRRegkTILVVTHD 198
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
3-218 |
6.71e-28 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 110.81 E-value: 6.71e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 3 TLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG----------SVYYLPQIL 72
Cdd:cd03226 1 RIENISFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGkpikakerrkSIGYVMQDV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 73 E-QFDTQSIARalgvqkklsalrEILEGivteenitvLDDNWDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIA 151
Cdd:cd03226 81 DyQLFTDSVRE------------ELLLG---------LKELDAGNEQAETVLKDLDLYAL-KERHPLSLSGGQKQRLAIA 138
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 152 GIEIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHDRTLLnllpktAELSRKEMMLYGG 218
Cdd:cd03226 139 AALLSGKDLLIFDEPTSGLDYKNMERVGELIRelaAQGKAVIVITHDYEFL------AKVCDRVLLLANG 202
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
19-195 |
6.82e-28 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 112.54 E-value: 6.82e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIrtegsvyylpqileQFDTQSIARalGVQKKLSALREILe 98
Cdd:TIGR04521 22 DDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTV--------------TIDGRDITA--KKKKKLKDLRKKV- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 99 GIVT--------EEniTVLDD------NWDL-----EEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIHQPD 159
Cdd:TIGR04521 85 GLVFqfpehqlfEE--TVYKDiafgpkNLGLseeeaEERVKEALELVGLDEEYLERSPFELSGGQMRRVAIAGVLAMEPE 162
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 639228517 160 IILMDEPTNHLDRQSREQLYEFIEN----TNKTLLVVSHD 195
Cdd:TIGR04521 163 VLILDEPTAGLDPKGRKEILDLFKRlhkeKGLTVILVTHS 202
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
338-513 |
5.00e-27 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 108.96 E-value: 5.00e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTieradfnsVYIDqDYSMINHSLS 417
Cdd:COG1122 1 IELENLSFSYPGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGE--------VLVD-GKDITKKNLR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 418 --------VIQQAE------------SF---NwLPLPEHEVKTILSRFL--FGKETW-DKSCSVLSGGERMRLLLACLSI 471
Cdd:COG1122 72 elrrkvglVFQNPDdqlfaptveedvAFgpeN-LGLPREEIRERVEEALelVGLEHLaDRPPHELSGGQKQRVAIAGVLA 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 639228517 472 TGkaPDIIILDEPTNNLDLQNIEILTNAIRDYKG---TLLVISHD 513
Cdd:COG1122 151 ME--PEVLVLDEPTAGLDPRGRRELLELLKRLNKegkTVIIVTHD 193
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
2-195 |
5.90e-27 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 108.33 E-value: 5.90e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNIT--YQHPDKEIL-FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqilEQFDTQ 78
Cdd:cd03293 1 LEVRNVSktYGGGGGAVTaLEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDG---------EPVTGP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 SIARALGVQKklSAL---REILEGIVTEENITVLDDNwDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEI 155
Cdd:cd03293 72 GPDRGYVFQQ--DALlpwLTVLDNVALGLELQGVPKA-EARERAEELLELVGLSGF-ENAYPHQLSGGMRQRVALARALA 147
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 639228517 156 HQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:cd03293 148 VDPDVLLLDEPFSALDALTREQLQEELldiwRETGKTVLLVTHD 191
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
2-205 |
7.89e-27 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 113.92 E-value: 7.89e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSIA 81
Cdd:TIGR02857 322 LEFSGVSVAYPGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNG------VPLADADADSWR 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGVqkkLSALREILEGIVTeENITvLDDNWDLEEKIKQALETWGLLDFTAD----------ESMNRLSGGQKTKVLIA 151
Cdd:TIGR02857 396 DQIAW---VPQHPFLFAGTIA-ENIR-LARPDASDAEIREALERAGLDEFVAAlpqgldtpigEGGAGLSGGQAQRLALA 470
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 152 GIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSHDRTLLNLLPKT 205
Cdd:TIGR02857 471 RAFLRDAPLLLLDEPTAHLDAETEAEVLEALRAlaQGRTVLLVTHRLALAALADRI 526
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
17-195 |
8.07e-27 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 107.32 E-value: 8.07e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 17 LFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG--SVYYLPQILEQFDTQSI----ARALGVQKKL 90
Cdd:NF040873 7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGgaRVAYVPQRSEVPDSLPLtvrdLVAMGRWARR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 91 SALREIlegivTEENITVLDDnwdleekikqALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHL 170
Cdd:NF040873 87 GLWRRL-----TRDDRAAVDD----------ALERVGLADL-AGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGL 150
|
170 180
....*....|....*....|....*...
gi 639228517 171 DRQSREQLYEFIE---NTNKTLLVVSHD 195
Cdd:NF040873 151 DAESRERIIALLAeehARGATVVVVTHD 178
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
339-513 |
1.02e-26 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 107.62 E-value: 1.02e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 339 KAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERAdfnsvyiDQDYSMINHSLSV 418
Cdd:cd03235 1 EVEDLTVSYGGHPVLED-VSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVF-------GKPLEKERKRIGY 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 419 IQQAESFNW-LPLPEHEV-------KTILSRFLfGKETW----------------DKSCSVLSGGERMRLLLA-CLSITg 473
Cdd:cd03235 73 VPQRRSIDRdFPISVRDVvlmglygHKGLFRRL-SKADKakvdealervglselaDRQIGELSGGQQQRVLLArALVQD- 150
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 639228517 474 kaPDIIILDEPTNNLDLQNIEILTNAIRDYKG---TLLVISHD 513
Cdd:cd03235 151 --PDLLLLDEPFAGVDPKTQEDIYELLRELRRegmTILVVTHD 191
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
337-523 |
1.79e-26 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 106.79 E-value: 1.79e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKkPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI---------ERADFNS--VYI 405
Cdd:COG4133 2 MLEAENLSCRRGERLLFS-GLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVlwngepirdAREDYRRrlAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 406 DqDYSMINHSLSVIQQAE---SFNWLPLPEHEVKTILSRF-LFGKEtwDKSCSVLSGGERMRLLLACLsITGKAPdIIIL 481
Cdd:COG4133 81 G-HADGLKPELTVRENLRfwaALYGLRADREAIDEALEAVgLAGLA--DLPVRQLSAGQKRRVALARL-LLSPAP-LWLL 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 482 DEPTNNLDLQNIEILTNAIRDYK---GTLLVISHDDV---FSEEINIE 523
Cdd:COG4133 156 DEPFTALDAAGVALLAELIAAHLargGAVLLTTHQPLelaAARVLDLG 203
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
341-513 |
4.49e-26 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 105.63 E-value: 4.49e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 341 EHINHAYQDKNIWK-KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNsVYIDQDYSMINHSLSVI 419
Cdd:cd03225 3 KNLSFSYPDGARPAlDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKD-LTKLSLKELRRKVGLVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 420 QQAES------------F---NwLPLPEHEVKTILSRFL--FG-KETWDKSCSVLSGGERMRLLLACLSITGkaPDIIIL 481
Cdd:cd03225 82 QNPDDqffgptveeevaFgleN-LGLPEEEIEERVEEALelVGlEGLRDRSPFTLSGGQKQRVAIAGVLAMD--PDILLL 158
|
170 180 190
....*....|....*....|....*....|....*
gi 639228517 482 DEPTNNLDLQNIEILTNAIRDYKG---TLLVISHD 513
Cdd:cd03225 159 DEPTAGLDPAGRRELLELLKKLKAegkTIIIVTHD 193
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
339-528 |
3.60e-25 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 101.55 E-value: 3.60e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 339 KAEHINHAYQDKNIwKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNsvyidqdysminhslsv 418
Cdd:cd00267 1 EIENLSFRYGGRTA-LDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKD----------------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 419 iqqaesfnWLPLPEHEVKTILSrFLFGketwdkscsvLSGGERMRLLLAClsITGKAPDIIILDEPTNNLDLQNIEILTN 498
Cdd:cd00267 63 --------IAKLPLEELRRRIG-YVPQ----------LSGGQRQRVALAR--ALLLNPDLLLLDEPTSGLDPASRERLLE 121
|
170 180 190
....*....|....*....|....*....|...
gi 639228517 499 AIRDYKG---TLLVISHDdvFSEEINIETRILL 528
Cdd:cd00267 122 LLRELAEegrTVIIVTHD--PELAELAADRVIV 152
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-195 |
4.90e-25 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 104.02 E-value: 4.90e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNI--TYQHPDKEIL-FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqfdt 77
Cdd:COG1116 7 ALELRGVskRFPTGGGGVTaLDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDG-------------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 QSIARalgvqkklsALREIleGIV-----------TEENITV-LDDNW----DLEEKIKQALETWGLLDFtadesMNR-- 139
Cdd:COG1116 73 KPVTG---------PGPDR--GVVfqepallpwltVLDNVALgLELRGvpkaERRERARELLELVGLAGF-----EDAyp 136
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639228517 140 --LSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:COG1116 137 hqLSGGMRQRVAIARALANDPEVLLMDEPFGALDALTRERLQDELlrlwQETGKTVLFVTHD 198
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
2-195 |
9.65e-25 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 102.76 E-value: 9.65e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSIA 81
Cdd:cd03295 1 IEFENVTKRYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDG------EDIREQDPVELR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGVqkklsALREI--LEGIVTEENITVLD--DNWDLEEKIKQALETWGLLDFTADESMNR----LSGGQKTKVLIAGI 153
Cdd:cd03295 75 RKIGY-----VIQQIglFPHMTVEENIALVPklLKWPKEKIRERADELLALVGLDPAEFADRypheLSGGQQQRVGVARA 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 639228517 154 EIHQPDIILMDEPTNHLDRQSREQLY-EFI---ENTNKTLLVVSHD 195
Cdd:cd03295 150 LAADPPLLLMDEPFGALDPITRDQLQeEFKrlqQELGKTIVFVTHD 195
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
338-513 |
1.07e-24 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 100.55 E-value: 1.07e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERadFNSVYIDQDYSMINHSLS 417
Cdd:cd03230 1 IEVRNLSKRYGKKTALDD-ISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKV--LGKDIKKEPEEVKRRIGY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 418 VIQQAESFNWLplpehEVKTILSrflfgketwdkscsvLSGGERMRLLLAClSITGKaPDIIILDEPTNNLDLQNIEILT 497
Cdd:cd03230 78 LPEEPSLYENL-----TVRENLK---------------LSGGMKQRLALAQ-ALLHD-PELLILDEPTSGLDPESRREFW 135
|
170
....*....|....*....
gi 639228517 498 NAIRDYK---GTLLVISHD 513
Cdd:cd03230 136 ELLRELKkegKTILLSSHI 154
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
1-210 |
1.10e-24 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 107.59 E-value: 1.10e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIR--TEGSVYYLPQileqfdtq 78
Cdd:COG4178 362 ALALEDLTLRTPDGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIArpAGARVLFLPQ-------- 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 siaRA---LGvqkklsALREILEGIVTEENITvlddnwdlEEKIKQALETWGL------LDFTADESmNRLSGGQKTKVL 149
Cdd:COG4178 434 ---RPylpLG------TLREALLYPATAEAFS--------DAELREALEAVGLghlaerLDEEADWD-QVLSLGEQQRLA 495
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639228517 150 IAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENT--NKTLLVVSHDRTLLNLLPKTAELSR 210
Cdd:COG4178 496 FARLLLHKPDWLFLDEATSALDEENEAALYQLLREElpGTTVISVGHRSTLAAFHDRVLELTG 558
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
18-168 |
1.57e-24 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 99.26 E-value: 1.57e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 18 FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVyyLPQILEQFDTQSIAR---ALGVQKKLSALR 94
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQD--LTDDERKSLRKEIGYvfqDPQLFPRLTVRE 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639228517 95 EILEGIVTEENITVLDDNWdleekIKQALETWGLLDF---TADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTN 168
Cdd:pfam00005 79 NLRLGLLLKGLSKREKDAR-----AEEALEKLGLGDLadrPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
2-197 |
1.78e-24 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 101.06 E-value: 1.78e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRtegsvyylpqileqFDTQSIA 81
Cdd:cd03259 1 LELKGLSKTYGSVRAL-DDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEIL--------------IDGRDVT 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RaLGVQKklsalREIleGIVTEENI-----TVLD-----------DNWDLEEKIKQALETWGLLDFtADESMNRLSGGQK 145
Cdd:cd03259 66 G-VPPER-----RNI--GMVFQDYAlfphlTVAEniafglklrgvPKAEIRARVRELLELVGLEGL-LNRYPHELSGGQQ 136
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLY----EFIENTNKTLLVVSHDRT 197
Cdd:cd03259 137 QRVALARALAREPSLLLLDEPLSALDAKLREELReelkELQRELGITTIYVTHDQE 192
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
1-195 |
2.09e-24 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 102.06 E-value: 2.09e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRtegsvyylpqileqFDTQSI 80
Cdd:COG3638 2 MLELRNLSKRYPGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEIL--------------VDGQDV 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGvqKKLSALR-EIleGIVTE-----ENITVLDdN------------------WDLEEKIK--QALETWGLLDFtAD 134
Cdd:COG3638 68 TALRG--RALRRLRrRI--GMIFQqfnlvPRLSVLT-NvlagrlgrtstwrsllglFPPEDRERalEALERVGLADK-AY 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 135 ESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQ----LYEFIENTNKTLLVVSHD 195
Cdd:COG3638 142 QRADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQvmdlLRRIAREDGITVVVNLHQ 206
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
1-195 |
3.33e-24 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 101.70 E-value: 3.33e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqiLEQFDTQSI 80
Cdd:COG4604 1 MIEIKNVSKRYGGKVVL-DDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDG--------LDVATTPSR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARAlgvqKKLSALReilegivtEEN-----ITVLD-----------------DnwdlEEKIKQALETWGLLDFtADESMN 138
Cdd:COG4604 72 ELA----KRLAILR--------QENhinsrLTVRElvafgrfpyskgrltaeD----REIIDEAIAYLDLEDL-ADRYLD 134
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 639228517 139 RLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLD-RQSRE---QLYEFIENTNKTLLVVSHD 195
Cdd:COG4604 135 ELSGGQRQRAFIAMVLAQDTDYVLLDEPLNNLDmKHSVQmmkLLRRLADELGKTVVIVLHD 195
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
338-513 |
1.02e-23 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 99.75 E-value: 1.02e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKkPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE------RADFNSV-----YID 406
Cdd:COG1131 1 IEVRGLTKRYGDKTALD-GVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRvlgedvARDPAEVrrrigYVP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 407 QDYSMINHsLSVIQQAESFNWL-PLPEHEVKTILSRFL--FG-KETWDKSCSVLSGGERMRLLLAClSITGKaPDIIILD 482
Cdd:COG1131 80 QEPALYPD-LTVRENLRFFARLyGLPRKEARERIDELLelFGlTDAADRKVGTLSGGMKQRLGLAL-ALLHD-PELLILD 156
|
170 180 190
....*....|....*....|....*....|....
gi 639228517 483 EPTNNLDLQNIEILTNAIRDYKG---TLLVISHD 513
Cdd:COG1131 157 EPTSGLDPEARRELWELLRELAAegkTVLLSTHY 190
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
2-195 |
1.57e-23 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 103.98 E-value: 1.57e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyYLPQILEQFDTQSIA 81
Cdd:TIGR02868 335 LELRDLSAGYPGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDG---VPVSSLDQDEVRRRV 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGVQKKL--SALREILegIVTEENITvlddnwdlEEKIKQALETWGLLDFTAD----------ESMNRLSGGQKTKVL 149
Cdd:TIGR02868 412 SVCAQDAHLfdTTVRENL--RLARPDAT--------DEELWAALERVGLADWLRAlpdgldtvlgEGGARLSGGERQRLA 481
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 150 IAGIEIHQPDIILMDEPTNHLDRQSREQLYE--FIENTNKTLLVVSHD 195
Cdd:TIGR02868 482 LARALLADAPILLLDEPTEHLDAETADELLEdlLAALSGRTVVLITHH 529
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
1-195 |
2.24e-23 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 99.68 E-value: 2.24e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKE-ILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileQFDTQS 79
Cdd:PRK13632 7 MIKVENVSFSYPNSEnNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITI-------SKENLK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 80 IARalgvqKKLsalreileGIVTEE------NITVLDD-NWDLEEK----------IKQALETWGLLDFTADESMNrLSG 142
Cdd:PRK13632 80 EIR-----KKI--------GIIFQNpdnqfiGATVEDDiAFGLENKkvppkkmkdiIDDLAKKVGMEDYLDKEPQN-LSG 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 639228517 143 GQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:PRK13632 146 GQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMvdlrKTRKKTLISITHD 202
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-195 |
2.27e-23 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 99.11 E-value: 2.27e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNIT----YQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFD 76
Cdd:COG1124 1 MLEVRNLSvsygQGGRRVPVL-KDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDG------RPVTRRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 77 TQSIARALGV--QKKLSAL--REILEGIVTEE-NITVLDDNwdlEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIA 151
Cdd:COG1124 74 RKAFRRRVQMvfQDPYASLhpRHTVDRILAEPlRIHGLPDR---EERIAELLEQVGLPPSFLDRYPHQLSGGQRQRVAIA 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 152 GIEIHQPDIILMDEPTNHLDRQSREQ----LYEFIENTNKTLLVVSHD 195
Cdd:COG1124 151 RALILEPELLLLDEPTSALDVSVQAEilnlLKDLREERGLTYLFVSHD 198
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
337-513 |
2.41e-23 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 98.96 E-value: 2.41e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKkPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTieradfnsVYID-QDYsminHS 415
Cdd:COG1120 1 MLEAENLSVGYGGRPVLD-DVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGE--------VLLDgRDL----AS 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 416 LSVIQQAESFNWLPlPEHE------VKTI--LSRF----LFGKET-------------------WDKSCSVLSGGERMRL 464
Cdd:COG1120 68 LSRRELARRIAYVP-QEPPapfgltVRELvaLGRYphlgLFGRPSaedreaveealertglehlADRPVDELSGGERQRV 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 465 LLAclsitgKA----PDIIILDEPTNNLDLQN-IEILtNAIRDYKG----TLLVISHD 513
Cdd:COG1120 147 LIA------RAlaqePPLLLLDEPTSHLDLAHqLEVL-ELLRRLARergrTVVMVLHD 197
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
339-513 |
3.06e-23 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 96.74 E-value: 3.06e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 339 KAEHINHAYQDKNIWKkPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeradfnsvYID-QDYSminhSLS 417
Cdd:cd03214 1 EVENLSVGYGGRTVLD-DLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEI--------LLDgKDLA----SLS 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 418 VIQQAESFNWLPlpehevkTILSRF-LFGKEtwDKSCSVLSGGERMRLLLA-CLsitGKAPDIIILDEPTNNLDLQN-IE 494
Cdd:cd03214 68 PKELARKIAYVP-------QALELLgLAHLA--DRPFNELSGGERQRVLLArAL---AQEPPILLLDEPTSHLDIAHqIE 135
|
170 180
....*....|....*....|...
gi 639228517 495 ILtNAIRDYKG----TLLVISHD 513
Cdd:cd03214 136 LL-ELLRRLARergkTVVMVLHD 157
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
337-513 |
3.15e-23 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 98.39 E-value: 3.15e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKkPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQDY----SMI 412
Cdd:COG4555 1 MIEVENLSKKYGKVPALK-DVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREArrqiGVL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 413 NHS------LSVIQQAESFNWL-PLPEHEVKT----ILSRFLFGKETwDKSCSVLSGGERMRLLLACLSITgkAPDIIIL 481
Cdd:COG4555 80 PDErglydrLTVRENIRYFAELyGLFDEELKKrieeLIELLGLEEFL-DRRVGELSTGMKKKVALARALVH--DPKVLLL 156
|
170 180 190
....*....|....*....|....*....|....*
gi 639228517 482 DEPTNNLDLQNIEILTNAIRDYKG---TLLVISHD 513
Cdd:COG4555 157 DEPTNGLDVMARRLLREILRALKKegkTVLFSSHI 191
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
1-200 |
3.79e-23 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 103.40 E-value: 3.79e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGdirtegSVYYLPQILEQFDTQSI 80
Cdd:PLN03073 508 IISFSDASFGYPGGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSG------TVFRSAKVRMAVFSQHH 581
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKK-LSALREILEGIvteenitvlddnwdLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIHQPD 159
Cdd:PLN03073 582 VDGLDLSSNpLLYMMRCFPGV--------------PEQKLRAHLGSFGVTGNLALQPMYTLSGGQKSRVAFAKITFKKPH 647
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 639228517 160 IILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLLN 200
Cdd:PLN03073 648 ILLLDEPSNHLDLDAVEALIQGLVLFQGGVLMVSHDEHLIS 688
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
2-194 |
4.40e-23 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 102.94 E-value: 4.40e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRtegsvyylpqileqFDTQSIA 81
Cdd:COG1132 340 IEFENVSFSYPGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRIL--------------IDGVDIR 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RAlgvqkKLSALREILeGIVT----------EENITVLDDNWDLEEkIKQALETWGLLDFTAD-----ESM-----NRLS 141
Cdd:COG1132 406 DL-----TLESLRRQI-GVVPqdtflfsgtiRENIRYGRPDATDEE-VEEAAKAAQAHEFIEAlpdgyDTVvgergVNLS 478
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 142 GGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSH 194
Cdd:COG1132 479 GGQRQRIAIARALLKDPPILILDEATSALDTETEALIQEALERlmKGRTTIVIAH 533
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
2-213 |
5.34e-23 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 95.75 E-value: 5.34e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPD-KEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDtqsi 80
Cdd:cd03246 1 LEVENVSFRYPGaEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDG------ADISQWD---- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 aralgvqkkLSALREILeGIVTEenitvlDDNwdleekikqaletwgLLDFTADEsmNRLSGGQKTKVLIAGIEIHQPDI 160
Cdd:cd03246 71 ---------PNELGDHV-GYLPQ------DDE---------------LFSGSIAE--NILSGGQRQRLGLARALYGNPRI 117
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 161 ILMDEPTNHLDRQSREQLYEFIENTNK---TLLVVSHDRTLLNLLPKTAELSRKEM 213
Cdd:cd03246 118 LVLDEPNSHLDVEGERALNQAIAALKAagaTRIVIAHRPETLASADRILVLEDGRV 173
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
1-207 |
6.13e-23 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 98.61 E-value: 6.13e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileQFDTQSI 80
Cdd:PRK13639 1 ILETRDLKYSYPDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPI-------KYDKKSL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 araLGVQKKLsalreileGIV---TEENI---TVLDD-----------NWDLEEKIKQALETWGLLDFtADESMNRLSGG 143
Cdd:PRK13639 74 ---LEVRKTV--------GIVfqnPDDQLfapTVEEDvafgplnlglsKEEVEKRVKEALKAVGMEGF-ENKPPHHLSGG 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639228517 144 QKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK---TLLVVSHDrtlLNLLPKTAE 207
Cdd:PRK13639 142 QKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKegiTIIISTHD---VDLVPVYAD 205
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
2-195 |
6.23e-23 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 97.64 E-value: 6.23e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG------SVYYLPQILEQF 75
Cdd:cd03256 1 IEVENLSKTYPNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGtdinklKGKALRQLRRQI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 76 DTqsIARALGVQKKLSALREILEGIVTEEN-ITVLDDNWDLEEKIK--QALETWGLLDFT---ADEsmnrLSGGQKTKVL 149
Cdd:cd03256 81 GM--IFQQFNLIERLSVLENVLSGRLGRRStWRSLFGLFPKEEKQRalAALERVGLLDKAyqrADQ----LSGGQQQRVA 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 639228517 150 IAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:cd03256 155 IARALMQQPKLILADEPVASLDPASSRQVMDLLkrinREEGITVIVSLHQ 204
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1-195 |
1.10e-22 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 96.42 E-value: 1.10e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILF---ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPsagdirTEGSVYYLPQILEQFDT 77
Cdd:cd03257 1 LLEVKNLSVSFPTGGGSVkalDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKP------TSGSIIFDGKDLLKLSR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 Q---SIARALGV--QKKLSAL--REILEGIVTE--ENITVLDDNWDLEEKIKQALETWGLldftADESMNR----LSGGQ 144
Cdd:cd03257 75 RlrkIRRKEIQMvfQDPMSSLnpRMTIGEQIAEplRIHGKLSKKEARKEAVLLLLVGVGL----PEEVLNRypheLSGGQ 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQ----LYEFIENTNKTLLVVSHD 195
Cdd:cd03257 151 RQRVAIARALALNPKLLIADEPTSALDVSVQAQildlLKKLQEELGLTLLFITHD 205
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
13-180 |
1.51e-22 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 95.64 E-value: 1.51e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 13 DKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRtegsvyyLPQILEQFDTQSIARAL-------G 85
Cdd:cd03231 11 DGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVL-------LNGGPLDFQRDSIARGLlylghapG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 86 VQKKLSALreilegivteENITVL-DDNWDleEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIILMD 164
Cdd:cd03231 84 IKTTLSVL----------ENLRFWhADHSD--EQVEEALARVGLNGF-EDRPVAQLSAGQQRRVALARLLLSGRPLWILD 150
|
170
....*....|....*.
gi 639228517 165 EPTNHLDRQSREQLYE 180
Cdd:cd03231 151 EPTTALDKAGVARFAE 166
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
355-486 |
1.52e-22 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 93.87 E-value: 1.52e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 355 KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERaDFNSVYiDQDYSMINHSLSVI-QQAESFNWLPLPEH 433
Cdd:pfam00005 2 KNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILL-DGQDLT-DDERKSLRKEIGYVfQDPQLFPRLTVREN 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639228517 434 -----------------EVKTILSRF---LFGKETWDKSCSVLSGGERMRLLLACLSITGkaPDIIILDEPTN 486
Cdd:pfam00005 80 lrlglllkglskrekdaRAEEALEKLglgDLADRPVGERPGTLSGGQRQRVAIARALLTK--PKLLLLDEPTA 150
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
2-195 |
2.06e-22 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 96.67 E-value: 2.06e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTeGSVYyLPQILEqfDTQSI- 80
Cdd:PRK11247 13 LLLNAVSKRYGERTVL-NQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLA-GTAP-LAEARE--DTRLMf 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 --ARALGVQKKLsalreilegivteENITV-LDDNWdlEEKIKQALETWGLLDfTADESMNRLSGGQKTKVLIAGIEIHQ 157
Cdd:PRK11247 88 qdARLLPWKKVI-------------DNVGLgLKGQW--RDAALQALAAVGLAD-RANEWPAALSGGQKQRVALARALIHR 151
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 639228517 158 PDIILMDEPTNHLDRQSREQLYEFIENT----NKTLLVVSHD 195
Cdd:PRK11247 152 PGLLLLDEPLGALDALTRIEMQDLIESLwqqhGFTVLLVTHD 193
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1-194 |
2.35e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 97.08 E-value: 2.35e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKE-----ILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPsagdirTEGSVYylpqiLEQF 75
Cdd:PRK13633 4 MIKCKNVSYKYESNEestekLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIP------SEGKVY-----VDGL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 76 DTQSIARALGVQKKLSAL-----REILEGIVTE------ENITVLDDnwDLEEKIKQALETWGLLDFTaDESMNRLSGGQ 144
Cdd:PRK13633 73 DTSDEENLWDIRNKAGMVfqnpdNQIVATIVEEdvafgpENLGIPPE--EIRERVDESLKKVGMYEYR-RHAPHLLSGGQ 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSH 194
Cdd:PRK13633 150 KQRVAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKkygiTIILITH 203
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
2-178 |
2.55e-22 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 94.73 E-value: 2.55e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHpDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyYLPQILEQFDTQS-- 79
Cdd:TIGR01189 1 LAARNLACSR-GERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGT--PLAEQRDEPHENIly 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 80 IARALGVQKKLSALreilegivteENITVLDDNWDLEEK-IKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQP 158
Cdd:TIGR01189 78 LGHLPGLKPELSAL----------ENLHFWAAIHGGAQRtIEDALAAVGLTGF-EDLPAAQLSAGQQRRLALARLWLSRR 146
|
170 180
....*....|....*....|
gi 639228517 159 DIILMDEPTNHLDRQSREQL 178
Cdd:TIGR01189 147 PLWILDEPTTALDKAGVALL 166
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
340-513 |
2.64e-22 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 95.02 E-value: 2.64e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 340 AEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI--------ERADFNSVYI---DQD 408
Cdd:cd03226 2 IENISFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSIllngkpikAKERRKSIGYvmqDVD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 409 YSMInhSLSVIQQ-AESFNWLPLPEHEVKTILSRF-LFGKEtwDKSCSVLSGGERMRLLLACLSITGkaPDIIILDEPTN 486
Cdd:cd03226 82 YQLF--TDSVREElLLGLKELDAGNEQAETVLKDLdLYALK--ERHPLSLSGGQKQRLAIAAALLSG--KDLLIFDEPTS 155
|
170 180 190
....*....|....*....|....*....|
gi 639228517 487 NLDLQNIEILTNAIRDYKG---TLLVISHD 513
Cdd:cd03226 156 GLDYKNMERVGELIRELAAqgkAVIVITHD 185
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
2-195 |
2.77e-22 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 94.90 E-value: 2.77e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQIleqfDTQSIA 81
Cdd:cd03262 1 IEIKNLHKSFGDFHVL-KGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKK----NINELR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGV---QKKLSALREILEGIvTEENITVLD-DNWDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQ 157
Cdd:cd03262 76 QKVGMvfqQFNLFPHLTVLENI-TLAPIKVKGmSKAEAEERALELLEKVGLADK-ADAYPAQLSGGQQQRVAIARALAMN 153
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 639228517 158 PDIILMDEPTNHLDRQSREQLYEFIEN---TNKTLLVVSHD 195
Cdd:cd03262 154 PKVMLFDEPTSALDPELVGEVLDVMKDlaeEGMTMVVVTHE 194
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-195 |
4.11e-22 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 95.05 E-value: 4.11e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRtegsvyylpqileqFDTQSI 80
Cdd:COG1127 5 MIEVRNLTKSFGDRVVL-DGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEIL--------------VDGQDI 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARAlgVQKKLSALR-EIleGIV----------T-EENI-------TVLDDNwDLEEKIKQALETWGLLDfTADESMNRLS 141
Cdd:COG1127 70 TGL--SEKELYELRrRI--GMLfqggalfdslTvFENVafplrehTDLSEA-EIRELVLEKLELVGLPG-AADKMPSELS 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 142 GGQKTKVLIA-GIeIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTL----LVVSHD 195
Cdd:COG1127 144 GGMRKRVALArAL-ALDPEILLYDEPTAGLDPITSAVIDELIRELRDELgltsVVVTHD 201
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
20-195 |
4.72e-22 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 94.81 E-value: 4.72e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSIARaLGVQKKLSALReILEG 99
Cdd:cd03219 18 DVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDG------EDITGLPPHEIAR-LGIGRTFQIPR-LFPE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 100 IVTEENITV---------------LDDNWDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIILMD 164
Cdd:cd03219 90 LTVLENVMVaaqartgsglllaraRREEREARERAEELLERVGLADL-ADRPAGELSYGQQRRLEIARALATDPKLLLLD 168
|
170 180 190
....*....|....*....|....*....|....
gi 639228517 165 EPTNHLDRQSREQLYEFIENTNK---TLLVVSHD 195
Cdd:cd03219 169 EPAAGLNPEETEELAELIRELRErgiTVLLVEHD 202
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
2-195 |
4.81e-22 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 93.41 E-value: 4.81e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFeNLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqfdtqsia 81
Cdd:cd03229 1 LELKNVSKRYGQKTVLN-DVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDG------------------ 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 ralgvqkklsalreilegivteENITVLDDNW-DLEEKIKQALETWGLL-DFTADES-MNRLSGGQKTKVLIAGIEIHQP 158
Cdd:cd03229 62 ----------------------EDLTDLEDELpPLRRRIGMVFQDFALFpHLTVLENiALGLSGGQQQRVALARALAMDP 119
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 639228517 159 DIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:cd03229 120 DVLLLDEPTSALDPITRREVRALLkslqAQLGITVVLVTHD 160
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
338-512 |
5.64e-22 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 92.83 E-value: 5.64e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWK-KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradFNSVYIDQ-DYSMINHS 415
Cdd:cd03228 1 IEFKNVSFSYPGRPKPVlKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEIL---IDGVDLRDlDLESLRKN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 416 LSVIQQaESfnwlplpehevktilsrFLFgketwdkSCSV----LSGGERMRLLLAclsitgKA----PDIIILDEPTNN 487
Cdd:cd03228 78 IAYVPQ-DP-----------------FLF-------SGTIreniLSGGQRQRIAIA------RAllrdPPILILDEATSA 126
|
170 180
....*....|....*....|....*..
gi 639228517 488 LDLQNIEILTNAIRDYKG--TLLVISH 512
Cdd:cd03228 127 LDPETEALILEALRALAKgkTVIVIAH 153
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1-195 |
7.94e-22 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 94.70 E-value: 7.94e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileqfdTQSI 80
Cdd:PRK11231 2 TLRTENLTVGYGTKRIL-NDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPI----------SMLS 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGvqKKLSALREILegiVTEENITVLD----------DNW-----DLEEKIKQALETWGLLDFtADESMNRLSGGQK 145
Cdd:PRK11231 71 SRQLA--RRLALLPQHH---LTPEGITVRElvaygrspwlSLWgrlsaEDNARVNQAMEQTRINHL-ADRRLTDLSGGQR 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTN---KTLLVVSHD 195
Cdd:PRK11231 145 QRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNtqgKTVVTVLHD 197
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1-195 |
9.60e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 95.18 E-value: 9.60e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQ-HPDKE-ILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDI------RTEGSVYYLPQ-- 70
Cdd:PRK13650 4 IIEVKNLTFKyKEDQEkYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIiidgdlLTEENVWDIRHki 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 71 --ILEQFDTQSIAR------ALGVQKKlsalreileGIVTEEnitvlddnwdLEEKIKQALETWGLLDFTADESmNRLSG 142
Cdd:PRK13650 84 gmVFQNPDNQFVGAtveddvAFGLENK---------GIPHEE----------MKERVNEALELVGMQDFKEREP-ARLSG 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 639228517 143 GQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHD 195
Cdd:PRK13650 144 GQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDdyqmTVISITHD 200
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
1-198 |
1.07e-21 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 94.04 E-value: 1.07e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKE----ILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFD 76
Cdd:COG4181 8 IIELRGLTKTVGTGAgeltIL-KGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAG------QDLFALD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 77 TQSIARALG-----VQKK------LSALreilegivteENITV---LDDNWDLEEKIKQALETWGLLDfTADESMNRLSG 142
Cdd:COG4181 81 EDARARLRArhvgfVFQSfqllptLTAL----------ENVMLpleLAGRRDARARARALLERVGLGH-RLDHYPAQLSG 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 143 GQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHDRTL 198
Cdd:COG4181 150 GEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRergtTLVLVTHDPAL 209
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
1-195 |
1.22e-21 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 93.90 E-value: 1.22e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyYLPQILEQFDTQSI 80
Cdd:TIGR02315 1 MLEVENLSKVYPNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEG---TDITKLRGKKLRKL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGV--Q-----KKLSALREILEGIV-TEENITVLDDNWDLEEKIK--QALETWGLLDFtADESMNRLSGGQKTKVLI 150
Cdd:TIGR02315 78 RRRIGMifQhynliERLTVLENVLHGRLgYKPTWRSLLGRFSEEDKERalSALERVGLADK-AYQRADQLSGGQQQRVAI 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 639228517 151 AGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHD 195
Cdd:TIGR02315 157 ARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKedgiTVIINLHQ 205
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
19-195 |
1.42e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 94.90 E-value: 1.42e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpQILEQFDTQSIARalgVQKKLSALREILE 98
Cdd:PRK13641 24 DNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGY-----HITPETGNKNLKK---LRKKVSLVFQFPE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 99 GIVTEEniTVLDD------NWDL-EEKIKQALETW----GLLDFTADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPT 167
Cdd:PRK13641 96 AQLFEN--TVLKDvefgpkNFGFsEDEAKEKALKWlkkvGLSEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPA 173
|
170 180 190
....*....|....*....|....*....|.
gi 639228517 168 NHLDRQSREQLYEFIENTNK---TLLVVSHD 195
Cdd:PRK13641 174 AGLDPEGRKEMMQLFKDYQKaghTVILVTHN 204
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
1-217 |
1.49e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 94.67 E-value: 1.49e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqFDTQSI 80
Cdd:PRK13644 1 MIRLENVSYSYPDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSG-----------IDTGDF 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKKLSALREILE----GIVTEENITVLDDNW-----DLEEKIKQALETWGLLDFTaDESMNRLSGGQKTKVLIA 151
Cdd:PRK13644 70 SKLQGIRKLVGIVFQNPEtqfvGRTVEEDLAFGPENLclppiEIRKRVDRALAEIGLEKYR-HRSPKTLSGGQGQCVALA 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 152 GIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTN---KTLLVVSHDRTLLNLLPKTAELSRKEMMLYG 217
Cdd:PRK13644 149 GILTMEPECLIFDEVTSMLDPDSGIAVLERIKKLHekgKTIVYITHNLEELHDADRIIVMDRGKIVLEG 217
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1-194 |
2.01e-21 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 92.82 E-value: 2.01e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNIT--YQHPDKEIL-FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqFDT 77
Cdd:cd03266 1 MITADALTkrFRDVKKTVQaVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDG-----------FDV 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 ----QSIARALGVqkkLSALREILEGIVTEENITVLDDNWDLE-EKIKQALE-TWGLLDF--TADESMNRLSGGQKTKVL 149
Cdd:cd03266 70 vkepAEARRRLGF---VSDSTGLYDRLTARENLEYFAGLYGLKgDELTARLEeLADRLGMeeLLDRRVGGFSTGMRQKVA 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 150 IAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSH 194
Cdd:cd03266 147 IARALVHDPPVLLLDEPTTGLDVMATRALREFIRqlrALGKCILFSTH 194
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
337-513 |
2.11e-21 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 92.95 E-value: 2.11e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE--------------RAD 399
Cdd:cd03257 1 LLEVKNLSVSFPTGGGSVKALDDVsfsIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIfdgkdllklsrrlrKIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 400 FNSV-YIDQD-YSMINHSLSVIQQ-AEsfnwlPLPEHEVKTILSRFLfgKETWDKSCSV-------------LSGGERMR 463
Cdd:cd03257 81 RKEIqMVFQDpMSSLNPRMTIGEQiAE-----PLRIHGKLSKKEARK--EAVLLLLVGVglpeevlnrypheLSGGQRQR 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 639228517 464 LLLAcLSITGKaPDIIILDEPTNNLDL----QNIEILTNAIRDYKGTLLVISHD 513
Cdd:cd03257 154 VAIA-RALALN-PKLLIADEPTSALDVsvqaQILDLLKKLQEELGLTLLFITHD 205
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
1-197 |
2.32e-21 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 93.66 E-value: 2.32e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQH-PDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSagdirtEGSVYYLPQILEQFDTQS 79
Cdd:PRK13648 7 IIVFKNVSFQYqSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVK------SGEIFYNNQAITDDNFEK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 80 IARALGVQKKlSALREILEGIVTE------ENITVLDDnwDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGI 153
Cdd:PRK13648 81 LRKHIGIVFQ-NPDNQFVGSIVKYdvafglENHAVPYD--EMHRRVSEALKQVDMLER-ADYEPNALSGGQKQRVAIAGV 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 154 EIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHDRT 197
Cdd:PRK13648 157 LALNPSVIILDEATSMLDPDARQNLLDLVrkvkSEHNITIISITHDLS 204
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
5-195 |
2.47e-21 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 92.43 E-value: 2.47e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 5 QNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpQILEqfDTQSIARAL 84
Cdd:cd03265 4 ENLVKKYGDFEAV-RGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGH-----DVVR--EPREVRRRI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 85 GVQKKLSALREILEGivtEENITVLD-----DNWDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPD 159
Cdd:cd03265 76 GIVFQDLSVDDELTG---WENLYIHArlygvPGAERRERIDELLDFVGLLEA-ADRLVKTYSGGMRRRLEIARSLVHRPE 151
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 639228517 160 IILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHD 195
Cdd:cd03265 152 VLFLDEPTIGLDPQTRAHVWEYIEKLKEefgmTILLTTHY 191
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1-195 |
2.74e-21 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 92.51 E-value: 2.74e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFenlNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG-SVYYLP------QILE 73
Cdd:COG3840 1 MLRLDDLTYRYGDFPLRF---DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGqDLTALPpaerpvSMLF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 74 Q----FDTQSIAR--ALGVQK--KLSAlreilegivtEEnitvlddnwdlEEKIKQALETWGLLDFtadesMNR----LS 141
Cdd:COG3840 78 QennlFPHLTVAQniGLGLRPglKLTA----------EQ-----------RAQVEQALERVGLAGL-----LDRlpgqLS 131
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 142 GGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:COG3840 132 GGQRQRVALARCLVRKRPILLLDEPFSALDPALRQEMLDLVdelcRERGLTVLMVTHD 189
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
25-195 |
2.88e-21 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 92.86 E-value: 2.88e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 25 VNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG-SVYYLPQILEQfDTQSIARALgvqkklsaLREILEGIVTe 103
Cdd:cd03237 22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELdTVSYKPQYIKA-DYEGTVRDL--------LSSITKDFYT- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 104 enitvlDDNWDLEekIKQALETWGLLdftaDESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSR----EQLY 179
Cdd:cd03237 92 ------HPYFKTE--IAKPLQIEQIL----DREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRlmasKVIR 159
|
170
....*....|....*.
gi 639228517 180 EFIENTNKTLLVVSHD 195
Cdd:cd03237 160 RFAENNEKTAFVVEHD 175
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
2-195 |
4.05e-21 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 91.86 E-value: 4.05e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLL-----TPSAGDIRTEGSVYYLPQILE--- 73
Cdd:cd03260 1 IELRDLNVYYGDKHAL-KDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNdlipgAPDEGEVLLDGKDIYDLDVDVlel 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 74 --------Q----FDTqSIAR--ALGVQKKLSALREILEGIVteenitvlddnwdleekiKQALETWGLLDFTADESMNR 139
Cdd:cd03260 80 rrrvgmvfQkpnpFPG-SIYDnvAYGLRLHGIKLKEELDERV------------------EEALRKAALWDEVKDRLHAL 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 140 -LSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK--TLLVVSHD 195
Cdd:cd03260 141 gLSGGQQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKeyTIVIVTHN 199
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
20-195 |
4.11e-21 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 92.45 E-value: 4.11e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLpqileqfdtqsIARALGVQKKLSAlreileg 99
Cdd:COG1134 44 DVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRVSAL-----------LELGAGFHPELTG------- 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 100 ivtEENI----TVLD-DNWDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAgIEIH-QPDIILMDEPTN----H 169
Cdd:COG1134 106 ---RENIylngRLLGlSRKEIDEKFDEIVEFAELGDF-IDQPVKTYSSGMRARLAFA-VATAvDPDILLVDEVLAvgdaA 180
|
170 180
....*....|....*....|....*.
gi 639228517 170 LDRQSREQLYEFIENtNKTLLVVSHD 195
Cdd:COG1134 181 FQKKCLARIRELRES-GRTVIFVSHS 205
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
4-196 |
4.76e-21 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 96.94 E-value: 4.76e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIR--TEGSVYYLPQILEQFDTQSia 81
Cdd:PRK11147 322 MENVNYQIDGKQLV-KDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHcgTKLEVAYFDQHRAELDPEK-- 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 ralgvqkklsalreilegivteeniTVLDdnwDLEEKiKQALETWG--------LLDF-----TADESMNRLSGGQKTKV 148
Cdd:PRK11147 399 -------------------------TVMD---NLAEG-KQEVMVNGrprhvlgyLQDFlfhpkRAMTPVKALSGGERNRL 449
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 149 LIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDR 196
Cdd:PRK11147 450 LLARLFLKPSNLLILDEPTNDLDVETLELLEELLDSYQGTVLLVSHDR 497
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
335-513 |
4.84e-21 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 91.64 E-value: 4.84e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 335 KILIKAEHINHAYQDKNIWKKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-------------ERA 398
Cdd:COG1136 2 SPLLELRNLTKSYGTGEGEVTALRGVslsIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVlidgqdisslserELA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 399 DF--NSV-YIDQDYSMINHsLSVIQQAEsfnwLPL---------PEHEVKTILSRF-LFGKEtwDKSCSVLSGGERMRLL 465
Cdd:COG1136 82 RLrrRHIgFVFQFFNLLPE-LTALENVA----LPLllagvsrkeRRERARELLERVgLGDRL--DHRPSQLSGGQQQRVA 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 639228517 466 LACLSITGkaPDIIILDEPTNNLDLQN----IEILTNAIRDYKGTLLVISHD 513
Cdd:COG1136 155 IARALVNR--PKLILADEPTGNLDSKTgeevLELLRELNRELGTTIVMVTHD 204
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-195 |
5.61e-21 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 94.37 E-value: 5.61e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG----------------- 63
Cdd:COG3839 3 SLELENVSKSYGGVEAL-KDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGrdvtdlppkdrniamvf 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 64 ---------SVYylpqileqfdtQSIARALGVQKklsalreilegiVTEENItvlddnwdlEEKIKQALETWGLLDFtad 134
Cdd:COG3839 82 qsyalyphmTVY-----------ENIAFPLKLRK------------VPKAEI---------DRRVREAAELLGLEDL--- 126
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 135 esMNR----LSGGQKTKVLIA-GIeIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:COG3839 127 --LDRkpkqLSGGQRQRVALGrAL-VREPKVFLLDEPLSNLDAKLRVEMRAEIkrlhRRLGTTTIYVTHD 193
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
18-199 |
9.53e-21 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 91.05 E-value: 9.53e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 18 FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLpqileqfdtqsIARALGVQKKLSALREI- 96
Cdd:cd03220 38 LKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVSSL-----------LGLGGGFNPELTGRENIy 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 97 ----LEGIVTEENITVLDDNWDLEEkikqaletwgLLDFtADESMNRLSGGQKTKVLIAgIEIH-QPDIILMDEPTNHLD 171
Cdd:cd03220 107 lngrLLGLSRKEIDEKIDEIIEFSE----------LGDF-IDLPVKTYSSGMKARLAFA-IATAlEPDILLIDEVLAVGD 174
|
170 180 190
....*....|....*....|....*....|.
gi 639228517 172 RQSREQLYEFIEN---TNKTLLVVSHDRTLL 199
Cdd:cd03220 175 AAFQEKCQRRLREllkQGKTVILVSHDPSSI 205
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
20-222 |
1.22e-20 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 90.85 E-value: 1.22e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYY--LPQILEQF-----DTQSIARALGVQKKLSA 92
Cdd:cd03267 39 GISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWkrRKKFLRRIgvvfgQKTQLWWDLPVIDSFYL 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 93 LREI--LEGIVTEENITVLDDNWDLEEKIKQaletwglldftadeSMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHL 170
Cdd:cd03267 119 LAAIydLPPARFKKRLDELSELLDLEELLDT--------------PVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGL 184
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 171 DRQSREQLYEFIENTNK----TLLVVSHDrtllnlLPKTAELSRKEMMLYGGN--YDS 222
Cdd:cd03267 185 DVVAQENIRNFLKEYNRergtTVLLTSHY------MKDIEALARRVLVIDKGRllYDG 236
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
4-194 |
1.28e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 92.03 E-value: 1.28e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQH----PDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIrtegsvyylpqILEQFD-TQ 78
Cdd:PRK13637 5 IENLTHIYmegtPFEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKI-----------IIDGVDiTD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 SIARALGVQKKLSALREILEGIVTEENITV----------LDDNwDLEEKIKQALETWGL-LDFTADESMNRLSGGQKTK 147
Cdd:PRK13637 74 KKVKLSDIRKKVGLVFQYPEYQLFEETIEKdiafgpinlgLSEE-EIENRVKRAMNIVGLdYEDYKDKSPFELSGGQKRR 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 148 VLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSH 194
Cdd:PRK13637 153 VAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIkelhKEYNMTIILVSH 203
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
2-195 |
1.62e-20 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 89.94 E-value: 1.62e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGdKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS------------VYYLP 69
Cdd:cd03264 1 LQLENLTKRYGKKRAL-DGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQdvlkqpqklrrrIGYLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 70 QileQFdtqsiaralGVQKKLSAlREILEGIVTEENItvldDNWDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVL 149
Cdd:cd03264 79 Q---EF---------GVYPNFTV-REFLDYIAWLKGI----PSKEVKARVDEVLELVNLGDR-AKKKIGSLSGGMRRRVG 140
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 150 IAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSHD 195
Cdd:cd03264 141 IAQALVGDPSILIVDEPTAGLDPEERIRFRNLLSElgEDRIVILSTHI 188
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1-194 |
1.72e-20 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 90.33 E-value: 1.72e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNIT---YQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqFDT 77
Cdd:cd03258 1 MIELKNVSkvfGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDG-----------TDL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 QSIARalgvqKKLSALREILEGIVTEENI----TVLD--------DNWD---LEEKIKQALETWGLLDFtADESMNRLSG 142
Cdd:cd03258 70 TLLSG-----KELRKARRRIGMIFQHFNLlssrTVFEnvalpleiAGVPkaeIEERVLELLELVGLEDK-ADAYPAQLSG 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 143 GQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSH 194
Cdd:cd03258 144 GQKQRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRelglTIVLITH 199
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
2-265 |
2.11e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 91.40 E-value: 2.11e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPD-KEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAgdirtegsvyylpqileqfDTQSI 80
Cdd:PRK13640 6 VEFKHVSFTYPDsKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDD-------------------NPNSK 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKKLSALREILE--GIVTEE------NITVLDD-NWDLEEK----------IKQALETWGLLDFTADESMNrLS 141
Cdd:PRK13640 67 ITVDGITLTAKTVWDIREkvGIVFQNpdnqfvGATVGDDvAFGLENRavprpemikiVRDVLADVGMLDYIDSEPAN-LS 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 142 GGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHDRTLLNLLPKTAELSRKEMMLYG 217
Cdd:PRK13640 146 GGQKQRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIrklkKKNNLTVISITHDIDEANMADQVLVLDDGKLLAQG 225
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 218 GNYDSYKEQKQIQQ--------NALQNSIKNTENALKKAKATERETLERQQKLDAK 265
Cdd:PRK13640 226 SPVEIFSKVEMLKEigldipfvYKLKNKLKEKGISVPQEINTEEKLVQYLCQLNSK 281
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
1-201 |
2.66e-20 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 90.60 E-value: 2.66e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSI 80
Cdd:PRK13548 2 MLEARNLSVRLGGRTLL-DDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNG------RPLADWSPAEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKKLSAL------REILE------GIVTEENITVLDdnwdleekikQALETWGLLDFtADESMNRLSGGQKTKV 148
Cdd:PRK13548 75 ARRRAVLPQHSSLsfpftvEEVVAmgraphGLSRAEDDALVA----------AALAQVDLAHL-AGRDYPQLSGGEQQRV 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639228517 149 LIAGI--EIHQPD----IILMDEPTNHLDRQSREQL----YEFIENTNKTLLVVSHDrtlLNL 201
Cdd:PRK13548 144 QLARVlaQLWEPDgpprWLLLDEPTSALDLAHQHHVlrlaRQLAHERGLAVIVVLHD---LNL 203
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
338-527 |
3.66e-20 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 89.09 E-value: 3.66e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-------------ERADF- 400
Cdd:cd03255 1 IELKNLSKTYGGGGEKVQALKGVslsIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVrvdgtdisklsekELAAFr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 401 -NSV-YIDQDYSMINHsLSVIQQAE---SFNWLPLPEHEVK--TILSRFLFGKETwDKSCSVLSGGERMRLLLAcLSITG 473
Cdd:cd03255 81 rRHIgFVFQSFNLLPD-LTALENVElplLLAGVPKKERRERaeELLERVGLGDRL-NHYPSELSGGQQQRVAIA-RALAN 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 474 KaPDIIILDEPTNNLDLQN----IEILTNAIRDYKGTLLVISHDDVFSEeinIETRIL 527
Cdd:cd03255 158 D-PKIILADEPTGNLDSETgkevMELLRELNKEAGTTIVVVTHDPELAE---YADRII 211
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
2-211 |
3.77e-20 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 87.59 E-value: 3.77e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDI-RTEGS-VYYLPQileqfdtqs 79
Cdd:cd03223 1 IELENLSLATPDGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIgMPEGEdLLFLPQ--------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 80 iaralgvQKKLSA--LREILegivteenitvlddnwdleekikqaLETWglldftadesMNRLSGGQKTKVLIAGIEIHQ 157
Cdd:cd03223 72 -------RPYLPLgtLREQL-------------------------IYPW----------DDVLSGGEQQRLAFARLLLHK 109
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 639228517 158 PDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLLNLLPKTAELSRK 211
Cdd:cd03223 110 PKFVFLDEATSALDEESEDRLYQLLKELGITVISVGHRPSLWKFHDRVLDLDGE 163
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
24-513 |
4.06e-20 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 93.72 E-value: 4.06e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 24 IVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyyLPQILEQF---DTQSIARALgVQKKLSA-------- 92
Cdd:PRK13409 95 IPKEGKVTGILGPNGIGKTTAVKILSGELIPNLGDYEEEPS---WDEVLKRFrgtELQNYFKKL-YNGEIKVvhkpqyvd 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 93 -LREILEGIVTEEnITVLDDNWDLEEKIKQaLEtwglLDFTADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLD 171
Cdd:PRK13409 171 lIPKVFKGKVREL-LKKVDERGKLDEVVER-LG----LENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLD 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 172 RQSR----EQLYEFIENtnKTLLVVSHDRTLLNLLPKTAELsrkemmLYG--GNYdsykeqkqiqqnalqnsikntenal 245
Cdd:PRK13409 245 IRQRlnvaRLIRELAEG--KYVLVVEHDLAVLDYLADNVHI------AYGepGAY------------------------- 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 246 kkakateretlerqqkldakGKKKQEKAgvAKIMMNT-----LRNnaENstAKIRDthsdkiEGLSQELQQLRRGVpltd 320
Cdd:PRK13409 292 --------------------GVVSKPKG--VRVGINEylkgyLPE--EN--MRIRP------EPIEFEERPPRDES---- 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 321 qmklgfdqanlhRGKILIKAEHINHAYQDKNiwkkpLDV---VVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE- 396
Cdd:PRK13409 336 ------------ERETLVEYPDLTKKLGDFS-----LEVeggEIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDp 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 397 --RADFNSVYIDQDYSM-INHSLSVIQQAESFNWLplpEHEvktILSRFLFGKeTWDKSCSVLSGGERMRLLLA-CLSit 472
Cdd:PRK13409 399 elKISYKPQYIKPDYDGtVEDLLRSITDDLGSSYY---KSE---IIKPLQLER-LLDKNVKDLSGGELQRVAIAaCLS-- 469
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 639228517 473 gKAPDIIILDEPTNNLDLQNIEILTNAIRDY----KGTLLVISHD 513
Cdd:PRK13409 470 -RDADLYLLDEPSAHLDVEQRLAVAKAIRRIaeerEATALVVDHD 513
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
6-194 |
4.41e-20 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 89.21 E-value: 4.41e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 6 NITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqFDTQSIaralg 85
Cdd:cd03254 7 NVNFSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDG-----------IDIRDI----- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 86 vqkKLSALREILeGIVTE----------ENITvLDDNWDLEEKIKQALETWGLLDF----------TADESMNRLSGGQK 145
Cdd:cd03254 71 ---SRKSLRSMI-GVVLQdtflfsgtimENIR-LGRPNATDEEVIEAAKEAGAHDFimklpngydtVLGENGGNLSQGER 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENT--NKTLLVVSH 194
Cdd:cd03254 146 QLLAIARAMLRDPKILILDEATSNIDTETEKLIQEALEKLmkGRTSIIIAH 196
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-196 |
4.74e-20 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 91.70 E-value: 4.74e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRtegsvyylpqileqFDTQSI 80
Cdd:COG3842 5 ALELENVSKRYGDVTAL-DDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRIL--------------LDGRDV 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARaLGVQKklsalREIleGIVTEE-----NITVLD-----------DNWDLEEKIKQALETWGLLDFtADESMNRLSGGQ 144
Cdd:COG3842 70 TG-LPPEK-----RNV--GMVFQDyalfpHLTVAEnvafglrmrgvPKAEIRARVAELLELVGLEGL-ADRYPHQLSGGQ 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHDR 196
Cdd:COG3842 141 QQRVALARALAPEPRVLLLDEPLSALDAKLREEMREELrrlqRELGITFIYVTHDQ 196
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
2-520 |
5.47e-20 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 92.94 E-value: 5.47e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLltpsAGDIRTEGSVYYLPQILEQfdtqsiA 81
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVL-KNISFTIEEGEVLGILGRSGAGKSVLMHVLRGM----DQYEPTSGRIIYHVALCEK------C 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGVQKKLSALREILEGIVTEENItvldDNWDLEEKIKQAL---------ETWGL----------------LDFTADES 136
Cdd:TIGR03269 70 GYVERPSKVGEPCPVCGGTLEPEEV----DFWNLSDKLRRRIrkriaimlqRTFALygddtvldnvlealeeIGYEGKEA 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 137 MNR--------------------LSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQS----REQLYEFIENTNKTLLVV 192
Cdd:TIGR03269 146 VGRavdliemvqlshrithiardLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTaklvHNALEEAVKASGISMVLT 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 193 SHDRTLLnllpktAELSRKEMMLYGGnydsykEQKQIQqnalqNSIKNTENALKKAKATERETLERQqkldakgkkkqek 272
Cdd:TIGR03269 226 SHWPEVI------EDLSDKAIWLENG------EIKEEG-----TPDEVVAVFMEGVSEVEKECEVEV------------- 275
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 273 agvakimmntlrnnaENSTAKIRDthsdkiegLSQELQQLRRGVpltdqmklgfdqanlhrgkilIKAehinhayqdkni 352
Cdd:TIGR03269 276 ---------------GEPIIKVRN--------VSKRYISVDRGV---------------------VKA------------ 299
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 353 wKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE-------------------RADFNSVYIDQDYSMIN 413
Cdd:TIGR03269 300 -VDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNvrvgdewvdmtkpgpdgrgRAKRYIGILHQEYDLYP 378
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 414 HSlSVIQQAESFNWLPLPE--------HEVKTILSRFLFGKETWDKSCSVLSGGERMRLLLACLSItgKAPDIIILDEPT 485
Cdd:TIGR03269 379 HR-TVLDNLTEAIGLELPDelarmkavITLKMVGFDEEKAEEILDKYPDELSEGERHRVALAQVLI--KEPRIVILDEPT 455
|
570 580 590
....*....|....*....|....*....|....*....
gi 639228517 486 NNLD----LQNIEILTNAIRDYKGTLLVISHDDVFSEEI 520
Cdd:TIGR03269 456 GTMDpitkVDVTHSILKAREEMEQTFIIVSHDMDFVLDV 494
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
15-183 |
5.73e-20 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 88.01 E-value: 5.73e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 15 EILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQILEQfdTQSIARALGVQKKLSAlR 94
Cdd:PRK13539 15 RVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEA--CHYLGHRNAMKPALTV-A 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 95 EILEGivteenitvlddnW-----DLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNH 169
Cdd:PRK13539 92 ENLEF-------------WaaflgGEELDIAAALEAVGLAPL-AHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAA 157
|
170
....*....|....
gi 639228517 170 LDRQSREQLYEFIE 183
Cdd:PRK13539 158 LDAAAVALFAELIR 171
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
4-195 |
7.50e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 89.41 E-value: 7.50e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQILEqfdtqsiara 83
Cdd:PRK13647 7 VEDLHFRYKDGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKW---------- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 84 lgVQKKLsalreileGIVTEE------NITVLDD------NWDL-----EEKIKQALETWGLLDFtADESMNRLSGGQKT 146
Cdd:PRK13647 77 --VRSKV--------GLVFQDpddqvfSSTVWDDvafgpvNMGLdkdevERRVEEALKAVRMWDF-RDKPPYHLSYGQKK 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 639228517 147 KVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHD 195
Cdd:PRK13647 146 RVAIAGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDrlhNQGKTVIVATHD 197
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
4-213 |
8.63e-20 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 87.85 E-value: 8.63e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqfdtQSIARA 83
Cdd:cd03292 3 FINVTKTYPNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNG--------------QDVSDL 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 84 LGvqKKLSALREILeGIVTEENITVLDDN----------------WDLEEKIKQALETWGLLDfTADESMNRLSGGQKTK 147
Cdd:cd03292 69 RG--RAIPYLRRKI-GVVFQDFRLLPDRNvyenvafalevtgvppREIRKRVPAALELVGLSH-KHRALPAELSGGEQQR 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 148 VLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK---TLLVVSHDRTLLNLL-PKTAELSRKEM 213
Cdd:cd03292 145 VAIARAIVNSPTILIADEPTGNLDPDTTWEIMNLLKKINKagtTVVVATHAKELVDTTrHRVIALERGKL 214
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
4-218 |
1.70e-19 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 87.56 E-value: 1.70e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpQI--LEQFDTQSIA 81
Cdd:cd03261 3 LRGLTKSFGGRTVL-KGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGE-----DIsgLSEAELYRLR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGVQKKLSALreiLEGIVTEENI-------TVLDDNWdLEEKIKQALETWGLLDfTADESMNRLSGGQKTKVLIAGIE 154
Cdd:cd03261 77 RRMGMLFQSGAL---FDSLTVFENVafplrehTRLSEEE-IREIVLEKLEAVGLRG-AEDLYPAELSGGMKKRVALARAL 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 155 IHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTL----LVVSHDrtllnlLPKTAELSRKEMMLYGG 218
Cdd:cd03261 152 ALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELgltsIMVTHD------LDTAFAIADRIAVLYDG 213
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
1-194 |
1.77e-19 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 87.33 E-value: 1.77e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYqhpdkeiLFENL----NFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileqfd 76
Cdd:PRK10771 1 MLKLTDITW-------LYHHLpmrfDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDH---------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 77 tqsiARALGVQKKLSAL---REILEGIVTEENITV-----LDDNWDLEEKIKQALETWGLLDFtadesMNRL----SGGQ 144
Cdd:PRK10771 64 ----TTTPPSRRPVSMLfqeNNLFSHLTVAQNIGLglnpgLKLNAAQREKLHAIARQMGIEDL-----LARLpgqlSGGQ 134
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLD---RQSREQLYEFI-ENTNKTLLVVSH 194
Cdd:PRK10771 135 RQRVALARCLVREQPILLLDEPFSALDpalRQEMLTLVSQVcQERQLTLLMVSH 188
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
2-194 |
1.85e-19 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 86.89 E-value: 1.85e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileqFDTQSIA 81
Cdd:cd03268 1 LKTNDLTKTYGKKRVL-DDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSY--------QKNIEAL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGVqkklsalreILEG------IVTEENITVLDDNWDLEEK-IKQALETWGLLDfTADESMNRLSGGQKTKVLIAGIE 154
Cdd:cd03268 72 RRIGA---------LIEApgfypnLTARENLRLLARLLGIRKKrIDEVLDVVGLKD-SAKKKVKGFSLGMKQRLGIALAL 141
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 639228517 155 IHQPDIILMDEPTNHLDRQSREQLYEFIEN---TNKTLLVVSH 194
Cdd:cd03268 142 LGNPDLLILDEPTNGLDPDGIKELRELILSlrdQGITVLISSH 184
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
2-228 |
1.87e-19 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 87.54 E-value: 1.87e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQH-PDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSI 80
Cdd:cd03252 1 ITFEHVRFRYkPDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDG------HDLALADPAWL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGV--QKKLSALREIlegivtEENITVLDDNWDLeEKIKQALETWGLLDFTAD----------ESMNRLSGGQKTKV 148
Cdd:cd03252 75 RRQVGVvlQENVLFNRSI------RDNIALADPGMSM-ERVIEAAKLAGAHDFISElpegydtivgEQGAGLSGGQRQRI 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 149 LIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSH--------DRTLLNLLPKTAELSRKEMMLYGG 218
Cdd:cd03252 148 AIARALIHNPRILIFDEATSALDYESEHAIMRNMHDicAGRTVIIIAHrlstvknaDRIIVMEKGRIVEQGSHDELLAEN 227
|
250
....*....|
gi 639228517 219 NYDSYKEQKQ 228
Cdd:cd03252 228 GLYAYLYQLQ 237
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
14-195 |
2.10e-19 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 88.12 E-value: 2.10e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 14 KEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSIARALGVqkklsal 93
Cdd:PRK10253 19 KYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDG------EHIQHYASKEVARRIGL------- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 94 reILEGIVTEENITV-------------LDDNW--DLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQP 158
Cdd:PRK10253 86 --LAQNATTPGDITVqelvargryphqpLFTRWrkEDEEAVTKAMQATGITHL-ADQSVDTLSGGQRQRAWIAMVLAQET 162
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 639228517 159 DIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHD 195
Cdd:PRK10253 163 AIMLLDEPTTWLDISHQIDLLELLSELNRekgyTLAAVLHD 203
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1-207 |
2.39e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 88.32 E-value: 2.39e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpQILEQfDTQSI 80
Cdd:PRK13652 3 LIETRDLCYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGE-----PITKE-NIREV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKKLSAlREILEGIVtEENITVLDDNWDLEE-----KIKQALETWGLLDFTaDESMNRLSGGQKTKVLIAGIEI 155
Cdd:PRK13652 77 RKFVGLVFQNPD-DQIFSPTV-EQDIAFGPINLGLDEetvahRVSSALHMLGLEELR-DRVPHHLSGGEKKRVAIAGVIA 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 639228517 156 HQPDIILMDEPTNHLDRQSREQLYEFIENTNKTL-LVVSHDRTLLNLLPKTAE 207
Cdd:PRK13652 154 MEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETYgMTVIFSTHQLDLVPEMAD 206
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
1-183 |
3.31e-19 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 86.01 E-value: 3.31e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKeILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpQILEQFDtqSI 80
Cdd:PRK13538 1 MLEARNLACERDER-ILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGE-----PIRRQRD--EY 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARAL-------GVQKKLSAlreilegivtEENITV---LDDNWDlEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLI 150
Cdd:PRK13538 73 HQDLlylghqpGIKTELTA----------LENLRFyqrLHGPGD-DEALWEALAQVGLAGF-EDVPVRQLSAGQQRRVAL 140
|
170 180 190
....*....|....*....|....*....|...
gi 639228517 151 AGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE 183
Cdd:PRK13538 141 ARLWLTRAPLWILDEPFTAIDKQGVARLEALLA 173
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
2-195 |
4.06e-19 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 86.52 E-value: 4.06e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG-SVYYLPQILEQFDT--- 77
Cdd:cd03300 1 IELENVSKFYGGFVAL-DGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGkDITNLPPHKRPVNTvfq 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 -----------QSIARALGVQKKLSAlreilegivteenitvlddnwDLEEKIKQALETWGLLDFtADESMNRLSGGQKT 146
Cdd:cd03300 80 nyalfphltvfENIAFGLRLKKLPKA---------------------EIKERVAEALDLVQLEGY-ANRKPSQLSGGQQQ 137
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 639228517 147 KVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHD 195
Cdd:cd03300 138 RVAIARALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKelgiTFVFVTHD 190
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
24-513 |
4.88e-19 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 90.23 E-value: 4.88e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 24 IVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyyLPQILEQF---DTQSIARALgVQKKLSA-------- 92
Cdd:COG1245 95 VPKKGKVTGILGPNGIGKSTALKILSGELKPNLGDYDEEPS---WDEVLKRFrgtELQDYFKKL-ANGEIKVahkpqyvd 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 93 ---------LREILEGIvteenitvlDDNWDLEEKIKQaLEtwglLDFTADESMNRLSGGQKTKVLIAGIEIHQPDIILM 163
Cdd:COG1245 171 lipkvfkgtVRELLEKV---------DERGKLDELAEK-LG----LENILDRDISELSGGELQRVAIAAALLRDADFYFF 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 164 DEPTNHLD-RQS-------REqlyefIENTNKTLLVVSHDRTLLNLLPKTAELsrkemmLYG--GNYdsykeqkqiqqna 233
Cdd:COG1245 237 DEPSSYLDiYQRlnvarliRE-----LAEEGKYVLVVEHDLAILDYLADYVHI------LYGepGVY------------- 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 234 lqnsikntenalkkakateretlerqqkldakG---KKKQEKAGVakimmntlrNN-------AENstAKIRDthsDKIE 303
Cdd:COG1245 293 --------------------------------GvvsKPKSVRVGI---------NQyldgylpEEN--VRIRD---EPIE 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 304 glsQELQQLRRGVpltdqmklgfdqanlhRGKILIKAEHINHAYQDKNiwkkpLDV---VVSSGERILIIGENGSGKTTL 380
Cdd:COG1245 327 ---FEVHAPRREK----------------EEETLVEYPDLTKSYGGFS-----LEVeggEIREGEVLGIVGPNGIGKTTF 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 381 IKLLLGQMKPSEGTIERADFNSV---YIDQDYSMinhslSVIQQAESFNWLPLPEHEVKTILSRFLFGKETWDKSCSVLS 457
Cdd:COG1245 383 AKILAGVLKPDEGEVDEDLKISYkpqYISPDYDG-----TVEEFLRSANTDDFGSSYYKTEIIKPLGLEKLLDKNVKDLS 457
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 639228517 458 GGERMRLLLA-CLSitgKAPDIIILDEPTNNLDLQNIEILTNAIRDY----KGTLLVISHD 513
Cdd:COG1245 458 GGELQRVAIAaCLS---RDADLYLLDEPSAHLDVEQRLAVAKAIRRFaenrGKTAMVVDHD 515
|
|
| PQQ_ABC_ATP |
TIGR03864 |
ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Members of ... |
1-178 |
7.29e-19 |
|
ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Members of this protein family are the ATP-binding subunit of an ABC transporter system that is associated with PQQ biosynthesis and PQQ-dependent alcohol dehydrogenases. While this family shows homology to several efflux ABC transporter subunits, the presence of a periplasmic substrate-binding protein and association with systems for catabolism of alcohols suggests a role in import rather than detoxification. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 274822 [Multi-domain] Cd Length: 236 Bit Score: 85.81 E-value: 7.29e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqFDTQSI 80
Cdd:TIGR03864 1 ALEVAGLSFRYGARRAL-DDVSFTVRPGRFVALLGPNGAGKSTLFSLLTRLYVAQSGQISVAG-----------HDLRRA 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARAlgvqkklsALREIleGIVTEENITVLD----DNW----DL--------EEKIKQALETWGLLDfTADESMNRLSGGQ 144
Cdd:TIGR03864 69 PRA--------ALARL--GVVFQQPTLDLDlsvrQNLryhaALhglsraeaRARIAELLARLGLAE-RADDKVRELNGGH 137
|
170 180 190
....*....|....*....|....*....|....
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQL 178
Cdd:TIGR03864 138 RRRVEIARALLHRPALLLLDEPTVGLDPASRAAI 171
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
2-194 |
8.13e-19 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 85.74 E-value: 8.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQ-HPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSI 80
Cdd:cd03253 1 IEFENVTFAyDPGRPVL-KDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDG------QDIREVTLDSL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKKLSAL--REILEGI------VTEENITVLDDNWDLEEKIKQALETWgllDFTADESMNRLSGGQKTKVLIAG 152
Cdd:cd03253 74 RRAIGVVPQDTVLfnDTIGYNIrygrpdATDEEVIEAAKAAQIHDKIMRFPDGY---DTIVGERGLKLSGGEKQRVAIAR 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 639228517 153 IEIHQPDIILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSH 194
Cdd:cd03253 151 AILKNPPILLLDEATSALDTHTEREIQAALRDvsKGRTTIVIAH 194
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
2-194 |
1.10e-18 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 85.36 E-value: 1.10e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEI-LFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqFDTQSI 80
Cdd:cd03251 1 VEFKNVTFRYPGDGPpVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDG-----------HDVRDY 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 aralgvqkKLSALREILeGIVT----------EENITVLDDNWDLEEkIKQALETWGLLDFTAD----------ESMNRL 140
Cdd:cd03251 70 --------TLASLRRQI-GLVSqdvflfndtvAENIAYGRPGATREE-VEEAARAANAHEFIMElpegydtvigERGVKL 139
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 141 SGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSH 194
Cdd:cd03251 140 SGGQRQRIAIARALLKDPPILILDEATSALDTESERLVQAALERlmKNRTTFVIAH 195
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
2-194 |
1.16e-18 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 83.52 E-value: 1.16e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKE-ILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIrtegsvyylpqILEQFDTQSI 80
Cdd:cd03247 1 LSINNVSFSYPEQEqQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEI-----------TLDGVPVSDL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALgvqkklsalreilegivtEENITVLDdnwdleekikQALEtwgLLDFTADESMN-RLSGGQKTKVLIAGIEIHQPD 159
Cdd:cd03247 70 EKAL------------------SSLISVLN----------QRPY---LFDTTLRNNLGrRFSGGERQRLALARILLQDAP 118
|
170 180 190
....*....|....*....|....*....|....*..
gi 639228517 160 IILMDEPTNHLDRQSREQLYE--FIENTNKTLLVVSH 194
Cdd:cd03247 119 IVLLDEPTVGLDPITERQLLSliFEVLKDKTLIWITH 155
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
327-513 |
1.26e-18 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 89.51 E-value: 1.26e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 327 DQANLHRGKIL--IKAEHINHAY--QDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeradfns 402
Cdd:COG2274 461 GRSKLSLPRLKgdIELENVSFRYpgDSPPVLDN-ISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRI------- 532
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 403 vYID-QDYSMIN-----HSLSVI-QQAESFN---------WLP-LPEHEVKTIL---------SRFLFGKETW--DKScS 454
Cdd:COG2274 533 -LIDgIDLRQIDpaslrRQIGVVlQDVFLFSgtirenitlGDPdATDEEIIEAArlaglhdfiEALPMGYDTVvgEGG-S 610
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639228517 455 VLSGGERMRLLLA-CLSitgKAPDIIILDEPTNNLDLQNIEILTNAIRDYKG--TLLVISHD 513
Cdd:COG2274 611 NLSGGQRQRLAIArALL---RNPRILILDEATSALDAETEAIILENLRRLLKgrTVIIIAHR 669
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
1-171 |
1.26e-18 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 85.05 E-value: 1.26e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQileqfdtqsi 80
Cdd:COG1126 1 MIEIENLHKSFGDLEVL-KGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSK---------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 aralgvqKKLSALR-EIleGIV----------T-EENIT-----VLddNWDLEEKIKQA---LETWGLLDFtADESMNRL 140
Cdd:COG1126 70 -------KDINKLRrKV--GMVfqqfnlfphlTvLENVTlapikVK--KMSKAEAEERAmelLERVGLADK-ADAYPAQL 137
|
170 180 190
....*....|....*....|....*....|.
gi 639228517 141 SGGQKTKVLIAGIEIHQPDIILMDEPTNHLD 171
Cdd:COG1126 138 SGGQQQRVAIARALAMEPKVMLFDEPTSALD 168
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
6-194 |
1.29e-18 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 86.33 E-value: 1.29e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 6 NITYQ--HPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYlpqileqfDTQSIARA 83
Cdd:PRK13643 8 NYTYQpnSPFASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVS--------STSKQKEI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 84 LGVQKKLSALREILEGIVTEEniTVLDD------NWDLE----EKIK-QALETWGLLDFTADESMNRLSGGQKTKVLIAG 152
Cdd:PRK13643 80 KPVRKKVGVVFQFPESQLFEE--TVLKDvafgpqNFGIPkekaEKIAaEKLEMVGLADEFWEKSPFELSGGQMRRVAIAG 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 639228517 153 IEIHQPDIILMDEPTNHLDRQSR---EQLYEFIENTNKTLLVVSH 194
Cdd:PRK13643 158 ILAMEPEVLVLDEPTAGLDPKARiemMQLFESIHQSGQTVVLVTH 202
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
25-202 |
2.41e-18 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 88.30 E-value: 2.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 25 VNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQILEQFDTQSIaralgvqkklsalREILEGIVTEE 104
Cdd:COG1245 363 IREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLKISYKPQYISPDYDGTV-------------EEFLRSANTDD 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 105 nitvLDDNWdLEEKIKQALEtwglLDFTADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI-- 182
Cdd:COG1245 430 ----FGSSY-YKTEIIKPLG----LEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIrr 500
|
170 180
....*....|....*....|..
gi 639228517 183 --ENTNKTLLVVSHDRTLLNLL 202
Cdd:COG1245 501 faENRGKTAMVVDHDIYLIDYI 522
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
2-194 |
4.53e-18 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 81.32 E-value: 4.53e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileQFDTQSIA 81
Cdd:cd03216 1 LELRGITKRFGGVKAL-DGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEV-------SFASPRDA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGVqkklsalreileGIVTEenitvlddnwdleekikqaletwglldftadesmnrLSGGQKTKVLIAGIEIHQPDII 161
Cdd:cd03216 73 RRAGI------------AMVYQ------------------------------------LSVGERQMVEIARALARNARLL 104
|
170 180 190
....*....|....*....|....*....|....*.
gi 639228517 162 LMDEPTNHLDRQSREQLYEFIENT---NKTLLVVSH 194
Cdd:cd03216 105 ILDEPTAALTPAEVERLFKVIRRLraqGVAVIFISH 140
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
1-195 |
4.83e-18 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 82.73 E-value: 4.83e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQnITYQHPDKEIlfeNLNFIVNkGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileqFDTQsI 80
Cdd:cd03297 1 MLCVD-IEKRLPDFTL---KIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVL--------FDSR-K 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKklsalREIleGIVTE-----------ENIT-VLDDNWDLEEKIkQALETWGLLDFT--ADESMNRLSGGQKT 146
Cdd:cd03297 67 KINLPPQQ-----RKI--GLVFQqyalfphlnvrENLAfGLKRKRNREDRI-SVDELLDLLGLDhlLNRYPAQLSGGEKQ 138
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 639228517 147 KVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTL----LVVSHD 195
Cdd:cd03297 139 RVALARALAAQPELLLLDEPFSALDRALRLQLLPELKQIKKNLnipvIFVTHD 191
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-200 |
5.91e-18 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 86.80 E-value: 5.91e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKE-ILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSI 80
Cdd:PRK11160 339 LTLNNVSFTYPDQPqPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNG------QPIADYSEAAL 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGV--QKK--LSA-LReilegivteENITVLDDNWDlEEKIKQALETWGL---LDftADESMN--------RLSGGQ 144
Cdd:PRK11160 413 RQAISVvsQRVhlFSAtLR---------DNLLLAAPNAS-DEALIEVLQQVGLeklLE--DDKGLNawlgeggrQLSGGE 480
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQ----LYEFIEntNKTLLVVSHDRTLLN 200
Cdd:PRK11160 481 QRRLGIARALLHDAPLLLLDEPTEGLDAETERQilelLAEHAQ--NKTVLMITHRLTGLE 538
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
361-512 |
7.60e-18 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 81.11 E-value: 7.60e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE--RADFNSVYIDQDYSMINhslSVIQQAEsfnwlplpehevkti 438
Cdd:cd03246 25 IEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRldGADISQWDPNELGDHVG---YLPQDDE--------------- 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 439 lsrfLFGKETWDkscSVLSGGERMRLLLA-CLSitgKAPDIIILDEPTNNLDLQNIEILTNAIRDYK---GTLLVISH 512
Cdd:cd03246 87 ----LFSGSIAE---NILSGGQRQRLGLArALY---GNPRILVLDEPNSHLDVEGERALNQAIAALKaagATRIVIAH 154
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
2-194 |
7.91e-18 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 83.64 E-value: 7.91e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHP-----DKEILFeNLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVyylpqILEQFD 76
Cdd:PRK13649 3 INLQNVSYTYQagtpfEGRALF-DVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTL-----ITSTSK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 77 TQSIARalgVQKKLSALREILEGIVTEEniTVLDD------NWDL--EEKIKQALETWGLLDFTA---DESMNRLSGGQK 145
Cdd:PRK13649 77 NKDIKQ---IRKKVGLVFQFPESQLFEE--TVLKDvafgpqNFGVsqEEAEALAREKLALVGISEslfEKNPFELSGGQM 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK---TLLVVSH 194
Cdd:PRK13649 152 RRVAIAGILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQsgmTIVLVTH 203
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
6-194 |
8.20e-18 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 86.70 E-value: 8.20e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 6 NITYQH--------PDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDT 77
Cdd:TIGR00958 478 LIEFQDvsfsypnrPDVPVL-KGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDG------VPLVQYDH 550
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 QSIARalgvQKKLSALREILEGIVTEENITV-LDDNWDleEKIKQALETWGLLDFTA----------DESMNRLSGGQKT 146
Cdd:TIGR00958 551 HYLHR----QVALVGQEPVLFSGSVRENIAYgLTDTPD--EEIMAAAKAANAHDFIMefpngydtevGEKGSQLSGGQKQ 624
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 147 KVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSH 194
Cdd:TIGR00958 625 RIAIARALVRKPRVLILDEATSALDAECEQLLQESRSRASRTVLLIAH 672
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
14-195 |
8.36e-18 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 82.77 E-value: 8.36e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 14 KEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS-----------VYYLPQILEQFDTQSIAR 82
Cdd:cd03299 11 KEFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKditnlppekrdISYVPQNYALFPHMTVYK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 83 --ALGVQKKLSALREIlegivteenitvlddnwdlEEKIKQALETWGLldftaDESMNR----LSGGQKTKVLIAGIEIH 156
Cdd:cd03299 91 niAYGLKKRKVDKKEI-------------------ERKVLEIAEMLGI-----DHLLNRkpetLSGGEQQRVAIARALVV 146
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 639228517 157 QPDIILMDEPTNHLDRQSREQLYE----FIENTNKTLLVVSHD 195
Cdd:cd03299 147 NPKILLLDEPFSALDVRTKEKLREelkkIRKEFGVTVLHVTHD 189
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-195 |
8.44e-18 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 83.37 E-value: 8.44e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHP----DKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqilEQFD 76
Cdd:COG4525 3 MLTVRHVSVRYPgggqPQPAL-QDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDG---------VPVT 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 77 TQSIARALGVQKK-----LSALREI-----LEGIvteenitvlddnwDLEEKIKQALETW---GLLDFtADESMNRLSGG 143
Cdd:COG4525 73 GPGADRGVVFQKDallpwLNVLDNVafglrLRGV-------------PKAERRARAEELLalvGLADF-ARRRIWQLSGG 138
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 144 QKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:COG4525 139 MRQRVGIARALAADPRFLLMDEPFGALDALTREQMQELLldvwQRTGKGVFLITHS 194
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
361-513 |
1.02e-17 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 82.84 E-value: 1.02e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIErADFNSV-----YIDQDYSMINHSL--SVIQQAESFNWLplpeh 433
Cdd:cd03237 22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIE-IELDTVsykpqYIKADYEGTVRDLlsSITKDFYTHPYF----- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 434 evKTILSRFLFGKETWDKSCSVLSGGERMRL-LLACLSitgKAPDIIILDEPTNNLDLQNIEILTNAIRDY----KGTLL 508
Cdd:cd03237 96 --KTEIAKPLQIEQILDREVPELSGGELQRVaIAACLS---KDADIYLLDEPSAYLDVEQRLMASKVIRRFaennEKTAF 170
|
....*
gi 639228517 509 VISHD 513
Cdd:cd03237 171 VVEHD 175
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
338-519 |
1.05e-17 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 86.19 E-value: 1.05e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-----ERADFNS-------VYI 405
Cdd:TIGR02857 322 LEFSGVSVAYPGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIavngvPLADADAdswrdqiAWV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 406 DQDYSMINHSLSV-IQQAESfnwlPLPEHEVKTILSR-----FL----FGKET-WDKSCSVLSGGERMRLLLACLSItgK 474
Cdd:TIGR02857 402 PQHPFLFAGTIAEnIRLARP----DASDAEIREALERagldeFVaalpQGLDTpIGEGGAGLSGGQAQRLALARAFL--R 475
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 639228517 475 APDIIILDEPTNNLDLQNIEILTNAIRDYKG--TLLVISHDDVFSEE 519
Cdd:TIGR02857 476 DAPLLLLDEPTAHLDAETEAEVLEALRALAQgrTVLLVTHRLALAAL 522
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
20-195 |
1.43e-17 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 82.69 E-value: 1.43e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpqileqfDTQSIARalgvqKKLSALREILEG 99
Cdd:cd03294 42 DVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQ-----------DIAAMSR-----KELRELRRKKIS 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 100 IVTEE-----NITVLDD-NWDLE----------EKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIILM 163
Cdd:cd03294 106 MVFQSfallpHRTVLENvAFGLEvqgvpraereERAAEALELVGLEGW-EHKYPDELSGGMQQRVGLARALAVDPDILLM 184
|
170 180 190
....*....|....*....|....*....|....*.
gi 639228517 164 DEPTNHLD----RQSREQLYEFIENTNKTLLVVSHD 195
Cdd:cd03294 185 DEAFSALDplirREMQDELLRLQAELQKTIVFITHD 220
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
19-195 |
1.45e-17 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 81.74 E-value: 1.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpQILEQ-------FDTQSIARALGVQKKLS 91
Cdd:TIGR01184 2 KGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGK-----QITEPgpdrmvvFQNYSLLPWLTVRENIA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 92 -ALREILEGIVTEENITVLDDNWDLEEkikqaletwglLDFTADESMNRLSGGQKTKVLIA-GIEIhQPDIILMDEPTNH 169
Cdd:TIGR01184 77 lAVDRVLPDLSKSERRAIVEEHIALVG-----------LTEAADKRPGQLSGGMKQRVAIArALSI-RPKVLLLDEPFGA 144
|
170 180 190
....*....|....*....|....*....|
gi 639228517 170 LDRQSR----EQLYEFIENTNKTLLVVSHD 195
Cdd:TIGR01184 145 LDALTRgnlqEELMQIWEEHRVTVLMVTHD 174
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
20-218 |
1.52e-17 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 81.79 E-value: 1.52e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFdtQSIARALGVQKKLSALRE---I 96
Cdd:PRK11629 27 NVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNG------QPMSKL--SSAAKAELRNQKLGFIYQfhhL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 97 LEGIVTEENIT--VLDDNWDLEEKIKQALETWGL--LDFTADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDR 172
Cdd:PRK11629 99 LPDFTALENVAmpLLIGKKKPAEINSRALEMLAAvgLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDA 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 639228517 173 QSREQLYEFIENTNK----TLLVVSHDRTLLNLLPKTAELS----RKEMMLYGG 218
Cdd:PRK11629 179 RNADSIFQLLGELNRlqgtAFLVVTHDLQLAKRMSRQLEMRdgrlTAELSLMGA 232
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
2-194 |
1.63e-17 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 81.45 E-value: 1.63e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQhpDKEILFEnLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqfdtQSIA 81
Cdd:TIGR01277 1 LALDKVRYE--YEHLPME-FDLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVND--------------QSHT 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGVQKKLSAL---REILEGIVTEENITV-----LDDNWDLEEKIKQALETWGLLDFTaDESMNRLSGGQKTKVLIAGI 153
Cdd:TIGR01277 64 GLAPYQRPVSMLfqeNNLFAHLTVRQNIGLglhpgLKLNAEQQEKVVDAAQQVGIADYL-DRLPEQLSGGQRQRVALARC 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 639228517 154 EIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSH 194
Cdd:TIGR01277 143 LVRPNPILLLDEPFSALDPLLREEMLALVkqlcSERQRTLLMVTH 187
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
1-274 |
1.68e-17 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 85.61 E-value: 1.68e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEIL-FENLNFIvnKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTegsvyylpqileqfdTQS 79
Cdd:PRK10636 312 LLKMEKVSAGYGDRIILdSIKLNLV--PGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL---------------AKG 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 80 IARALGVQKKLSALREILEGIvteENITVLDDNwDLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIHQPD 159
Cdd:PRK10636 375 IKLGYFAQHQLEFLRADESPL---QHLARLAPQ-ELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPN 450
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 160 IILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLLNllPKTAEL---SRKEMMLYGGNYDSYKE-----QKQIQQ 231
Cdd:PRK10636 451 LLLLDEPTNHLDLDMRQALTEALIDFEGALVVVSHDRHLLR--STTDDLylvHDGKVEPFDGDLEDYQQwlsdvQKQENQ 528
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 639228517 232 NALQNSIKNTENALKKAKATERETLERQQ-----KLDAKGKKKQEKAG 274
Cdd:PRK10636 529 TDEAPKENNANSAQARKDQKRREAELRTQtqplrKEIARLEKEMEKLN 576
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
338-514 |
1.81e-17 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 81.25 E-value: 1.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSV-------------- 403
Cdd:COG2884 2 IRFENVSKRYPGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSrlkrreipylrrri 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 404 -YIDQDYSMINHsLSVIQQAEsfnwLPL-----PEHEVKT----ILSRF-LFGKEtwDKSCSVLSGGERMRLLLAclsit 472
Cdd:COG2884 82 gVVFQDFRLLPD-RTVYENVA----LPLrvtgkSRKEIRRrvreVLDLVgLSDKA--KALPHELSGGEQQRVAIA----- 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 639228517 473 gKA----PDIIILDEPTNNLDLQN-IEILT--NAIRDYKGTLLVISHDD 514
Cdd:COG2884 150 -RAlvnrPELLLADEPTGNLDPETsWEIMEllEEINRRGTTVLIATHDL 197
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
20-194 |
1.88e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 82.76 E-value: 1.88e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPsagdirTEGSVyylpQILEQFDTQSIAralgvQKKLSALREILeG 99
Cdd:PRK13634 25 DVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQP------TSGTV----TIGERVITAGKK-----NKKLKPLRKKV-G 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 100 IVT--------EEniTVLDD------NW-----DLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIHQPDI 160
Cdd:PRK13634 89 IVFqfpehqlfEE--TVEKDicfgpmNFgvseeDAKQKAREMIELVGLPEELLARSPFELSGGQMRRVAIAGVLAMEPEV 166
|
170 180 190
....*....|....*....|....*....|....*...
gi 639228517 161 ILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSH 194
Cdd:PRK13634 167 LVLDEPTAGLDPKGRKEMMEMFYKLHKekglTTVLVTH 204
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
19-235 |
2.10e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 83.36 E-value: 2.10e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTE----GSVYYLPQILEQFDTQSIARALGVQKKLSAL- 93
Cdd:PRK13631 43 NNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGdiyiGDKKNNHELITNPYSKKIKNFKELRRRVSMVf 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 94 --------REILEGIVTEENITVLDDNWDLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIHQPDIILMDE 165
Cdd:PRK13631 123 qfpeyqlfKDTIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLDDSYLERSPFGLSGGQKRRVAIAGILAIQPEILIFDE 202
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 166 PTNHLDRQSREQLYEFIENT---NKTLLVVSHdrTLLNLLPKTAE---LSRKEMMLYGGNYDSYKEQKQIQQNALQ 235
Cdd:PRK13631 203 PTAGLDPKGEHEMMQLILDAkanNKTVFVITH--TMEHVLEVADEvivMDKGKILKTGTPYEIFTDQHIINSTSIQ 276
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
19-195 |
2.60e-17 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 82.83 E-value: 2.60e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLpqileqfDTQSIARALGV---QKK-----L 90
Cdd:COG4586 39 DDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYVPFK-------RRKEFARRIGVvfgQRSqlwwdL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 91 SA------LREILEgiVTE----ENITVLDDNWDLEEKIKQALetwglldftadesmNRLSGGQKTKVLIAGIEIHQPDI 160
Cdd:COG4586 112 PAidsfrlLKAIYR--IPDaeykKRLDELVELLDLGELLDTPV--------------RQLSLGQRMRCELAAALLHRPKI 175
|
170 180 190
....*....|....*....|....*....|....*....
gi 639228517 161 ILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHD 195
Cdd:COG4586 176 LFLDEPTIGLDVVSKEAIREFLKEYNRergtTILLTSHD 214
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
2-197 |
2.80e-17 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 80.76 E-value: 2.80e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS-VYYLP----QILEQFD 76
Cdd:cd03301 1 VELENVTKRFGNVTAL-DDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRdVTDLPpkdrDIAMVFQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 77 T----------QSIARALGVQKklsalreilegiVTEENItvlddnwdlEEKIKQALETWGLldftaDESMNR----LSG 142
Cdd:cd03301 80 NyalyphmtvyDNIAFGLKLRK------------VPKDEI---------DERVREVAELLQI-----EHLLDRkpkqLSG 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 143 GQKTKVLIAGIEIHQPDIILMDEPTNHLD----RQSREQLYEFIENTNKTLLVVSHDRT 197
Cdd:cd03301 134 GQRQRVALGRAIVREPKVFLMDEPLSNLDaklrVQMRAELKRLQQRLGTTTIYVTHDQV 192
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
1-195 |
3.24e-17 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 81.28 E-value: 3.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS-----------VYYLP 69
Cdd:PRK11248 1 MLQISHLYADYGGKPAL-EDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKpvegpgaergvVFQNE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 70 QILEQFDTQSIArALGVQkklsalreiLEGIVTEENitvlddnwdlEEKIKQALETWGLLDFTAdESMNRLSGGQKTKVL 149
Cdd:PRK11248 80 GLLPWRNVQDNV-AFGLQ---------LAGVEKMQR----------LEIAHQMLKKVGLEGAEK-RYIWQLSGGQRQRVG 138
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 639228517 150 IAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:PRK11248 139 IARALAANPQLLLLDEPFGALDAFTREQMQTLLlklwQETGKQVLLITHD 188
|
|
| F420-0_ABC_ATP |
TIGR03873 |
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ... |
32-198 |
3.28e-17 |
|
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ATP-binding protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and a permease (TIGR03869). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with a F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this ATP-binding protein is a component of an F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.
Pssm-ID: 163585 [Multi-domain] Cd Length: 256 Bit Score: 81.40 E-value: 3.28e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 32 AIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS-VYYLPQIleqfdtqsiARALGVqkklsALREilEGIVTEENITVLD 110
Cdd:TIGR03873 31 GLLGPNGSGKSTLLRLLAGALRPDAGTVDLAGVdLHGLSRR---------ARARRV-----ALVE--QDSDTAVPLTVRD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 111 ---------------DNWDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSR 175
Cdd:TIGR03873 95 vvalgriphrslwagDSPHDAAVVDRALARTELSHL-ADRDMSTLSGGERQRVHVARALAQEPKLLLLDEPTNHLDVRAQ 173
|
170 180
....*....|....*....|....*.
gi 639228517 176 EQLYEFIE---NTNKTLLVVSHDRTL 198
Cdd:TIGR03873 174 LETLALVRelaATGVTVVAALHDLNL 199
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
20-195 |
3.71e-17 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 80.24 E-value: 3.71e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAG-------DIRTE-----GSVYYLPqileQFDTqsiaralgvq 87
Cdd:cd03263 20 DLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGtayingySIRTDrkaarQSLGYCP----QFDA---------- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 88 kklsalreILEGIVTEENITVLD-----DNWDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIIL 162
Cdd:cd03263 86 --------LFDELTVREHLRFYArlkglPKSEIKEEVELLLRVLGLTDK-ANKRARTLSGGMKRKLSLAIALIGGPSVLL 156
|
170 180 190
....*....|....*....|....*....|....*
gi 639228517 163 MDEPTNHLDRQSREQLYEFI--ENTNKTLLVVSHD 195
Cdd:cd03263 157 LDEPTSGLDPASRRAIWDLIleVRKGRSIILTTHS 191
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
338-513 |
4.09e-17 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 84.43 E-value: 4.09e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWK-KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-------ERADFNSV-----Y 404
Cdd:COG4987 334 LELEDVSFRYPGAGRPVlDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSItlggvdlRDLDEDDLrrriaV 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 405 IDQDYSMINHSL-----------------SVIQQAESFNWLP-LPEhevktilsrflfGKETWdkscsV------LSGGE 460
Cdd:COG4987 414 VPQRPHLFDTTLrenlrlarpdatdeelwAALERVGLGDWLAaLPD------------GLDTW-----LgeggrrLSGGE 476
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 639228517 461 RMRLLLA--CLSitgkAPDIIILDEPTNNLDLQNIEILTNAIRDY-KG-TLLVISHD 513
Cdd:COG4987 477 RRRLALAraLLR----DAPILLLDEPTEGLDAATEQALLADLLEAlAGrTVLLITHR 529
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
25-202 |
5.71e-17 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 84.09 E-value: 5.71e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 25 VNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQ-ILEQFDTQsiaralgvqkklsaLREILEGIVTE 103
Cdd:PRK13409 362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELKISYKPQyIKPDYDGT--------------VEDLLRSITDD 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 104 enitvLDDNWDLEEKIKQ-ALETwgLLdftaDESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDrqsREQLYE-- 180
Cdd:PRK13409 428 -----LGSSYYKSEIIKPlQLER--LL----DKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD---VEQRLAva 493
|
170 180
....*....|....*....|....*..
gi 639228517 181 -----FIENTNKTLLVVSHDRTLLNLL 202
Cdd:PRK13409 494 kairrIAEEREATALVVDHDIYMIDYI 520
|
|
| NHLM_micro_ABC1 |
TIGR03796 |
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ... |
2-194 |
9.20e-17 |
|
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274788 [Multi-domain] Cd Length: 710 Bit Score: 83.45 E-value: 9.20e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQH-PDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSI 80
Cdd:TIGR03796 478 VELRNITFGYsPLEPPLIENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQPWSGEILFDG------IPREEIPREVL 551
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALG-VQKKLSalreILEGIVtEENITVlddnWD---LEEKIKQALETW----------GLLDFTADESMNRLSGGQKT 146
Cdd:TIGR03796 552 ANSVAmVDQDIF----LFEGTV-RDNLTL----WDptiPDADLVRACKDAaihdvitsrpGGYDAELAEGGANLSGGQRQ 622
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 147 KVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSH 194
Cdd:TIGR03796 623 RLEIARALVRNPSILILDEATSALDPETEKIIDDNLRRRGCTCIIVAH 670
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
20-194 |
1.97e-16 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 81.99 E-value: 1.97e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileQFDTQSIARALGVqkklsalreileG 99
Cdd:COG1129 22 GVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPV-------RFRSPRDAQAAGI------------A 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 100 IVTEE-----NITVLDD-------------NW-DLEEKIKQALETWGLlDFTADESMNRLSGGQKTKVLIAGIEIHQPDI 160
Cdd:COG1129 83 IIHQElnlvpNLSVAENiflgreprrggliDWrAMRRRARELLARLGL-DIDPDTPVGDLSVAQQQLVEIARALSRDARV 161
|
170 180 190
....*....|....*....|....*....|....*..
gi 639228517 161 ILMDEPTNHLDRQSREQLYEFIEN---TNKTLLVVSH 194
Cdd:COG1129 162 LILDEPTASLTEREVERLFRIIRRlkaQGVAIIYISH 198
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
338-512 |
3.21e-16 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 77.26 E-value: 3.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradFNSVYIDQDYSMINHSLS 417
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDD-ISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEIT---FDGKSYQKNIEALRRIGA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 418 VIQQAESFNWLP-------------LPEHEVKTILSRFLFgKETWDKSCSVLSGGERMRLLLAClSITGKaPDIIILDEP 484
Cdd:cd03268 77 LIEAPGFYPNLTarenlrllarllgIRKKRIDEVLDVVGL-KDSAKKKVKGFSLGMKQRLGIAL-ALLGN-PDLLILDEP 153
|
170 180 190
....*....|....*....|....*....|.
gi 639228517 485 TNNLDLQNIEILTNAIRDYK---GTLLVISH 512
Cdd:cd03268 154 TNGLDPDGIKELRELILSLRdqgITVLISSH 184
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
12-194 |
3.24e-16 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 77.97 E-value: 3.24e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 12 PDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIrtegsvyylpqileQFDTQSIaRALgvqkKLS 91
Cdd:cd03249 14 PDVPIL-KGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEI--------------LLDGVDI-RDL----NLR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 92 ALREILeGIVTEE----NITVLD-----DNWDLEEKIKQALETWGLLDFTAD----------ESMNRLSGGQKTKVLIAG 152
Cdd:cd03249 74 WLRSQI-GLVSQEpvlfDGTIAEnirygKPDATDEEVEEAAKKANIHDFIMSlpdgydtlvgERGSQLSGGQKQRIAIAR 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 639228517 153 IEIHQPDIILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSH 194
Cdd:cd03249 153 ALLRNPKILLLDEATSALDAESEKLVQEALDRamKGRTTIVIAH 196
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
338-528 |
3.32e-16 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 76.46 E-value: 3.32e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIwKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE-------RADFNSVYIDQDYS 410
Cdd:cd03229 1 LELKNVSKRYGQKTV-LNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILidgedltDLEDELPPLRRRIG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 411 MinhslsVIQQAESFNWLplpehevkTILSRFLFGketwdkscsvLSGGERMRLLLA-CLSITgkaPDIIILDEPTNNLD 489
Cdd:cd03229 80 M------VFQDFALFPHL--------TVLENIALG----------LSGGQQQRVALArALAMD---PDVLLLDEPTSALD 132
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 639228517 490 L---QNIEILTNAIRDYKG-TLLVISHDdvFSEEINIETRILL 528
Cdd:cd03229 133 PitrREVRALLKSLQAQLGiTVVLVTHD--LDEAARLADRVVV 173
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
5-194 |
3.53e-16 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 77.90 E-value: 3.53e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 5 QNITYQH---PDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG---SVY---YL------- 68
Cdd:cd03248 15 QNVTFAYptrPDTLVL-QDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGkpiSQYehkYLhskvslv 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 69 ---PQILEQFDTQSIARALGvQKKLSALREILEGIVTEENITVLDDNWDLEekikqaletwglldftADESMNRLSGGQK 145
Cdd:cd03248 94 gqePVLFARSLQDNIAYGLQ-SCSFECVKEAAQKAHAHSFISELASGYDTE----------------VGEKGSQLSGGQK 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE--NTNKTLLVVSH 194
Cdd:cd03248 157 QRVAIARALIRNPQVLILDEATSALDAESEQQVQQALYdwPERRTVLVIAH 207
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-194 |
4.07e-16 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 79.08 E-value: 4.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKeILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVyyLPQILEQfdtqsiA 81
Cdd:PRK13537 8 IDFRNVEKRYGDK-LVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEP--VPSRARH------A 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RA-LGVQKKLSALREileGIVTEENITVLDDNWDLEEKIKQALETwGLLDFT-----ADESMNRLSGGQKTKVLIAGIEI 155
Cdd:PRK13537 79 RQrVGVVPQFDNLDP---DFTVRENLLVFGRYFGLSAAAARALVP-PLLEFAklenkADAKVGELSGGMKRRLTLARALV 154
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 639228517 156 HQPDIILMDEPTNHLDRQSREQLYEFIEN---TNKTLLVVSH 194
Cdd:PRK13537 155 NDPDVLVLDEPTTGLDPQARHLMWERLRSllaRGKTILLTTH 196
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
4-195 |
4.08e-16 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 77.75 E-value: 4.08e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKEILFeNLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQILEQFDTQSIARA 83
Cdd:COG4161 5 LKNINCFYGSHQALF-DINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDFSQKPSEKAIRLLRQK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 84 LGV---QKKLSALREILEGIvTEENITVLDDN-WDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPD 159
Cdd:COG4161 84 VGMvfqQYNLWPHLTVMENL-IEAPCKVLGLSkEQAREKAMKLLARLRLTDK-ADRFPLHLSGGQQQRVAIARALMMEPQ 161
|
170 180 190
....*....|....*....|....*....|....*....
gi 639228517 160 IILMDEPTNHLDRQSREQLYEFIEN---TNKTLLVVSHD 195
Cdd:COG4161 162 VLLFDEPTAALDPEITAQVVEIIRElsqTGITQVIVTHE 200
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
1-195 |
4.22e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 78.60 E-value: 4.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHpDKEILFENLN---FIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDT 77
Cdd:PRK13642 4 ILEVENLVFKY-EKESDVNQLNgvsFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDG------ELLTAENV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 QSIARALGVQkkLSALREILEGIVTEENITVLDDNWDL--EEKIK---QALETWGLLDFTADESMnRLSGGQKTKVLIAG 152
Cdd:PRK13642 77 WNLRRKIGMV--FQNPDNQFVGATVEDDVAFGMENQGIprEEMIKrvdEALLAVNMLDFKTREPA-RLSGGQKQRVAVAG 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 639228517 153 IEIHQPDIILMDEPTNHLDRQSREQ----LYEFIENTNKTLLVVSHD 195
Cdd:PRK13642 154 IIALRPEIIILDESTSMLDPTGRQEimrvIHEIKEKYQLTVLSITHD 200
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
1-195 |
4.35e-16 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 78.74 E-value: 4.35e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRtegsvyylpqileqFDTQSI 80
Cdd:PRK13636 5 ILKVEELNYNYSDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRIL--------------FDGKPI 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARAlgvQKKLSALREILeGIVTEE------NITVLDD------NWDLEEK-----IKQALETWGLLDFTaDESMNRLSGG 143
Cdd:PRK13636 71 DYS---RKGLMKLRESV-GMVFQDpdnqlfSASVYQDvsfgavNLKLPEDevrkrVDNALKRTGIEHLK-DKPTHCLSFG 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 144 QKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHD 195
Cdd:PRK13636 146 QKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKelglTIIIATHD 201
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
355-512 |
1.30e-15 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 79.47 E-value: 1.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 355 KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIER-ADFNSVYIDQD-YsMINHSL-SVI---QQAESFnwl 428
Cdd:COG4178 380 EDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARpAGARVLFLPQRpY-LPLGTLrEALlypATAEAF--- 455
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 429 plPEHEVKTILSRF--------LFGKETWDKscsVLSGGERMRLLLACLSITgkAPDIIILDEPTNNLDLQNIEILTNAI 500
Cdd:COG4178 456 --SDAELREALEAVglghlaerLDEEADWDQ---VLSLGEQQRLAFARLLLH--KPDWLFLDEATSALDEENEAALYQLL 528
|
170
....*....|....
gi 639228517 501 RD--YKGTLLVISH 512
Cdd:COG4178 529 REelPGTTVISVGH 542
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
19-218 |
1.41e-15 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 77.79 E-value: 1.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAgdiRTEGSVYYLPQILEQFDTQSIARALGvqKK--------L 90
Cdd:COG0444 22 DGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPG---ITSGEILFDGEDLLKLSEKELRKIRG--REiqmifqdpM 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 91 SAL------REILE------GIVTEEnitvlddnwDLEEKIKQALETWGLLDftADESMNR----LSGGQKTKVLIA-GI 153
Cdd:COG0444 97 TSLnpvmtvGDQIAeplrihGGLSKA---------EARERAIELLERVGLPD--PERRLDRypheLSGGMRQRVMIArAL 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 154 eIHQPDIILMDEPTNHLD----RQSREQLYEFIENTNKTLLVVSHDrtlLNLLpktAELSRKEMMLYGG 218
Cdd:COG0444 166 -ALEPKLLIADEPTTALDvtiqAQILNLLKDLQRELGLAILFITHD---LGVV---AEIADRVAVMYAG 227
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
2-197 |
1.54e-15 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 77.84 E-value: 1.54e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHpDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS--------------VYy 67
Cdd:PRK11432 7 VVLKNITKRF-GSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEdvthrsiqqrdicmVF- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 68 lpQILEQFDTQSIARALGVQKKLsalreilEGIVTEEnitvlddnwdLEEKIKQALETWGLLDFtADESMNRLSGGQKTK 147
Cdd:PRK11432 85 --QSYALFPHMSLGENVGYGLKM-------LGVPKEE----------RKQRVKEALELVDLAGF-EDRYVDQISGGQQQR 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 639228517 148 VLIAGIEIHQPDIILMDEPTNHLD----RQSREQLYEFIENTNKTLLVVSHDRT 197
Cdd:PRK11432 145 VALARALILKPKVLLFDEPLSNLDanlrRSMREKIRELQQQFNITSLYVTHDQS 198
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
355-512 |
1.66e-15 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 74.11 E-value: 1.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 355 KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIER-ADFNSVYIDQDYSMINHSLsviqqaesfnwlplpeh 433
Cdd:cd03223 18 KDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMpEGEDLLFLPQRPYLPLGTL----------------- 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 434 evKTILSRflfgkeTWDKscsVLSGGERMRLLLACLSITGkaPDIIILDEPTNNLDLQNIEILTNAIRDYKGTLLVISH 512
Cdd:cd03223 81 --REQLIY------PWDD---VLSGGEQQRLAFARLLLHK--PKFVFLDEATSALDEESEDRLYQLLKELGITVISVGH 146
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
19-235 |
1.72e-15 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 77.43 E-value: 1.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDI------------RTEGSVYYLPQILEQFDTQSIARALGV 86
Cdd:PRK13651 24 DNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewifkdeknkkkTKEKEKVLEKLVIQKTRFKKIKKIKEI 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 87 QKKLSALREILEGIVTEEniTVLDD-----------NWDLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEI 155
Cdd:PRK13651 104 RRRVGVVFQFAEYQLFEQ--TIEKDiifgpvsmgvsKEEAKKRAAKYIELVGLDESYLQRSPFELSGGQKRRVALAGILA 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 156 HQPDIILMDEPTNHLDRQSREQLYEFIENTN---KTLLVVSHDrtLLNLLPKTAE---LSRKEMMLYGGNYDSYKEQKQI 229
Cdd:PRK13651 182 MEPDFLVFDEPTAGLDPQGVKEILEIFDNLNkqgKTIILVTHD--LDNVLEWTKRtifFKDGKIIKDGDTYDILSDNKFL 259
|
....*.
gi 639228517 230 QQNALQ 235
Cdd:PRK13651 260 IENNME 265
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
2-217 |
1.94e-15 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 75.01 E-value: 1.94e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS---------VYYLP--- 69
Cdd:cd03269 1 LEVENVTKRFGRVTAL-DDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKpldiaarnrIGYLPeer 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 70 ------QILEQFdtQSIARALGVQKKlSALREILEGIvteenitvldDNWDLEEKIKQALETwglldftadesmnrLSGG 143
Cdd:cd03269 80 glypkmKVIDQL--VYLAQLKGLKKE-EARRRIDEWL----------ERLELSEYANKRVEE--------------LSKG 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 144 QKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI---ENTNKTLLVVSH---------DRTLLnllpktaeLSRK 211
Cdd:cd03269 133 NQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKDVIrelARAGKTVILSTHqmelveelcDRVLL--------LNKG 204
|
....*.
gi 639228517 212 EMMLYG 217
Cdd:cd03269 205 RAVLYG 210
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
2-196 |
2.03e-15 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 77.49 E-value: 2.03e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqilEQFDTQSIA 81
Cdd:COG1118 3 IEVRNISKRFGSFTLL-DDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNG---------RDLFTNLPP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGVqkklsalreileGIV----------T-EENI----TVLD-DNWDLEEKIKQALETWGLLDFtADESMNRLSGGQK 145
Cdd:COG1118 73 RERRV------------GFVfqhyalfphmTvAENIafglRVRPpSKAEIRARVEELLELVQLEGL-ADRYPSQLSGGQR 139
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLY----EFIENTNKTLLVVSHDR 196
Cdd:COG1118 140 QRVALARALAVEPEVLLLDEPFGALDAKVRKELRrwlrRLHDELGGTTVFVTHDQ 194
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
2-192 |
2.05e-15 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 75.55 E-value: 2.05e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFeNLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG-SVYYLPqileqfdTQSI 80
Cdd:cd03224 1 LEVENLNAGYGKSQILF-GVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGrDITGLP-------PHER 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARAlGVqkklsAL----REILEGIVTEENITV---LDDNWDLEEKIKQALETWGLLDftadESMNR----LSGGQKTKVL 149
Cdd:cd03224 73 ARA-GI-----GYvpegRRIFPELTVEENLLLgayARRRAKRKARLERVYELFPRLK----ERRKQlagtLSGGEQQMLA 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 639228517 150 IAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK---TLLVV 192
Cdd:cd03224 143 IARALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDegvTILLV 188
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
7-199 |
2.13e-15 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 75.30 E-value: 2.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 7 ITYQHPDKEIL-----FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG---------SVYYLP-QI 71
Cdd:PRK10908 2 IRFEHVSKAYLggrqaLQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGhditrlknrEVPFLRrQI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 72 LEQFDTQSIARALGVQKKLsALREILEGIVTEenitvlddnwDLEEKIKQALETWGLLDfTADESMNRLSGGQKTKVLIA 151
Cdd:PRK10908 82 GMIFQDHHLLMDRTVYDNV-AIPLIIAGASGD----------DIRRRVSAALDKVGLLD-KAKNFPIQLSGGEQQRVGIA 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 152 GIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK---TLLVVSHDRTLL 199
Cdd:PRK10908 150 RAVVNKPAVLLADEPTGNLDDALSEGILRLFEEFNRvgvTVLMATHDIGLI 200
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
12-194 |
2.42e-15 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 78.73 E-value: 2.42e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 12 PDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLtPSAGDIRTEGsvyylpQILEQFDTQSIaralgvQKKLS 91
Cdd:PRK11174 360 PDGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSLKING------IELRELDPESW------RKHLS 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 92 ALRE---ILEGIVtEENITVLDDNWDlEEKIKQALETWGLLDFTAD----------ESMNRLSGGQKTKVLIAGIEIHQP 158
Cdd:PRK11174 427 WVGQnpqLPHGTL-RDNVLLGNPDAS-DEQLQQALENAWVSEFLPLlpqgldtpigDQAAGLSVGQAQRLALARALLQPC 504
|
170 180 190
....*....|....*....|....*....|....*...
gi 639228517 159 DIILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSH 194
Cdd:PRK11174 505 QLLLLDEPTASLDAHSEQLVMQALNAasRRQTTLMVTH 542
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
1-196 |
2.52e-15 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 75.14 E-value: 2.52e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVY--YLPQILEQfdtq 78
Cdd:PRK10247 7 LLQLQNVGYLAGDAKIL-NNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDIstLKPEIYRQ---- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 siaralgvQKKLSALREILEGIVTEENITVlddNWDL------EEKIKQALETWGLLDFTADESMNRLSGGQKTKV-LIA 151
Cdd:PRK10247 82 --------QVSYCAQTPTLFGDTVYDNLIF---PWQIrnqqpdPAIFLDDLERFALPDTILTKNIAELSGGEKQRIsLIR 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 639228517 152 GIEIhQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHDR 196
Cdd:PRK10247 151 NLQF-MPKVLLLDEITSALDESNKHNVNEIIHRYVReqniAVLWVTHDK 198
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
338-513 |
2.74e-15 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 74.82 E-value: 2.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERaDFNSV--------YID 406
Cdd:cd03293 1 LEVRNVSKTYGGGGGAVTALEDIslsVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLV-DGEPVtgpgpdrgYVF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 407 QDYSMINHsLSVIQQAEsfnwLPL-----PEHEVKTILSRFL--FG-KETWDKSCSVLSGGERMRLLLA-CLSITgkaPD 477
Cdd:cd03293 80 QQDALLPW-LTVLDNVA----LGLelqgvPKAEARERAEELLelVGlSGFENAYPHQLSGGMRQRVALArALAVD---PD 151
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 639228517 478 IIILDEPTNNLD------LQniEILTNAIRDYKGTLLVISHD 513
Cdd:cd03293 152 VLLLDEPFSALDaltreqLQ--EELLDIWRETGKTVLLVTHD 191
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-195 |
2.83e-15 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 75.56 E-value: 2.83e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTeGSVyylpqileQFDTqsi 80
Cdd:PRK11264 3 AIEVKNLVKKFHGQTVL-HGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRV-GDI--------TIDT--- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKKL---------------------SALREILEG--IVTEEnitvlddnwDLEEKIKQALETWGLLDFTADESM 137
Cdd:PRK11264 70 ARSLSQQKGLirqlrqhvgfvfqnfnlfphrTVLENIIEGpvIVKGE---------PKEEATARARELLAKVGLAGKETS 140
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639228517 138 --NRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHD 195
Cdd:PRK11264 141 ypRRLSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRqlaQEKRTMVIVTHE 203
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
5-228 |
3.65e-15 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 78.05 E-value: 3.65e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 5 QNITYQHPDKeILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVY--YLPQILEQFDTQSiar 82
Cdd:TIGR03719 326 ENLTKAFGDK-LLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIGETVKlaYVDQSRDALDPNK--- 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 83 algvqkklSALREILEGivteenitvlDDNWDLEEKIKQALETWGLLDFTADESMNR---LSGGQKTKVLIAGIEIHQPD 159
Cdd:TIGR03719 402 --------TVWEEISGG----------LDIIKLGKREIPSRAYVGRFNFKGSDQQKKvgqLSGGERNRVHLAKTLKSGGN 463
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639228517 160 IILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTLLNLLpKTAELS---RKEMMLYGGNYDSYKEQKQ 228
Cdd:TIGR03719 464 VLLLDEPTNDLDVETLRALEEALLNFAGCAVVISHDRWFLDRI-ATHILAfegDSHVEWFEGNFSEYEEDKK 534
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
8-195 |
3.74e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 75.97 E-value: 3.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 8 TYQH--PDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpQILEQFDTQSIARalg 85
Cdd:PRK13646 11 TYQKgtPYEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDI-----TITHKTKDKYIRP--- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 86 VQKKLSALREILEGIVTEENIT------VLDDNWDLEEKIKQALETWGLLDFTAD---ESMNRLSGGQKTKVLIAGIEIH 156
Cdd:PRK13646 83 VRKRIGMVFQFPESQLFEDTVEreiifgPKNFKMNLDEVKNYAHRLLMDLGFSRDvmsQSPFQMSGGQMRKIAIVSILAM 162
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 639228517 157 QPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:PRK13646 163 NPDIIVLDEPTAGLDPQSKRQVMRLLkslqTDENKTIILVSHD 205
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-208 |
4.10e-15 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 75.15 E-value: 4.10e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS--VYYLPQILeQFDTQ 78
Cdd:PRK09544 4 LVSLENVSVSFGQRRVL-SDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKlrIGYVPQKL-YLDTT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 ---SIARAL----GVQKK--LSALREIlegivteenitvlddnwdleekikQALEtwgLLDFtadeSMNRLSGGQKTKVL 149
Cdd:PRK09544 82 lplTVNRFLrlrpGTKKEdiLPALKRV------------------------QAGH---LIDA----PMQKLSGGETQRVL 130
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639228517 150 IAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTL----LVVSHDRTLlnLLPKTAEL 208
Cdd:PRK09544 131 LARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELdcavLMVSHDLHL--VMAKTDEV 191
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
337-528 |
4.33e-15 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 75.12 E-value: 4.33e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGtieradfNSVYI-DQDY------ 409
Cdd:COG1119 3 LLELRNVTVRRGGKTILDD-ISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYG-------NDVRLfGERRggedvw 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 410 ---SMINHSLSVIQQAesfnwlpLPEHEV--KTILSRF-----LFGKETW-------------------DKSCSVLSGGE 460
Cdd:COG1119 75 elrKRIGLVSPALQLR-------FPRDETvlDVVLSGFfdsigLYREPTDeqrerarellellglahlaDRPFGTLSQGE 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 461 RMRLLLA-CLSitgKAPDIIILDEPTNNLDLQNIEILTNAIRDYKG----TLLVISHddvFSEEI--NIETRILL 528
Cdd:COG1119 148 QRRVLIArALV---KDPELLILDEPTAGLDLGARELLLALLDKLAAegapTLVLVTH---HVEEIppGITHVLLL 216
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
337-513 |
5.44e-15 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 74.63 E-value: 5.44e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE--RADFNSVYIDQDYSMINH 414
Cdd:COG1127 5 MIEVRNLTKSFGDRVVLDG-VSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILvdGQDITGLSEKELYELRRR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 415 ------------SLSVIQQAEsfnwLPLPEHE----------VKTILSrfLFG-KETWDKSCSVLSGGERMRLLLAclsi 471
Cdd:COG1127 84 igmlfqggalfdSLTVFENVA----FPLREHTdlseaeirelVLEKLE--LVGlPGAADKMPSELSGGMRKRVALA---- 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 639228517 472 tgKA----PDIIILDEPTNNLD---LQNIEILTNAIRD-YKGTLLVISHD 513
Cdd:COG1127 154 --RAlaldPEILLYDEPTAGLDpitSAVIDELIRELRDeLGLTSVVVTHD 201
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
32-195 |
6.14e-15 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 76.30 E-value: 6.14e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 32 AIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVY-----------------YLPQILEQFDTQSIARAL--GVQKKLSA 92
Cdd:TIGR02142 27 AIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLfdsrkgiflppekrrigYVFQEARLFPHLSVRGNLryGMKRARPS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 93 LREILEgivteenitvlddnwdleEKIKQALETWGLLDftadESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDR 172
Cdd:TIGR02142 107 ERRISF------------------ERVIELLGIGHLLG----RLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDD 164
|
170 180
....*....|....*....|....*..
gi 639228517 173 QSREQLYEFIEN----TNKTLLVVSHD 195
Cdd:TIGR02142 165 PRKYEILPYLERlhaeFGIPILYVSHS 191
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
337-512 |
6.79e-15 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 73.94 E-value: 6.79e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVY--------- 404
Cdd:cd03266 1 MITADALTKRFRDVKKTVQAVDGVsftVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKepaearrrl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 405 -IDQDYSMINHSLSVIQQAESFNWL-PLPEHE----VKTILSRFLFgKETWDKSCSVLSGGERMRLLLACLSItgKAPDI 478
Cdd:cd03266 81 gFVSDSTGLYDRLTARENLEYFAGLyGLKGDEltarLEELADRLGM-EELLDRRVGGFSTGMRQKVAIARALV--HDPPV 157
|
170 180 190
....*....|....*....|....*....|....*..
gi 639228517 479 IILDEPTNNLDLQNIEILTNAIRDYKG---TLLVISH 512
Cdd:cd03266 158 LLLDEPTTGLDVMATRALREFIRQLRAlgkCILFSTH 194
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
338-513 |
6.92e-15 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 74.08 E-value: 6.92e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-----ERADFNSvyiDQDYSMI 412
Cdd:cd03261 1 IELRGLTKSFGGRTVLKG-VDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVlidgeDISGLSE---AELYRLR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 413 NHSLSVIQQAESFNWL--------PLPEHE----------VKTILSRF-LFGKEtwDKSCSVLSGGERMRLLLAclsitg 473
Cdd:cd03261 77 RRMGMLFQSGALFDSLtvfenvafPLREHTrlseeeireiVLEKLEAVgLRGAE--DLYPAELSGGMKKRVALA------ 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 474 KA----PDIIILDEPTNNLDLQNIEILTNAIRDYKGTL----LVISHD 513
Cdd:cd03261 149 RAlaldPELLLYDEPTAGLDPIASGVIDDLIRSLKKELgltsIMVTHD 196
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-201 |
7.22e-15 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 76.42 E-value: 7.22e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG-------------SVYY 67
Cdd:PRK09536 3 MIDVSDLSVEFGDTTVL-DGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGddvealsaraasrRVAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 68 LPQ---ILEQFDTQSIARaLGVQKKLSALreileGIVTEENITVLDdnwdleekikQALETWGLLDFtADESMNRLSGGQ 144
Cdd:PRK09536 82 VPQdtsLSFEFDVRQVVE-MGRTPHRSRF-----DTWTETDRAAVE----------RAMERTGVAQF-ADRPVTSLSGGE 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLD--RQSR--EQLYEFIEnTNKTLLVVSHDrtlLNL 201
Cdd:PRK09536 145 RQRVLLARALAQATPVLLLDEPTASLDinHQVRtlELVRRLVD-DGKTAVAAIHD---LDL 201
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
4-194 |
1.25e-14 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 75.25 E-value: 1.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKeILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqilEQFDTQS-IAR 82
Cdd:PRK13536 44 LAGVSKSYGDK-AVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLG---------VPVPARArLAR 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 83 A-LGVQKKLSALReiLEGIVtEENITVLDDNW-----DLEEKIKQALEtWGLLDFTADESMNRLSGGQKTKVLIAGIEIH 156
Cdd:PRK13536 114 ArIGVVPQFDNLD--LEFTV-RENLLVFGRYFgmstrEIEAVIPSLLE-FARLESKADARVSDLSGGMKRRLTLARALIN 189
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 639228517 157 QPDIILMDEPTNHLDRQSREQLYEFIEN---TNKTLLVVSH 194
Cdd:PRK13536 190 DPQLLILDEPTTGLDPHARHLIWERLRSllaRGKTILLTTH 230
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
33-196 |
1.52e-14 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 74.84 E-value: 1.52e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 33 IVGNNGSGKSTLLKLISGLLTPSAGDIRTEG-SVYYLPQILeqfdtqsiaRALGVQKKLSALreiLEGIVTEENITV--- 108
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGeDVTNVPPHL---------RHINMVFQSYAL---FPHMTVEENVAFglk 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 109 --LDDNWDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQ----LYEFI 182
Cdd:TIGR01187 69 mrKVPRAEIKPRVLEALRLVQLEEF-ADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQmqleLKTIQ 147
|
170
....*....|....
gi 639228517 183 ENTNKTLLVVSHDR 196
Cdd:TIGR01187 148 EQLGITFVFVTHDQ 161
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
361-512 |
1.53e-14 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 72.62 E-value: 1.53e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGtieradfnSVYIDQ-DYSMINHS-LS-----VIQQAESFN------- 426
Cdd:cd03245 27 IRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSG--------SVLLDGtDIRQLDPAdLRrnigyVPQDVTLFYgtlrdni 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 427 WLPLPEHEVKTIL--SRFL------------FGKETWDKSCSvLSGGERMRLLLACLSItgKAPDIIILDEPTNNLDLQN 492
Cdd:cd03245 99 TLGAPLADDERILraAELAgvtdfvnkhpngLDLQIGERGRG-LSGGQRQAVALARALL--NDPPILLLDEPTSAMDMNS 175
|
170 180
....*....|....*....|..
gi 639228517 493 IEILTNAIRDYKG--TLLVISH 512
Cdd:cd03245 176 EERLKERLRQLLGdkTLIIITH 197
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
338-512 |
1.66e-14 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 71.58 E-value: 1.66e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWK-KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradFNSVYIDQDYSMINHSL 416
Cdd:cd03247 1 LSINNVSFSYPEQEQQVlKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEIT---LDGVPVSDLEKALSSLI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 417 SVIQQAEsfnwlplpehevktilsrFLFGKETWDKSCSVLSGGERMRLLLAclSITGKAPDIIILDEPTNNLD----LQN 492
Cdd:cd03247 78 SVLNQRP------------------YLFDTTLRNNLGRRFSGGERQRLALA--RILLQDAPIVLLDEPTVGLDpiteRQL 137
|
170 180
....*....|....*....|
gi 639228517 493 IEILTNAIRDykGTLLVISH 512
Cdd:cd03247 138 LSLIFEVLKD--KTLIWITH 155
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
357-514 |
2.14e-14 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 72.30 E-value: 2.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMK--PSEGTIERADFNsvyIDQDYSMINHslsvIQQAESFNwlplpehE 434
Cdd:COG2401 49 LNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKgtPVAGCVDVPDNQ---FGREASLIDA----IGRKGDFK-------D 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 435 VKTILSR------FLfgketWDKSCSVLSGGERMRLLLAcLSITGKaPDIIILDEPTNNLDLQNIEILTNAI----RDYK 504
Cdd:COG2401 115 AVELLNAvglsdaVL-----WLRRFKELSTGQKFRFRLA-LLLAER-PKLLVIDEFCSHLDRQTAKRVARNLqklaRRAG 187
|
170
....*....|
gi 639228517 505 GTLLVISHDD 514
Cdd:COG2401 188 ITLVVATHHY 197
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
2-196 |
2.20e-14 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 74.60 E-value: 2.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG-SVYYLPQILEQFDT--Q 78
Cdd:PRK09452 15 VELRGISKSFDGKEVI-SNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGqDITHVPAENRHVNTvfQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 S------------IARALGVQKklsalreilegiVTEENItvlddnwdlEEKIKQALETWGLLDFtADESMNRLSGGQKT 146
Cdd:PRK09452 94 SyalfphmtvfenVAFGLRMQK------------TPAAEI---------TPRVMEALRMVQLEEF-AQRKPHQLSGGQQQ 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 639228517 147 KVLIAGIEIHQPDIILMDEPTNHLDRQSREQ----LYEFIENTNKTLLVVSHDR 196
Cdd:PRK09452 152 RVAIARAVVNKPKVLLLDESLSALDYKLRKQmqneLKALQRKLGITFVFVTHDQ 205
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
2-194 |
2.30e-14 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 71.81 E-value: 2.30e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHP------DKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSagdiRTEGSVYYlpqileqf 75
Cdd:cd03213 4 LSFRNLTVTVKsspsksGKQLL-KNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGL----GVSGEVLI-------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 76 dtqsiaraLGVQKKLSALREILeGIVTEENI-----TVlddnwdleekikqaLETwglLDFTAdeSMNRLSGGQKTKVLI 150
Cdd:cd03213 71 --------NGRPLDKRSFRKII-GYVPQDDIlhptlTV--------------RET---LMFAA--KLRGLSGGERKRVSI 122
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 151 aGIE-IHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSH 194
Cdd:cd03213 123 -ALElVSNPSLLFLDEPTSGLDSSSALQVMSLLRrlaDTGRTIICSIH 169
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
2-195 |
2.98e-14 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 72.37 E-value: 2.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDI--------------RTEGSV-- 65
Cdd:cd03296 3 IEVRNVSKRFGDFVAL-DDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTIlfggedatdvpvqeRNVGFVfq 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 66 -YYLPQILEQFDtqSIARALGVQKKLSALREIlegivteenitvlddnwDLEEKIKQALETWGlLDFTADESMNRLSGGQ 144
Cdd:cd03296 82 hYALFRHMTVFD--NVAFGLRVKPRSERPPEA-----------------EIRAKVHELLKLVQ-LDWLADRYPAQLSGGQ 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHD 195
Cdd:cd03296 142 RQRVALARALAVEPKVLLLDEPFGALDAKVRKELRRWLrrlhDELHVTTVFVTHD 196
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
358-516 |
3.61e-14 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 70.15 E-value: 3.61e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 358 DVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI----ERADFNSVyidqdYSMINHSLSVIQQaesfnwlplpeh 433
Cdd:cd03216 20 SLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEIlvdgKEVSFASP-----RDARRAGIAMVYQ------------ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 434 evktilsrflfgketwdkscsvLSGGERMRLLLAclsitgKA----PDIIILDEPTNNLDLQNIEILTNAIRDYKG---T 506
Cdd:cd03216 83 ----------------------LSVGERQMVEIA------RAlarnARLLILDEPTAALTPAEVERLFKVIRRLRAqgvA 134
|
170
....*....|..
gi 639228517 507 LLVISH--DDVF 516
Cdd:cd03216 135 VIFISHrlDEVF 146
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
19-194 |
3.84e-14 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 71.76 E-value: 3.84e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqFDTQSIAralgvqkkLSALREILe 98
Cdd:cd03244 21 KNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDG-----------VDISKIG--------LHDLRSRI- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 99 GIVTEENI----TV---LD--DNWDlEEKIKQALETWGL----------LDFTADESMNRLSGGQKTKVLIAGIEIHQPD 159
Cdd:cd03244 81 SIIPQDPVlfsgTIrsnLDpfGEYS-DEELWQALERVGLkefveslpggLDTVVEEGGENLSVGQRQLLCLARALLRKSK 159
|
170 180 190
....*....|....*....|....*....|....*..
gi 639228517 160 IILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSH 194
Cdd:cd03244 160 ILVLDEATASVDPETDALIQKTIREafKDCTVLTIAH 196
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
355-513 |
5.74e-14 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 71.59 E-value: 5.74e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 355 KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSvYIDQDYSMINHSLSVIQQ---------AESF 425
Cdd:cd03267 38 KGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVP-WKRRKKFLRRIGVVFGQKtqlwwdlpvIDSF 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 426 NWLP----LPEHEVKTILSRF---LFGKETWDKSCSVLSGGERMRLLLACLSItgKAPDIIILDEPTNNLDL---QNI-E 494
Cdd:cd03267 117 YLLAaiydLPPARFKKRLDELselLDLEELLDTPVRQLSLGQRMRAEIAAALL--HEPEILFLDEPTIGLDVvaqENIrN 194
|
170
....*....|....*....
gi 639228517 495 ILTNAIRDYKGTLLVISHD 513
Cdd:cd03267 195 FLKEYNRERGTTVLLTSHY 213
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
20-195 |
5.90e-14 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 71.69 E-value: 5.90e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPsagdirTEGSVYYLPQILEQFDTQSIARaLGVQKKL---SALrei 96
Cdd:COG4674 28 DLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRP------DSGSVLFGGTDLTGLDEHEIAR-LGIGRKFqkpTVF--- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 97 legivteENITVLDdNWDL--------------------EEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIH 156
Cdd:COG4674 98 -------EELTVFE-NLELalkgdrgvfaslfarltaeeRDRIEEVLETIGLTDK-ADRLAGLLSHGQKQWLEIGMLLAQ 168
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 639228517 157 QPDIILMDEPTNHLDRQSREQLYEFIENTNK--TLLVVSHD 195
Cdd:COG4674 169 DPKLLLLDEPVAGMTDAETERTAELLKSLAGkhSVVVVEHD 209
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
20-194 |
7.19e-14 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 70.60 E-value: 7.19e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVN--KGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQILEQfDTQSIARALGVQKKLSALREIL 97
Cdd:cd03298 14 PMHFDLTfaQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADR-PVSMLFQENNLFAHLTVEQNVG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 98 EGIVTEENITVLDdnwdlEEKIKQALETWGLldftaDESMNR----LSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQ 173
Cdd:cd03298 93 LGLSPGLKLTAED-----RQAIEVALARVGL-----AGLEKRlpgeLSGGERQRVALARVLVRDKPVLLLDEPFAALDPA 162
|
170 180
....*....|....*....|....*
gi 639228517 174 SREQLYEFI----ENTNKTLLVVSH 194
Cdd:cd03298 163 LRAEMLDLVldlhAETKMTVLMVTH 187
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
5-194 |
9.35e-14 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 73.84 E-value: 9.35e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 5 QNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSIARAL 84
Cdd:PRK13657 338 DDVSFSYDNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDG------TDIRTVTRASLRRNI 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 85 GV--QKKLSALREILEGI-VTEENITvlddnwdlEEKIKQALETWGLLDFTADESM----------NRLSGGQKTKVLIA 151
Cdd:PRK13657 412 AVvfQDAGLFNRSIEDNIrVGRPDAT--------DEEMRAAAERAQAHDFIERKPDgydtvvgergRQLSGGERQRLAIA 483
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 639228517 152 GIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSH 194
Cdd:PRK13657 484 RALLKDPPILILDEATSALDVETEAKVKAALDElmKGRTTFIIAH 528
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-232 |
1.32e-13 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 70.57 E-value: 1.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLIS--GLLTPS---AGDIRTEGSVYYLPQIleqf 75
Cdd:PRK14239 5 ILQVSDLSVYYNKKKAL-NSVSLDFYPNEITALIGPSGSGKSTLLRSINrmNDLNPEvtiTGSIVYNGHNIYSPRT---- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 76 DTQSIARALGV--QKKLSALREILEGIVTEENITVLDDNWDLEEKIKQALETWGLLDFTAD---ESMNRLSGGQKTKVLI 150
Cdd:PRK14239 80 DTVDLRKEIGMvfQQPNPFPMSIYENVVYGLRLKGIKDKQVLDEAVEKSLKGASIWDEVKDrlhDSALGLSGGQQQRVCI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 151 AGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK--TLLVVSHDrtllnlLPKTAELSRKEMMLYGGNYDSYKEQKQ 228
Cdd:PRK14239 160 ARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDdyTMLLVTRS------MQQASRISDRTGFFLDGDLIEYNDTKQ 233
|
....
gi 639228517 229 IQQN 232
Cdd:PRK14239 234 MFMN 237
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-195 |
1.32e-13 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 70.89 E-value: 1.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNIT---YQH-PDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG-SVYYLP------ 69
Cdd:COG1101 1 MLELKNLSktfNPGtVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGkDVTKLPeykrak 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 70 -----------------QILEQFdtqSIARA--------LGVQKKLSAL-REILEGIvteenitvlddNWDLEEKIKQAl 123
Cdd:COG1101 81 yigrvfqdpmmgtapsmTIEENL---ALAYRrgkrrglrRGLTKKRRELfRELLATL-----------GLGLENRLDTK- 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 124 etwglldftadesMNRLSGGQKTKV--LIAGieIHQPDIILMDEPTNHLDRQSREQLYE----FIENTNKTLLVVSHD 195
Cdd:COG1101 146 -------------VGLLSGGQRQALslLMAT--LTKPKLLLLDEHTAALDPKTAALVLEltekIVEENNLTTLMVTHN 208
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
337-515 |
1.35e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 71.30 E-value: 1.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKK----PLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADF--NSVYIDQDYS 410
Cdd:PRK13643 1 MIKFEKVNYTYQPNSPFASralfDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIvvSSTSKQKEIK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 411 MINHSLSVIQQaesfnwlpLPEHEV--KTILSRFLFG-------------------------KETWDKSCSVLSGGERMR 463
Cdd:PRK13643 81 PVRKKVGVVFQ--------FPESQLfeETVLKDVAFGpqnfgipkekaekiaaeklemvglaDEFWEKSPFELSGGQMRR 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 639228517 464 LLLAclSITGKAPDIIILDEPTNNLDLQ-NIEI--LTNAIRDYKGTLLVISH--DDV 515
Cdd:PRK13643 153 VAIA--GILAMEPEVLVLDEPTAGLDPKaRIEMmqLFESIHQSGQTVVLVTHlmDDV 207
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
364-516 |
1.41e-13 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 73.23 E-value: 1.41e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 364 GERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSV-YIDQDySMINHSLSVIQQAEsfnwlplpE--HEVKTILS 440
Cdd:PRK11819 33 GAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPAPGIKVgYLPQE-PQLDPEKTVRENVE--------EgvAEVKAALD 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 441 RF-----LFGKET----------------------------------------WDKSCSVLSGGERMR-----LLLacls 470
Cdd:PRK11819 104 RFneiyaAYAEPDadfdalaaeqgelqeiidaadawdldsqleiamdalrcppWDAKVTKLSGGERRRvalcrLLL---- 179
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 639228517 471 itgKAPDIIILDEPTNNLDLQNIEILTNAIRDYKGTLLVISHDDVF 516
Cdd:PRK11819 180 ---EKPDMLLLDEPTNHLDAESVAWLEQFLHDYPGTVVAVTHDRYF 222
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
2-194 |
1.48e-13 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 69.42 E-value: 1.48e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEI----LFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQ------- 70
Cdd:cd03250 1 ISVEDASFTWDSGEQetsfTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGSIAYVSQepwiqng 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 71 -----IL--EQFDTQSIARALgvqkKLSALR---EILE-GIVTE--EN-ITvlddnwdleekikqaletwglldftades 136
Cdd:cd03250 81 tirenILfgKPFDEERYEKVI----KACALEpdlEILPdGDLTEigEKgIN----------------------------- 127
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639228517 137 mnrLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYE-----FIENtNKTLLVVSH 194
Cdd:cd03250 128 ---LSGGQKQRISLARAVYSDADIYLLDDPLSAVDAHVGRHIFEncilgLLLN-NKTRILVTH 186
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
334-513 |
1.52e-13 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 73.16 E-value: 1.52e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 334 GKILIKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQDYSMIN 413
Cdd:TIGR02868 331 GKPTLELRDLSAGYPGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRR 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 414 HSLsVIQQAESF-----NWLPL-----PEHEVKTILSR---------FLFGKETW-DKSCSVLSGGERMRLLLACLSITG 473
Cdd:TIGR02868 411 VSV-CAQDAHLFdttvrENLRLarpdaTDEELWAALERvgladwlraLPDGLDTVlGEGGARLSGGERQRLALARALLAD 489
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 639228517 474 kaPDIIILDEPTNNLDLQNIEILTNAIRDYKG--TLLVISHD 513
Cdd:TIGR02868 490 --APILLLDEPTEHLDAETADELLEDLLAALSgrTVVLITHH 529
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
360-512 |
1.74e-13 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 72.77 E-value: 1.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 360 VVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE--RADFNSV----------YIDQDYSMInhSLSVIQQAESFNW 427
Cdd:TIGR01842 340 SLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRldGADLKQWdretfgkhigYLPQDVELF--PGTVAENIARFGE 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 428 LPLPE-----------HEVktILsRFLFGKETW-DKSCSVLSGGERMRLLLAcLSITGkAPDIIILDEPTNNLDLQNIEI 495
Cdd:TIGR01842 418 NADPEkiieaaklagvHEL--IL-RLPDGYDTViGPGGATLSGGQRQRIALA-RALYG-DPKLVVLDEPNSNLDEEGEQA 492
|
170 180
....*....|....*....|
gi 639228517 496 LTNAIRDYK---GTLLVISH 512
Cdd:TIGR01842 493 LANAIKALKargITVVVITH 512
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
338-528 |
1.81e-13 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 69.47 E-value: 1.81e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKnIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI------------ERADFNSVYi 405
Cdd:cd03259 1 LELKGLSKTYGSV-RALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEIlidgrdvtgvppERRNIGMVF- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 406 dQDYSMINHsLSV---IQQAESFNWLPLPEHEVKTILSRFLFGKETW-DKSCSVLSGGERMRLLLA-CLSITgkaPDIII 480
Cdd:cd03259 79 -QDYALFPH-LTVaenIAFGLKLRGVPKAEIRARVRELLELVGLEGLlNRYPHELSGGQQQRVALArALARE---PSLLL 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 481 LDEPTNNLDlqniEILTNAIRDY--------KGTLLVISHDDvfSEEINIETRILL 528
Cdd:cd03259 154 LDEPLSALD----AKLREELREElkelqrelGITTIYVTHDQ--EEALALADRIAV 203
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
356-515 |
2.48e-13 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 68.92 E-value: 2.48e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 356 PLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQDYS----MINHS------LSViqqAESF 425
Cdd:TIGR01189 18 GLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEPHenilYLGHLpglkpeLSA---LENL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 426 NWL-PLPEHEVKTILSRF----LFGKEtwDKSCSVLSGGERMRLLLACLSITGkAPdIIILDEPTNNLDLQNIEILTNAI 500
Cdd:TIGR01189 95 HFWaAIHGGAQRTIEDALaavgLTGFE--DLPAAQLSAGQQRRLALARLWLSR-RP-LWILDEPTTALDKAGVALLAGLL 170
|
170
....*....|....*...
gi 639228517 501 RDY---KGTLLVISHDDV 515
Cdd:TIGR01189 171 RAHlarGGIVLLTTHQDL 188
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
357-513 |
2.71e-13 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 69.39 E-value: 2.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-------------ERADF--------NSVYidqdysminHS 415
Cdd:cd03219 19 VSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVlfdgeditglpphEIARLgigrtfqiPRLF---------PE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 416 LSVI---------QQAESFNWLPLPEHE------VKTILSRF-LFGKetWDKSCSVLSGGERMRLLLACLSITGkaPDII 479
Cdd:cd03219 90 LTVLenvmvaaqaRTGSGLLLARARREErearerAEELLERVgLADL--ADRPAGELSYGQQRRLEIARALATD--PKLL 165
|
170 180 190
....*....|....*....|....*....|....*..
gi 639228517 480 ILDEPTNNLDLQNIEILTNAIRDYKG---TLLVISHD 513
Cdd:cd03219 166 LLDEPAAGLNPEETEELAELIRELRErgiTVLLVEHD 202
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-171 |
2.73e-13 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 70.52 E-value: 2.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVY---------YLP-- 69
Cdd:COG4152 1 MLELKGLTKRFGDKTAV-DDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLdpedrrrigYLPee 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 70 -------QILEQ---FdtqsiARALGVQKKlSALREILEgivteenitvlddnW----DLEEKIKQALETwglldftade 135
Cdd:COG4152 80 rglypkmKVGEQlvyL-----ARLKGLSKA-EAKRRADE--------------WlerlGLGDRANKKVEE---------- 129
|
170 180 190
....*....|....*....|....*....|....*..
gi 639228517 136 smnrLSGGQKTKV-LIAGIeIHQPDIILMDEPTNHLD 171
Cdd:COG4152 130 ----LSKGNQQKVqLIAAL-LHDPELLILDEPFSGLD 161
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
4-195 |
3.62e-13 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 69.27 E-value: 3.62e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKEILFeNLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpqileQFDTQSIARA 83
Cdd:PRK11124 5 LNGINCFYGAHQALF-DITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGN---------HFDFSKTPSD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 84 lgvqKKLSALREILeGIVTEE-----NITVLDD---------NWDLEEKIKQA---LETWGLLDFtADESMNRLSGGQKT 146
Cdd:PRK11124 75 ----KAIRELRRNV-GMVFQQynlwpHLTVQQNlieapcrvlGLSKDQALARAeklLERLRLKPY-ADRFPLHLSGGQQQ 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 639228517 147 KVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHD 195
Cdd:PRK11124 149 RVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRelaETGITQVIVTHE 200
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1-196 |
4.26e-13 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 71.02 E-value: 4.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHpDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqfdtQSI 80
Cdd:PRK11607 19 LLEIRNLTKSF-DGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDG--------------VDL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKKLSALRE---ILEGIVTEENIT--VLDDNW---DLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAG 152
Cdd:PRK11607 84 SHVPPYQRPINMMFQsyaLFPHMTVEQNIAfgLKQDKLpkaEIASRVNEMLGLVHMQEF-AKRKPHQLSGGQRQRVALAR 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 153 IEIHQPDIILMDEPTNHLDRQSREQL----YEFIENTNKTLLVVSHDR 196
Cdd:PRK11607 163 SLAKRPKLLLLDEPMGALDKKLRDRMqlevVDILERVGVTCVMVTHDQ 210
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
2-203 |
4.56e-13 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 67.94 E-value: 4.56e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAgdirTEGSVYYLPQILEQFDTQSIA 81
Cdd:cd03217 1 LEIKDLHVSVGGKEIL-KGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKYEV----TEGEILFKGEDITDLPPEERA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RA---LGVQ--------KKLSALREILEGivteenitvlddnwdleekikqaletwglldftadesmnrLSGGQKTKVLI 150
Cdd:cd03217 76 RLgifLAFQyppeipgvKNADFLRYVNEG----------------------------------------FSGGEKKRNEI 115
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 151 AGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHDRTLLNLLP 203
Cdd:cd03217 116 LQLLLLEPDLAILDEPDSGLDIDALRLVAEVINklrEEGKSVLIITHYQRLLDYIK 171
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
17-180 |
4.82e-13 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 69.50 E-value: 4.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 17 LFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQ---ILEQFDTQSIarALGVQKKLSAL 93
Cdd:cd03291 52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGRISFSSQfswIMPGTIKENI--IFGVSYDEYRY 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 94 REILEGIVTEENITvlddnwDLEEKIKQALETWGLLdftadesmnrLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQ 173
Cdd:cd03291 130 KSVVKACQLEEDIT------KFPEKDNTVLGEGGIT----------LSGGQRARISLARAVYKDADLYLLDSPFGYLDVF 193
|
....*..
gi 639228517 174 SREQLYE 180
Cdd:cd03291 194 TEKEIFE 200
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
24-198 |
5.03e-13 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 68.65 E-value: 5.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 24 IVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVyyLPQILEQFDTQSIARALG-------VQKKLSALREI 96
Cdd:PRK10584 32 VVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQP--LHQMDEEARAKLRAKHVGfvfqsfmLIPTLNALENV 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 97 -LEGIVTEENitvldDNwDLEEKIKQALETWGLLDfTADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSR 175
Cdd:PRK10584 110 eLPALLRGES-----SR-QSRNGAKALLEQLGLGK-RLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTG 182
|
170 180
....*....|....*....|....*..
gi 639228517 176 EQLYEFIENTNK----TLLVVSHDRTL 198
Cdd:PRK10584 183 DKIADLLFSLNRehgtTLILVTHDLQL 209
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
2-194 |
5.81e-13 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 68.45 E-value: 5.81e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDK---EILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTpsaGDIRTEGSVYylpqileqFDTQ 78
Cdd:cd03234 4 LPWWDVGLKAKNWnkyARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVE---GGGTTSGQIL--------FNGQ 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 SIARALgVQKKLSALRE---ILEGIVTEENIT---VLDDNWDLEEKIKQALETWGLLDFTADES-----MNRLSGGQKTK 147
Cdd:cd03234 73 PRKPDQ-FQKCVAYVRQddiLLPGLTVRETLTytaILRLPRKSSDAIRKKRVEDVLLRDLALTRiggnlVKGISGGERRR 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 639228517 148 VLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENT---NKTLLVVSH 194
Cdd:cd03234 152 VSIAVQLLWDPKVLILDEPTSGLDSFTALNLVSTLSQLarrNRIVILTIH 201
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
19-178 |
5.81e-13 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 69.05 E-value: 5.81e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTE------GSVYYLPQILEQFdTQSIARALGVQKKLSA 92
Cdd:PRK15112 30 KPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDdhplhfGDYSYRSQRIRMI-FQDPSTSLNPRQRISQ 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 93 LREILEGIVTEENITvlddnwDLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDR 172
Cdd:PRK15112 109 ILDFPLRLNTDLEPE------QREKQIIETLRQVGLLPDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDM 182
|
....*.
gi 639228517 173 QSREQL 178
Cdd:PRK15112 183 SMRSQL 188
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
17-180 |
5.93e-13 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 71.87 E-value: 5.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 17 LFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQ---ILEQFDTQSIarALGVQKKLSAL 93
Cdd:TIGR01271 441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGRISFSPQtswIMPGTIKDNI--IFGLSYDEYRY 518
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 94 REILEGIVTEENITVlddnwdLEEKIKQALETWGLldftadesmnRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQ 173
Cdd:TIGR01271 519 TSVIKACQLEEDIAL------FPEKDKTVLGEGGI----------TLSGGQRARISLARAVYKDADLYLLDSPFTHLDVV 582
|
....*..
gi 639228517 174 SREQLYE 180
Cdd:TIGR01271 583 TEKEIFE 589
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
336-513 |
6.82e-13 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 68.64 E-value: 6.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 336 ILIKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradfnsvYIDQDYSminhS 415
Cdd:PRK13548 1 AMLEARNLSVRLGGRTLLDD-VSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVR-------LNGRPLA----D 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 416 LSVIQQAE-----------SFNW------------LPLPEHEVKTILSRFL-------FGketwDKSCSVLSGGERMRL- 464
Cdd:PRK13548 69 WSPAELARrravlpqhsslSFPFtveevvamgrapHGLSRAEDDALVAAALaqvdlahLA----GRDYPQLSGGEQQRVq 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 465 ---LLACLSITGKAPDIIILDEPTNNLDL---QNI-EILTNAIRDYKGTLLVISHD 513
Cdd:PRK13548 145 larVLAQLWEPDGPPRWLLLDEPTSALDLahqHHVlRLARQLAHERGLAVIVVLHD 200
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
20-198 |
7.45e-13 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 68.48 E-value: 7.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSIARaLGVQKKLSALReILEG 99
Cdd:PRK11300 23 NVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRG------QHIEGLPGHQIAR-MGVVRTFQHVR-LFRE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 100 IVTEENITV-----LDDNW------------DLEEKIKQA---LETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPD 159
Cdd:PRK11300 95 MTVIENLLVaqhqqLKTGLfsgllktpafrrAESEALDRAatwLERVGLLEH-ANRQAGNLAYGQQRRLEIARCMVTQPE 173
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 639228517 160 IILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHDRTL 198
Cdd:PRK11300 174 ILMLDEPAAGLNPKETKELDELIaelrNEHNVTVLLIEHDMKL 216
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
21-171 |
7.63e-13 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 68.33 E-value: 7.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 21 LNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPsagdirtEGSVYYLPQILEQFDTQSIA--RA-LGVQKKLSALREIL 97
Cdd:COG4138 15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGLLPG-------QGEILLNGRPLSDWSAAELArhRAyLSQQQSPPFAMPVF 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 98 E--------GIVTEENITVLDDnwdleekIKQALetwGLLDFTAdESMNRLSGGQKTKVLIAGI--EIHqPDI------I 161
Cdd:COG4138 88 QylalhqpaGASSEAVEQLLAQ-------LAEAL---GLEDKLS-RPLTQLSGGEWQRVRLAAVllQVW-PTInpegqlL 155
|
170
....*....|
gi 639228517 162 LMDEPTNHLD 171
Cdd:COG4138 156 LLDEPMNSLD 165
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
2-202 |
8.87e-13 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 68.17 E-value: 8.87e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGL--LTPSAGDIRTEGSvyylpQILEqFDTQS 79
Cdd:COG0396 1 LEIKNLHVSVEGKEIL-KGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHpkYEVTSGSILLDGE-----DILE-LSPDE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 80 IARA---LGVQ--------KKLSALREILeGIVTEENITVLDdnwdLEEKIKQALETWGLldftaDESM-NR-----LSG 142
Cdd:COG0396 74 RARAgifLAFQypveipgvSVSNFLRTAL-NARRGEELSARE----FLKLLKEKMKELGL-----DEDFlDRyvnegFSG 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639228517 143 GQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHDRTLLNLL 202
Cdd:COG0396 144 GEKKRNEILQMLLLEPKLAILDETDSGLDIDALRIVAEGVNklrSPDRGILIITHYQRILDYI 206
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
338-515 |
9.89e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 68.54 E-value: 9.89e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIW-KKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQDYSMIN 413
Cdd:PRK13637 3 IKIENLTHIYMEGTPFeKKALDNVnieIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVKLSDIR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 414 HSLSVIQQaesfnwlpLPEHEV--KTILSRFLFG---------------KETW-----------DKSCSVLSGGERMRLL 465
Cdd:PRK13637 83 KKVGLVFQ--------YPEYQLfeETIEKDIAFGpinlglseeeienrvKRAMnivgldyedykDKSPFELSGGQKRRVA 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 466 LAclSITGKAPDIIILDEPTNNLDLQNIEILTNAIRD----YKGTLLVISH--DDV 515
Cdd:PRK13637 155 IA--GVVAMEPKILILDEPTAGLDPKGRDEILNKIKElhkeYNMTIILVSHsmEDV 208
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
17-202 |
9.99e-13 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 67.68 E-value: 9.99e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 17 LFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLL--TPSAGDIRtegsvyyLPQIleQFDTQ-SIARALGVQKKLSAL 93
Cdd:COG2401 45 VLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVD-------VPDN--QFGREaSLIDAIGRKGDFKDA 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 94 REILegivteeNITVLDDNWDLEEKIKQaletwglldftadesmnrLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQ 173
Cdd:COG2401 116 VELL-------NAVGLSDAVLWLRRFKE------------------LSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQ 170
|
170 180 190
....*....|....*....|....*....|...
gi 639228517 174 -SRE---QLYEFIENTNKTLLVVSHDRTLLNLL 202
Cdd:COG2401 171 tAKRvarNLQKLARRAGITLVVATHHYDVIDDL 203
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
12-194 |
1.01e-12 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 67.05 E-value: 1.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 12 PDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpqileqfDTQSIaralgvqkKLS 91
Cdd:cd03369 18 PDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGI-----------DISTI--------PLE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 92 ALREILeGIVTEENI-------TVLD--DNWDlEEKIKQALETwglldftaDESMNRLSGGQKTKVLIAGIEIHQPDIIL 162
Cdd:cd03369 79 DLRSSL-TIIPQDPTlfsgtirSNLDpfDEYS-DEEIYGALRV--------SEGGLNLSQGQRQLLCLARALLKRPRVLV 148
|
170 180 190
....*....|....*....|....*....|....
gi 639228517 163 MDEPTNHLDRQSREQLYEFI--ENTNKTLLVVSH 194
Cdd:cd03369 149 LDEATASIDYATDALIQKTIreEFTNSTILTIAH 182
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
19-210 |
1.05e-12 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 70.22 E-value: 1.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQILEQFDTQSIA-RALGV---QKKLSALR 94
Cdd:TIGR03269 301 DNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRVGDEWVDMTKPGPDGRGRAkRYIGIlhqEYDLYPHR 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 95 EILEGIVTEENITVLDdnwdlEEKIKQALETWGLLDFTADESMN-------RLSGGQKTKVLIAGIEIHQPDIILMDEPT 167
Cdd:TIGR03269 381 TVLDNLTEAIGLELPD-----ELARMKAVITLKMVGFDEEKAEEildkypdELSEGERHRVALAQVLIKEPRIVILDEPT 455
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 639228517 168 NHLDRQSREQLYEFI----ENTNKTLLVVSHDRTLLNLLPKTAELSR 210
Cdd:TIGR03269 456 GTMDPITKVDVTHSIlkarEEMEQTFIIVSHDMDFVLDVCDRAALMR 502
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
26-171 |
1.07e-12 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 68.29 E-value: 1.07e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 26 NKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQ----ILEQFDTQSIARalgVQKKLS---------A 92
Cdd:COG4598 32 RKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRLKPdrdgELVPADRRQLQR---IRTRLGmvfqsfnlwS 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 93 LREILEGiVTEENITVLD-DNWDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLD 171
Cdd:COG4598 109 HMTVLEN-VIEAPVHVLGrPKAEAIERAEALLAKVGLADK-RDAYPAHLSGGQQQRAAIARALAMEPEVMLFDEPTSALD 186
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
25-188 |
1.09e-12 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 68.12 E-value: 1.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 25 VNKGDKIAIVGNNGSGKSTLLKLISGLLTpsaGDIRTEGSVYYLPQILE------------QFDTQSIARALGVQKKLSA 92
Cdd:PRK09984 27 IHHGEMVALLGPSGSGKSTLLRHLSGLIT---GDKSAGSHIELLGRTVQregrlardirksRANTGYIFQQFNLVNRLSV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 93 LREILEGIVTEENITVLDDNW---DLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNH 169
Cdd:PRK09984 104 LENVLIGALGSTPFWRTCFSWftrEQKQRALQALTRVGMVHF-AHQRVSTLSGGQQQRVAIARALMQQAKVILADEPIAS 182
|
170
....*....|....*....
gi 639228517 170 LDRQSREQLYEFIENTNKT 188
Cdd:PRK09984 183 LDPESARIVMDTLRDINQN 201
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
2-166 |
1.15e-12 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 67.57 E-value: 1.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG--------------SVYY 67
Cdd:cd03218 1 LRAENLSKRYGKRKVV-NGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGqditklpmhkrarlGIGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 68 LPQileqfdTQSIARALGVQKKLSALREILEgivteenitvlDDNWDLEEKIKQALETWGlLDFTADESMNRLSGGQKTK 147
Cdd:cd03218 80 LPQ------EASIFRKLTVEENILAVLEIRG-----------LSKKEREEKLEELLEEFH-ITHLRKSKASSLSGGERRR 141
|
170
....*....|....*....
gi 639228517 148 VLIAGIEIHQPDIILMDEP 166
Cdd:cd03218 142 VEIARALATNPKFLLLDEP 160
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-218 |
1.19e-12 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 68.02 E-value: 1.19e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGL--LTPSAgdiRTEGSVYylpqileqFDTQS 79
Cdd:PRK14247 4 IEIRDLKVSFGQVEVL-DGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLieLYPEA---RVSGEVY--------LDGQD 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 80 IAR--ALGVQKKLSALREILEGIVTE---ENIT-------VLDDNWDLEEKIKQALET---WGLLDFTADESMNRLSGGQ 144
Cdd:PRK14247 72 IFKmdVIELRRRVQMVFQIPNPIPNLsifENVAlglklnrLVKSKKELQERVRWALEKaqlWDEVKDRLDAPAGKLSGGQ 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK--TLLVVSHdrtllnLLPKTAELSRKEMMLYGG 218
Cdd:PRK14247 152 QQRLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKdmTIVLVTH------FPQQAARISDYVAFLYKG 221
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
19-513 |
1.29e-12 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 70.12 E-value: 1.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKS-TLLKLISGLLTPSA----GDIRTEG-SVYYLP-QILEQFDTQSIARAL------- 84
Cdd:PRK15134 26 NDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPPVvypsGDIRFHGeSLLHASeQTLRGVRGNKIAMIFqepmvsl 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 85 ----GVQKKLSALREILEGIVTE----ENITVLDdnwdlEEKIKQALETwgLLDFTadesmNRLSGGQKTKVLIAGIEIH 156
Cdd:PRK15134 106 nplhTLEKQLYEVLSLHRGMRREaargEILNCLD-----RVGIRQAAKR--LTDYP-----HQLSGGERQRVMIAMALLT 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 157 QPDIILMDEPTNHLDRQSREQ----LYEFIENTNKTLLVVSHDrtlLNLLPKTAElsRKEMMLYGgnydsykeqKQIQQN 232
Cdd:PRK15134 174 RPELLIADEPTTALDVSVQAQilqlLRELQQELNMGLLFITHN---LSIVRKLAD--RVAVMQNG---------RCVEQN 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 233 ALQNSIKNTENALKkakateretlerQQKLDAkgkkkqEKAGVAKIMmntlrnnAENSTAKIRdthsdkieglsqeLQQL 312
Cdd:PRK15134 240 RAATLFSAPTHPYT------------QKLLNS------EPSGDPVPL-------PEPASPLLD-------------VEQL 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 313 RRGVPLtdqmklgfdqanlhRGKILIKAEHINHAYQDkniwkkpLDVVVSSGERILIIGENGSGKTTlIKLLLGQMKPSE 392
Cdd:PRK15134 282 QVAFPI--------------RKGILKRTVDHNVVVKN-------ISFTLRPGETLGLVGESGSGKST-TGLALLRLINSQ 339
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 393 GTIE-----------------RADFNSVYidQD-YSMINHSLSVIQQAESFNWLPLP-------EHEVKTILSRFLFGKE 447
Cdd:PRK15134 340 GEIWfdgqplhnlnrrqllpvRHRIQVVF--QDpNSSLNPRLNVLQIIEEGLRVHQPtlsaaqrEQQVIAVMEEVGLDPE 417
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 448 TWDKSCSVLSGGERMRLLLACLSITgkAPDIIILDEPTNNLD----LQNIEILTNAIRDYKGTLLVISHD 513
Cdd:PRK15134 418 TRHRYPAEFSGGQRQRIAIARALIL--KPSLIILDEPTSSLDktvqAQILALLKSLQQKHQLAYLFISHD 485
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
1-261 |
1.32e-12 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 68.11 E-value: 1.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqfdtqsi 80
Cdd:PRK13638 1 MLATSDLWFRYQDEPVL-KGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQG----------------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 aRALGVQKK-LSALREILEGIVT--EENITVLDDNWDL-----------EEKIKQALETWGLLDFTA--DESMNRLSGGQ 144
Cdd:PRK13638 63 -KPLDYSKRgLLALRQQVATVFQdpEQQIFYTDIDSDIafslrnlgvpeAEITRRVDEALTLVDAQHfrHQPIQCLSHGQ 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN---TNKTLLVVSHDrtlLNLLPKTAE----LSRKEMMLYG 217
Cdd:PRK13638 142 KKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAIIRRivaQGNHVIISSHD---IDLIYEISDavyvLRQGQILTHG 218
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 639228517 218 GNYDSYKEQKQIQQNALQNS--IK-NTENALKKAKaTERETLERQQK 261
Cdd:PRK13638 219 APGEVFACTEAMEQAGLTQPwlVKlHTQLGLPLCK-TETEFFHRMQK 264
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
338-512 |
1.42e-12 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 66.92 E-value: 1.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERadFNSVYIDQDYSMINH--- 414
Cdd:cd03269 1 LEVENVTKRFGRVTALDD-ISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLF--DGKPLDIAARNRIGYlpe 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 415 ------SLSVIQQAESFNWLP-LPEHEVKTILSRFL--FG-KETWDKSCSVLSGGERMRLLLACLSItgKAPDIIILDEP 484
Cdd:cd03269 78 erglypKMKVIDQLVYLAQLKgLKKEEARRRIDEWLerLElSEYANKRVEELSKGNQQKVQFIAAVI--HDPELLILDEP 155
|
170 180 190
....*....|....*....|....*....|.
gi 639228517 485 TNNLDLQNIEILTNAIRDYKG---TLLVISH 512
Cdd:cd03269 156 FSGLDPVNVELLKDVIRELARagkTVILSTH 186
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
1-195 |
1.73e-12 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 67.87 E-value: 1.73e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEIlFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqilEQFDTQSI 80
Cdd:PRK11831 7 LVDMRGVSFTRGNRCI-FDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDG---------ENIPAMSR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKKLSALreiLEGIVTEENITVLDD-NWDLEEK-----------IKQALETWGLLDfTADESMNRLSGGQKTKV 148
Cdd:PRK11831 77 SRLYTVRKRMSML---FQSGALFTDMNVFDNvAYPLREHtqlpapllhstVMMKLEAVGLRG-AAKLMPSELSGGMARRA 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 149 LIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTL----LVVSHD 195
Cdd:PRK11831 153 ALARAIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSALgvtcVVVSHD 203
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
24-202 |
1.79e-12 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 67.39 E-value: 1.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 24 IVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS-----VYYLPQILEQFDTQSIARALGVQKKLSALREI-- 96
Cdd:cd03236 22 VPREGQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDDPPDwdeilDEFRGSELQNYFTKLLEGDVKVIVKPQYVDLIpk 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 97 -LEGIVtEENITVLDDNWDLEEKIKQaLETWGLLDFTADEsmnrLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLD---R 172
Cdd:cd03236 102 aVKGKV-GELLKKKDERGKLDELVDQ-LELRHVLDRNIDQ----LSGGELQRVAIAAALARDADFYFFDEPSSYLDikqR 175
|
170 180 190
....*....|....*....|....*....|
gi 639228517 173 QSREQLYEFIENTNKTLLVVSHDRTLLNLL 202
Cdd:cd03236 176 LNAARLIRELAEDDNYVLVVEHDLAVLDYL 205
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
18-196 |
1.84e-12 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 66.69 E-value: 1.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 18 FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDI--RTEGSVYYL----P-QILE----------QFdtqsi 80
Cdd:COG4778 27 LDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSIlvRHDGGWVDLaqasPrEILAlrrrtigyvsQF----- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 araLGVQKKLSALReilegIVTEeniTVLDDNWDLEEKIKQALEtwgLLD-FTADESMNRL-----SGGQKTKVLIA-GI 153
Cdd:COG4778 102 ---LRVIPRVSALD-----VVAE---PLLERGVDREEARARARE---LLArLNLPERLWDLppatfSGGEQQRVNIArGF 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 639228517 154 eIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK---TLLVVSHDR 196
Cdd:COG4778 168 -IADPPLLLLDEPTASLDAANRAVVVELIEEAKArgtAIIGIFHDE 212
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
1-198 |
2.04e-12 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 69.78 E-value: 2.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLtPSAGDIRT---EGSVYYLPQ----ILE 73
Cdd:TIGR00954 451 GIKFENIPLVTPNGDVLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELW-PVYGGRLTkpaKGKLFYVPQrpymTLG 529
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 74 QFDTQSI--ARALGVQKK---LSALREILEgIVTEENITVLDDNWDleekikqALETWglldftadesMNRLSGGQKTKV 148
Cdd:TIGR00954 530 TLRDQIIypDSSEDMKRRglsDKDLEQILD-NVQLTHILEREGGWS-------AVQDW----------MDVLSGGEKQRI 591
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 639228517 149 LIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDRTL 198
Cdd:TIGR00954 592 AMARLFYHKPQFAILDECTSAVSVDVEGYMYRLCREFGITLFSVSHRKSL 641
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1-195 |
2.05e-12 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 68.18 E-value: 2.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNI--TYQHPDKEIL-FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqfdt 77
Cdd:COG1135 1 MIELENLskTFPTKGGPVTaLDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDG-------------- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 QSIArALGvQKKLSALR-EIleGIVTE-----ENITVLD--------DNWDLEEKIKQALEtwgLLDFT-----ADESMN 138
Cdd:COG1135 67 VDLT-ALS-ERELRAARrKI--GMIFQhfnllSSRTVAEnvalpleiAGVPKAEIRKRVAE---LLELVglsdkADAYPS 139
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 639228517 139 RLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHD 195
Cdd:COG1135 140 QLSGGQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRelglTIVLITHE 200
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
2-195 |
2.11e-12 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 69.23 E-value: 2.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqilEQFDTQSIA 81
Cdd:PRK10522 323 LELRNVTFAYQDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDG---------KPVTAEQPE 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RalgVQKKLSA------LREILEGIVTEENITVLDDNW----DLEEKIKqaLETWGLLDFtadesmnRLSGGQKTKV--L 149
Cdd:PRK10522 394 D---YRKLFSAvftdfhLFDQLLGPEGKPANPALVEKWlerlKMAHKLE--LEDGRISNL-------KLSKGQKKRLalL 461
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 639228517 150 IAGIEihQPDIILMDEPTNHLDRQSREQLYE----FIENTNKTLLVVSHD 195
Cdd:PRK10522 462 LALAE--ERDILLLDEWAADQDPHFRREFYQvllpLLQEMGKTIFAISHD 509
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
3-195 |
2.29e-12 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 67.12 E-value: 2.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 3 TLQNITYQHPDKeILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTQSIAR 82
Cdd:PRK10575 13 ALRNVSFRVPGR-TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDA------QPLESWSSKAFAR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 83 ALG-VQKKLSAlreiLEGIVTEENITVLDDNW---------DLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAG 152
Cdd:PRK10575 86 KVAyLPQQLPA----AEGMTVRELVAIGRYPWhgalgrfgaADREKVEEAISLVGLKPL-AHRLVDSLSGGERQRAWIAM 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 639228517 153 IEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHD 195
Cdd:PRK10575 161 LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQerglTVIAVLHD 207
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
338-512 |
2.43e-12 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 69.42 E-value: 2.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQD-----KNIwkkplDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeradfnsvYID-QDYSM 411
Cdd:COG1132 340 IEFENVSFSYPGdrpvlKDI-----SLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRI--------LIDgVDIRD 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 412 IN-----HSLSVIQQaES--FNwlplpehevKTILSRFLFGKET------WD--KSCSV--------------------- 455
Cdd:COG1132 407 LTleslrRQIGVVPQ-DTflFS---------GTIRENIRYGRPDatdeevEEaaKAAQAhefiealpdgydtvvgergvn 476
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639228517 456 LSGGERMRL-----LLaclsitgKAPDIIILDEPTNNLDLQNIEILTNAIRDY-KG-TLLVISH 512
Cdd:COG1132 477 LSGGQRQRIaiaraLL-------KDPPILILDEATSALDTETEALIQEALERLmKGrTTIVIAH 533
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
2-167 |
2.44e-12 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 66.39 E-value: 2.44e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFeNLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpQILEQFDTQSIA 81
Cdd:TIGR03410 1 LEVSNLNVYYGQSHILR-GVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGE-----DITKLPPHERAR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGV--QKklsalREILEGIVTEENI-TVLDDNWDLEEKIKQalETWGLldFTADESM-NR----LSGGQKTKVLIAGI 153
Cdd:TIGR03410 75 AGIAYvpQG-----REIFPRLTVEENLlTGLAALPRRSRKIPD--EIYEL--FPVLKEMlGRrggdLSGGQQQQLAIARA 145
|
170
....*....|....
gi 639228517 154 EIHQPDIILMDEPT 167
Cdd:TIGR03410 146 LVTRPKLLLLDEPT 159
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1-214 |
2.79e-12 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 69.37 E-value: 2.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKE---ILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDT 77
Cdd:PRK10535 4 LLELKDIRRSYPSGEeqvEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAG------QDVATLDA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 QSIARalgvqkklsaLR-----------EILEGIVTEENITVLDDNWDLEEKIKQA-----LETWGLLDfTADESMNRLS 141
Cdd:PRK10535 78 DALAQ----------LRrehfgfifqryHLLSHLTAAQNVEVPAVYAGLERKQRLLraqelLQRLGLED-RVEYQPSQLS 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 142 GGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK---TLLVVSHDRTLLNLLPKTAELSRKEMM 214
Cdd:PRK10535 147 GGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDrghTVIIVTHDPQVAAQAERVIEIRDGEIV 222
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
369-513 |
2.86e-12 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 65.99 E-value: 2.86e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 369 IIGENGSGKTTLIKLLLGQMKPSEGTIEradFNSVYIDQDYSMINHSLSVIQQaesFNWLP-----------------LP 431
Cdd:cd03263 33 LLGHNGAGKTTTLKMLTGELRPTSGTAY---INGYSIRTDRKAARQSLGYCPQ---FDALFdeltvrehlrfyarlkgLP 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 432 EHEVKTILSRFLFG---KETWDKSCSVLSGGERMRLLLAClSITGkAPDIIILDEPTNNLDLQNIEILTNAIRDYKG--T 506
Cdd:cd03263 107 KSEIKEEVELLLRVlglTDKANKRARTLSGGMKRKLSLAI-ALIG-GPSVLLLDEPTSGLDPASRRAIWDLILEVRKgrS 184
|
....*..
gi 639228517 507 LLVISHD 513
Cdd:cd03263 185 IILTTHS 191
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
2-195 |
2.95e-12 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 67.34 E-value: 2.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEIL----FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGdiRTEGSVYYLPQILEQF-D 76
Cdd:PRK13645 7 IILDNVSYTYAKKTPFefkaLNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETG--QTIVGDYAIPANLKKIkE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 77 TQSIARALGVQ---KKLSALREILEGIVTEENITVLDDNWDLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGI 153
Cdd:PRK13645 85 VKRLRKEIGLVfqfPEYQLFQETIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGI 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 639228517 154 EIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKT----LLVVSHD 195
Cdd:PRK13645 165 IAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEykkrIIMVTHN 210
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
2-194 |
3.34e-12 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 68.98 E-value: 3.34e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVyyLPQILEQFDTQSIA 81
Cdd:PRK10790 341 IDIDNVSFAYRDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRP--LSSLSHSVLRQGVA 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RalgVQKKLSALREILEGIVT-EENITvlddnwdlEEKIKQALETWGLLDFTAD----------ESMNRLSGGQKTKVLI 150
Cdd:PRK10790 419 M---VQQDPVVLADTFLANVTlGRDIS--------EEQVWQALETVQLAELARSlpdglytplgEQGNNLSVGQKQLLAL 487
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 151 AGIEIHQPDIILMDEPTNHLD---RQSREQLYEFI-ENTnkTLLVVSH 194
Cdd:PRK10790 488 ARVLVQTPQILILDEATANIDsgtEQAIQQALAAVrEHT--TLVVIAH 533
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
357-511 |
3.56e-12 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 65.67 E-value: 3.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQDYSM--INH------SLSVIQQAEsFnWl 428
Cdd:PRK13539 21 LSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEAChyLGHrnamkpALTVAENLE-F-W- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 429 plpehevktilSRFLFGKETW--DKSCSV------------LSGGERMRLLLACLSITGkAPdIIILDEPTNNLDLQNIE 494
Cdd:PRK13539 98 -----------AAFLGGEELDiaAALEAVglaplahlpfgyLSAGQKRRVALARLLVSN-RP-IWILDEPTAALDAAAVA 164
|
170
....*....|....*....
gi 639228517 495 ILTNAIRDY--KGTLLVIS 511
Cdd:PRK13539 165 LFAELIRAHlaQGGIVIAA 183
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
11-198 |
3.63e-12 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 66.63 E-value: 3.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 11 HPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDTqSIARA------L 84
Cdd:PRK10419 22 HQHQTVL-NNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRG------EPLAKLNR-AQRKAfrrdiqM 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 85 GVQKKLSAL--REILEGIVTE--ENITVLDDNwDLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIHQPDI 160
Cdd:PRK10419 94 VFQDSISAVnpRKTVREIIREplRHLLSLDKA-ERLARASEMLRAVDLDDSVLDKRPPQLSGGQLQRVCLARALAVEPKL 172
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 639228517 161 ILMDEPTNHLDR----QSREQLYEFIENTNKTLLVVSHDRTL 198
Cdd:PRK10419 173 LILDEAVSNLDLvlqaGVIRLLKKLQQQFGTACLFITHDLRL 214
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
26-195 |
3.67e-12 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 66.53 E-value: 3.67e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 26 NKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQ----ILEQFDtqsiaralgvQKKLSALREILEGIV 101
Cdd:PRK10619 29 NAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRdkdgQLKVAD----------KNQLRLLRTRLTMVF 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 102 TEENI----TVLDD------------NWDLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIHQPDIILMDE 165
Cdd:PRK10619 99 QHFNLwshmTVLENvmeapiqvlglsKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQRVSIARALAMEPEVLLFDE 178
|
170 180 190
....*....|....*....|....*....|...
gi 639228517 166 PTNHLDRQSREQLYEFIEN---TNKTLLVVSHD 195
Cdd:PRK10619 179 PTSALDPELVGEVLRIMQQlaeEGKTMVVVTHE 211
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
358-527 |
4.20e-12 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 68.82 E-value: 4.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 358 DVVVSSGERILIIGENGSGKTTLIKLLLG--------------------QMKP------------SEGTIERADFNSVY- 404
Cdd:PRK11147 23 ELHIEDNERVCLVGRNGAGKSTLMKILNGevllddgriiyeqdlivarlQQDPprnvegtvydfvAEGIEEQAEYLKRYh 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 405 -----IDQDYS--MINHSLSVIQQAESFNWLPLpEHEVKTILSRFlfgKETWDKSCSVLSGGERMRLLLACLSITgkAPD 477
Cdd:PRK11147 103 dishlVETDPSekNLNELAKLQEQLDHHNLWQL-ENRINEVLAQL---GLDPDAALSSLSGGWLRKAALGRALVS--NPD 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 639228517 478 IIILDEPTNNLDLQNIEILTNAIRDYKGTLLVISHDDVFSEeiNIETRIL 527
Cdd:PRK11147 177 VLLLDEPTNHLDIETIEWLEGFLKTFQGSIIFISHDRSFIR--NMATRIV 224
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
13-195 |
5.42e-12 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 68.19 E-value: 5.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 13 DKEILFENLNFIVNKGDKIAIVGNNGSGKST----LLKLIsglltpsagdiRTEGSVYYLPQILEQFDTQS---IARALG 85
Cdd:PRK15134 297 DHNVVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLI-----------NSQGEIWFDGQPLHNLNRRQllpVRHRIQ 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 86 V---------QKKLSALREILEGI-VTEENITVLDDnwdlEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEI 155
Cdd:PRK15134 366 VvfqdpnsslNPRLNVLQIIEEGLrVHQPTLSAAQR----EQQVIAVMEEVGLDPETRHRYPAEFSGGQRQRIAIARALI 441
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 639228517 156 HQPDIILMDEPTNHLDRQSREQLYEFIENTNKT----LLVVSHD 195
Cdd:PRK15134 442 LKPSLIILDEPTSSLDKTVQAQILALLKSLQQKhqlaYLFISHD 485
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
2-195 |
5.91e-12 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 65.96 E-value: 5.91e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEIlfenlnfivnkgdkIAIVGNNGSGKSTLLKLISGL--LTPSAgdiRTEGSVYYLPQIL--EQFDT 77
Cdd:PRK14243 24 LAVKNVWLDIPKNQI--------------TAFIGPSGCGKSTILRCFNRLndLIPGF---RVEGKVTFHGKNLyaPDVDP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 QSIARALGV--QKKLSALREILEGIVTEENITVLDDnwDLEEKIKQALETWGLLDFTAD---ESMNRLSGGQKTKVLIAG 152
Cdd:PRK14243 87 VEVRRRIGMvfQKPNPFPKSIYDNIAYGARINGYKG--DMDELVERSLRQAALWDEVKDklkQSGLSLSGGQQQRLCIAR 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 639228517 153 IEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK--TLLVVSHD 195
Cdd:PRK14243 165 AIAVQPEVILMDEPCSALDPISTLRIEELMHELKEqyTIIIVTHN 209
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
337-513 |
6.04e-12 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 66.19 E-value: 6.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNiwKKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE--------------RAD 399
Cdd:PRK13635 5 IIRVEHISFRYPDAA--TYALKDVsfsVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITvggmvlseetvwdvRRQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 400 FNSVYIDQD-------------YSMINHSLSVIQQAESFNWlplPEHEVKtiLSRFLfgketwDKSCSVLSGGERMRLLL 466
Cdd:PRK13635 83 VGMVFQNPDnqfvgatvqddvaFGLENIGVPREEMVERVDQ---ALRQVG--MEDFL------NREPHRLSGGQKQRVAI 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 467 AclSITGKAPDIIILDEPTNNLDLQNIEILTNAIRDYKG----TLLVISHD 513
Cdd:PRK13635 152 A--GVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEqkgiTVLSITHD 200
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
357-519 |
8.96e-12 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 64.44 E-value: 8.96e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI----ERADFNSVYIDQDYSMINHS------LSVIqqaESFN 426
Cdd:cd03231 19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVllngGPLDFQRDSIARGLLYLGHApgikttLSVL---ENLR 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 427 WLPlPEHEVKTILSRF----LFGKEtwDKSCSVLSGGERMRLLLACLSITGkaPDIIILDEPTNNLDLQNIEILTNAIRD 502
Cdd:cd03231 96 FWH-ADHSDEQVEEALarvgLNGFE--DRPVAQLSAGQQRRVALARLLLSG--RPLWILDEPTTALDKAGVARFAEAMAG 170
|
170 180
....*....|....*....|
gi 639228517 503 Y---KGTLLVISHDDVFSEE 519
Cdd:cd03231 171 HcarGGMVVLTTHQDLGLSE 190
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
338-512 |
9.18e-12 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 64.94 E-value: 9.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGtieradfnSVYID-QDYSMIN-HS 415
Cdd:cd03253 1 IEFENVTFAYDPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSG--------SILIDgQDIREVTlDS 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 416 LS-----VIQQAESFNwlplpehevKTILSRFLFGK-----ETWDKSCSV------------------------LSGGER 461
Cdd:cd03253 73 LRraigvVPQDTVLFN---------DTIGYNIRYGRpdatdEEVIEAAKAaqihdkimrfpdgydtivgerglkLSGGEK 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 639228517 462 MRLLLACLSItgKAPDIIILDEPTNNLDLQNIEILTNAIRD-YKG-TLLVISH 512
Cdd:cd03253 144 QRVAIARAIL--KNPPILLLDEATSALDTHTEREIQAALRDvSKGrTTIVIAH 194
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
20-195 |
1.17e-11 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 67.02 E-value: 1.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLtPSAGDIRtegsvyylpqileqFDTQSIARALGvqKKLSALR----- 94
Cdd:COG4172 304 GVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIR--------------FDGQDLDGLSR--RALRPLRrrmqv 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 95 ----------------EILEgivteENITVLDDNWDLEE---KIKQALETWGLldftADESMNR----LSGGQKTKVLIA 151
Cdd:COG4172 367 vfqdpfgslsprmtvgQIIA-----EGLRVHGPGLSAAErraRVAEALEEVGL----DPAARHRypheFSGGQRQRIAIA 437
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 152 GIEIHQPDIILMDEPTNHLDR-------------QSREQL-YEFIentnktllvvSHD 195
Cdd:COG4172 438 RALILEPKLLVLDEPTSALDVsvqaqildllrdlQREHGLaYLFI----------SHD 485
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
360-522 |
1.18e-11 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 67.12 E-value: 1.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 360 VVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIER-ADFNSVyID-------QDY--SMINHSLSV---IQQAESfn 426
Cdd:COG1245 95 VPKKGKVTGILGPNGIGKSTALKILSGELKPNLGDYDEePSWDEV-LKrfrgtelQDYfkKLANGEIKVahkPQYVDL-- 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 427 wlpLPEH---EVKTILSR------------FLFGKETWDKSCSVLSGGERMRLLLA-CLSitgKAPDIIILDEPTNNLDL 490
Cdd:COG1245 172 ---IPKVfkgTVRELLEKvdergkldelaeKLGLENILDRDISELSGGELQRVAIAaALL---RDADFYFFDEPSSYLDI 245
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 639228517 491 -QNIEIlTNAIRDY---KGTLLVISHD----DVFSEEINI 522
Cdd:COG1245 246 yQRLNV-ARLIRELaeeGKYVLVVEHDlailDYLADYVHI 284
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
11-199 |
1.18e-11 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 67.15 E-value: 1.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 11 HPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqfdtQSIaRALgvqkKL 90
Cdd:COG5265 368 DPERPIL-KGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDG--------------QDI-RDV----TQ 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 91 SALREILeGIVTEEniTVL-DD---------NWDL-EEKIKQALETWGLLDFTAD-----ESMN-----RLSGGQKTKVL 149
Cdd:COG5265 428 ASLRAAI-GIVPQD--TVLfNDtiayniaygRPDAsEEEVEAAARAAQIHDFIESlpdgyDTRVgerglKLSGGEKQRVA 504
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 639228517 150 IAGIEIHQPDIILMDEPTNHLDRQSrEQlyefieNTNKTLLVVSHDRTLL 199
Cdd:COG5265 505 IARTLLKNPPILIFDEATSALDSRT-ER------AIQAALREVARGRTTL 547
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
1-194 |
1.24e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 63.74 E-value: 1.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFENLNFIVNKgdkIAIV-GNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyYLPQILEQFDTQs 79
Cdd:PRK13541 1 MLSLHQLQFNIEQKNLFDLSITFLPSA---ITYIkGANGCGKSSLLRMIAGIMQPSSGNIYYKNC--NINNIAKPYCTY- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 80 IARALGVQKKLSalreilegivTEENITVLDDNWDLEEKIKQALETWGLLDFTaDESMNRLSGGQKTKVLIAGIEIHQPD 159
Cdd:PRK13541 75 IGHNLGLKLEMT----------VFENLKFWSEIYNSAETLYAAIHYFKLHDLL-DEKCYSLSSGMQKIVAIARLIACQSD 143
|
170 180 190
....*....|....*....|....*....|....*...
gi 639228517 160 IILMDEPTNHLDRQSREQLYEFI---ENTNKTLLVVSH 194
Cdd:PRK13541 144 LWLLDEVETNLSKENRDLLNNLIvmkANSGGIVLLSSH 181
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
357-514 |
1.51e-11 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 63.97 E-value: 1.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFN-SVYIDQDYSMINHSLSVIQQaeSFNWLP------ 429
Cdd:cd03292 20 INISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDvSDLRGRAIPYLRRKIGVVFQ--DFRLLPdrnvye 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 430 ----------LPEHE----VKTILSRF-LFGKEtwDKSCSVLSGGERMRLLLAcLSITgKAPDIIILDEPTNNLDLQN-- 492
Cdd:cd03292 98 nvafalevtgVPPREirkrVPAALELVgLSHKH--RALPAELSGGEQQRVAIA-RAIV-NSPTILIADEPTGNLDPDTtw 173
|
170 180
....*....|....*....|...
gi 639228517 493 -IEILTNAIRDYKGTLLVISHDD 514
Cdd:cd03292 174 eIMNLLKKINKAGTTVVVATHAK 196
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
1-200 |
1.78e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 63.43 E-value: 1.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDkEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIrtegsvyylpqileQFDTQSI 80
Cdd:PRK13540 1 MLDVIELDFDYHD-QPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEI--------------LFERQSI 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGV-QKKLSALRE---ILEGIVTEEN----ITVLDDNWDLEEkikqaLETWGLLDFTADESMNRLSGGQKTKVLIAG 152
Cdd:PRK13540 66 KKDLCTyQKQLCFVGHrsgINPYLTLRENclydIHFSPGAVGITE-----LCRLFSLEHLIDYPCGLLSSGQKRQVALLR 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 153 IEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK---TLLVVSHDRTLLN 200
Cdd:PRK13540 141 LWMSKAKLWLLDEPLVALDELSLLTIITKIQEHRAkggAVLLTSHQDLPLN 191
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
13-300 |
1.86e-11 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 66.98 E-value: 1.86e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 13 DKEIlFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDI----------------RTE-GSVYYLPQILEQF 75
Cdd:PTZ00265 397 DVEI-YKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIiindshnlkdinlkwwRSKiGVVSQDPLLFSNS 475
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 76 DTQSIARALGVQKKLSALREILE--GIVTEENITVLDD-----NWDLEEkIKQALETWGLL------------------- 129
Cdd:PTZ00265 476 IKNNIKYSLYSLKDLEALSNYYNedGNDSQENKNKRNScrakcAGDLND-MSNTTDSNELIemrknyqtikdsevvdvsk 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 130 -----DFTAD----------ESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE----NTNKTLL 190
Cdd:PTZ00265 555 kvlihDFVSAlpdkyetlvgSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINnlkgNENRITI 634
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 191 VVSHDRTLLNLLPKTAELSRKE----MMLYGGNYDSYKEQKQIQQNALQNSIKNTENALKKAKATERETLERQQKLDAKG 266
Cdd:PTZ00265 635 IIAHRLSTIRYANTIFVLSNRErgstVDVDIIGEDPTKDNKENNNKNNKDDNNNNNNNNNNKINNAGSYIIEQGTHDALM 714
|
330 340 350
....*....|....*....|....*....|....
gi 639228517 267 KKKQekaGVAKIMMNTLRNNAENSTAKIRDTHSD 300
Cdd:PTZ00265 715 KNKN---GIYYTMINNQKVSSKKSSNNDNDKDSD 745
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
20-196 |
1.89e-11 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 65.49 E-value: 1.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRtegsvyylpqileqFDTQSIARalgvqkkLSAlREILEG 99
Cdd:PRK10851 20 DISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIR--------------FHGTDVSR-------LHA-RDRKVG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 100 IVTE-----ENITVLD---------------DNWDLEEKIKQALETWGLlDFTADESMNRLSGGQKTKVLIAGIEIHQPD 159
Cdd:PRK10851 78 FVFQhyalfRHMTVFDniafgltvlprrerpNAAAIKAKVTQLLEMVQL-AHLADRYPAQLSGGQKQRVALARALAVEPQ 156
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 639228517 160 IILMDEPTNHLDRQSREQLYEFIENTNKTL----LVVSHDR 196
Cdd:PRK10851 157 ILLLDEPFGALDAQVRKELRRWLRQLHEELkftsVFVTHDQ 197
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
18-195 |
2.15e-11 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 62.83 E-value: 2.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 18 FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileQFDTQSIARALGVqkklsalreil 97
Cdd:cd03215 16 VRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPV-------TRRSPRDAIRAGI----------- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 98 eGIVTEEnitvlddnwdleeKIKQALetwgLLDFTADESM---NRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQS 174
Cdd:cd03215 78 -AYVPED-------------RKREGL----VLDLSVAENIalsSLLSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGA 139
|
170 180
....*....|....*....|....
gi 639228517 175 REQLYEFIE---NTNKTLLVVSHD 195
Cdd:cd03215 140 KAEIYRLIRelaDAGKAVLLISSE 163
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
338-512 |
2.25e-11 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 63.78 E-value: 2.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeradfnsvYID-QDYSMINHSL 416
Cdd:cd03254 3 IEFENVNFSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQI--------LIDgIDIRDISRKS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 417 ------SVIQQAESFNwlplpehevKTILSRFLFGKET-----WDKSC------------------------SVLSGGER 461
Cdd:cd03254 75 lrsmigVVLQDTFLFS---------GTIMENIRLGRPNatdeeVIEAAkeagahdfimklpngydtvlgengGNLSQGER 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 639228517 462 MRLLLACLSItgKAPDIIILDEPTNNLDLQNIEILTNAIRD-YKG-TLLVISH 512
Cdd:cd03254 146 QLLAIARAML--RDPKILILDEATSNIDTETEKLIQEALEKlMKGrTSIIIAH 196
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
337-513 |
2.32e-11 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 63.61 E-value: 2.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDK----NIWKkPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-------------ERAD 399
Cdd:COG4181 8 IIELRGLTKTVGTGagelTILK-GISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVrlagqdlfaldedARAR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 400 FNSvyidqdysminHSLSVIQQaeSFNWLP---------LP-----EHEVKTILSRFL--FG-KETWDKSCSVLSGGERM 462
Cdd:COG4181 87 LRA-----------RHVGFVFQ--SFQLLPtltalenvmLPlelagRRDARARARALLerVGlGHRLDHYPAQLSGGEQQ 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 463 RLLLACLSITGkaPDIIILDEPTNNLDLQN----IEILTNAIRDYKGTLLVISHD 513
Cdd:COG4181 154 RVALARAFATE--PAILFADEPTGNLDAATgeqiIDLLFELNRERGTTLVLVTHD 206
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
9-195 |
2.47e-11 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 64.30 E-value: 2.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 9 YQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQILEQFDTQSIARALGV-- 86
Cdd:PRK14246 17 YLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYFGKDIFQIDAIKLRKEVGMvf 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 87 -QKKLSALREILEGIVTEENITVLDDNWDLEEKIKQALETWGLLDFTADE---SMNRLSGGQKTKVLIAGIEIHQPDIIL 162
Cdd:PRK14246 97 qQPNPFPHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLWKEVYDRlnsPASQLSGGQQQRLTIARALALKPKVLL 176
|
170 180 190
....*....|....*....|....*....|....*
gi 639228517 163 MDEPTNHLDRQSREQLYEFIENTNK--TLLVVSHD 195
Cdd:PRK14246 177 MDEPTSMIDIVNSQAIEKLITELKNeiAIVIVSHN 211
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
20-194 |
2.58e-11 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 65.82 E-value: 2.58e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileQFDTQSIARALGV----Q-----KKL 90
Cdd:COG3845 23 DVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPV-------RIRSPRDAIALGIgmvhQhfmlvPNL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 91 SALreilegivteENITV-LDDNW-------DLEEKIKQALETWGL-LDftADESMNRLSGGQKTKVliagiEI-----H 156
Cdd:COG3845 96 TVA----------ENIVLgLEPTKggrldrkAARARIRELSERYGLdVD--PDAKVEDLSVGEQQRV-----EIlkalyR 158
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 639228517 157 QPDIILMDEPTNHLDRQSREQLYEFIEN---TNKTLLVVSH 194
Cdd:COG3845 159 GARILILDEPTAVLTPQEADELFEILRRlaaEGKSIIFITH 199
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
336-513 |
2.74e-11 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 63.94 E-value: 2.74e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 336 ILIKAEHINHAYQ-----DKNIWKKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI------------ 395
Cdd:PRK10419 2 TLLNVSGLSHHYAhgglsGKHQHQTVLNNVslsLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVswrgeplaklnr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 396 -ERADFNsvyidQDYSMinhslsVIQQAES-FNwlplPEHEVKTILS---RFLFG--------------------KETWD 450
Cdd:PRK10419 82 aQRKAFR-----RDIQM------VFQDSISaVN----PRKTVREIIReplRHLLSldkaerlarasemlravdldDSVLD 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 451 KSCSVLSGGERMRLLLA-CLSITgkaPDIIILDEPTNNLDL----QNIEILTnAIRDYKGT-LLVISHD 513
Cdd:PRK10419 147 KRPPQLSGGQLQRVCLArALAVE---PKLLILDEAVSNLDLvlqaGVIRLLK-KLQQQFGTaCLFITHD 211
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
6-521 |
2.75e-11 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 66.03 E-value: 2.75e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 6 NITYQHPDKEI-LFENLNFIVNKGDKIAIVGNNGSGKS-TLLKLISgLLTPSAGDIRTEgsvyylPQILEQFDTQSIARA 83
Cdd:PRK10261 19 NIAFMQEQQKIaAVRNLSFSLQRGETLAIVGESGSGKSvTALALMR-LLEQAGGLVQCD------KMLLRRRSRQVIELS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 84 LGVQKKLSALREILEGIVTEENITVLDDNWDLEEKIKQAL-------------ETWGLLDFT----ADESMNR----LSG 142
Cdd:PRK10261 92 EQSAAQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIrlhqgasreeamvEAKRMLDQVripeAQTILSRyphqLSG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 143 GQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTL----LVVSHDRTLLnllpktAELSRKEMMLYGG 218
Cdd:PRK10261 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMsmgvIFITHDMGVV------AEIADRVLVMYQG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 219 NYDSYKEQKQIQQNALQNSIKNTENALKKAKATERETLERqqkldakgkkkqekagvaKIMMNTLRNNAENSTAKIRDTH 298
Cdd:PRK10261 246 EAVETGSVEQIFHAPQHPYTRALLAAVPQLGAMKGLDYPR------------------RFPLISLEHPAKQEPPIEQDTV 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 299 SDkieglSQELQQLRRGV---PLtdqmklgfdqanlhRGKILIKAEHINHAYQDK--NIWkkpldvvvsSGERILIIGEN 373
Cdd:PRK10261 308 VD-----GEPILQVRNLVtrfPL--------------RSGLLNRVTREVHAVEKVsfDLW---------PGETLSLVGES 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 374 GSGKTTLIKLLLGQMKPSEGTI----ERADFNSV-----------YIDQD-YSMINHSLSV---IQQaesfnwlPLPEH- 433
Cdd:PRK10261 360 GSGKSTTGRALLRLVESQGGEIifngQRIDTLSPgklqalrrdiqFIFQDpYASLDPRQTVgdsIME-------PLRVHg 432
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 434 ---------EVKTILSRFLFGKETWDKSCSVLSGGERMRLLLA-CLSITgkaPDIIILDEPTNNLDL----QNIEILTNA 499
Cdd:PRK10261 433 llpgkaaaaRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIArALALN---PKVIIADEAVSALDVsirgQIINLLLDL 509
|
570 580
....*....|....*....|..
gi 639228517 500 IRDYKGTLLVISHDDVFSEEIN 521
Cdd:PRK10261 510 QRDFGIAYLFISHDMAVVERIS 531
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
361-520 |
3.04e-11 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 65.96 E-value: 3.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI------------------ERADFNSVyIDQD--YSMINHSLSVIQ 420
Cdd:PRK10636 24 INPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYtfpgnwqlawvnqetpalPQPALEYV-IDGDreYRQLEAQLHDAN 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 421 QAESFNWLPLPEHEVKTI------------LSRFLFGKETWDKSCSVLSGGERMRLLLA----CLSitgkapDIIILDEP 484
Cdd:PRK10636 103 ERNDGHAIATIHGKLDAIdawtirsraaslLHGLGFSNEQLERPVSDFSGGWRMRLNLAqaliCRS------DLLLLDEP 176
|
170 180 190
....*....|....*....|....*....|....*.
gi 639228517 485 TNNLDLQNIEILTNAIRDYKGTLLVISHDDVFSEEI 520
Cdd:PRK10636 177 TNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPI 212
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
337-513 |
3.07e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 64.10 E-value: 3.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI----------------ERADF 400
Cdd:PRK13636 5 ILKVEELNYNYSDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRIlfdgkpidysrkglmkLRESV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 401 NSVYIDQDYSMInhSLSVIQQAeSFNW--LPLPEHEVKTILSRFLfgKETW-----DKSCSVLSGGERMRLLLAclSITG 473
Cdd:PRK13636 85 GMVFQDPDNQLF--SASVYQDV-SFGAvnLKLPEDEVRKRVDNAL--KRTGiehlkDKPTHCLSFGQKKRVAIA--GVLV 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 639228517 474 KAPDIIILDEPTNNLDLQNI----EILTNAIRDYKGTLLVISHD 513
Cdd:PRK13636 158 MEPKVLVLDEPTAGLDPMGVseimKLLVEMQKELGLTIIIATHD 201
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
337-513 |
3.56e-11 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 63.67 E-value: 3.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQD-----KNIWKKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE------------ 396
Cdd:TIGR02769 2 LLEVRDVTHTYRTgglfgAKQRAPVLTNVslsIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSfrgqdlyqldrk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 397 -----RADFNSVYIDQdYSMINHSLSVIQQ-AESF-NWLPLPEHEVKTILSRFL----FGKETWDKSCSVLSGGERMRLL 465
Cdd:TIGR02769 82 qrrafRRDVQLVFQDS-PSAVNPRMTVRQIiGEPLrHLTSLDESEQKARIAELLdmvgLRSEDADKLPRQLSGGQLQRIN 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 639228517 466 LA-CLSITgkaPDIIILDEPTNNLDLQN----IEILTnAIRDYKGT-LLVISHD 513
Cdd:TIGR02769 161 IArALAVK---PKLIVLDEAVSNLDMVLqaviLELLR-KLQQAFGTaYLFITHD 210
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
338-489 |
4.38e-11 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 62.60 E-value: 4.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKkPLDVVVSSGERILIiGENGSGKTTLIKLLLGQMKPSEGTIERADFNSV-----------YID 406
Cdd:cd03264 1 LQLENLTKRYGKKRALD-GVSLTLGPGMYGLL-GPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLkqpqklrrrigYLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 407 QDYSMINHsLSVIQQAESFNWL-----PLPEHEVKTILSRFLFGkETWDKSCSVLSGGERMRLLLAClSITGKaPDIIIL 481
Cdd:cd03264 79 QEFGVYPN-FTVREFLDYIAWLkgipsKEVKARVDEVLELVNLG-DRAKKKIGSLSGGMRRRVGIAQ-ALVGD-PSILIV 154
|
....*...
gi 639228517 482 DEPTNNLD 489
Cdd:cd03264 155 DEPTAGLD 162
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
19-194 |
4.43e-11 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 65.19 E-value: 4.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVY--YLPQILEQFDTQSIARALGVQKKLSALREI 96
Cdd:PRK09700 22 KSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYnkLDHKLAAQLGIGIIYQELSVIDELTVLENL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 97 LEG-IVTEENITVLDDNWDlEEKIKQALETWGL-LDFTADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQS 174
Cdd:PRK09700 102 YIGrHLTKKVCGVNIIDWR-EMRVRAAMMLLRVgLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKE 180
|
170 180
....*....|....*....|...
gi 639228517 175 REQLYEFI---ENTNKTLLVVSH 194
Cdd:PRK09700 181 VDYLFLIMnqlRKEGTAIVYISH 203
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
361-502 |
4.46e-11 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 62.97 E-value: 4.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI----------ERADFNSV-----YIDQDYSMINHsLSVIQQAES- 424
Cdd:cd03256 24 INPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVlidgtdinklKGKALRQLrrqigMIFQQFNLIER-LSVLENVLSg 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 425 -----------FNWLPLPEHEV-KTILSRF-LFGKETwdKSCSVLSGGERMRLLLA-CLSitgKAPDIIILDEPTNNLDL 490
Cdd:cd03256 103 rlgrrstwrslFGLFPKEEKQRaLAALERVgLLDKAY--QRADQLSGGQQQRVAIArALM---QQPKLILADEPVASLDP 177
|
170
....*....|..
gi 639228517 491 QNIEILTNAIRD 502
Cdd:cd03256 178 ASSRQVMDLLKR 189
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1-195 |
5.82e-11 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 62.80 E-value: 5.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQIleqfDTQSI 80
Cdd:PRK09493 1 MIEFKNVSKHFGPTQVL-HNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKV----DERLI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGV--QK-----KLSALREILEGIVTEENITvlddNWDLEEKIKQALETWGLLDfTADESMNRLSGGQKTKVLIAGI 153
Cdd:PRK09493 76 RQEAGMvfQQfylfpHLTALENVMFGPLRVRGAS----KEEAEKQARELLAKVGLAE-RAHHYPSELSGGQQQRVAIARA 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 639228517 154 EIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHD 195
Cdd:PRK09493 151 LAVKPKLMLFDEPTSALDPELRHEVLKVMQdlaEEGMTMVIVTHE 195
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
357-516 |
7.09e-11 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 61.74 E-value: 7.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE---------RADFNS--VYIDQdYSMINHSLSVIqqaESF 425
Cdd:PRK13538 20 LSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLwqgepirrqRDEYHQdlLYLGH-QPGIKTELTAL---ENL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 426 NWL-----PLPEHEVKTILSRF-LFGKEtwDKSCSVLSGGERMRLLLACLSITgKAPdIIILDEPTNNLDLQNIEILTNA 499
Cdd:PRK13538 96 RFYqrlhgPGDDEALWEALAQVgLAGFE--DVPVRQLSAGQQRRVALARLWLT-RAP-LWILDEPFTAIDKQGVARLEAL 171
|
170 180
....*....|....*....|
gi 639228517 500 IRDY---KGTLLVISHDDVF 516
Cdd:PRK13538 172 LAQHaeqGGMVILTTHQDLP 191
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
360-522 |
7.10e-11 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 64.83 E-value: 7.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 360 VVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIER-ADFNSVyID-------QDY--SMINHSLSVIQQAESFNWLP 429
Cdd:PRK13409 95 IPKEGKVTGILGPNGIGKTTAVKILSGELIPNLGDYEEePSWDEV-LKrfrgtelQNYfkKLYNGEIKVVHKPQYVDLIP 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 430 -------------LPEHEVKTILSRFLFGKETWDKSCSVLSGGERMRLLL-ACLSitgKAPDIIILDEPTNNLDL-QNIE 494
Cdd:PRK13409 174 kvfkgkvrellkkVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIaAALL---RDADFYFFDEPTSYLDIrQRLN 250
|
170 180 190
....*....|....*....|....*....|....
gi 639228517 495 IlTNAIRDY--KGTLLVISHD----DVFSEEINI 522
Cdd:PRK13409 251 V-ARLIRELaeGKYVLVVEHDlavlDYLADNVHI 283
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
4-194 |
8.69e-11 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 64.27 E-value: 8.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 4 LQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPS-AGDI----RTEGSVYYLPQILEQFDTQ 78
Cdd:PRK10938 263 LNNGVVSYNDRPIL-HNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGySNDLtlfgRRRGSGETIWDIKKHIGYV 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 SIARALGVQKKLSALREILEGIVTEENI--TVLDdnwDLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIH 156
Cdd:PRK10938 342 SSSLHLDYRVSTSVRNVILSGFFDSIGIyqAVSD---RQQKLAQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVK 418
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 639228517 157 QPDIILMDEPTNHLDRQSREQLYEFIE----NTNKTLLVVSH 194
Cdd:PRK10938 419 HPTLLILDEPLQGLDPLNRQLVRRFVDvlisEGETQLLFVSH 460
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
337-513 |
8.89e-11 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 61.50 E-value: 8.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQdKNIWK-KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYID--------- 406
Cdd:TIGR02673 1 MIEFHNVSKAYP-GGVAAlHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRgrqlpllrr 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 407 ------QDYSMINH---------SLSVIQQAEsfnwlPLPEHEVKTILsRFLFGKETWDKSCSVLSGGERMRLLLAcLSI 471
Cdd:TIGR02673 80 rigvvfQDFRLLPDrtvyenvalPLEVRGKKE-----REIQRRVGAAL-RQVGLEHKADAFPEQLSGGEQQRVAIA-RAI 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 639228517 472 TGKaPDIIILDEPTNNLDLQN---IEILTNAIRDYKGTLLVISHD 513
Cdd:TIGR02673 153 VNS-PPLLLADEPTGNLDPDLserILDLLKRLNKRGTTVIVATHD 196
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-209 |
8.97e-11 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 62.36 E-value: 8.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISgLLTPSAGDIRTEGSVyylpqileQFDTQSIA 81
Cdd:PRK14258 8 IKVNNLSFYYDTQKIL-EGVSMEIYQSKVTAIIGPSGCGKSTFLKCLN-RMNELESEVRVEGRV--------EFFNQNIY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RAlgvQKKLSALREILEGIVTEENI---TVLDD--------NW-------DLEEKIKQALETWGLLDFTADESMNRLSGG 143
Cdd:PRK14258 78 ER---RVNLNRLRRQVSMVHPKPNLfpmSVYDNvaygvkivGWrpkleidDIVESALKDADLWDEIKHKIHKSALDLSGG 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 144 QKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN----TNKTLLVVSHDrtllnlLPKTAELS 209
Cdd:PRK14258 155 QQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSlrlrSELTMVIVSHN------LHQVSRLS 218
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
338-513 |
9.47e-11 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 61.81 E-value: 9.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLL-----LGQMKPSEGTIERADFNsVYiDQDYSMI 412
Cdd:cd03260 1 IELRDLNVYYGDKHALKD-ISLDIPKGEITALIGPSGCGKSTLLRLLnrlndLIPGAPDEGEVLLDGKD-IY-DLDVDVL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 413 NHSLS---VIQQAESFNW-------LPLPEH----------EVKTILSRFLFGKETWDK-SCSVLSGGERMRLLLA-CLS 470
Cdd:cd03260 78 ELRRRvgmVFQKPNPFPGsiydnvaYGLRLHgiklkeeldeRVEEALRKAALWDEVKDRlHALGLSGGQQQRLCLArALA 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 639228517 471 ItgkAPDIIILDEPTNNLDLQNIEILTNAIRDYKG--TLLVISHD 513
Cdd:cd03260 158 N---EPEVLLLDEPTSALDPISTAKIEELIAELKKeyTIVIVTHN 199
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
3-197 |
9.60e-11 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 63.51 E-value: 9.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 3 TLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDI--------------RTEGSV--- 65
Cdd:PRK11000 5 TLRNVTKAYGDVVIS-KDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLfigekrmndvppaeRGVGMVfqs 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 66 YYLPQILEQFDTQSIARALGVQKKlsalREIlegivteenitvlddnwdlEEKIKQALETWGLlDFTADESMNRLSGGQK 145
Cdd:PRK11000 84 YALYPHLSVAENMSFGLKLAGAKK----EEI-------------------NQRVNQVAEVLQL-AHLLDRKPKALSGGQR 139
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHDRT 197
Cdd:PRK11000 140 QRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRIEISRLHKrlgrTMIYVTHDQV 195
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
2-60 |
9.72e-11 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 64.05 E-value: 9.72e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639228517 2 LTLQNITYQHPDKEI--LFE--NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIR 60
Cdd:COG4615 328 LELRGVTYRYPGEDGdeGFTlgPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEIL 390
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
335-513 |
9.77e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 62.32 E-value: 9.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 335 KILIKAEHINHAY-QDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERadFNSVYIDQDYSMIN 413
Cdd:PRK13632 5 SVMIKVENVSFSYpNSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKI--DGITISKENLKEIR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 414 HSLSVIQQ---------------AESFNWLPLPEHEVKTI---LSRFLFGKETWDKSCSVLSGGERMRLLLAclSITGKA 475
Cdd:PRK13632 83 KKIGIIFQnpdnqfigatveddiAFGLENKKVPPKKMKDIiddLAKKVGMEDYLDKEPQNLSGGQKQRVAIA--SVLALN 160
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 639228517 476 PDIIILDEPTNNLDLQN----IEILTNAIRDYKGTLLVISHD 513
Cdd:PRK13632 161 PEIIIFDESTSMLDPKGkreiKKIMVDLRKTRKKTLISITHD 202
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
2-202 |
9.77e-11 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 61.47 E-value: 9.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIvnkgdkiaIVGNNGSGKSTLLKLISGLLTPSA----------GDIRTEGSVyyLPQI 71
Cdd:cd03240 4 LSIRNIRSFHERSEIEFFSPLTL--------IVGQNGAGKTTIIEALKYALTGELppnskggahdPKLIREGEV--RAQV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 72 LEQFdTQSIARALGVQKKLSALREILegIVTEENItvlddNWDLEEKIKqaletwglldftadesmnRLSGGQKTKVLIA 151
Cdd:cd03240 74 KLAF-ENANGKKYTITRSLAILENVI--FCHQGES-----NWPLLDMRG------------------RCSGGEKVLASLI 127
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 152 ---------GIEIhqpDIILMDEPTNHLDRQSRE-QLYEFIENTNKT----LLVVSHDRTLLNLL 202
Cdd:cd03240 128 irlalaetfGSNC---GILALDEPTTNLDEENIEeSLAEIIEERKSQknfqLIVITHDEELVDAA 189
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
338-519 |
1.05e-10 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 62.90 E-value: 1.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI--------ERADF--NSVYIDQ 407
Cdd:PRK13537 8 IDFRNVEKRYGDKLVVDG-LSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSIslcgepvpSRARHarQRVGVVP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 408 DYSMINHSLSVIQQAESFN-WLPLPEHEVKTILSRFL-FGK--ETWDKSCSVLSGGERMRLLLACLSITGkaPDIIILDE 483
Cdd:PRK13537 87 QFDNLDPDFTVRENLLVFGrYFGLSAAAARALVPPLLeFAKleNKADAKVGELSGGMKRRLTLARALVND--PDVLVLDE 164
|
170 180 190
....*....|....*....|....*....|....*....
gi 639228517 484 PTNNLDLQNIEILTNAIRDY--KG-TLLVISHddvFSEE 519
Cdd:PRK13537 165 PTTGLDPQARHLMWERLRSLlaRGkTILLTTH---FMEE 200
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
338-513 |
1.17e-10 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 61.95 E-value: 1.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradfnsvYIDQDYSMinhsLS 417
Cdd:PRK11231 3 LRTENLTVGYGTKRILND-LSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVF-------LGDKPISM----LS 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 418 VIQQAESFNWLP--LPEHEVKTILSRFLFGKETW----------------------------DKSCSVLSGGERMRLLLA 467
Cdd:PRK11231 71 SRQLARRLALLPqhHLTPEGITVRELVAYGRSPWlslwgrlsaednarvnqameqtrinhlaDRRLTDLSGGQRQRAFLA 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 639228517 468 cLSITGKAPdIIILDEPTNNLDLQNIEILTNAIRDYKG---TLLVISHD 513
Cdd:PRK11231 151 -MVLAQDTP-VVLLDEPTTYLDINHQVELMRLMRELNTqgkTVVTVLHD 197
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
1-171 |
1.21e-10 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 61.40 E-value: 1.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEIlFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqilEQFDTQSI 80
Cdd:PRK13543 11 LLAAHALAFSRNEEPV-FGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDG---------KTATRGDR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGVQKKLSALREILEgivTEENITVLD--DNWDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQP 158
Cdd:PRK13543 81 SRFMAYLGHLPGLKADLS---TLENLHFLCglHGRRAKQMPGSALAIVGLAGY-EDTLVRQLSAGQKKRLALARLWLSPA 156
|
170
....*....|...
gi 639228517 159 DIILMDEPTNHLD 171
Cdd:PRK13543 157 PLWLLDEPYANLD 169
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
368-521 |
1.37e-10 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 60.70 E-value: 1.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 368 LIIGENGSGKTTLIKLLL----GQMKP-SEGTIERADF-----NSVYIDQDYSMIN-------HSLSVIQQA-----ESF 425
Cdd:cd03240 26 LIVGQNGAGKTTIIEALKyaltGELPPnSKGGAHDPKLiregeVRAQVKLAFENANgkkytitRSLAILENVifchqGES 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 426 NWlPLPEHEVKtilsrflfgketwdkscsvLSGGERMrllLACLSIT-------GKAPDIIILDEPTNNLDLQNIEI-LT 497
Cdd:cd03240 106 NW-PLLDMRGR-------------------CSGGEKV---LASLIIRlalaetfGSNCGILALDEPTTNLDEENIEEsLA 162
|
170 180
....*....|....*....|....*...
gi 639228517 498 NAIRDYKGT----LLVISHDDVFSEEIN 521
Cdd:cd03240 163 EIIEERKSQknfqLIVITHDEELVDAAD 190
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
338-489 |
1.49e-10 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 61.40 E-value: 1.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-------------ERADFNSVY 404
Cdd:cd03218 1 LRAENLSKRYGKRKVVNG-VSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKIlldgqditklpmhKRARLGIGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 405 IDQDYSmINHSLSVIQQAES-FNWLPLPEHEVKTILSRFL--FG-KETWDKSCSVLSGGERMRLLLACLSITGkaPDIII 480
Cdd:cd03218 80 LPQEAS-IFRKLTVEENILAvLEIRGLSKKEREEKLEELLeeFHiTHLRKSKASSLSGGERRRVEIARALATN--PKFLL 156
|
....*....
gi 639228517 481 LDEPTNNLD 489
Cdd:cd03218 157 LDEPFAGVD 165
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
357-514 |
1.56e-10 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 61.33 E-value: 1.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-------------ERADF---NSVYIDQDYSMI-------N 413
Cdd:PRK10584 29 VELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVslvgqplhqmdeeARAKLrakHVGFVFQSFMLIptlnaleN 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 414 HSLSVIQQAESFNWlplPEHEVKTILSRFLFGKETwDKSCSVLSGGERMRLLLAcLSITGKaPDIIILDEPTNNLDLQN- 492
Cdd:PRK10584 109 VELPALLRGESSRQ---SRNGAKALLEQLGLGKRL-DHLPAQLSGGEQQRVALA-RAFNGR-PDVLFADEPTGNLDRQTg 182
|
170 180
....*....|....*....|....*
gi 639228517 493 ---IEILTNAIRDYKGTLLVISHDD 514
Cdd:PRK10584 183 dkiADLLFSLNREHGTTLILVTHDL 207
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
2-194 |
1.83e-10 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 63.01 E-value: 1.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyyLPQileQFDTQSIA 81
Cdd:PRK11288 5 LSFDGIGKTFPGVKAL-DDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDG----QEM---RFASTTAA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGVQKKLSALREILEGIVTeENITV--------LDDNWDLEEKIKQALETWGlLDFTADESMNRLSGGQKTKVLIAGI 153
Cdd:PRK11288 77 LAAGVAIIYQELHLVPEMTVA-ENLYLgqlphkggIVNRRLLNYEAREQLEHLG-VDIDPDTPLKYLSIGQRQMVEIAKA 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 639228517 154 EIHQPDIILMDEPTNHLDRQSREQLYEFIEN---TNKTLLVVSH 194
Cdd:PRK11288 155 LARNARVIAFDEPTSSLSAREIEQLFRVIRElraEGRVILYVSH 198
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
5-196 |
1.87e-10 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 63.21 E-value: 1.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 5 QNITYQHPDKeILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVyylpqileqfdtqsiaral 84
Cdd:PRK11819 328 ENLSKSFGDR-LLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIGETV------------------- 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 85 gvqkKLSAL---REILEGivteeNITVlddnWdleEKIKQALETWGLLDFT--------------ADES--MNRLSGGQK 145
Cdd:PRK11819 388 ----KLAYVdqsRDALDP-----NKTV----W---EEISGGLDIIKVGNREipsrayvgrfnfkgGDQQkkVGVLSGGER 451
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTLLVVSHDR 196
Cdd:PRK11819 452 NRLHLAKTLKQGGNVLLLDEPTNDLDVETLRALEEALLEFPGCAVVISHDR 502
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
369-513 |
2.10e-10 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 61.31 E-value: 2.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 369 IIGENGSGKTTLIKLLLGQMKPSEGTIEradFNSVYID-QDYSMINHSLSVIQQ---------------AESFNWLPLPE 432
Cdd:PRK13648 40 IVGHNGSGKSTIAKLMIGIEKVKSGEIF---YNNQAITdDNFEKLRKHIGIVFQnpdnqfvgsivkydvAFGLENHAVPY 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 433 HEVKTILSRFLFGKETWDKSCS---VLSGGERMRLLLAclSITGKAPDIIILDEPTNNLDLQNIEILTNAIRDYKG---- 505
Cdd:PRK13648 117 DEMHRRVSEALKQVDMLERADYepnALSGGQKQRVAIA--GVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSehni 194
|
....*...
gi 639228517 506 TLLVISHD 513
Cdd:PRK13648 195 TIISITHD 202
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
357-520 |
2.43e-10 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 60.92 E-value: 2.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADfnsVYIDQDYSmINHSLSVIQQA--------ESFNWL 428
Cdd:PRK11264 22 IDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGD---ITIDTARS-LSQQKGLIRQLrqhvgfvfQNFNLF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 429 P-----------------LPEHEV----KTILSRF-LFGKEtwDKSCSVLSGGERMRLLLA-CLSITgkaPDIIILDEPT 485
Cdd:PRK11264 98 PhrtvleniiegpvivkgEPKEEAtaraRELLAKVgLAGKE--TSYPRRLSGGQQQRVAIArALAMR---PEVILFDEPT 172
|
170 180 190
....*....|....*....|....*....|....*...
gi 639228517 486 NNLDLQNIEILTNAIR---DYKGTLLVISHDDVFSEEI 520
Cdd:PRK11264 173 SALDPELVGEVLNTIRqlaQEKRTMVIVTHEMSFARDV 210
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
357-509 |
2.69e-10 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 60.53 E-value: 2.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-------------ERADFNSVYIDQDySMINHSLSV---IQ 420
Cdd:cd03224 19 VSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIrfdgrditglpphERARAGIGYVPEG-RRIFPELTVeenLL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 421 QAESFNWLPLPEHEVKTILSRF--LfgKETWDKSCSVLSGGER-MrlllacLSItGKA----PDIIILDEPTNNLDLQNI 493
Cdd:cd03224 98 LGAYARRRAKRKARLERVYELFprL--KERRKQLAGTLSGGEQqM------LAI-ARAlmsrPKLLLLDEPSEGLAPKIV 168
|
170 180
....*....|....*....|
gi 639228517 494 EILTNAIRDYKGT----LLV 509
Cdd:cd03224 169 EEIFEAIRELRDEgvtiLLV 188
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
357-513 |
3.03e-10 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 60.82 E-value: 3.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradFNsvyiDQDYS-----MINH--------------SLS 417
Cdd:COG0411 23 VSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRIL---FD----GRDITglpphRIARlgiartfqnprlfpELT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 418 VI---------QQAESF--NWLPLP---------EHEVKTILSRFLFGKEtWDKSCSVLSGGERMRLLLACLSITGkaPD 477
Cdd:COG0411 96 VLenvlvaahaRLGRGLlaALLRLPrarreereaRERAEELLERVGLADR-ADEPAGNLSYGQQRRLEIARALATE--PK 172
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 639228517 478 IIILDEPTNNLDLQNIEILTNAIRDYKG----TLLVISHD 513
Cdd:COG0411 173 LLLLDEPAAGLNPEETEELAELIRRLRDergiTILLIEHD 212
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
21-198 |
3.41e-10 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 60.33 E-value: 3.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 21 LNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSagdirteGSVYYLPQILEQFDTQSIA--RA-LGVQKKLSALREIL 97
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLLPGS-------GSIQFAGQPLEAWSAAELArhRAyLSQQQTPPFAMPVF 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 98 --------EGIVTEENITVLDDnwdleekIKQALetwGLLDFTAdESMNRLSGGQKTKVLIAGI--EIHqPDI------I 161
Cdd:PRK03695 88 qyltlhqpDKTRTEAVASALNE-------VAEAL---GLDDKLG-RSVNQLSGGEWQRVRLAAVvlQVW-PDInpagqlL 155
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 639228517 162 LMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSHD--RTL 198
Cdd:PRK03695 156 LLDEPMNSLDVAQQAALDRLLSelcQQGIAVVMSSHDlnHTL 197
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
356-395 |
3.83e-10 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 62.12 E-value: 3.83e-10
10 20 30 40
....*....|....*....|....*....|....*....|
gi 639228517 356 PLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI 395
Cdd:COG4615 350 PIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEI 389
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1-189 |
3.93e-10 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 61.36 E-value: 3.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNI--TYQHPDKEIL-FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpQILEQFDt 77
Cdd:PRK11153 1 MIELKNIskVFPQGGRTIHaLNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDG------QDLTALS- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 qsiaralgvQKKLSALREILEGIVTEENI----TVLD--------DNWDlEEKIKQA----LETWGLLDFtADESMNRLS 141
Cdd:PRK11153 74 ---------EKELRKARRQIGMIFQHFNLlssrTVFDnvalplelAGTP-KAEIKARvtelLELVGLSDK-ADRYPAQLS 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 142 GGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKTL 189
Cdd:PRK11153 143 GGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINREL 190
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
13-194 |
4.79e-10 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 60.05 E-value: 4.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 13 DKEILFeNLNFIVNKGDKIAIVGNNGSGKSTLLKLISGL--LTPSAgdiRTEGSVYylpqileqFDTQSIaraLGVQKKL 90
Cdd:COG1117 23 DKQALK-DINLDIPENKVTALIGPSGCGKSTLLRCLNRMndLIPGA---RVEGEIL--------LDGEDI---YDPDVDV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 91 SALR-EIleGIVTE----------ENIT-------VLDDNwDLEEKIKQALETWGLLDFTAD---ESMNRLSGGQKTKVL 149
Cdd:COG1117 88 VELRrRV--GMVFQkpnpfpksiyDNVAyglrlhgIKSKS-ELDEIVEESLRKAALWDEVKDrlkKSALGLSGGQQQRLC 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 150 IA-GIEIhQPDIILMDEPTNHLDRQSREQLYEFIEN--TNKTLLVVSH 194
Cdd:COG1117 165 IArALAV-EPEVLLMDEPTSALDPISTAKIEELILElkKDYTIVIVTH 211
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
361-513 |
6.32e-10 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 61.69 E-value: 6.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeRADFNSVY-IDQDysminhslsviQQAESFNWLP---------- 429
Cdd:COG4618 355 LEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSV-RLDGADLSqWDRE-----------ELGRHIGYLPqdvelfdgti 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 430 ------LPE---------------HEvkTILsRFLFGKETW-DKSCSVLSGGERMRLLLAclsitgKA----PDIIILDE 483
Cdd:COG4618 423 aeniarFGDadpekvvaaaklagvHE--MIL-RLPDGYDTRiGEGGARLSGGQRQRIGLA------RAlygdPRLVVLDE 493
|
170 180 190
....*....|....*....|....*....|...
gi 639228517 484 PTNNLDLQNIEILTNAIRDYK---GTLLVISHD 513
Cdd:COG4618 494 PNSNLDDEGEAALAAAIRALKargATVVVITHR 526
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
360-513 |
7.47e-10 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 58.35 E-value: 7.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 360 VVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQDYSminhslsviqqaesfnwlplpehevktil 439
Cdd:cd03222 21 VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITPVYKPQYID----------------------------- 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 440 srflfgketwdkscsvLSGGERMRLLLA-CLsitGKAPDIIILDEPTNNLDLQNIEILTNAIRDY----KGTLLVISHD 513
Cdd:cd03222 72 ----------------LSGGELQRVAIAaAL---LRNATFYLFDEPSAYLDIEQRLNAARAIRRLseegKKTALVVEHD 131
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
2-217 |
8.98e-10 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 59.14 E-value: 8.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDI--------------RTEGSVYY 67
Cdd:PRK10895 4 LTAKNLAKAYKGRRVV-EDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIiiddedisllplhaRARRGIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 68 LPQileqfdTQSIARALGVQKKLSALREILEGIVTEENitvlddnwdlEEKIKQALETWGLLDFTaDESMNRLSGGQKTK 147
Cdd:PRK10895 83 LPQ------EASIFRRLSVYDNLMAVLQIRDDLSAEQR----------EDRANELMEEFHIEHLR-DSMGQSLSGGERRR 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639228517 148 VLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKT---LLVVSHD-RTLLNLLPKTAELSRKEMMLYG 217
Cdd:PRK10895 146 VEIARALAANPKFILLDEPFAGVDPISVIDIKRIIEHLRDSglgVLITDHNvRETLAVCERAYIVSQGHLIAHG 219
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
2-195 |
1.12e-09 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 59.51 E-value: 1.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS----------VYYLPQI 71
Cdd:PRK15056 7 IVVNDVTVTWRNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQptrqalqknlVAYVPQS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 72 lEQFD------TQSIArALGVQKKLSALReilegIVTEENITVLDDnwdleekikqALETWGLLDFTADEsMNRLSGGQK 145
Cdd:PRK15056 87 -EEVDwsfpvlVEDVV-MMGRYGHMGWLR-----RAKKRDRQIVTA----------ALARVDMVEFRHRQ-IGELSGGQK 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEF---IENTNKTLLVVSHD 195
Cdd:PRK15056 149 KRVFLARAIAQQGQVILLDEPFTGVDVKTEARIISLlreLRDEGKTMLVSTHN 201
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
343-489 |
1.24e-09 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 59.84 E-value: 1.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 343 INHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE----------RADFNSVYIDQDYSMI 412
Cdd:PRK13536 47 VSKSYGDKAVVNG-LSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITvlgvpvparaRLARARIGVVPQFDNL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 413 NHSLSVIQQAESFN-WLPLPEHEVKTILSRFL-FGK--ETWDKSCSVLSGGERMRLLLACLSITGkaPDIIILDEPTNNL 488
Cdd:PRK13536 126 DLEFTVRENLLVFGrYFGMSTREIEAVIPSLLeFARleSKADARVSDLSGGMKRRLTLARALIND--PQLLILDEPTTGL 203
|
.
gi 639228517 489 D 489
Cdd:PRK13536 204 D 204
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
342-515 |
1.31e-09 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 58.04 E-value: 1.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 342 HINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradFNSVYIDQDYSMINHSLSVIQQ 421
Cdd:PRK13540 6 ELDFDYHDQPLLQQ-ISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEIL---FERQSIKKDLCTYQKQLCFVGH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 422 AESFN-WLPLPEH------------EVKTILSRFLFGkETWDKSCSVLSGGERMRLLLACLSITGKapDIIILDEPTNNL 488
Cdd:PRK13540 82 RSGINpYLTLRENclydihfspgavGITELCRLFSLE-HLIDYPCGLLSSGQKRQVALLRLWMSKA--KLWLLDEPLVAL 158
|
170 180 190
....*....|....*....|....*....|
gi 639228517 489 DLQNIEILTNAIRDYK---GTLLVISHDDV 515
Cdd:PRK13540 159 DELSLLTIITKIQEHRakgGAVLLTSHQDL 188
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
361-512 |
1.53e-09 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 57.81 E-value: 1.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradfnsvyID-QDYSMIN-----HSLSVIQQAESfnwlpLPEHE 434
Cdd:cd03369 31 VKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIE--------IDgIDISTIPledlrSSLTIIPQDPT-----LFSGT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 435 VKTILSRF-------LFGKETWDKSCSVLSGGERMRLLLAcLSITgKAPDIIILDEPTNNLDLQNIEILTNAIRD--YKG 505
Cdd:cd03369 98 IRSNLDPFdeysdeeIYGALRVSEGGLNLSQGQRQLLCLA-RALL-KRPRVLVLDEATASIDYATDALIQKTIREefTNS 175
|
....*..
gi 639228517 506 TLLVISH 512
Cdd:cd03369 176 TILTIAH 182
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
360-489 |
1.70e-09 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 57.56 E-value: 1.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 360 VVSSGERILIIGENGSGKTTLIKLLLGQmkpsegTIERADFNSVYIDQdysmINHSLSVIQQAESFnwlpLPEHEvktIL 439
Cdd:cd03213 31 KAKPGELTAIMGPSGAGKSTLLNALAGR------RTGLGVSGEVLING----RPLDKRSFRKIIGY----VPQDD---IL 93
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 639228517 440 SRFLFGKETWDKS--CSVLSGGERMRLLLACLSITGkaPDIIILDEPTNNLD 489
Cdd:cd03213 94 HPTLTVRETLMFAakLRGLSGGERKRVSIALELVSN--PSLLFLDEPTSGLD 143
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
357-527 |
1.75e-09 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 57.89 E-value: 1.75e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI----------ERADFNSVYIDQDYSMINHsLSVIQQ----- 421
Cdd:cd03298 17 FDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVlingvdvtaaPPADRPVSMLFQENNLFAH-LTVEQNvglgl 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 422 AESFNWLPLPEHEVKTILSRF-LFGKETwdKSCSVLSGGERMRLLLACLSITGKApdIIILDEPTNNLD--LQN--IEIL 496
Cdd:cd03298 96 SPGLKLTAEDRQAIEVALARVgLAGLEK--RLPGELSGGERQRVALARVLVRDKP--VLLLDEPFAALDpaLRAemLDLV 171
|
170 180 190
....*....|....*....|....*....|.
gi 639228517 497 TNAIRDYKGTLLVISHDdvFSEEINIETRIL 527
Cdd:cd03298 172 LDLHAETKMTVLMVTHQ--PEDAKRLAQRVV 200
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
337-528 |
1.93e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 58.85 E-value: 1.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGT-----IERADFNS--------- 402
Cdd:PRK13644 1 MIRLENVSYSYPDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKvlvsgIDTGDFSKlqgirklvg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 403 -VYIDQDYSMINHSlsvIQQAESF--NWLPLPEHEVKTILSRFL--FGKETW-DKSCSVLSGGERMRLLLAclSITGKAP 476
Cdd:PRK13644 81 iVFQNPETQFVGRT---VEEDLAFgpENLCLPPIEIRKRVDRALaeIGLEKYrHRSPKTLSGGQGQCVALA--GILTMEP 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 477 DIIILDEPTNNLDLQNIEILTNAIRDY--KG-TLLVISHDdvfSEEINIETRILL 528
Cdd:PRK13644 156 ECLIFDEVTSMLDPDSGIAVLERIKKLheKGkTIVYITHN---LEELHDADRIIV 207
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
349-512 |
2.41e-09 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 57.15 E-value: 2.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 349 DKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQM--KPSEGTIeradfnsVYIDQDysmINHsLSVIQQAE--- 423
Cdd:cd03217 12 GKEILKG-VNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEI-------LFKGED---ITD-LPPEERARlgi 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 424 --SFNWlPLPEHEVKtiLSRFLfgketwdKSCSV-LSGGERMRLLLACLSITGkaPDIIILDEPTNNLDLQNIEILTNAI 500
Cdd:cd03217 80 flAFQY-PPEIPGVK--NADFL-------RYVNEgFSGGEKKRNEILQLLLLE--PDLAILDEPDSGLDIDALRLVAEVI 147
|
170
....*....|....*
gi 639228517 501 ---RDYKGTLLVISH 512
Cdd:cd03217 148 nklREEGKSVLIITH 162
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
338-513 |
2.46e-09 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 58.56 E-value: 2.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWK-KPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQDYSMIN 413
Cdd:PRK13651 3 IKVKNIVKIFNKKLPTElKALDNVsveINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKKKTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 414 HSLSVIQQAESFNWLP--------------LPEHEV--KTILSRFLFG-------------------------KETWDKS 452
Cdd:PRK13651 83 VLEKLVIQKTRFKKIKkikeirrrvgvvfqFAEYQLfeQTIEKDIIFGpvsmgvskeeakkraakyielvgldESYLQRS 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 453 CSVLSGGERMRLLLAclSITGKAPDIIILDEPTNNLDLQNI----EILTNAIRDYKgTLLVISHD 513
Cdd:PRK13651 163 PFELSGGQKRRVALA--GILAMEPDFLVFDEPTAGLDPQGVkeilEIFDNLNKQGK-TIILVTHD 224
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
2-194 |
2.46e-09 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 59.65 E-value: 2.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEIL-FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG---SVYYLPQILEQF-- 75
Cdd:PRK11176 342 IEFRNVTFTYPGKEVPaLRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGhdlRDYTLASLRNQVal 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 76 ---------DT--QSIARAlgVQKKLSalREILEGIVTEENITvlddnwDLEEKIKQALETwglldfTADESMNRLSGGQ 144
Cdd:PRK11176 422 vsqnvhlfnDTiaNNIAYA--RTEQYS--REQIEEAARMAYAM------DFINKMDNGLDT------VIGENGVLLSGGQ 485
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE--NTNKTLLVVSH 194
Cdd:PRK11176 486 RQRIAIARALLRDSPILILDEATSALDTESERAIQAALDelQKNRTSLVIAH 537
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
357-397 |
2.56e-09 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 57.78 E-value: 2.56e-09
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIER 397
Cdd:COG1134 45 VSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEV 85
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
338-526 |
2.76e-09 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 57.26 E-value: 2.76e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI----------ERADFNSVYIDQ 407
Cdd:cd03301 1 VELENVTKRFGNVTALDD-LNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIyiggrdvtdlPPKDRDIAMVFQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 408 DYSMINHsLSVIQQAEsfnwLPL-----PEHEVK---TILSRFLFGKETWDKSCSVLSGGERMRLLLAcLSITGKaPDII 479
Cdd:cd03301 80 NYALYPH-MTVYDNIA----FGLklrkvPKDEIDervREVAELLQIEHLLDRKPKQLSGGQRQRVALG-RAIVRE-PKVF 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 480 ILDEPTNNLD----LQNIEILTNAIRDYKGTLLVISHDDVfsEEINIETRI 526
Cdd:cd03301 153 LMDEPLSNLDaklrVQMRAELKRLQQRLGTTTIYVTHDQV--EAMTMADRI 201
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
32-194 |
2.82e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 57.93 E-value: 2.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 32 AIVGNNGSGKSTLLKLISGL--LTPSA---GDIRTEGSVYYLPQIleqfdtqsiaRALGVQKKLSALREI---LEGIVTE 103
Cdd:PRK14267 34 ALMGPSGCGKSTLLRTFNRLleLNEEArveGEVRLFGRNIYSPDV----------DPIEVRREVGMVFQYpnpFPHLTIY 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 104 ENITV-------LDDNWDLEEKIKQALETWGLLDFTAD---ESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLD-- 171
Cdd:PRK14267 104 DNVAIgvklnglVKSKKELDERVEWALKKAALWDEVKDrlnDYPSNLSGGQRQRLVIARALAMKPKILLMDEPTANIDpv 183
|
170 180
....*....|....*....|....*
gi 639228517 172 --RQSREQLYEFieNTNKTLLVVSH 194
Cdd:PRK14267 184 gtAKIEELLFEL--KKEYTIVLVTH 206
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
358-512 |
3.70e-09 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 58.88 E-value: 3.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 358 DVVVSSGErIL-IIGENGSGKTTLIKLLLGQMKPSEGTI----ERADFNS-----------VYidQDYSMInHSLSVIQ- 420
Cdd:COG3845 25 SLTVRPGE-IHaLLGENGAGKSTLMKILYGLYQPDSGEIlidgKPVRIRSprdaialgigmVH--QHFMLV-PNLTVAEn 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 421 ---QAESFNWLPLP----EHEVKTILSRFLF----GKETWDkscsvLSGGERMRL-LLACLsITGkaPDIIILDEPTNNL 488
Cdd:COG3845 101 ivlGLEPTKGGRLDrkaaRARIRELSERYGLdvdpDAKVED-----LSVGEQQRVeILKAL-YRG--ARILILDEPTAVL 172
|
170 180
....*....|....*....|....*..
gi 639228517 489 DLQNIEILTNAIRDYKG---TLLVISH 512
Cdd:COG3845 173 TPQEADELFEILRRLAAegkSIIFITH 199
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
332-397 |
3.76e-09 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 57.16 E-value: 3.76e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 332 HRGKILIKAEHINhAYQDKNIWKKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIER 397
Cdd:cd03220 14 KGGSSSLKKLGIL-GRKGEVGEFWALKDVsfeVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTV 81
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
302-512 |
3.99e-09 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 58.96 E-value: 3.99e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 302 IEGLSQE--LQQL----RRGVPLTD--QMKLGFDQANLHRGKILIkaEHINHAYQDKNIWKKPLDVVVSSGERILIIGEN 373
Cdd:PRK10790 299 IELTTQQsmLQQAvvagERVFELMDgpRQQYGNDDRPLQSGRIDI--DNVSFAYRDDNLVLQNINLSVPSRGFVALVGHT 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 374 GSGKTTLIKLLLGQMKPSEGTIeradfnsvYID-QDYSMINHS-----LSVIQQ-----AESF--N------------WL 428
Cdd:PRK10790 377 GSGKSTLASLLMGYYPLTEGEI--------RLDgRPLSSLSHSvlrqgVAMVQQdpvvlADTFlaNvtlgrdiseeqvWQ 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 429 PLPEHEVKTILSRFLFGKET-WDKSCSVLSGGERMrlLLACLSITGKAPDIIILDEPTNNLDL---QNIEILTNAIRDyK 504
Cdd:PRK10790 449 ALETVQLAELARSLPDGLYTpLGEQGNNLSVGQKQ--LLALARVLVQTPQILILDEATANIDSgteQAIQQALAAVRE-H 525
|
....*...
gi 639228517 505 GTLLVISH 512
Cdd:PRK10790 526 TTLVVIAH 533
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
338-520 |
4.25e-09 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 56.77 E-value: 4.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradFNSVYIDQDYSMINhslS 417
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKG-IDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTII---IDGLKLTDDKKNIN---E 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 418 VIQQA----ESFNWLP-----------------LPEHEVKTILSRFL--FG-KETWDKSCSVLSGGERMRLLLAclsitg 473
Cdd:cd03262 74 LRQKVgmvfQQFNLFPhltvlenitlapikvkgMSKAEAEERALELLekVGlADKADAYPAQLSGGQQQRVAIA------ 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 474 KA----PDIIILDEPTNNLDLQNI-EILtNAIRD--YKG-TLLVISHDDVFSEEI 520
Cdd:cd03262 148 RAlamnPKVMLFDEPTSALDPELVgEVL-DVMKDlaEEGmTMVVVTHEMGFAREV 201
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
20-283 |
4.51e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 59.22 E-value: 4.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTP---SAGDIRteGSVYYLPQILEQFDtqsiaralgvqkklSALRE- 95
Cdd:PLN03232 635 DINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHaetSSVVIR--GSVAYVPQVSWIFN--------------ATVREn 698
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 96 ILEGIVTEE-------NITVLDDNWDLeekikqaletWGLLDFT--ADESMNrLSGGQKTKVLIAGIEIHQPDIILMDEP 166
Cdd:PLN03232 699 ILFGSDFESerywraiDVTALQHDLDL----------LPGRDLTeiGERGVN-ISGGQKQRVSMARAVYSNSDIYIFDDP 767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 167 TNHLDRQSREQLYEFI---ENTNKTLLVVSHDRTLLNLLPKTAELSrKEMMLYGGNYDSYKEQKQIQQNALQNSIK---- 239
Cdd:PLN03232 768 LSALDAHVAHQVFDSCmkdELKGKTRVLVTNQLHFLPLMDRIILVS-EGMIKEEGTFAELSKSGSLFKKLMENAGKmdat 846
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 240 -----NTENALKKAKATERETLERQQKLDAKGKK------KQEKAGVAKIMMNTL 283
Cdd:PLN03232 847 qevntNDENILKLGPTVTIDVSERNLGSTKQGKRgrsvlvKQEERETGIISWNVL 901
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
338-513 |
5.02e-09 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 56.61 E-value: 5.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDkNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSV-----------YID 406
Cdd:cd03265 1 IEVENLVKKYGD-FEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVreprevrrrigIVF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 407 QDYSmINHSLSVIQQAESFNWL-PLPEHEVKTILSRFLFGKETW---DKSCSVLSGGERMRLLLACLSITGkaPDIIILD 482
Cdd:cd03265 80 QDLS-VDDELTGWENLYIHARLyGVPGAERRERIDELLDFVGLLeaaDRLVKTYSGGMRRRLEIARSLVHR--PEVLFLD 156
|
170 180 190
....*....|....*....|....*....|....*
gi 639228517 483 EPTNNLDLQNIEILTNAIRDYKG----TLLVISHD 513
Cdd:cd03265 157 EPTIGLDPQTRAHVWEYIEKLKEefgmTILLTTHY 191
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
356-513 |
5.66e-09 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 56.86 E-value: 5.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 356 PLDVVVSSGERILIIGENGSGKTTLIKLLLGqMKPSEGTIERADFNSvyidQDYSMinHSLSVI-----QQAES------ 424
Cdd:PRK03695 14 PLSAEVRAGEILHLVGPNGAGKSTLLARMAG-LLPGSGSIQFAGQPL----EAWSA--AELARHraylsQQQTPpfampv 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 425 FNWLPL----------PEHEVKTILSRFLFGketwDK---SCSVLSGGE--RMRLLLACLSITgkaPDI------IILDE 483
Cdd:PRK03695 87 FQYLTLhqpdktrteaVASALNEVAEALGLD----DKlgrSVNQLSGGEwqRVRLAAVVLQVW---PDInpagqlLLLDE 159
|
170 180 190
....*....|....*....|....*....|...
gi 639228517 484 PTNNLDLQNIEILTNAIRDY---KGTLLVISHD 513
Cdd:PRK03695 160 PMNSLDVAQQAALDRLLSELcqqGIAVVMSSHD 192
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
22-514 |
5.87e-09 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 58.49 E-value: 5.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 22 NFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTegsvyylpqileQFdtQSIARalgvqkkLSAlrEILEGIV 101
Cdd:PRK10938 23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQS------------QF--SHITR-------LSF--EQLQKLV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 102 TEEnitVLDDNWDL-----EEKIKQALETwgLLDFTADES--------------MNR----LSGGQKTKVLIAGIEIHQP 158
Cdd:PRK10938 80 SDE---WQRNNTDMlspgeDDTGRTTAEI--IQDEVKDPArceqlaqqfgitalLDRrfkyLSTGETRKTLLCQALMSEP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 159 DIILMDEPTNHLDRQSREQLYEFIENTNK---TL-LVVSHDRTLLNLLPKTAELSRKEMMLYGgnydsykeqkqiqqnal 234
Cdd:PRK10938 155 DLLILDEPFDGLDVASRQQLAELLASLHQsgiTLvLVLNRFDEIPDFVQFAGVLADCTLAETG----------------- 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 235 qnsikntenalkkakatERETLERQqkldakgkkkqekAGVAKImmntlrnnaenstakirdTHSDKIEGLSqelqqlrr 314
Cdd:PRK10938 218 -----------------EREEILQQ-------------ALVAQL------------------AHSEQLEGVQ-------- 241
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 315 gVPLTD----QMKLGFDQAnlhrgkiLIKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKL------- 383
Cdd:PRK10938 242 -LPEPDepsaRHALPANEP-------RIVLNNGVVSYNDRPILHN-LSWQVNPGEHWQIVGPNGAGKSTLLSLitgdhpq 312
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 384 -------LLGQMKPSEGTI----ERADFNSVYIDQDYSMINHSLSVI-----------------QQAESFNWlplpehev 435
Cdd:PRK10938 313 gysndltLFGRRRGSGETIwdikKHIGYVSSSLHLDYRVSTSVRNVIlsgffdsigiyqavsdrQQKLAQQW-------- 384
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 436 ktiLSRFLFGKETWDKSCSVLSGGERmRLLLACLSITgKAPDIIILDEPTNNLDLQN-------IEILtnaIRDYKGTLL 508
Cdd:PRK10938 385 ---LDILGIDKRTADAPFHSLSWGQQ-RLALIVRALV-KHPTLLILDEPLQGLDPLNrqlvrrfVDVL---ISEGETQLL 456
|
....*.
gi 639228517 509 VISHDD 514
Cdd:PRK10938 457 FVSHHA 462
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
325-514 |
6.47e-09 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 58.44 E-value: 6.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 325 GFDQANLHRGKILIKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI--------- 395
Cdd:PRK10522 310 EFPRPQAFPDWQTLELRNVTFAYQDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEIlldgkpvta 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 396 -----ERADFNSVYidQDYSMINHSL-SVIQQAES---FNWLPLPEHEVKTILS--RFLFGKetwdkscsvLSGGERMR- 463
Cdd:PRK10522 390 eqpedYRKLFSAVF--TDFHLFDQLLgPEGKPANPalvEKWLERLKMAHKLELEdgRISNLK---------LSKGQKKRl 458
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 464 -LLLACLsitgKAPDIIILDEPTNNLDLQNIEI----LTNAIRDYKGTLLVISHDD 514
Cdd:PRK10522 459 aLLLALA----EERDILLLDEWAADQDPHFRREfyqvLLPLLQEMGKTIFAISHDD 510
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
21-205 |
7.16e-09 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 58.80 E-value: 7.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 21 LNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQileQFDTQSiaralgvqkklSALRE-ILEG 99
Cdd:TIGR00957 657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGSVAYVPQ---QAWIQN-----------DSLREnILFG 722
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 100 IVTEENitvlddnwdleeKIKQALETWGLL-DFTADESMNR---------LSGGQKTKVLIAGIEIHQPDIILMDEPTNH 169
Cdd:TIGR00957 723 KALNEK------------YYQQVLEACALLpDLEILPSGDRteigekgvnLSGGQKQRVSLARAVYSNADIYLFDDPLSA 790
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 639228517 170 LDRQSREQLYEFIEN-----TNKTLLVVSHDrtlLNLLPKT 205
Cdd:TIGR00957 791 VDAHVGKHIFEHVIGpegvlKNKTRILVTHG---ISYLPQV 828
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
369-522 |
7.74e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 57.10 E-value: 7.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 369 IIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQDYSM--INHSLSVIQQ------------------AESFNwl 428
Cdd:PRK13646 38 IVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIrpVRKRIGMVFQfpesqlfedtvereiifgPKNFK-- 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 429 pLPEHEVKT----ILSRFLFGKETWDKSCSVLSGGErMRLLlACLSITGKAPDIIILDEPTNNLD----LQNIEILTNAI 500
Cdd:PRK13646 116 -MNLDEVKNyahrLLMDLGFSRDVMSQSPFQMSGGQ-MRKI-AIVSILAMNPDIIVLDEPTAGLDpqskRQVMRLLKSLQ 192
|
170 180
....*....|....*....|....*.
gi 639228517 501 RDYKGTLLVISHD--DV--FSEEINI 522
Cdd:PRK13646 193 TDENKTIILVSHDmnEVarYADEVIV 218
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
23-213 |
7.92e-09 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 57.28 E-value: 7.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 23 FIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPsagdirTEGSVYYLPQILEQFDTQSIAR--------------ALGVQK 88
Cdd:PRK11308 36 FTLERGKTLAVVGESGCGKSTLARLLTMIETP------TGGELYYQGQDLLKADPEAQKLlrqkiqivfqnpygSLNPRK 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 89 KLSAlreILEgivteeniTVLDDNWDL-----EEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIHQPDIILM 163
Cdd:PRK11308 110 KVGQ---ILE--------EPLLINTSLsaaerREKALAMMAKVGLRPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVA 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 164 DEPTNHLDRQSREQL--------------YEFIENtnkTLLVVSH--DRTLLNLLPKTAELSRKEM 213
Cdd:PRK11308 179 DEPVSALDVSVQAQVlnlmmdlqqelglsYVFISH---DLSVVEHiaDEVMVMYLGRCVEKGTKEQ 241
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
331-508 |
8.21e-09 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 56.01 E-value: 8.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 331 LHRGKILIKAEHINHAYQDKNIWKkPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI----------ERADF 400
Cdd:PRK13543 5 LHTAPPLLAAHALAFSRNEEPVFG-PLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIqidgktatrgDRSRF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 401 NSvYIDQdYSMINHSLSVIQQAESFNWL------PLPEHEVkTILSrfLFGKEtwDKSCSVLSGGERMRLLLACLSITgK 474
Cdd:PRK13543 84 MA-YLGH-LPGLKADLSTLENLHFLCGLhgrrakQMPGSAL-AIVG--LAGYE--DTLVRQLSAGQKKRLALARLWLS-P 155
|
170 180 190
....*....|....*....|....*....|....*...
gi 639228517 475 APdIIILDEPTNNLDLQNI----EILTNAIRDYKGTLL 508
Cdd:PRK13543 156 AP-LWLLDEPYANLDLEGItlvnRMISAHLRGGGAALV 192
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
25-182 |
8.22e-09 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 58.49 E-value: 8.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 25 VNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpQILEqfDTQSIARALGVQKKLSALREILEGivtEE 104
Cdd:TIGR01257 1962 VRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGK-----SILT--NISDVHQNMGYCPQFDAIDDLLTG---RE 2031
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 105 NITVLDDNWDLEEKIKQALETWGL----LDFTADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYE 180
Cdd:TIGR01257 2032 HLYLYARLRGVPAEEIEKVANWSIqslgLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWN 2111
|
..
gi 639228517 181 FI 182
Cdd:TIGR01257 2112 TI 2113
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
338-515 |
8.64e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 56.76 E-value: 8.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQ-DKNIWKKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFnsvYIDQDYSmiN 413
Cdd:PRK13641 3 IKFENVDYIYSpGTPMEKKGLDNIsfeLEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGY---HITPETG--N 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 414 HSLSVIQQAESFNWlPLPEHEV--KTILSRFLFG-------------------------KETWDKSCSVLSGGERMRLLL 466
Cdd:PRK13641 78 KNLKKLRKKVSLVF-QFPEAQLfeNTVLKDVEFGpknfgfsedeakekalkwlkkvglsEDLISKSPFELSGGQMRRVAI 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 639228517 467 AclSITGKAPDIIILDEPTNNLDLQNIEILTNAIRDYKG---TLLVISH--DDV 515
Cdd:PRK13641 157 A--GVMAYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQKaghTVILVTHnmDDV 208
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
20-219 |
8.80e-09 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 55.73 E-value: 8.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLtpsAGDIRTEGSVYY----LPQILEQFDTQSIaralgvqkklsalre 95
Cdd:cd03233 25 DFSGVVKPGEMVLVLGRPGSGCSTLLKALANRT---EGNVSVEGDIHYngipYKEFAEKYPGEII--------------- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 96 ilegIVTEE-----NITVlddnwdlEEKIKQALETWGlldftaDESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHL 170
Cdd:cd03233 87 ----YVSEEdvhfpTLTV-------RETLDFALRCKG------NEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGL 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 639228517 171 DRQSREQLYEFIEN----TNKTLLVvshdrTLLNLLPKTAELSRKEMMLYGGN 219
Cdd:cd03233 150 DSSTALEILKCIRTmadvLKTTTFV-----SLYQASDEIYDLFDKVLVLYEGR 197
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
338-526 |
9.39e-09 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 56.09 E-value: 9.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKkPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERAD------------FNSVYi 405
Cdd:cd03300 1 IELENVSKFYGGFVALD-GVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGkditnlpphkrpVNTVF- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 406 dQDYSMINHsLSVIQQ-AESFNWLPLPEHEVKTILSRFLFG---KETWDKSCSVLSGGERMRLLLAclsitgKA----PD 477
Cdd:cd03300 79 -QNYALFPH-LTVFENiAFGLRLKKLPKAEIKERVAEALDLvqlEGYANRKPSQLSGGQQQRVAIA------RAlvnePK 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 639228517 478 IIILDEPTNNLDL---QNIEILTNAIRDYKG-TLLVISHDDvfSEEINIETRI 526
Cdd:cd03300 151 VLLLDEPLGALDLklrKDMQLELKRLQKELGiTFVFVTHDQ--EEALTMSDRI 201
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
363-526 |
9.74e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 54.30 E-value: 9.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 363 SGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeradfnsVYIDqdysminhslsviqqAESFNWLPLPEHEVKTILSRF 442
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGV-------IYID---------------GEDILEEVLDQLLLIIVGGKK 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 443 LFGketwdkscsvlSGGERMRLLLACLSitGKAPDIIILDEPTNNLD---------LQNIEILTNAIRDYKGTLLVISHD 513
Cdd:smart00382 59 ASG-----------SGELRLRLALALAR--KLKPDVLILDEITSLLDaeqeallllLEELRLLLLLKSEKNLTVILTTND 125
|
170
....*....|...
gi 639228517 514 DVFSEEINIETRI 526
Cdd:smart00382 126 EKDLGPALLRRRF 138
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
357-519 |
9.80e-09 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 55.02 E-value: 9.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLL---GQMKPSEGTIERADFNSVYIDQDYSMINHSLsviqqaesfNWLPLpeh 433
Cdd:cd03238 14 LDVSIPLNVLVVVTGVSGSGKSTLVNEGLyasGKARLISFLPKFSRNKLIFIDQLQFLIDVGL---------GYLTL--- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 434 evktilsrflfgketwDKSCSVLSGGERMRLLLACLSITGKAPDIIILDEPTNNLDLQNIEILTNAIR---DYKGTLLVI 510
Cdd:cd03238 82 ----------------GQKLSTLSGGELQRVKLASELFSEPPGTLFILDEPSTGLHQQDINQLLEVIKgliDLGNTVILI 145
|
....*....
gi 639228517 511 SHDDVFSEE 519
Cdd:cd03238 146 EHNLDVLSS 154
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-183 |
1.04e-08 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 56.04 E-value: 1.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITyQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGllTPSAgdirTEGSVYYLPQILEQFDTQSI 80
Cdd:PRK11614 5 MLSFDKVS-AHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCG--DPRA----TSGRIVFDGKDITDWQTAKI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 AR-ALGVqkkLSALREILEGIVTEENITV---LDDNWDLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIH 156
Cdd:PRK11614 78 MReAVAI---VPEGRRVFSRMTVEENLAMggfFAERDQFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMS 154
|
170 180
....*....|....*....|....*..
gi 639228517 157 QPDIILMDEPTNHLDRQSREQLYEFIE 183
Cdd:PRK11614 155 QPRLLLLDEPSLGLAPIIIQQIFDTIE 181
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
335-513 |
1.22e-08 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 55.59 E-value: 1.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 335 KILIKAEHINHAYQDKNIWKKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI--ERADFNSVYIDQDY 409
Cdd:PRK11629 3 KILLQCDNLCKRYQEGSVQTDVLHNVsfsIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVifNGQPMSKLSSAAKA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 410 SMINHSLSVIQQaesFNWLpLPE-HEVKTILSRFLFGK----ETWDKSC----------------SVLSGGERMRLLLAC 468
Cdd:PRK11629 83 ELRNQKLGFIYQ---FHHL-LPDfTALENVAMPLLIGKkkpaEINSRALemlaavglehranhrpSELSGGERQRVAIAR 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 639228517 469 LSITgkAPDIIILDEPTNNLDLQN---IEILTNAIRDYKGT-LLVISHD 513
Cdd:PRK11629 159 ALVN--NPRLVLADEPTGNLDARNadsIFQLLGELNRLQGTaFLVVTHD 205
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
18-195 |
1.32e-08 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 56.09 E-value: 1.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 18 FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAgdirteGSVYYLPQILEQFDTQSIARA---------LGV-- 86
Cdd:PRK11701 22 CRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDA------GEVHYRMRDGQLRDLYALSEAerrrllrteWGFvh 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 87 QKKLSALREILE--GIVTEENITVLDDNWdleEKIKQALETWgLLDFTADESmnRL-------SGGQKTKVLIAGIEIHQ 157
Cdd:PRK11701 96 QHPRDGLRMQVSagGNIGERLMAVGARHY---GDIRATAGDW-LERVEIDAA--RIddlpttfSGGMQQRLQIARNLVTH 169
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 639228517 158 PDIILMDEPTNHLD--RQSR--EQLYEFIENTNKTLLVVSHD 195
Cdd:PRK11701 170 PRLVFMDEPTGGLDvsVQARllDLLRGLVRELGLAVVIVTHD 211
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
369-512 |
1.47e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 56.40 E-value: 1.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 369 IIGENGSGKTTLIKLLLGQMKPSEGTIERADFnsvYIDQDYSMINHSLSVIQQA-ESFNWL--------PLPEHEV--KT 437
Cdd:PRK13631 57 IIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDI---YIGDKKNNHELITNPYSKKiKNFKELrrrvsmvfQFPEYQLfkDT 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 438 ILSRFLFG------------------------KETW-DKSCSVLSGGERMRLLLAclSITGKAPDIIILDEPTNNLDLQN 492
Cdd:PRK13631 134 IEKDIMFGpvalgvkkseakklakfylnkmglDDSYlERSPFGLSGGQKRRVAIA--GILAIQPEILIFDEPTAGLDPKG 211
|
170 180
....*....|....*....|...
gi 639228517 493 IEILTNAIRDYKG---TLLVISH 512
Cdd:PRK13631 212 EHEMMQLILDAKAnnkTVFVITH 234
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
361-510 |
1.48e-08 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 55.35 E-value: 1.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGqMKPSEGTI-----------ERADF--NSVYIDQDYSMINHsLSVIQQAESFNW 427
Cdd:cd03234 30 VESGQVMAILGSSGSGKTTLLDAISG-RVEGGGTTsgqilfngqprKPDQFqkCVAYVRQDDILLPG-LTVRETLTYTAI 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 428 LPLPEH--------EVKTILSRFLFGKETWDKSCSVLSGGERMRLLLACLSITgkAPDIIILDEPTNNLD----LQNIEI 495
Cdd:cd03234 108 LRLPRKssdairkkRVEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLW--DPKVLILDEPTSGLDsftaLNLVST 185
|
170
....*....|....*
gi 639228517 496 LTNAIRDYKGTLLVI 510
Cdd:cd03234 186 LSQLARRNRIVILTI 200
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
20-229 |
1.72e-08 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 57.21 E-value: 1.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYlpqileqfdtqsIARALGVQKKLSALREI-LE 98
Cdd:PRK13545 42 NISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAAL------------IAISSGLNGQLTGIENIeLK 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 99 GI---VTEENItvlddnwdlEEKIKQALETWGLLDFTaDESMNRLSGGQKTKVLIAgIEIH-QPDIILMDEPTNHLD--- 171
Cdd:PRK13545 110 GLmmgLTKEKI---------KEIIPEIIEFADIGKFI-YQPVKTYSSGMKSRLGFA-ISVHiNPDILVIDEALSVGDqtf 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 172 -RQSREQLYEFIENtNKTLLVVSHDrtllnlLPKTAELSRKEMMLYGGNYDSYKEQKQI 229
Cdd:PRK13545 179 tKKCLDKMNEFKEQ-GKTIFFISHS------LSQVKSFCTKALWLHYGQVKEYGDIKEV 230
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
19-513 |
1.77e-08 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 57.00 E-value: 1.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKS-TLLKLIsGLLTPSAgdIRTEGSVyylpqileQFDTQSIARAlgVQKKLSALR--E 95
Cdd:COG4172 27 KGVSFDIAAGETLALVGESGSGKSvTALSIL-RLLPDPA--AHPSGSI--------LFDGQDLLGL--SERELRRIRgnR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 96 IleGIVTEENITVLDDNWDLEEKI----------------KQALEtwgLLDFT----ADESMNR----LSGGQKTKVLIA 151
Cdd:COG4172 94 I--AMIFQEPMTSLNPLHTIGKQIaevlrlhrglsgaaarARALE---LLERVgipdPERRLDAyphqLSGGQRQRVMIA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 152 GIEIHQPDIILMDEPTNHLD----RQSREQLYEFIENTNKTLLVVSHDrtlLNLLPKTAElsRKEMMlyggnydsykeqk 227
Cdd:COG4172 169 MALANEPDLLIADEPTTALDvtvqAQILDLLKDLQRELGMALLLITHD---LGVVRRFAD--RVAVM------------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 228 qiqqnalqnsikntenalKKAKATERETLER----------QQKLDA--KGKKKQEKAGvAKIMMntlrnnaenstakir 295
Cdd:COG4172 231 ------------------RQGEIVEQGPTAElfaapqhpytRKLLAAepRGDPRPVPPD-APPLL--------------- 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 296 dthsdkieglsqELQQLRRGVPLtdqmklgfdqanlhRGKILIKAEHINHAYQDkniwkkpLDVVVSSGERILIIGENGS 375
Cdd:COG4172 277 ------------EARDLKVWFPI--------------KRGLFRRTVGHVKAVDG-------VSLTLRRGETLGLVGESGS 323
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 376 GKTTLIKLLLGqMKPSEGTIE-----------------RADFNSVYidQD-YSMINHSLSVIQQ-AEsfnwlPLPEHEVK 436
Cdd:COG4172 324 GKSTLGLALLR-LIPSEGEIRfdgqdldglsrralrplRRRMQVVF--QDpFGSLSPRMTVGQIiAE-----GLRVHGPG 395
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 437 tiLSRflfgKETWDKSCSVL-----------------SGGERMRLLLAclsitgKA----PDIIILDEPTNNLDL----Q 491
Cdd:COG4172 396 --LSA----AERRARVAEALeevgldpaarhryphefSGGQRQRIAIA------RAlilePKLLVLDEPTSALDVsvqaQ 463
|
570 580
....*....|....*....|..
gi 639228517 492 NIEILTNAIRDYKGTLLVISHD 513
Cdd:COG4172 464 ILDLLRDLQREHGLAYLFISHD 485
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
2-298 |
2.52e-08 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 56.84 E-value: 2.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQH-PDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTpSAGDIRTEGSVYylpqilEQFDTQSI 80
Cdd:TIGR01271 1218 MDVQGLTAKYtEAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGVSW------NSVTLQTW 1290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGV--QKKLsalreILEGIVTEEnitvLD--DNWDLEEKIKQALETwGL----------LDFTADESMNRLSGGQKT 146
Cdd:TIGR01271 1291 RKAFGVipQKVF-----IFSGTFRKN----LDpyEQWSDEEIWKVAEEV-GLksvieqfpdkLDFVLVDGGYVLSNGHKQ 1360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 147 KVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENT--NKTLLVVSHdrtllnllpktaelsRKEMMLYGGNYDSYK 224
Cdd:TIGR01271 1361 LMCLARSILSKAKILLLDEPSAHLDPVTLQIIRKTLKQSfsNCTVILSEH---------------RVEALLECQQFLVIE 1425
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639228517 225 EQKQIQQNALQNSIKNTENALKKAKATERETLERQQKLDAKGKKKQEKagvakimMNTLRNNAENstaKIRDTH 298
Cdd:TIGR01271 1426 GSSVKQYDSIQKLLNETSLFKQAMSAADRLKLFPLHRRNSSKRKPQPK-------ITALREEAEE---EVQNTR 1489
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
6-229 |
3.25e-08 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 55.50 E-value: 3.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 6 NITYQHPDKEILFEN-LNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLtpsAGDIRTEGSVyylpqileQFDTQSIaraL 84
Cdd:PRK09473 19 RVTFSTPDGDVTAVNdLNFSLRAGETLGIVGESGSGKSQTAFALMGLL---AANGRIGGSA--------TFNGREI---L 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 85 GV-QKKLSALREILEGIVTEENITVLDDNWDLEEKIKQAL-------------ETWGLLDFT----ADESMN----RLSG 142
Cdd:PRK09473 85 NLpEKELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLmlhkgmskaeafeESVRMLDAVkmpeARKRMKmyphEFSG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 143 GQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQ----LYEFIENTNKTLLVVSHDrtllnlLPKTAELSRKEMMLYGG 218
Cdd:PRK09473 165 GMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQimtlLNELKREFNTAIIMITHD------LGVVAGICDKVLVMYAG 238
|
250
....*....|.
gi 639228517 219 NYDSYKEQKQI 229
Cdd:PRK09473 239 RTMEYGNARDV 249
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
18-193 |
3.30e-08 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 56.18 E-value: 3.30e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 18 FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqilEQFDTQSIARAL--GVqkklsAL-- 93
Cdd:COG1129 268 VRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDG---------KPVRIRSPRDAIraGI-----AYvp 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 94 ---REilEGIVTE----ENIT--VLDdnwdleekikqALETWGLLDF-----TADESMNR--------------LSGGQK 145
Cdd:COG1129 334 edrKG--EGLVLDlsirENITlaSLD-----------RLSRGGLLDRrreraLAEEYIKRlriktpspeqpvgnLSGGNQ 400
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 146 TKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVS 193
Cdd:COG1129 401 QKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRelaAEGKAVIVIS 451
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
19-202 |
3.35e-08 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 56.56 E-value: 3.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSvyylpqileqfdtqsiaralGVQKKLSALREILe 98
Cdd:TIGR01257 947 DRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGK--------------------DIETNLDAVRQSL- 1005
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 99 GIVTEENI-----TVLDD----------NWDLEE-KIKQALETWGlLDFTADESMNRLSGGQKTKVLIAGIEIHQPDIIL 162
Cdd:TIGR01257 1006 GMCPQHNIlfhhlTVAEHilfyaqlkgrSWEEAQlEMEAMLEDTG-LHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVV 1084
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 639228517 163 MDEPTNHLDRQSREQLYEFI--ENTNKTLLVVSHDRTLLNLL 202
Cdd:TIGR01257 1085 LDEPTSGVDPYSRRSIWDLLlkYRSGRTIIMSTHHMDEADLL 1126
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
355-512 |
3.40e-08 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 54.04 E-value: 3.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 355 KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeradfnsvYID-QDYSMINH-----SLSVIQQaESF--- 425
Cdd:cd03244 21 KNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSI--------LIDgVDISKIGLhdlrsRISIIPQ-DPVlfs 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 426 -----NWLPLPEHE------------VKTILSRFLFGKETWDKSC-SVLSGGERMRLLLA--CLsitgKAPDIIILDEPT 485
Cdd:cd03244 92 gtirsNLDPFGEYSdeelwqalervgLKEFVESLPGGLDTVVEEGgENLSVGQRQLLCLAraLL----RKSKILVLDEAT 167
|
170 180
....*....|....*....|....*....
gi 639228517 486 NNLDLQNIEILTNAIRDY-KG-TLLVISH 512
Cdd:cd03244 168 ASVDPETDALIQKTIREAfKDcTVLTIAH 196
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
337-515 |
3.48e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 54.70 E-value: 3.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIErADFNSVYIDQDySMINHSL 416
Cdd:PRK13639 1 ILETRDLKYSYPDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVL-IKGEPIKYDKK-SLLEVRK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 417 SV---------------IQQAESFNW--LPLPEHEVKTILSRFL--FGKETWD-KSCSVLSGGERMRLLLAclSITGKAP 476
Cdd:PRK13639 79 TVgivfqnpddqlfaptVEEDVAFGPlnLGLSKEEVEKRVKEALkaVGMEGFEnKPPHHLSGGQKKRVAIA--GILAMKP 156
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 639228517 477 DIIILDEPTNNLDLQNIEILTNAIRDY--KGTLLVISHDDV 515
Cdd:PRK13639 157 EIIVLDEPTSGLDPMGASQIMKLLYDLnkEGITIIISTHDV 197
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
363-513 |
3.58e-08 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 53.84 E-value: 3.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 363 SGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeraDFNSV-------------------YIDQDYSMINHsLSVIQQAE 423
Cdd:cd03297 22 NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTI---VLNGTvlfdsrkkinlppqqrkigLVFQQYALFPH-LNVRENLA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 424 sfnwLPLPEHEVKTILSRF-----LFG-KETWDKSCSVLSGGERMRLLLACLSITgkAPDIIILDEPTNNLD----LQNI 493
Cdd:cd03297 98 ----FGLKRKRNREDRISVdelldLLGlDHLLNRYPAQLSGGEKQRVALARALAA--QPELLLLDEPFSALDralrLQLL 171
|
170 180
....*....|....*....|
gi 639228517 494 EILTNAIRDYKGTLLVISHD 513
Cdd:cd03297 172 PELKQIKKNLNIPVIFVTHD 191
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
25-195 |
3.60e-08 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 55.81 E-value: 3.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 25 VNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqFDTQSIARALGVQKKLSALREILEGIVTEE 104
Cdd:PRK10070 51 IEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDG-----------VDIAKISDAELREVRRKKIAMVFQSFALMP 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 105 NITVLDDNW-----------DLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLD-- 171
Cdd:PRK10070 120 HMTVLDNTAfgmelaginaeERREKALDALRQVGLENY-AHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDpl 198
|
170 180
....*....|....*....|....*.
gi 639228517 172 --RQSREQLYEFIENTNKTLLVVSHD 195
Cdd:PRK10070 199 irTEMQDELVKLQAKHQRTIVFISHD 224
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
338-489 |
3.74e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 55.03 E-value: 3.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKK----PLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADfnsvyidqdySMI- 412
Cdd:PRK13634 3 ITFQKVEHRYQYKTPFERralyDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGE----------RVIt 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 413 ----NHSLSVIQQAES--FNWlplPEHEV--KTILSRFLFG-------------------------KETWDKSCSVLSGG 459
Cdd:PRK13634 73 agkkNKKLKPLRKKVGivFQF---PEHQLfeETVEKDICFGpmnfgvseedakqkaremielvglpEELLARSPFELSGG 149
|
170 180 190
....*....|....*....|....*....|
gi 639228517 460 ERMRLLLAclSITGKAPDIIILDEPTNNLD 489
Cdd:PRK13634 150 QMRRVAIA--GVLAMEPEVLVLDEPTAGLD 177
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
25-202 |
3.91e-08 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 53.34 E-value: 3.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 25 VNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG-SVYYLPQileqfdtqsiaralgvqkklsalreilegivte 103
Cdd:cd03222 22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGiTPVYKPQ--------------------------------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 104 enitvlddnwdleeKIKqaletwglldftadesmnrLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSR----EQLY 179
Cdd:cd03222 69 --------------YID-------------------LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRlnaaRAIR 115
|
170 180
....*....|....*....|...
gi 639228517 180 EFIENTNKTLLVVSHDRTLLNLL 202
Cdd:cd03222 116 RLSEEGKKTALVVEHDLAVLDYL 138
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
19-265 |
4.52e-08 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 54.44 E-value: 4.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVyylpqileqfdtQSIARALGVQKKLSALREI-- 96
Cdd:PRK13546 41 DDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEV------------SVIAISAGLSGQLTGIENIef 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 97 ---LEGIVTEEnitvlddnwdLEEKIKQALETWGLLDFTAdESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDR- 172
Cdd:PRK13546 109 kmlCMGFKRKE----------IKAMTPKIIEFSELGEFIY-QPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQt 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 173 ---QSREQLYEFIEnTNKTLLVVSHDrtllnlLPKTAELSRKEMMLYGGNYDSYKEQKQI--QQNALQNSIKntenalKK 247
Cdd:PRK13546 178 faqKCLDKIYEFKE-QNKTIFFVSHN------LGQVRQFCTKIAWIEGGKLKDYGELDDVlpKYEAFLNDFK------KK 244
|
250
....*....|....*...
gi 639228517 248 AKATERETlerQQKLDAK 265
Cdd:PRK13546 245 SKAEQKEF---RNKLDES 259
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
357-513 |
4.56e-08 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 55.23 E-value: 4.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeRADFNSVYIDQDYSMINHSLSVIQQAE-SFNWlplpehEV 435
Cdd:PRK09536 22 VDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTV-LVAGDDVEALSARAASRRVASVPQDTSlSFEF------DV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 436 KTI--------LSRFLFGKET-----------------WDKSCSVLSGGERMRLLLAcLSITGKAPdIIILDEPTNNLDL 490
Cdd:PRK09536 95 RQVvemgrtphRSRFDTWTETdraaveramertgvaqfADRPVTSLSGGERQRVLLA-RALAQATP-VLLLDEPTASLDI 172
|
170 180
....*....|....*....|....*..
gi 639228517 491 ----QNIEILTNAIRDYKGTLLVIsHD 513
Cdd:PRK09536 173 nhqvRTLELVRRLVDDGKTAVAAI-HD 198
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
359-522 |
5.13e-08 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 53.91 E-value: 5.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 359 VVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYID-------QDY--SMINHSLSVIQQAESFNWLP 429
Cdd:cd03236 21 PVPREGQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDDPPDWDEILDefrgselQNYftKLLEGDVKVIVKPQYVDLIP 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 430 -------------LPEHEVKTILSRFLFGKETWDKSCSVLSGGERMRLLLAcLSITGKApDIIILDEPTNNLDLQ---NI 493
Cdd:cd03236 101 kavkgkvgellkkKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIA-AALARDA-DFYFFDEPSSYLDIKqrlNA 178
|
170 180 190
....*....|....*....|....*....|...
gi 639228517 494 EILTNAIRDYKGTLLVISHD----DVFSEEINI 522
Cdd:cd03236 179 ARLIRELAEDDNYVLVVEHDlavlDYLSDYIHC 211
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-184 |
7.23e-08 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 54.94 E-value: 7.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLtPSA---GDIRTEGSVYYLPQILeqfDT 77
Cdd:PRK13549 5 LLEMKNITKTFGGVKAL-DNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVY-PHGtyeGEIIFEGEELQASNIR---DT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 78 QS-----IARALGVQKKLSalreILEGIVTEENIT---VLDDNwDLEEKIKQALETWGlLDFTADESMNRLSGGQKTKVL 149
Cdd:PRK13549 80 ERagiaiIHQELALVKELS----VLENIFLGNEITpggIMDYD-AMYLRAQKLLAQLK-LDINPATPVGNLGLGQQQLVE 153
|
170 180 190
....*....|....*....|....*....|....*
gi 639228517 150 IAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN 184
Cdd:PRK13549 154 IAKALNKQARLLILDEPTASLTESETAVLLDIIRD 188
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
364-521 |
7.50e-08 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 53.18 E-value: 7.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 364 GERILIIGENGSGKTTLIKLLLGQMKPSEGTIeradfnsVYIDQDYSMIN-----HSLSVIQQAES-----------FNW 427
Cdd:PRK10247 33 GEFKLITGPSGCGKSTLLKIVASLISPTSGTL-------LFEGEDISTLKpeiyrQQVSYCAQTPTlfgdtvydnliFPW 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 428 L-----PLPEHEVKTiLSRFLFGKETWDKSCSVLSGGERMRL-LLACLSITgkaPDIIILDEPTNNLDLQNI----EILT 497
Cdd:PRK10247 106 QirnqqPDPAIFLDD-LERFALPDTILTKNIAELSGGEKQRIsLIRNLQFM---PKVLLLDEITSALDESNKhnvnEIIH 181
|
170 180
....*....|....*....|....
gi 639228517 498 NAIRDYKGTLLVISHDdvfSEEIN 521
Cdd:PRK10247 182 RYVREQNIAVLWVTHD---KDEIN 202
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
369-516 |
8.76e-08 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 54.64 E-value: 8.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 369 IIGENGSGKTTLIKLLLGQMKPSEGTI----ERADFNS-----------VYidQDYSMINHsLSViqqAEsfN-WLPlpe 432
Cdd:COG1129 35 LLGENGAGKSTLMKILSGVYQPDSGEIlldgEPVRFRSprdaqaagiaiIH--QELNLVPN-LSV---AE--NiFLG--- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 433 HEVKT--ILSRflfgKETWDKSCSVLsggERMRL------LLACLSIT-------GKA----PDIIILDEPTNNLDLQNI 493
Cdd:COG1129 104 REPRRggLIDW----RAMRRRARELL---ARLGLdidpdtPVGDLSVAqqqlveiARAlsrdARVLILDEPTASLTEREV 176
|
170 180
....*....|....*....|....*...
gi 639228517 494 EILTNAIRDYKG---TLLVISH--DDVF 516
Cdd:COG1129 177 ERLFRIIRRLKAqgvAIIYISHrlDEVF 204
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
2-171 |
9.98e-08 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 53.32 E-value: 9.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDK-EILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTpSAGDIRTEGSVYylpqilEQFDTQSI 80
Cdd:cd03289 3 MTVKDLTAKYTEGgNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSW------NSVPLQKW 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 81 ARALGV--QKKL---SALREILE--GIVTEENITVLDDNWDLEEKIKQALetwGLLDFTADESMNRLSGGQKTKVLIAGI 153
Cdd:cd03289 76 RKAFGVipQKVFifsGTFRKNLDpyGKWSDEEIWKVAEEVGLKSVIEQFP---GQLDFVLVDGGCVLSHGHKQLMCLARS 152
|
170
....*....|....*...
gi 639228517 154 EIHQPDIILMDEPTNHLD 171
Cdd:cd03289 153 VLSKAKILLLDEPSAHLD 170
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
337-503 |
1.21e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 53.27 E-value: 1.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGT-------IERADFNSVYI---- 405
Cdd:PRK13652 3 LIETRDLCYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSvlirgepITKENIREVRKfvgl 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 406 ------DQDYSminhslSVIQQAESFNWLPLP------EHEVKTILsRFLFGKETWDKSCSVLSGGERMRLLLAclSITG 473
Cdd:PRK13652 83 vfqnpdDQIFS------PTVEQDIAFGPINLGldeetvAHRVSSAL-HMLGLEELRDRVPHHLSGGEKKRVAIA--GVIA 153
|
170 180 190
....*....|....*....|....*....|
gi 639228517 474 KAPDIIILDEPTNNLDLQNIEILTNAIRDY 503
Cdd:PRK13652 154 MEPQVLVLDEPTAGLDPQGVKELIDFLNDL 183
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
432-512 |
1.29e-07 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 54.48 E-value: 1.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 432 EHEVKTILSRFLFGKETWDKSCSVLSGGERMRLLLA-CLSITgkaPDIIILDEPTNNLDLQNIEILTNAIRDYKGTLLVI 510
Cdd:PLN03073 321 EARAASILAGLSFTPEMQVKATKTFSGGWRMRIALArALFIE---PDLLLLDEPTNHLDLHAVLWLETYLLKWPKTFIVV 397
|
..
gi 639228517 511 SH 512
Cdd:PLN03073 398 SH 399
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
27-199 |
1.30e-07 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 51.22 E-value: 1.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 27 KGDKIAIVGNNGSGKSTLLKLISGLLTPsagdirTEGSVYYLpqileqfdtqsiaralgvqkklsalreilegivteeni 106
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGP------PGGGVIYI-------------------------------------- 36
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 107 tvlddnwDLEEKIKQALETWGLLDFTADESMnrLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTN 186
Cdd:smart00382 37 -------DGEDILEEVLDQLLLIIVGGKKAS--GSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELRL 107
|
170
....*....|...
gi 639228517 187 KTLLVVSHDRTLL 199
Cdd:smart00382 108 LLLLKSEKNLTVI 120
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
2-195 |
1.54e-07 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 51.93 E-value: 1.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNI-TYQHPDKEILFENLNfivnkgdkiAIVGNNGSGKSTLL---------------KLISGLLTPSAG------DI 59
Cdd:COG0419 5 LRLENFrSYRDTETIDFDDGLN---------LIVGPNGAGKSTILeairyalygkarsrsKLRSDLINVGSEeasvelEF 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 60 RTEGSVYYL--PQ--ILEQFDTQSIARAlgvqkklSALREILEGIVTEENITVLDD-NWDLEEKIKQA-----LETWGLL 129
Cdd:COG0419 76 EHGGKRYRIerRQgeFAEFLEAKPSERK-------EALKRLLGLEIYEELKERLKElEEALESALEELaelqkLKQEILA 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 130 DFTADESMNRLSGGQKTKVLIAgieihqpDIILMDEPTNHLDRQSREQLYEFIENtnktLLVVSHD 195
Cdd:COG0419 149 QLSGLDPIETLSGGERLRLALA-------DLLSLILDFGSLDEERLERLLDALEE----LAIITHV 203
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
32-218 |
1.68e-07 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 52.79 E-value: 1.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 32 AIVGNNGSGKSTLLKLISGLLTPSAGdIRTEGSVYYLPQ-ILEQFDTQSIARALGV--QKKLSALREILEGIVTEENITV 108
Cdd:PRK14271 51 SLMGPTGSGKTTFLRTLNRMNDKVSG-YRYSGDVLLGGRsIFNYRDVLEFRRRVGMlfQRPNPFPMSIMDNVLAGVRAHK 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 109 LDDNWDLEEKIKQALETWGLLDFTAD---ESMNRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENT 185
Cdd:PRK14271 130 LVPRKEFRGVAQARLTEVGLWDAVKDrlsDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSL 209
|
170 180 190
....*....|....*....|....*....|....*
gi 639228517 186 NK--TLLVVSHDrtllnlLPKTAELSRKEMMLYGG 218
Cdd:PRK14271 210 ADrlTVIIVTHN------LAQAARISDRAALFFDG 238
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
2-199 |
1.74e-07 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 51.48 E-value: 1.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEI---LFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPS--AGDIRTEGS---VYYLPQI-- 71
Cdd:cd03232 4 LTWKNLNYTVPVKGGkrqLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTAGviTGEILINGRpldKNFQRSTgy 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 72 LEQFDtqsiaralgvqkklsalreilegiVTEENITVlddnwdleekiKQALEtwglldFTADesmNR-LSGGQKTKVLI 150
Cdd:cd03232 84 VEQQD------------------------VHSPNLTV-----------REALR------FSAL---LRgLSVEQRKRLTI 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 639228517 151 aGIEI-HQPDIILMDEPTNHLDRQSREQLYEFIENtnktllVVSHDRTLL 199
Cdd:cd03232 120 -GVELaAKPSILFLDEPTSGLDSQAAYNIVRFLKK------LADSGQAIL 162
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-166 |
1.77e-07 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 52.34 E-value: 1.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG------SVY-------- 66
Cdd:COG1137 3 TLEAENLVKSYGKRTVV-KDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGedithlPMHkrarlgig 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 67 YLPQileqfdTQSIARALGVQKKLSALREILEgiVTEENItvlddnwdlEEKIKQALETWGLLDFtADESMNRLSGGQKT 146
Cdd:COG1137 82 YLPQ------EASIFRKLTVEDNILAVLELRK--LSKKER---------EERLEELLEEFGITHL-RKSKAYSLSGGERR 143
|
170 180
....*....|....*....|
gi 639228517 147 KVLIAGIEIHQPDIILMDEP 166
Cdd:COG1137 144 RVEIARALATNPKFILLDEP 163
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
334-527 |
2.23e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 52.40 E-value: 2.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 334 GKILIKAEHINHAYQDKNIWKKPL-----DVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTieradfnsVYIDQ- 407
Cdd:PRK13633 1 MNEMIKCKNVSYKYESNEESTEKLalddvNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGK--------VYVDGl 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 408 DYSMINHSLSVIQQA-----------------ESFNWLP----LPEHEVKTILSRFLFGKETW---DKSCSVLSGGERMR 463
Cdd:PRK13633 73 DTSDEENLWDIRNKAgmvfqnpdnqivativeEDVAFGPenlgIPPEEIRERVDESLKKVGMYeyrRHAPHLLSGGQKQR 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 464 LLLAclSITGKAPDIIILDEPTNNLDLQNIEILTNAIRD----YKGTLLVISHddvFSEEINIETRIL 527
Cdd:PRK13633 153 VAIA--GILAMRPECIIFDEPTAMLDPSGRREVVNTIKElnkkYGITIILITH---YMEEAVEADRII 215
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
357-491 |
2.29e-07 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 51.96 E-value: 2.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI----ERA------DFNSVYIDQDYSMINH---------SLS 417
Cdd:cd03296 21 VSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTIlfggEDAtdvpvqERNVGFVFQHYALFRHmtvfdnvafGLR 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 418 VIQQAESfnwlpLPEHEVKTILSRFL-FGKETW--DKSCSVLSGGERMRLLLA-CLSITgkaPDIIILDEPTNNLDLQ 491
Cdd:cd03296 101 VKPRSER-----PPEAEIRAKVHELLkLVQLDWlaDRYPAQLSGGQRQRVALArALAVE---PKVLLLDEPFGALDAK 170
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
338-504 |
2.48e-07 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 52.42 E-value: 2.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKniwkKPLDVV---VSSGErIL-IIGENGSGKTTLIKLLLGQMKPSEGTIEradfnsvyIDQ---DYS 410
Cdd:COG4152 2 LELKGLTKRFGDK----TAVDDVsftVPKGE-IFgLLGPNGAGKTTTIRIILGILAPDSGEVL--------WDGeplDPE 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 411 MINH------------SLSVIQQAESFNWLP-LPEHEVKTILSRFL--FG-KETWDKSCSVLSGGERMRLLLAClSITGK 474
Cdd:COG4152 69 DRRRigylpeerglypKMKVGEQLVYLARLKgLSKAEAKRRADEWLerLGlGDRANKKVEELSKGNQQKVQLIA-ALLHD 147
|
170 180 190
....*....|....*....|....*....|
gi 639228517 475 aPDIIILDEPTNNLDLQNIEILTNAIRDYK 504
Cdd:COG4152 148 -PELLILDEPFSGLDPVNVELLKDVIRELA 176
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
338-489 |
2.62e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 52.05 E-value: 2.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKP----LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADF--NSVYIDQDYSM 411
Cdd:PRK13649 3 INLQNVSYTYQAGTPFEGRalfdVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTliTSTSKNKDIKQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 412 INHSLSVIQQaesfnwlpLPEHEV--KTILSRFLFG-------------------------KETWDKSCSVLSGGERMRL 464
Cdd:PRK13649 83 IRKKVGLVFQ--------FPESQLfeETVLKDVAFGpqnfgvsqeeaealareklalvgisESLFEKNPFELSGGQMRRV 154
|
170 180
....*....|....*....|....*
gi 639228517 465 LLAclSITGKAPDIIILDEPTNNLD 489
Cdd:PRK13649 155 AIA--GILAMEPKILVLDEPTAGLD 177
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
337-512 |
2.91e-07 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 51.43 E-value: 2.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKKPLDVV---VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSV---------- 403
Cdd:cd03258 1 MIELKNVSKVFGDTGGKVTALKDVslsVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTllsgkelrka 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 404 -----YIDQDYSMINhSLSVIQQAEsfnwLPL-----PEHEVKTILSRF-----LFGKEtwDKSCSVLSGGERMRL---- 464
Cdd:cd03258 81 rrrigMIFQHFNLLS-SRTVFENVA----LPLeiagvPKAEIEERVLELlelvgLEDKA--DAYPAQLSGGQKQRVgiar 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 639228517 465 LLAClsitgkAPDIIILDEPTNNLDLQN----IEILTNAIRDYKGTLLVISH 512
Cdd:cd03258 154 ALAN------NPKVLLCDEATSALDPETtqsiLALLRDINRELGLTIVLITH 199
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
356-513 |
4.45e-07 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 49.67 E-value: 4.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 356 PLDVVVSSGERILIIGENGSGKTTLIK----LLLGQMKPSegtieradfnsvyidqdysminHSLSVIQQAesfnwlplp 431
Cdd:cd03227 13 PNDVTFGEGSLTIITGPNGSGKSTILDaiglALGGAQSAT----------------------RRRSGVKAG--------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 432 eHEVKTILSRFLFgketwdkSCSVLSGGER----MRLLLACLSITGKapDIIILDEPTNNLDLQNIEILTNAIRDY---K 504
Cdd:cd03227 62 -CIVAAVSAELIF-------TRLQLSGGEKelsaLALILALASLKPR--PLYILDEIDRGLDPRDGQALAEAILEHlvkG 131
|
....*....
gi 639228517 505 GTLLVISHD 513
Cdd:cd03227 132 AQVIVITHL 140
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1-111 |
4.46e-07 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 52.36 E-value: 4.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS--------------VY 66
Cdd:PRK15439 11 LLCARSISKQYSGVEVL-KGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNpcarltpakahqlgIY 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639228517 67 YLPQILEQFDTQSIA---------------------RALGVQKKLSA-----------LREILEGIVTEENITVLDD 111
Cdd:PRK15439 90 LVPQEPLLFPNLSVKenilfglpkrqasmqkmkqllAALGCQLDLDSsagslevadrqIVEILRGLMRDSRILILDE 166
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
327-512 |
5.10e-07 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 52.27 E-value: 5.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 327 DQANLHRGKILIKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradfnsvyID 406
Cdd:PRK13657 324 GAIDLGRVKGAVEFDDVSFSYDNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRIL--------ID 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 407 -QDYSMIN-----HSLSVI-QQAESFNwlplpehevKTILSRFLFGKET---------------WD-------------- 450
Cdd:PRK13657 396 gTDIRTVTraslrRNIAVVfQDAGLFN---------RSIEDNIRVGRPDatdeemraaaeraqaHDfierkpdgydtvvg 466
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 451 KSCSVLSGGERMRLLL--ACLsitgKAPDIIILDEPTNNLDLQNIEILTNAIRDY-KG-TLLVISH 512
Cdd:PRK13657 467 ERGRQLSGGERQRLAIarALL----KDPPILILDEATSALDVETEAKVKAALDELmKGrTTFIIAH 528
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
366-513 |
5.27e-07 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 50.88 E-value: 5.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 366 RIL-IIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSV-YIDQDYSM-INHSLSViqqaESFNWLP--LPEHEVKTILS 440
Cdd:PRK09544 31 KILtLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLRIgYVPQKLYLdTTLPLTV----NRFLRLRpgTKKEDILPALK 106
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639228517 441 RFLFGKeTWDKSCSVLSGGERMRLLLACLSITgkAPDIIILDEPTNNLDLQNIEILTNAIRDYKGTL----LVISHD 513
Cdd:PRK09544 107 RVQAGH-LIDAPMQKLSGGETQRVLLARALLN--RPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELdcavLMVSHD 180
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
364-512 |
6.84e-07 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 50.16 E-value: 6.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 364 GERILIIGENGSGKTTLIKLLLGQMKPSEGTI-----ERADFNSVYIDQDYSMINHSLSV----IQQAESFNWLPLPEHE 434
Cdd:cd03248 40 GEVTALVGPSGSGKSTVVALLENFYQPQGGQVlldgkPISQYEHKYLHSKVSLVGQEPVLfarsLQDNIAYGLQSCSFEC 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 435 VK---------TILSRFLFGKET-WDKSCSVLSGGERMRLLLACLSItgKAPDIIILDEPTNNLDLQNIEILTNAIRDY- 503
Cdd:cd03248 120 VKeaaqkahahSFISELASGYDTeVGEKGSQLSGGQKQRVAIARALI--RNPQVLILDEATSALDAESEQQVQQALYDWp 197
|
170
....*....|
gi 639228517 504 -KGTLLVISH 512
Cdd:cd03248 198 eRRTVLVIAH 207
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
337-512 |
7.46e-07 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 50.35 E-value: 7.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQdkniwKKPL--DVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGT--IERADFNSVYIDQ-DYSM 411
Cdd:PRK10771 1 MLKLTDITWLYH-----HLPMrfDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSltLNGQDHTTTPPSRrPVSM 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 412 InhslsvIQQAESFNWLPLPE-----------------HEVKTILSRfLFGKETWDKSCSVLSGGERMRLLLA-CLsiTG 473
Cdd:PRK10771 76 L------FQENNLFSHLTVAQniglglnpglklnaaqrEKLHAIARQ-MGIEDLLARLPGQLSGGQRQRVALArCL--VR 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 639228517 474 KAPdIIILDEPTNNLD--LQNiEILT---NAIRDYKGTLLVISH 512
Cdd:PRK10771 147 EQP-ILLLDEPFSALDpaLRQ-EMLTlvsQVCQERQLTLLMVSH 188
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
1-50 |
7.85e-07 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 50.41 E-value: 7.85e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISG 50
Cdd:CHL00131 7 ILEIKNLHASVNENEIL-KGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG 55
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
1-198 |
8.04e-07 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 50.60 E-value: 8.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSA--GDIRTEGSVYYLPQILEQFDTQ 78
Cdd:PRK13547 1 MLTADHLHVARRHRAIL-RDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGGapRGARVTGDVTLNGEPLAAIDAP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 SIARALGVQKKLS------ALREIL----------EGIVTEENITVLDdnwdleekikQALETWGlLDFTADESMNRLSG 142
Cdd:PRK13547 80 RLARLRAVLPQAAqpafafSAREIVllgrypharrAGALTHRDGEIAW----------QALALAG-ATALVGRDVTTLSG 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 143 GQKTKVLIAGI--EIHQPD-------IILMDEPTNHLDRQSREQLYEFIENTNKT----LLVVSHDRTL 198
Cdd:PRK13547 149 GELARVQFARVlaQLWPPHdaaqpprYLLLDEPTAALDLAHQHRLLDTVRRLARDwnlgVLAIVHDPNL 217
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
334-527 |
8.16e-07 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 49.35 E-value: 8.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 334 GKILIKAEHINHAYQDKNIwkkplDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADfNSVYIDQDYSMIN 413
Cdd:cd03215 1 GEPVLEVRGLSVKGAVRDV-----SFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDG-KPVTRRSPRDAIR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 414 HSLSVI----QQAESFNWLPLPEHevkTILSRFLfgketwdkscsvlSGGERMRLLLA-CLsitGKAPDIIILDEPTNNL 488
Cdd:cd03215 75 AGIAYVpedrKREGLVLDLSVAEN---IALSSLL-------------SGGNQQKVVLArWL---ARDPRVLILDEPTRGV 135
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 639228517 489 DLQNIEILTNAIRDYK---GTLLVISHDdvFSEEINIETRIL 527
Cdd:cd03215 136 DVGAKAEIYRLIRELAdagKAVLLISSE--LDELLGLCDRIL 175
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
335-502 |
8.48e-07 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 50.40 E-value: 8.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 335 KILIKAEHINHAYQdKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKL----------------LLGQMKPSEGT---- 394
Cdd:PRK09984 2 QTIIRVEKLAKTFN-QHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHlsglitgdksagshieLLGRTVQREGRlard 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 395 IERADFNSVYIDQDYSMINHsLSVIQQA------------ESFNWL-PLPEHEVKTILSRFLFGKETWDKsCSVLSGGER 461
Cdd:PRK09984 81 IRKSRANTGYIFQQFNLVNR-LSVLENVligalgstpfwrTCFSWFtREQKQRALQALTRVGMVHFAHQR-VSTLSGGQQ 158
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 639228517 462 MRLLLAcLSITGKApDIIILDEPTNNLDLQNIEILTNAIRD 502
Cdd:PRK09984 159 QRVAIA-RALMQQA-KVILADEPIASLDPESARIVMDTLRD 197
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
361-527 |
8.61e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 50.50 E-value: 8.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeradfnsvYIDQDYSM------INHSLSVIQQAESFNW------- 427
Cdd:PRK13650 30 VKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQI--------IIDGDLLTeenvwdIRHKIGMVFQNPDNQFvgatved 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 428 ----------LPLPEHEVKTILSRFLFGKETW-DKSCSVLSGGERMRLLLAclSITGKAPDIIILDEPTNNLD----LQN 492
Cdd:PRK13650 102 dvafglenkgIPHEEMKERVNEALELVGMQDFkEREPARLSGGQKQRVAIA--GAVAMRPKIIILDEATSMLDpegrLEL 179
|
170 180 190
....*....|....*....|....*....|....*
gi 639228517 493 IEILTNAIRDYKGTLLVISHDdvfSEEINIETRIL 527
Cdd:PRK13650 180 IKTIKGIRDDYQMTVISITHD---LDEVALSDRVL 211
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
329-528 |
8.74e-07 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 50.45 E-value: 8.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 329 ANLHRGKILIkAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQD 408
Cdd:PRK11247 5 ARLNQGTPLL-LNAVSKRYGERTVLNQ-LDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEARED 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 409 YSMInhslsvIQQAESFNWlplpehevKTILSRFLFG-KETWDKSC-----------------SVLSGGERMRLLLACLS 470
Cdd:PRK11247 83 TRLM------FQDARLLPW--------KKVIDNVGLGlKGQWRDAAlqalaavgladranewpAALSGGQKQRVALARAL 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639228517 471 ItgKAPDIIILDEPTNNLD-LQNIE---ILTNAIRDYKGTLLVISHDdvFSEEINIETRILL 528
Cdd:PRK11247 149 I--HRPGLLLLDEPLGALDaLTRIEmqdLIESLWQQHGFTVLLVTHD--VSEAVAMADRVLL 206
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
20-277 |
9.68e-07 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 52.05 E-value: 9.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTP-SAGDIRTEGSVYYLPQ------------IL--EQFDTQSIARAL 84
Cdd:PLN03130 635 NINLDVPVGSLVAIVGSTGEGKTSLISAMLGELPPrSDASVVIRGTVAYVPQvswifnatvrdnILfgSPFDPERYERAI 714
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 85 GVqkklSALREILEgivteenitvLDDNWDLEEkikqaletwglldfTADESMNrLSGGQKTKVLIAGIEIHQPDIILMD 164
Cdd:PLN03130 715 DV----TALQHDLD----------LLPGGDLTE--------------IGERGVN-ISGGQKQRVSMARAVYSNSDVYIFD 765
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 165 EPTNHLDRQSREQLYEFI---ENTNKTLLVVSHDrtlLNLLPKTAE--LSRKEMMLYGGNYDSYKEQ----KQIQQNA-- 233
Cdd:PLN03130 766 DPLSALDAHVGRQVFDKCikdELRGKTRVLVTNQ---LHFLSQVDRiiLVHEGMIKEEGTYEELSNNgplfQKLMENAgk 842
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 639228517 234 -----LQNSIKNTENALKKAKATERETlERQQKLDAKGKKKQEKAGVAK 277
Cdd:PLN03130 843 meeyvEENGEEEDDQTSSKPVANGNAN-NLKKDSSSKKKSKEGKSVLIK 890
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
354-510 |
1.17e-06 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 49.18 E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 354 KKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPS---EGTIEradFNSVYIDQDYSMINHSLSVIQQAESFNwlpl 430
Cdd:cd03233 23 LKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIH---YNGIPYKEFAEKYPGEIIYVSEEDVHF---- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 431 PEHEVktilsrflfgKETWDKSCS--------VLSGGERMRLLLACLSITGkaPDIIILDEPTNNLD----LQNIEILTN 498
Cdd:cd03233 96 PTLTV----------RETLDFALRckgnefvrGISGGERKRVSIAEALVSR--ASVLCWDNSTRGLDsstaLEILKCIRT 163
|
170
....*....|..
gi 639228517 499 AIRDYKGTLLVI 510
Cdd:cd03233 164 MADVLKTTTFVS 175
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1-184 |
1.18e-06 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 50.98 E-value: 1.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSA--GDIRTEGSVYYLPQI--LEQFD 76
Cdd:TIGR02633 1 LLEMKGIVKTFGGVKAL-DGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTwdGEIYWSGSPLKASNIrdTERAG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 77 TQSIARALGVQKKLSALREILEGIVTEENITVLDDNwDLEEKIKQALETWGLLDFTADESMNRLSGGQKTKVLIAGIEIH 156
Cdd:TIGR02633 80 IVIIHQELTLVPELSVAENIFLGNEITLPGGRMAYN-AMYLRAKNLLRELQLDADNVTRPVGDYGGGQQQLVEIAKALNK 158
|
170 180
....*....|....*....|....*...
gi 639228517 157 QPDIILMDEPTNHLDRQSREQLYEFIEN 184
Cdd:TIGR02633 159 QARLLILDEPSSSLTEKETEILLDIIRD 186
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
335-513 |
1.27e-06 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 50.48 E-value: 1.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 335 KILIKAEHINHAYQDKNIwKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI------------ERADFNS 402
Cdd:COG3842 3 MPALELENVSKRYGDVTA-LDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRIlldgrdvtglppEKRNVGM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 403 VYidQDYSMINHsLSViqqAE--SFnwlPL-----PEHEVKTILSRFL-------FGketwDKSCSVLSGGERMRLLLA- 467
Cdd:COG3842 82 VF--QDYALFPH-LTV---AEnvAF---GLrmrgvPKAEIRARVAELLelvglegLA----DRYPHQLSGGQQQRVALAr 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 639228517 468 CLSItgkAPDIIILDEPTNNLDLQNIEILTNAIRDY----KGTLLVISHD 513
Cdd:COG3842 149 ALAP---EPRVLLLDEPLSALDAKLREEMREELRRLqrelGITFIYVTHD 195
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
337-489 |
1.55e-06 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 49.10 E-value: 1.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGT-------IERADFNSV-YIDQD 408
Cdd:PRK10908 1 MIRFEHVSKAYLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKiwfsghdITRLKNREVpFLRRQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 409 YSMINHSLSVIQQAESFNWLPLP-------EHEVKTILSRFLFGKETWDKSCSV---LSGGERMRLLLAcLSITGKaPDI 478
Cdd:PRK10908 81 IGMIFQDHHLLMDRTVYDNVAIPliiagasGDDIRRRVSAALDKVGLLDKAKNFpiqLSGGEQQRVGIA-RAVVNK-PAV 158
|
170
....*....|.
gi 639228517 479 IILDEPTNNLD 489
Cdd:PRK10908 159 LLADEPTGNLD 169
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
357-484 |
1.71e-06 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 48.62 E-value: 1.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradfnsvyidqdysmINHSLS-VIQQAesfnWLpLPEhev 435
Cdd:cd03250 24 INLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVS---------------VPGSIAyVSQEP----WI-QNG--- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 436 kTILSRFLFGKEtWD--------KSCSV---------------------LSGGERMRLLLAclsitgKA----PDIIILD 482
Cdd:cd03250 81 -TIRENILFGKP-FDeeryekviKACALepdleilpdgdlteigekginLSGGQKQRISLA------RAvysdADIYLLD 152
|
..
gi 639228517 483 EP 484
Cdd:cd03250 153 DP 154
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
338-513 |
2.09e-06 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 49.21 E-value: 2.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIwKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGtieradfnSVYID----QDYSM-- 411
Cdd:PRK10253 8 LRGEQLTLGYGKYTV-AENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHG--------HVWLDgehiQHYASke 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 412 INHSLSVIQQaesfNWLPLPEHEVKTILSRFLFGKET----WDK---------------------SCSVLSGGERMRLLL 466
Cdd:PRK10253 79 VARRIGLLAQ----NATTPGDITVQELVARGRYPHQPlftrWRKedeeavtkamqatgithladqSVDTLSGGQRQRAWI 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 467 AClsITGKAPDIIILDEPTNNLDLQN----IEILTNAIRDYKGTLLVISHD 513
Cdd:PRK10253 155 AM--VLAQETAIMLLDEPTTWLDISHqidlLELLSELNREKGYTLAAVLHD 203
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-195 |
2.50e-06 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 49.46 E-value: 2.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG----------------- 63
Cdd:PRK11650 3 GLKLQAVRKSYDGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGrvvnelepadrdiamvf 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 64 ---------SVYylpqileqfdtQSIARAL---GVQKKlsalrEIlegivteenitvlddnwdlEEKIKQA---LETWGL 128
Cdd:PRK11650 83 qnyalyphmSVR-----------ENMAYGLkirGMPKA-----EI-------------------EERVAEAariLELEPL 127
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 129 LDftadesmnR----LSGGQKTKVLIAGIEIHQPDIILMDEPTNHLD---R-QSREQLYEFIENTNKTLLVVSHD 195
Cdd:PRK11650 128 LD--------RkpreLSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDaklRvQMRLEIQRLHRRLKTTSLYVTHD 194
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
338-513 |
3.06e-06 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 48.54 E-value: 3.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKkPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFN-SVYIDQDYSMInhsL 416
Cdd:COG4604 2 IEIKNVSKRYGGKVVLD-DVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDvATTPSRELAKR---L 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 417 SVIQQAESFNwlplpehevktilSRF------LFG----------KETW----------------DKSCSVLSGGERMRL 464
Cdd:COG4604 78 AILRQENHIN-------------SRLtvrelvAFGrfpyskgrltAEDReiideaiayldledlaDRYLDELSGGQRQRA 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 465 LLA---ClsitgKAPDIIILDEPTNNLDL----QNIEILTNAIRDYKGTLLVISHD 513
Cdd:COG4604 145 FIAmvlA-----QDTDYVLLDEPLNNLDMkhsvQMMKLLRRLADELGKTVVIVLHD 195
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
2-195 |
3.50e-06 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 49.64 E-value: 3.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqilEQFDTQSIA 81
Cdd:COG3845 258 LEVENLSVRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDG---------EDITGLSPR 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 --RALGV-------QKklsalreilEGIVTEENITvldDNWDLEEKIKQALETWGLLDFTA------------------- 133
Cdd:COG3845 329 erRRLGVayipedrLG---------RGLVPDMSVA---ENLILGRYRRPPFSRGGFLDRKAirafaeelieefdvrtpgp 396
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 134 DESMNRLSGG--QKtkvLIAGIEIHQ-PDIILMDEPTNHLDRQSREQLYEFI---ENTNKTLLVVSHD 195
Cdd:COG3845 397 DTPARSLSGGnqQK---VILARELSRdPKLLIAAQPTRGLDVGAIEFIHQRLlelRDAGAAVLLISED 461
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
356-525 |
3.81e-06 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 48.63 E-value: 3.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 356 PLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeradfnsVYIDQDYSMINHSLSVIQQAesfnWLP--LPEH 433
Cdd:PRK10575 29 PLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEI-------LLDAQPLESWSSKAFARKVA----YLPqqLPAA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 434 EVKTILSRFLFGKETW---------------DKSCSV-------------LSGGERMRLLLACLsiTGKAPDIIILDEPT 485
Cdd:PRK10575 98 EGMTVRELVAIGRYPWhgalgrfgaadrekvEEAISLvglkplahrlvdsLSGGERQRAWIAML--VAQDSRCLLLDEPT 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 639228517 486 NNLDL-QNIEILT--NAIRDYKG-TLLVISHDdvfseeINIETR 525
Cdd:PRK10575 176 SALDIaHQVDVLAlvHRLSQERGlTVIAVLHD------INMAAR 213
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
338-513 |
4.85e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 48.26 E-value: 4.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKniwKKP----LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQDYSM-I 412
Cdd:PRK13640 6 VEFKHVSFTYPDS---KKPalndISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPNSKITVDGITLTAKTVWdI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 413 NHSLSVIQQ---------------AESFNWLPLPEHEVKTILSRFL--FGKETWDKS-CSVLSGGERMRLLLAclSITGK 474
Cdd:PRK13640 83 REKVGIVFQnpdnqfvgatvgddvAFGLENRAVPRPEMIKIVRDVLadVGMLDYIDSePANLSGGQKQRVAIA--GILAV 160
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 639228517 475 APDIIILDEPTNNLDLQNIEILTNAIRDYKG----TLLVISHD 513
Cdd:PRK13640 161 EPKIIILDESTSMLDPAGKEQILKLIRKLKKknnlTVISITHD 203
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
361-512 |
5.06e-06 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 47.87 E-value: 5.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-------ERADFNSV-----YIDQDYSMINHSlsvIQQAESFNWL 428
Cdd:cd03252 25 IKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVlvdghdlALADPAWLrrqvgVVLQENVLFNRS---IRDNIALADP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 429 PLPEHEV---------KTILSRFLFGKETW-DKSCSVLSGGERMRLLLACLSITGkaPDIIILDEPTNNLDLQNIEILTN 498
Cdd:cd03252 102 GMSMERVieaaklagaHDFISELPEGYDTIvGEQGAGLSGGQRQRIAIARALIHN--PRILIFDEATSALDYESEHAIMR 179
|
170
....*....|....*.
gi 639228517 499 AIRDY-KG-TLLVISH 512
Cdd:cd03252 180 NMHDIcAGrTVIIIAH 195
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
360-489 |
5.55e-06 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 48.89 E-value: 5.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 360 VVSSGERILIIGENGSGKTTLIKLLLG-QMKPSEGT---------IERADFN--SVYIDQDySMINHSLSV----IQQAE 423
Cdd:TIGR00955 47 VAKPGELLAVMGSSGAGKTTLMNALAFrSPKGVKGSgsvllngmpIDAKEMRaiSAYVQQD-DLFIPTLTVrehlMFQAH 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 424 sfnwLPLPEHE--------VKTILSRF--------LFGKETWDKScsvLSGGERMRLLLACLSITGkaPDIIILDEPTNN 487
Cdd:TIGR00955 126 ----LRMPRRVtkkekrerVDEVLQALglrkcantRIGVPGRVKG---LSGGERKRLAFASELLTD--PPLLFCDEPTSG 196
|
..
gi 639228517 488 LD 489
Cdd:TIGR00955 197 LD 198
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
337-513 |
6.25e-06 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 47.58 E-value: 6.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-------------ERADFNSV 403
Cdd:PRK10895 3 TLTAKNLAKAYKGRRVVED-VSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIiiddedisllplhARARRGIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 404 YIDQDYSM---------------INHSLSVIQQAESFNWLpLPEHEVKTILsrflfgketwDKSCSVLSGGERMRLLLAc 468
Cdd:PRK10895 82 YLPQEASIfrrlsvydnlmavlqIRDDLSAEQREDRANEL-MEEFHIEHLR----------DSMGQSLSGGERRRVEIA- 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 639228517 469 lSITGKAPDIIILDEPTNNLD---LQNIEILTNAIRDYKGTLLVISHD 513
Cdd:PRK10895 150 -RALAANPKFILLDEPFAGVDpisVIDIKRIIEHLRDSGLGVLITDHN 196
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
357-512 |
6.67e-06 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 49.20 E-value: 6.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI-----ERADFNSVYIDQDYSMINHSLSVIQQAESFNWLPLP 431
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRImiddcDVAKFGLTDLRRVLSIIPQSPVLFSGTVRFNIDPFS 1334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 432 EH------------EVKTILSRFLFGKETwdkscSVLSGGERM----RLLLACLSITGKAPDIIILDEPTNNLDLQNIEI 495
Cdd:PLN03232 1335 EHndadlwealeraHIKDVIDRNPFGLDA-----EVSEGGENFsvgqRQLLSLARALLRRSKILVLDEATASVDVRTDSL 1409
|
170
....*....|....*....
gi 639228517 496 LTNAIR-DYKG-TLLVISH 512
Cdd:PLN03232 1410 IQRTIReEFKScTMLVIAH 1428
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
355-512 |
7.95e-06 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 48.63 E-value: 7.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 355 KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeradfnsVYIDQDYSMINHSLS-------VIQQAESFNW 427
Cdd:PRK09700 22 KSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTI-------TINNINYNKLDHKLAaqlgigiIYQELSVIDE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 428 LplpehevkTILSRFLFGKETWDKSCSV-LSGGERMR-----LLL------------ACLSITGKA-----------PDI 478
Cdd:PRK09700 95 L--------TVLENLYIGRHLTKKVCGVnIIDWREMRvraamMLLrvglkvdldekvANLSISHKQmleiaktlmldAKV 166
|
170 180 190
....*....|....*....|....*....|....*..
gi 639228517 479 IILDEPTNNLDLQNIEILTNAIRDYKG---TLLVISH 512
Cdd:PRK09700 167 IIMDEPTSSLTNKEVDYLFLIMNQLRKegtAIVYISH 203
|
|
| ABC_sbcCD |
cd03279 |
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ... |
368-520 |
8.05e-06 |
|
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.
Pssm-ID: 213246 [Multi-domain] Cd Length: 213 Bit Score: 46.88 E-value: 8.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 368 LIIGENGSGKTTLIK----LLLGQM--KPSEGTiERADFNS----VYIDQDYSMINHSLSVIQQ----AESF-NWLPLPE 432
Cdd:cd03279 32 LICGPTGAGKSTILDaityALYGKTprYGRQEN-LRSVFAPgedtAEVSFTFQLGGKKYRVERSrgldYDQFtRIVLLPQ 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 433 HEVKTILSRflfgketwdkSCSVLSGGERMRLLLAC-------LSITGKAP-DIIILDEPTNNLD---LQNIEILTNAIR 501
Cdd:cd03279 111 GEFDRFLAR----------PVSTLSGGETFLASLSLalalsevLQNRGGARlEALFIDEGFGTLDpeaLEAVATALELIR 180
|
170
....*....|....*....
gi 639228517 502 DYKGTLLVISHDDVFSEEI 520
Cdd:cd03279 181 TENRMVGVISHVEELKERI 199
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
1-200 |
1.01e-05 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 47.09 E-value: 1.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLlkliSGLLTPSAGDIRTEGSVYYLPQILEQFDTQS- 79
Cdd:PRK09580 1 MLSIKDLHVSVEDKAIL-RGLNLEVRPGEVHAIMGPNGSGKSTL----SATLAGREDYEVTGGTVEFKGKDLLELSPEDr 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 80 -----------------IARALGVQKKLSALREILEgivtEENITVLDDNWDLEEKIKqaletwgLLDFTAD---ESMNR 139
Cdd:PRK09580 76 agegifmafqypveipgVSNQFFLQTALNAVRSYRG----QEPLDRFDFQDLMEEKIA-------LLKMPEDlltRSVNV 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 140 -LSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI---ENTNKTLLVVSHDRTLLN 200
Cdd:PRK09580 145 gFSGGEKKRNDILQMAVLEPELCILDESDSGLDIDALKIVADGVnslRDGKRSFIIVTHYQRILD 209
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
355-512 |
1.18e-05 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 47.92 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 355 KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMkPSEGT-----IERADFNSVY------------------IDQDYSM 411
Cdd:PRK11174 367 GPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSlkingIELRELDPESwrkhlswvgqnpqlphgtLRDNVLL 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 412 INHSLS------VIQQAESFNWLPLPEHEVKTILSrflfgketwDKScSVLSGGERMRLLLAclSITGKAPDIIILDEPT 485
Cdd:PRK11174 446 GNPDASdeqlqqALENAWVSEFLPLLPQGLDTPIG---------DQA-AGLSVGQAQRLALA--RALLQPCQLLLLDEPT 513
|
170 180 190
....*....|....*....|....*....|.
gi 639228517 486 NNLDLQN----IEILTNAIRDYkgTLLVISH 512
Cdd:PRK11174 514 ASLDAHSeqlvMQALNAASRRQ--TTLMVTH 542
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
364-489 |
1.23e-05 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 47.52 E-value: 1.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 364 GERILIIGENGSGKTTLIKLLLGQMKPSEGTI--ERADFNSV--------YIDQDYSMINHsLSVIQQ-AESFNWLPLPE 432
Cdd:PRK11607 45 GEIFALLGASGCGKSTLLRMLAGFEQPTAGQImlDGVDLSHVppyqrpinMMFQSYALFPH-MTVEQNiAFGLKQDKLPK 123
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 433 HEVKTILSRFL---FGKETWDKSCSVLSGGERMRLLLAclSITGKAPDIIILDEPTNNLD 489
Cdd:PRK11607 124 AEIASRVNEMLglvHMQEFAKRKPHQLSGGQRQRVALA--RSLAKRPKLLLLDEPMGALD 181
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1-182 |
1.32e-05 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 47.90 E-value: 1.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPD--KEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGlltpsAGDIRTEGSVYYLPQileQFDTQ 78
Cdd:TIGR02633 257 ILEARNLTCWDVInpHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFG-----AYPGKFEGNVFINGK---PVDIR 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 SIARALGVQKKLSALREILEGIVTE----ENIT--VLD--------DNWDLEEKIKQALETWGLLDFTADESMNRLSGGQ 144
Cdd:TIGR02633 329 NPAQAIRAGIAMVPEDRKRHGIVPIlgvgKNITlsVLKsfcfkmriDAAAELQIIGSAIQRLKVKTASPFLPIGRLSGGN 408
|
170 180 190
....*....|....*....|....*....|....*...
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI 182
Cdd:TIGR02633 409 QQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLI 446
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
31-183 |
1.81e-05 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 47.43 E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 31 IAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG----------SVY----YLPQileqfdtqsiarALGvqkK-----LS 91
Cdd:NF033858 30 VGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGgdmadarhrrAVCpriaYMPQ------------GLG---KnlyptLS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 92 alreilegivTEENItvlD--------DNWDLEEKIKQALETWGLLDFtADESMNRLSGGQKTKVLIAGIEIHQPDIILM 163
Cdd:NF033858 95 ----------VFENL---DffgrlfgqDAAERRRRIDELLRATGLAPF-ADRPAGKLSGGMKQKLGLCCALIHDPDLLIL 160
|
170 180
....*....|....*....|
gi 639228517 164 DEPTNHLDRQSREQLYEFIE 183
Cdd:NF033858 161 DEPTTGVDPLSRRQFWELID 180
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
2-207 |
1.82e-05 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 46.72 E-value: 1.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 2 LTLQNITYQHPDKEIlfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLltpSAGDIRTEGSVYylpqileQFDTQSIA 81
Cdd:PRK15093 9 LTIEFKTSDGWVKAV--DRVSMTLTEGEIRGLVGESGSGKSLIAKAICGV---TKDNWRVTADRM-------RFDDIDLL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 82 RALGVQKKLSALREIleGIVTEENITVLDDNWDLEEKIKQALETW----------GLLDFTADESMNR------------ 139
Cdd:PRK15093 77 RLSPRERRKLVGHNV--SMIFQEPQSCLDPSERVGRQLMQNIPGWtykgrwwqrfGWRKRRAIELLHRvgikdhkdamrs 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 140 ----LSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI----ENTNKTLLVVSHDrtlLNLLPKTAE 207
Cdd:PRK15093 155 fpyeLTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLtrlnQNNNTTILLISHD---LQMLSQWAD 227
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
364-396 |
1.82e-05 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 46.46 E-value: 1.82e-05
10 20 30
....*....|....*....|....*....|...
gi 639228517 364 GERILIIGENGSGKTTLIKLLLGQMKPSEGTIE 396
Cdd:PRK11701 32 GEVLGIVGESGSGKTTLLNALSARLAPDAGEVH 64
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
333-512 |
1.83e-05 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 47.44 E-value: 1.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 333 RGKIL-----IKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLG--------QMKPSEGTIerad 399
Cdd:TIGR00954 442 RGIVEyqdngIKFENIPLVTPNGDVLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGElwpvyggrLTKPAKGKL---- 517
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 400 fnsVYIDQDYSMINHSL--SVI--QQAESFNWLPLPEHEVKTILS----RFLFGKE-TWDKSCS---VLSGGERMRLLLA 467
Cdd:TIGR00954 518 ---FYVPQRPYMTLGTLrdQIIypDSSEDMKRRGLSDKDLEQILDnvqlTHILEREgGWSAVQDwmdVLSGGEKQRIAMA 594
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 639228517 468 clSITGKAPDIIILDEPTNNLDLQNIEILTNAIRDYKGTLLVISH 512
Cdd:TIGR00954 595 --RLFYHKPQFAILDECTSAVSVDVEGYMYRLCREFGITLFSVSH 637
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
369-513 |
1.92e-05 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 46.19 E-value: 1.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 369 IIGENGSGKTTLIKLLLGQMKPSEGTIeRADFNSVYIDQDYSMIN------HSLSVIQQAESFNWL--------PLPEH- 433
Cdd:PRK14246 41 IMGPSGSGKSTLLKVLNRLIEIYDSKI-KVDGKVLYFGKDIFQIDaiklrkEVGMVFQQPNPFPHLsiydniayPLKSHg 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 434 -----EVKTILSRFL----FGKETWDK---SCSVLSGGERMRLLLAclSITGKAPDIIILDEPTNNLDLQNIEILTNAIR 501
Cdd:PRK14246 120 ikekrEIKKIVEECLrkvgLWKEVYDRlnsPASQLSGGQQQRLTIA--RALALKPKVLLMDEPTSMIDIVNSQAIEKLIT 197
|
170
....*....|....
gi 639228517 502 DYKG--TLLVISHD 513
Cdd:PRK14246 198 ELKNeiAIVIVSHN 211
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
18-203 |
1.93e-05 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 46.92 E-value: 1.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 18 FENLNFIVNKgDKIAIVGNNGSGKSTLLKLISGLLTPSAG------DIRTEGSVYYLPQILE-QFDT--QSIARALGVQK 88
Cdd:COG3593 14 IKDLSIELSD-DLTVLVGENNSGKSSILEALRLLLGPSSSrkfdeeDFYLGDDPDLPEIEIElTFGSllSRLLRLLLKEE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 89 KLSALREILEGIVTEenitvLDDNW-DLEEKIKQALETWGL-----LDFTADE------------------SMNRLSGGQ 144
Cdd:COG3593 93 DKEELEEALEELNEE-----LKEALkALNELLSEYLKELLDgldleLELSLDEledllkslslriedgkelPLDRLGSGF 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639228517 145 KTKVLIA-------GIEIHQPDIILMDEPTNHLDRQSREQLYEFIEN---TNKTLLVVSHDRTLLNLLP 203
Cdd:COG3593 168 QRLILLAllsalaeLKRAPANPILLIEEPEAHLHPQAQRRLLKLLKElseKPNQVIITTHSPHLLSEVP 236
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
361-512 |
1.99e-05 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 46.07 E-value: 1.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradfnsvyID----QDYSMinHSLS-----VIQQAESFNwlplp 431
Cdd:cd03251 25 IPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRIL--------IDghdvRDYTL--ASLRrqiglVSQDVFLFN----- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 432 ehevKTILSRFLFGK-------------------------ETWDKSC----SVLSGGERMRLLLACLSItgKAPDIIILD 482
Cdd:cd03251 90 ----DTVAENIAYGRpgatreeveeaaraanahefimelpEGYDTVIgergVKLSGGQRQRIAIARALL--KDPPILILD 163
|
170 180 190
....*....|....*....|....*....|..
gi 639228517 483 EPTNNLDLQNIEILTNAI-RDYKG-TLLVISH 512
Cdd:cd03251 164 EATSALDTESERLVQAALeRLMKNrTTFVIAH 195
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
20-194 |
2.12e-05 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 45.78 E-value: 2.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 20 NLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQILEQFDTQSIARALGVQKKLsalreiLEG 99
Cdd:cd03290 19 NINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRYSVAYAAQKPW------LLN 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 100 IVTEENIT-----------VLDDNWDLEEKIKqaLETWGLLDFTADESMNrLSGGQKTKVLIAGIEIHQPDIILMDEPTN 168
Cdd:cd03290 93 ATVEENITfgspfnkqrykAVTDACSLQPDID--LLPFGDQTEIGERGIN-LSGGQRQRICVARALYQNTNIVFLDDPFS 169
|
170 180 190
....*....|....*....|....*....|.
gi 639228517 169 HL-----DRQSREQLYEFIENTNKTLLVVSH 194
Cdd:cd03290 170 ALdihlsDHLMQEGILKFLQDDKRTLVLVTH 200
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
32-194 |
2.20e-05 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 46.79 E-value: 2.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 32 AIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileqFDTQSiARALGVQKklsalREIleGIVTEE------- 104
Cdd:PRK11144 28 AIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVL--------FDAEK-GICLPPEK-----RRI--GYVFQDarlfphy 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 105 ----NIT-----VLDDNWDleeKIKQALETWGLLD-FTAdesmnRLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQS 174
Cdd:PRK11144 92 kvrgNLRygmakSMVAQFD---KIVALLGIEPLLDrYPG-----SLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPR 163
|
170 180
....*....|....*....|....
gi 639228517 175 REQLYEFIENTNKTL----LVVSH 194
Cdd:PRK11144 164 KRELLPYLERLAREInipiLYVSH 187
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
355-512 |
3.58e-05 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 45.22 E-value: 3.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 355 KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradFNSVYI-DQDYSMINHSLSVIQQaES--FNwlplp 431
Cdd:cd03249 20 KGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEIL---LDGVDIrDLNLRWLRSQIGLVSQ-EPvlFD----- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 432 ehevKTILSRFLFGK-----ETWDKSC------------------------SVLSGGERMRLLLACLSItgKAPDIIILD 482
Cdd:cd03249 91 ----GTIAENIRYGKpdatdEEVEEAAkkanihdfimslpdgydtlvgergSQLSGGQKQRIAIARALL--RNPKILLLD 164
|
170 180 190
....*....|....*....|....*....|..
gi 639228517 483 EPTNNLDLQNIEILTNAI-RDYKG-TLLVISH 512
Cdd:cd03249 165 EATSALDAESEKLVQEALdRAMKGrTTIVIAH 196
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
369-513 |
3.80e-05 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 45.41 E-value: 3.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 369 IIGENGSGKTTLIKlLLGQMKPSEGTIE---RADF--NSVYIDQ-DYSMINHSLSVIQQAEsfNWLPL------------ 430
Cdd:PRK14258 38 IIGPSGCGKSTFLK-CLNRMNELESEVRvegRVEFfnQNIYERRvNLNRLRRQVSMVHPKP--NLFPMsvydnvaygvki 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 431 ----PEHEVKTILSRFLFGKETWD-------KSCSVLSGGERMRLLLA-CLSITgkaPDIIILDEPTNNLD---LQNIEI 495
Cdd:PRK14258 115 vgwrPKLEIDDIVESALKDADLWDeikhkihKSALDLSGGQQQRLCIArALAVK---PKVLLMDEPCFGLDpiaSMKVES 191
|
170
....*....|....*....
gi 639228517 496 LTNAIR-DYKGTLLVISHD 513
Cdd:PRK14258 192 LIQSLRlRSELTMVIVSHN 210
|
|
| COG3950 |
COG3950 |
Predicted ATP-binding protein involved in virulence [General function prediction only]; |
18-170 |
4.08e-05 |
|
Predicted ATP-binding protein involved in virulence [General function prediction only];
Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 45.37 E-value: 4.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 18 FENLNFIVNKGDKI-AIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS-----------------VYY---------LPQ 70
Cdd:COG3950 14 FEDLEIDFDNPPRLtVLVGENGSGKTTLLEAIALALSGLLSRLDDVKFrkllirngefgdsakliLYYgtsrllldgPLK 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 71 ILEQFDTQSIARALGVQKKLSA---LREILEGIVTEENITVLDDNWDLEEK-------IKQALETWGLLDFTADE----- 135
Cdd:COG3950 94 KLERLKEEYFSRLDGYDSLLDEdsnLREFLEWLREYLEDLENKLSDELDEKleavreaLNKLLPDFKDIRIDRDPgrlvi 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 639228517 136 --------SMNRLSGGQKTKVLIAG-----IEIHQPD---------IILMDEPTNHL 170
Cdd:COG3950 174 ldkngeelPLNQLSDGERSLLALVGdlarrLAELNPAlenplegegIVLIDEIDLHL 230
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
9-171 |
4.08e-05 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 46.70 E-value: 4.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 9 YQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQileqfdtQS-IARAlgvq 87
Cdd:PTZ00243 668 FELEPKVLL-RDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWAERSIAYVPQ-------QAwIMNA---- 735
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 88 kklsALRE-ILegIVTEENITVLDDN---WDLEEKIKQ---ALETwglldfTADESMNRLSGGQKTKVLIAGIEIHQPDI 160
Cdd:PTZ00243 736 ----TVRGnIL--FFDEEDAARLADAvrvSQLEADLAQlggGLET------EIGEKGVNLSGGQKARVSLARAVYANRDV 803
|
170
....*....|.
gi 639228517 161 ILMDEPTNHLD 171
Cdd:PTZ00243 804 YLLDDPLSALD 814
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
369-512 |
4.44e-05 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 44.48 E-value: 4.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 369 IIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQDY-SMINHSLSVIQQAESFNWLPLPE---HEVKTILSRFLF 444
Cdd:PRK13541 31 IKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIAKPYcTYIGHNLGLKLEMTVFENLKFWSeiyNSAETLYAAIHY 110
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639228517 445 GKET--WDKSCSVLSGGERMRL----LLACLSitgkapDIIILDEPTNNLDLQNIEILTNAI---RDYKGTLLVISH 512
Cdd:PRK13541 111 FKLHdlLDEKCYSLSSGMQKIVaiarLIACQS------DLWLLDEVETNLSKENRDLLNNLIvmkANSGGIVLLSSH 181
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
355-409 |
4.63e-05 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 45.17 E-value: 4.63e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 355 KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQDY 409
Cdd:PRK15112 30 KPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSY 84
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
361-513 |
5.15e-05 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 45.52 E-value: 5.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradFNS--VYID------------QDYSMINHsLSVIQQ-AESF 425
Cdd:COG1118 25 IASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIV---LNGrdLFTNlpprerrvgfvfQHYALFPH-MTVAENiAFGL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 426 NWLPLPEHEVKTILSRFL-------FGketwDKSCSVLSGGERMRLLLAclsitgKA----PDIIILDEPTNNLDLQnie 494
Cdd:COG1118 101 RVRPPSKAEIRARVEELLelvqlegLA----DRYPSQLSGGQRQRVALA------RAlavePEVLLLDEPFGALDAK--- 167
|
170 180
....*....|....*....|....*..
gi 639228517 495 iLTNAIR--------DYKGTLLVISHD 513
Cdd:COG1118 168 -VRKELRrwlrrlhdELGGTTVFVTHD 193
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
140-221 |
5.99e-05 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 46.18 E-value: 5.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 140 LSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSrEQLYEfientnKTLLVVSH--DRTLLNLLPKTAELSRKEMMLYG 217
Cdd:PTZ00265 1359 LSGGQKQRIAIARALLREPKILLLDEATSSLDSNS-EKLIE------KTIVDIKDkaDKTIITIAHRIASIKRSDKIVVF 1431
|
....
gi 639228517 218 GNYD 221
Cdd:PTZ00265 1432 NNPD 1435
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
19-195 |
6.72e-05 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 44.90 E-value: 6.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPS----AGDIRtegsvyylpqileqFDTQSIARALGVQKKLSALR 94
Cdd:COG4170 24 DRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNwhvtADRFR--------------WNGIDLLKLSPRERRKIIGR 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 95 EIleGIVTEENITVLDDNWDLEEKIKQALETWGLLDF----------TADESMNR----------------LSGGQKTKV 148
Cdd:COG4170 90 EI--AMIFQEPSSCLDPSAKIGDQLIEAIPSWTFKGKwwqrfkwrkkRAIELLHRvgikdhkdimnsypheLTEGECQKV 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 149 LIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK----TLLVVSHD 195
Cdd:COG4170 168 MIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQlqgtSILLISHD 218
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
338-528 |
8.29e-05 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 44.21 E-value: 8.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradFNSVYI-DQDYSMINHSL 416
Cdd:cd03295 1 IEFENVTKRYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIF---IDGEDIrEQDPVELRRKI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 417 S-VIQQ---------AESFNWLP----LPEHEVKTILSRFLF-----GKETWDKSCSVLSGGERMRLLLAclsitgKA-- 475
Cdd:cd03295 78 GyVIQQiglfphmtvEENIALVPkllkWPKEKIRERADELLAlvgldPAEFADRYPHELSGGQQQRVGVA------RAla 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 639228517 476 --PDIIILDEPTNNLD------LQniEILTNAIRDYKGTLLVISHDdvFSEEINIETRILL 528
Cdd:cd03295 152 adPPLLLMDEPFGALDpitrdqLQ--EEFKRLQQELGKTIVFVTHD--IDEAFRLADRIAI 208
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
338-513 |
8.48e-05 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 44.34 E-value: 8.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 338 IKAEHINHAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE--------------RADFNSV 403
Cdd:PRK13647 5 IEVEDLHFRYKDGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKvmgrevnaenekwvRSKVGLV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 404 YIDQDYSMINhslSVIQQAESF---NwLPLPEHEVKTILSRFLFGKETWD---KSCSVLSGGERMRLLLAclSITGKAPD 477
Cdd:PRK13647 85 FQDPDDQVFS---STVWDDVAFgpvN-MGLDKDEVERRVEEALKAVRMWDfrdKPPYHLSYGQKKRVAIA--GVLAMDPD 158
|
170 180 190
....*....|....*....|....*....|....*....
gi 639228517 478 IIILDEPTNNLDLQNIEILT---NAIRDYKGTLLVISHD 513
Cdd:PRK13647 159 VIVLDEPMAYLDPRGQETLMeilDRLHNQGKTVIVATHD 197
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
357-513 |
8.66e-05 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 44.31 E-value: 8.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE-------------RADFNS-VYidQDYSM-INHSLSVIQ- 420
Cdd:COG1101 25 LNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILidgkdvtklpeykRAKYIGrVF--QDPMMgTAPSMTIEEn 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 421 --------QAESFNWLPLPEH--EVKTILSRFLFGKET-WDKSCSVLSGGER--MRLLLACLsitgKAPDIIILDEPTNN 487
Cdd:COG1101 103 lalayrrgKRRGLRRGLTKKRreLFRELLATLGLGLENrLDTKVGLLSGGQRqaLSLLMATL----TKPKLLLLDEHTAA 178
|
170 180 190
....*....|....*....|....*....|
gi 639228517 488 LDLQNIEI---LTN-AIRDYKGTLLVISHD 513
Cdd:COG1101 179 LDPKTAALvleLTEkIVEENNLTTLMVTHN 208
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
371-516 |
8.84e-05 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 44.90 E-value: 8.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 371 GENGSGKTTLIKLLLGQMKPSEGTI----ERADFNSVyidqdYSMINHSLSVIQQAesfnwLPL-PEHEV-KTILSRFLF 444
Cdd:PRK11288 37 GENGAGKSTLLKILSGNYQPDAGSIlidgQEMRFAST-----TAALAAGVAIIYQE-----LHLvPEMTVaENLYLGQLP 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 445 GKETW-DKSCSVLSGGERMRLL---------LACLSI-------TGKA----PDIIILDEPTNNLDLQNIEILTNAIRDY 503
Cdd:PRK11288 107 HKGGIvNRRLLNYEAREQLEHLgvdidpdtpLKYLSIgqrqmveIAKAlarnARVIAFDEPTSSLSAREIEQLFRVIREL 186
|
170
....*....|....*...
gi 639228517 504 K--GT-LLVISH--DDVF 516
Cdd:PRK11288 187 RaeGRvILYVSHrmEEIF 204
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
32-188 |
1.24e-04 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 44.84 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 32 AIVGNNGSGKSTLLKLISGLLTPS--AGDIRTEGsvyyLPQILEQFdtqsiARALG-------------VQKKL--SALR 94
Cdd:PLN03140 910 ALMGVSGAGKTTLMDVLAGRKTGGyiEGDIRISG----FPKKQETF-----ARISGyceqndihspqvtVRESLiySAFL 980
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 95 EILEGIVTEENITVLDDNWDLEE--KIKQALEtwGLLDFTAdesmnrLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDR 172
Cdd:PLN03140 981 RLPKEVSKEEKMMFVDEVMELVEldNLKDAIV--GLPGVTG------LSTEQRKRLTIAVELVANPSIIFMDEPTSGLDA 1052
|
170
....*....|....*.
gi 639228517 173 QSREQLYEFIENTNKT 188
Cdd:PLN03140 1053 RAAAIVMRTVRNTVDT 1068
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
12-194 |
1.25e-04 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 44.94 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 12 PDKEILFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvyylpqileqfdtqsiaraLGVQK-KL 90
Cdd:TIGR00957 1296 EDLDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDG--------------------LNIAKiGL 1355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 91 SALREILEgIVTEENITV---LDDNWD-----LEEKIKQALETWGL----------LDFTADESMNRLSGGQKTKVLIAG 152
Cdd:TIGR00957 1356 HDLRFKIT-IIPQDPVLFsgsLRMNLDpfsqySDEEVWWALELAHLktfvsalpdkLDHECAEGGENLSVGQRQLVCLAR 1434
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 639228517 153 IEIHQPDIILMDEPTNHLDRQSREQLYEFIENT--NKTLLVVSH 194
Cdd:TIGR00957 1435 ALLRKTKILVLDEATAAVDLETDNLIQSTIRTQfeDCTVLTIAH 1478
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1-182 |
1.27e-04 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 44.61 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGS--VYYLPQILEQFDTQ 78
Cdd:PRK10762 4 LLQLKGIDKAFPGVKAL-SGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKevTFNGPKSSQEAGIG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 79 SIARALGVQKKLSALREILEG--IVTEENITVLDDNWDLEEKIKQALEtwglLDFTADESMNRLSGGQKTKVLIAGIEIH 156
Cdd:PRK10762 83 IIHQELNLIPQLTIAENIFLGreFVNRFGRIDWKKMYAEADKLLARLN----LRFSSDKLVGELSIGEQQMVEIAKVLSF 158
|
170 180
....*....|....*....|....*.
gi 639228517 157 QPDIILMDEPTNHLDRQSREQLYEFI 182
Cdd:PRK10762 159 ESKVIIMDEPTDALTDTETESLFRVI 184
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
19-183 |
1.36e-04 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 44.34 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileQFDTQSIARALGVQKKLSALREILE 98
Cdd:PRK10982 15 DNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEI-------DFKSSKEALENGISMVHQELNLVLQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 99 givteenITVLDDNW-----------DLEEKIKQALETWGLLDFTAD--ESMNRLSGGQKTKVLIAGIEIHQPDIILMDE 165
Cdd:PRK10982 88 -------RSVMDNMWlgryptkgmfvDQDKMYRDTKAIFDELDIDIDprAKVATLSVSQMQMIEIAKAFSYNAKIVIMDE 160
|
170
....*....|....*...
gi 639228517 166 PTNHLDRQSREQLYEFIE 183
Cdd:PRK10982 161 PTSSLTEKEVNHLFTIIR 178
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
355-490 |
1.42e-04 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 44.90 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 355 KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradfnsvyidqdysminHSlSVIQQAESFNWLpLPehe 434
Cdd:TIGR01271 443 KNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIK-----------------HS-GRISFSPQTSWI-MP--- 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 435 vKTILSRFLFGKeTWD--------KSCSV---------------------LSGGERMRLLLAclSITGKAPDIIILDEPT 485
Cdd:TIGR01271 501 -GTIKDNIIFGL-SYDeyrytsviKACQLeedialfpekdktvlgeggitLSGGQRARISLA--RAVYKDADLYLLDSPF 576
|
....*
gi 639228517 486 NNLDL 490
Cdd:TIGR01271 577 THLDV 581
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
367-513 |
1.52e-04 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 43.08 E-value: 1.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 367 ILIIGENGSGKTTL---IKLLLGqMKPSEGTIERADF-----NSVYIDQDYSMINHSLSVI-QQAESFNWLPLPEHEVKT 437
Cdd:COG0419 26 NLIVGPNGAGKSTIleaIRYALY-GKARSRSKLRSDLinvgsEEASVELEFEHGGKRYRIErRQGEFAEFLEAKPSERKE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 438 ILSRfLFGKETWDK-------------------------------------SCSVLSGGERMRLLLACLSitgkapdIII 480
Cdd:COG0419 105 ALKR-LLGLEIYEElkerlkeleealesaleelaelqklkqeilaqlsgldPIETLSGGERLRLALADLL-------SLI 176
|
170 180 190
....*....|....*....|....*....|...
gi 639228517 481 LDepTNNLDLQNIEILTNAIRDykgtLLVISHD 513
Cdd:COG0419 177 LD--FGSLDEERLERLLDALEE----LAIITHV 203
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
1-65 |
1.59e-04 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 44.40 E-value: 1.59e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 1 MLTLQNITYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLtPSA---GDIRTEGSV 65
Cdd:NF040905 1 ILEMRGITKTFPGVKAL-DDVNLSVREGEIHALCGENGAGKSTLMKVLSGVY-PHGsyeGEILFDGEV 66
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
334-489 |
1.67e-04 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 43.78 E-value: 1.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 334 GKILIKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI------------ERADFN 401
Cdd:PRK09452 11 LSPLVELRGISKSFDGKEVISN-LDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRImldgqdithvpaENRHVN 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 402 SVYidQDYSMINHsLSVIQQ-AESFNWLPLPEHEVKTILS---RFLFGKETWDKSCSVLSGGERMRLLLAcLSITGKaPD 477
Cdd:PRK09452 90 TVF--QSYALFPH-MTVFENvAFGLRMQKTPAAEITPRVMealRMVQLEEFAQRKPHQLSGGQQQRVAIA-RAVVNK-PK 164
|
170
....*....|..
gi 639228517 478 IIILDEPTNNLD 489
Cdd:PRK09452 165 VLLLDESLSALD 176
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
392-513 |
2.01e-04 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 44.23 E-value: 2.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 392 EGTIERADFNSVYID----QDYSminhSLSVIQQAESFNWLPLPEHE-------VKTILSRFLFGKE------TWDKSCS 454
Cdd:TIGR00630 412 GGTRLKPEALAVTVGgksiADVS----ELSIREAHEFFNQLTLTPEEkkiaeevLKEIRERLGFLIDvgldylSLSRAAG 487
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639228517 455 VLSGGERMRLLLACLSITGKAPDIIILDEPTNNLDLQN----IEILTNaIRDYKGTLLVISHD 513
Cdd:TIGR00630 488 TLSGGEAQRIRLATQIGSGLTGVLYVLDEPSIGLHQRDnrrlINTLKR-LRDLGNTLIVVEHD 549
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
18-195 |
2.05e-04 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 43.89 E-value: 2.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 18 FENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDI--------------RTEGSVYYLPQileqfDTQSiara 83
Cdd:PRK15439 279 FRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRImlngkeinalstaqRLARGLVYLPE-----DRQS---- 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 84 lgvqkklSALreILEGIVTEeNITVLDDN----WDLEEKIKQALETW----GLLDFTADESMNRLSGGQKTKVLIAGIEI 155
Cdd:PRK15439 350 -------SGL--YLDAPLAW-NVCALTHNrrgfWIKPARENAVLERYrralNIKFNHAEQAARTLSGGNQQKVLIAKCLE 419
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 639228517 156 HQPDIILMDEPTNHLDRQSREQLYEFIENT---NKTLLVVSHD 195
Cdd:PRK15439 420 ASPQLLIVDEPTRGVDVSARNDIYQLIRSIaaqNVAVLFISSD 462
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
357-512 |
2.16e-04 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 44.05 E-value: 2.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradFNSVYIdQDYS--MINHSLSVI-QQAESFN------- 426
Cdd:PRK11160 359 LSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEIL---LNGQPI-ADYSeaALRQAISVVsQRVHLFSatlrdnl 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 427 WLPLP---EHEVKTILSRFLFGK--ETwDKSCSV--------LSGGERMRLLLA--CLSitgKAPdIIILDEPTNNLDLQ 491
Cdd:PRK11160 435 LLAAPnasDEALIEVLQQVGLEKllED-DKGLNAwlgeggrqLSGGEQRRLGIAraLLH---DAP-LLLLDEPTEGLDAE 509
|
170 180
....*....|....*....|...
gi 639228517 492 N-IEILTNAIRDYKG-TLLVISH 512
Cdd:PRK11160 510 TeRQILELLAEHAQNkTVLMITH 532
|
|
| ABC_tran_Xtn |
pfam12848 |
ABC transporter; This domain is an extension of some members of pfam00005 and other ... |
206-271 |
2.44e-04 |
|
ABC transporter; This domain is an extension of some members of pfam00005 and other ABC-transporter families.
Pssm-ID: 463731 [Multi-domain] Cd Length: 85 Bit Score: 39.86 E-value: 2.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 206 AELSRKEMMLYGGNYDSYKEQKQIQQNAL-------QNSIKNTE--------NALKKAKATERET-LERQQKLDAKGKKK 269
Cdd:pfam12848 1 VELERGKLTTYKGNYSTFLEQKEERLEQQekayekqQKEIKKLEefidrfraKASKAKQAQSRIKaLEKMERIEKPERDK 80
|
..
gi 639228517 270 QE 271
Cdd:pfam12848 81 PK 82
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
361-513 |
2.56e-04 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 42.67 E-value: 2.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeRADFNSVYIDQDYSMINH-------------SLSVIQqaesfNW 427
Cdd:PRK11300 28 VREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTI-LLRGQHIEGLPGHQIARMgvvrtfqhvrlfrEMTVIE-----NL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 428 LPLPEHEVKTILSRFLFG--------------KETW----------DKSCSVLSGGERMRLLLACLSITGkaPDIIILDE 483
Cdd:PRK11300 102 LVAQHQQLKTGLFSGLLKtpafrraesealdrAATWlervgllehaNRQAGNLAYGQQRRLEIARCMVTQ--PEILMLDE 179
|
170 180 190
....*....|....*....|....*....|....
gi 639228517 484 PTNNLDLQNIEILTNAI----RDYKGTLLVISHD 513
Cdd:PRK11300 180 PAAGLNPKETKELDELIaelrNEHNVTVLLIEHD 213
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
360-489 |
3.19e-04 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 43.33 E-value: 3.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 360 VVSSGERILIIGENGSGKTTLIKLLLGQM--------------KPSEGTIERADFnsvyIDQDYSMINHsLSVIQQAESF 425
Cdd:PLN03211 90 MASPGEILAVLGPSGSGKSTLLNALAGRIqgnnftgtilannrKPTKQILKRTGF----VTQDDILYPH-LTVRETLVFC 164
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 426 NWLPLPE---HEVKTILSRFLFGKETWDKSCSV---------LSGGERMRLLLACLSITGkaPDIIILDEPTNNLD 489
Cdd:PLN03211 165 SLLRLPKsltKQEKILVAESVISELGLTKCENTiignsfirgISGGERKRVSIAHEMLIN--PSLLILDEPTSGLD 238
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
19-193 |
3.88e-04 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 43.18 E-value: 3.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 19 ENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYylpqileqfdtqsiaralgvqKKLSALREILE 98
Cdd:PRK10982 265 RDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKI---------------------NNHNANEAINH 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 99 G--IVTEEN-ITVLDDNWDLE-----EKIKQALETWGLLD---FTAD-----ESMN-----------RLSGGQKTKVLIA 151
Cdd:PRK10982 324 GfaLVTEERrSTGIYAYLDIGfnsliSNIRNYKNKVGLLDnsrMKSDtqwviDSMRvktpghrtqigSLSGGNQQKVIIG 403
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 639228517 152 GIEIHQPDIILMDEPTNHLDRQSREQLYEFI---ENTNKTLLVVS 193
Cdd:PRK10982 404 RWLLTQPEILMLDEPTRGIDVGAKFEIYQLIaelAKKDKGIIIIS 448
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
355-512 |
3.98e-04 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 43.40 E-value: 3.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 355 KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIeRAD-------------FNSVYIDQDYSMINHSLSV--- 418
Cdd:TIGR00957 1303 RHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEI-IIDglniakiglhdlrFKITIIPQDPVLFSGSLRMnld 1381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 419 --IQQAESFNWLPLPEHEVKTILSRFlfgKETWDKSCSvlSGGERMRL---LLACLS-ITGKAPDIIILDEPTNNLDLQN 492
Cdd:TIGR00957 1382 pfSQYSDEEVWWALELAHLKTFVSAL---PDKLDHECA--EGGENLSVgqrQLVCLArALLRKTKILVLDEATAAVDLET 1456
|
170 180
....*....|....*....|..
gi 639228517 493 IEILTNAIRDY--KGTLLVISH 512
Cdd:TIGR00957 1457 DNLIQSTIRTQfeDCTVLTIAH 1478
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
8-178 |
4.11e-04 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 43.16 E-value: 4.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 8 TYQHPDKEILfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGsvYYLPQIleQFD----------- 76
Cdd:PRK10789 322 TYPQTDHPAL-ENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHD--IPLTKL--QLDswrsrlavvsq 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 77 -----TQSIAR--ALGvqkKLSALREILEGIVTEENitVLDDNWDLEEKIKQALETWGLLdftadesmnrLSGGQKTKVL 149
Cdd:PRK10789 397 tpflfSDTVANniALG---RPDATQQEIEHVARLAS--VHDDILRLPQGYDTEVGERGVM----------LSGGQKQRIS 461
|
170 180
....*....|....*....|....*....
gi 639228517 150 IAGIEIHQPDIILMDEPTNHLDRQSREQL 178
Cdd:PRK10789 462 IARALLLNAEILILDDALSAVDGRTEHQI 490
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
121-199 |
4.26e-04 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 41.15 E-value: 4.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 121 QALETWGLLDFTADESMNRLSGGQKTKVLIA---GIEIHqPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSH 194
Cdd:cd03238 69 QFLIDVGLGYLTLGQKLSTLSGGELQRVKLAselFSEPP-GTLFILDEPSTGLHQQDINQLLEVIKgliDLGNTVILIEH 147
|
....*
gi 639228517 195 DRTLL 199
Cdd:cd03238 148 NLDVL 152
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
369-512 |
4.72e-04 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 42.07 E-value: 4.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 369 IIGENGSGKTTLIKLL--LGQMKPSEGTIERADFN----------SVYIDQDYSMinhslsVIQQAESFnwlPLPEHEV- 435
Cdd:PRK14239 36 LIGPSGSGKSTLLRSInrMNDLNPEVTITGSIVYNghniysprtdTVDLRKEIGM------VFQQPNPF---PMSIYENv 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 436 -----------KTIL----SRFLFGKETWDK-------SCSVLSGGERMRLLLAclSITGKAPDIIILDEPTNNLD---L 490
Cdd:PRK14239 107 vyglrlkgikdKQVLdeavEKSLKGASIWDEvkdrlhdSALGLSGGQQQRVCIA--RVLATSPKIILLDEPTSALDpisA 184
|
170 180
....*....|....*....|..
gi 639228517 491 QNIEILTNAIRDyKGTLLVISH 512
Cdd:PRK14239 185 GKIEETLLGLKD-DYTMLLVTR 205
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
370-489 |
4.83e-04 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 43.08 E-value: 4.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 370 IGENGSGKTTLIKLLLGQMKPSEGTIERADFNsvyIDQDYSMINHSLSVIQQAES-FNWLPLPEHevktILSRFLFGKET 448
Cdd:TIGR01257 962 LGHNGAGKTTTLSILTGLLPPTSGTVLVGGKD---IETNLDAVRQSLGMCPQHNIlFHHLTVAEH----ILFYAQLKGRS 1034
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 639228517 449 WDKS--------------------CSVLSGGERMRLLLAcLSITGKApDIIILDEPTNNLD 489
Cdd:TIGR01257 1035 WEEAqlemeamledtglhhkrneeAQDLSGGMQRKLSVA-IAFVGDA-KVVVLDEPTSGVD 1093
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
355-490 |
5.05e-04 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 42.15 E-value: 5.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 355 KPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIEradfnsvyidqdysminHSlSVIQQAESFNWLpLPehe 434
Cdd:cd03291 54 KNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIK-----------------HS-GRISFSSQFSWI-MP--- 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 435 vKTILSRFLFGKeTWD--------KSCSV---------------------LSGGERMRLLLAclSITGKAPDIIILDEPT 485
Cdd:cd03291 112 -GTIKENIIFGV-SYDeyryksvvKACQLeeditkfpekdntvlgeggitLSGGQRARISLA--RAVYKDADLYLLDSPF 187
|
....*
gi 639228517 486 NNLDL 490
Cdd:cd03291 188 GYLDV 192
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
454-513 |
5.12e-04 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 42.89 E-value: 5.12e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639228517 454 SVLSGGERMRLLLAC-LSITGKAPDIIILDEPTNNLDLQNIEILTNAIRD--YKG-TLLVISHD 513
Cdd:PRK00635 808 SSLSGGEIQRLKLAYeLLAPSKKPTLYVLDEPTTGLHTHDIKALIYVLQSltHQGhTVVIIEHN 871
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
456-515 |
5.34e-04 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 41.83 E-value: 5.34e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 456 LSGGERMRLLLAC-LSITGKAPDIIILDEPTNNLDLQNIEILTNAIRD--YKG-TLLVISHD-DV 515
Cdd:cd03271 170 LSGGEAQRIKLAKeLSKRSTGKTLYILDEPTTGLHFHDVKKLLEVLQRlvDKGnTVVVIEHNlDV 234
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
324-395 |
7.78e-04 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 41.40 E-value: 7.78e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639228517 324 LGFDQANLHRGKIliKAEHinhayqdkniwkkPLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTI 395
Cdd:PRK11614 6 LSFDKVSAHYGKI--QALH-------------EVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRI 62
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
337-513 |
7.93e-04 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 41.22 E-value: 7.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 337 LIKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE---------RADFNSVYID- 406
Cdd:PRK11248 1 MLQISHLYADYGGKPALED-INLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITldgkpvegpGAERGVVFQNe 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 407 --------QDYSMINHSLSVIQQAESfnwlplpEHEVKTILSRF-LFGKET---WDkscsvLSGGERMRLLLAclSITGK 474
Cdd:PRK11248 80 gllpwrnvQDNVAFGLQLAGVEKMQR-------LEIAHQMLKKVgLEGAEKryiWQ-----LSGGQRQRVGIA--RALAA 145
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 639228517 475 APDIIILDEPTNNLDL----QNIEILTNAIRDYKGTLLVISHD 513
Cdd:PRK11248 146 NPQLLLLDEPFGALDAftreQMQTLLLKLWQETGKQVLLITHD 188
|
|
| CpaF |
COG4962 |
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ... |
357-398 |
8.01e-04 |
|
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 443988 [Multi-domain] Cd Length: 386 Bit Score: 41.69 E-value: 8.01e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSE--GTIERA 398
Cdd:COG4962 175 LRAAVRARLNILVSGGTGSGKTTLLNALSGFIPPDEriVTIEDA 218
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
76-180 |
9.56e-04 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 41.64 E-value: 9.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 76 DTQSIARALGVQKKLSALREilEGIVTEENITVLDDNWDLEEKIKQALETWGLLDFTADESMNR----LSGGQKTKVLIA 151
Cdd:NF000106 79 NRRALRRTIG*HRPVR*GRR--ESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRaaakYSGGMRRRLDLA 156
|
90 100
....*....|....*....|....*....
gi 639228517 152 GIEIHQPDIILMDEPTNHLDRQSREQLYE 180
Cdd:NF000106 157 ASMIGRPAVLYLDEPTTGLDPRTRNEVWD 185
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
5-216 |
1.03e-03 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 41.69 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 5 QNITYQHPDKeilFENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEGSVYYLPQILEQ---------- 74
Cdd:PRK09700 269 RNVTSRDRKK---VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLDAvkkgmayite 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 75 -------FDTQSIARALGVQK--KLSALREILeGIVTEENitvlddnwdlEEKI-KQALETWGLLDFTADESMNRLSGGQ 144
Cdd:PRK09700 346 srrdngfFPNFSIAQNMAISRslKDGGYKGAM-GLFHEVD----------EQRTaENQRELLALKCHSVNQNITELSGGN 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 145 KTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIE---NTNKTLLVVSH---------DR-------TLLNLLPKT 205
Cdd:PRK09700 415 QQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRqlaDDGKVILMVSSelpeiitvcDRiavfcegRLTQILTNR 494
|
250
....*....|.
gi 639228517 206 AELSRKEMMLY 216
Cdd:PRK09700 495 DDMSEEEIMAW 505
|
|
| AAA_29 |
pfam13555 |
P-loop containing region of AAA domain; |
32-56 |
1.67e-03 |
|
P-loop containing region of AAA domain;
Pssm-ID: 433304 [Multi-domain] Cd Length: 61 Bit Score: 36.81 E-value: 1.67e-03
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
456-515 |
1.69e-03 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 41.15 E-value: 1.69e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639228517 456 LSGGERMRLLLAC-LSITGKAPDIIILDEPTNNLDLQNIEILTNAI---RDYKGTLLVISHD-DV 515
Cdd:TIGR00630 830 LSGGEAQRIKLAKeLSKRSTGRTLYILDEPTTGLHFDDIKKLLEVLqrlVDKGNTVVVIEHNlDV 894
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
71-200 |
2.20e-03 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 40.07 E-value: 2.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 71 ILEQFDTQSIARALGVQKKLSALREILEGIVTEENITVLD------DNWDLEEKIKQALETWGLLDFTADESMNRLSGGQ 144
Cdd:pfam13304 162 LLEDWAVLDLAADLALFPDLKELLQRLVRGLKLADLNLSDlgegieKSLLVDDRLRERGLILLENGGGGELPAFELSDGT 241
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639228517 145 KTKVLIAGI---EIHQPDIILMDEPTNHLDRQSREQLYEFIENTNKT---LLVVSHDRTLLN 200
Cdd:pfam13304 242 KRLLALLAAllsALPKGGLLLIDEPESGLHPKLLRRLLELLKELSRNgaqLILTTHSPLLLD 303
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
362-483 |
2.22e-03 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 39.02 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 362 SSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIERADFNSVYIDQDYSMINHSLSVIQQaesfnwlpLPEHEVKTILSR 441
Cdd:pfam13191 22 GRPPSVLLTGEAGTGKTTLLRELLRALERDGGYFLRGKCDENLPYSPLLEALTREGLLRQ--------LLDELESSLLEA 93
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 639228517 442 FLFGKETWDKSCSVLSGGERMRLLLACLSITGKAPD-----IIILDE 483
Cdd:pfam13191 94 WRAALLEALAPVPELPGDLAERLLDLLLRLLDLLARgerplVLVLDD 140
|
|
| VirB11-like_ATPase |
cd01130 |
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ... |
357-396 |
2.89e-03 |
|
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.
Pssm-ID: 410874 [Multi-domain] Cd Length: 177 Bit Score: 38.68 E-value: 2.89e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 639228517 357 LDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSE--GTIE 396
Cdd:cd01130 5 LRLAVRARKNILISGGTGSGKTTLLNALLSFIPPDEriVTIE 46
|
|
| VirB4_CagE |
TIGR00929 |
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found ... |
368-430 |
3.63e-03 |
|
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).
Pssm-ID: 273346 [Multi-domain] Cd Length: 785 Bit Score: 40.00 E-value: 3.63e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 368 LIIGENGSGKTTLIKLLLGQM-KPSEGTIeradfnsVYIDQDYSM------INHSLSVIQQAESFNWLPL 430
Cdd:TIGR00929 438 LIFGPTGSGKTTLLNFLLAQMqKYGGMTI-------FAFDKDRGMeifiraFGGAYLEIKDGEPFGFNPF 500
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
448-513 |
3.68e-03 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 39.16 E-value: 3.68e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 639228517 448 TWDKSCSVLSGGERMRLLLAClSITGKAPDII-ILDEPTNNLDLQN----IEILTNaIRDYKGTLLVISHD 513
Cdd:cd03270 130 TLSRSAPTLSGGEAQRIRLAT-QIGSGLTGVLyVLDEPSIGLHPRDndrlIETLKR-LRDLGNTVLVVEHD 198
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-182 |
4.11e-03 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 39.91 E-value: 4.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 1 MLTLQNITYQHPD----KEIlfENLNFIVNKGDKIAIVGNNGSGKSTLLKLISGLLT-PSAGDIRTEG------------ 63
Cdd:PRK13549 259 ILEVRNLTAWDPVnphiKRV--DDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPgRWEGEIFIDGkpvkirnpqqai 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 64 --SVYYLPqilEQFDTQSIARALGVQKK--LSALREIlegivteENITVLDDNwdLEEK-IKQALETWGLLDFTADESMN 138
Cdd:PRK13549 337 aqGIAMVP---EDRKRDGIVPVMGVGKNitLAALDRF-------TGGSRIDDA--AELKtILESIQRLKVKTASPELAIA 404
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 639228517 139 RLSGGQKTKVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFI 182
Cdd:PRK13549 405 RLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLI 448
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
333-396 |
4.13e-03 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 39.65 E-value: 4.13e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639228517 333 RGKILIKAEHINHAYQDKNIWKKpLDVVVSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE 396
Cdd:PRK15439 7 TAPPLLCARSISKQYSGVEVLKG-IDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLE 69
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
456-515 |
4.14e-03 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 40.01 E-value: 4.14e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639228517 456 LSGGERMRLLLAC-LS--ITGKApdIIILDEPTNNLDLQNIEILT---NAIRDyKG-TLLVISHD-DV 515
Cdd:COG0178 827 LSGGEAQRVKLASeLSkrSTGKT--LYILDEPTTGLHFHDIRKLLevlHRLVD-KGnTVVVIEHNlDV 891
|
|
| COG4938 |
COG4938 |
Predicted ATPase [General function prediction only]; |
367-496 |
4.94e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443965 [Multi-domain] Cd Length: 277 Bit Score: 38.80 E-value: 4.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 367 ILIIGENGSGKTTLIKLLLGqMKPSEGTI---ERADFNSVY---IDQDYSMINHSLSVIQQAESFNWLPLPEHEVKTI-- 438
Cdd:COG4938 23 TLLIGPNGSGKSTLIQALLL-LLQSNFIYlpaERSGPARLYpslVRELSDLGSRGEYTADFLAELENLEILDDKSKELle 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 439 -----LSRFLFGKETWDKS-------CSVLSGGERMRL-------------LLACLSITgKAPDIIILDEPTNNLDLQNI 493
Cdd:COG4938 102 qveewLEKIFPGKVEVDASsdlvrlvFRPSGNGKRIPLsnvgsgvsellpiLLALLSAA-KPGSLLIIEEPEAHLHPKAQ 180
|
...
gi 639228517 494 EIL 496
Cdd:COG4938 181 SAL 183
|
|
| ExeA |
COG3267 |
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ... |
357-405 |
4.94e-03 |
|
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 442498 [Multi-domain] Cd Length: 261 Bit Score: 39.00 E-value: 4.94e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 639228517 357 LDVVVSSGER-ILIIGENGSGKTTLIKLLLGQMKPsegtieraDFNSVYI 405
Cdd:COG3267 35 LEYALAQGGGfVVLTGEVGTGKTTLLRRLLERLPD--------DVKVAYI 76
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
369-522 |
5.50e-03 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 39.33 E-value: 5.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 369 IIGENGSGKTTLIKLLLGQMKPSEGTI----ERADFNSV--YIDQDYSMINHSLSVIQQAESFN--WL-------PLPEH 433
Cdd:PRK10982 29 LMGENGAGKSTLLKCLFGIYQKDSGSIlfqgKEIDFKSSkeALENGISMVHQELNLVLQRSVMDnmWLgryptkgMFVDQ 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 434 -----EVKTILSRFLFGKETWDKSCSVLSGGERMRLLLACLSITGKapdIIILDEPTNNLDLQNIEILTNAIRDYKGT-- 506
Cdd:PRK10982 109 dkmyrDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAK---IVIMDEPTSSLTEKEVNHLFTIIRKLKERgc 185
|
170 180
....*....|....*....|.
gi 639228517 507 -LLVISH--DDVF--SEEINI 522
Cdd:PRK10982 186 gIVYISHkmEEIFqlCDEITI 206
|
|
| DLIC |
pfam05783 |
Dynein light intermediate chain (DLIC); This family consists of several eukaryotic dynein ... |
350-393 |
5.88e-03 |
|
Dynein light intermediate chain (DLIC); This family consists of several eukaryotic dynein light intermediate chain proteins. The light intermediate chains (LICs) of cytoplasmic dynein consist of multiple isoforms, which undergo post-translational modification to produce a large number of species. DLIC1 is known to be involved in assembly, organization, and function of centrosomes and mitotic spindles when bound to pericentrin. DLIC2 is a subunit of cytoplasmic dynein 2 that may play a role in maintaining Golgi organization by binding cytoplasmic dynein 2 to its Golgi-associated cargo.
Pssm-ID: 368612 Cd Length: 468 Bit Score: 39.06 E-value: 5.88e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 639228517 350 KNIWKKPLDVV-------VSSGERILIIGENGSGKTTLIKLLLGQMKPSEG 393
Cdd:pfam05783 4 QNLWSSILSEVstrsrskLPSGKNVLVLGEDGSGKTTLIAKLQGVEHPKKG 54
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
135-199 |
6.44e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 39.50 E-value: 6.44e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639228517 135 ESMNRLSGGQKT------KVLIAGIEIHQPDIILMDEPTNHLDRQSREQLYEFIENTNK------TLLVVSHDRTLL 199
Cdd:PRK01156 797 EGIDSLSGGEKTavafalRVAVAQFLNNDKSLLIMDEPTAFLDEDRRTNLKDIIEYSLKdssdipQVIMISHHRELL 873
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
345-489 |
7.27e-03 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 38.28 E-value: 7.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 345 HAYQDKNIWKKPLDVVVSSGERILIIGENGSGKTTLIK-----LLLGQMKPSEG-------TIERADFNSVYIDQDYSMI 412
Cdd:PRK14267 11 RVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRtfnrlLELNEEARVEGevrlfgrNIYSPDVDPIEVRREVGMV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639228517 413 NH------SLSVIQQAE---SFNWLPLPEHEVKTILSRFLFGKETWDK-------SCSVLSGGERMRLLLAclSITGKAP 476
Cdd:PRK14267 91 FQypnpfpHLTIYDNVAigvKLNGLVKSKKELDERVEWALKKAALWDEvkdrlndYPSNLSGGQRQRLVIA--RALAMKP 168
|
170
....*....|...
gi 639228517 477 DIIILDEPTNNLD 489
Cdd:PRK14267 169 KILLMDEPTANID 181
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
361-396 |
7.56e-03 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 39.10 E-value: 7.56e-03
10 20 30
....*....|....*....|....*....|....*.
gi 639228517 361 VSSGERILIIGENGSGKTTLIKLLLGQMKPSEGTIE 396
Cdd:PRK13545 47 VPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVD 82
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
23-75 |
7.70e-03 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 39.38 E-value: 7.70e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 639228517 23 FIVNKGDKIAIVGNNGSGKSTLLKLISGLLTPSAGDIRTEG---SVYYLPQILEQF 75
Cdd:PTZ00243 1331 FRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGreiGAYGLRELRRQF 1386
|
|
| |
