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Conserved domains on  [gi|639301491|ref|WP_024590369|]
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MULTISPECIES: DNA polymerase III subunit [Pseudoalteromonas]

Protein Classification

DNA polymerase III subunit( domain architecture ID 11489505)

DNA polymerase III subunit such as delta, delta', gamma, and tau, is part of the clamp-loading complex, which assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 11-188 7.20e-57

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 181.67  E-value: 7.20e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   11 ARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlKPCGHCKSCLLTLAGTHPDKRLTQVDG 90
Cdd:TIGR00678   2 QQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGG--------EPCGECHSCRLIEAGNHPDLHRLEPEG 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   91 QSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK 170
Cdd:TIGR00678  74 QSIKVDQVRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFP 153

                         170
                  ....*....|....*...
gi 639301491  171 ITNTALAQQWLETLDIPN 188
Cdd:TIGR00678 154 PLSEEALLQWLIRQGISE 171
 
Name Accession Description Interval E-value
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 11-188 7.20e-57

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 181.67  E-value: 7.20e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   11 ARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlKPCGHCKSCLLTLAGTHPDKRLTQVDG 90
Cdd:TIGR00678   2 QQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGG--------EPCGECHSCRLIEAGNHPDLHRLEPEG 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   91 QSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK 170
Cdd:TIGR00678  74 QSIKVDQVRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFP 153

                         170
                  ....*....|....*...
gi 639301491  171 ITNTALAQQWLETLDIPN 188
Cdd:TIGR00678 154 PLSEEALLQWLIRQGISE 171
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
6-274 5.41e-56

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 182.87  E-value: 5.41e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   6 LHDTQARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlKPCGHCKScLLTLAGTHPDKRL 85
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGG--------KACGQCHS-RLMAAGNHPDLLE 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  86 --TQVDGQSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSR 163
Cdd:COG0470   72 lnPEEKSDQIGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSR 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491 164 CAKSDVKITNTALAQQWLETLDIPN---YSWLALFYNQPLQVKHWQQQDQLKniDTLYKFATEFKQSHNFKALVDIINKQ 240
Cdd:COG0470  152 CQVIRFRPPSEEEALAWLREEGVDEdalEAILRLAGGDPRAAINLLQALAGR--KELLEDLAALLSRDRALELLDALLKA 229

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 639301491 241 PELVRI--FTLFLSVQLKQQLLQGMSFDAYQSAQNA 274
Cdd:COG0470  230 EALELLdwLLKWLLDNLPLEYAGEDLARAYEALSEA 265
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
 4-211 9.70e-47

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 159.90  E-value: 9.70e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   4 PWLHDTQARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQniakqvaaQNSMLKPCGHCKSCLLTLAGTHPD- 82
Cdd:PRK06871   5 PWLQPTYQQITQAFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQ--------TPQGDQPCGQCHSCHLFQAGNHPDf 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  83 KRLTQVDGQSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILS 162
Cdd:PRK06871  77 HILEPIDNKDIGVDQVREINEKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYS 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 639301491 163 RCAKSDVKITNTALAQQWL------ETLDIpnYSWLALFYNQPLQVKHWQQQDQL 211
Cdd:PRK06871 157 RCQTWLIHPPEEQQALDWLqaqssaEISEI--LTALRINYGRPLLALTFLEQGLL 209
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
 12-164 1.64e-45

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 151.59  E-value: 1.64e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   12 RLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlKPCGHCKSCLLTLAGTHPDKRLTQVDGQ 91
Cdd:pfam13177   8 LLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDD--------LPCGQCRSCRRIESGNHPDLVIIEPEGQ 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639301491   92 SIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:pfam13177  80 SIKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRC 152
 
Name Accession Description Interval E-value
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 11-188 7.20e-57

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 181.67  E-value: 7.20e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   11 ARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlKPCGHCKSCLLTLAGTHPDKRLTQVDG 90
Cdd:TIGR00678   2 QQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGG--------EPCGECHSCRLIEAGNHPDLHRLEPEG 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   91 QSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK 170
Cdd:TIGR00678  74 QSIKVDQVRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFP 153

                         170
                  ....*....|....*...
gi 639301491  171 ITNTALAQQWLETLDIPN 188
Cdd:TIGR00678 154 PLSEEALLQWLIRQGISE 171
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
6-274 5.41e-56

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 182.87  E-value: 5.41e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   6 LHDTQARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlKPCGHCKScLLTLAGTHPDKRL 85
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGG--------KACGQCHS-RLMAAGNHPDLLE 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  86 --TQVDGQSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSR 163
Cdd:COG0470   72 lnPEEKSDQIGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSR 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491 164 CAKSDVKITNTALAQQWLETLDIPN---YSWLALFYNQPLQVKHWQQQDQLKniDTLYKFATEFKQSHNFKALVDIINKQ 240
Cdd:COG0470  152 CQVIRFRPPSEEEALAWLREEGVDEdalEAILRLAGGDPRAAINLLQALAGR--KELLEDLAALLSRDRALELLDALLKA 229

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 639301491 241 PELVRI--FTLFLSVQLKQQLLQGMSFDAYQSAQNA 274
Cdd:COG0470  230 EALELLdwLLKWLLDNLPLEYAGEDLARAYEALSEA 265
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
13-164 4.14e-47

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 161.13  E-value: 4.14e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNiakqvaaqNSMLKPCGHCKSCLLTLAGTHPDkrLTQVD--G 90
Cdd:COG2812   22 LKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCEN--------GPTGEPCGECESCRAIAAGSHPD--VIEIDaeA 91

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639301491  91 QSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:COG2812   92 SNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRC 165
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
 4-211 9.70e-47

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 159.90  E-value: 9.70e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   4 PWLHDTQARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQniakqvaaQNSMLKPCGHCKSCLLTLAGTHPD- 82
Cdd:PRK06871   5 PWLQPTYQQITQAFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQ--------TPQGDQPCGQCHSCHLFQAGNHPDf 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  83 KRLTQVDGQSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILS 162
Cdd:PRK06871  77 HILEPIDNKDIGVDQVREINEKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYS 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 639301491 163 RCAKSDVKITNTALAQQWL------ETLDIpnYSWLALFYNQPLQVKHWQQQDQL 211
Cdd:PRK06871 157 RCQTWLIHPPEEQQALDWLqaqssaEISEI--LTALRINYGRPLLALTFLEQGLL 209
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
 1-284 4.12e-46

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 158.33  E-value: 4.12e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   1 MPLPWLHDTQARLAQSyraERFHHAQLFCGPVGVGKFELSDELGNALLCQniakqvaaQNSMLKPCGHCKSCLLTLAGTH 80
Cdd:PRK05707   3 EIYPWQQSLWQQLAGR---GRHPHAYLLHGPAGIGKRALAERLAAALLCE--------APQGGGACGSCKGCQLLRAGSH 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  81 PDK-RLTQVDG-QSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPA 158
Cdd:PRK05707  72 PDNfVLEPEEAdKTIKVDQVRELVSFVVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLP 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491 159 TILSRCAKSDVKITNTALAQQWL-----ETLDIPNYSWLALFYNQPLQVKHWQQQDQLKN----IDTLYKFAtefKQSHN 229
Cdd:PRK05707 152 TIKSRCQQQACPLPSNEESLQWLqqalpESDERERIELLTLAGGSPLRALQLHEQGVREQrarvLDGVKKLL---KQQQS 228

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 639301491 230 FKALVDIINKQP--ELVRIFTLFLSVQLKQQLLQGMSFDAYQSAQNALGEFLQNNTQ 284
Cdd:PRK05707 229 ASQLAESWLKVPllLLFDWFCDWAHDILRYQLTQDEEGLGLADMRKVLQYLAQKSPQ 285
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
 12-164 1.64e-45

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 151.59  E-value: 1.64e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   12 RLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlKPCGHCKSCLLTLAGTHPDKRLTQVDGQ 91
Cdd:pfam13177   8 LLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDD--------LPCGQCRSCRRIESGNHPDLVIIEPEGQ 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639301491   92 SIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:pfam13177  80 SIKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRC 152
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
 4-211 6.96e-37

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 134.04  E-value: 6.96e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   4 PWLHDTQARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQniakqvaaQNSMLKPCGHCKSCLLTLAGTHPD- 82
Cdd:PRK07993   5 PWLRPDYEQLVGSYQAGRGHHALLIQALPGMGDDALIYALSRWLMCQ--------QPQGHKSCGHCRGCQLMQAGTHPDy 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  83 KRLTQVDG-QSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATIL 161
Cdd:PRK07993  77 YTLTPEKGkSSLGVDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLR 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491 162 SRCAKSDVKITNTALAQQWLET-LDIPNYSWLA---------LFYNQPLQVKHWQQQDQL 211
Cdd:PRK07993 157 SRCRLHYLAPPPEQYALTWLSReVTMSQDALLAalrlsagapGAALALLQPERWQQREAL 216
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
 4-292 3.51e-32

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 121.45  E-value: 3.51e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   4 PWLHDTQARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlkPCGHCKSCLLTLAGTHPDK 83
Cdd:PRK06090   6 PWLVPVWQNWKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQNYQSE---------ACGFCHSCELMQSGNHPDL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  84 RLT--QVDGQSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATIL 161
Cdd:PRK06090  77 HVIkpEKEGKSITVEQIRQCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIV 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491 162 SRCAKSDVKITNTALAQQWL--ETLDIPNYSwLALFYNQPLQVKHWQQQDQLKNIDTLYKFATEF---KQSHNFKaLVDI 236
Cdd:PRK06090 157 SRCQQWVVTPPSTAQAMQWLkgQGITVPAYA-LKLNMGSPLKTLAMMKEGGLEKYHKLERQLVDAlsgPVSDQLK-CASL 234

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491 237 INKQPE---------LVRIFTLFLSVQLKQQL-----LQGMSFDAYQSAQNALGEFLQNNTQVLGLNLPL 292
Cdd:PRK06090 235 IAADPLthlswlwllLTDAQKVHFGVQNEYYLpgsaaLGPFTYSGLYVSTAKLERLKEQLQQFSGLNTEL 304
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
 11-164 5.06e-32

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 121.19  E-value: 5.06e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  11 ARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlKPCGHCKSCLLTLAGTHPDKRLTQVDG 90
Cdd:PRK08058  16 KMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGV--------EPCGTCTNCKRIDSGNHPDVHLVAPDG 87

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639301491  91 QSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:PRK08058  88 QSIKKDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRC 161
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
 21-178 8.71e-32

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 121.13  E-value: 8.71e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   21 RFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlKPCGHCKSCLLTLAGTHPDkrLTQVDGQS-IGVDDIR 99
Cdd:TIGR02397  34 RIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDG--------EPCNECESCKEINSGSSLD--VIEIDAASnNGVDDIR 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  100 GISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK-ITNTALAQ 178
Cdd:TIGR02397 104 EILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIPATILSRCQRFDFKrIPLEDIVE 183
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
 1-200 5.30e-30

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 116.01  E-value: 5.30e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   1 MPLPWLHDTQARLaQSYRaERFHHAQLFCGPVGVGKFELSDELGNALLCQniakqvaAQNSMLKPCGHCKSCLLTLAGTH 80
Cdd:PRK06964   1 MLYPWQTDDWNRL-QALR-ARLPHALLLHGQAGIGKLDFAQHLAQGLLCE-------TPQPDGEPCGTCAACNWFAQGNH 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  81 PDKRL----------------------------TQVDGQSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANA 132
Cdd:PRK06964  72 PDYRIvrpealaaeapgaadeakeadadeggkkTKAPSKEIKIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANA 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491 133 LLKTLEE-PTNSRFLILTTSQPAQLPaTILSRCAKSDVKITNTALAQQWLETLDIPNY-SWLALFYNQPL 200
Cdd:PRK06964 152 LLKTLEEpPPGTVFLLVSARIDRLLP-TILSRCRQFPMTVPAPEAAAAWLAAQGVADAdALLAEAGGAPL 220
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
 13-164 8.79e-29

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 114.94  E-value: 8.79e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKfelsdeLGNALLcqnIAKQVAAQNSMLKPCGHCKSCLLTLAGTHPDkrLTQVDGQS 92
Cdd:PRK14963  26 LLAALRQGRLGHAYLFSGPRGVGK------TTTARL---IAMAVNCSGEDPKPCGECESCLAVRRGAHPD--VLEIDAAS 94

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639301491  93 I-GVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:PRK14963  95 NnSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTILSRT 167
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
 11-164 2.10e-28

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 112.70  E-value: 2.10e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  11 ARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlkPCGHCKSCLLTLAGTHPDKRLTQVDG 90
Cdd:PRK07940  24 ARADVAAAGSGMTHAWLFTGPPGSGRSVAARAFAAALQCTDPDEP---------GCGECRACRTVLAGTHPDVRVVAPEG 94

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639301491  91 QSIGVDDIRGISdfmnHSAAQ---NGN-KVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:PRK07940  95 LSIGVDEVRELV----TIAARrpsTGRwRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLPTIRSRC 168
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
 13-166 6.85e-28

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 112.22  E-value: 6.85e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlKPCGHCKSCLLTLAGTHPDkrLTQVDGQS 92
Cdd:PRK14953  28 LKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEG--------EPCGKCENCVEIDKGSFPD--LIEIDAAS 97

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639301491  93 -IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAK 166
Cdd:PRK14953  98 nRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTILSRCQR 172
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
 1-166 5.13e-27

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 107.65  E-value: 5.13e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   1 MPLPWLHDTQARLAQSYraERFHHAQLFCGPVGVGKFELSDELGNALLCQniakQVAAQNsmlKPCGHCKSCLLTLAGTH 80
Cdd:PRK08699   1 MIYPWHQEQWRQIAEHW--ERRPNAWLFAGKKGIGKTAFARFAAQALLCE----TPAPGH---KPCGECMSCHLFGQGSH 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  81 PD-KRLTQVDGQ--------SIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTS 151
Cdd:PRK08699  72 PDfYEITPLSDEpengrkllQIKIDAVREIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSH 151

                        170
                 ....*....|....*
gi 639301491 152 QPAQLPATILSRCAK 166
Cdd:PRK08699 152 AADKVLPTIKSRCRK 166
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 10-168 5.89e-27

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 110.28  E-value: 5.89e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  10 QARLAQSYR----AERFHHAQLFCGPVGVGKFELSDELGNALLCQNiakqvaaQNSMLKPCGHCKSCLLTLAGTHPDkrL 85
Cdd:PRK14950  21 QEHVVQTLRnaiaEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTT-------NDPKGRPCGTCEMCRAIAEGSAVD--V 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  86 TQVDGQS-IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:PRK14950  92 IEMDAAShTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPATILSRC 171


                 ....
gi 639301491 165 AKSD 168
Cdd:PRK14950 172 QRFD 175
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 21-170 8.73e-27

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 109.83  E-value: 8.73e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  21 RFHHAQLFCGPVGVGKFELSDELGNALLCQniakqvaaQNSMLKPCGHCKSCLLTLAGTHPDkrLTQVDGQS-IGVDDIR 99
Cdd:PRK14965  36 RVAHAFLFTGARGVGKTSTARILAKALNCE--------QGLTAEPCNVCPPCVEITEGRSVD--VFEIDGASnTGVDDIR 105

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 639301491 100 GISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK 170
Cdd:PRK14965 106 ELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKVPITILSRCQRFDFR 176
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
 7-166 5.05e-26

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 105.50  E-value: 5.05e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   7 HDTQARLAQSYRAERFHHAQLFCGPVGVGKfelsdelgnALLCQNIAKQVAAQNSMLKPCGHCKSCLLTL---------- 76
Cdd:PRK07471  25 AAAEAALLDAYRSGRLHHAWLIGGPQGIGK---------ATLAYRMARFLLATPPPGGDGAVPPPTSLAIdpdhpvarri 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  77 -AGTHPD------------KRLTQVdgqsIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNS 143
Cdd:PRK07471  96 aAGAHGGlltlerswnekgKRLRTV----ITVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPAR 171

                        170       180
                 ....*....|....*....|...
gi 639301491 144 RFLILTTSQPAQLPATILSRCAK 166
Cdd:PRK07471 172 SLFLLVSHAPARLLPTIRSRCRK 194
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
 24-164 6.66e-26

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 106.77  E-value: 6.66e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  24 HAQLFCGPVGVGKFELSDELGNALLCQNiakqvaaqNSMLKPCGHCKSCLLTLAGTHPDkrLTQVDGQS-IGVDDIRGIS 102
Cdd:PRK14962  37 HAYIFAGPRGTGKTTVARILAKSLNCEN--------RKGVEPCNECRACRSIDEGTFMD--VIELDAASnRGIDEIRKIR 106

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639301491 103 DFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:PRK14962 107 DAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTIISRC 168
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 13-186 1.29e-24

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 103.63  E-value: 1.29e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNiakqvaAQNSmlKPCGHCKSCLLTLAGTHPDkrLTQVDGQS 92
Cdd:PRK08691  28 LQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCEN------AQHG--EPCGVCQSCTQIDAGRYVD--LLEIDAAS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  93 -IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK- 170
Cdd:PRK08691  98 nTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVTVLSRCLQFVLRn 177

                        170
                 ....*....|....*.
gi 639301491 171 ITNTALAQQWLETLDI 186
Cdd:PRK08691 178 MTAQQVADHLAHVLDS 193
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
 4-211 2.49e-24

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 100.42  E-value: 2.49e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   4 PWLHDTQARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIaKQVAAQnsmlkpcghcKSCLLTLAGTHPDK 83
Cdd:PRK08769   7 PWQQRAYDQTVAALDAGRLGHGLLICGPEGLGKRAVALALAEHVLASGP-DPAAAQ----------RTRQLIAAGTHPDL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  84 RLTQVDGQSIG--------VDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQ 155
Cdd:PRK08769  76 QLVSFIPNRTGdklrteivIEQVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPAR 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 639301491 156 LPATILSRCAKSDVKITNTALAQQWLETLDIPNYS---WLALFYNQPLQVKHWQQQDQL 211
Cdd:PRK08769 156 LPATIRSRCQRLEFKLPPAHEALAWLLAQGVSERAaqeALDAARGHPGLAAQWLREDGL 214
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
 13-170 1.06e-23

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 100.23  E-value: 1.06e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmLKPCGHCKSCLLTLAGTHPDkrLTQVDGQS 92
Cdd:PRK06305  29 LKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNPTED-------QEPCNQCASCKEISSGTSLD--VLEIDGAS 99

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639301491  93 -IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK 170
Cdd:PRK06305 100 hRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIPGTILSRCQKMHLK 178
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
 8-187 2.02e-23

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 98.19  E-value: 2.02e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   8 DTQARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaAQNSMLKPCGHCKSCLLTLAGTHPD----- 82
Cdd:PRK09112  30 EAEAFLAQAYREGKLHHALLFEGPEGIGKATLAFHLANHILSHPDPAE--APETLADPDPASPVWRQIAQGAHPNllhit 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  83 KRLTQVDGQ---SIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEE-PTNSRFLILTTSqPAQLPA 158
Cdd:PRK09112 108 RPFDEKTGKfktAITVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEpPARALFILISHS-SGRLLP 186

                        170       180
                 ....*....|....*....|....*....
gi 639301491 159 TILSRCAKSDVKITNTALAQQWLETLDIP 187
Cdd:PRK09112 187 TIRSRCQPISLKPLDDDELKKALSHLGSS 215
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
 13-164 2.60e-23

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 97.28  E-value: 2.60e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNiakqvaaqnsmlkPCGHCKSCLLtLAGTHPD---------- 82
Cdd:PRK07399  16 LTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGLLSQG-------------SPSKNIRRRL-EEGNHPDllwveptyqh 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  83 --KRLTQVDGQS----------IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFlILTT 150
Cdd:PRK07399  82 qgKLITASEAEEaglkrkappqIRLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANALLKTLEEPGNGTL-ILIA 160

                        170
                 ....*....|....
gi 639301491 151 SQPAQLPATILSRC 164
Cdd:PRK07399 161 PSPESLLPTIVSRC 174
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
 11-164 8.46e-23

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 98.30  E-value: 8.46e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  11 ARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNiakqvaAQNSMlkPCGHCKSCLLTLAGTHPDkrLTQVDG 90
Cdd:PRK06647  26 ETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVN------GPTPM--PCGECSSCKSIDNDNSLD--VIEIDG 95

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639301491  91 QS-IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:PRK06647  96 ASnTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATIKSRC 170
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
 13-187 1.18e-22

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 97.51  E-value: 1.18e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQniaKQVAAqnsmlKPCGHCKSCLLTLAGTHPDkrLTQVDGQS 92
Cdd:PRK14969  28 LTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCE---TGVTA-----TPCGVCSACLEIDSGRFVD--LIEVDAAS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  93 -IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK- 170
Cdd:PRK14969  98 nTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRCLQFNLKq 177

                        170       180
                 ....*....|....*....|
gi 639301491 171 ITNTALA---QQWLETLDIP 187
Cdd:PRK14969 178 MPPPLIVshlQHILEQENIP 197
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
 19-179 1.84e-22

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 97.25  E-value: 1.84e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  19 AERFHHAQLFCGPVGVGKFELSDELGNALLCQNiakQVAAQnsmlkPCGHCKSCLLTLAGTHPDkrLTQVDGQS-IGVDD 97
Cdd:PRK05563  34 QGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLN---PPDGE-----PCNECEICKAITNGSLMD--VIEIDAASnNGVDE 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  98 IRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK-ITNTAL 176
Cdd:PRK05563 104 IRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPHKIPATILSRCQRFDFKrISVEDI 183


                 ...
gi 639301491 177 AQQ 179
Cdd:PRK05563 184 VER 186
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
 13-184 2.94e-22

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 96.17  E-value: 2.94e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlKPCGHCKSCLLTLAGTHPDkrLTQVDGQS 92
Cdd:PRK14956  30 LQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGN--------EPCNECTSCLEITKGISSD--VLEIDAAS 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  93 -IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVKI 171
Cdd:PRK14956 100 nRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPETILSRCQDFIFKK 179

                        170
                 ....*....|...
gi 639301491 172 TNTALAQQWLETL 184
Cdd:PRK14956 180 VPLSVLQDYSEKL 192
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 7-164 3.07e-22

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 96.71  E-value: 3.07e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   7 HDTQArLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQ--VAAQnsmlkPCGHCKSCLLTLAGTHPDkr 84
Cdd:PRK14951  23 HVVQA-LTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCQGPDGQggITAT-----PCGVCQACRDIDSGRFVD-- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  85 LTQVDGQS-IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSR 163
Cdd:PRK14951  95 YTELDAASnRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATTDPQKVPVTVLSR 174


                 .
gi 639301491 164 C 164
Cdd:PRK14951 175 C 175
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 16-170 3.59e-22

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 96.55  E-value: 3.59e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  16 SYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQVAAQNSMLKPCGHCKSCLLTLAGTHPDkrLTQVDGQSI-G 94
Cdd:PRK14954  31 SLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDPVYLQEVTEPCGECESCRDFDAGTSLN--ISEFDAASNnS 108

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639301491  95 VDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK 170
Cdd:PRK14954 109 VDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQRFNFK 184
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
 12-164 6.05e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 93.56  E-value: 6.05e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  12 RLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQvaaqnsmlkpcghcksclltlagtHPD-KRLTQVDG 90
Cdd:PRK05564  15 RIKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIALKILGKSQQRE------------------------YVDiIEFKPINK 70

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639301491  91 QSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:PRK05564  71 KSIGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRC 144
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
20-170 1.62e-21

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 94.56  E-value: 1.62e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  20 ERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQ--VAAQnsmlkPCGHCKSCLLTLAGTHPDkrLTQVDGQS-IGVD 96
Cdd:PRK12323  35 QRLHHAYLFTGTRGVGKTTLSRILAKSLNCTGADGEggITAQ-----PCGQCRACTEIDAGRFVD--YIEMDAASnRGVD 107

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639301491  97 DIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK 170
Cdd:PRK12323 108 EMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRCLQFNLK 181
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 10-182 2.88e-21

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 93.98  E-value: 2.88e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  10 QARLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCqniakqvaAQNSMLKPCGHCKSCLLTLAGTHPDkrLTQVD 89
Cdd:PRK14959  25 KAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNC--------ETAPTGEPCNTCEQCRKVTQGMHVD--VVEID 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  90 GQS-IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAksd 168
Cdd:PRK14959  95 GASnRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHKFPVTIVSRCQ--- 171

                        170
                 ....*....|....
gi 639301491 169 vKITNTALAQQWLE 182
Cdd:PRK14959 172 -HFTFTRLSEAGLE 184
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
 21-163 1.61e-20

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 91.25  E-value: 1.61e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  21 RFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQVaaqnsmlkPCGHCKSCLLTLAGTHPDkrLTQVDGQSI-GVDDIR 99
Cdd:PRK08451  34 RLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSST--------PCDTCIQCQSALENRHID--IIEMDAASNrGIDDIR 103

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639301491 100 GISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSR 163
Cdd:PRK08451 104 ELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLPATILSR 167
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
 16-179 8.25e-20

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 88.80  E-value: 8.25e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  16 SYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQVAAQNSMLKPCGHCKSCLLTLAGTHPDkrLTQVDGQSI-G 94
Cdd:PRK14955  31 SLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDADYLQEVTEPCGECESCRDFDAGTSLN--ISEFDAASNnS 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  95 VDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK-ITN 173
Cdd:PRK14955 109 VDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQRFNFKrIPL 188


                 ....*.
gi 639301491 174 TALAQQ 179
Cdd:PRK14955 189 EEIQQQ 194
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
 20-163 1.21e-19

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 89.11  E-value: 1.21e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  20 ERFHHAQLFCGPVGVGKFELSDELGNALLCQNiakqvaaQNSMLKPCGHCKSCLltlagthpDKRL--TQVDGQS-IGVD 96
Cdd:PRK07133  37 NKISHAYLFSGPRGTGKTSVAKIFANALNCSH-------KTDLLEPCQECIENV--------NNSLdiIEMDAASnNGVD 101

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639301491  97 DIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSR 163
Cdd:PRK07133 102 EIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVHKIPLTILSR 168
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
 6-163 2.11e-19

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 86.22  E-value: 2.11e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   6 LHDTQARLAQSY----RAERFHHAQLFCGpvGVGKFELSDELGNALLCQNiakqvaAQNSMlkPCGHCKSCLLTLAGTHP 81
Cdd:PRK07276   3 LKQKQPKVFQRFqtilEQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQ------KEGVL--PCGHCRSCRLIEQGEFS 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  82 DKRLTQVDGQSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATIL 161
Cdd:PRK07276  73 DVTVIEPQGQVIKTDTIRELVKNFSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIK 152


                 ..
gi 639301491 162 SR 163
Cdd:PRK07276 153 SR 154
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
 12-170 2.98e-18

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 84.53  E-value: 2.98e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  12 RLAQSYraerfhhaqLFCGPVGVGKFELSDELGNALLCQniakQVAAQNSMLKPCGHCKSCLLTLAGTHPDkrLTQVDGQ 91
Cdd:PRK06645  41 RLAGGY---------LLTGIRGVGKTTSARIIAKAVNCS----ALITENTTIKTCEQCTNCISFNNHNHPD--IIEIDAA 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  92 S-IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK 170
Cdd:PRK06645 106 SkTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTEVQKIPATIISRCQRYDLR 185
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
21-170 3.73e-18

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 84.90  E-value: 3.73e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  21 RFHHAQLFCGPVGVGKFELSDELGNALLCQNiakQVAAQnsmlkPCGHCKSCLLTLAGTHPDkrLTQVDGQS-IGVDDIR 99
Cdd:PRK07003  36 RLHHAYLFTGTRGVGKTTLSRIFAKALNCET---GVTSQ-----PCGVCRACREIDEGRFVD--YVEMDAASnRGVDEMA 105

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 639301491 100 GISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK 170
Cdd:PRK07003 106 ALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLK 176
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
13-163 4.66e-18

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 84.16  E-value: 4.66e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCqniakqvaAQNSMLKPCGHCKSCLlTLAGTHPDK-RLTQVDGQ 91
Cdd:PRK14952  25 LSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNC--------AQGPTATPCGVCESCV-ALAPNGPGSiDVVELDAA 95

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639301491  92 SI-GVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSR 163
Cdd:PRK14952  96 SHgGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSR 168
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
 13-170 1.15e-17

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 83.21  E-value: 1.15e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNiakQVAAQnsmlkPCGHCKSCLLTLAGTHPDkrLTQVDGQS 92
Cdd:PRK14957  28 LVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKT---GVTAE-----PCNKCENCVAINNNSFID--LIEIDAAS 97

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639301491  93 -IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK 170
Cdd:PRK14957  98 rTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPVTILSRCIQLHLK 176
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
13-168 1.44e-17

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 82.70  E-value: 1.44e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQVAAqnsmlkPCGHCKSCLLTLAGTHPDkrLTQVDGQS 92
Cdd:PRK14948  28 LKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNCLNSDKPTPE------PCGKCELCRAIAAGNALD--VIEIDAAS 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  93 -IGVDDIRGI---SDFmnhSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSD 168
Cdd:PRK14948 100 nTGVDNIRELierAQF---APVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTDPQRVLPTIISRCQRFD 176
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
21-164 1.56e-17

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 82.79  E-value: 1.56e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  21 RFHHAQLFCGPVGVGKFELSDELGNALLCQNIAKQVaaqnsmlkPCGHCKSCLLTLAGTHPDkrLTQVDGQS-IGVDDIR 99
Cdd:PRK14960  35 RLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTST--------PCEVCATCKAVNEGRFID--LIEIDAASrTKVEDTR 104

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 639301491 100 GISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:PRK14960 105 ELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVISRC 169
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
 65-172 1.98e-17

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 82.14  E-value: 1.98e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  65 PCGHCKSCLLTLAGTHPDkrLTQVDGQS-IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNS 143
Cdd:PRK14964  69 PCGTCHNCISIKNSNHPD--VIEIDAASnTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPH 146

                         90       100       110
                 ....*....|....*....|....*....|
gi 639301491 144 RFLILTTSQPAQLPATILSRCAKSDV-KIT 172
Cdd:PRK14964 147 VKFILATTEVKKIPVTIISRCQRFDLqKIP 176
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 20-164 3.37e-17

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 82.08  E-value: 3.37e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  20 ERFHHAQLFCGPVGVGKFELSDELGNALLCQniaKQVAAQnsmlkPCGHCKSCLLTLAGTHPDkrLTQVDGQS-IGVDDI 98
Cdd:PRK14949  35 QRLHHAYLFTGTRGVGKTSLARLFAKGLNCE---QGVTAT-----PCGVCSSCVEIAQGRFVD--LIEVDAASrTKVDDT 104

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 639301491  99 RGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEE-PTNSRFLiLTTSQPAQLPATILSRC 164
Cdd:PRK14949 105 RELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEpPEHVKFL-LATTDPQKLPVTVLSRC 170
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
24-164 4.51e-17

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 81.36  E-value: 4.51e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  24 HAQLFCGPVGVGKFELSDELGNALLCQNIAKQVAAqnsmlkpCGHCKSCLLTlaGTHPDKRLTQVDGQSI-GVDDIRGIS 102
Cdd:PRK14971  40 HAYLFCGPRGVGKTTCARIFAKTINCQNLTADGEA-------CNECESCVAF--NEQRSYNIHELDAASNnSVDDIRNLI 110

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 639301491 103 DFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:PRK14971 111 EQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILPTILSRC 172
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
 24-184 4.94e-17

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 81.43  E-value: 4.94e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  24 HAQLFCGPVGVGKfelsdelgnallcQNIAKQVAAQNSMLKP-----CGHCKSCLLTLAGTHPDkrLTQVDGQSI-GVDD 97
Cdd:PRK05896  39 HAYIFSGPRGIGK-------------TSIAKIFAKAINCLNPkdgdcCNSCSVCESINTNQSVD--IVELDAASNnGVDE 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  98 IRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVKITNTALA 177
Cdd:PRK05896 104 IRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQKIPLTIISRCQRYNFKKLNNSEL 183


                 ....*..
gi 639301491 178 QQWLETL 184
Cdd:PRK05896 184 QELLKSI 190
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
 13-164 7.12e-17

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 80.54  E-value: 7.12e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQniaKQVAAQnsmlkPCGHCKSCLLTLAGTHPDkrLTQVDGQS 92
Cdd:PRK14958  28 LSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCE---KGVSAN-----PCNDCENCREIDEGRFPD--LFEVDAAS 97

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639301491  93 -IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:PRK14958  98 rTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPVTVLSRC 170
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
 13-173 8.20e-15

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 74.08  E-value: 8.20e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCQNiakqvaaqNSMLKPCGHCKSCLLTLAGTHPDkrLTQVDGQS 92
Cdd:PRK14961  28 ISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQN--------GITSNPCRKCIICKEIEKGLCLD--LIEIDAAS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  93 -IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVKI 171
Cdd:PRK14961  98 rTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKTILSRCLQFKLKI 177


                 ..
gi 639301491 172 TN 173
Cdd:PRK14961 178 IS 179
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
 13-164 1.89e-14

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 73.40  E-value: 1.89e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  13 LAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCqnIAKQVAAQNSMlKPCGHCKSCLLTLAGTHPDkrLTQVDGQS 92
Cdd:PRK09111  36 LTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNY--EGPDGDGGPTI-DLCGVGEHCQAIMEGRHVD--VLEMDAAS 110

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639301491  93 -IGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEE-PTNSRFLILTTsQPAQLPATILSRC 164
Cdd:PRK09111 111 hTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEpPPHVKFIFATT-EIRKVPVTVLSRC 183
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
 91-179 4.58e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 67.95  E-value: 4.58e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  91 QSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKsdVK 170
Cdd:PRK06581  67 KNISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRSRCFK--IN 144


                 ....*....
gi 639301491 171 ITNTALAQQ 179
Cdd:PRK06581 145 VRSSILHAY 153
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
 64-164 1.62e-12

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 66.01  E-value: 1.62e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  64 KPCGHCKSCLLTLAGTHPDKRLTQVDGQSIGVDDIRGISDFMNHSAAQ-NGNKVAIIENCEKMTTAAANALLKTLEEPTN 142
Cdd:PRK05818  38 GFCKTCESCLKILNGKYNDFYLIFDQKNPIKKEDALSIINKLNRPSVEsNGKKIYIIYGIEKLNKQSANSLLKLIEEPPK 117

                         90       100
                 ....*....|....*....|..
gi 639301491 143 SRFLILTTSQPAQLPATILSRC 164
Cdd:PRK05818 118 NTYGIFTTRNENNILNTILSRC 139
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 21-164 4.85e-12

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 66.43  E-value: 4.85e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  21 RFHHAQLFCGPVGVGKFELSDELGNALLCQniaKQVAAqnsmlKPCGHCKSCLLTLAGTHPDkrLTQVDGQS-IGVDDIR 99
Cdd:PRK07994  36 RLHHAYLFSGTRGVGKTTIARLLAKGLNCE---TGITA-----TPCGECDNCREIEQGRFVD--LIEIDAASrTKVEDTR 105

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639301491 100 GISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEP-TNSRFLiLTTSQPAQLPATILSRC 164
Cdd:PRK07994 106 ELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPpEHVKFL-LATTDPQKLPVTILSRC 170
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
 25-170 8.60e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 61.81  E-value: 8.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  25 AQLFCGPVGVGKFELSDELGNALLCQNIA--KQVAAQNsmlkpcghcksclltlagthpdkrLTQVDGQSI-GVDDIRGI 101
Cdd:PRK14970  41 ALLFCGPRGVGKTTCARILARKINQPGYDdpNEDFSFN------------------------IFELDAASNnSVDDIRNL 96

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639301491 102 SDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRCAKSDVK 170
Cdd:PRK14970  97 IDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIFDFK 165
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 7-163 2.64e-09

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 58.07  E-value: 2.64e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491   7 HDTQArLAQSYRAERFHHAQLFCGPVGVGKFELSDELGNALLCqniakqvaAQNSMLKPCGHCKSCLlTLAGTHP---Dk 83
Cdd:PRK07764  22 HVTEP-LSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNC--------VEGPTSTPCGECDSCV-ALAPGGPgslD- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  84 rLTQVDGQSI-GVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILS 162
Cdd:PRK07764  91 -VTEIDAASHgGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDKVIGTIRS 169


                 .
gi 639301491 163 R 163
Cdd:PRK07764 170 R 170
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
 80-164 1.09e-08

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 55.19  E-value: 1.09e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639301491  80 HPD--KRLTQVDGQSIGVDDIRGISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLP 157
Cdd:PRK05917  60 HPDihEFSPQGKGRLHSIETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLP 139


                 ....*..
gi 639301491 158 ATILSRC 164
Cdd:PRK05917 140 PTIRSRS 146
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
 101-164 3.20e-08

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 53.96  E-value: 3.20e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639301491 101 ISDFMNHSAAQNGNKVAIIENCEKMTTAAANALLKTLEEPTNSRFLILTTSQPAQLPATILSRC 164
Cdd:PRK07132  78 INKLYFSSFVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRC 141
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
 116-163 1.35e-05

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 45.02  E-value: 1.35e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 639301491 116 VAIIENCEKMTTAAANALLKTLEE-PTNSRFLILTTSQPAQLPaTILSR 163
Cdd:PRK08485  57 KIIVIAAPSYGIEAQNALLKILEEpPKNICFIIVAKSKNLLLP-TIRSR 104
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
 115-164 1.26e-03

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 39.97  E-value: 1.26e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 639301491 115 KVAIIENCEKMTTAAANALLKTLEEPTNS-RFlILTTSQPAQLPATILSRC 164
Cdd:PRK12402 127 KTILLDNAEALREDAQQALRRIMEQYSRTcRF-IIATRQPSKLIPPIRSRC 176
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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