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Conserved domains on  [gi|639299532|ref|WP_024589683|]
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MULTISPECIES: copper resistance D family protein [unclassified Pseudoalteromonas]

Protein Classification

copper resistance D family protein( domain architecture ID 10003365)

copper resistance D (CopD) family protein such as Pseudomonas fluorescens CopD, which is part of a gene cluster involved in copper resistance, together with CopR, CopS, and CopC, and is predicted to be an inner membrane protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PcoD COG1276
Putative copper export protein [Inorganic ion transport and metabolism];
89-300 3.68e-20

Putative copper export protein [Inorganic ion transport and metabolism];


:

Pssm-ID: 440887  Cd Length: 282  Bit Score: 87.81  E-value: 3.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639299532  89 MQEIVWQSVIGEQALFRGAALFVAMIValnWRINIKHRFAVVinntVMLVLLISIAYSFTFTGHSANENG--LVKSMLTF 166
Cdd:COG1276    3 LLAVLTQTSFGRAWLVRLLLAALLALL---LLLAVRSRAGAA----LLLLLALLALLTLALTGHAAASEGhaLAVLADAL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639299532 167 HLLAIASWVGSLWPLYKSCTILSVHEV-KKVMHLFGHLAIIVVFVLLISGLALLLNYLHSLSALFTSSYGQLILLKLLLV 245
Cdd:COG1276   76 HLLAAAVWVGGLLALLLLLRRLRRGAAlAAALRRFSRLALVAVALLALSGVVNAWLRLGSLSALLTTPYGRLLLAKLALV 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 639299532 246 SAMLMMGAWHKLILVPRITQ-KQHVGTLKRSISVEMLIAAFVLITTSVFTTLVGPP 300
Cdd:COG1276  156 AVLLALAALNRRRLVPRLEAgPRALRRLRRSIRAELVLGLLVLGLAAALATTPPPV 211
 
Name Accession Description Interval E-value
PcoD COG1276
Putative copper export protein [Inorganic ion transport and metabolism];
89-300 3.68e-20

Putative copper export protein [Inorganic ion transport and metabolism];


Pssm-ID: 440887  Cd Length: 282  Bit Score: 87.81  E-value: 3.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639299532  89 MQEIVWQSVIGEQALFRGAALFVAMIValnWRINIKHRFAVVinntVMLVLLISIAYSFTFTGHSANENG--LVKSMLTF 166
Cdd:COG1276    3 LLAVLTQTSFGRAWLVRLLLAALLALL---LLLAVRSRAGAA----LLLLLALLALLTLALTGHAAASEGhaLAVLADAL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639299532 167 HLLAIASWVGSLWPLYKSCTILSVHEV-KKVMHLFGHLAIIVVFVLLISGLALLLNYLHSLSALFTSSYGQLILLKLLLV 245
Cdd:COG1276   76 HLLAAAVWVGGLLALLLLLRRLRRGAAlAAALRRFSRLALVAVALLALSGVVNAWLRLGSLSALLTTPYGRLLLAKLALV 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 639299532 246 SAMLMMGAWHKLILVPRITQ-KQHVGTLKRSISVEMLIAAFVLITTSVFTTLVGPP 300
Cdd:COG1276  156 AVLLALAALNRRRLVPRLEAgPRALRRLRRSIRAELVLGLLVLGLAAALATTPPPV 211
copper_CopD NF033808
copper homeostasis membrane protein CopD; CopD is an inner membrane protein encoded in ...
 47-296 1.49e-14

copper homeostasis membrane protein CopD; CopD is an inner membrane protein encoded in Gram-negative bacterial systems that provide resistance to excess copper. It is typically chromosomal, although the PcoD protein of the plasmid-borne pco copper resistance system is a exceptional member of the CopD family.


Pssm-ID: 468191  Cd Length: 295  Bit Score: 72.54  E-value: 1.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639299532  47 SQYLKRWQIQCVALGFIAVILQVPIEAGAIAEsgvtGMLDPFmQEIVWQSV----IGEQALFRGAALFVAMIVALNWRIN 122
Cdd:NF033808  38 RRRLLRLLRLAAVLGLLSSLLWLALQAAAMGG----GWLDAL-DHTLWMVVlgtrFGQAWLWRLVALVLALLALLLLPRR 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639299532 123 iKHRFAVVINNTVMLVLLisiaysfTFTGHSANENGLVKSML----TFHLLAIASWVGSLWPL------YKSCTILSVHE 192
Cdd:NF033808 113 -PRRLLLALLGAVALATL-------AWTGHAAMDEGLLGVLHllndILHLLAAGAWLGALLPLllllrrARLGRDAWRRL 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639299532 193 VKKVMHLF---GHLAIIVVFVLLISglalllNYL-----HSLSALFTSSYGQLILLKLLLVSAMLMMGAWHKLILVPRIT 264
Cdd:NF033808 185 AIRALMRFsrvGHLAVALLIVTGVV------NYLlivgpWPLDWLSSSTYGRLLLLKLALVALMLGLALANRYRLVPRLE 258

                        250       260       270
                 ....*....|....*....|....*....|....
gi 639299532 265 Q--KQHVGTLKRSISVEMLIAAFVLITTSVFTTL 296
Cdd:NF033808 259 RalRGALRALRRSTALELALGVLVLALVAWLGTL 292
CopD pfam05425
Copper resistance protein D; Copper sequestering activity displayed by some bacteria is ...
 225-293 9.85e-05

Copper resistance protein D; Copper sequestering activity displayed by some bacteria is determined by copper-binding protein products of the copper resistance operon (cop). CopD, together with CopC, perform copper uptake into the cytoplasm.


Pssm-ID: 428466 [Multi-domain]  Cd Length: 96  Bit Score: 40.68  E-value: 9.85e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639299532  225 SLSALFTSSYGQLILLKLLLVSAMLMMGAWHKLILVPRITQKQH-----VGTLKRSISVEMLIAAFVLITTSVF 293
Cdd:pfam05425  23 GLGGLLTTAYGQLLLAKLALVLLLLALAALNRFRLVPRLRARGAggralRRRLRRSVRLELVLGLVVLGLAAVL 96
 
Name Accession Description Interval E-value
PcoD COG1276
Putative copper export protein [Inorganic ion transport and metabolism];
89-300 3.68e-20

Putative copper export protein [Inorganic ion transport and metabolism];


Pssm-ID: 440887  Cd Length: 282  Bit Score: 87.81  E-value: 3.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639299532  89 MQEIVWQSVIGEQALFRGAALFVAMIValnWRINIKHRFAVVinntVMLVLLISIAYSFTFTGHSANENG--LVKSMLTF 166
Cdd:COG1276    3 LLAVLTQTSFGRAWLVRLLLAALLALL---LLLAVRSRAGAA----LLLLLALLALLTLALTGHAAASEGhaLAVLADAL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639299532 167 HLLAIASWVGSLWPLYKSCTILSVHEV-KKVMHLFGHLAIIVVFVLLISGLALLLNYLHSLSALFTSSYGQLILLKLLLV 245
Cdd:COG1276   76 HLLAAAVWVGGLLALLLLLRRLRRGAAlAAALRRFSRLALVAVALLALSGVVNAWLRLGSLSALLTTPYGRLLLAKLALV 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 639299532 246 SAMLMMGAWHKLILVPRITQ-KQHVGTLKRSISVEMLIAAFVLITTSVFTTLVGPP 300
Cdd:COG1276  156 AVLLALAALNRRRLVPRLEAgPRALRRLRRSIRAELVLGLLVLGLAAALATTPPPV 211
copper_CopD NF033808
copper homeostasis membrane protein CopD; CopD is an inner membrane protein encoded in ...
 47-296 1.49e-14

copper homeostasis membrane protein CopD; CopD is an inner membrane protein encoded in Gram-negative bacterial systems that provide resistance to excess copper. It is typically chromosomal, although the PcoD protein of the plasmid-borne pco copper resistance system is a exceptional member of the CopD family.


Pssm-ID: 468191  Cd Length: 295  Bit Score: 72.54  E-value: 1.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639299532  47 SQYLKRWQIQCVALGFIAVILQVPIEAGAIAEsgvtGMLDPFmQEIVWQSV----IGEQALFRGAALFVAMIVALNWRIN 122
Cdd:NF033808  38 RRRLLRLLRLAAVLGLLSSLLWLALQAAAMGG----GWLDAL-DHTLWMVVlgtrFGQAWLWRLVALVLALLALLLLPRR 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639299532 123 iKHRFAVVINNTVMLVLLisiaysfTFTGHSANENGLVKSML----TFHLLAIASWVGSLWPL------YKSCTILSVHE 192
Cdd:NF033808 113 -PRRLLLALLGAVALATL-------AWTGHAAMDEGLLGVLHllndILHLLAAGAWLGALLPLllllrrARLGRDAWRRL 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639299532 193 VKKVMHLF---GHLAIIVVFVLLISglalllNYL-----HSLSALFTSSYGQLILLKLLLVSAMLMMGAWHKLILVPRIT 264
Cdd:NF033808 185 AIRALMRFsrvGHLAVALLIVTGVV------NYLlivgpWPLDWLSSSTYGRLLLLKLALVALMLGLALANRYRLVPRLE 258

                        250       260       270
                 ....*....|....*....|....*....|....
gi 639299532 265 Q--KQHVGTLKRSISVEMLIAAFVLITTSVFTTL 296
Cdd:NF033808 259 RalRGALRALRRSTALELALGVLVLALVAWLGTL 292
CopD pfam05425
Copper resistance protein D; Copper sequestering activity displayed by some bacteria is ...
 225-293 9.85e-05

Copper resistance protein D; Copper sequestering activity displayed by some bacteria is determined by copper-binding protein products of the copper resistance operon (cop). CopD, together with CopC, perform copper uptake into the cytoplasm.


Pssm-ID: 428466 [Multi-domain]  Cd Length: 96  Bit Score: 40.68  E-value: 9.85e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639299532  225 SLSALFTSSYGQLILLKLLLVSAMLMMGAWHKLILVPRITQKQH-----VGTLKRSISVEMLIAAFVLITTSVF 293
Cdd:pfam05425  23 GLGGLLTTAYGQLLLAKLALVLLLLALAALNRFRLVPRLRARGAggralRRRLRRSVRLELVLGLVVLGLAAVL 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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