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Conserved domains on  [gi|639340887|ref|WP_024600859|]
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MULTISPECIES: IS5 family transposase [Gammaproteobacteria]

Protein Classification

transposase family protein( domain architecture ID 1750073)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  21439812

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
transpos_IS5_3 NF033580
IS5 family transposase;
29-248 3.31e-89

IS5 family transposase;


:

Pssm-ID: 468097 [Multi-domain]  Cd Length: 257  Bit Score: 264.44  E-value: 3.31e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887  29 DHRKTLEGILYKMRTGIPWRDLPSDFGRWSAIYRRFNLWSKKGILNELFRALSRDA--DMDWVFIDGSIVRAHQHSCGAR 106
Cdd:NF033580  30 DDREVLNAILYVLRTGCPWRDLPERFGPWSTVYRRFRRWSEAGVWERLFEALLAELriDWERLAIDSTIVRAHQSAAGAK 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 107 TA---DNESIGKSRGGNSTKIHLAVDSGGLPVYYELSCGNTHDIVHAESLVANCPTSNM-----VVADKGYDSEKLRAFV 178
Cdd:NF033580 110 KTgpnGYQAIGRSKGGLKTKIHIAVDALGLPLAFVLTGANVHDSKGALPLLDGLPVLRPprpkhLLADKGYDSDALRAAL 189
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 179 RDNNATPVIPRKGNSLvgNEDIDWCMYKYRHLVENAFGRIKQYRGIATRYEKLERNYHSMLALAFTMMWL 248
Cdd:NF033580 190 RERGAVPVIPRRRNRL--RPAYDFRLYKKRWVVERTFAWLKRFRRLATRYEKLARNFLAFVHLACIRIWL 257
 
Name Accession Description Interval E-value
transpos_IS5_3 NF033580
IS5 family transposase;
29-248 3.31e-89

IS5 family transposase;


Pssm-ID: 468097 [Multi-domain]  Cd Length: 257  Bit Score: 264.44  E-value: 3.31e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887  29 DHRKTLEGILYKMRTGIPWRDLPSDFGRWSAIYRRFNLWSKKGILNELFRALSRDA--DMDWVFIDGSIVRAHQHSCGAR 106
Cdd:NF033580  30 DDREVLNAILYVLRTGCPWRDLPERFGPWSTVYRRFRRWSEAGVWERLFEALLAELriDWERLAIDSTIVRAHQSAAGAK 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 107 TA---DNESIGKSRGGNSTKIHLAVDSGGLPVYYELSCGNTHDIVHAESLVANCPTSNM-----VVADKGYDSEKLRAFV 178
Cdd:NF033580 110 KTgpnGYQAIGRSKGGLKTKIHIAVDALGLPLAFVLTGANVHDSKGALPLLDGLPVLRPprpkhLLADKGYDSDALRAAL 189
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 179 RDNNATPVIPRKGNSLvgNEDIDWCMYKYRHLVENAFGRIKQYRGIATRYEKLERNYHSMLALAFTMMWL 248
Cdd:NF033580 190 RERGAVPVIPRRRNRL--RPAYDFRLYKKRWVVERTFAWLKRFRRLATRYEKLARNFLAFVHLACIRIWL 257
COG3293 COG3293
Transposase [Mobilome: prophages, transposons];
5-100 1.50e-25

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442522 [Multi-domain]  Cd Length: 98  Bit Score: 96.20  E-value: 1.50e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887   5 MLTDGTWNVLSKVMYLSGRIYNKP-DHRKTLEGILYKMRTGIPWRDLPSDFGRWSAIYRRFNLWSKKGILNELFRALSRd 83
Cdd:COG3293    8 DLTDAQWARIEPLLPGPDKGGRPRhDDREVVNAILYVLRTGCPWRDLPRDFGPWRTVERRFRRWRRLGRWERLAEALLA- 86
                         90
                 ....*....|....*..
gi 639340887  84 admdwVFIDGSIVRAHQ 100
Cdd:COG3293   87 -----AVIDASSVRAHQ 98
DUF4096 pfam13340
Putative transposase of IS4/5 family (DUF4096);
6-77 8.65e-24

Putative transposase of IS4/5 family (DUF4096);


Pssm-ID: 433130  Cd Length: 76  Bit Score: 91.01  E-value: 8.65e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639340887    6 LTDGTWNVLSKVMYLSGR----IYNKPDHRKTLEGILYKMRTGIPWRDLPSDFGRWSAIYRRFNLWSKKGILNELF 77
Cdd:pfam13340   1 LTDEQWARIEPLLPPPKRrgdgRPRKHDLREVLNAILYVLRTGCPWRDLPEDFGPWSTVYRRFRRWSRAGVWERLH 76
transpos_IS5_2 NF033579
IS5 family transposase;
123-238 8.29e-15

IS5 family transposase;


Pssm-ID: 468096 [Multi-domain]  Cd Length: 287  Bit Score: 72.32  E-value: 8.29e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 123 KIHLAVDSGGLPV-YYELSCGNTHDIVHAESLVANCPT-SNMVVADKGYDSEKLRAFVRDNNATPVIP-RKGNSLVG--- 196
Cdd:NF033579 141 KVHLAVDVKTGEIlAVEVTTNKVHDAKVLPDLLRQIPEdIDSVLADGAYDTKKCHEAIRERGARPLIPpRKNARLWKegk 220
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 639340887 197 --NEDID------------WCMYKYRHLVENAFGRIKQYRGiatryEKLE-RNYHSM 238
Cdd:NF033579 221 arNAAIReirrlgrelwkkWSGYHRRSLVETAFSRLKRLLG-----ERLRaRNFDRQ 272
transpos_IS5_4 NF033581
IS5 family transposase;
44-244 4.39e-14

IS5 family transposase;


Pssm-ID: 468098 [Multi-domain]  Cd Length: 284  Bit Score: 70.04  E-value: 4.39e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887  44 GIPWRDLPSDfgrwSAIYRRFNLWSKKGILNELFRALSRDADM------DWVFIDGSIVRA-HQHSCGARTADNESIGKS 116
Cdd:NF033581  70 GLSEDDVPDA----STIWRFRELLEEHLLAEALFAEVNRQLLAkgllskEGVIVDATLIPApRSPKKRDKKRDPDMRQTK 145
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 117 RGGNST---KIHLAVDS-GGLPVYYELSCGNTHDIVHAESLVANcpTSNMVVADKGYDSEKLRAFVRDNNATPVIPRKG- 191
Cdd:NF033581 146 KGKKSRhgyKAHIGVDPkSGLVHSLVTTPANVHDSRAAKELLHG--DEKTVYADKGYDGDEGYQGLREAGVKPHIPRKKs 223
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 639340887 192 -NSLVGNEDIdwCMYKY----RHLVENAFGRIKQYRGIA-TRYEKLERNYHSMLALAFT 244
Cdd:NF033581 224 rNRPLTEAQK--RRNRLkskiRARVEHVFGVLKRFFGLSkVRYRGLKRVGARFNLIAAL 280
transpos_IS982 NF033520
IS982 family transposase; Currently, there are 46 seed sequences in this family.
61-236 1.84e-11

IS982 family transposase; Currently, there are 46 seed sequences in this family.


Pssm-ID: 468056 [Multi-domain]  Cd Length: 243  Bit Score: 62.25  E-value: 1.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887  61 YRRFN------LWSKKGILNELFRALSRDADMdWVFIDGS------IVRAHQHSCGARTADnesIGKSRGGNST----KI 124
Cdd:NF033520  41 YSRFNrrcrrlLPLIEAIRQELAKKTKSEETG-IAIIDSTpipvchNKRIKRHKVFKGIAD---RGYCASKKGWfygfKL 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 125 HLAVDSGGLPVYYELSCGNTHDIVHAESLVANCPTSNMVVADKGYDSEKLRAFVRDNNATPVIPRKGNSLVGNEDI-DWC 203
Cdd:NF033520 117 HLLVNLSGEIVSYVITPANVHDRKVLEDLLLTKPLPGKLFGDKGYISKELQEKLKEQGITLITPLRKNMKEKLEKPnDKL 196
                        170       180       190
                 ....*....|....*....|....*....|...
gi 639340887 204 MYKYRHLVENAFGRIKQYRGIatryeklERNYH 236
Cdd:NF033520 197 LLRKRKRIETVFSQLKNQFGI-------EHSRA 222
transpos_IS4_1 NF033592
IS4 family transposase;
58-169 1.38e-06

IS4 family transposase;


Pssm-ID: 468101 [Multi-domain]  Cd Length: 332  Bit Score: 48.41  E-value: 1.38e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887  58 SAIYRRFNLwSKKGILNELFRALSR-------DADMDWVF-----IDGSIVRAHQHSCGARTAdnesigkSRGGNST--- 122
Cdd:NF033592  67 SALSKARKR-LPVEFLKELFERLLAqlqlgqlLPRKLWRGlrvlaVDGTTIRLPDSLENWAPG-------RGGKNSFpgv 138
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 639340887 123 KIHLAVD-SGGLPVYYELSCGNTHDIVHAESLVANCPTSNMVVADKGY 169
Cdd:NF033592 139 KLHLLYDlLSGLPLDAAITPGKTHERTLLRQLLETLPPGDLLLFDRGY 186
transpos_IS1182 NF033551
IS1182 family transposase; Members of this family are transposases of the IS1182 family. ...
123-188 6.47e-06

IS1182 family transposase; Members of this family are transposases of the IS1182 family. About two-thirds of the members of this family have an extra domain between the middle and the C-terminal domain, about 50 amino acids in size and containing four invariant Cys residues.


Pssm-ID: 468080 [Multi-domain]  Cd Length: 437  Bit Score: 46.55  E-value: 6.47e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639340887 123 KIHLAVDS-GGLPVYYELSCGNTHD----IVHAESLVANC---PTSnmVVADKGYDSEKLRAFVRDNNATPVIP 188
Cdd:NF033551 219 NVQIAVDTeSGLIVAVEVTPGNGHDggqlIPLLEQVEERLgllPEE--VLADAGYGSEENLEALEERGIEPVIP 290
 
Name Accession Description Interval E-value
transpos_IS5_3 NF033580
IS5 family transposase;
29-248 3.31e-89

IS5 family transposase;


Pssm-ID: 468097 [Multi-domain]  Cd Length: 257  Bit Score: 264.44  E-value: 3.31e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887  29 DHRKTLEGILYKMRTGIPWRDLPSDFGRWSAIYRRFNLWSKKGILNELFRALSRDA--DMDWVFIDGSIVRAHQHSCGAR 106
Cdd:NF033580  30 DDREVLNAILYVLRTGCPWRDLPERFGPWSTVYRRFRRWSEAGVWERLFEALLAELriDWERLAIDSTIVRAHQSAAGAK 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 107 TA---DNESIGKSRGGNSTKIHLAVDSGGLPVYYELSCGNTHDIVHAESLVANCPTSNM-----VVADKGYDSEKLRAFV 178
Cdd:NF033580 110 KTgpnGYQAIGRSKGGLKTKIHIAVDALGLPLAFVLTGANVHDSKGALPLLDGLPVLRPprpkhLLADKGYDSDALRAAL 189
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 179 RDNNATPVIPRKGNSLvgNEDIDWCMYKYRHLVENAFGRIKQYRGIATRYEKLERNYHSMLALAFTMMWL 248
Cdd:NF033580 190 RERGAVPVIPRRRNRL--RPAYDFRLYKKRWVVERTFAWLKRFRRLATRYEKLARNFLAFVHLACIRIWL 257
COG3293 COG3293
Transposase [Mobilome: prophages, transposons];
5-100 1.50e-25

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442522 [Multi-domain]  Cd Length: 98  Bit Score: 96.20  E-value: 1.50e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887   5 MLTDGTWNVLSKVMYLSGRIYNKP-DHRKTLEGILYKMRTGIPWRDLPSDFGRWSAIYRRFNLWSKKGILNELFRALSRd 83
Cdd:COG3293    8 DLTDAQWARIEPLLPGPDKGGRPRhDDREVVNAILYVLRTGCPWRDLPRDFGPWRTVERRFRRWRRLGRWERLAEALLA- 86
                         90
                 ....*....|....*..
gi 639340887  84 admdwVFIDGSIVRAHQ 100
Cdd:COG3293   87 -----AVIDASSVRAHQ 98
DUF4096 pfam13340
Putative transposase of IS4/5 family (DUF4096);
6-77 8.65e-24

Putative transposase of IS4/5 family (DUF4096);


Pssm-ID: 433130  Cd Length: 76  Bit Score: 91.01  E-value: 8.65e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639340887    6 LTDGTWNVLSKVMYLSGR----IYNKPDHRKTLEGILYKMRTGIPWRDLPSDFGRWSAIYRRFNLWSKKGILNELF 77
Cdd:pfam13340   1 LTDEQWARIEPLLPPPKRrgdgRPRKHDLREVLNAILYVLRTGCPWRDLPEDFGPWSTVYRRFRRWSRAGVWERLH 76
DDE_Tnp_1 pfam01609
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
89-246 7.81e-17

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.


Pssm-ID: 376573 [Multi-domain]  Cd Length: 196  Bit Score: 76.13  E-value: 7.81e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887   89 VFIDGSIVRAHQHSCGARTADNEsiGKSRGGnsTKIHLAVD-SGGLPVYYELSCGNTHDIVHAESLVANCPTSN--MVVA 165
Cdd:pfam01609   7 LIIDSTTIRTPGTGEDARWGYDG--GKRRYG--YKLHIAVDtRTGLILAVVLTPGNVHDSKGLLQLLDELRRRKgrLVLA 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887  166 DKGYDSEKLRAFVRDNNATPVIPRKGNSLVGNEDID--------------------------------WCMYKYRHLVEN 213
Cdd:pfam01609  83 DAGYGGKELLDKLEEKGVDYLIRLKKNAKLIDDKRRgrlrkhgklkiltkvdklkgrvnstllsaetlAELYRRRWQIER 162
                         170       180       190
                  ....*....|....*....|....*....|....
gi 639340887  214 AFGRIKQ-YRGIATRYEKLERNYHSMLALAFTMM 246
Cdd:pfam01609 163 VFKWLKRvFGLDRLRYRGLNAVEAELLLLALAYN 196
transpos_IS5_2 NF033579
IS5 family transposase;
123-238 8.29e-15

IS5 family transposase;


Pssm-ID: 468096 [Multi-domain]  Cd Length: 287  Bit Score: 72.32  E-value: 8.29e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 123 KIHLAVDSGGLPV-YYELSCGNTHDIVHAESLVANCPT-SNMVVADKGYDSEKLRAFVRDNNATPVIP-RKGNSLVG--- 196
Cdd:NF033579 141 KVHLAVDVKTGEIlAVEVTTNKVHDAKVLPDLLRQIPEdIDSVLADGAYDTKKCHEAIRERGARPLIPpRKNARLWKegk 220
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 639340887 197 --NEDID------------WCMYKYRHLVENAFGRIKQYRGiatryEKLE-RNYHSM 238
Cdd:NF033579 221 arNAAIReirrlgrelwkkWSGYHRRSLVETAFSRLKRLLG-----ERLRaRNFDRQ 272
transpos_IS5_4 NF033581
IS5 family transposase;
44-244 4.39e-14

IS5 family transposase;


Pssm-ID: 468098 [Multi-domain]  Cd Length: 284  Bit Score: 70.04  E-value: 4.39e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887  44 GIPWRDLPSDfgrwSAIYRRFNLWSKKGILNELFRALSRDADM------DWVFIDGSIVRA-HQHSCGARTADNESIGKS 116
Cdd:NF033581  70 GLSEDDVPDA----STIWRFRELLEEHLLAEALFAEVNRQLLAkgllskEGVIVDATLIPApRSPKKRDKKRDPDMRQTK 145
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 117 RGGNST---KIHLAVDS-GGLPVYYELSCGNTHDIVHAESLVANcpTSNMVVADKGYDSEKLRAFVRDNNATPVIPRKG- 191
Cdd:NF033581 146 KGKKSRhgyKAHIGVDPkSGLVHSLVTTPANVHDSRAAKELLHG--DEKTVYADKGYDGDEGYQGLREAGVKPHIPRKKs 223
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 639340887 192 -NSLVGNEDIdwCMYKY----RHLVENAFGRIKQYRGIA-TRYEKLERNYHSMLALAFT 244
Cdd:NF033581 224 rNRPLTEAQK--RRNRLkskiRARVEHVFGVLKRFFGLSkVRYRGLKRVGARFNLIAAL 280
transpos_IS982 NF033520
IS982 family transposase; Currently, there are 46 seed sequences in this family.
61-236 1.84e-11

IS982 family transposase; Currently, there are 46 seed sequences in this family.


Pssm-ID: 468056 [Multi-domain]  Cd Length: 243  Bit Score: 62.25  E-value: 1.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887  61 YRRFN------LWSKKGILNELFRALSRDADMdWVFIDGS------IVRAHQHSCGARTADnesIGKSRGGNST----KI 124
Cdd:NF033520  41 YSRFNrrcrrlLPLIEAIRQELAKKTKSEETG-IAIIDSTpipvchNKRIKRHKVFKGIAD---RGYCASKKGWfygfKL 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 125 HLAVDSGGLPVYYELSCGNTHDIVHAESLVANCPTSNMVVADKGYDSEKLRAFVRDNNATPVIPRKGNSLVGNEDI-DWC 203
Cdd:NF033520 117 HLLVNLSGEIVSYVITPANVHDRKVLEDLLLTKPLPGKLFGDKGYISKELQEKLKEQGITLITPLRKNMKEKLEKPnDKL 196
                        170       180       190
                 ....*....|....*....|....*....|...
gi 639340887 204 MYKYRHLVENAFGRIKQYRGIatryeklERNYH 236
Cdd:NF033520 197 LLRKRKRIETVFSQLKNQFGI-------EHSRA 222
DDE_Tnp_1_2 pfam13586
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
163-248 4.06e-10

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.


Pssm-ID: 463928 [Multi-domain]  Cd Length: 90  Bit Score: 55.12  E-value: 4.06e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887  163 VVADKGYDSEKLRAFVRDNNATPVIP---RKGNSLVGNEDIDWCMYKYRHLVENAFGRIKQYRGIATRYEKLERNYHSML 239
Cdd:pfam13586   1 VHVDRGYRTRHNREWLKERGIRASGPplgRPAKNKAQEKKQAREDEIARNVIEGKFGWFKRRRSLAKRYEKLASTFEGAI 80

                  ....*....
gi 639340887  240 ALAFTMMWL 248
Cdd:pfam13586  81 ALTFLVINL 89
IS5 COG3039
Transposase and inactivated derivatives, IS5 family [Mobilome: prophages, transposons];
123-244 1.93e-09

Transposase and inactivated derivatives, IS5 family [Mobilome: prophages, transposons];


Pssm-ID: 442273 [Multi-domain]  Cd Length: 316  Bit Score: 56.80  E-value: 1.93e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 123 KIHLAVDSG-GLPVYYELSCGNTHDIVHAESLVANcpTSNMVVADKGYDSEKLRAFVRDNNATPVI---PRKGNSLVGNE 198
Cdd:COG3039  178 KAHIGVDADsGLIHTVVTTAANVHDVTHLDELLHG--EETDVYADKGYQGAEKREELKARGIRWHIarkPGRNKPLSELQ 255
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 639340887 199 D-IDWCMYKYRHLVENAFGRIK-QYRGIATRYEKLERNYHSMLALAFT 244
Cdd:COG3039  256 KrRNRRKAKVRAKVEHPFGVIKrLFGYKKVRYRGLAKNTAQLFLLAAL 303
transpos_IS4_1 NF033592
IS4 family transposase;
58-169 1.38e-06

IS4 family transposase;


Pssm-ID: 468101 [Multi-domain]  Cd Length: 332  Bit Score: 48.41  E-value: 1.38e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887  58 SAIYRRFNLwSKKGILNELFRALSR-------DADMDWVF-----IDGSIVRAHQHSCGARTAdnesigkSRGGNST--- 122
Cdd:NF033592  67 SALSKARKR-LPVEFLKELFERLLAqlqlgqlLPRKLWRGlrvlaVDGTTIRLPDSLENWAPG-------RGGKNSFpgv 138
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 639340887 123 KIHLAVD-SGGLPVYYELSCGNTHDIVHAESLVANCPTSNMVVADKGY 169
Cdd:NF033592 139 KLHLLYDlLSGLPLDAAITPGKTHERTLLRQLLETLPPGDLLLFDRGY 186
transpos_IS1182 NF033551
IS1182 family transposase; Members of this family are transposases of the IS1182 family. ...
123-188 6.47e-06

IS1182 family transposase; Members of this family are transposases of the IS1182 family. About two-thirds of the members of this family have an extra domain between the middle and the C-terminal domain, about 50 amino acids in size and containing four invariant Cys residues.


Pssm-ID: 468080 [Multi-domain]  Cd Length: 437  Bit Score: 46.55  E-value: 6.47e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 639340887 123 KIHLAVDS-GGLPVYYELSCGNTHD----IVHAESLVANC---PTSnmVVADKGYDSEKLRAFVRDNNATPVIP 188
Cdd:NF033551 219 NVQIAVDTeSGLIVAVEVTPGNGHDggqlIPLLEQVEERLgllPEE--VLADAGYGSEENLEALEERGIEPVIP 290
COG5421 COG5421
Transposase [Mobilome: prophages, transposons];
126-233 7.90e-05

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 444174 [Multi-domain]  Cd Length: 490  Bit Score: 43.42  E-value: 7.90e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887 126 LAVDSGGLPVYYELSCGNTHDIVHAESLVAN-----CPTSNMVVADKGYDSEKLRAFVRDNNA---TPVIPRKGNSLVGN 197
Cdd:COG5421  157 LLVDRDGIPLAYEVFPGNTADVKTLKPVLEKlkkrfGLKKVILVADRGLYSEDNLALLEEAGLkfiTRLPLKEAKELLKD 236
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 639340887 198 EDIDWCMYKYRHLVENA-----FGRIKQY-----------RGIATRYEKLER 233
Cdd:COG5421  237 AILDPSNFEEGEGYRVYekeveYGGGEQRlvvvysparakKDRKTREKKLEK 288
DDE_Tnp_4 pfam13359
DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are ...
117-220 9.85e-03

DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.


Pssm-ID: 463855 [Multi-domain]  Cd Length: 158  Bit Score: 35.72  E-value: 9.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639340887  117 RGGNSTKIHLAVDSGGLPVYYELSC-GNTHDIVHAES------LVANCPTSNMVVADKGYDseklrafVRDNNATPVIPR 189
Cdd:pfam13359  25 KHHNTLKVLIVVTPNGKIIFVSKGYpGSVSDKSILENsgllkaLNLAFGPGDYILADKGFP-------ISDWLLVPYKKP 97
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 639340887  190 KGNSL-----VGNEDIDwcmyKYRHLVENAFGRIKQ 220
Cdd:pfam13359  98 GGAQLspeevEFNRRIA----SARIHVERVIGRLKG 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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