|
Name |
Accession |
Description |
Interval |
E-value |
| PRK12282 |
PRK12282 |
tryptophanyl-tRNA synthetase II; Reviewed |
9-340 |
0e+00 |
|
tryptophanyl-tRNA synthetase II; Reviewed
Pssm-ID: 183400 [Multi-domain] Cd Length: 333 Bit Score: 614.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 9 NKDKILTGDRATGQLHLGHFVGSLQQRVALQHQYEQTILVADLQGLTDNGHNPHKVSSNILNVVADYLAVGIDTQKTTIC 88
Cdd:PRK12282 1 TKPIILTGDRPTGKLHLGHYVGSLKNRVALQNEHEQFVLIADQQALTDNAKNPEKIRRNILEVALDYLAVGIDPAKSTIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 89 LQSAIPALSELTMYYSNLVSVSRLQRNPTVKSEIASKSFGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIEQTN 168
Cdd:PRK12282 81 IQSQIPELAELTMYYMNLVTVARLERNPTVKTEIAQKGFGRSIPAGFLTYPVSQAADITAFKATLVPVGDDQLPMIEQTR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 169 EIVRKLNYIAQADILVECRPLLSKVPRLPSLDGKSKMSKSMGNSILLDSSEKDISKAVKSMYTDASHLRIEDPGKIEGNV 248
Cdd:PRK12282 161 EIVRRFNSLYGTDVLVEPEALLPEAGRLPGLDGKAKMSKSLGNAIYLSDDADTIKKKVMSMYTDPNHIRVEDPGKVEGNV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 249 VFTYLDAFHSDTAYISELKARYQQGGLGDGSLKKILEECLQDTLKPIRERRKSFISDKAQLIEILRNGSDKSQEESNQIL 328
Cdd:PRK12282 241 VFTYLDAFDPDKAEVAELKAHYQRGGLGDVKCKRYLEEVLQELLAPIRERRAEFAKDPGYVLEILKAGSEKAREVAAQTL 320
|
330
....*....|..
gi 639305404 329 NSVKNAFGLSLF 340
Cdd:PRK12282 321 SEVKDAMGLNYF 332
|
|
| TrpS |
COG0180 |
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ... |
10-340 |
3.66e-161 |
|
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439950 [Multi-domain] Cd Length: 330 Bit Score: 453.35 E-value: 3.66e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 10 KDKILTGDRATGQLHLGHFVGSLQQRVALQHQYEQTILVADLQGLTDNgHNPHKVSSNILNVVADYLAVGIDTQKTTICL 89
Cdd:COG0180 3 KKRVLSGIQPTGRLHLGNYLGALKNWVELQDEYECFFFIADLHALTTP-QDPEELRENTREVAADYLAAGLDPEKSTIFV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 90 QSAIPALSELTMYYSNLVSVSRLQRNPTVKSEIAsKSFGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIEQTNE 169
Cdd:COG0180 82 QSDVPEHAELAWLLSCLTPLGELERMPQFKDKSA-KNGKENVNAGLLTYPVLMAADILLYKADLVPVGEDQKQHLELTRD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 170 IVRKLNYIAqADILVECRPLLSK-VPRLPSLDGKSKMSKSMGNSILLDSSEKDISKAVKSMYTDASHLRIEDPGKIEGNV 248
Cdd:COG0180 161 IARRFNHRY-GEVFPEPEALIPEeGARIPGLDGRKKMSKSYGNTINLLDDPKEIRKKIKSAVTDSERLRYDDPGKPEVCN 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 249 VFTYLDAFhSDTAYISELKARYQQGGLGDGSLKKILEECLQDTLKPIRERRKSFISDKAQLIEILRNGSDKSQEESNQIL 328
Cdd:COG0180 240 LFTIYSAF-SGKEEVEELEAEYRAGGIGYGDLKKALAEAVVEFLAPIRERRAELLADPAELDEILAEGAEKARAIAAKTL 318
|
330
....*....|..
gi 639305404 329 NSVKNAFGLSLF 340
Cdd:COG0180 319 AEVREAMGLLYF 330
|
|
| TrpRS_core |
cd00806 |
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) ... |
13-289 |
7.33e-98 |
|
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. TrpRS is a homodimer which attaches Tyr to the appropriate tRNA. TrpRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding
Pssm-ID: 173903 [Multi-domain] Cd Length: 280 Bit Score: 290.64 E-value: 7.33e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 13 ILTGDRATGQLHLGHFVGSLQQRVALQH-QYEQTILVADLQGLTDNGHNPHKVSSNILNVVADYLAVGIDTQKTTICLQS 91
Cdd:cd00806 2 VLSGIQPSGSLHLGHYLGAFRFWVWLQEaGYELFFFIADLHALTVKQLDPEELRQNTRENAKDYLACGLDPEKSTIFFQS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 92 AIPALSELTMYYSNLVSVSRLQRNPTVKSEIAsksFGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIEQTNEIV 171
Cdd:cd00806 82 DVPEHYELAWLLSCVVTFGELERMTGFKDKSA---QGESVNIGLLTYPVLQAADILLYKACLVPVGIDQDPHLELTRDIA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 172 RKLNYIaQADILVECRPLLSKVPRLPSL-DGKSKMSKSMGNS-ILLDSSEKDISKAVKSMYTDASH--LRIEDPGKIEGN 247
Cdd:cd00806 159 RRFNKL-YGEIFPKPAALLSKGAFLPGLqGPSKKMSKSDPNNaIFLTDSPKEIKKKIMKAATDGGRteHRRDGGGPGVSN 237
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 639305404 248 VVFTYLDAFHSDTAYIsELKARYQQGGLGDGSLKKILEECLQ 289
Cdd:cd00806 238 LVEIYSAFFNDDDEEL-EEIDEYRSGGLGYGECKKLLAEAIQ 278
|
|
| trpS |
TIGR00233 |
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ... |
13-337 |
1.91e-78 |
|
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272975 [Multi-domain] Cd Length: 327 Bit Score: 243.01 E-value: 1.91e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 13 ILTGDRATGQLHLGHFVGSLQQRVALQHQYEQTILVADLQGLTDNGHNPHKVSSNILNVVADYLAVGIDTQKTTICLQSA 92
Cdd:TIGR00233 5 VLTGIQPSGKMHLGHYLGAIQTKWLQQFGVELFICIADLHAITVKQTDPDALRKAREELAADYLAVGLDPEKTFIFLQSD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 93 IPALSELTMYYSNLVSVSRLQRNPTVKseiaSKSFGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIEQTNEIVR 172
Cdd:TIGR00233 85 YPEHYELAWLLSCQVTFGELKRMTQFK----DKSQAENVPIGLLSYPVLQAADILLYQADLVPVGIDQDQHLELTRDLAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 173 KLNYIAQaDILVECRPLLSK-VPRLPSLDGKsKMSKSMGNS-ILLDSSEKDISKAVKSMYTDASHLRIEDPGKIEGN--- 247
Cdd:TIGR00233 161 RFNKKFK-NFFPKPESLISKfFPRLMGLSGK-KMSKSDPNSaIFLTDTPKQIKKKIRKAATDGGRVTLFEHREKPGVpnl 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 248 -VVFTYLDAFHSDTAYISELKARYQQGGLGDGSLKKILEECLQDTLKPIRERRKSFISDkaQLIEILRNGSDKSQEESNQ 326
Cdd:TIGR00233 239 lVIYQYLSFFLIDDDKLKEIYEAYKSGKLGYGECKKALIEVLQEFLKEIQERRAEIAEE--ILDKILEPGAKKARETANK 316
|
330
....*....|.
gi 639305404 327 ILNSVKNAFGL 337
Cdd:TIGR00233 317 TLADVYKAMGL 327
|
|
| tRNA-synt_1b |
pfam00579 |
tRNA synthetases class I (W and Y); |
12-293 |
2.71e-51 |
|
tRNA synthetases class I (W and Y);
Pssm-ID: 395461 [Multi-domain] Cd Length: 292 Bit Score: 171.69 E-value: 2.71e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 12 KILTGDRATGQLHLGHFVgSLQQRVALQ-HQYEQTILVADLQGLTDN--GHNPHKVSSNIL---NVVADYLAVGIDTQKT 85
Cdd:pfam00579 7 RVYSGIDPTGPLHLGYLV-PLMKLRQFQqAGHEVFFLIGDLHAIIGDpsKSPERKLLSRETvleNAIKAQLACGLDPEKA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 86 TICLQSAIPALSELTMYYSNLVSVSRLQRNPTVKSEIASKSFGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIE 165
Cdd:pfam00579 86 EIVNNSDWLEHLELAWLLRDLGKHFSLNRMLQFKDVKKRLEQGPGISLGEFTYPLLQAYDILLLKADLQPGGSDQWGNIE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 166 QTNEIVRKLNYiaqaDILVECRPLLskVPRLPSLDGKSKMSKSMGNS-ILLDSSEKDISKAVKSMYTD-ASHLRIEDPGK 243
Cdd:pfam00579 166 LGRDLARRFNK----KIFKKPVGLT--NPLLTGLDGGKKMSKSAGNSaIFLDDDPESVYKKIQKAYTDpDREVRKDLKLF 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 639305404 244 IEG-NVVFTYLDAFHSDTAY--ISELKARYQQGGLGDGSLKKILEECLQDTLK 293
Cdd:pfam00579 240 TFLsNEEIEILEAELGKSPYreAEELLAREVTGLVHGGDLKKAAAEAVNKLLQ 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK12282 |
PRK12282 |
tryptophanyl-tRNA synthetase II; Reviewed |
9-340 |
0e+00 |
|
tryptophanyl-tRNA synthetase II; Reviewed
Pssm-ID: 183400 [Multi-domain] Cd Length: 333 Bit Score: 614.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 9 NKDKILTGDRATGQLHLGHFVGSLQQRVALQHQYEQTILVADLQGLTDNGHNPHKVSSNILNVVADYLAVGIDTQKTTIC 88
Cdd:PRK12282 1 TKPIILTGDRPTGKLHLGHYVGSLKNRVALQNEHEQFVLIADQQALTDNAKNPEKIRRNILEVALDYLAVGIDPAKSTIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 89 LQSAIPALSELTMYYSNLVSVSRLQRNPTVKSEIASKSFGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIEQTN 168
Cdd:PRK12282 81 IQSQIPELAELTMYYMNLVTVARLERNPTVKTEIAQKGFGRSIPAGFLTYPVSQAADITAFKATLVPVGDDQLPMIEQTR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 169 EIVRKLNYIAQADILVECRPLLSKVPRLPSLDGKSKMSKSMGNSILLDSSEKDISKAVKSMYTDASHLRIEDPGKIEGNV 248
Cdd:PRK12282 161 EIVRRFNSLYGTDVLVEPEALLPEAGRLPGLDGKAKMSKSLGNAIYLSDDADTIKKKVMSMYTDPNHIRVEDPGKVEGNV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 249 VFTYLDAFHSDTAYISELKARYQQGGLGDGSLKKILEECLQDTLKPIRERRKSFISDKAQLIEILRNGSDKSQEESNQIL 328
Cdd:PRK12282 241 VFTYLDAFDPDKAEVAELKAHYQRGGLGDVKCKRYLEEVLQELLAPIRERRAEFAKDPGYVLEILKAGSEKAREVAAQTL 320
|
330
....*....|..
gi 639305404 329 NSVKNAFGLSLF 340
Cdd:PRK12282 321 SEVKDAMGLNYF 332
|
|
| TrpS |
COG0180 |
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ... |
10-340 |
3.66e-161 |
|
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439950 [Multi-domain] Cd Length: 330 Bit Score: 453.35 E-value: 3.66e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 10 KDKILTGDRATGQLHLGHFVGSLQQRVALQHQYEQTILVADLQGLTDNgHNPHKVSSNILNVVADYLAVGIDTQKTTICL 89
Cdd:COG0180 3 KKRVLSGIQPTGRLHLGNYLGALKNWVELQDEYECFFFIADLHALTTP-QDPEELRENTREVAADYLAAGLDPEKSTIFV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 90 QSAIPALSELTMYYSNLVSVSRLQRNPTVKSEIAsKSFGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIEQTNE 169
Cdd:COG0180 82 QSDVPEHAELAWLLSCLTPLGELERMPQFKDKSA-KNGKENVNAGLLTYPVLMAADILLYKADLVPVGEDQKQHLELTRD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 170 IVRKLNYIAqADILVECRPLLSK-VPRLPSLDGKSKMSKSMGNSILLDSSEKDISKAVKSMYTDASHLRIEDPGKIEGNV 248
Cdd:COG0180 161 IARRFNHRY-GEVFPEPEALIPEeGARIPGLDGRKKMSKSYGNTINLLDDPKEIRKKIKSAVTDSERLRYDDPGKPEVCN 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 249 VFTYLDAFhSDTAYISELKARYQQGGLGDGSLKKILEECLQDTLKPIRERRKSFISDKAQLIEILRNGSDKSQEESNQIL 328
Cdd:COG0180 240 LFTIYSAF-SGKEEVEELEAEYRAGGIGYGDLKKALAEAVVEFLAPIRERRAELLADPAELDEILAEGAEKARAIAAKTL 318
|
330
....*....|..
gi 639305404 329 NSVKNAFGLSLF 340
Cdd:COG0180 319 AEVREAMGLLYF 330
|
|
| PRK00927 |
PRK00927 |
tryptophanyl-tRNA synthetase; Reviewed |
13-340 |
5.80e-108 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 234866 [Multi-domain] Cd Length: 333 Bit Score: 318.57 E-value: 5.80e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 13 ILTGDRATGQLHLGHFVGSLQQRVALQHQYEQTILVADLQGLTdNGHNPHKVSSNILNVVADYLAVGIDTQKTTICLQSA 92
Cdd:PRK00927 4 VLSGIQPTGKLHLGNYLGAIKNWVELQDEYECFFCIADLHALT-VPQDPEELRENTRELAADYLACGIDPEKSTIFVQSH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 93 IPALSELTMYYSNLVSVSRLQRNPTVKsEIASKSfGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIEQTNEIVR 172
Cdd:PRK00927 83 VPEHAELAWILNCITPLGELERMTQFK-DKSAKQ-KENVSAGLFTYPVLMAADILLYKADLVPVGEDQKQHLELTRDIAR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 173 KLNYIaQADILVECRPLLSKV-PRLPSLDGKS-KMSKS---MGNSILLDSSEKDISKAVKSMYTDASHLRIEDPG---KI 244
Cdd:PRK00927 161 RFNNL-YGEVFPVPEPLIPKVgARVMGLDGPTkKMSKSdpnDNNTINLLDDPKTIAKKIKKAVTDSERLREIRYDlpnKP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 245 EGNVVFTYLDAFHSDTayISELKARYQQGGLGDGSLKKILEECLQDTLKPIRERRKSFISDKAQLIEILRNGSDKSQEES 324
Cdd:PRK00927 240 EVSNLLTIYSALSGES--IEELEAEYEAGGKGYGDFKKDLAEAVVEFLAPIRERYEELLADPAYLDEILAEGAEKARAVA 317
|
330
....*....|....*.
gi 639305404 325 NQILNSVKNAFGLSLF 340
Cdd:PRK00927 318 SKTLKEVREAMGLLRK 333
|
|
| TrpRS_core |
cd00806 |
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) ... |
13-289 |
7.33e-98 |
|
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. TrpRS is a homodimer which attaches Tyr to the appropriate tRNA. TrpRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding
Pssm-ID: 173903 [Multi-domain] Cd Length: 280 Bit Score: 290.64 E-value: 7.33e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 13 ILTGDRATGQLHLGHFVGSLQQRVALQH-QYEQTILVADLQGLTDNGHNPHKVSSNILNVVADYLAVGIDTQKTTICLQS 91
Cdd:cd00806 2 VLSGIQPSGSLHLGHYLGAFRFWVWLQEaGYELFFFIADLHALTVKQLDPEELRQNTRENAKDYLACGLDPEKSTIFFQS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 92 AIPALSELTMYYSNLVSVSRLQRNPTVKSEIAsksFGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIEQTNEIV 171
Cdd:cd00806 82 DVPEHYELAWLLSCVVTFGELERMTGFKDKSA---QGESVNIGLLTYPVLQAADILLYKACLVPVGIDQDPHLELTRDIA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 172 RKLNYIaQADILVECRPLLSKVPRLPSL-DGKSKMSKSMGNS-ILLDSSEKDISKAVKSMYTDASH--LRIEDPGKIEGN 247
Cdd:cd00806 159 RRFNKL-YGEIFPKPAALLSKGAFLPGLqGPSKKMSKSDPNNaIFLTDSPKEIKKKIMKAATDGGRteHRRDGGGPGVSN 237
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 639305404 248 VVFTYLDAFHSDTAYIsELKARYQQGGLGDGSLKKILEECLQ 289
Cdd:cd00806 238 LVEIYSAFFNDDDEEL-EEIDEYRSGGLGYGECKKLLAEAIQ 278
|
|
| trpS |
TIGR00233 |
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ... |
13-337 |
1.91e-78 |
|
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272975 [Multi-domain] Cd Length: 327 Bit Score: 243.01 E-value: 1.91e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 13 ILTGDRATGQLHLGHFVGSLQQRVALQHQYEQTILVADLQGLTDNGHNPHKVSSNILNVVADYLAVGIDTQKTTICLQSA 92
Cdd:TIGR00233 5 VLTGIQPSGKMHLGHYLGAIQTKWLQQFGVELFICIADLHAITVKQTDPDALRKAREELAADYLAVGLDPEKTFIFLQSD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 93 IPALSELTMYYSNLVSVSRLQRNPTVKseiaSKSFGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIEQTNEIVR 172
Cdd:TIGR00233 85 YPEHYELAWLLSCQVTFGELKRMTQFK----DKSQAENVPIGLLSYPVLQAADILLYQADLVPVGIDQDQHLELTRDLAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 173 KLNYIAQaDILVECRPLLSK-VPRLPSLDGKsKMSKSMGNS-ILLDSSEKDISKAVKSMYTDASHLRIEDPGKIEGN--- 247
Cdd:TIGR00233 161 RFNKKFK-NFFPKPESLISKfFPRLMGLSGK-KMSKSDPNSaIFLTDTPKQIKKKIRKAATDGGRVTLFEHREKPGVpnl 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 248 -VVFTYLDAFHSDTAYISELKARYQQGGLGDGSLKKILEECLQDTLKPIRERRKSFISDkaQLIEILRNGSDKSQEESNQ 326
Cdd:TIGR00233 239 lVIYQYLSFFLIDDDKLKEIYEAYKSGKLGYGECKKALIEVLQEFLKEIQERRAEIAEE--ILDKILEPGAKKARETANK 316
|
330
....*....|.
gi 639305404 327 ILNSVKNAFGL 337
Cdd:TIGR00233 317 TLADVYKAMGL 327
|
|
| PRK12283 |
PRK12283 |
tryptophanyl-tRNA synthetase; Reviewed |
11-338 |
1.26e-66 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 183401 [Multi-domain] Cd Length: 398 Bit Score: 214.82 E-value: 1.26e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 11 DKILTGDRATGQLHLGHFVGSLQQRVALQHQYEQTILVADLQGLTDNGHNPHKVSSNILNVVADYLAVGIDTQKTTICLQ 90
Cdd:PRK12283 3 DRVLSGMRPTGRLHLGHYHGVLKNWVKLQHEYECFFFVADWHALTTHYETPEVIEKNVWDMVIDWLAAGVDPAQATLFIQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 91 SAIPALSELTMYYSNLVSVSRLQRNPTVKSEI---ASKSFGASipaGFLTYPISQAADITAFRATLIPVGDDQLPMIEQT 167
Cdd:PRK12283 83 SKVPEHAELHLLLSMITPLGWLERVPTYKDQQeklKEKDLSTY---GFLGYPLLQSADILIYRAGLVPVGEDQVPHVEMT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 168 NEIVRKLNYI--------------------------------------------AQA-----------D----------- 181
Cdd:PRK12283 160 REIARRFNHLygrepgfeekaeaaikklgkkraklyhelrnayqeegddealeqARAllqeqqnlsmgDrerlfgylega 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 182 ---ILVECRPLLSKVPRLPSLDGKsKMSKSMGNSILLDSSEKDISKAVKSMYTDASHLRIEDPGKIEGNVVFtyldAFH- 257
Cdd:PRK12283 240 gkiILPEPQALLTEASKMPGLDGQ-KMSKSYGNTIGLREDPESVTKKIRTMPTDPARVRRTDPGDPEKCPVW----QLHq 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 258 --SDtayiSELKARYQQG----GLGDGSLKKILEECLQDTLKPIRERRKSFISDKAQLIEILRNGSDKSQEESNQILNSV 331
Cdd:PRK12283 315 vySD----EETKEWVQKGcrsaGIGCLECKQPVIDAILREQQPMRERAQKYEDDPSLVRAIVADGCEKARKVARETMRDV 390
|
....*..
gi 639305404 332 KNAFGLS 338
Cdd:PRK12283 391 REAMGLS 397
|
|
| PRK12556 |
PRK12556 |
tryptophanyl-tRNA synthetase; Provisional |
9-338 |
1.94e-52 |
|
tryptophanyl-tRNA synthetase; Provisional
Pssm-ID: 183592 [Multi-domain] Cd Length: 332 Bit Score: 176.07 E-value: 1.94e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 9 NKDKILTGDRATGQLHLGHFVGSLQQRVALQHQYEQTIL--VADLQGLTdNGHNPHKVSSNILNVVADYLAVGIDTQKTT 86
Cdd:PRK12556 2 SEKIMLTGIKPTGYPHLGNYIGAIKPALQMAKNYEGKALyfIADYHALN-AVHDPEQFRSYTREVAATWLSLGLDPEDVI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 87 ICLQSAIPALSELTMYYSNLVSVSRLQRNPTVKSEI-----ASKSFGASIPAGFLTYPISQAADITAFRATLIPVGDDQL 161
Cdd:PRK12556 81 FYRQSDVPEIFELAWILSCLTPKGLMNRAHAYKAKVdqnkeAGLDLDAGVNMGLYTYPILMAADILLFQATHVPVGKDQI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 162 PMIEQTNEIVRKLNYIAQADILVECRPLLSKVPRLPSLDGKsKMSKSMGNSILLDSSEKDISKAVKSMYTDAShlRIEDP 241
Cdd:PRK12556 161 QHIEIARDIATYFNHTFGDTFTLPEYVIQEEGAILPGLDGR-KMSKSYGNVIPLFAEQEKLRKLIFKIKTDSS--LPNEP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 242 GKIEGNVVFTYLDAFHSDTAyISELKARYQQgGLGDGSLKKILEECLQDTLKPIRERRKSFISDKAQLIEILRNGSDKSQ 321
Cdd:PRK12556 238 KDPETSALFTIYKEFATEEE-VQSMREKYET-GIGWGDVKKELFRVVDRELAGPREKYAMYMNEPSLLDEALEKGAERAR 315
|
330
....*....|....*..
gi 639305404 322 EESNQILNSVKNAFGLS 338
Cdd:PRK12556 316 EIAKPNLAEIKKAIGFE 332
|
|
| tRNA-synt_1b |
pfam00579 |
tRNA synthetases class I (W and Y); |
12-293 |
2.71e-51 |
|
tRNA synthetases class I (W and Y);
Pssm-ID: 395461 [Multi-domain] Cd Length: 292 Bit Score: 171.69 E-value: 2.71e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 12 KILTGDRATGQLHLGHFVgSLQQRVALQ-HQYEQTILVADLQGLTDN--GHNPHKVSSNIL---NVVADYLAVGIDTQKT 85
Cdd:pfam00579 7 RVYSGIDPTGPLHLGYLV-PLMKLRQFQqAGHEVFFLIGDLHAIIGDpsKSPERKLLSRETvleNAIKAQLACGLDPEKA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 86 TICLQSAIPALSELTMYYSNLVSVSRLQRNPTVKSEIASKSFGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIE 165
Cdd:pfam00579 86 EIVNNSDWLEHLELAWLLRDLGKHFSLNRMLQFKDVKKRLEQGPGISLGEFTYPLLQAYDILLLKADLQPGGSDQWGNIE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 166 QTNEIVRKLNYiaqaDILVECRPLLskVPRLPSLDGKSKMSKSMGNS-ILLDSSEKDISKAVKSMYTD-ASHLRIEDPGK 243
Cdd:pfam00579 166 LGRDLARRFNK----KIFKKPVGLT--NPLLTGLDGGKKMSKSAGNSaIFLDDDPESVYKKIQKAYTDpDREVRKDLKLF 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 639305404 244 IEG-NVVFTYLDAFHSDTAY--ISELKARYQQGGLGDGSLKKILEECLQDTLK 293
Cdd:pfam00579 240 TFLsNEEIEILEAELGKSPYreAEELLAREVTGLVHGGDLKKAAAEAVNKLLQ 292
|
|
| PLN02886 |
PLN02886 |
aminoacyl-tRNA ligase |
7-336 |
5.37e-48 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215478 [Multi-domain] Cd Length: 389 Bit Score: 166.14 E-value: 5.37e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 7 PLNKDKILTGDRATGQLHLGHFVGSLQQRVALQHQYEQTILVADLQGLTDNgHNPHKVSSNILNVVADYLAVGIDTQKTT 86
Cdd:PLN02886 43 VARKKRVVSGVQPTGSIHLGNYLGAIKNWVALQETYDTFFCVVDLHAITLP-HDPRELGKATRSTAAIYLACGIDPSKAS 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 87 ICLQSAIPALSELTMYYSNLVSVSRLQRNPTVKsEIASKSFGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIEQ 166
Cdd:PLN02886 122 VFVQSHVPAHAELMWLLSCSTPIGWLNKMIQFK-EKSRKAGDENVGVGLLTYPVLMASDILLYQADLVPVGEDQKQHLEL 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 167 TNEIVRKLNYIAQA-----------DILVECRPLLSKV-PRLPSL-DGKSKMSKSM---GNSI-LLDSSEkDISKAVKSM 229
Cdd:PLN02886 201 TRDIAERVNNLYGGrkwkklggrggSVFKVPEALIPPAgARVMSLtDGTSKMSKSApsdQSRInLLDPPD-VIANKIKRC 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 230 YTDA-SHLRIEDPGKIEGNVVFTYLDAFHSDTAyiSELKAryQQGGLGDGSLKKILEECLQDTLKPIRERRKSFISDKAQ 308
Cdd:PLN02886 280 KTDSfPGLEFDNPERPECNNLLSIYQLVTGKTK--EEVLA--ECGDMRWGDFKPLLTDALIEHLSPIQVRYEEIMSDPSY 355
|
330 340
....*....|....*....|....*...
gi 639305404 309 LIEILRNGSDKSQEESNQILNSVKNAFG 336
Cdd:PLN02886 356 LDSVLKEGADAAAEIADRTLANVYQAMG 383
|
|
| PRK12284 |
PRK12284 |
tryptophanyl-tRNA synthetase; Reviewed |
12-337 |
9.57e-40 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 237036 [Multi-domain] Cd Length: 431 Bit Score: 145.15 E-value: 9.57e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 12 KILTGDRATGQLHLGHFVGSLQQRVA--LQHQYEQTILVADLQGL--TDNghnPHKVSSNILNVVADYLAVGIDTQKTTI 87
Cdd:PRK12284 4 RVLTGITTTGTPHLGNYAGAIRPAIAasRQPGVESFYFLADYHALikCDD---PARIQRSTLEIAATWLAAGLDPERVTF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 88 CLQSAIPALSELTMYYSNLVSVSRLQRNPTVKSEI-----ASKSFGASIPAGFLTYPISQAADITAFRATLIPVGDDQLP 162
Cdd:PRK12284 81 YRQSDIPEIPELTWLLTCVAGKGLLNRAHAYKAAVdknvaAGEDPDAGVTAGLFMYPVLMAADILMFNAHKVPVGRDQIQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 163 MIEQTNEIVRKLNYIAQADILVECRPLLSK-VPRLPSLDGKsKMSKSMGNSILLDSSEKDISKAVKSMYTDaSHLRIEdP 241
Cdd:PRK12284 161 HIEMARDIAQRFNHLYGGEFFVLPEAVIEEsVATLPGLDGR-KMSKSYDNTIPLFAPREELKKAIFSIVTD-SRAPGE-P 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 242 GKIEGNVVFTYLDAFHSdTAYISELKARYQQgGLGDGSLKKILEECLQDTLKPIRERRKSFISDKAQLIEILRNGSDKSQ 321
Cdd:PRK12284 238 KDTEGSALFQLYQAFAT-PEETAAFRQALAD-GIGWGDAKQRLFERIDRELAPMRERYEALIARPADIEDILLAGAAKAR 315
|
330
....*....|....*.
gi 639305404 322 EESNQILNSVKNAFGL 337
Cdd:PRK12284 316 RIATPFLAELREAVGL 331
|
|
| PRK12285 |
PRK12285 |
tryptophanyl-tRNA synthetase; Reviewed |
13-312 |
2.50e-20 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 237037 [Multi-domain] Cd Length: 368 Bit Score: 90.31 E-value: 2.50e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 13 ILTGDRATGQLHLGH-----FVGSLQQRVAlqhqyEQTILVADLQGLTDNGHNPHKVSSNILNVVADYLAVGIDTQKTTI 87
Cdd:PRK12285 69 VYTGFMPSGPMHIGHkmvfdELKWHQEFGA-----NVYIPIADDEAYAARGLSWEETREWAYEYILDLIALGFDPDKTEI 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 88 CLQSAIPALSELTMYYSNLVSVSRLQrnptvkseiASKSFGASIPAGFLTYPISQAADI------TAFRATLIPVGDDQL 161
Cdd:PRK12285 144 YFQSENIKVYDLAFELAKKVNFSELK---------AIYGFTGETNIGHIFYPATQAADIlhpqleEGPKPTLVPVGIDQD 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 162 PMIEQTNEIVRKLN----YIAQADIlvecrplLSKVprLPSLDGkSKMSKSMGNS-ILLDSSEKDISKAVKSMYTDAshl 236
Cdd:PRK12285 215 PHIRLTRDIAERLHggygFIKPSST-------YHKF--MPGLTG-GKMSSSKPESaIYLTDDPETVKKKIMKALTGG--- 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 237 R--IEDPGKIEGN----VVFTYLdAFH--SDTAYISELKARYQQGGLGDGSLKKILEECLQDTLKPIRERRKSfISDKAQ 308
Cdd:PRK12285 282 RatLEEQRKLGGEpdecVVYELL-LYHleEDDKELKEIYEECRSGELLCGECKKEAAEKIAEFLKEHQEKREE-AREILE 359
|
....
gi 639305404 309 LIEI 312
Cdd:PRK12285 360 KYLY 363
|
|
| Tyr_Trp_RS_core |
cd00395 |
catalytic core domain of tyrosinyl-tRNA and tryptophanyl-tRNA synthetase; Tyrosinyl-tRNA ... |
13-234 |
5.23e-19 |
|
catalytic core domain of tyrosinyl-tRNA and tryptophanyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS)/Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. These enzymes attach Tyr or Trp, respectively, to the appropriate tRNA. These class I enzymes are homodimers, which aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173893 [Multi-domain] Cd Length: 273 Bit Score: 85.43 E-value: 5.23e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 13 ILTGDRATGQ-LHLGHFVGSLQQRVALQHQYEQTILVADLQGLT---------DNGHNPHKVSSNILNVVADYLAVGIDT 82
Cdd:cd00395 2 LYCGIDPTADsLHIGHLIGLLTFRRFQHAGHRPIFLIGGQTGIIgdpsgkkseRTLNDPEEVRQNIRRIAAQYLAVGIFE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 83 QKT--TICLQSAIPALSELTMY---YSNLVSVSRLQRNPTVKSEIASksfgaSIPAGFLTYPISQAADI----TAFRATL 153
Cdd:cd00395 82 DPTqaTLFNNSDWPGPLAHIQFlrdLGKHVYVNYMERKTSFQSRSEE-----GISATEFTYPPLQAADFlllnTTEGCDI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 154 IPVGDDQLPMIEQTNEIVRKLNYIAQADILVecrpllskVPRLPSLDGKsKMSKSMGNSILLDsSEKDISKAVKSMYTDA 233
Cdd:cd00395 157 QPGGSDQWGNITLGRELARRFNGFTIAEGLT--------IPLVTKLDGP-KFGKSESGPKWLD-TEKTSPYEFYQFWINA 226
|
.
gi 639305404 234 S 234
Cdd:cd00395 227 V 227
|
|
| PTZ00126 |
PTZ00126 |
tyrosyl-tRNA synthetase; Provisional |
108-312 |
4.61e-16 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 240282 [Multi-domain] Cd Length: 383 Bit Score: 78.19 E-value: 4.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 108 SVSRLQRNptvkSEIASKSFGASIPAGFLTYPISQAADITAFRATLIPVGDDQlpmieqtneivRKLNYIAQ--ADILVE 185
Cdd:PTZ00126 172 NITRIKRC----SQIMGRSEGDEQPCAQILYPCMQCADIFYLKADICQLGMDQ-----------RKVNMLAReyCDKKKI 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 186 CR-PLLSKVPRLPSL-DGKSKMSKSMGNS-ILLDSSEKDISKAVKSMYTDashlriedPGKIEGNVVFTYL--------- 253
Cdd:PTZ00126 237 KKkPIILSHHMLPGLlEGQEKMSKSDPNSaIFMEDSEEDVNRKIKKAYCP--------PGVIEGNPILAYFksivfpafn 308
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639305404 254 -------DAFHSDTAY--ISELKARYQQGGLGDGSLKKILEECLQDTLKPIRERRKSFISDKAQLIEI 312
Cdd:PTZ00126 309 sftvlrkEKNGGDVTYttYEELEKDYLSGALHPGDLKPALAKYLNLMLQPVRDHFQNNPEAKSLLSEV 376
|
|
| PRK08560 |
PRK08560 |
tyrosyl-tRNA synthetase; Validated |
20-301 |
4.00e-15 |
|
tyrosyl-tRNA synthetase; Validated
Pssm-ID: 236286 [Multi-domain] Cd Length: 329 Bit Score: 74.90 E-value: 4.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 20 TGQLHLGHFVgSLQQRVALQHQ-YEQTILVADLQGLTDNghnphKVSSNILNVVADYL-----AVGIDTQKTTICLQSAI 93
Cdd:PRK08560 40 SGKIHLGHLL-TMNKLADLQKAgFKVTVLLADWHAYLND-----KGDLEEIRKVAEYNkkvfeALGLDPDKTEFVLGSEF 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 94 pALSEltMYYSNL------VSVSRLQRNPTvksEIASKSfgASIPAGFLTYPISQAADITAFRATlIPVGDdqlpmIEQt 167
Cdd:PRK08560 114 -QLDK--EYWLLVlklaknTTLARARRSMT---IMGRRM--EEPDVSKLVYPLMQVADIFYLDVD-IAVGG-----MDQ- 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 168 neivRKLNYIAqadilvecRPLLSKV----------PRLPSLDGKS-KMSKS-MGNSILLDSSEKDISKAVKSMYTDash 235
Cdd:PRK08560 179 ----RKIHMLA--------REVLPKLgykkpvcihtPLLTGLDGGGiKMSKSkPGSAIFVHDSPEEIRRKIKKAYCP--- 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 236 lriedPGKIEGN--------VVFTYLDA--------FHSDTAYIS--ELKARYQQGGLGDGSLKKILEECLQDTLKPIRE 297
Cdd:PRK08560 244 -----PGEVEGNpvleiakyHIFPRYDPfvierpekYGGDLEYESyeELERDYAEGKLHPMDLKNAVAEYLIEILEPVRE 318
|
....
gi 639305404 298 RRKS 301
Cdd:PRK08560 319 YLEE 322
|
|
| PLN02486 |
PLN02486 |
aminoacyl-tRNA ligase |
74-299 |
6.85e-12 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178104 Cd Length: 383 Bit Score: 65.92 E-value: 6.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 74 DYLAVGIDTQKTTIclqsaipaLSEL----TMYYSNLVSVSRlqrnpTVKSEIASKSFG--ASIPAGFLTYPISQAAdiT 147
Cdd:PLN02486 139 DIIACGFDVERTFI--------FSDFdyvgGAFYKNMVKIAK-----CVTLNQVRGIFGfsGEDNIGKISFPAVQAA--P 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 148 AFRAT-------------LIPVGDDQLPMIEQTNEIVRKLNYIAQAdiLVECRpllskvpRLPSLDGKS-KMSKSMGNS- 212
Cdd:PLN02486 204 SFPSSfphlfggkdklrcLIPCAIDQDPYFRMTRDVAPRLGYYKPA--LIESR-------FFPALQGESgKMSASDPNSa 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 213 ILLDSSEKDISKAVKSMYTDASHLRIEDPGKIEGN----VVFTYLDAFHSDTAYISELKARYQQGGLGDGSLKKILEECL 288
Cdd:PLN02486 275 IYVTDTPKEIKNKINKYAFSGGQDTVEEHRELGANlevdIPWKYLNFFLEDDAELERIKKEYGSGRMLTGEVKKRLIEVL 354
|
250
....*....|.
gi 639305404 289 QDTLKPIRERR 299
Cdd:PLN02486 355 TEIVERHQRAR 365
|
|
| tyrS |
TIGR00234 |
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up ... |
12-336 |
5.33e-10 |
|
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up tryptophanyl-tRNA synthetases at scores of 0 and below. The proteins found by this model have a deep split between two groups. One group contains bacterial and organellar eukaryotic examples. The other contains archaeal and cytosolic eukaryotic examples. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272976 [Multi-domain] Cd Length: 378 Bit Score: 60.10 E-value: 5.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 12 KILTGDRATGQ-LHLGHFVGSLQQRVALQHQYEQTILVADLQGLTDN--GHN-------PHKVSSNILNVVAdYLAVGID 81
Cdd:TIGR00234 33 KLYLGFDPTAPsLHLGHLVPLLKLRDFQQAGHEVIVLLGDFTALIGDptGKSevrkiltREEVQENAENIKK-QIARFLD 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 82 TQKTTICLQSAIpalsELTMYYSNLvsVSRLQRNPTVKSEIASKSFGASIPAGF----LTYPISQAADITAFRATLIPVG 157
Cdd:TIGR00234 112 FEKAKFVYNSEW----LLKLNYTDF--IRLLGKIFTVNRMLRRDAFSSRFEENIslheFIYPLLQAYDFVYLNVDLQLGG 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 158 DDQLPMIEQTNEIVRKLNYIAQADILVecrPLLSKvprlpsLDGKsKMSKSMGNSILLD-----------SSEKDISKAV 226
Cdd:TIGR00234 186 SDQWFNIRKGRDLARENLPSLQFGLTV---PLLTP------ADGE-KMGKSLGGAVSLDegkydfyqkviNTPDELVKKY 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 227 KSMYTDASHLRIED--------PGKIEGNVVFTYLDAFH---SDTAYISELKARYQQGGLGDGSLKKILEECLQDTLKPI 295
Cdd:TIGR00234 256 LKLFTFLGLEEIEQlvelkgpnPREVKENLALEITKYVHgpeAALAAEEISEAIFSGGLNPDEVPIFRPEKFGGPITLAD 335
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 639305404 296 RERRKSFISDKAQLIEILRNGSDKSQEESNQILNSVKNAFG 336
Cdd:TIGR00234 336 LLVLSGLFPSKSEARRDIKNGGVYINGEKVEDLEPIRKELE 376
|
|
| TyrRS_core |
cd00805 |
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) ... |
23-219 |
2.44e-09 |
|
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) catalytic core domain. TyrRS is a homodimer which attaches Tyr to the appropriate tRNA. TyrRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formationof the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173902 [Multi-domain] Cd Length: 269 Bit Score: 57.23 E-value: 2.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 23 LHLGHFVGSLQQRVALQHQYEQTILVADLQGLTDN--------GHNP----HKVSSNILNVVADYLaVGIDTQKTTICLQ 90
Cdd:cd00805 14 LHLGHLVPLMKLRDFQQAGHEVIVLIGDATAMIGDpsgkseerKLLDleliRENAKYYKKQLKAIL-DFIPPEKAKFVNN 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 91 SAI-PALSELTMY-YSNLVSVSRLQRNPTVKSEIASksfGASIPAGFLTYPISQAADITAFRATLIPVGDDQLPMIEQTN 168
Cdd:cd00805 93 SDWlLSLYTLDFLrLGKHFTVNRMLRRDAVKVRLEE---EEGISFSEFIYPLLQAYDFVYLDVDLQLGGSDQRGNITLGR 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 639305404 169 EIVRKLNYIAQADILvecrpllskVPRLPSLDGKsKMSKSMGNSI---LLDSSE 219
Cdd:cd00805 170 DLIRKLGYKKVVGLT---------TPLLTGLDGG-KMSKSEGNAIwdpVLDSPY 213
|
|
| PTZ00348 |
PTZ00348 |
tyrosyl-tRNA synthetase; Provisional |
69-311 |
2.59e-04 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 173541 [Multi-domain] Cd Length: 682 Bit Score: 42.97 E-value: 2.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 69 LNVVADYL-----AVGIDTQKTtICLQSAIPALSELTMYYSNLVSVSRLQRNPTVKS--EIASKSFGaSIPAGFLTYPIS 141
Cdd:PTZ00348 89 IRIVGRYLievwkAAGMDMDKV-LFLWSSEEITNHANTYWRTVLDIGRQNTIARIKKccTIMGKTEG-TLTAAQVLYPLM 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 142 QAADITAFRATLIPVGDDQlpmieqtneivRKLNYIAQ--ADIL-VECRPLLSKVPRLPSL-DGKSKMSKSMGNS-ILLD 216
Cdd:PTZ00348 167 QCADIFFLKADICQLGLDQ-----------RKVNMLAReyCDLIgRKLKPVILSHHMLAGLkQGQAKMSKSDPDSaIFME 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639305404 217 SSEKDISKAVKSMY---TDASHLRIEDPGKI----EGNVVFTYLD----------AFHSDTAYIS--ELKARYQQGGLGD 277
Cdd:PTZ00348 236 DTEEDVARKIRQAYcprVKQSASEITDDGAPvatdDRNPVLDYFQcvvyarpgavATIDGTTYATyeDLEQAFVSDEVSE 315
|
250 260 270
....*....|....*....|....*....|....*.
gi 639305404 278 GSLKKILEECLQDTLKPIrerRKSFISDK--AQLIE 311
Cdd:PTZ00348 316 EALKSCLIDEVNALLEPV---RQHFASNPeaHELLE 348
|
|
| |
