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Conserved domains on  [gi|639241821|ref|WP_024572102|]
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MULTISPECIES: ferredoxin--NADP(+) reductase [Bacillus]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11422994)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.50.50.60
EC:  1.-.-.-
Gene Ontology:  GO:0050660|GO:0016491
PubMed:  33684359

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
8-319 2.62e-99

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 295.11  E-value: 2.62e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   8 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFlPKLGGKVSLFfpeKIIRDIGGIP-GIAGKQLIEQLKEQAATFDPDIVM 86
Cdd:COG0492    1 YDVVIIGAGPAGLTAAIYAARAGLKTLVIEG-GEPGGQLATT---KEIENYPGFPeGISGPELAERLREQAERFGAEILL 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  87 nQRVTGFERlDDGIIVLTGSEGEKHYTRTVILACGMG--TLEVnefdsEDAARYAGKNLHYGVeKLDA--FKGKHVVISG 162
Cdd:COG0492   77 -EEVTSVDK-DDGPFRVTTDDGTEYEAKAVIIATGAGprKLGL-----PGEEEFEGRGVSYCA-TCDGffFRGKDVVVVG 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 163 GGDTAVDWANELEPIAASVTVVHRRQEFGGMESSVTKMKQSS-VRVLTPYCLERLSGDeERIKSVTICHTESGQREDIEV 241
Cdd:COG0492  149 GGDSALEEALYLTKFASKVTLIHRRDELRASKILVERLRANPkIEVLWNTEVTEIEGD-GRVEGVTLKNVKTGEEKELEV 227
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639241821 242 DELIINHGFKIDLGPMMEWGLEI-EEGRVKADRHMRTNLPGVFVAGDAAFYesKLRLIAGGFTEGPTAVNSAKAYLDPK 319
Cdd:COG0492  228 DGVFVAIGLKPNTELLKGLGLELdEDGYIVVDEDMETSVPGVFAAGDVRDY--KYRQAATAAGEGAIAALSAARYLEPL 304
 
Name Accession Description Interval E-value
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
8-319 2.62e-99

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 295.11  E-value: 2.62e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   8 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFlPKLGGKVSLFfpeKIIRDIGGIP-GIAGKQLIEQLKEQAATFDPDIVM 86
Cdd:COG0492    1 YDVVIIGAGPAGLTAAIYAARAGLKTLVIEG-GEPGGQLATT---KEIENYPGFPeGISGPELAERLREQAERFGAEILL 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  87 nQRVTGFERlDDGIIVLTGSEGEKHYTRTVILACGMG--TLEVnefdsEDAARYAGKNLHYGVeKLDA--FKGKHVVISG 162
Cdd:COG0492   77 -EEVTSVDK-DDGPFRVTTDDGTEYEAKAVIIATGAGprKLGL-----PGEEEFEGRGVSYCA-TCDGffFRGKDVVVVG 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 163 GGDTAVDWANELEPIAASVTVVHRRQEFGGMESSVTKMKQSS-VRVLTPYCLERLSGDeERIKSVTICHTESGQREDIEV 241
Cdd:COG0492  149 GGDSALEEALYLTKFASKVTLIHRRDELRASKILVERLRANPkIEVLWNTEVTEIEGD-GRVEGVTLKNVKTGEEKELEV 227
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639241821 242 DELIINHGFKIDLGPMMEWGLEI-EEGRVKADRHMRTNLPGVFVAGDAAFYesKLRLIAGGFTEGPTAVNSAKAYLDPK 319
Cdd:COG0492  228 DGVFVAIGLKPNTELLKGLGLELdEDGYIVVDEDMETSVPGVFAAGDVRDY--KYRQAATAAGEGAIAALSAARYLEPL 304
TRX_reduct TIGR01292
thioredoxin-disulfide reductase; This model describes thioredoxin-disulfide reductase, a ...
9-316 2.50e-39

thioredoxin-disulfide reductase; This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport]


Pssm-ID: 273540 [Multi-domain]  Cd Length: 299  Bit Score: 140.84  E-value: 2.50e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821    9 DVTIIGGGPIGLFTAFYCGMRELKTKVIEfLPKLGGKVSLffpEKIIRDIGGIP-GIAGKQLIEQLKEQAATFDPDIVMN 87
Cdd:TIGR01292   1 DVIIIGAGPAGLTAAIYAARANLKPLLIE-GMEPGGQLTT---TTEVENYPGFPeGISGPELMEKMKEQAVKFGAEIIYE 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   88 QrVTGFERLDDGIIVLTGSEGEkHYTRTVILACGMGTLEvNEFDSEDAarYAGKNLHYgVEKLDA--FKGKHVVISGGGD 165
Cdd:TIGR01292  77 E-VIKVDKSDRPFKVYTGDGKE-YTAKAVIIATGASARK-LGIPGEDE--FWGRGVSY-CATCDGpfFKNKEVAVVGGGD 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  166 TAVDWANELEPIAASVTVVHRRQEFGGMESSVTK-MKQSSVRVLTPYCLERLSGDeERIKSVTICHTESGQREDIEVDEL 244
Cdd:TIGR01292 151 SAIEEALYLTRIAKKVTLVHRRDKFRAEKILLDRlKKNPKIEFLWNSTVEEIVGD-NKVEGVKIKNTVTGEEEELEVDGV 229
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639241821  245 IINHGFKIDLGPMMEWGLEIEEGRVKADRHMRTNLPGVFVAGDAAfyESKLRLIAGGFTEGPTAVNSAKAYL 316
Cdd:TIGR01292 230 FIAIGHEPNTELLKGLLELDENGYIVTDEGMRTSVPGVFAAGDVR--DKGYRQAVTAAGDGCIAALSAERYL 299
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
8-287 3.79e-21

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 91.61  E-value: 3.79e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821    8 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFlpklgGKVSLFF---PEKIIRDIGGIPGIA--GKQLIEQLKEQAATFDP 82
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIED-----EGTCPYGgcvLSKALLGAAEAPEIAslWADLYKRKEEVVKKLNN 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   83 DI--VMNQRVTGFERlDDGIIVLTGSEGEKHYT---RTVILACGMgtlEVNEFDSEDAARYAGKNLHY--GVEKL-DAFK 154
Cdd:pfam07992  76 GIevLLGTEVVSIDP-GAKKVVLEELVDGDGETityDRLVIATGA---RPRLPPIPGVELNVGFLVRTldSAEALrLKLL 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  155 GKHVVISGGGDTAVDWANELEPIAASVTVVHRRQEFG-GMESSVTK-----MKQSSVRVLTPYCLERLSGDEERIKsvti 228
Cdd:pfam07992 152 PKRVVVVGGGYIGVELAAALAKLGKEVTLIEALDRLLrAFDEEISAalekaLEKNGVEVRLGTSVKEIIGDGDGVE---- 227
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  229 CHTESGQRedIEVDELIINHGFKIDLGPMMEWGLEIEE-GRVKADRHMRTNLPGVFVAGD 287
Cdd:pfam07992 228 VILKDGTE--IDADLVVVAIGRRPNTELLEAAGLELDErGGIVVDEYLRTSVPGIYAAGD 285
PRK15317 PRK15317
alkyl hydroperoxide reductase subunit F; Provisional
3-316 1.08e-19

alkyl hydroperoxide reductase subunit F; Provisional


Pssm-ID: 237942 [Multi-domain]  Cd Length: 517  Bit Score: 89.45  E-value: 1.08e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   3 ENQEVYDVTIIGGGPIGLFTAFYCGMRELKTKVI-EflpKLGGKVSlffpekiirDIGGI------PGIAGKQLIEQLKE 75
Cdd:PRK15317 207 NAKDPYDVLVVGGGPAGAAAAIYAARKGIRTGIVaE---RFGGQVL---------DTMGIenfisvPETEGPKLAAALEE 274
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  76 QAATFDPDIVMNQRVTGFERlDDGIIVLTGSEGEKHYTRTVILACGMGTLEVN---EfdsedaARYAGKNLHY-----Gv 147
Cdd:PRK15317 275 HVKEYDVDIMNLQRASKLEP-AAGLIEVELANGAVLKAKTVILATGARWRNMNvpgE------DEYRNKGVAYcphcdG- 346
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 148 eklDAFKGKHVVISGGGDTAVDWANELEPIAASVTVVhrrqEFGgmessvTKMKQ-----------SSVRVLTPYCLERL 216
Cdd:PRK15317 347 ---PLFKGKRVAVIGGGNSGVEAAIDLAGIVKHVTVL----EFA------PELKAdqvlqdklrslPNVTIITNAQTTEV 413
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 217 SGDEERIKSVTICHTESGQREDIEVDELIInhgfKIDLGPMMEWgLE--IE---EGRVKADRHMRTNLPGVFVAGDAAFY 291
Cdd:PRK15317 414 TGDGDKVTGLTYKDRTTGEEHHLELEGVFV----QIGLVPNTEW-LKgtVElnrRGEIIVDARGATSVPGVFAAGDCTTV 488
                        330       340
                 ....*....|....*....|....*
gi 639241821 292 ESKLRLIAGGftEGPTAVNSAKAYL 316
Cdd:PRK15317 489 PYKQIIIAMG--EGAKAALSAFDYL 511
 
Name Accession Description Interval E-value
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
8-319 2.62e-99

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 295.11  E-value: 2.62e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   8 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFlPKLGGKVSLFfpeKIIRDIGGIP-GIAGKQLIEQLKEQAATFDPDIVM 86
Cdd:COG0492    1 YDVVIIGAGPAGLTAAIYAARAGLKTLVIEG-GEPGGQLATT---KEIENYPGFPeGISGPELAERLREQAERFGAEILL 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  87 nQRVTGFERlDDGIIVLTGSEGEKHYTRTVILACGMG--TLEVnefdsEDAARYAGKNLHYGVeKLDA--FKGKHVVISG 162
Cdd:COG0492   77 -EEVTSVDK-DDGPFRVTTDDGTEYEAKAVIIATGAGprKLGL-----PGEEEFEGRGVSYCA-TCDGffFRGKDVVVVG 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 163 GGDTAVDWANELEPIAASVTVVHRRQEFGGMESSVTKMKQSS-VRVLTPYCLERLSGDeERIKSVTICHTESGQREDIEV 241
Cdd:COG0492  149 GGDSALEEALYLTKFASKVTLIHRRDELRASKILVERLRANPkIEVLWNTEVTEIEGD-GRVEGVTLKNVKTGEEKELEV 227
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639241821 242 DELIINHGFKIDLGPMMEWGLEI-EEGRVKADRHMRTNLPGVFVAGDAAFYesKLRLIAGGFTEGPTAVNSAKAYLDPK 319
Cdd:COG0492  228 DGVFVAIGLKPNTELLKGLGLELdEDGYIVVDEDMETSVPGVFAAGDVRDY--KYRQAATAAGEGAIAALSAARYLEPL 304
TRX_reduct TIGR01292
thioredoxin-disulfide reductase; This model describes thioredoxin-disulfide reductase, a ...
9-316 2.50e-39

thioredoxin-disulfide reductase; This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport]


Pssm-ID: 273540 [Multi-domain]  Cd Length: 299  Bit Score: 140.84  E-value: 2.50e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821    9 DVTIIGGGPIGLFTAFYCGMRELKTKVIEfLPKLGGKVSLffpEKIIRDIGGIP-GIAGKQLIEQLKEQAATFDPDIVMN 87
Cdd:TIGR01292   1 DVIIIGAGPAGLTAAIYAARANLKPLLIE-GMEPGGQLTT---TTEVENYPGFPeGISGPELMEKMKEQAVKFGAEIIYE 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   88 QrVTGFERLDDGIIVLTGSEGEkHYTRTVILACGMGTLEvNEFDSEDAarYAGKNLHYgVEKLDA--FKGKHVVISGGGD 165
Cdd:TIGR01292  77 E-VIKVDKSDRPFKVYTGDGKE-YTAKAVIIATGASARK-LGIPGEDE--FWGRGVSY-CATCDGpfFKNKEVAVVGGGD 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  166 TAVDWANELEPIAASVTVVHRRQEFGGMESSVTK-MKQSSVRVLTPYCLERLSGDeERIKSVTICHTESGQREDIEVDEL 244
Cdd:TIGR01292 151 SAIEEALYLTRIAKKVTLVHRRDKFRAEKILLDRlKKNPKIEFLWNSTVEEIVGD-NKVEGVKIKNTVTGEEEELEVDGV 229
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639241821  245 IINHGFKIDLGPMMEWGLEIEEGRVKADRHMRTNLPGVFVAGDAAfyESKLRLIAGGFTEGPTAVNSAKAYL 316
Cdd:TIGR01292 230 FIAIGHEPNTELLKGLLELDENGYIVTDEGMRTSVPGVFAAGDVR--DKGYRQAVTAAGDGCIAALSAERYL 299
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
8-287 3.79e-21

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 91.61  E-value: 3.79e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821    8 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFlpklgGKVSLFF---PEKIIRDIGGIPGIA--GKQLIEQLKEQAATFDP 82
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIED-----EGTCPYGgcvLSKALLGAAEAPEIAslWADLYKRKEEVVKKLNN 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   83 DI--VMNQRVTGFERlDDGIIVLTGSEGEKHYT---RTVILACGMgtlEVNEFDSEDAARYAGKNLHY--GVEKL-DAFK 154
Cdd:pfam07992  76 GIevLLGTEVVSIDP-GAKKVVLEELVDGDGETityDRLVIATGA---RPRLPPIPGVELNVGFLVRTldSAEALrLKLL 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  155 GKHVVISGGGDTAVDWANELEPIAASVTVVHRRQEFG-GMESSVTK-----MKQSSVRVLTPYCLERLSGDEERIKsvti 228
Cdd:pfam07992 152 PKRVVVVGGGYIGVELAAALAKLGKEVTLIEALDRLLrAFDEEISAalekaLEKNGVEVRLGTSVKEIIGDGDGVE---- 227
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  229 CHTESGQRedIEVDELIINHGFKIDLGPMMEWGLEIEE-GRVKADRHMRTNLPGVFVAGD 287
Cdd:pfam07992 228 VILKDGTE--IDADLVVVAIGRRPNTELLEAAGLELDErGGIVVDEYLRTSVPGIYAAGD 285
PRK15317 PRK15317
alkyl hydroperoxide reductase subunit F; Provisional
3-316 1.08e-19

alkyl hydroperoxide reductase subunit F; Provisional


Pssm-ID: 237942 [Multi-domain]  Cd Length: 517  Bit Score: 89.45  E-value: 1.08e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   3 ENQEVYDVTIIGGGPIGLFTAFYCGMRELKTKVI-EflpKLGGKVSlffpekiirDIGGI------PGIAGKQLIEQLKE 75
Cdd:PRK15317 207 NAKDPYDVLVVGGGPAGAAAAIYAARKGIRTGIVaE---RFGGQVL---------DTMGIenfisvPETEGPKLAAALEE 274
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  76 QAATFDPDIVMNQRVTGFERlDDGIIVLTGSEGEKHYTRTVILACGMGTLEVN---EfdsedaARYAGKNLHY-----Gv 147
Cdd:PRK15317 275 HVKEYDVDIMNLQRASKLEP-AAGLIEVELANGAVLKAKTVILATGARWRNMNvpgE------DEYRNKGVAYcphcdG- 346
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 148 eklDAFKGKHVVISGGGDTAVDWANELEPIAASVTVVhrrqEFGgmessvTKMKQ-----------SSVRVLTPYCLERL 216
Cdd:PRK15317 347 ---PLFKGKRVAVIGGGNSGVEAAIDLAGIVKHVTVL----EFA------PELKAdqvlqdklrslPNVTIITNAQTTEV 413
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 217 SGDEERIKSVTICHTESGQREDIEVDELIInhgfKIDLGPMMEWgLE--IE---EGRVKADRHMRTNLPGVFVAGDAAFY 291
Cdd:PRK15317 414 TGDGDKVTGLTYKDRTTGEEHHLELEGVFV----QIGLVPNTEW-LKgtVElnrRGEIIVDARGATSVPGVFAAGDCTTV 488
                        330       340
                 ....*....|....*....|....*
gi 639241821 292 ESKLRLIAGGftEGPTAVNSAKAYL 316
Cdd:PRK15317 489 PYKQIIIAMG--EGAKAALSAFDYL 511
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
64-286 5.86e-18

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 82.66  E-value: 5.86e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   64 IAGKQLIEQLKEQAATFDPDIVMNQRVTGFERLDDGIIVLTgsEGEKHYTRTVILACGmgtlevnEFDSEDAARYAGKNL 143
Cdd:pfam13738  72 PSGNEYAEYLRRVADHFELPINLFEEVTSVKKEDDGFVVTT--SKGTYQARYVIIATG-------EFDFPNKLGVPELPK 142
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  144 HYG-VEKLDAFKGKHVVISGGGDTAVDWANELEPIAASVTVVHRRQEFGGMESSVtkmkqsSVRvLTPYCLERLSG--DE 220
Cdd:pfam13738 143 HYSyVKDFHPYAGQKVVVIGGYNSAVDAALELVRKGARVTVLYRGSEWEDRDSDP------SYS-LSPDTLNRLEElvKN 215
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  221 ERIK----SVTICHTESGQREDIEVDE---LIINH------GFKIDLGPMMEWGLEIEE-GRVKADRH-MRTNLPGVFVA 285
Cdd:pfam13738 216 GKIKahfnAEVKEITEVDVSYKVHTEDgrkVTSNDdpilatGYHPDLSFLKKGLFELDEdGRPVLTEEtESTNVPGLFLA 295

                  .
gi 639241821  286 G 286
Cdd:pfam13738 296 G 296
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
10-293 1.84e-16

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 79.79  E-value: 1.84e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  10 VTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVSLFFPE-KIIRDIggipgIAgkQLIEQLKEQAATFdpdiVMNQ 88
Cdd:COG0493  124 VAVVGSGPAGLAAAYQLARAGHEVTVFEALDKPGGLLRYGIPEfRLPKDV-----LD--REIELIEALGVEF----RTNV 192
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  89 RVTG---FERLddgiivltgsegEKHYTRtVILACGMGT---LEVnefDSEDAaryagKNLHYGVEKLDAF--------- 153
Cdd:COG0493  193 EVGKditLDEL------------LEEFDA-VFLATGAGKprdLGI---PGEDL-----KGVHSAMDFLTAVnlgeapdti 251
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 154 --KGKHVVISGGGDTAVD---WANELEpiAASVTVVHRRQEfggmessvTKMKQSSVRV-------------LTPyclER 215
Cdd:COG0493  252 laVGKRVVVIGGGNTAMDcarTALRLG--AESVTIVYRRTR--------EEMPASKEEVeealeegveflflVAP---VE 318
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 216 LSGDEE-RIKSVTICHTE------SGQR---------EDIEVDELIINHGFKIDLGPMME-WGLEIEE-GRVKAD-RHMR 276
Cdd:COG0493  319 IIGDENgRVTGLECVRMElgepdeSGRRrpvpiegseFTLPADLVILAIGQTPDPSGLEEeLGLELDKrGTIVVDeETYQ 398
                        330
                 ....*....|....*..
gi 639241821 277 TNLPGVFVAGDAAFYES 293
Cdd:COG0493  399 TSLPGVFAGGDAVRGPS 415
PRK10262 PRK10262
thioredoxin reductase; Provisional
12-321 1.26e-15

thioredoxin reductase; Provisional


Pssm-ID: 182343 [Multi-domain]  Cd Length: 321  Bit Score: 76.25  E-value: 1.26e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  12 IIGGGPIGLFTAFYCGMRELKTKVIEFLPKlGGKVSlffpekIIRDIGGIPG----IAGKQLIEQLKEQAATFDPDIVMN 87
Cdd:PRK10262  11 ILGSGPAGYTAAVYAARANLQPVLITGMEK-GGQLT------TTTEVENWPGdpndLTGPLLMERMHEHATKFETEIIFD 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  88 QrvTGFERLDDGIIVLTGSEGEkHYTRTVILACGMGTLEVNeFDSEDAARYAGKNlhyGVEKLDAF--KGKHVVISGGGD 165
Cdd:PRK10262  84 H--INKVDLQNRPFRLTGDSGE-YTCDALIIATGASARYLG-LPSEEAFKGRGVS---ACATCDGFfyRNQKVAVIGGGN 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 166 TAVDWANELEPIAASVTVVHRRQEFGG----MESSVTKMKQSSVRVLTPYCLERLSGDEERIKSVTICHTESGQR-EDIE 240
Cdd:PRK10262 157 TAVEEALYLSNIASEVHLIHRRDGFRAekilIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNiESLD 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 241 VDELIINHGFKIDLGpMMEWGLEIEEGRVKADRHM-----RTNLPGVFVAGDAAFYESKLRLIAGGftEGPTAVNSAKAY 315
Cdd:PRK10262 237 VAGLFVAIGHSPNTA-IFEGQLELENGYIKVQSGIhgnatQTSIPGVFAAGDVMDHIYRQAITSAG--TGCMAALDAERY 313

                 ....*.
gi 639241821 316 LDPKAE 321
Cdd:PRK10262 314 LDGLAD 319
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
10-289 3.43e-14

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 72.90  E-value: 3.43e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  10 VTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGkVSLFfpekiirdigGIPG------IAgKQLIEQLKEQAATFDPD 83
Cdd:PRK11749 143 VAVIGAGPAGLTAAHRLARKGYDVTIFEARDKAGG-LLRY----------GIPEfrlpkdIV-DREVERLLKLGVEIRTN 210
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  84 IVMNQRVTgFERLDDGiivltgsegekhYtRTVILACGMG---TLEVnefDSEDAAryagkNLHYGVE----------KL 150
Cdd:PRK11749 211 TEVGRDIT-LDELRAG------------Y-DAVFIGTGAGlprFLGI---PGENLG-----GVYSAVDfltrvnqavaDY 268
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 151 DAFKGKHVVISGGGDTAVDWANELepI---AASVTVVHRR--QEFGGMESSVTKMKQSSVRVLTPYCLERLSGDEERIKS 225
Cdd:PRK11749 269 DLPVGKRVVVIGGGNTAMDAARTA--KrlgAESVTIVYRRgrEEMPASEEEVEHAKEEGVEFEWLAAPVEILGDEGRVTG 346
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 226 VTICHTESGQRED--------------IEVDELIINHGFKIDLgPMMEW--GLEIEE--GRVKADRHMRTNLPGVFVAGD 287
Cdd:PRK11749 347 VEFVRMELGEPDAsgrrrvpiegseftLPADLVIKAIGQTPNP-LILSTtpGLELNRwgTIIADDETGRTSLPGVFAGGD 425

                 ..
gi 639241821 288 AA 289
Cdd:PRK11749 426 IV 427
gltD PRK12810
glutamate synthase subunit beta; Reviewed
154-288 4.35e-12

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 66.73  E-value: 4.35e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 154 KGKHVVISGGGDTAVDW---ANELEpiAASVTVVH-------RRQEFGGMESSVTKMKQSSVR---VLTPYCL--ERLSG 218
Cdd:PRK12810 280 KGKHVVVIGGGDTGMDCvgtAIRQG--AKSVTQRDimpmppsRRNKNNPWPYWPMKLEVSNAHeegVEREFNVqtKEFEG 357
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 219 DEERIKSVTICHTESGQR---------EDIEVDELIINHGFkidLGPMMEW----GLEIEE-GRVKA-DRHMRTNLPGVF 283
Cdd:PRK12810 358 ENGKVTGVKVVRTELGEGdfepvegseFVLPADLVLLAMGF---TGPEAGLlaqfGVELDErGRVAApDNAYQTSNPKVF 434

                 ....*
gi 639241821 284 VAGDA 288
Cdd:PRK12810 435 AAGDM 439
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
10-289 6.82e-12

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 66.05  E-value: 6.82e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  10 VTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVsLF------FPEKII-RDIGGI--PGIagkqlieqlkeqaatf 80
Cdd:PRK12771 140 VAVIGGGPAGLSAAYHLRRMGHAVTIFEAGPKLGGMM-RYgipayrLPREVLdAEIQRIldLGV---------------- 202
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  81 dpDIVMNQRVTgferlDDgiivLTGSEGEKHYTrTVILACG--MG-TLEVnefDSEDAARY--AGKNLH-YGVEKLDaFK 154
Cdd:PRK12771 203 --EVRLGVRVG-----ED----ITLEQLEGEFD-AVFVAIGaqLGkRLPI---PGEDAAGVldAVDFLRaVGEGEPP-FL 266
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 155 GKHVVISGGGDTAVDWANELEPI-AASVTVVHRR---------QEFGGMESSVTKMK--------------QSSVRVLTP 210
Cdd:PRK12771 267 GKRVVVIGGGNTAMDAARTARRLgAEEVTIVYRRtredmpahdEEIEEALREGVEINwlrtpveiegdengATGLRVITV 346
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 211 yclERLSGDEE-RIKSVTichtesGQREDIEVDELIINHGFKIDLGPMMEW-GLEIEEGRVKADRH-MRTNLPGVFVAGD 287
Cdd:PRK12771 347 ---EKMELDEDgRPSPVT------GEEETLEADLVVLAIGQDIDSAGLESVpGVEVGRGVVQVDPNfMMTGRPGVFAGGD 417

                 ..
gi 639241821 288 AA 289
Cdd:PRK12771 418 MV 419
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
59-289 2.58e-10

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 60.60  E-value: 2.58e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  59 GGIPGIagKQLIEQLKEQAATFDPDIVMNQRVTGFERlDDGIIVLTGseGEK-HYTRtVILACGmGTLEVNEFDSEDAAR 137
Cdd:COG0446   30 GGIKDP--EDLLVRTPESFERKGIDVRTGTEVTAIDP-EAKTVTLRD--GETlSYDK-LVLATG-ARPRPPPIPGLDLPG 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 138 -YAGKNLHYGV---EKLDAFKGKHVVISGGGdtavdwanelePIA-----------ASVTVVHRRQE-FGGMESSVTK-- 199
Cdd:COG0446  103 vFTLRTLDDADalrEALKEFKGKRAVVIGGG-----------PIGlelaealrkrgLKVTLVERAPRlLGVLDPEMAAll 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 200 ---MKQSSVRVLTPYCLERLSGDEEriksVTIcHTESGqrEDIEVDELIINHGFKIDLGPMMEWGLEI-EEGRVKADRHM 275
Cdd:COG0446  172 eeeLREHGVELRLGETVVAIDGDDK----VAV-TLTDG--EEIPADLVVVAPGVRPNTELAKDAGLALgERGWIKVDETL 244
                        250
                 ....*....|....
gi 639241821 276 RTNLPGVFVAGDAA 289
Cdd:COG0446  245 QTSDPDVYAAGDCA 258
lipoamide_DH TIGR01350
dihydrolipoamide dehydrogenase; This model describes dihydrolipoamide dehydrogenase, a ...
8-288 2.65e-10

dihydrolipoamide dehydrogenase; This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.


Pssm-ID: 273568 [Multi-domain]  Cd Length: 460  Bit Score: 61.12  E-value: 2.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821    8 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEfLPKLGGkVSLffpekiirDIGGIPG---IAGKQLIEQLKEQA------- 77
Cdd:TIGR01350   2 YDVIVIGGGPGGYVAAIRAAQLGLKVALVE-KEYLGG-TCL--------NVGCIPTkalLHSAEVYDEIKHAKdlgieve 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   78 -ATFD-------PDIVMNQRVTGFERL----------------DDGIIVLTGSEGEKHYT-RTVILACGMgtlEVNEFDS 132
Cdd:TIGR01350  72 nVSVDwekmqkrKNKVVKKLVGGVSGLlkknkvtvikgeakflDPGTVSVTGENGEETLEaKNIIIATGS---RPRSLPG 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  133 EDAarYAGKNLHYGVEKLdAFKG--KHVVISGGGDTAVDWANELEPIAASVTVVhrrqEF-----GGMESSVTK-----M 200
Cdd:TIGR01350 149 PFD--FDGKVVITSTGAL-NLEEvpESLVIIGGGVIGIEFASIFASLGSKVTVI----EMldrilPGEDAEVSKvlqkaL 221
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  201 KQSSVRVLTPYCLERLSGDEERIksvtICHTESGQREDIEVDELIINHGFKIDLGP--MMEWGLEIEE-GRVKADRHMRT 277
Cdd:TIGR01350 222 KKKGVKILTNTKVTAVEKNDDQV----TYENKGGETETLTGEKVLVAVGRKPNTEGlgLEKLGVELDErGRIVVDEYMRT 297
                         330
                  ....*....|.
gi 639241821  278 NLPGVFVAGDA 288
Cdd:TIGR01350 298 NVPGIYAIGDV 308
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
8-289 3.39e-10

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 60.87  E-value: 3.39e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   8 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFlPKLGG----------KVsLFFPEKIIRDI---------GGIPGIAGKQ 68
Cdd:COG1249    4 YDLVVIGAGPGGYVAAIRAAQLGLKVALVEK-GRLGGtclnvgcipsKA-LLHAAEVAHEArhaaefgisAGAPSVDWAA 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  69 LIEQLKEQAATFDPDIVMN------QRVTGFERLDDG--IIVltgsEGEKHYT-RTVILACG--------MGTLEVNEFD 131
Cdd:COG1249   82 LMARKDKVVDRLRGGVEELlkkngvDVIRGRARFVDPhtVEV----TGGETLTaDHIVIATGsrprvppiPGLDEVRVLT 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 132 SEDAaryagknlhYGVEKLdafkGKHVVISGGGDTAVdwanELEPIAAS----VTVVHRRQEF-GGMESSVTK-----MK 201
Cdd:COG1249  158 SDEA---------LELEEL----PKSLVVIGGGYIGL----EFAQIFARlgseVTLVERGDRLlPGEDPEISEalekaLE 220
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 202 QSSVRVLTPYCLERLSGDEERIKsvtiCHTESGQRED-IEVDELIINHGFK-----IDLGpmmEWGLEIEE-GRVKADRH 274
Cdd:COG1249  221 KEGIDILTGAKVTSVEKTGDGVT----VTLEDGGGEEaVEADKVLVATGRRpntdgLGLE---AAGVELDErGGIKVDEY 293
                        330
                 ....*....|....*
gi 639241821 275 MRTNLPGVFVAGDAA 289
Cdd:COG1249  294 LRTSVPGIYAIGDVT 308
PRK12770 PRK12770
putative glutamate synthase subunit beta; Provisional
10-319 1.98e-09

putative glutamate synthase subunit beta; Provisional


Pssm-ID: 237197 [Multi-domain]  Cd Length: 352  Bit Score: 58.08  E-value: 1.98e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  10 VTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVSLFFPEKIIRdiggIPGIagKQLIEQLKEQAATFDPDI----- 84
Cdd:PRK12770  21 VAIIGAGPAGLAAAGYLACLGYEVHVYDKLPEPGGLMLFGIPEFRIP----IERV--REGVKELEEAGVVFHTRTkvccg 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  85 ---------VMNQRVTGFERL---DDGIIVLTGS--------EGEKhytrtviLACGMGTLE-VNEFDsedAARYAgknl 143
Cdd:PRK12770  95 eplheeegdEFVERIVSLEELvkkYDAVLIATGTwksrklgiPGED-------LPGVYSALEyLFRIR---AAKLG---- 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 144 HYGVEKLDAFKGKHVVISGGGDTAVDWANE-LEPIAASVTVVHRR--QEFGGMESSVTKMKQSSVRVL---TPyclERLS 217
Cdd:PRK12770 161 YLPWEKVPPVEGKKVVVVGAGLTAVDAALEaVLLGAEKVYLAYRRtiNEAPAGKYEIERLIARGVEFLelvTP---VRII 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 218 GdEERIKSVTICHTE---------------SGQREDIEVDELIINHGfKIDLGPMMEWGLEIE---EGRVKADRHMRTNL 279
Cdd:PRK12770 238 G-EGRVEGVELAKMRlgepdesgrprpvpiPGSEFVLEADTVVFAIG-EIPTPPFAKECLGIElnrKGEIVVDEKHMTSR 315
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 639241821 280 PGVFVAGDAAFYESKlrlIAGGFTEGPTAVNSAKAYLDPK 319
Cdd:PRK12770 316 EGVFAAGDVVTGPSK---IGKAIKSGLRAAQSIHEWLDLK 352
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
6-187 1.29e-08

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 56.02  E-value: 1.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   6 EVYDVTIIGGGPIGLFTAFYcgmreLKTKVIEFL-----PKLGG----------------KVS--LFFPEKiirdiGGIP 62
Cdd:COG2072    5 EHVDVVVIGAGQAGLAAAYH-----LRRAGIDFVvlekaDDVGGtwrdnrypglrldtpsHLYslPFFPNW-----SDDP 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  63 GIAGKQLIEQ-LKEQAATFD--PDIVMNQRVTGFE-RLDDGIIVLTGSEGEKHYTRTVILAcgMGTLE---VNEFDSEDa 135
Cdd:COG2072   75 DFPTGDEILAyLEAYADKFGlrRPIRFGTEVTSARwDEADGRWTVTTDDGETLTARFVVVA--TGPLSrpkIPDIPGLE- 151
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 639241821 136 aRYAGKNLH-----YGVEkldaFKGKHVVISGGGDTAVDWANELEPIAASVTVVHRR 187
Cdd:COG2072  152 -DFAGEQLHsadwrNPVD----LAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRT 203
PRK12779 PRK12779
putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; ...
10-289 1.21e-07

putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; Provisional


Pssm-ID: 183740 [Multi-domain]  Cd Length: 944  Bit Score: 53.30  E-value: 1.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  10 VTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVSLFFPE-----KIIRDI-GGIPGIAGKQLIEQLKEQAATFDpd 83
Cdd:PRK12779 309 IAVVGSGPSGLINAYLLAVEGFPVTVFEAFHDLGGVLRYGIPEfrlpnQLIDDVvEKIKLLGGRFVKNFVVGKTATLE-- 386
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  84 ivmNQRVTGFERlddgIIVLTGS--------EGEkHYtrtvilacgMGTLEVNEFDSEdaaryagKNLHYGVEK-----L 150
Cdd:PRK12779 387 ---DLKAAGFWK----IFVGTGAglptfmnvPGE-HL---------LGVMSANEFLTR-------VNLMRGLDDdyetpL 442
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 151 DAFKGKHVVISGGGDTAVDWANELEPIAASVTVVHRRQEfGGMESSVTKMKQSSVRVLTpycLERLSGDEERI---KSVT 227
Cdd:PRK12779 443 PEVKGKEVFVIGGGNTAMDAARTAKRLGGNVTIVYRRTK-SEMPARVEELHHALEEGIN---LAVLRAPREFIgddHTHF 518
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 228 ICHT-----------ESGQR--------EDIEVDELIINHGFkiDLGPMM----------EWG-LEIEEGRvkadrhMRT 277
Cdd:PRK12779 519 VTHAlldvnelgepdKSGRRspkptgeiERVPVDLVIMALGN--TANPIMkdaepglktnKWGtIEVEKGS------QRT 590
                        330
                 ....*....|..
gi 639241821 278 NLPGVFVAGDAA 289
Cdd:PRK12779 591 SIKGVYSGGDAA 602
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
10-287 1.27e-07

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 53.19  E-value: 1.27e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  10 VTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGG----KVSLF-FPEKII-RDIggipgiagkqliEQLKEQAATFDPD 83
Cdd:PRK12814 196 VAIIGAGPAGLTAAYYLLRKGHDVTIFDANEQAGGmmryGIPRFrLPESVIdADI------------APLRAMGAEFRFN 263
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  84 IVMNQRVTgFERLD---DGIIVLTGSE--------GEKhyTRTVIlaCGMGTLEvnefdseDAAryAGKNLHygveklda 152
Cdd:PRK12814 264 TVFGRDIT-LEELQkefDAVLLAVGAQkaskmgipGEE--LPGVI--SGIDFLR-------NVA--LGTALH-------- 321
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 153 fKGKHVVISGGGDTAVDWA-NELEPIAASVTVVHRR--QEfggMESSVTKMKQS-----SVRVLT-PYCLERLSG----- 218
Cdd:PRK12814 322 -PGKKVVVIGGGNTAIDAArTALRLGAESVTILYRRtrEE---MPANRAEIEEAlaegvSLRELAaPVSIERSEGglelt 397
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 219 ---------DEE-RIKSVTICHTESgqreDIEVDELIINHGFKIDLGPMMEWGLEIEE-GRVKADRH-MRTNLPGVFVAG 286
Cdd:PRK12814 398 aikmqqgepDESgRRRPVPVEGSEF----TLQADTVISAIGQQVDPPIAEAAGIGTSRnGTVKVDPEtLQTSVAGVFAGG 473

                 .
gi 639241821 287 D 287
Cdd:PRK12814 474 D 474
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
8-171 2.29e-07

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 52.26  E-value: 2.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   8 YDVTIIGGGPIGLFTAFYCgMRELKTK----VIEFLPKLG------------------GKVSLFFPEKI-------IRDI 58
Cdd:COG4529    6 KRIAIIGGGASGTALAIHL-LRRAPEPlritLFEPRPELGrgvaystdspehllnvpaGRMSAFPDDPDhflrwlrENGA 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  59 GGIPGIAGKQLI----------EQLKEQAATFDPDI---VMNQRVTGFERLDDGIIVLTGSeGEKHYTRTVILACGMGTL 125
Cdd:COG4529   85 RAAPAIDPDAFVprrlfgeylrERLAEALARAPAGVrlrHIRAEVVDLERDDGGYRVTLAD-GETLRADAVVLATGHPPP 163
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 639241821 126 EVNEFDSEDAARYagknLH--YGVEKLDAFK-GKHVVISGGGDTAVDWA 171
Cdd:COG4529  164 APPPGLAAGSPRY----IAdpWPPGALARIPpDARVLIIGTGLTAIDVV 208
PRK12778 PRK12778
bifunctional dihydroorotate dehydrogenase B NAD binding subunit/NADPH-dependent glutamate ...
10-288 3.67e-07

bifunctional dihydroorotate dehydrogenase B NAD binding subunit/NADPH-dependent glutamate synthase;


Pssm-ID: 237200 [Multi-domain]  Cd Length: 752  Bit Score: 51.67  E-value: 3.67e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  10 VTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVSLFFPEkiIRdiggIPGIAGKQLIEQLKEQAATFDPDIVMNQR 89
Cdd:PRK12778 434 VAVIGSGPAGLSFAGDLAKRGYDVTVFEALHEIGGVLKYGIPE--FR----LPKKIVDVEIENLKKLGVKFETDVIVGKT 507
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  90 VT-------GFerldDGIIVLTGS--------EGEKhytrtvilacGMGTLEVNEFDSEdaaryagknlhygVEKLDAFK 154
Cdd:PRK12778 508 ITieeleeeGF----KGIFIASGAglpnfmniPGEN----------SNGVMSSNEYLTR-------------VNLMDAAS 560
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 155 ---------GKHVVISGGGDTAVDWANELEPIAA-SVTVVHRR--QEFGGMESSVTKMKQSSVRVLTPYCLERLSGDEE- 221
Cdd:PRK12778 561 pdsdtpikfGKKVAVVGGGNTAMDSARTAKRLGAeRVTIVYRRseEEMPARLEEVKHAKEEGIEFLTLHNPIEYLADEKg 640
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 222 RIKSVTICHTE------SGQR---------EDIEVDELIINHGFKID-LGPMMEWGLEI-EEGRVKADRHMRTNLPGVFV 284
Cdd:PRK12778 641 WVKQVVLQKMElgepdaSGRRrpvaipgstFTVDVDLVIVSVGVSPNpLVPSSIPGLELnRKGTIVVDEEMQSSIPGIYA 720

                 ....
gi 639241821 285 AGDA 288
Cdd:PRK12778 721 GGDI 724
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
157-227 4.79e-07

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 46.81  E-value: 4.79e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639241821  157 HVVISGGGDTAVDWANELEPIAASVTVVHRRQEFGGMESS------VTKMKQSSVRVLTPYCLERLSGDEERIKSVT 227
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARLGSKVTVVERRDRLLPGFDPeiakilQEKLEKNGIEFLLNTTVEAIEGNGDGVVVVL 77
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
10-288 1.34e-06

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 50.02  E-value: 1.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  10 VTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVSLFFPekiirdiggiPGIAGKQLIEQLKEQAATFDPDIVMNQR 89
Cdd:PRK12809 313 VAVIGAGPAGLGCADILARAGVQVDVFDRHPEIGGMLTFGIP----------PFKLDKTVLSQRREIFTAMGIDFHLNCE 382
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  90 V---TGFERLD---DGIIVLTGSEG------EKHYTRTVILACGMGTLEVNEFDS-EDAARYAgknlhygvekLDAFKGK 156
Cdd:PRK12809 383 IgrdITFSDLTseyDAVFIGVGTYGmmradlPHEDAPGVIQALPFLTAHTRQLMGlPESEEYP----------LTDVEGK 452
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 157 HVVISGGGDTAVD-WANELEPIAASVTVVHRRQEFG--GMESSVTKMKQSSVRVLTPYCLERLSGDEE-RIKSVTICHTE 232
Cdd:PRK12809 453 RVVVLGGGDTTMDcLRTSIRLNAASVTCAYRRDEVSmpGSRKEVVNAREEGVEFQFNVQPQYIACDEDgRLTAVGLIRTA 532
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639241821 233 ---------------SGQREDIEVDELIINHGFKIDLGPMME--------WGLeIEEGRvKADRHMRTNLPGVFVAGDA 288
Cdd:PRK12809 533 mgepgpdgrrrprpvAGSEFELPADVLIMAFGFQAHAMPWLQgsgikldkWGL-IQTGD-VGYLPTQTHLKKVFAGGDA 609
PRK12831 PRK12831
putative oxidoreductase; Provisional
10-288 5.20e-06

putative oxidoreductase; Provisional


Pssm-ID: 183780 [Multi-domain]  Cd Length: 464  Bit Score: 47.71  E-value: 5.20e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  10 VTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVSLFFPE------KIIrdiggipgiagKQLIEQLKEQAATFDPD 83
Cdd:PRK12831 143 VAVIGSGPAGLTCAGDLAKMGYDVTIFEALHEPGGVLVYGIPEfrlpkeTVV-----------KKEIENIKKLGVKIETN 211
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  84 IVMNQRVTGFERLD----DGIIVLTGSEGEKHYTRTVILAcgMGTLEVNEFDSEdaaryagKNLhygvekLDAFK----- 154
Cdd:PRK12831 212 VVVGKTVTIDELLEeegfDAVFIGSGAGLPKFMGIPGENL--NGVFSANEFLTR-------VNL------MKAYKpeydt 276
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 155 ----GKHVVISGGGDTAVDWANELEPIAASVTVVHRR--QEFGGMESSVTKMKQSSVRVLTPYCLERLSGDEE-RIKSVT 227
Cdd:PRK12831 277 pikvGKKVAVVGGGNVAMDAARTALRLGAEVHIVYRRseEELPARVEEVHHAKEEGVIFDLLTNPVEILGDENgWVKGMK 356
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 228 ICHTE------SGQRE---------DIEVDELIINHGfkidLGP-----MMEWGLEIEE-GRVKADRHM-RTNLPGVFVA 285
Cdd:PRK12831 357 CIKMElgepdaSGRRRpveiegsefVLEVDTVIMSLG----TSPnplisSTTKGLKINKrGCIVADEETgLTSKEGVFAG 432

                 ...
gi 639241821 286 GDA 288
Cdd:PRK12831 433 GDA 435
HI0933_like pfam03486
HI0933-like protein;
8-121 5.25e-06

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 47.58  E-value: 5.25e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821    8 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKV-----------------------------------SLFFPE 52
Cdd:pfam03486   1 FDVIVIGGGAAGLMAAISAAKRGRRVLLIEKGKKLGRKIlisgggrcnvtnlseepdnflsrypgnpkflksalSRFTPW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   53 KIIRDIG--GIPGIAG------------KQLIEQLKEQAATFDPDIVMNQRVTGFERLDDGIIVLTgSEGEKHYTRTVIL 118
Cdd:pfam03486  81 DFIAFFEslGVPLKEEdhgrlfpdsdkaSDIVDALLNELKELGVKIRLRTRVLSVEKDDDGRFRVK-TGGEELEADSLVL 159

                  ...
gi 639241821  119 ACG 121
Cdd:pfam03486 160 ATG 162
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
154-314 5.51e-06

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 47.83  E-value: 5.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 154 KGKHVVISGGGDTAVDWANELEPIAASVTVVHR------RQ---EFGGM-ESSVTKMKqssVRVLTPYCLERLSGDEeRI 223
Cdd:COG1251  141 PGKRVVVIGGGLIGLEAAAALRKRGLEVTVVERaprllpRQldeEAGALlQRLLEALG---VEVRLGTGVTEIEGDD-RV 216
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 224 KSVTichTESGQRedIEVDELIINHGFKidlgPMMEW----GLEIEEGrVKADRHMRTNLPGVFVAGDAAFYESKlrlIA 299
Cdd:COG1251  217 TGVR---LADGEE--LPADLVVVAIGVR----PNTELaraaGLAVDRG-IVVDDYLRTSDPDIYAAGDCAEHPGP---VY 283
                        170
                 ....*....|....*..
gi 639241821 300 GGFTEG--PTAVNSAKA 314
Cdd:COG1251  284 GRRVLElvAPAYEQARV 300
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
8-300 1.10e-05

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 46.71  E-value: 1.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   8 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFLPkLGG----------KVsLFFPEKIIRDI---------GGIPGIAGKQ 68
Cdd:PRK06292   4 YDVIVIGAGPAGYVAARRAAKLGKKVALIEKGP-LGGtclnvgcipsKA-LIAAAEAFHEAkhaeefgihADGPKIDFKK 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  69 LIEQLKEQAATF----------DPDIvmnQRVTGFER-LDDGIIVLtgsEGEKHYTRTVILACGMGTLEVNEFDSEDAAR 137
Cdd:PRK06292  82 VMARVRRERDRFvggvveglekKPKI---DKIKGTARfVDPNTVEV---NGERIEAKNIVIATGSRVPPIPGVWLILGDR 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 138 YAGKNlhygveklDAFK----GKHVVISGGGDTAVDWANELEPIAASVTVVHRRQEFGGMESsvTKMKQSSVRVLTPYC- 212
Cdd:PRK06292 156 LLTSD--------DAFEldklPKSLAVIGGGVIGLELGQALSRLGVKVTVFERGDRILPLED--PEVSKQAQKILSKEFk 225
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 213 -------LERLSGDEERIKSvticHTESGQREDIEVDELIINHGFK--ID-LGPMmEWGLEIEE-GRVKADRHMRTNLPG 281
Cdd:PRK06292 226 iklgakvTSVEKSGDEKVEE----LEKGGKTETIEADYVLVATGRRpnTDgLGLE-NTGIELDErGRPVVDEHTQTSVPG 300
                        330       340
                 ....*....|....*....|....*...
gi 639241821 282 VFVAGDA---------AFYESKlrlIAG 300
Cdd:PRK06292 301 IYAAGDVngkppllheAADEGR---IAA 325
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
130-292 1.42e-05

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 46.28  E-value: 1.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 130 FDSEDAARYAGKNLHYGVEKLDAFKGKHVVISGGGDTAV-------DWANELEPIA------ASVTVVHRRQEFGGM--E 194
Cdd:COG1252  124 LKTLEDALALRERLLAAFERAERRRLLTIVVVGGGPTGVelagelaELLRKLLRYPgidpdkVRITLVEAGPRILPGlgE 203
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 195 SSVTKMKQS----SVRVLTpyclerlsgdEERIKSVT--ICHTESGQRedIEVDELIINHGFKidlGP--MMEWGLEIEE 266
Cdd:COG1252  204 KLSEAAEKElekrGVEVHT----------GTRVTEVDadGVTLEDGEE--IPADTVIWAAGVK---APplLADLGLPTDR 268
                        170       180
                 ....*....|....*....|....*...
gi 639241821 267 -GRVKADRHMRT-NLPGVFVAGDAAFYE 292
Cdd:COG1252  269 rGRVLVDPTLQVpGHPNVFAIGDCAAVP 296
PTZ00058 PTZ00058
glutathione reductase; Provisional
19-288 6.18e-05

glutathione reductase; Provisional


Pssm-ID: 185420 [Multi-domain]  Cd Length: 561  Bit Score: 44.61  E-value: 6.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  19 GLFTAFYCGMRELKTKVIEFLPKLGGKVSLFFPEKIIRDIGGIPGIAGKQLIEQLKEQAATFDPDIVMNQRVTGFERLDD 98
Cdd:PTZ00058 114 GFDTQFSFNLPLLVERRDKYIRRLNDIYRQNLKKDNVEYFEGKGSLLSENQVLIKKVSQVDGEADESDDDEVTIVSAGVS 193
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  99 GIivltgSEGEKHYTRTVILACGmgtlevNEFDSEDAaryagKNLHYGVEKLDAFK---GKHVVISGGGDTAVDWANELE 175
Cdd:PTZ00058 194 QL-----DDGQVIEGKNILIAVG------NKPIFPDV-----KGKEFTISSDDFFKikeAKRIGIAGSGYIAVELINVVN 257
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 176 PIAASVTVVHRRQE-FGGMESSVT-----KMKQSSVRVLTPYCLERLSGDEEriKSVTICHTESGQreDIEVDELIINHG 249
Cdd:PTZ00058 258 RLGAESYIFARGNRlLRKFDETIInelenDMKKNNINIITHANVEEIEKVKE--KNLTIYLSDGRK--YEHFDYVIYCVG 333
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 639241821 250 FKIDLGPMMEWGLEI--EEGRVKADRHMRTNLPGVFVAGDA 288
Cdd:PTZ00058 334 RSPNTEDLNLKALNIktPKGYIKVDDNQRTSVKHIYAVGDC 374
PRK07846 PRK07846
mycothione reductase; Reviewed
156-288 9.05e-05

mycothione reductase; Reviewed


Pssm-ID: 181142 [Multi-domain]  Cd Length: 451  Bit Score: 43.79  E-value: 9.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 156 KHVVISGGGDTAVDWANELEPIAASVTVVHR-----RQEFGGMESSVTKMKQSSVRVLtpyCLERLSGDEERIKSVTIcH 230
Cdd:PRK07846 167 ESLVIVGGGFIAAEFAHVFSALGVRVTVVNRsgrllRHLDDDISERFTELASKRWDVR---LGRNVVGVSQDGSGVTL-R 242
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639241821 231 TESGqrEDIEVDELI-----INHGFKIDLGPMmewGLEI-EEGRVKADRHMRTNLPGVFVAGDA 288
Cdd:PRK07846 243 LDDG--STVEADVLLvatgrVPNGDLLDAAAA---GVDVdEDGRVVVDEYQRTSAEGVFALGDV 301
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
68-288 3.16e-04

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 42.09  E-value: 3.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   68 QLIEQLKEQAAtfDPDIVMNQRVTGFERLDDGIIVLTGSEGEKHYtRTVILACGMGTLEVNEFD---SEDAARYAgKNLH 144
Cdd:pfam01593 207 ALPDALAAQLL--GGDVRLNTRVRSIDREGDGVTVTLTDGEVIEA-DAVIVTVPLGVLKRILFTpplPPEKARAI-RNLG 282
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  145 YG-VEKL-DAFKGKHVVISGGGDTAVDWANELEPIAASVTVVHRRQEFGGMESSVTKMKQSSVRVLTPYclerlsGDEER 222
Cdd:pfam01593 283 YGpVNKVhLEFDRKFWPDLGLLGLLSELLTGLGTAFSWLTFPNRAPPGKGLLLLVYVGPGDRARELEGL------SDEEL 356
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639241821  223 IKSVTICHTESGQREDIEvDELIINHGFKIDLGPMMEWGLEIE-EGRVKADRHMRTNLPGVFVAGDA 288
Cdd:pfam01593 357 LQAVLRDLRKLFGEEAPE-PLRVLVSDWHTDPWPRGSYSLPQYgPGHDDYRPLARTPDPGLFFAGEH 422
PRK06327 PRK06327
dihydrolipoamide dehydrogenase; Validated
224-287 4.32e-04

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235779 [Multi-domain]  Cd Length: 475  Bit Score: 41.83  E-value: 4.32e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639241821 224 KSVTICHTES-GQREDIEVDELIINHGFK---IDLGPMmEWGLEIEE-GRVKADRHMRTNLPGVFVAGD 287
Cdd:PRK06327 255 KGVSVAYTDAdGEAQTLEVDKLIVSIGRVpntDGLGLE-AVGLKLDErGFIPVDDHCRTNVPNVYAIGD 322
trypano_reduc TIGR01423
trypanothione-disulfide reductase; Trypanothione, a glutathione-modified derivative of ...
156-317 5.20e-04

trypanothione-disulfide reductase; Trypanothione, a glutathione-modified derivative of spermidine, is (in its reduced form) an important antioxidant found in trypanosomatids (Crithidia, Leishmania, Trypanosoma). This model describes trypanothione reductase, a possible antitrypanosomal drug target closely related to some forms of glutathione reductase.


Pssm-ID: 200098 [Multi-domain]  Cd Length: 486  Bit Score: 41.50  E-value: 5.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  156 KHVVISGGGDTAVDWA---NELEPIAASVTVVHRRQE-FGGMESSVTK-----MKQSSVRVLTPYCLERLSGDEERIKSV 226
Cdd:TIGR01423 188 RRVLTVGGGFISVEFAgifNAYKPRGGKVTLCYRNNMiLRGFDSTLRKeltkqLRANGINIMTNENPAKVTLNADGSKHV 267
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  227 TIchtESGQREDIEVDELIINHGFKIDLGPMMEWGLEI-EEGRVKADRHMRTNLPGVFVAGDaafyesklrlIAGGFTEG 305
Cdd:TIGR01423 268 TF---ESGKTLDVDVVMMAIGRVPRTQTLQLDKVGVELtKKGAIQVDEFSRTNVPNIYAIGD----------VTDRVMLT 334
                         170
                  ....*....|..
gi 639241821  306 PTAVNSAKAYLD 317
Cdd:TIGR01423 335 PVAINEGAAFVD 346
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
8-121 3.90e-03

FAD-dependent dehydrogenase [General function prediction only];


Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 38.94  E-value: 3.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821   8 YDVTIIGGGPIGLFTAFYCGMRELKTKVIE-------------------------------------------FLPK--- 41
Cdd:COG2509   31 YDVVIVGAGPAGLFAALELAEAGLKPLVLErgkdveertcpvaefwrkgkcnpesniqfgeggagtfsdgklnTRSKdpq 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  42 -LGGKV-SLF----FPEKIIRD----IG--GIPGIAgKQLIEQLKEQAAtfdpDIVMNQRVTGFERLDDGIIVLTGSEGE 109
Cdd:COG2509  111 gLIRYVlEIFvkfgAPEEILYAakphIGtdKLPKVV-KNIREYIEELGG----EIRFNTRVTDILIEDGRVKGVVTNDGE 185
                        170
                 ....*....|..
gi 639241821 110 KHYTRTVILACG 121
Cdd:COG2509  186 EIEADAVILAPG 197
PRK06370 PRK06370
FAD-containing oxidoreductase;
156-287 4.13e-03

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 38.64  E-value: 4.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 156 KHVVISGGGDTAVDWANELEPIAASVTVVHRRQEFGGMESS-VTK-----MKQSSVRVLTPYCLERLSGDEERIksvTIC 229
Cdd:PRK06370 172 EHLVIIGGGYIGLEFAQMFRRFGSEVTVIERGPRLLPREDEdVAAavreiLEREGIDVRLNAECIRVERDGDGI---AVG 248
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639241821 230 HTESGQREDIEVDELIINHGFKI---DLGPMmEWGLEIEE-GRVKADRHMRTNLPGVFVAGD 287
Cdd:PRK06370 249 LDCNGGAPEITGSHILVAVGRVPntdDLGLE-AAGVETDArGYIKVDDQLRTTNPGIYAAGD 309
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
68-150 6.22e-03

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 38.36  E-value: 6.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821  68 QLIEQLkeqAATFDPDIVMNQRVTGFERLDDGIIVlTGSEGEKHYTRTVILACGMGTLEVNEFDSEDAARY--AGKNLHY 145
Cdd:COG1231  203 QLPRAL---AAELGDRIRLGAPVTRIRQDGDGVTV-TTDDGGTVRADAVIVTVPPSVLRRIEFDPPLPAAKraAIQRLPY 278

                 ....*.
gi 639241821 146 G-VEKL 150
Cdd:COG1231  279 GaAIKV 284
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
220-300 6.72e-03

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 38.20  E-value: 6.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639241821 220 EERIKSVTIcHTESGQRED-IEVDELII---------NHGFKidlgpmmEWGLEIEEGRVKADRHMRTNLPGVFVAGD-- 287
Cdd:PRK06416 240 EQTDDGVTV-TLEDGGKEEtLEADYVLVavgrrpnteNLGLE-------ELGVKTDRGFIEVDEQLRTNVPNIYAIGDiv 311
                         90       100
                 ....*....|....*....|..
gi 639241821 288 -------AAFYESKL--RLIAG 300
Cdd:PRK06416 312 ggpmlahKASAEGIIaaEAIAG 333
PRK08244 PRK08244
monooxygenase;
8-41 7.52e-03

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 37.80  E-value: 7.52e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 639241821   8 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFLPK 41
Cdd:PRK08244   3 YEVIIIGGGPVGLMLASELALAGVKTCVIERLKE 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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