|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_b-brl_3 |
pfam14905 |
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ... |
416-831 |
2.79e-88 |
|
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.
Pssm-ID: 434300 [Multi-domain] Cd Length: 407 Bit Score: 286.09 E-value: 2.79e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 416 HKFNSNGHNLSLALSVQRNRSNNYSDITETL---DSALVSHDNTERRSVTKSII----GKADYELPIGENSKLEAGYRLD 488
Cdd:pfam14905 1 HKFDKKGSELTFDADYSNYNNDSDSDYTNSDynnPGGLEPFNDSLQRNNSPSNIniytAQLDYTKPLGKKGKLEAGAKYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 489 ANKNDYNNIVNTTATNQLIPNYN--NTTDYQEVFNAFYVQFKSKVGNFGYQLGLRDELSNVKIDYSNLagsNINKTKNYN 566
Cdd:pfam14905 81 FRNNDNDYDYENLDNGEWVPDPSrsNDFDYKENIYAAYASYSKKFGKWSYQAGLRAEYTDIDGDSVTT---NETFKRNYF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 567 NLFPSIFLSYDVAKNNQILVN--YSRRIDRPRAFFMVPFPNYSNNQNIFEGNIDLNPSYVDSFEVGYSiqkKKFTVNPTL 644
Cdd:pfam14905 158 NLFPSASLSYKLNDNNSLQLSlyYRRIINRPSYWDLNPFRNYSDPYNYSQGNPNLKPEYTNSFELGYT---YKWKLSLSL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 645 YYSRTKDDNKMLVYRPDESlNVFYTKPINLGTSDRYGLDLNFTYDPLSWLKFMGSLDLFGYKTTGIAYYDAvdinknpiv 724
Cdd:pfam14905 235 SYRYTNDVIQQTFITDDND-NVTYTTYENLGKSNSYGLELSASFNPTKWWSLNGNLNGYYNKYKIDGSLNS--------- 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 725 gtmDFTGSGFStrARLNTTFKLDKTLSVQLQGQYRGAQKTASQNRSDMYSLNLGASKTIWNGDGTITFNIQDIFNTRRM- 803
Cdd:pfam14905 305 ---DFSNFGFN--WNLNNTFTLPKGWSLQLNGNYRSPRVTGQGKIKPFYSLDLGLSKSFLKKKLTLSLNVNDIFNTRKFr 379
|
410 420
....*....|....*....|....*...
gi 639234479 804 ESFTFNDDFTRRNYMQWQPRQFSISLSY 831
Cdd:pfam14905 380 STTNYDNGFIQSYNNKWDSRSVRLSLSY 407
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
129-817 |
9.69e-57 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 206.60 E-value: 9.69e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 129 IQGVTITAaaskpYKVELDKKTYDPSTDLISK-------GGTLQDVLTNVPSVAVDTDG----TVSMRG----NTNVKFL 193
Cdd:COG1629 1 LEEVVVTA-----TRTDESLQDVPGSVSVISReqledqpATDLGDLLRRVPGVSVTSAGggagQISIRGfgggGNRVLVL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 194 INGKPSSLLgiDDGANALQSIPADQIEKIEVITNPSS-KFEASGTSGILNIILKKNKKvGFNGSVTGTLGYMPRTALNAN 272
Cdd:COG1629 76 VDGVPLNDP--SGGDGGLSYIDPEDIERVEVLRGPSSaLYGSGALGGVINIVTKKPKD-GKGGEVSASYGSYGTYRASLS 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 273 LSWRKNNWTWFLNGGGGYTESKGKNETETTYNnivlpvippnqtnqpkdilshqsqnsnnktynnnynVTGGFVYDISDK 352
Cdd:COG1629 153 LSGGNGKLAYRLSASYRDSDGYRDNSDSDRYN------------------------------------LRAKLGYQLGDD 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 353 TSLSLSGVVRTFEGDNreplNTYNDFYRYDLNTHQWNFMNSLGTRTSVGRSNNLAfqgdLGLDHKFNSNGHNLSLALSVQ 432
Cdd:COG1629 197 TRLTLSASYSDSDQDS----PGYLTLAALRPRGAMDDGTNPYSNDTDDNTRDRYS----LSLEYEHLGDGLKLSASAYYR 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 433 RNRSNNYSDITETLDSALVShDNTERRSVTKSIIGKADYELPIGENSKLEAGYRLDANKNDYNNIVNTTATNQLIPNYNN 512
Cdd:COG1629 269 YDDTDLDSDFTPTPADGGTL-EQTDFDNRTYGLELRLTYDLGFGGKHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSG 347
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 513 TTDYQEVFN-AFYVQFKSKVG-NFGYQLGLRDELSNVKIDYSNLAGSNINKTKNYNNLFPSIFLSYDVAKNNQILVNYSR 590
Cdd:COG1629 348 ADDDGTTTSlALYAQDTYKLTdKLTLTAGLRYDYVSYDVDDTVTGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSR 427
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 591 RIDRPRAFFMVPFPNYSNNQnifeGNIDLNPSYVDSFEVG--YSIQKKKFTVNPTLYYSRTKDdnkMLVYRPDESLNVFY 668
Cdd:COG1629 428 GFRAPTFGELYANGTDPYSV----GNPDLKPETSTNYELGlrYRLLDGRLSLSLALFYSDVDN---EILSVPLPNDSGFS 500
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 669 TKPINLGTSDRYGLDLNFTYDPLSWLKFMGSLDLfgYKTTGIAYYDAV-DINKNPIVGTMDFTgsgfstrARLNTTFKLD 747
Cdd:COG1629 501 TYYTNAGKARSYGVELELSYQLTPGLSLNASYSY--TDAKFDDDTDGSaDLDGNRLPGVPPLT-------ANLGLTYEFP 571
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639234479 748 KTLSVQLQGQYRGAQKTASQNRSDMYS----LNLGASKTiWNGDGTITFNIQDIFNTRRMESFTFNDDFTRRNY 817
Cdd:COG1629 572 GGWSLGLGVRYVGDRYLDDANTQGAPGgytlVDLGAGYR-FGDNLTLSLGVDNLFDKKYATSLSVRASNVRGFL 644
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
163-833 |
3.63e-29 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 124.10 E-value: 3.63e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 163 TLQDVLTNVPSVAVDTDG-----TVSMRG--NTNVKFLINGKPSsLLGIDDGANALQSIPADQIEKIEVITNPSS-KFEA 234
Cdd:cd01347 17 SLADLLRRIPGVSVTRGGggggsTISIRGfgPDRTLVLVDGLPL-ASSNYGRGVDLNTIPPELIERVEVLKGPSSaLYGS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 235 SGTSGILNIILKKNKKvGFNGSVTgtLGYmprtalNANLSWRKNNWTWFLNGGGGYTEsKGKNETETTYNNivlpvipPN 314
Cdd:cd01347 96 GAIGGVVNIITKRPTD-EFGGSVT--AGY------GSDNSGSSGGGGFDVSGALADDG-AFGARLYGAYRD-------GD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 315 QTNQPKDILSHQSQNSNNktynnnynVTGGFVYDISDKTSLSLSGvvRTFEGDNREPLNTYNDFY-RYDLNTHQWNFMNS 393
Cdd:cd01347 159 GTIDGDGQADDSDEERYN--------VAGKLDWRPDDDTRLTLDA--GYQDQDADGPGGTLPANGtGSSLGGGPSSNTNG 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 394 LGTRTSVGRSNNLAFqgdLGLDHKFNSNGHNLSLALSVQRNRSNNYSDITETLDSAL---VSHDNTERRSVTKSIIGKAD 470
Cdd:cd01347 229 DRDWDYRDRYRKRAS---LGLEHDLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAggdLGRSGYSSERDTTQLGFDAG 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 471 YELPIGENS---KLEAGYRLDANKNDYNNivnttatnqlipnynnttdyqevfNAFYVQFKSKVG-NFGYQLGLRdeLSN 546
Cdd:cd01347 306 LNAPFGTGPvahTLTLGVEYRREELDEKQ------------------------TALYAQDTIELTdDLTLTLGLR--YDH 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 547 VKIDYSNLAGSNINKTKNYNNLFPSIFLSYDVAKNNQILVNYSRRIDRPRAFFMvpFPNYSNNQNIFEGNIDLNPSYVDS 626
Cdd:cd01347 360 YDQDSKDTIAGGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGEL--YGGGSHGGTAAVGNPNLKPEKSKQ 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 627 FEVGYSIQ-KKKFTVNPTLYYSRTKDdnkMLVYRPDESLNVFYTKPINLGTSDRYGLDLNFTYDPLSWLKFMGSLdlfgy 705
Cdd:cd01347 438 YELGLKYDpGDGLTLSAALFRIDIKN---EIVSTPTNTGLGLVTVYVNGGKARIRGVELEASYDLTDGLGLTGSY----- 509
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 706 kttgiAYYDAvdINKNPIVGTMDFTGSGFS-TRARLNTTFKLD-KTLSVQLQGQYRGAQK-----TASQNRSDMYSL-NL 777
Cdd:cd01347 510 -----TYTDT--EVKRTDGATTGNRLPGIPkHTANLGLDYELPdEGLTAGGGVRYRGKQYadtanGNNTVKVPGYTLvDL 582
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 639234479 778 GASKTiWNGDGTITFNIQDIFNTRRmesFTFNDDFTRRNYMQWQ-PRQFSISLSYRF 833
Cdd:cd01347 583 SASYQ-FTKNLTLRLGVNNLFDKDY---YTSLSVRGSGLYGYYGpGRTYYLSVSYKF 635
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
163-305 |
1.10e-14 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 75.29 E-value: 1.10e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 163 TLQDVLTNVPSVAVDTDG------TVSMRGNT--NVKFLINGKPSSllGIDDGANALQSIPADQIEKIEVITNPSS-KFE 233
Cdd:COG4206 34 SLADALRRVPGVQVSSSGgpgsaaSISIRGLGsnQTLVLIDGVPLN--DPSLGGVDLSLIPPDDIERIEVLKGAASaLYG 111
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639234479 234 ASGTSGILNIILKKNKKvGFNGSVTGTLGYMPRTALNANLSWRKNNWTWFLNGGGGYTESKGKNETETTYNN 305
Cdd:COG4206 112 SDAIGGVINITTKKGKK-GFKGSVSASYGSFGTRRLSASLSGGAGKFSYSLSASYRRSDGYRYNDPDLRNND 182
|
|
| CarboxypepD_reg |
pfam13620 |
Carboxypeptidase regulatory-like domain; |
36-113 |
1.68e-13 |
|
Carboxypeptidase regulatory-like domain;
Pssm-ID: 433354 [Multi-domain] Cd Length: 81 Bit Score: 66.53 E-value: 1.68e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639234479 36 VSGKITDKNGAAVPYASITFANkTNNALSDGSMTDDKGNYSL-NLTPGTYSLQVETPGFKTFQTEKTITAAGNIGSVQI 113
Cdd:pfam13620 2 ISGTVTDPSGAPVPGATVTVTN-TDTGTVRTTTTDADGRYRFpGLPPGTYTVTVSAPGFKTATRTGVTVTAGQTTTLDV 79
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
163-230 |
9.58e-09 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 53.81 E-value: 9.58e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639234479 163 TLQDVLTNVPSVAVDTDG-----TVSMRG--NTNVKFLINGKPssLLGIDDGANALQSIPADQIEKIEVITNPSS 230
Cdd:pfam07715 24 NLADALRGVPGVSVSSGGggggsSISIRGfgSNRVLVLVDGVP--LNSGGGGSVDLNSIDPEDIERVEVLKGPAS 96
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
159-833 |
1.36e-07 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 55.11 E-value: 1.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 159 SKGGTLQDVLTNVPSVAVDTDGTVSMRGNTNVK----------FLINGKPssllgiDDGANALQSIPADQIEKIEVITNP 228
Cdd:TIGR01783 17 QQAGSLSEALQRVPGVVVGGSGGTTQFGNITIRgfglevdidnVYLDGVP------LLSRGNLAIVDPAMVERVEVLRGP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 229 SSKFEA-SGTSGILNIILKKNKKVgFNGSVTGTLGYMPRTALNANLS-WRKNNWTWFLNGGGGYTESKGKNETETTYNNI 306
Cdd:TIGR01783 91 ASLLYGgSAPGGVINIVTKRPQDE-PKGSVTFGAGTRSGYRTAFDLGgPLGADGTFRGRLNGARQDGDSFYDGAGEETRL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 307 VLPVIppnqTNQPKDILSHQSQNSnnktynnnynVTGGFVYDISDKTSLSLSGVVRTFEGD---NREPLNTYNDFYRYD- 382
Cdd:TIGR01783 170 GATAT----DWQLDDRTLLRLGAY----------YQKERDRGGYGGLPASGGTSGRDLSSDrylGTSSNRNYDDREYLSy 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 383 LNTHQWNFMNSLgTRTSVGRSNNLAFQGDLGLDHKFNSNGHNLSLALSVQRNRSNNYSdITETLDSALVSHDNTERRSVt 462
Cdd:TIGR01783 236 GLSLEYQFNDVW-TGKQNLRYSYFDTDSNQVQASGYSSDGGLFGRSLTVVNVKQDRVQ-IDAGLDGEFETGPIEHDLLL- 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 463 ksiiGKADYELpigENSKLEAGYRLDANKNDYNNIVNTTATNQLIPNYNNTTDYQEVFNAFYVQFKSKVGNFGYQLGLRD 542
Cdd:TIGR01783 313 ----GVSYGQR---TTNRFNNTGYPSDNIYSLTATSSARTDIGDSPKDRALSSTTKALNGVALQRILLADKWTLTLGGRY 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 543 ElsnvKIDYSNLAGSNIN-KTKNYNNLFPSIFLSYDVAKNNQILVNYSRRIDRPRAFFmvpfPNYSNNQNIFEgnidlnP 621
Cdd:TIGR01783 386 D----SVDVKSNNGVAGStGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYP----KGAGNSGDILE------P 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 622 SYVDSFEVGYSIQK-KKFTVNPTLYysRTKDDNKMLVYRPDeslNVFYtkpINLGTSDRYGLDLNFTYDPLswlkfmGSL 700
Cdd:TIGR01783 452 EKGKNYELGVRYDLgDSLLATAALF--RITKDNQLVQDPVN---GTFS---VNAGKTRNRGVELEARGYLT------PGL 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 701 DLFGykttGIAYYDAvDINKNPIVGTMDFTGSGFS-TRARLNTTFKL---DKTLSVQLQGQYRGAQKTASQNRSDMYS-- 774
Cdd:TIGR01783 518 SLSA----GYTYTDA-EFTEDTNGDTQGNTVPFVPkHTASLWASYAPpvgDNGLTLGGGVQYTGKAYVDGGNTGKVPSyt 592
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639234479 775 -LNLGASKTI-WNGDGTITFNIQDIFNTRRmesFTFNDDFTRRNYMQW-QPRQFSISLSYRF 833
Cdd:TIGR01783 593 vVDLSVRYDLtKKKNLTLALNVNNLFDRDY---YTSGYRWGPSAYIYPgAPRTVGLSVSYDF 651
|
|
| PRK10064 |
PRK10064 |
catecholate siderophore receptor CirA; Provisional |
115-258 |
4.73e-07 |
|
catecholate siderophore receptor CirA; Provisional
Pssm-ID: 236646 [Multi-domain] Cd Length: 663 Bit Score: 53.74 E-value: 4.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 115 ALKGQEAVDSKTQSIQGVTITAAAskpykVELDKKTYDPSTDLISKGG-------TLQDVLTNVPSVAVDTDGT----VS 183
Cdd:PRK10064 16 AISCAWPVLAVDDDGETMVVTASA-----VEQNLKDAPASISVITQEDlqrkpvqNLKDVLKEVPGVQLTNEGDnrkgVS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 184 MRG--NTNVKFLINGKPSsllgidDGANA--------LQSIPADQIEKIEVITNP-SSKFEASGTSGILNIIlkkNKKVG 252
Cdd:PRK10064 91 IRGldSSYTLILIDGKRV------NSRNAvfrhndfdLNWIPVDAIERIEVVRGPmSSLYGSDALGGVVNII---TKKIG 161
|
....*...
gi 639234479 253 --FNGSVT 258
Cdd:PRK10064 162 qkWHGTVT 169
|
|
| Peptidase_M14NE-CP-C_like |
cd11308 |
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, ... |
36-113 |
1.17e-03 |
|
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; This domain is found C-terminal to the M14 carboxypeptidase (CP) N/E subfamily containing zinc-binding enzymes that hydrolyze single C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. The N/E subfamily includes enzymatically active members (carboxypeptidase N, E, M, D, and Z), as well as non-active members (carboxypeptidase-like protein 1, -2, aortic CP-like protein, and adipocyte enhancer binding protein-1) which lack the critical active site and substrate-binding residues considered necessary for activity. The active N/E enzymes fulfill a variety of cellular functions, including prohormone processing, regulation of peptide hormone activity, alteration of protein-protein or protein-cell interactions and transcriptional regulation. For M14 CPs, it has been suggested that this domain may assist in folding of the CP domain, regulate enzyme activity, or be involved in interactions with other proteins or with membranes; for carboxypeptidase M, it may interact with the bradykinin 1 receptor at the cell surface. This domain may also be found in other peptidase families.
Pssm-ID: 200604 [Multi-domain] Cd Length: 76 Bit Score: 38.27 E-value: 1.17e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639234479 36 VSGKITDKNGAAVPYASITFANKTNNAlsdgsMTDDKGNYSLNLTPGTYSLQVETPGFKtfQTEKTITAAGNIGSVQI 113
Cdd:cd11308 2 IKGFVTDATGNPIANATISVEGINHDV-----TTAKDGDYWRLLLPGTYNVTASAPGYQ--PVTKTVTVPNNFSATVV 72
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_b-brl_3 |
pfam14905 |
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ... |
416-831 |
2.79e-88 |
|
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.
Pssm-ID: 434300 [Multi-domain] Cd Length: 407 Bit Score: 286.09 E-value: 2.79e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 416 HKFNSNGHNLSLALSVQRNRSNNYSDITETL---DSALVSHDNTERRSVTKSII----GKADYELPIGENSKLEAGYRLD 488
Cdd:pfam14905 1 HKFDKKGSELTFDADYSNYNNDSDSDYTNSDynnPGGLEPFNDSLQRNNSPSNIniytAQLDYTKPLGKKGKLEAGAKYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 489 ANKNDYNNIVNTTATNQLIPNYN--NTTDYQEVFNAFYVQFKSKVGNFGYQLGLRDELSNVKIDYSNLagsNINKTKNYN 566
Cdd:pfam14905 81 FRNNDNDYDYENLDNGEWVPDPSrsNDFDYKENIYAAYASYSKKFGKWSYQAGLRAEYTDIDGDSVTT---NETFKRNYF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 567 NLFPSIFLSYDVAKNNQILVN--YSRRIDRPRAFFMVPFPNYSNNQNIFEGNIDLNPSYVDSFEVGYSiqkKKFTVNPTL 644
Cdd:pfam14905 158 NLFPSASLSYKLNDNNSLQLSlyYRRIINRPSYWDLNPFRNYSDPYNYSQGNPNLKPEYTNSFELGYT---YKWKLSLSL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 645 YYSRTKDDNKMLVYRPDESlNVFYTKPINLGTSDRYGLDLNFTYDPLSWLKFMGSLDLFGYKTTGIAYYDAvdinknpiv 724
Cdd:pfam14905 235 SYRYTNDVIQQTFITDDND-NVTYTTYENLGKSNSYGLELSASFNPTKWWSLNGNLNGYYNKYKIDGSLNS--------- 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 725 gtmDFTGSGFStrARLNTTFKLDKTLSVQLQGQYRGAQKTASQNRSDMYSLNLGASKTIWNGDGTITFNIQDIFNTRRM- 803
Cdd:pfam14905 305 ---DFSNFGFN--WNLNNTFTLPKGWSLQLNGNYRSPRVTGQGKIKPFYSLDLGLSKSFLKKKLTLSLNVNDIFNTRKFr 379
|
410 420
....*....|....*....|....*...
gi 639234479 804 ESFTFNDDFTRRNYMQWQPRQFSISLSY 831
Cdd:pfam14905 380 STTNYDNGFIQSYNNKWDSRSVRLSLSY 407
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
129-817 |
9.69e-57 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 206.60 E-value: 9.69e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 129 IQGVTITAaaskpYKVELDKKTYDPSTDLISK-------GGTLQDVLTNVPSVAVDTDG----TVSMRG----NTNVKFL 193
Cdd:COG1629 1 LEEVVVTA-----TRTDESLQDVPGSVSVISReqledqpATDLGDLLRRVPGVSVTSAGggagQISIRGfgggGNRVLVL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 194 INGKPSSLLgiDDGANALQSIPADQIEKIEVITNPSS-KFEASGTSGILNIILKKNKKvGFNGSVTGTLGYMPRTALNAN 272
Cdd:COG1629 76 VDGVPLNDP--SGGDGGLSYIDPEDIERVEVLRGPSSaLYGSGALGGVINIVTKKPKD-GKGGEVSASYGSYGTYRASLS 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 273 LSWRKNNWTWFLNGGGGYTESKGKNETETTYNnivlpvippnqtnqpkdilshqsqnsnnktynnnynVTGGFVYDISDK 352
Cdd:COG1629 153 LSGGNGKLAYRLSASYRDSDGYRDNSDSDRYN------------------------------------LRAKLGYQLGDD 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 353 TSLSLSGVVRTFEGDNreplNTYNDFYRYDLNTHQWNFMNSLGTRTSVGRSNNLAfqgdLGLDHKFNSNGHNLSLALSVQ 432
Cdd:COG1629 197 TRLTLSASYSDSDQDS----PGYLTLAALRPRGAMDDGTNPYSNDTDDNTRDRYS----LSLEYEHLGDGLKLSASAYYR 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 433 RNRSNNYSDITETLDSALVShDNTERRSVTKSIIGKADYELPIGENSKLEAGYRLDANKNDYNNIVNTTATNQLIPNYNN 512
Cdd:COG1629 269 YDDTDLDSDFTPTPADGGTL-EQTDFDNRTYGLELRLTYDLGFGGKHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSG 347
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 513 TTDYQEVFN-AFYVQFKSKVG-NFGYQLGLRDELSNVKIDYSNLAGSNINKTKNYNNLFPSIFLSYDVAKNNQILVNYSR 590
Cdd:COG1629 348 ADDDGTTTSlALYAQDTYKLTdKLTLTAGLRYDYVSYDVDDTVTGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSR 427
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 591 RIDRPRAFFMVPFPNYSNNQnifeGNIDLNPSYVDSFEVG--YSIQKKKFTVNPTLYYSRTKDdnkMLVYRPDESLNVFY 668
Cdd:COG1629 428 GFRAPTFGELYANGTDPYSV----GNPDLKPETSTNYELGlrYRLLDGRLSLSLALFYSDVDN---EILSVPLPNDSGFS 500
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 669 TKPINLGTSDRYGLDLNFTYDPLSWLKFMGSLDLfgYKTTGIAYYDAV-DINKNPIVGTMDFTgsgfstrARLNTTFKLD 747
Cdd:COG1629 501 TYYTNAGKARSYGVELELSYQLTPGLSLNASYSY--TDAKFDDDTDGSaDLDGNRLPGVPPLT-------ANLGLTYEFP 571
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639234479 748 KTLSVQLQGQYRGAQKTASQNRSDMYS----LNLGASKTiWNGDGTITFNIQDIFNTRRMESFTFNDDFTRRNY 817
Cdd:COG1629 572 GGWSLGLGVRYVGDRYLDDANTQGAPGgytlVDLGAGYR-FGDNLTLSLGVDNLFDKKYATSLSVRASNVRGFL 644
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
115-786 |
1.13e-42 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 165.03 E-value: 1.13e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 115 ALKGQEAVDSKTQSIQGVTITAAASKPYKVELDKKTYDPSTDLISKGG--TLQDVLTNVPSVAVDTDG------TVSMRG 186
Cdd:COG4771 13 AAQAADALAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGatDLADALRLLPGVSVTRSGgrggssGISIRG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 187 --NTNVKFLINGKPSSLlGIDDGANALQSIPADQIEKIEVITNP-SSKFEASGTSGILNIILKKNKKvGFNGSVTGTLGY 263
Cdd:COG4771 93 lgGDRVLVLIDGVPVNN-PALGGGGDLSYIPPDDIERIEVIRGPaSALYGSDAIGGVINIITKKPTD-ELEGSVSLGYGS 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 264 MPRTALNANLSWRKNNWTWFLNGGGGYTESKGknetetTYNNIVLPVIPPNQTNQpkdilshqsqnsnnktynnnYNVTG 343
Cdd:COG4771 171 NGNGTYSGSLSLGGPGDKLSFLLSGSYRDRDG------YLDYRNGGFVGNSGYER--------------------YNLNA 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 344 GFVYDISDKTSLSLSGvvrtfegdnreplntynDFYRYDLNTHQWNFMNSLGTRTSVGRSNNLAFQGDLGLDHKFNsNGH 423
Cdd:COG4771 225 KLGYRLSDNHRLSLSG-----------------GYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGNYSLRYNGD-LGD 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 424 NLSLALSVQRNRSNNYSDITETLDSALVSHDNTErrsvtksIIGKADYELPIGENSKLEAGyrLDANKNDYNNivnttat 503
Cdd:COG4771 287 NLDLSLYYSRTDRDSTNGSLGGSTGSFSDSDDTT-------YGLELDLTYPLGGNHTLTLG--AEYRYDDLDS------- 350
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 504 nqliPNYNNTTDYQEVFNAFYVQFKSKVG-NFGYQLGLRdelsnvkIDYSNLAGSNinktkNYNNLFPSIFLSYDVAKNN 582
Cdd:COG4771 351 ----SSFLGGADASRDTYGLFAQDEWKLTdKLTLTAGLR-------YDYYSTFGAS-----NYTAFSPRLGLRYDLSDNL 414
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 583 QILVNYSRRIDRPRAFFMVPFPNYSNNQNIFeGNIDLNPSYVDSFEVG--YSIQKKKFTVNPTLYYSRTKDdnkMLVYRP 660
Cdd:COG4771 415 TLRASYGRGFRAPSLAELYGSGTGTPGRYVL-GNPDLKPETSDNYELGleYRLGNGGLSLSLTGFYTDIKD---LIVLVP 490
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 661 DESLNVFYTKPINLGTSDRYGLDLNFTYDPLSWLKFMGSLdlfgykttgiAYYDAvDINKNPIVGTMDFTgsgFSTRARL 740
Cdd:COG4771 491 VGPGPGDVLQYENVGKARTYGLELELKYRLGKGLTLTASY----------TYLDS-KIDDGDTGEPLPNV---PPHKANL 556
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 639234479 741 NTTFKLDKTLSVQLQGQYRGAQKTASQNRSD------MYSLNLGASKTIWNG 786
Cdd:COG4771 557 GLDYRLPKWWLLLLLTRYYGGRYVTPPSGRLegytpgYTLLDLRASYKLTKN 608
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
163-833 |
3.63e-29 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 124.10 E-value: 3.63e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 163 TLQDVLTNVPSVAVDTDG-----TVSMRG--NTNVKFLINGKPSsLLGIDDGANALQSIPADQIEKIEVITNPSS-KFEA 234
Cdd:cd01347 17 SLADLLRRIPGVSVTRGGggggsTISIRGfgPDRTLVLVDGLPL-ASSNYGRGVDLNTIPPELIERVEVLKGPSSaLYGS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 235 SGTSGILNIILKKNKKvGFNGSVTgtLGYmprtalNANLSWRKNNWTWFLNGGGGYTEsKGKNETETTYNNivlpvipPN 314
Cdd:cd01347 96 GAIGGVVNIITKRPTD-EFGGSVT--AGY------GSDNSGSSGGGGFDVSGALADDG-AFGARLYGAYRD-------GD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 315 QTNQPKDILSHQSQNSNNktynnnynVTGGFVYDISDKTSLSLSGvvRTFEGDNREPLNTYNDFY-RYDLNTHQWNFMNS 393
Cdd:cd01347 159 GTIDGDGQADDSDEERYN--------VAGKLDWRPDDDTRLTLDA--GYQDQDADGPGGTLPANGtGSSLGGGPSSNTNG 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 394 LGTRTSVGRSNNLAFqgdLGLDHKFNSNGHNLSLALSVQRNRSNNYSDITETLDSAL---VSHDNTERRSVTKSIIGKAD 470
Cdd:cd01347 229 DRDWDYRDRYRKRAS---LGLEHDLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAggdLGRSGYSSERDTTQLGFDAG 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 471 YELPIGENS---KLEAGYRLDANKNDYNNivnttatnqlipnynnttdyqevfNAFYVQFKSKVG-NFGYQLGLRdeLSN 546
Cdd:cd01347 306 LNAPFGTGPvahTLTLGVEYRREELDEKQ------------------------TALYAQDTIELTdDLTLTLGLR--YDH 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 547 VKIDYSNLAGSNINKTKNYNNLFPSIFLSYDVAKNNQILVNYSRRIDRPRAFFMvpFPNYSNNQNIFEGNIDLNPSYVDS 626
Cdd:cd01347 360 YDQDSKDTIAGGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGEL--YGGGSHGGTAAVGNPNLKPEKSKQ 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 627 FEVGYSIQ-KKKFTVNPTLYYSRTKDdnkMLVYRPDESLNVFYTKPINLGTSDRYGLDLNFTYDPLSWLKFMGSLdlfgy 705
Cdd:cd01347 438 YELGLKYDpGDGLTLSAALFRIDIKN---EIVSTPTNTGLGLVTVYVNGGKARIRGVELEASYDLTDGLGLTGSY----- 509
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 706 kttgiAYYDAvdINKNPIVGTMDFTGSGFS-TRARLNTTFKLD-KTLSVQLQGQYRGAQK-----TASQNRSDMYSL-NL 777
Cdd:cd01347 510 -----TYTDT--EVKRTDGATTGNRLPGIPkHTANLGLDYELPdEGLTAGGGVRYRGKQYadtanGNNTVKVPGYTLvDL 582
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 639234479 778 GASKTiWNGDGTITFNIQDIFNTRRmesFTFNDDFTRRNYMQWQ-PRQFSISLSYRF 833
Cdd:cd01347 583 SASYQ-FTKNLTLRLGVNNLFDKDY---YTSLSVRGSGLYGYYGpGRTYYLSVSYKF 635
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
362-832 |
7.06e-25 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 109.09 E-value: 7.06e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 362 RTFEGDNREPLNTYNDFYRYDLNTHQWNFMNSLGTRTSVGRSNNLAFQGDLGLDHKFNSNGH-NLSLALSVQRNRSNNYS 440
Cdd:pfam00593 15 LTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSwLSTLRLGLRYSSLDGDY 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 441 DITETLDSALVSHDNTERRSVTKSIIGKADYELPIgeNSKLEAGYRLDANKNDYNNI--VNTTATNQLIPNYNNTTDYQE 518
Cdd:pfam00593 95 TSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDL--SHDLLLGVELRTAGLDYRRLddDAYDPYDPANPSSSSYSDTTT 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 519 VFNAFYVQFKSKV-GNFGYQLGLRdeLSNVKIDYSNLAGSNINKTKNYNNLFPSIFLSYDVAKNNQILVNYSRRIDRPRA 597
Cdd:pfam00593 173 DSYGLYLQDNIKLtDRLTLTLGLR--YDHYSTDGDDGNGGGDNFSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 598 FFMVPFPNYSNNQNIFEGNIDLNPSYVDSFEVGYSIQKKKFTVNPTLYYSRTKDdnkMLVYRPD-ESLNVFYTKPINLGT 676
Cdd:pfam00593 251 GELYGSGSGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKN---LITSDPDgPGLGGTVYTYTNVGK 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 677 SDRYGLDLNFTYDPLSwlkFMGSLDLFGYKTTGIAYydAVDINKNPIVGTMDFTGSGFSTRARLNTTFKLDKTLSVQLQG 756
Cdd:pfam00593 328 ARIRGVELELSGRLWG---LGLSGGGYTYTDADDDA--DADDTGNPLPNVPRHTANLGLTYDFPLGGWGARLGARYVGSG 402
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639234479 757 QYRGAQKTASQNRSDMYSLNLGASKTIwNGDGTITFNIQDIFNTRRMESFTFNDDFTRRNYMqwQPRQFSISLSYR 832
Cdd:pfam00593 403 ERRYGDAANTFKTPGYTLVDLSAGYRL-NKNLTLRLGVNNLFDKYYKRYYSSGGGNLGGYPG--PGRTFYLGLSYK 475
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
115-833 |
1.25e-18 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 90.76 E-value: 1.25e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 115 ALKGQEAVDSKTQSIQGVTITAAASKPYKVELDKKtydpSTDLISK-------GGTLQDVLTNVPSV-AVDTDGT----- 181
Cdd:COG4772 9 LLLAAAAAAEAATTLETVVVTGSRAAEARLKDVPG----SVSVVDReelenqaATSLREVLRRVPGVnVQEEDGFglrpn 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 182 VSMRGNT-----NVKFLINGKPSSLLGIDDGANALQSiPADQIEKIEVITNPSS-KFEASGTSGILNIILKK-NKKVGFN 254
Cdd:COG4772 85 IGIRGLGprrsrGITLLEDGIPIAPAPYGDPAAYYFP-DLERMERIEVLRGAAAlRYGPQTVGGAINFVTRTiPTAFGGE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 255 GSVTGTlGYMPRTAlNANLSWRKNNWTWFLNG----GGGYteskgKNETETTYNNIVLpvippnqtnqpkdilshqsqns 330
Cdd:COG4772 164 LRVTGG-SFGYRRT-HASVGGTVGNFGYLVEYsrkrGDGF-----RDNSGFDINDFNA---------------------- 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 331 nnktynnnynvtgGFVYDISDKTSLSLSgvVRTFEGDNREPLN-TYNDF----YRydlNTHQWNFMNslGTRTsvgrsnn 405
Cdd:COG4772 215 -------------KLGYRLSDRQELTLK--FQYYDEDANTPGGlTDAQFdadpRQ---SYRPADQFD--TRRT------- 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 406 lafQGDLGLDHKFNSNgHNLSL---ALSVQRNRSNNYSDITETLDSALVSHDNTERRSVTKSIIGKADYELpIGENSKLE 482
Cdd:COG4772 268 ---QLSLRYEHQLSDN-TTLTTtayYNDFSRNWYIRQNTADPNTPGLGLRGNPRGYRSYGIEPRLTHRFEL-GGVPHTLE 342
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 483 AGYRLDANKNDYNNIVNTTAT----NQLIPNYNNTTDYqevfNAFYVQFKSKV-GNFGYQLGLRDEL--SNVKIDYSNLA 555
Cdd:COG4772 343 VGLRYHREEEDRKQYVNTYGQgrsgAGLRRDRRFSADA----LAAYAQNRFELtGRLTLTPGLRYEHirRDRTDRYSTRT 418
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 556 GSNINKTKNYNNLFPSIFLSYDVAKNNQILVNYSRRIdRPraffmvpfPNYSNNQNIFEGNIDLNPSYVDSFEVG--YSI 633
Cdd:COG4772 419 GGDDSGSNSYSEFLPGLGLLYQLTDNLQLYANVSRGF-EP--------PTFGDLAYGNGGNPDLKPEKSWNYELGtrGRI 489
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 634 qKKKFTVNPTLYYSRTkdDNKMLVYRPDESLNVFYTkpiNLGTSDRYGLDLNFTYDPlsWLKFMGSLDLFgyktTGIAYY 713
Cdd:COG4772 490 -GNGLSAEVALFYIDY--DNELGSCSAAGGDRSTFT---NAGETRHQGLELALDYDL--LKGGGLGLPLF----AAYTYT 557
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 714 DA-------VDINKNPIVGTMDFTgsgFSTRARLNTtfkldKTLSVQLQGQYRGAQKTASQNRSDMYS---------LNL 777
Cdd:COG4772 558 DAeftsdfgPVFAGNRLPYVPRHQ---LTAGLGYEH-----GGWTANLNGRYVSEQFTDAANTVADGSfgkipsytvLDL 629
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 639234479 778 GASKTiWNGDGTITFNIQDIFNTRrmeSFTFNDDFTRRNYMQWQPRQFSISLSYRF 833
Cdd:COG4772 630 SASYD-FGKNLSLFAGVNNLFDKR---YIASRAPNYAAGIRPGPPRTVYAGLRLKF 681
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
163-833 |
2.26e-15 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 80.31 E-value: 2.26e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 163 TLQDVLTNVPSVAVDTDG-----TVSMRG-NTNVKFLINGkpssllgIDDGANalQSIPADQIEKIEVITNPSSK-FEAS 235
Cdd:COG4774 28 SLADALRNVPGVTFGAGEggngdSFSIRGfSASGDIYVDG-------LRDPGQ--YRRDTFNLERVEVLKGPASVlYGRG 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 236 GTSGILNIILKKNKKVGFNgSVTGTLG----YMPR----TALNANLSWRknnwtwfLNGGGgyteskgkNETETTYNNIv 307
Cdd:COG4774 99 SPGGVINLVTKRPTDEPFT-EVTLTYGsdgqRRATldvnGPLGDDLAYR-------LNGMY--------RDSDSYRDGV- 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 308 lpvippnqtnqpkdilshqsqnsnnktYNNNYNVTGGFVYDISDKTSLSLSGvvrtfegdnreplntynDFYRYDLNTHQ 387
Cdd:COG4774 162 ---------------------------DNDRWGIAPSLTWRLGDRTRLTLDY-----------------EYQDDDRTPDY 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 388 WNFMNSLGTRTSVGRSNNLAFQGD----------LGLDHKFNSNgHNLSLALSVQR-NRSNNYSDITETLDSALVSHDNT 456
Cdd:COG4774 198 GVPAVANGRPVDVDRSTFYGQPDDysdsetdsatLRLEHDFNDN-WTLRNALRYSDyDRDYRNTYPTGGNATGTVTRSAY 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 457 ERRSVTKSIIGKAD--YELPIGE-NSKLEAG---YRLDANKNDYNNIVNTTATNQLIPNYNNTTDYQEVFNAFYvqfKSK 530
Cdd:COG4774 277 RRDQDNDTLSNQTDltGKFDTGGvKHTLLAGveySREDSDNARYSGGGTAPTVNLYNPVYGAPVTGPTLGGADN---DSR 353
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 531 VGNFGY----QLGLRDELS--------NVKIDYSNLAGSNINKTKNYNNLFPSIFLSYDVAKNNQILVNYSRridrprAF 598
Cdd:COG4774 354 TDTTGLylqdTISLTDRWSllaglrydRFDTDYTDRTTGATTSSYDDSAFSPRAGLVYKPTPNLSLYASYST------SF 427
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 599 FMVP-FPNYSNNQNIFEgnidlnPSYVDSFEVG--YSIQKKKFTVNPTLYYSRTKDdnkmlVYRPDESLNVFYtkpINLG 675
Cdd:COG4774 428 NPGGgAPSLSNAGQALD------PEKSRQYEVGvkWDLLDGRLSLTAALFRIEKTN-----VRTTDPANPGVY---VQTG 493
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 676 TSDRYGLDLNFTYDPLSWLKFMGsldlfgykttGIAYYDA-------VDINKNPIVGTMDFTGSGFSTRarlntTFKLDK 748
Cdd:COG4774 494 EQRSRGVELEATGELTPGWSVLA----------GYTYLDAeitksanAANVGNRLPNVPRHSASLWTTY-----DLPLPG 558
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 749 tLSVQLQGQYRGAQKTASQNRSDM---YSLNLGASKTIwNGDGTITFNIQDIFNTRRMESFTFNDdftrrNYMQWQPRQF 825
Cdd:COG4774 559 -LTLGGGVRYVGSRYADAANTVKLpsyTRFDAGASYRL-NKNLTLRLNVNNLTDKRYYASAYGSG-----YVTPGAPRTV 631
|
....*...
gi 639234479 826 SISLSYRF 833
Cdd:COG4774 632 LLSASYRF 639
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
163-305 |
1.10e-14 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 75.29 E-value: 1.10e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 163 TLQDVLTNVPSVAVDTDG------TVSMRGNT--NVKFLINGKPSSllGIDDGANALQSIPADQIEKIEVITNPSS-KFE 233
Cdd:COG4206 34 SLADALRRVPGVQVSSSGgpgsaaSISIRGLGsnQTLVLIDGVPLN--DPSLGGVDLSLIPPDDIERIEVLKGAASaLYG 111
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639234479 234 ASGTSGILNIILKKNKKvGFNGSVTGTLGYMPRTALNANLSWRKNNWTWFLNGGGGYTESKGKNETETTYNN 305
Cdd:COG4206 112 SDAIGGVINITTKKGKK-GFKGSVSASYGSFGTRRLSASLSGGAGKFSYSLSASYRRSDGYRYNDPDLRNND 182
|
|
| CarboxypepD_reg |
pfam13620 |
Carboxypeptidase regulatory-like domain; |
36-113 |
1.68e-13 |
|
Carboxypeptidase regulatory-like domain;
Pssm-ID: 433354 [Multi-domain] Cd Length: 81 Bit Score: 66.53 E-value: 1.68e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639234479 36 VSGKITDKNGAAVPYASITFANkTNNALSDGSMTDDKGNYSL-NLTPGTYSLQVETPGFKTFQTEKTITAAGNIGSVQI 113
Cdd:pfam13620 2 ISGTVTDPSGAPVPGATVTVTN-TDTGTVRTTTTDADGRYRFpGLPPGTYTVTVSAPGFKTATRTGVTVTAGQTTTLDV 79
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
163-833 |
8.34e-12 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 68.77 E-value: 8.34e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 163 TLQDVLTNVPSVAVDTDGT-----VSMRGNTNVKFLINGKPSsllgiddGANALQSIPADQIEKIEVITNPSSKFEASGT 237
Cdd:COG4773 84 TLDDALRNVPGVTVSSYDGggrdsFSIRGFSIDNYLRDGLPL-------GGFGGGQPDTANLERVEVLKGPAGLLYGAGS 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 238 -SGILNIILKKNKKVgFNGSVTGTLG----YmpRTA------LNANLSWRknnwtWFLNGGGGYTESkgknETETTYNNI 306
Cdd:COG4773 157 pGGLVNLVTKRPTAE-PQGEVSLSAGswdtY--RATadvggpLNEDGTLR-----YRLNAAYEDGDS----FRDGVDNRR 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 307 VLpvippnqtnqpkdilshqsqnsnnktynnnynVTGGFVYDISDKTSLSLSGVvrtfegdnreplntyndfYRYDLNTH 386
Cdd:COG4773 225 TL--------------------------------IAPSLDWDLTDDTTLTLGAE------------------YQDDDSTG 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 387 QWNFMNSLGTRTSVGRSNNLAFQGD----------LGLDHKFNSNGhNLSLALSVQRNRSNN---YSDITETLDSALVSH 453
Cdd:COG4773 255 DRGFLPLDGTLLDLPRSTNLGEPWDyydtetttlfAELEHRFNDDW-SLRANARYSDSDRDGrsaYAYGAPDAATGTLTR 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 454 DNTERRSVTKSIIGKADYELPI--------------GENSKLEAGYRLDANKNDYNNIVNTTATNQLIPNYNNTTDYQev 519
Cdd:COG4773 334 YASARDGDSRSDSLDANLNGKFetgglehtllvgadYSRYDSDSDSATAGTINIYNPVYGNLPEPDFDASDTDTTTRQ-- 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 520 fNAFYVQ--FkskvgNFGYQL----GLRdeLSNVKIDYSNLAGSNiNKTKNYNNLFPSIFLSYDVAKNNQILVNYSrrid 593
Cdd:COG4773 412 -TGLYAQdqI-----SLTDRLslllGGR--YDWYETDSTNRLGGS-TTSYDDSAFTPRAGLVYDLTPGLSLYASYS---- 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 594 rpRAFfmVPFPNYSNNQNIFEgnidlnPSYVDSFEVG--YSIQKKKFTVNPTLYysRTKDDNkmlVYRPDESLNVFYtkp 671
Cdd:COG4773 479 --ESF--EPQSGADNNGNPLD------PETGKQYEAGvkGELFDGRLNATLAVF--DITQKN---VATTDPDNPNFY--- 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 672 INLGTSDRYGLDLNFTYDPLSWLKFMGsldlfgykttGIAYYDA------VDINKNPIVGTMDFTGSGFSTRarlNTTFK 745
Cdd:COG4773 541 VQVGEVRSRGVELELSGELTPGLNLIA----------GYTYTDAkitkdaDALEGKRLTNVPRHTASLWTTY---RFPSG 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 746 LDKTLSVQLQGQYRGAQKTASQNRSDM--YSL-NLGASKTiWNGDGTITFNIQDIFNTRRMESFTFNDdftrRNYMQwQP 822
Cdd:COG4773 608 ALKGLGLGGGVRYVGERYGDAANTFTLpsYTLvDAGARYD-LGKNWTLQLNVNNLFDKKYYASSGSRG----YVYYG-AP 681
|
730
....*....|.
gi 639234479 823 RQFSISLSYRF 833
Cdd:COG4773 682 RNVRLSLSYKF 692
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
163-230 |
9.58e-09 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 53.81 E-value: 9.58e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639234479 163 TLQDVLTNVPSVAVDTDG-----TVSMRG--NTNVKFLINGKPssLLGIDDGANALQSIPADQIEKIEVITNPSS 230
Cdd:pfam07715 24 NLADALRGVPGVSVSSGGggggsSISIRGfgSNRVLVLVDGVP--LNSGGGGSVDLNSIDPEDIERVEVLKGPAS 96
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
36-107 |
6.58e-08 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 50.67 E-value: 6.58e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639234479 36 VSGKITDKN-GAAVPYASITFANKTNnalsdGSMTDDKGNYSL-NLTPGTYSLQVETPGFKTFqtEKTITAAGN 107
Cdd:pfam13715 1 ISGTVVDENtGEPLPGATVYVKGTTK-----GTVTDADGNFELkNLPAGTYTLVVSFVGYKTQ--EKKVTVSND 67
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
159-833 |
1.36e-07 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 55.11 E-value: 1.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 159 SKGGTLQDVLTNVPSVAVDTDGTVSMRGNTNVK----------FLINGKPssllgiDDGANALQSIPADQIEKIEVITNP 228
Cdd:TIGR01783 17 QQAGSLSEALQRVPGVVVGGSGGTTQFGNITIRgfglevdidnVYLDGVP------LLSRGNLAIVDPAMVERVEVLRGP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 229 SSKFEA-SGTSGILNIILKKNKKVgFNGSVTGTLGYMPRTALNANLS-WRKNNWTWFLNGGGGYTESKGKNETETTYNNI 306
Cdd:TIGR01783 91 ASLLYGgSAPGGVINIVTKRPQDE-PKGSVTFGAGTRSGYRTAFDLGgPLGADGTFRGRLNGARQDGDSFYDGAGEETRL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 307 VLPVIppnqTNQPKDILSHQSQNSnnktynnnynVTGGFVYDISDKTSLSLSGVVRTFEGD---NREPLNTYNDFYRYD- 382
Cdd:TIGR01783 170 GATAT----DWQLDDRTLLRLGAY----------YQKERDRGGYGGLPASGGTSGRDLSSDrylGTSSNRNYDDREYLSy 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 383 LNTHQWNFMNSLgTRTSVGRSNNLAFQGDLGLDHKFNSNGHNLSLALSVQRNRSNNYSdITETLDSALVSHDNTERRSVt 462
Cdd:TIGR01783 236 GLSLEYQFNDVW-TGKQNLRYSYFDTDSNQVQASGYSSDGGLFGRSLTVVNVKQDRVQ-IDAGLDGEFETGPIEHDLLL- 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 463 ksiiGKADYELpigENSKLEAGYRLDANKNDYNNIVNTTATNQLIPNYNNTTDYQEVFNAFYVQFKSKVGNFGYQLGLRD 542
Cdd:TIGR01783 313 ----GVSYGQR---TTNRFNNTGYPSDNIYSLTATSSARTDIGDSPKDRALSSTTKALNGVALQRILLADKWTLTLGGRY 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 543 ElsnvKIDYSNLAGSNIN-KTKNYNNLFPSIFLSYDVAKNNQILVNYSRRIDRPRAFFmvpfPNYSNNQNIFEgnidlnP 621
Cdd:TIGR01783 386 D----SVDVKSNNGVAGStGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYP----KGAGNSGDILE------P 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 622 SYVDSFEVGYSIQK-KKFTVNPTLYysRTKDDNKMLVYRPDeslNVFYtkpINLGTSDRYGLDLNFTYDPLswlkfmGSL 700
Cdd:TIGR01783 452 EKGKNYELGVRYDLgDSLLATAALF--RITKDNQLVQDPVN---GTFS---VNAGKTRNRGVELEARGYLT------PGL 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 701 DLFGykttGIAYYDAvDINKNPIVGTMDFTGSGFS-TRARLNTTFKL---DKTLSVQLQGQYRGAQKTASQNRSDMYS-- 774
Cdd:TIGR01783 518 SLSA----GYTYTDA-EFTEDTNGDTQGNTVPFVPkHTASLWASYAPpvgDNGLTLGGGVQYTGKAYVDGGNTGKVPSyt 592
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639234479 775 -LNLGASKTI-WNGDGTITFNIQDIFNTRRmesFTFNDDFTRRNYMQW-QPRQFSISLSYRF 833
Cdd:TIGR01783 593 vVDLSVRYDLtKKKNLTLALNVNNLFDRDY---YTSGYRWGPSAYIYPgAPRTVGLSVSYDF 651
|
|
| PRK10064 |
PRK10064 |
catecholate siderophore receptor CirA; Provisional |
115-258 |
4.73e-07 |
|
catecholate siderophore receptor CirA; Provisional
Pssm-ID: 236646 [Multi-domain] Cd Length: 663 Bit Score: 53.74 E-value: 4.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 115 ALKGQEAVDSKTQSIQGVTITAAAskpykVELDKKTYDPSTDLISKGG-------TLQDVLTNVPSVAVDTDGT----VS 183
Cdd:PRK10064 16 AISCAWPVLAVDDDGETMVVTASA-----VEQNLKDAPASISVITQEDlqrkpvqNLKDVLKEVPGVQLTNEGDnrkgVS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 184 MRG--NTNVKFLINGKPSsllgidDGANA--------LQSIPADQIEKIEVITNP-SSKFEASGTSGILNIIlkkNKKVG 252
Cdd:PRK10064 91 IRGldSSYTLILIDGKRV------NSRNAvfrhndfdLNWIPVDAIERIEVVRGPmSSLYGSDALGGVVNII---TKKIG 161
|
....*...
gi 639234479 253 --FNGSVT 258
Cdd:PRK10064 162 qkWHGTVT 169
|
|
| Peptidase_M14NE-CP-C_like |
cd11308 |
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, ... |
36-113 |
1.17e-03 |
|
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; This domain is found C-terminal to the M14 carboxypeptidase (CP) N/E subfamily containing zinc-binding enzymes that hydrolyze single C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. The N/E subfamily includes enzymatically active members (carboxypeptidase N, E, M, D, and Z), as well as non-active members (carboxypeptidase-like protein 1, -2, aortic CP-like protein, and adipocyte enhancer binding protein-1) which lack the critical active site and substrate-binding residues considered necessary for activity. The active N/E enzymes fulfill a variety of cellular functions, including prohormone processing, regulation of peptide hormone activity, alteration of protein-protein or protein-cell interactions and transcriptional regulation. For M14 CPs, it has been suggested that this domain may assist in folding of the CP domain, regulate enzyme activity, or be involved in interactions with other proteins or with membranes; for carboxypeptidase M, it may interact with the bradykinin 1 receptor at the cell surface. This domain may also be found in other peptidase families.
Pssm-ID: 200604 [Multi-domain] Cd Length: 76 Bit Score: 38.27 E-value: 1.17e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639234479 36 VSGKITDKNGAAVPYASITFANKTNNAlsdgsMTDDKGNYSLNLTPGTYSLQVETPGFKtfQTEKTITAAGNIGSVQI 113
Cdd:cd11308 2 IKGFVTDATGNPIANATISVEGINHDV-----TTAKDGDYWRLLLPGTYNVTASAPGYQ--PVTKTVTVPNNFSATVV 72
|
|
| TonB-Xanth-Caul |
TIGR01782 |
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ... |
487-631 |
1.76e-03 |
|
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]
Pssm-ID: 273804 [Multi-domain] Cd Length: 845 Bit Score: 41.94 E-value: 1.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 487 LDANKNDYNNIVNTTATNQLIPNYNNTTDYQEVFNAFYVQ----FKSKV-GNfgyqLGLRDELSNVKIDYsNLAGSNINK 561
Cdd:TIGR01782 474 LDAFLNAARGDAAGGGTYTYASTAPNTYTVTEDTTAAYAManfdTGLRLrGN----VGVRYERTDQTSDG-WQSQPAANG 548
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 562 T----------KNYNNLFPSIFLSYDVAKNNQILVNYSRRIDRP-----RAFFMVPFPNYSNNQNIFEGNIDLNPSYVDS 626
Cdd:TIGR01782 549 TgsvlvpvsadRDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPdfgdlAANTSLSDDGTGGTVTVSGGNPDLKPYESDN 628
|
....*
gi 639234479 627 FEVGY 631
Cdd:TIGR01782 629 LDLSL 633
|
|
| PRK13513 |
PRK13513 |
ligand-gated channel protein; |
100-259 |
2.17e-03 |
|
ligand-gated channel protein;
Pssm-ID: 184104 [Multi-domain] Cd Length: 659 Bit Score: 41.68 E-value: 2.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 100 KTITAAGNIGSVQIEALKGQEAVDSKTQSIQGVTIT----------AAASKPYKVELDKKTYDPSTDliskggtlqdVLT 169
Cdd:PRK13513 8 THKAALVIAAAISSQAYAAEKTNTATPTDTMVVTASgfqqriqdapASISVVTREQLENKAYRDVTD----------ALK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 170 NVPSVAVDTDGT---VSMRGNTN--VKFLINGK--------PSSllgidDGANALQSI--PADQIEKIEVITNP-SSKFE 233
Cdd:PRK13513 78 DVPGVVVTGGGStsdISIRGMAAkyTLILVDGKrvdtrstrPNS-----DGSGIEQGWlpPLAAIERIEVVRGPmSSLYG 152
|
170 180
....*....|....*....|....*.
gi 639234479 234 ASGTSGILNIILKKNKKvGFNGSVTG 259
Cdd:PRK13513 153 SDAMGGVINIITRKVQK-EWHGSLRA 177
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
610-817 |
2.19e-03 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 41.77 E-value: 2.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 610 QNIFEGNIDLNPSYVD----SFEVGYSIQKKKFTVNptLYYSRTKDDnkmlvyrpdESLNVFYTKPINLGTSDRYGLDLN 685
Cdd:COG4771 157 TDELEGSVSLGYGSNGngtySGSLSLGGPGDKLSFL--LSGSYRDRD---------GYLDYRNGGFVGNSGYERYNLNAK 225
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 686 FTYDPLSWLKFMGSLDLFGYKTTGIAYYDAVDINKNPIVGTMDFTGSGFSTRARLNTTFKLDKTLSVQLQ--------GQ 757
Cdd:COG4771 226 LGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGNYSLRYNGDLGDNLDLSLYYSrtdrdstnGS 305
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234479 758 YRGAQKTASQNRSDMYSLNLGASKTiWNGDGTITFNIQDIFNTRRMESFTFNDDFTRRNY 817
Cdd:COG4771 306 LGGSTGSFSDSDDTTYGLELDLTYP-LGGNHTLTLGAEYRYDDLDSSSFLGGADASRDTY 364
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