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Conserved domains on  [gi|639234731|ref|WP_024565724|]
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enoyl-CoA hydratase/isomerase family protein [Elizabethkingia anophelis]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
12-351 3.02e-164

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 462.32  E-value: 3.02e-164
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   12 VGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLHDAIVEQReidpkkvPQECLDF 91
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGG-------GEAGRDF 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   92 FSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRMPSAYGLYSGL 171
Cdd:pfam16113  74 FREEYRLNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLAL 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  172 TGARLDGADCRFLGLADYYIESDSKEDLVKALEQADWSGERykTVSEVLEKFSACTKMPESKAAARELFIRKFEGVSTLK 251
Cdd:pfam16113 154 TGARLNGADALAAGLATHYVPSARLPALEEALAALDWSDPA--DVDAVLAEFAEESDPPPSPLAAHREAIDRCFSADTVE 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  252 EFSDILTTYHGKDEWVDAGIKTFASGSPSSAGIIFRQLKLGVKLSLEDVFRSELNLSCQCCIHPDFVEGVRALLVDKDQS 331
Cdd:pfam16113 232 EIIAALEAEADGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRN 311
                         330       340
                  ....*....|....*....|
gi 639234731  332 PKWSPRTQDEVTEEWIDSYF 351
Cdd:pfam16113 312 PKWSPATLEEVTDEMVDAYF 331
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
12-351 3.02e-164

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 462.32  E-value: 3.02e-164
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   12 VGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLHDAIVEQReidpkkvPQECLDF 91
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGG-------GEAGRDF 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   92 FSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRMPSAYGLYSGL 171
Cdd:pfam16113  74 FREEYRLNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLAL 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  172 TGARLDGADCRFLGLADYYIESDSKEDLVKALEQADWSGERykTVSEVLEKFSACTKMPESKAAARELFIRKFEGVSTLK 251
Cdd:pfam16113 154 TGARLNGADALAAGLATHYVPSARLPALEEALAALDWSDPA--DVDAVLAEFAEESDPPPSPLAAHREAIDRCFSADTVE 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  252 EFSDILTTYHGKDEWVDAGIKTFASGSPSSAGIIFRQLKLGVKLSLEDVFRSELNLSCQCCIHPDFVEGVRALLVDKDQS 331
Cdd:pfam16113 232 EIIAALEAEADGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRN 311
                         330       340
                  ....*....|....*....|
gi 639234731  332 PKWSPRTQDEVTEEWIDSYF 351
Cdd:pfam16113 312 PKWSPATLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
2-353 8.88e-130

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 375.31  E-value: 8.88e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   2 DLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLHDAIveqREIDP 81
Cdd:PRK05617   3 DEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAA---RAGDP 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  82 kkvpQECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRM 161
Cdd:PRK05617  80 ----LAADRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 162 PSAYGLYSGLTGARLDGADCRFLGLADYYIESDSKEDLVKALEQADW-SGERykTVSEVLEKFSAcTKMPESKAAARELF 240
Cdd:PRK05617 156 PGALGTYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWdSGAD--VVDAALAAFAT-PAPASELAAQRAWI 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 241 IRKFEGvSTLKEFSDILTTYhgKDEWVDAGIKTFASGSPSSAGIIFRQLKLGVKLSLEDVFRSELNLSCQCCIHPDFVEG 320
Cdd:PRK05617 233 DECFAG-DTVEDIIAALEAD--GGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEG 309
                        330       340       350
                 ....*....|....*....|....*....|...
gi 639234731 321 VRALLVDKDQSPKWSPRTQDEVTEEWIDSYFSP 353
Cdd:PRK05617 310 VRAVLIDKDRNPKWSPATLEDVTPEDVEAFFAP 342
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
4-203 2.61e-50

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 166.97  E-value: 2.61e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAIVEQREIDpkk 83
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEAR--- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  84 vpqeclDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFL-NRMP 162
Cdd:cd06558   77 ------AFIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLpRLVG 150
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 639234731 163 SAYGLYSGLTGARLDGADCRFLGLADYYIESDSKEDLVKAL 203
Cdd:cd06558  151 PARARELLLTGRRISAEEALELGLVDEVVPDEELLAAALEL 191
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
4-325 8.00e-46

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 157.25  E-value: 8.00e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKklhdaiveqrEIDPKK 83
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLK----------ELAAAA 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  84 VPQECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFL-NRMP 162
Cdd:COG1024   70 DPEEARAFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLpRLVG 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 163 SAYGLYSGLTGARLDGADCRFLGLADYYIESDskedlvkaleqadwsgeryktvsEVLekfsactkmpeskAAARELfir 242
Cdd:COG1024  150 LARAKELLLTGRRIDAEEALELGLVNRVVPDD-----------------------ELL-------------AAALAL--- 190
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 243 kfegvstlkefsdilttyhgkdewvdagIKTFASGSPSSAGIIFRQLKLGVKLSLEDVFRSELNLSCQCCIHPDFVEGVR 322
Cdd:COG1024  191 ----------------------------AARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242

                 ...
gi 639234731 323 ALL 325
Cdd:COG1024  243 AFL 245
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
4-192 8.50e-14

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 72.56  E-value: 8.50e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731    4 ILTEIKNKVGFITLNSEKT-LNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLHdaiVEQREIDPK 82
Cdd:TIGR02441  15 RHYEVKGDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIA---ACKTAQEVT 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   83 KVPQECLDFFSKeykvdyaIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTE--KSKLAMPEITIGLYPDVGGTWFLNR 160
Cdd:TIGR02441  92 QLSQEGQEMFER-------IEKSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGTQRLPK 164
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 639234731  161 M---PSAYGLYsgLTGARLDGADCRFLGLADYYIE 192
Cdd:TIGR02441 165 LtgvPAALDMM--LTGKKIRADRAKKMGIVDQLVD 197
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
12-351 3.02e-164

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 462.32  E-value: 3.02e-164
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   12 VGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLHDAIVEQReidpkkvPQECLDF 91
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGG-------GEAGRDF 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   92 FSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRMPSAYGLYSGL 171
Cdd:pfam16113  74 FREEYRLNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLAL 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  172 TGARLDGADCRFLGLADYYIESDSKEDLVKALEQADWSGERykTVSEVLEKFSACTKMPESKAAARELFIRKFEGVSTLK 251
Cdd:pfam16113 154 TGARLNGADALAAGLATHYVPSARLPALEEALAALDWSDPA--DVDAVLAEFAEESDPPPSPLAAHREAIDRCFSADTVE 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  252 EFSDILTTYHGKDEWVDAGIKTFASGSPSSAGIIFRQLKLGVKLSLEDVFRSELNLSCQCCIHPDFVEGVRALLVDKDQS 331
Cdd:pfam16113 232 EIIAALEAEADGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRN 311
                         330       340
                  ....*....|....*....|
gi 639234731  332 PKWSPRTQDEVTEEWIDSYF 351
Cdd:pfam16113 312 PKWSPATLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
2-353 8.88e-130

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 375.31  E-value: 8.88e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   2 DLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLHDAIveqREIDP 81
Cdd:PRK05617   3 DEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAA---RAGDP 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  82 kkvpQECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRM 161
Cdd:PRK05617  80 ----LAADRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 162 PSAYGLYSGLTGARLDGADCRFLGLADYYIESDSKEDLVKALEQADW-SGERykTVSEVLEKFSAcTKMPESKAAARELF 240
Cdd:PRK05617 156 PGALGTYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWdSGAD--VVDAALAAFAT-PAPASELAAQRAWI 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 241 IRKFEGvSTLKEFSDILTTYhgKDEWVDAGIKTFASGSPSSAGIIFRQLKLGVKLSLEDVFRSELNLSCQCCIHPDFVEG 320
Cdd:PRK05617 233 DECFAG-DTVEDIIAALEAD--GGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEG 309
                        330       340       350
                 ....*....|....*....|....*....|...
gi 639234731 321 VRALLVDKDQSPKWSPRTQDEVTEEWIDSYFSP 353
Cdd:PRK05617 310 VRAVLIDKDRNPKWSPATLEDVTPEDVEAFFAP 342
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
1-353 3.66e-77

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 242.40  E-value: 3.66e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAiveqreid 80
Cdd:PLN02874  10 EEVVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAG-RAFSAGGDLKMFYDG-------- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  81 pKKVPQECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNR 160
Cdd:PLN02874  81 -RESDDSCLEVVYRMYWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSR 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 161 MPSAYGLYSGLTGARLDGADCRFLGLADYYIESDSKEDLVKALEQADwSGERyKTVSEVLEKFSACTKMPESKAAARELF 240
Cdd:PLN02874 160 LPGHLGEYLALTGARLNGKEMVACGLATHFVPSEKLPELEKRLLNLN-SGDE-SAVQEAIEEFSKDVQADEDSILNKQSW 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 241 IRKFEGVSTLKEFSDILTTYHGKD--EWVDAGIKTFASGSPSSAGIIFRQLKLGVKLSLEDVFRSELNLSCQC---CIHP 315
Cdd:PLN02874 238 INECFSKDTVEEIIKAFESEASKTgnEWIKETLKGLRRSSPTGLKITLRSIREGRKQSLAECLKKEFRLTMNIlrsTVSD 317
                        330       340       350
                 ....*....|....*....|....*....|....*...
gi 639234731 316 DFVEGVRALLVDKDQSPKWSPRTQDEVTEEWIDSYFSP 353
Cdd:PLN02874 318 DVYEGIRALVIDKDNAPKWNPSTLDEVTDEKVDLVFQP 355
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
4-364 6.99e-62

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 203.02  E-value: 6.99e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKklhdAIVEQREIDPKK 83
Cdd:PLN02988  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVA----AVVRDIEQGNWR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  84 VPQeclDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRMPS 163
Cdd:PLN02988  86 LGA---NFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPG 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 164 AYGLYSGLTGARLDGADCRFLGLADYYIESDSKEDLVKALEQADWSGERYktVSEVLEKFSACTKMPESKAAARELFIRK 243
Cdd:PLN02988 163 FFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTF--ASTILDAYTQHPRLKPQSAYHRLDVIDR 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 244 FEGVSTLKEFSDIL--TTYHGKDEWVDAGIKTFASGSPSSAGIIFRQLKLGVKLSLEDVFRSELNLSCQCC---IHPDFV 318
Cdd:PLN02988 241 CFSRRTVEEIISALerEATQEADGWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMkgeISKDFV 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 639234731 319 EGVRALLVDKDQSPKWSPRTQDEVTEEWIDSYFSPV-----WNIDKHPLKN 364
Cdd:PLN02988 321 EGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFERVeeeeeWDDLKLPPRN 371
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
2-354 1.62e-58

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 194.81  E-value: 1.62e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   2 DLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAIVEQREidp 81
Cdd:PLN02851  42 DQVLVEGRAKSRAAILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSG-RAFCSGADVVSLYHLINEGNV--- 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  82 kkvpQECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRM 161
Cdd:PLN02851 118 ----EECKLFFENLYKFVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRL 193
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 162 PSAYGLYSGLTGARLDGADCRFLGLADYY--------IE-------SDSKEDLVKALEQadWSGERYKTVSEVLEKFSAc 226
Cdd:PLN02851 194 PGYLGEYLALTGQKLNGVEMIACGLATHYclnarlplIEerlgkllTDDPAVIEDSLAQ--YGDLVYPDKSSVLHKIET- 270
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 227 tkmpeskaaarelfIRKFEGVSTLKEFSDILTTYHGK--DEWVDAGIKTFASGSPSSAGIIFRQLKLGVKLSLEDVFRSE 304
Cdd:PLN02851 271 --------------IDKCFGHDTVEEIIEALENEAASsyDEWCKKALKKIKEASPLSLKVTLQSIREGRFQTLDQCLARE 336
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 639234731 305 LNLS---CQCCIHPDFVEGVRALLVDKDQSPKWSPRTQDEVTEEWIDSYFSPV 354
Cdd:PLN02851 337 YRISlcgVSKWVSGDFCEGVRARLVDKDFAPKWDPPSLGEVSKDMVDCYFTPL 389
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
17-351 1.33e-51

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 176.80  E-value: 1.33e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  17 LNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHdaiveqrEIDPKKVPQECLDFFSKEY 96
Cdd:PLN02157  52 LNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSG-RAFCAGGDIVSLY-------HLRKRGSPDAIREFFSSLY 123
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  97 KVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRMPSAYGLYSGLTGARL 176
Cdd:PLN02157 124 SFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGRLGEYLGLTGLKL 203
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 177 DGADCRFLGLADYYIESDS---KEDLVKALEQADWSgerykTVSEVLEKfSACTKMPESKAAAREL-FIRKFEGVSTLKE 252
Cdd:PLN02157 204 SGAEMLACGLATHYIRSEEipvMEEQLKKLLTDDPS-----VVESCLEK-CAEVAHPEKTGVIRRIdLLEKCFSHDTVEE 277
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 253 FSDIL--TTYHGKDEWVDAGIKTFASGSPSSAGIIFRQLKLGVKLSLEDVFRSELNLSCQCCIHP---DFVEGVRALLVD 327
Cdd:PLN02157 278 IIDSLeiEAGRRKDTWCITTLRRLKESSPLSLKVALRSIREGRLQTLDQCLIREYRMSLQGLIGPmsgNFCEGVRARLID 357
                        330       340
                 ....*....|....*....|....
gi 639234731 328 KDQSPKWSPRTQDEVTEEWIDSYF 351
Cdd:PLN02157 358 KDEAPKWDPPSLEKVSEDMVDDYF 381
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
4-203 2.61e-50

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 166.97  E-value: 2.61e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAIVEQREIDpkk 83
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEAR--- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  84 vpqeclDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFL-NRMP 162
Cdd:cd06558   77 ------AFIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLpRLVG 150
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 639234731 163 SAYGLYSGLTGARLDGADCRFLGLADYYIESDSKEDLVKAL 203
Cdd:cd06558  151 PARARELLLTGRRISAEEALELGLVDEVVPDEELLAAALEL 191
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
4-325 8.00e-46

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 157.25  E-value: 8.00e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKklhdaiveqrEIDPKK 83
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLK----------ELAAAA 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  84 VPQECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFL-NRMP 162
Cdd:COG1024   70 DPEEARAFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLpRLVG 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 163 SAYGLYSGLTGARLDGADCRFLGLADYYIESDskedlvkaleqadwsgeryktvsEVLekfsactkmpeskAAARELfir 242
Cdd:COG1024  150 LARAKELLLTGRRIDAEEALELGLVNRVVPDD-----------------------ELL-------------AAALAL--- 190
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 243 kfegvstlkefsdilttyhgkdewvdagIKTFASGSPSSAGIIFRQLKLGVKLSLEDVFRSELNLSCQCCIHPDFVEGVR 322
Cdd:COG1024  191 ----------------------------AARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242

                 ...
gi 639234731 323 ALL 325
Cdd:COG1024  243 AFL 245
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
1-186 3.20e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 108.03  E-value: 3.20e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKklhdaiveqreiD 80
Cdd:PRK06688   4 VTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAG-RAFSAGGDIK------------D 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  81 PKKVPQECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNR 160
Cdd:PRK06688  71 FPKAPPKPPDELAPVNRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPR 150
                        170       180
                 ....*....|....*....|....*....
gi 639234731 161 M---PSAYGLYsgLTGARLDGADCRFLGL 186
Cdd:PRK06688 151 LigrARAAEML--LLGEPLSAEEALRIGL 177
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
1-207 3.07e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 102.89  E-value: 3.07e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEI-KNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKklhdaivEQREI 79
Cdd:PRK07657   2 LQNISVDYvTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLK-------ERAGM 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  80 DPKKVPQECldffSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTwflN 159
Cdd:PRK07657  75 NEEQVRHAV----SLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGT---Q 147
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 639234731 160 RMPSAYGLYSG----LTGARLDGADCRFLGLADYYIESDSKEDlvKALEQAD 207
Cdd:PRK07657 148 RLPRLIGVGRAkeliYTGRRISAQEAKEIGLVEFVVPAHLLEE--KAIEIAE 197
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
2-161 1.39e-23

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 98.29  E-value: 1.39e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   2 DLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLHDAIVEQREIDP 81
Cdd:PRK05980   3 DTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADVAL 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  82 KkvpqeclDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRM 161
Cdd:PRK05980  83 R-------DFVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRL 155
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
7-206 1.34e-21

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 92.42  E-value: 1.34e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731    7 EIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGaGEKAFCAGGDVKKLHDAIVEQrEIDPKKVPQ 86
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAH-QALYRENVL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   87 ECLDffskeykvdyAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFL-NRMPSAY 165
Cdd:pfam00378  79 DLWT----------LLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLpRIIGHSK 148
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 639234731  166 GLYSGLTGARLDGADCRFLGLADyyiESDSKEDLV-KALEQA 206
Cdd:pfam00378 149 AMEMLLLGRRISAQEALKWGLVD---KVVPEDQLLdEARELA 187
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
2-188 4.56e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 91.31  E-value: 4.56e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   2 DLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLhdaivEQREIDP 81
Cdd:PRK06127  11 GKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQF-----EESRSDA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  82 kkvpqECLDFFSKEYKVDY-AIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNR 160
Cdd:PRK06127  86 -----EAVAAYEQAVEAAQaALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVD 160
                        170       180       190
                 ....*....|....*....|....*....|
gi 639234731 161 M--PSAYGLYSgLTGARLDGADCRFLGLAD 188
Cdd:PRK06127 161 LvgPSAAKDLF-YTARRFDAAEALRIGLVH 189
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
1-161 2.78e-20

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 89.04  E-value: 2.78e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDL--ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLHDAIVEQRE 78
Cdd:PRK05809   1 MELknVILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEGR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  79 idpkkvpqeclDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFL 158
Cdd:PRK05809  81 -----------KFGLLGNKVFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRL 149

                 ...
gi 639234731 159 NRM 161
Cdd:PRK05809 150 ARI 152
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
4-252 3.93e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 88.56  E-value: 3.93e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAgEKAFCAGGDVKKLHDaiveqreidpkk 83
Cdd:PRK05862   6 ILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGS-EKAFAAGADIKEMAD------------ 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  84 vpqecLDFfSKEYKVDY-----AIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTwfl 158
Cdd:PRK05862  73 -----LSF-MDVYKGDYitnweKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGS--- 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 159 NRMPSAYGLYSG----LTGARLDGADCRFLGLADYYIESDskedlvKALEQAdwsgeryKTVSEVLEKFSACTKMpeska 234
Cdd:PRK05862 144 QRLTRAVGKAKAmdlcLTGRMMDAAEAERAGLVSRVVPAD------KLLDEA-------LAAATTIASFSLPAVM----- 205
                        250
                 ....*....|....*...
gi 639234731 235 AARELFIRKFEgvSTLKE 252
Cdd:PRK05862 206 MAKEAVNRAYE--TTLAE 221
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
1-187 1.71e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 80.93  E-value: 1.71e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAIVEQREID 80
Cdd:PRK05870   2 MDPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAG-KAFCAGADLTALGAAPGRPAEDG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  81 PKKVpqecldffskeYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNR 160
Cdd:PRK05870  81 LRRI-----------YDGFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQR 149
                        170       180       190
                 ....*....|....*....|....*....|.
gi 639234731 161 mpsAYG----LYSGLTGARLDGADCRFLGLA 187
Cdd:PRK05870 150 ---AVGpqvaRAALLFGMRFDAEAAVRHGLA 177
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
1-188 1.60e-16

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 78.20  E-value: 1.60e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSeKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAIveqreid 80
Cdd:PRK06495   3 MSQLKLEVSDHVAVVTLDN-PPVNALSRELRDELIAVFDEISERPDVRVVVLTGAG-KVFCAGADLKGRPDVI------- 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  81 pkKVPQECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLypdVGGTWFLNR 160
Cdd:PRK06495  74 --KGPGDLRAHNRRTRECFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMR 148
                        170       180
                 ....*....|....*....|....*....
gi 639234731 161 M-PSAYGLYSGLTGARLDGADCRFLGLAD 188
Cdd:PRK06495 149 LfGHSLTRRMMLTGYRVPAAELYRRGVIE 177
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
1-252 1.93e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 78.14  E-value: 1.93e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTlNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDaiVEQREiD 80
Cdd:PRK07658   1 MKFLSVRVEDHVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGEG-RFFSAGADIKEFTS--VTEAE-Q 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  81 PKKVPQECLDFFSKeykvdyaIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNR 160
Cdd:PRK07658  76 ATELAQLGQVTFER-------VEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPR 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 161 ---MPSAYGLYsgLTGARLDGADCRFLGLADYYIESDSKEDLVKALEQaDWSGERYKTVSEVLEKFSACTKMPESKAAAR 237
Cdd:PRK07658 149 yvgKAKALEMM--LTSEPITGAEALKWGLVNGVFPEETLLDDAKKLAK-KIAGKSPATTRAVLELLQTTKSSSYYEGVKR 225
                        250       260
                 ....*....|....*....|...
gi 639234731 238 E--LFIRKF------EGVSTLKE 252
Cdd:PRK07658 226 EakIFGEVFtsedakEGVQAFLE 248
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
1-197 8.10e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 76.22  E-value: 8.10e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIfLQGAGeKAFCAGGDVKKLHDaiveqrEID 80
Cdd:PRK07659   5 MESVVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESSAHIVV-LRGNG-RGFSAGGDIKMMLS------SND 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  81 PKKVpQECLDFFSKeykVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNR 160
Cdd:PRK07659  77 ESKF-DGVMNTISE---IVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQK 152
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 639234731 161 M---PSAYGLYsgLTGARLDGADCRFLGLADYYIESDSKE 197
Cdd:PRK07659 153 RvgeNKAKQII--WEGKKLSATEALDLGLIDEVIGGDFQT 190
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
4-186 1.62e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 75.46  E-value: 1.62e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEV-VCIfLQGAGEKAFCAGGDVKklhdaivEQREIDPK 82
Cdd:PRK06494   6 STVERKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQwVAI-VTGAGDKAFSAGNDLK-------EQAAGGKR 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  83 KVPQECLDFFSKEYKVDyaihtypKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGtwfLNRMP 162
Cdd:PRK06494  78 GWPESGFGGLTSRFDLD-------KPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGG---LHRLP 147
                        170       180
                 ....*....|....*....|....*...
gi 639234731 163 SAYGLYSG----LTGARLDGADCRFLGL 186
Cdd:PRK06494 148 RQIGLKRAmgmiLTGRRVTAREGLELGF 175
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
1-203 2.83e-15

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 74.68  E-value: 2.83e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWElSDEVVCIFLQ-GAGEKAFCAGGDVKKLhdaiveqrei 79
Cdd:PRK11423   3 MQYVNVVTINKIATITFNNPAKRNALSKVLIDDLMQALSDLN-RPEIRVVILRaPSGSKVWSAGHDIHEL---------- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  80 dpkkvPQECLDFFSkeY-----KVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGL-YPDVG 153
Cdd:PRK11423  72 -----PSGGRDPLS--YddplrQILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVpYNLSG 144
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 639234731 154 GTWFLNRMPSAYGLYSGLTGARLDGADCRFLGLADYYIESDSKEDLVKAL 203
Cdd:PRK11423 145 ILNFTNDAGFHIVKEMFFTASPITAQRALAVGILNHVVEVEELEDFTLQM 194
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
4-218 1.19e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 72.85  E-value: 1.19e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWElSDEVVCIFLQGAGEKAFCAGGDVKKLHDAiVEQREIdpkk 83
Cdd:PRK07260   4 IIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAE-EDPSVRFLLINANGKVFSVGGDLVEMKRA-VDEDDV---- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  84 vpQECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRmps 163
Cdd:PRK07260  78 --QSLVKIAELVNEISFAIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTR--- 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639234731 164 AYGL----YSGLTGARLDGADCRFLGLADYYIESD----SKEDLVKALEQAdwSGERYKTVSE 218
Cdd:PRK07260 153 AIGLnratHLAMTGEALTAEKALEYGFVYRVAESEklekTCEQLLKKLRRG--SSNSYAAIKS 213
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
3-206 2.88e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 72.01  E-value: 2.88e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   3 LILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGaGEKAFCAGGDVKKLHDAiveqreiDPK 82
Cdd:PRK08138   9 VLLERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTG-GEKVFAAGADIKEFATA-------GAI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  83 KVPQEcldffSKEYKVDyAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRmp 162
Cdd:PRK08138  81 EMYLR-----HTERYWE-AIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVR-- 152
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 639234731 163 sAYGLYSG----LTGARLDGADCRFLGLADYYIESDskEDLVKALEQA 206
Cdd:PRK08138 153 -AVGKFKAmrmaLTGCMVPAPEALAIGLVSEVVEDE--QTLPRALELA 197
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
1-177 6.02e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 71.10  E-value: 6.02e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWElSDEVVCIFLQGAGeKAFCAGGDvkkLHDaiveqREID 80
Cdd:PRK08140   3 YETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGAG-RGFCAGQD---LAD-----RDVT 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  81 PKKVPQECLDFFSKEYK-VDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLN 159
Cdd:PRK08140  73 PGGAMPDLGESIETFYNpLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLP 152
                        170       180
                 ....*....|....*....|.
gi 639234731 160 R---MPSAYGLysGLTGARLD 177
Cdd:PRK08140 153 RlvgMARALGL--ALLGEKLS 171
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
4-192 8.50e-14

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 72.56  E-value: 8.50e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731    4 ILTEIKNKVGFITLNSEKT-LNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLHdaiVEQREIDPK 82
Cdd:TIGR02441  15 RHYEVKGDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIA---ACKTAQEVT 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   83 KVPQECLDFFSKeykvdyaIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTE--KSKLAMPEITIGLYPDVGGTWFLNR 160
Cdd:TIGR02441  92 QLSQEGQEMFER-------IEKSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGTQRLPK 164
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 639234731  161 M---PSAYGLYsgLTGARLDGADCRFLGLADYYIE 192
Cdd:TIGR02441 165 LtgvPAALDMM--LTGKKIRADRAKKMGIVDQLVD 197
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
15-186 9.00e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 70.41  E-value: 9.00e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  15 ITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLhdaiVEQREIDPKkVPQECLDFFSK 94
Cdd:PRK07511  16 LTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAG-GFFCAGGNLNRL----LENRAKPPS-VQAASIDGLHD 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  95 EYKvdyAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRM-PSAYGLYSGLTG 173
Cdd:PRK07511  90 WIR---AIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARAlPRQLATELLLEG 166
                        170
                 ....*....|...
gi 639234731 174 ARLDGADCRFLGL 186
Cdd:PRK07511 167 KPISAERLHALGV 179
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
1-155 2.14e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 69.52  E-value: 2.14e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAIVEQREID 80
Cdd:PRK07509   2 MDRVSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEG-GAFCAGLDVKSVASSPGNAVKLL 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639234731  81 PKKVPQECLDFfskeYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGT 155
Cdd:PRK07509  81 FKRLPGNANLA----QRVSLGWRRLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGT 151
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
1-206 3.99e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 68.80  E-value: 3.99e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDV---KKLHDAIVEQR 77
Cdd:PRK05995   3 YETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAG-KAFCAGADLnwmKKMAGYSDDEN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  78 EIDPKKVPQecldffskeykVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWF 157
Cdd:PRK05995  82 RADARRLAD-----------MLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYV 150
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 639234731 158 LNRMPSAYGLYSGLTGARLDGADCRFLGLADYYIESDSKEDLVKALEQA 206
Cdd:PRK05995 151 IRAMGERAARRYFLTAERFDAAEALRLGLVHEVVPAEALDAKVDELLAA 199
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
1-160 4.16e-13

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 68.64  E-value: 4.16e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAgEKAFCAGGDVKKLHDAIVEQREID 80
Cdd:PRK09674   1 MSELLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGN-ARFFAAGADLNEMAEKDLAATLND 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  81 PKKVPQECLDFFSKeykvdyaihtypkPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNR 160
Cdd:PRK09674  80 PRPQLWQRLQAFNK-------------PLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIR 146
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
1-186 1.27e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 67.30  E-value: 1.27e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLP-MIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAiVEQREI 79
Cdd:PRK09245   2 TDFLLVERDGHIVTLTMNRPETRNALSDNdAVDALVAACAAINADRSVRAVILTGAG-TAFSSGGNVKDMRAR-VGAFGG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  80 DPKKVPQecldffskEYKvdYAIHTYPK-------PVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDV 152
Cdd:PRK09245  80 SPADIRQ--------GYR--HGIQRIPLalynlevPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGD 149
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 639234731 153 GGTWFLNR---MPSAYGLysGLTGARLDGADCRFLGL 186
Cdd:PRK09245 150 GGAWLLPRiigMARAAEM--AFTGDAIDAATALEWGL 184
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
15-205 1.38e-12

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 67.03  E-value: 1.38e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  15 ITLNSEKTlNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKklhdAIVEQREIDPKKVP------QEC 88
Cdd:PRK03580  16 ITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLK----AAAEGEAPDADFGPggfaglTEI 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  89 LDFfskeykvdyaihtyPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFL-NRMPSAYGL 167
Cdd:PRK03580  91 FDL--------------DKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLpKRLPPAIAN 156
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 639234731 168 YSGLTGARLDGADCRFLGLADYYIESDSKEDLVKALEQ 205
Cdd:PRK03580 157 EMVMTGRRMDAEEALRWGIVNRVVPQAELMDRARELAQ 194
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
3-245 2.26e-12

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 66.50  E-value: 2.26e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   3 LILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAiveqREidpk 82
Cdd:PRK08139  12 LLLREDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAG-KAFCAGHDLKEMRAA----RG---- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  83 kvpqecLDFFSKEY----KVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLY---PDVGgt 155
Cdd:PRK08139  83 ------LAYFRALFarcsRVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVA-- 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 156 wfLNR-MPSAYGLYSGLTGARLDGADCRFLGLADYYIESDSKEDLVKALEQadwsgeryktvsevlekfSACTKMPESKA 234
Cdd:PRK08139 155 --LSRnVPRKQAMEMLLTGEFIDAATAREWGLVNRVVPADALDAAVARLAA------------------VIAAKSPAAVR 214
                        250
                 ....*....|.
gi 639234731 235 AARELFIRKFE 245
Cdd:PRK08139 215 IGKEAFYRQAE 225
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
12-203 8.15e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 64.67  E-value: 8.15e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  12 VGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKklhdaivEQREIDPKKVPQecldF 91
Cdd:PRK06143  17 VATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIK-------EMATLDQASAEA----F 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  92 FSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLyPDVGGTWFLNRM----PSAYGL 167
Cdd:PRK06143  86 ISRLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVIHAALLPRLigwaRTRWLL 164
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 639234731 168 ysgLTGARLDGADCRFLGLADYYIESDSKEDLVKAL 203
Cdd:PRK06143 165 ---LTGETIDAAQALAWGLVDRVVPLAELDAAVERL 197
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
9-199 8.53e-12

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 64.92  E-value: 8.53e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   9 KNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLhDAIVEQREIDPKKVPQEC 88
Cdd:PLN02664  15 NSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAG-DHFCSGIDLKTL-NSISEQSSSGDRGRSGER 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  89 LdffskEYKVDY------AIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGtwfLNRMP 162
Cdd:PLN02664  93 L-----RRKIKFlqdaitAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGT---LQRLP 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 639234731 163 SAYGLYS----GLTGARLDGADCRFLGLADYYIesDSKEDL 199
Cdd:PLN02664 165 SIVGYGNamelALTGRRFSGSEAKELGLVSRVF--GSKEDL 203
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
2-206 2.23e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 63.50  E-value: 2.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   2 DLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKmwELSDEVVCIFLQGAGEKaFCAGGDvkklhdaIVEQREIDP 81
Cdd:PRK08150   2 SLVSYELDGGVATIGLNRPAKRNALNDGLIAALRAAFA--RLPEGVRAVVLHGEGDH-FCAGLD-------LSELRERDA 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  82 KKVPQECLDFFSKEYKVDYAihtyPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWflnRM 161
Cdd:PRK08150  72 GEGMHHSRRWHRVFDKIQYG----RVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSV---RV 144
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 639234731 162 PSAYGLYSG----LTGARLDGADCRFLGLADYYIEsdSKEDLVKALEQA 206
Cdd:PRK08150 145 PRLIGVARMtdmmLTGRVYDAQEGERLGLAQYLVP--AGEALDKAMELA 191
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
12-186 3.33e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 63.15  E-value: 3.33e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  12 VGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHD---AIVEQREIDPKKVpQEC 88
Cdd:PRK07468  15 VATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAG-KSFCAGGDLGWMRAqmtADRATRIEEARRL-AMM 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  89 LDffskeykvdyAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRMPSAYGLY 168
Cdd:PRK07468  93 LK----------ALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGEANARR 162
                        170
                 ....*....|....*...
gi 639234731 169 SGLTGARLDGADCRFLGL 186
Cdd:PRK07468 163 VFMSARLFDAEEAVRLGL 180
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
1-142 4.54e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 62.70  E-value: 4.54e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLHDAiveqreid 80
Cdd:PRK06144   7 TDELLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAF-------- 78
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639234731  81 pkKVPQECLDFfskEYKVDY---AIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMP 142
Cdd:PRK06144  79 --STAEDAVAY---ERRIDRvlgALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP 138
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
1-186 9.61e-11

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 61.62  E-value: 9.61e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDvkkLHDAIveqreiD 80
Cdd:PRK07827   5 DTLVRYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTG-GTFCAGAD---LSEAG------G 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  81 PKKVPQECLDFFSKEY-KVDYAIHTYPKPVIVWGSGIVMGGGIGLmVGASHRIVT-EKSKLAMPEITIGLYPDVGGTWFL 158
Cdd:PRK07827  75 GGGDPYDAAVARAREMtALLRAIVELPKPVIAAIDGHVRAGGFGL-VGACDIVVAgPESTFALTEARIGVAPAIISLTLL 153
                        170       180
                 ....*....|....*....|....*....
gi 639234731 159 NRMPS-AYGLYSgLTGARLDGADCRFLGL 186
Cdd:PRK07827 154 PRLSPrAAARYY-LTGEKFGAAEAARIGL 181
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
15-207 2.43e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 60.50  E-value: 2.43e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  15 ITLNSEKTLNSLSLPMieqLGAVLKMWELSD---EVVCIFLQGAGeKAFCAGGDVKKLhdaiveqreidPKKVPQeclDF 91
Cdd:PRK07799  18 VTMNRPEARNALSTEM---LRIMVDAWDRVDndpDIRSCILTGAG-GAFCAGMDLKAA-----------TKKPPG---DS 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  92 FSKEYKVDYAI------HTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNR-MPSA 164
Cdd:PRK07799  80 FKDGSYDPSRIdallkgRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRqIPYT 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 639234731 165 YGLYSGLTGARLDGADCRFLGLADYYIESDSKedLVKALEQAD 207
Cdd:PRK07799 160 VACDLLLTGRHITAAEAKEIGLIGHVVPDGQA--LDKALELAE 200
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
2-186 2.59e-10

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 60.41  E-value: 2.59e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   2 DLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEkAFCAGGDVKKLHDAIVEQREIDP 81
Cdd:PRK09120   8 DTVKVEVEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGD-AWSAGMDLKEYFRETDAQPEILQ 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  82 KKVPQECLDFFSKeykvdyaIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFL-NR 160
Cdd:PRK09120  87 ERIRREAYGWWRR-------LRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMaDT 159
                        170       180
                 ....*....|....*....|....*.
gi 639234731 161 MPSAYGLYSGLTGARLDGADCRFLGL 186
Cdd:PRK09120 160 VGHRDALYYIMTGETFTGRKAAEMGL 185
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
1-170 3.39e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 60.41  E-value: 3.39e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAIVEQREID 80
Cdd:PRK08260   3 YETIRYDVADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAG-RAFCAGADLSAGGNTFDLDAPRT 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  81 PKKVPQECLDFFSKEY------KVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGG 154
Cdd:PRK08260  82 PVEADEEDRADPSDDGvrdgggRVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAAS 161
                        170       180
                 ....*....|....*....|
gi 639234731 155 TWFLNR---MPSAYGL-YSG 170
Cdd:PRK08260 162 SWFLPRlvgLQTALEWvYSG 181
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
3-274 9.69e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 58.64  E-value: 9.69e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   3 LILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAIVEqreidpk 82
Cdd:PRK06072   1 MIKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEG-RAFCVGADLSEFAPDFAI------- 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  83 kvpqeclDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRMP 162
Cdd:PRK06072  73 -------DLRETFYPIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLT 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 163 SAYGLYSGLTGARLDGADCRFLGLADYyiesdSKEDLVKALEQADwsgeryKTVSEVLEKFSACTKMpeskaAARELfir 242
Cdd:PRK06072 146 GQRFYEILVLGGEFTAEEAERWGLLKI-----SEDPLSDAEEMAN------RISNGPFQSYIAAKRM-----INLVL--- 206
                        250       260       270
                 ....*....|....*....|....*....|..
gi 639234731 243 kFEGVSTLKEFSDILTTYHGKDEWVDAGIKTF 274
Cdd:PRK06072 207 -YNDLEEFLEYESAIQGYLGKTEDFKEGISSF 237
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
1-248 2.19e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 57.62  E-value: 2.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLN--SEKTLNSLSLPMIEQLGAVLkmwELSDEVVCIFLQGAGEKAFCAGGDVKKLHDaiveqre 78
Cdd:PRK09076   2 MIELDLEIDGHVAILTLNnpPANTWTADSLQALKQLVLEL---NADKDVYALVITGDGEKFFSAGADLNLFAD------- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  79 iDPKKVPQECLDFFSKEYKvdyAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFL 158
Cdd:PRK09076  72 -GDKAVAREMARRFGEAFE---ALSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNL 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 159 ---------NRMPsayglysgLTGARLDGADCRFLGLAdyyiesdskEDLV---KALEQADWSGERYKTVSEVleKFSAC 226
Cdd:PRK09076 148 pwlvgegwaKRMI--------LCGERVDAATALRIGLV---------EEVVekgEAREAALALAQKVANQSPS--AVAAC 208
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 639234731 227 TK-------MPESKAAA--RELFIRKF------EGVS 248
Cdd:PRK09076 209 KTliqaarnGPRAAALAleRELFVDLFdtedqrEGVN 245
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
1-186 2.27e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 57.29  E-value: 2.27e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHD----AIVEQ 76
Cdd:PRK06190   3 EPILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGAD-PAFCAGLDLKELGGdgsaYGAQD 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  77 REIDP-KKVPQecldffskeykvdyaihtYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPdvggT 155
Cdd:PRK06190  82 ALPNPsPAWPA------------------MRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILP----G 139
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 639234731 156 WFLN-RMPSAYGLYSG----LTGARLDGADCRFLGL 186
Cdd:PRK06190 140 WGLSvRLPQKVGIGRArrmsLTGDFLDAADALRAGL 175
PLN02888 PLN02888
enoyl-CoA hydratase
3-216 2.64e-09

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 57.45  E-value: 2.64e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   3 LILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAI---VEQREI 79
Cdd:PLN02888  11 ILVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSG-RAFCSGVDLTAAEEVFkgdVKDVET 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  80 DPKKVPQECldffskeykvdyaihtyPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLN 159
Cdd:PLN02888  90 DPVAQMERC-----------------RKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLS 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639234731 160 RMPSAY-GLYSGLTGARLDGADCRFLGLADYYIesDSKEDLVKALEQADWSGE-------RYKTV 216
Cdd:PLN02888 153 RIIGANrAREVSLTAMPLTAETAERWGLVNHVV--EESELLKKAREVAEAIIKnnqgmvlRYKSV 215
PLN02600 PLN02600
enoyl-CoA hydratase
15-206 3.05e-09

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 57.12  E-value: 3.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  15 ITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKklhdaivEQREIDPKKVpqeclDFFSK 94
Cdd:PLN02600   8 LRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLK-------ERRKMSPSEV-----QKFVN 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  95 EYKVDY-AIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTwflNRMPSAYGLYSG--- 170
Cdd:PLN02600  76 SLRSTFsSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGT---QRLPRLVGRSRAkel 152
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 639234731 171 -LTGARLDGADCRFLGLADYYIESDskEDLVKALEQA 206
Cdd:PLN02600 153 iFTGRRIGAREAASMGLVNYCVPAG--EAYEKALELA 187
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
31-185 3.61e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 56.90  E-value: 3.61e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  31 IEQLGAvlkmwelSDEVVCIFLQGAGeKAFCAGGDVKKL-----HDAIVEqreidpkkVPQECLDFFSkeykvdyAIHTY 105
Cdd:PRK07938  37 ITAAGA-------DPDTRVVVLRAEG-RGFNAGVDIKELqatpgFTALID--------ANRGCFAAFR-------AVYEC 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 106 PKPVIVWGSGIVMGGGIGLmVGASHRIV-TEKSKLAMPEITIGLypdVGGTWFLNRM-PSAYGLYSGLTGARLDGADCRF 183
Cdd:PRK07938  94 AVPVIAAVHGFCLGGGIGL-VGNADVIVaSDDATFGLPEVDRGA---LGAATHLQRLvPQHLMRALFFTAATITAAELHH 169

                 ..
gi 639234731 184 LG 185
Cdd:PRK07938 170 FG 171
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
4-206 7.04e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 56.12  E-value: 7.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKaFCAGGDVKKLHDAIVEQR------ 77
Cdd:PRK06563   1 VSRERRGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEH-FTAGLDLADVAPKLAAGGfpfpeg 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  78 EIDPKKVPQECLDffskeykvdyaihtypKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWf 157
Cdd:PRK06563  80 GIDPWGTVGRRLS----------------KPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATL- 142
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 639234731 158 lnRMPSAYG----LYSGLTGARLDGADCRFLGLADYYIESDskEDLVKALEQA 206
Cdd:PRK06563 143 --RFPQAAGwgnaMRYLLTGDEFDAQEALRLGLVQEVVPPG--EQLERAIELA 191
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
4-186 1.29e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 55.73  E-value: 1.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCA----GGDVKKLHDAIVEQREI 79
Cdd:PRK12478   7 LLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAG-RAFSGgydfGGGFQHWGEAMMTDGRW 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  80 DPKKvpqeclDFF---SKEYKVDY---AIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITI-GLYpdV 152
Cdd:PRK12478  86 DPGK------DFAmvtARETGPTQkfmAIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMwGAY--L 157
                        170       180       190
                 ....*....|....*....|....*....|....
gi 639234731 153 GGTWfLNRMPSAYGLYSGLTGARLDGADCRFLGL 186
Cdd:PRK12478 158 TGMW-LYRLSLAKVKWHSLTGRPLTGVQAAEAEL 190
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
4-161 1.59e-08

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 55.12  E-value: 1.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPM-IEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAiveQREIDPK 82
Cdd:PRK05981   6 VTLDFDGGVAILTLDHPEVMNAVSIDMlGGLAEALDAIEDGKAEVRCLVLTGAG-RGFCTGANLQGRGSG---GRESDSG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  83 KVPQECLDFFSKEYKVdyAIHTYPKPVIVWGSGIVMGGG--IGLMvgaSHRIVTEKSKLAMPEIT-IGLYPDVGGTWFLN 159
Cdd:PRK05981  82 GDAGAALETAYHPFLR--RLRNLPCPIVTAVNGPAAGVGmsFALM---GDLILCARSAYFLQAFRrIGLVPDGGSTWLLP 156

                 ..
gi 639234731 160 RM 161
Cdd:PRK05981 157 RL 158
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
7-186 4.56e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 53.82  E-value: 4.56e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   7 EIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDaivEQREIDPKKVPQ 86
Cdd:PRK06142  11 ELADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSG-KHFSYGIDLPAMAG---VFGQLGKDGLAR 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  87 ECLDFFSKEYKVDYAIHTYP---KPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGtwfLNRMPS 163
Cdd:PRK06142  87 PRTDLRREILRLQAAINAVAdcrKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGS---LQRLPR 163
                        170       180
                 ....*....|....*....|....*....
gi 639234731 164 AYGlySG------LTGARLDGADCRFLGL 186
Cdd:PRK06142 164 IIG--DGhlrelaLTGRDIDAAEAEKIGL 190
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
4-207 4.61e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 53.56  E-value: 4.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKN-KVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDaiveqreIDPK 82
Cdd:PRK06210   7 VLYEVADsGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAG-RGFCAGADMGELQT-------IDPS 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  83 KVPQEC-LDFFSKEYKVDYA--IHTYP---KPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTW 156
Cdd:PRK06210  79 DGRRDTdVRPFVGNRRPDYQtrYHFLTalrKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISW 158
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 639234731 157 FLNRMPS-AYGLYSGLTGARLDGADCRFLGLADYYIESDskEDLVKALEQAD 207
Cdd:PRK06210 159 ILPRLVGhANALDLLLSARTFYAEEALRLGLVNRVVPPD--ELMERTLAYAE 208
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
1-148 5.14e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 53.05  E-value: 5.14e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKtLNSLSLPMIEQLGAVLKMWELSDEVVCIflqgAG-EKAFCAGGDVKKLhdaiveqrei 79
Cdd:PRK06213   2 SELVSYTLEDGVATITLDDGK-VNALSPAMIDALNAALDQAEDDRAVVVI----TGqPGIFSGGFDLKVM---------- 66
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  80 dpKKVPQECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRI-VTEKSKLAMPEITIGL 148
Cdd:PRK06213  67 --TSGAQAAIALLTAGSTLARRLLSHPKPVIVACTGHAIAKGAFLLLSADYRIgVHGPFKIGLNEVAIGM 134
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
15-160 9.21e-08

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 52.55  E-value: 9.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   15 ITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKklhdaiVEQRE--IDPKKVPQ-ECLDf 91
Cdd:TIGR01929  16 ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQK------VRGDYgyIDDSGVHRlNVLD- 88
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639234731   92 fskeykVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNR 160
Cdd:TIGR01929  89 ------VQRQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMAR 151
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
1-207 1.48e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 51.91  E-value: 1.48e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVK---KLHDAIVEQR 77
Cdd:PRK08252   2 SDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAG-GTFCAGMDLKafaRGERPSIPGR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  78 ------EIDPKkvpqecldffskeykvdyaihtypKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPD 151
Cdd:PRK08252  81 gfggltERPPR------------------------KPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAA 136
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 639234731 152 VGGTWFL-NRMPSAYGLYSGLTGARLDGADCRFLGLADYYIESDskEDLVKALEQAD 207
Cdd:PRK08252 137 GGGLLRLpRRIPYHIAMELALTGDMLTAERAHELGLVNRLTEPG--QALDAALELAE 191
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
7-153 3.35e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 51.12  E-value: 3.35e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   7 EIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEkAFCAGGDVkklHDAIVEQREIDPKkvpq 86
Cdd:PRK08258  22 EVDDGVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGG-NFCSGGDV---HEIIGPLTKMDMP---- 93
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639234731  87 ECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMpeitigLYPDVG 153
Cdd:PRK08258  94 ELLAFTRMTGDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAF------LFTRVG 154
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
10-188 3.57e-07

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 52.21  E-value: 3.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  10 NKVGFITLN--SEKtLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLhdAIVEQREiDPKKVPQE 87
Cdd:PRK11154  14 DNIAVITIDvpGEK-MNTLKAEFAEQVRAILKQLREDKELKGVVFISGKPDNFIAGADINML--AACKTAQ-EAEALARQ 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  88 CLDFFSKeykvdyaIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVT--EKSKLAMPEITIGLYPDVGGTwflNRMPSAY 165
Cdd:PRK11154  90 GQQLFAE-------IEALPIPVVAAIHGACLGGGLELALACHYRVCTddPKTVLGLPEVQLGLLPGSGGT---QRLPRLI 159
                        170       180
                 ....*....|....*....|....*..
gi 639234731 166 GLYSG----LTGARLDGADCRFLGLAD 188
Cdd:PRK11154 160 GVSTAldmiLTGKQLRAKQALKLGLVD 186
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
8-190 6.09e-07

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 50.19  E-value: 6.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   8 IKNKVGFITL--NSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKLHDAIveqrEIDPkkvp 85
Cdd:PRK05674  10 IRDPRGFATLwlSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRG-RHFSAGADLAWMQQSA----DLDY---- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  86 QECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLNRMPSAY 165
Cdd:PRK05674  81 NTNLDDARELAELMYNLYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGERA 160
                        170       180
                 ....*....|....*....|....*.
gi 639234731 166 GLYSGLTGARLDGADCRFLGL-ADYY 190
Cdd:PRK05674 161 ARRYALTAERFDGRRARELGLlAESY 186
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
2-126 1.37e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 49.19  E-value: 1.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   2 DLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVKKlhDAIVEQREIDP 81
Cdd:PRK08290   4 EYVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAG-KHFSAGHDLGS--GTPGRDRDPGP 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 639234731  82 KKVPQECLDFFSK-----------EYKVDYA--IHTYPKPVIVWGSGIVMGGgiGLMV 126
Cdd:PRK08290  81 DQHPTLWWDGATKpgveqryarewEVYLGMCrrWRDLPKPTIAQVQGACIAG--GLML 136
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
45-245 3.03e-06

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 47.53  E-value: 3.03e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  45 DEVVCIFLQGaGEKAFCAGGDVKKLhDAIVEQREIDPKKVPQECLDffskeykvdyAIHTYPKPVIVWGSGIVMGGGIGL 124
Cdd:PRK05869  50 DDVAAVILYG-GHEIFSAGDDMPEL-RTLSAQEADTAARVRQQAVD----------AVAAIPKPTVAAITGYALGAGLTL 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731 125 MVGASHRIVTEKSKLAMPEITIGLYPDVGGtwfLNRMPSAYGLYSG----LTGARLDGADCRFLGLADYYIESDSKEDLV 200
Cdd:PRK05869 118 ALAADWRVSGDNVKFGATEILAGLAPSGDG---MARLTRAAGPSRAkelvFSGRFFDAEEALALGLIDEMVAPDDVYDAA 194
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 639234731 201 KAleqadWSGeryktvsevleKFSACTkmPESKAAARELFIRKFE 245
Cdd:PRK05869 195 AA-----WAR-----------RFLDGP--PHALAAAKAGISDVYE 221
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
1-67 5.45e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 47.73  E-value: 5.45e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639234731   1 MDLILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVK 67
Cdd:PRK08272   9 LKTMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAG-KGFCAGYDLS 74
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
4-121 7.58e-06

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 46.81  E-value: 7.58e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGEKAFCAGGDVKKLHDAiveqREIDPKK 83
Cdd:PRK07396  15 ILYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRGYG----GYVDDDG 90
                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 639234731  84 VPQ-ECLDFfskeykvDYAIHTYPKPVIVWGSGIVMGGG 121
Cdd:PRK07396  91 VPRlNVLDL-------QRLIRTCPKPVIAMVAGYAIGGG 122
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
12-187 7.93e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 46.56  E-value: 7.93e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  12 VGFITLNSEKTLNSLSLPMIEQLG-AVLKMweLSDEVVCIFLQGAGeKAFCAGGDvkkLHDAIVEQreidpkkvpqeclD 90
Cdd:PRK07854  10 VLTIELQRPERRNALNAELCEELReAVRKA--VDESARAIVLTGQG-TVFCAGAD---LSGDVYAD-------------D 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  91 FFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDvggTWFLNRMPS--AYGLY 168
Cdd:PRK07854  71 FPDALIEMLHAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALD---NWTIRRLSSlvGGGRA 147
                        170       180
                 ....*....|....*....|.
gi 639234731 169 SG--LTGARLDGADCRFLGLA 187
Cdd:PRK07854 148 RAmlLGAEKLTAEQALATGMA 168
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
5-212 8.48e-06

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 47.55  E-value: 8.48e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   5 LTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEvvcifLQGA----GEKAFCAGGDVKKLHDAIveqreid 80
Cdd:PRK11730  10 VDWLEDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSD-----LKGLlltsAKDAFIVGADITEFLSLF------- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  81 pkKVPQECL-DFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTwflN 159
Cdd:PRK11730  78 --AAPEEELsQWLHFANSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGT---V 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639234731 160 RMPSAYGLYSGL----TGARLDGADCRFLGLADYYIESDS-KEDLVKALEQA-----DWSGER 212
Cdd:PRK11730 153 RLPRLIGADNALewiaAGKDVRAEDALKVGAVDAVVAPEKlQEAALALLKQAiagklDWKARR 215
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
4-150 4.57e-05

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 44.29  E-value: 4.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   4 ILTEIKNKVGFITLNSEKTLNSLSLPMIEQLGAVLKmwELSDEVVCIFLQGAGEkAFCAGGDVKKLHdaiveQREIDPKK 83
Cdd:PRK07112   6 IRVRQQGDVCFLQLHRPEAQNTINDRLIAECMDVLD--RCEHAATIVVLEGLPE-VFCFGADFSAIA-----EKPDAGRA 77
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639234731  84 VPqecldfFSKE--YKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYP 150
Cdd:PRK07112  78 DL------IDAEplYDLWHRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP 140
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
1-195 6.22e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 44.05  E-value: 6.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731   1 MDLILTEI-KNKVGFITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDvkklHDAIVEQREI 79
Cdd:PRK05864   8 MSLVLVDHpRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAG-RGFSSGAD----HKSAGVVPHV 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  80 DPKKVPQECLDFFSKEYKVDYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKLAMPEITIGLYPDVGGTWFLn 159
Cdd:PRK05864  83 EGLTRPTYALRSMELLDDVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTASELGLSYL- 161
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 639234731 160 rMPSAYGLYSG----LTGARLDGADCRFLGLADYYIESDS 195
Cdd:PRK05864 162 -LPRAIGSSRAfeimLTGRDVDAEEAERIGLVSRQVPDEQ 200
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
15-139 5.37e-03

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 38.08  E-value: 5.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639234731  15 ITLNSEKTLNSLSLPMIEQLGAVLKMWELSDEVVCIFLQGAGeKAFCAGGDVkklhdAIVEQREIDPK---KVPQECLDF 91
Cdd:PRK07327  25 IVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEG-KAFSAGGDL-----ALVEEMADDFEvraRVWREARDL 98
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 639234731  92 FskeykvdYAIHTYPKPVIVWGSGIVMGGGIGLMVGASHRIVTEKSKL 139
Cdd:PRK07327  99 V-------YNVINCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARI 139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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