|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
1-789 |
0e+00 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 1643.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 1 MVEYVVSLDKLGVHDVEHVGGKNSSLGEMISNLAGAGVSVPGGFATTAQAYRDFLELSGLNDQIHAALDTLDVDDVNALA 80
Cdd:PRK06464 3 MMKYVLWFEELGMEDVPLVGGKNASLGEMISNLSGAGVPVPPGFATTAEAYRYFLEQTGLNEKIYELLDGLDVDDVDALA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 81 RTGAQIRQWIMEAEFPEKLNAEIRTAFAELSAGNPNLAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFA 160
Cdd:PRK06464 83 KAGAQIRQLIIDTPFPPDLEQEIREAYAKLSAGYGEASVAVRSSATAEDLPDASFAGQQETFLNVRGIDDVLEAVKECFA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 161 SLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHK 240
Cdd:PRK06464 163 SLFTDRAISYRVHQGFDHFKVALSAGVQKMVRSDLAASGVMFTLDTESGFRDVVFITASWGLGEMVVQGAVNPDEFYVHK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 241 DTLAAGRPAILRRNLGSKAIKMIYGEEASAGksVKVIDVEPADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKDG 320
Cdd:PRK06464 243 PTLKAGKPAIVRRTLGSKKIKMVYDDGGEHG--VKTVDVPEEERNRFSLTDEEVLELAKQAVIIEKHYGRPMDIEWAKDG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 321 DDGKLYIVQARPETVKSRASANVMERYLLKETGKVLVEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEP 400
Cdd:PRK06464 321 DDGKLYIVQARPETVKSRKEANVLERYKLKGQGKVLVEGRAIGPGIGSGKVRVILDISEMDKVQPGDVLVTDMTDPDWEP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 401 VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTVSCAEGDTGYIFEGELGFDIKTNSVDAMPDLP 480
Cdd:PRK06464 401 VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVLKDGQEVTVSCAEGDTGYVYEGLLEFEVEEVSLEEMPETP 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 481 FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYSVLPPEIKDSVDKRIAGYDDPVGFYVEKLVEGI 560
Cdd:PRK06464 481 TKIMMNVGNPERAFDFAALPNDGVGLARLEFIINNMIGVHPLALLEFDQQDADLKAEIEELTAGYASPEEFYVDKLAEGI 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 561 STLAAAFTPKKVIVRLSDFKSNEYANLIGGKLYEPEEENPMLGFRGASRYISENFRDCFELECRALKRVREEMGLTNVEI 640
Cdd:PRK06464 561 ATVAAAFYPKPVIVRLSDFKSNEYANLIGGERYEPEEENPMLGFRGASRYLSESFREAFALECEAIKRVREEMGLTNVEV 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 641 MVPFVRTLGEASQVIDLLAANGLKRGENGLRIIMMCELPSNAILADEFLEYFDGFSIGSNDLTQLTLGLDRDSGVIAHLF 720
Cdd:PRK06464 641 MIPFVRTVEEAEKVIELLAENGLKRGENGLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGLVAHLF 720
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639484815 721 DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLARWLMDQGIESVSLNPDSVLETWFFLAEAQA 789
Cdd:PRK06464 721 DERNPAVKKLISMAIKAAKKAGKYVGICGQAPSDHPDFAEWLVEEGIDSISLNPDAVVDTWLAVAEVEK 789
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
4-789 |
0e+00 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 1272.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 4 YVVSLDKLGVHDVEHVGGKNSSLGEMISNLAGAGVSVPGGFATTAQAYRDFLELSGLNDQIHAALDTLDVDDVNALARTG 83
Cdd:TIGR01418 1 LILWLEEVRKDDVPLVGGKNASLGEMIQNLSPAGVPVPPGFVVTAEAYRYFLEENGIAQKIRDLLEELDVEDVDALAAAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 84 AQIRQWIMEAEFPEKLNAEIRTAFAELSA--GNPNLAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFAS 161
Cdd:TIGR01418 81 AEIRELILNTPFPPDLEEAIREAYDKLSEdyGKEEADVAVRSSATAEDLPDASFAGQQETYLNVTGEEEVLEHVKKCWAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 162 LFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHKD 241
Cdd:TIGR01418 161 LFTDRAISYRVSQGFDHEKVAIAVGVQKMVRSDLGSSGVMFTIDTETGFKDAVFIESAWGLGEAVVGGAVTPDEYVVFKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 242 TLAAGRPAILRRNLGSKAIKMIYGEEASaGKSVKVIDVEPADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKDGD 321
Cdd:TIGR01418 241 TLEQGKKAILERTLGSKKIKMVYDPDGG-GVETKIVEVPEEERDAFSLSDEEILELAKLAVLIEKHYGRPMDIEWAKDGF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 322 DGKLYIVQARPETVKSRASA-NVMERYLLKETGKVLVEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEP 400
Cdd:TIGR01418 320 DGEIFIVQARPETVQSRKKKeNVEERYELKGKGKVLVTGRAAGPGIASGKVKVIFDLKEMDKFEEGDILVTDMTDPDWEP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 401 VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTVSCAEGDTGYIFEGELGFDIKTNSVDAMPDLP 480
Cdd:TIGR01418 400 AMKRASAIVTNEGGMTCHAAIVARELGIPAVVGTGDATKTLKDGMEVTVDCAEGDTGYVYAGKLEHEVKEVELSNMPVTA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 481 FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYSVLPPEIKDSVDKRIAGydDPVGFYVEKLVEGI 560
Cdd:TIGR01418 480 TKIYMNVGNPEVAFRFAALPNDGVGLARIEFIILNWIGKHPLALIDDDDLESVEKNEIEELMAG--NPRDFFVDKLAEGI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 561 STLAAAFTPKKVIVRLSDFKSNEYANLIGGKLYEPEEENPMLGFRGASRYISENFRDCFELECRALKRVREEMGLTNVEI 640
Cdd:TIGR01418 558 AKVAAAFYPKPVIVRTSDFKSNEYRNLIGGEEYEPDEENPMLGWRGASRYYSESYEEAFRLECRAIKRVREEMGLTNVEV 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 641 MVPFVRTLGEASQVIDLLAANGLKRGENGLRIIMMCELPSNAILADEFLEYFDGFSIGSNDLTQLTLGLDRDSGVIAHLF 720
Cdd:TIGR01418 638 MIPFVRTPEEGKRALEIMAEEGLRRGKNGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDRDSGLVAHLF 717
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639484815 721 DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLARWLMDQGIESVSLNPDSVLETWFFLAEAQA 789
Cdd:TIGR01418 718 DERNPAVLRLIEMAIKAAKEHGKKVGICGQAPSDYPEVVEFLVEEGIDSISLNPDAVLRTRLQVAEVEK 786
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
1-459 |
0e+00 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 671.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 1 MVEYVVSLDKLGVHDVEHVGGKNSSLGEMISnlagAGVSVPGGFATTAQAYRDFLELSGLNDQIHAALDTLDVDDVNALA 80
Cdd:COG0574 1 MTKYVYWFAEGGADDVDLVGGKGANLGEMTR----LGLPVPPGFTITTEAYRRFLEENGLEEEIRELLADLDVDDVDALA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 81 RTGAQIRQWIMEAEFPEKLNAEIRTAFAELSAG-NPNLAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVF 159
Cdd:COG0574 77 EASAEIRELILEAPLPEELEEEILAAYAKLEEKfGEDLLVAVRSSATAEDLPDASFAGQMDTVLNVNGNEQLLEAIKAVF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 160 ASLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVH 239
Cdd:COG0574 157 ASLFTDRAIAYRRHNGIDHDDVGTAVNVQAMVFGNMSASGVMFTRDPSTGEKDVVYIEALNGLGEDVVAGIVTPDPYYVD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 240 KDTlaagrpaILRRNLGSKAIKMIYGEeasagkSVKVIDVEPADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKd 319
Cdd:COG0574 237 KPT-------ILERTLGSKAIKMVYDG------GTVEVPVPPEERNRPSLTDEEYLELARIALRLEKHYGDPQDIEWAI- 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 320 gDDGKLYIVQARPETVKS---------RASANVMERYLL-------KETGKVLVEGRAIGQRIGAGKVRIIKDVSEMDKV 383
Cdd:COG0574 303 -DDGKLYILQTRPITVLEglitkeallRVDPAQLDQLLHprfdpkaKEEGEVLAKGLPASPGAASGKVVFIADEAELARF 381
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639484815 384 QPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTVscaEGDTGYI 459
Cdd:COG0574 382 QEGVILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEITV---DGTTGEV 454
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
16-351 |
6.04e-163 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 474.77 E-value: 6.04e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 16 VEHVGGKNSSLGEMisnLAGAGVSVPGGFATTAQAYRDFLELSGLNDQIHAALDTLDVDDVNALARTGAQIRQWIMEAEF 95
Cdd:pfam01326 1 VNLVGGKGANLGEM---LNDAGIPVPPGFAITADAYREFLEENGLREKIDELLKDLDVDDVDELREASKEIRQLILSAPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 96 PEKLNAEIRTAFAELSA--GNPNLAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFASLFNDRAISYRVH 173
Cdd:pfam01326 78 PEELEEAIREAYEELGKkfGDEPLPVAVRSSATAEDLPDASFAGQQDTYLNVGGNDEVLEAIKAVFASLFNDRAIAYRRE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 174 QGFDHKLVALSAGVQRMVRSEtgTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHKDTLaagrpAILRR 253
Cdd:pfam01326 158 KGIDHEDVALAVGVQRMVRSD--ASGVMFSRDPETGFRDEVLINASWGLGEAVVQGRVTPDEFYVFKPTL-----EILRR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 254 NLGSKAIKMIYGEEASAgksVKVIDVEPADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKDGDDGKLYIVQARPE 333
Cdd:pfam01326 231 TIGEKEIKMVYDEGGEG---TKEVEVPEEKRERFSLSDEEVLELARIAKKIEKHYGTPMDIEWAIDGRDGKLYILQARPE 307
|
330
....*....|....*....
gi 639484815 334 TVKSRASA-NVMERYLLKE 351
Cdd:pfam01326 308 TVWSEAMEkIAAEILEEGL 326
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
1-789 |
0e+00 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 1643.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 1 MVEYVVSLDKLGVHDVEHVGGKNSSLGEMISNLAGAGVSVPGGFATTAQAYRDFLELSGLNDQIHAALDTLDVDDVNALA 80
Cdd:PRK06464 3 MMKYVLWFEELGMEDVPLVGGKNASLGEMISNLSGAGVPVPPGFATTAEAYRYFLEQTGLNEKIYELLDGLDVDDVDALA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 81 RTGAQIRQWIMEAEFPEKLNAEIRTAFAELSAGNPNLAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFA 160
Cdd:PRK06464 83 KAGAQIRQLIIDTPFPPDLEQEIREAYAKLSAGYGEASVAVRSSATAEDLPDASFAGQQETFLNVRGIDDVLEAVKECFA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 161 SLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHK 240
Cdd:PRK06464 163 SLFTDRAISYRVHQGFDHFKVALSAGVQKMVRSDLAASGVMFTLDTESGFRDVVFITASWGLGEMVVQGAVNPDEFYVHK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 241 DTLAAGRPAILRRNLGSKAIKMIYGEEASAGksVKVIDVEPADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKDG 320
Cdd:PRK06464 243 PTLKAGKPAIVRRTLGSKKIKMVYDDGGEHG--VKTVDVPEEERNRFSLTDEEVLELAKQAVIIEKHYGRPMDIEWAKDG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 321 DDGKLYIVQARPETVKSRASANVMERYLLKETGKVLVEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEP 400
Cdd:PRK06464 321 DDGKLYIVQARPETVKSRKEANVLERYKLKGQGKVLVEGRAIGPGIGSGKVRVILDISEMDKVQPGDVLVTDMTDPDWEP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 401 VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTVSCAEGDTGYIFEGELGFDIKTNSVDAMPDLP 480
Cdd:PRK06464 401 VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVLKDGQEVTVSCAEGDTGYVYEGLLEFEVEEVSLEEMPETP 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 481 FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYSVLPPEIKDSVDKRIAGYDDPVGFYVEKLVEGI 560
Cdd:PRK06464 481 TKIMMNVGNPERAFDFAALPNDGVGLARLEFIINNMIGVHPLALLEFDQQDADLKAEIEELTAGYASPEEFYVDKLAEGI 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 561 STLAAAFTPKKVIVRLSDFKSNEYANLIGGKLYEPEEENPMLGFRGASRYISENFRDCFELECRALKRVREEMGLTNVEI 640
Cdd:PRK06464 561 ATVAAAFYPKPVIVRLSDFKSNEYANLIGGERYEPEEENPMLGFRGASRYLSESFREAFALECEAIKRVREEMGLTNVEV 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 641 MVPFVRTLGEASQVIDLLAANGLKRGENGLRIIMMCELPSNAILADEFLEYFDGFSIGSNDLTQLTLGLDRDSGVIAHLF 720
Cdd:PRK06464 641 MIPFVRTVEEAEKVIELLAENGLKRGENGLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGLVAHLF 720
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639484815 721 DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLARWLMDQGIESVSLNPDSVLETWFFLAEAQA 789
Cdd:PRK06464 721 DERNPAVKKLISMAIKAAKKAGKYVGICGQAPSDHPDFAEWLVEEGIDSISLNPDAVVDTWLAVAEVEK 789
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
4-789 |
0e+00 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 1272.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 4 YVVSLDKLGVHDVEHVGGKNSSLGEMISNLAGAGVSVPGGFATTAQAYRDFLELSGLNDQIHAALDTLDVDDVNALARTG 83
Cdd:TIGR01418 1 LILWLEEVRKDDVPLVGGKNASLGEMIQNLSPAGVPVPPGFVVTAEAYRYFLEENGIAQKIRDLLEELDVEDVDALAAAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 84 AQIRQWIMEAEFPEKLNAEIRTAFAELSA--GNPNLAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFAS 161
Cdd:TIGR01418 81 AEIRELILNTPFPPDLEEAIREAYDKLSEdyGKEEADVAVRSSATAEDLPDASFAGQQETYLNVTGEEEVLEHVKKCWAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 162 LFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHKD 241
Cdd:TIGR01418 161 LFTDRAISYRVSQGFDHEKVAIAVGVQKMVRSDLGSSGVMFTIDTETGFKDAVFIESAWGLGEAVVGGAVTPDEYVVFKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 242 TLAAGRPAILRRNLGSKAIKMIYGEEASaGKSVKVIDVEPADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKDGD 321
Cdd:TIGR01418 241 TLEQGKKAILERTLGSKKIKMVYDPDGG-GVETKIVEVPEEERDAFSLSDEEILELAKLAVLIEKHYGRPMDIEWAKDGF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 322 DGKLYIVQARPETVKSRASA-NVMERYLLKETGKVLVEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEP 400
Cdd:TIGR01418 320 DGEIFIVQARPETVQSRKKKeNVEERYELKGKGKVLVTGRAAGPGIASGKVKVIFDLKEMDKFEEGDILVTDMTDPDWEP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 401 VMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTVSCAEGDTGYIFEGELGFDIKTNSVDAMPDLP 480
Cdd:TIGR01418 400 AMKRASAIVTNEGGMTCHAAIVARELGIPAVVGTGDATKTLKDGMEVTVDCAEGDTGYVYAGKLEHEVKEVELSNMPVTA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 481 FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLNYSVLPPEIKDSVDKRIAGydDPVGFYVEKLVEGI 560
Cdd:TIGR01418 480 TKIYMNVGNPEVAFRFAALPNDGVGLARIEFIILNWIGKHPLALIDDDDLESVEKNEIEELMAG--NPRDFFVDKLAEGI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 561 STLAAAFTPKKVIVRLSDFKSNEYANLIGGKLYEPEEENPMLGFRGASRYISENFRDCFELECRALKRVREEMGLTNVEI 640
Cdd:TIGR01418 558 AKVAAAFYPKPVIVRTSDFKSNEYRNLIGGEEYEPDEENPMLGWRGASRYYSESYEEAFRLECRAIKRVREEMGLTNVEV 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 641 MVPFVRTLGEASQVIDLLAANGLKRGENGLRIIMMCELPSNAILADEFLEYFDGFSIGSNDLTQLTLGLDRDSGVIAHLF 720
Cdd:TIGR01418 638 MIPFVRTPEEGKRALEIMAEEGLRRGKNGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDRDSGLVAHLF 717
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 639484815 721 DERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPDLARWLMDQGIESVSLNPDSVLETWFFLAEAQA 789
Cdd:TIGR01418 718 DERNPAVLRLIEMAIKAAKEHGKKVGICGQAPSDYPEVVEFLVEEGIDSISLNPDAVLRTRLQVAEVEK 786
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
1-459 |
0e+00 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 671.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 1 MVEYVVSLDKLGVHDVEHVGGKNSSLGEMISnlagAGVSVPGGFATTAQAYRDFLELSGLNDQIHAALDTLDVDDVNALA 80
Cdd:COG0574 1 MTKYVYWFAEGGADDVDLVGGKGANLGEMTR----LGLPVPPGFTITTEAYRRFLEENGLEEEIRELLADLDVDDVDALA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 81 RTGAQIRQWIMEAEFPEKLNAEIRTAFAELSAG-NPNLAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVF 159
Cdd:COG0574 77 EASAEIRELILEAPLPEELEEEILAAYAKLEEKfGEDLLVAVRSSATAEDLPDASFAGQMDTVLNVNGNEQLLEAIKAVF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 160 ASLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVH 239
Cdd:COG0574 157 ASLFTDRAIAYRRHNGIDHDDVGTAVNVQAMVFGNMSASGVMFTRDPSTGEKDVVYIEALNGLGEDVVAGIVTPDPYYVD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 240 KDTlaagrpaILRRNLGSKAIKMIYGEeasagkSVKVIDVEPADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKd 319
Cdd:COG0574 237 KPT-------ILERTLGSKAIKMVYDG------GTVEVPVPPEERNRPSLTDEEYLELARIALRLEKHYGDPQDIEWAI- 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 320 gDDGKLYIVQARPETVKS---------RASANVMERYLL-------KETGKVLVEGRAIGQRIGAGKVRIIKDVSEMDKV 383
Cdd:COG0574 303 -DDGKLYILQTRPITVLEglitkeallRVDPAQLDQLLHprfdpkaKEEGEVLAKGLPASPGAASGKVVFIADEAELARF 381
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639484815 384 QPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTVscaEGDTGYI 459
Cdd:COG0574 382 QEGVILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEITV---DGTTGEV 454
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
16-351 |
6.04e-163 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 474.77 E-value: 6.04e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 16 VEHVGGKNSSLGEMisnLAGAGVSVPGGFATTAQAYRDFLELSGLNDQIHAALDTLDVDDVNALARTGAQIRQWIMEAEF 95
Cdd:pfam01326 1 VNLVGGKGANLGEM---LNDAGIPVPPGFAITADAYREFLEENGLREKIDELLKDLDVDDVDELREASKEIRQLILSAPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 96 PEKLNAEIRTAFAELSA--GNPNLAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFASLFNDRAISYRVH 173
Cdd:pfam01326 78 PEELEEAIREAYEELGKkfGDEPLPVAVRSSATAEDLPDASFAGQQDTYLNVGGNDEVLEAIKAVFASLFNDRAIAYRRE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 174 QGFDHKLVALSAGVQRMVRSEtgTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHKDTLaagrpAILRR 253
Cdd:pfam01326 158 KGIDHEDVALAVGVQRMVRSD--ASGVMFSRDPETGFRDEVLINASWGLGEAVVQGRVTPDEFYVFKPTL-----EILRR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 254 NLGSKAIKMIYGEEASAgksVKVIDVEPADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKDGDDGKLYIVQARPE 333
Cdd:pfam01326 231 TIGEKEIKMVYDEGGEG---TKEVEVPEEKRERFSLSDEEVLELARIAKKIEKHYGTPMDIEWAIDGRDGKLYILQARPE 307
|
330
....*....|....*....
gi 639484815 334 TVKSRASA-NVMERYLLKE 351
Cdd:pfam01326 308 TVWSEAMEkIAAEILEEGL 326
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
1-334 |
2.05e-96 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 319.53 E-value: 2.05e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 1 MVEYVVSLDKLGVHDVEHVGGKNSSLGEMiSNlagAGVSVPGGFATTAQAYRDFLELSGLNDQIHAALDTLDVDDVNALA 80
Cdd:PRK06241 1 MSSYVLDFQEIDKTQLPLVGGKGANLGEL-SR---AGIPVPEGFCVTTEAYKKFLEQNEEFDALLDQLSALKLEDREQIG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 81 RTGAQIRQWIMEAEFPEKLNAEIRTAFAELSAGNpnlAVAVRSSATAEDLPDASFAGQQETFLNIRGVENVIRAAKEVFA 160
Cdd:PRK06241 77 EISAKIREVIEAIEIPEDIVEAIAAALSKFGEDH---AYAVRSSATAEDLPTASFAGQQDTYLNVIGKDAILQHIRKCWA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 161 SLFNDRAISYRVHQGFDHKLVALSAGVQRMVRSEtgTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHK 240
Cdd:PRK06241 154 SLFTERAVIYRIQNGFDHRKVYMSVVVQKMVFPE--ASGIMFTADPVTGNRKVLSIDASFGLGEALVSGLVSADTYKVRE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 241 DTlaagrpaILRRNLGSKAIkMIYgeeASAGKSVKVIDVEPADRARFCLTDAEVSELAKQAMIIEKHYKCPMDIEWAKdg 320
Cdd:PRK06241 232 GK-------IIDKTIATKKL-AIY---ALKEGGTETKEIEPEQQKSQTLTDEQILELARLGRKIEAHFGCPQDIEWCL-- 298
|
330
....*....|....
gi 639484815 321 DDGKLYIVQARPET 334
Cdd:PRK06241 299 ADGTFYILQSRPIT 312
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
481-778 |
2.26e-65 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 219.49 E-value: 2.26e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 481 FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIInrmigvhpkalLNYSVLPpeikdsvdkriagyddpvgfYVEKLVEGI 560
Cdd:pfam02896 20 IKVAANIGTPDDAEAALANGAEGIGLYRTEFLF-----------MDRDELP--------------------TEDEQFEAY 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 561 STLAAAFTPKKVIVRLSDFKSNEYanLIGGklYEPEEENPMLGFRGASRYISEnfRDCFELECRALKRVREEMgltNVEI 640
Cdd:pfam02896 69 KGVLEAMNGRPVTVRTLDIGGDKE--LPYL--EEPEEMNPFLGWRGIRIGLDR--PELFRTQLRAILRASAFG---NLRI 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 641 MVPFVRTLGEASQVIDLLAANGLKRGEN-----GLRIIMMCELPSNAILADEFLEYFDGFSIGSNDLTQLTLGLDRDSGV 715
Cdd:pfam02896 140 MFPMVASVEELREAKAIIEEVKEELDAEvgfdkDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNER 219
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639484815 716 IAHLFDERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDhPDLARWLMDQGIESVSLNPDSVL 778
Cdd:pfam02896 220 VAYLYDPLHPAVLRLIKEVIRAAHRHGKWVGICGEMAGD-PSAVPLLVGLGLDEFSMSPDSVP 281
|
|
| PtsA |
COG1080 |
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ... |
360-780 |
2.50e-50 |
|
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];
Pssm-ID: 440698 [Multi-domain] Cd Length: 571 Bit Score: 186.05 E-value: 2.50e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 360 RAIGQRIgagkVRIIKDVSEMD--KVQPGDVLV------SDMT--DPdwepvmKRASAIVTNRGGRTCHAAIIARELGIP 429
Cdd:COG1080 130 RDVGRRV----LRNLLGVEAPDlsDLPEPVILVahdltpSDTAqlDP------SRVAGFVTDLGGRTSHTAILARSLGIP 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 430 AVVGCGNATHTLQDGQGVTVscaEGDTGYIF----EGEL--------GFDIKTNSVDAMPDLP--------FKIMMNVGN 489
Cdd:COG1080 200 AVVGLGDALLLVKDGDLVIV---DGDAGVVIvnpdEETLaeyrerqaEYAAERAELARLRDLPavtldgvrVELAANIGL 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 490 PDrafDFAQLPNA---GVGLARLEFIinrmigvhpkaLLNYSVLPPEikdsvdkriagyddpvgfyvEKLVEGISTLAAA 566
Cdd:COG1080 277 PE---DAAAALENgaeGVGLFRTEFL-----------FMDRDDLPTE--------------------EEQFEAYRAVAEA 322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 567 FTPKKVIVRLSDfksneyanlIGG-K----LYEPEEENPMLGFRGAsRYiSENFRDCFELECRALKRVREEmglTNVEIM 641
Cdd:COG1080 323 MGGRPVTIRTLD---------IGGdKplpyLPLPKEENPFLGLRAI-RL-CLDRPELFRTQLRAILRASAH---GNLRIM 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 642 VPFVRTLGEASQVIDL-------LAANGLKRGENgLRIIMMCELPSNAILADEFLEYFDGFSIGSNDLTQLTLGLDRDSG 714
Cdd:COG1080 389 FPMISSVEELRQAKALleeakaeLRAEGIPFDED-IPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNE 467
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639484815 715 VIAHLFDERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDhPDLARWLMDQGIESVSLNPDSVLET 780
Cdd:COG1080 468 KVAYLYDPLHPAVLRLIKMVIDAAHKAGKPVGVCGEMAGD-PLATPLLLGLGLDELSMSPSSIPAV 532
|
|
| PTS_I_fam |
TIGR01417 |
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ... |
409-778 |
2.00e-36 |
|
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.
Pssm-ID: 273611 [Multi-domain] Cd Length: 565 Bit Score: 145.32 E-value: 2.00e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 409 VTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTVSCAEGdtgyifegELGFDIKTNSVDA------------- 475
Cdd:TIGR01417 179 LTDAGGKTSHTAIMARSLEIPAIVGTKSVTSQVKNGDTVIIDGVKG--------IVIFNPSSETIDKyeakqeavsseka 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 476 ----MPDLPFK--------IMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRmigvhpkallnySVLPPeikdSVDKRIA 543
Cdd:TIGR01417 251 elakLKDKPAItldghqveLAANIGTVDDVEGAERNGGEGIGLFRTEFLYMS------------RDQLP----TEEEQFA 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 544 GYddpvgfyveklvegiSTLAAAFTPKKVIVRLSDF---KSNEYANLiggklyePEEENPMLGFRgASRYISENfRDCFE 620
Cdd:TIGR01417 315 AY---------------KTVLEAMESDAVIVRTLDIggdKELPYLNF-------PKEENPFLGYR-AIRLALER-EEILR 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 621 LECRALKRVREEmglTNVEIMVPFVRTLGEASQV-------IDLLAANGLKRGENgLRIIMMCELPSNAILADEFLEYFD 693
Cdd:TIGR01417 371 TQLRAILRASAY---GKLRIMFPMVATVEEIRAVkqeleeeKQELNDEGKAFDEN-IEVGVMIEIPSAALIADHLAKEVD 446
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 694 GFSIGSNDLTQLTLGLDRDSGVIAHLFDERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDHPdLARWLMDQGIESVSLN 773
Cdd:TIGR01417 447 FFSIGTNDLTQYTLAVDRGNDLISNLYQPYNPAVLRLIKLVIDAAKAEGIWVGMCGEMAGDER-AIPLLLGLGLRELSMS 525
|
....*
gi 639484815 774 PDSVL 778
Cdd:TIGR01417 526 ASSIL 530
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
353-463 |
2.98e-33 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 130.79 E-value: 2.98e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 353 GKVLVEGRAIGQRIGAGKVRIIKDVSE-MDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAV 431
Cdd:COG3848 209 GDVLAKGQGIGRGSVTGKAVVARSAEEaLEKFEEGDILVVPSTDAEFVPAIEKAAGIITEEGGLTSHAAIVGLELGIPVI 288
|
90 100 110
....*....|....*....|....*....|..
gi 639484815 432 VGCGNATHTLQDGQGVTVscaEGDTGYIFEGE 463
Cdd:COG3848 289 VGAEGATEILKDGQVVTV---DAERGVVYRGA 317
|
|
| PEP-utilizers |
pfam00391 |
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ... |
382-454 |
3.42e-31 |
|
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.
Pssm-ID: 459796 [Multi-domain] Cd Length: 73 Bit Score: 116.36 E-value: 3.42e-31
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 639484815 382 KVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTVSCAEG 454
Cdd:pfam00391 1 KLPEGVILVAPDTTPSDTAGLDKAAGIVTERGGMTSHAAIVARELGIPAVVGVGDATILLKEGDLVTVDGSTG 73
|
|
| PRK11177 |
PRK11177 |
phosphoenolpyruvate-protein phosphotransferase PtsI; |
409-750 |
2.16e-30 |
|
phosphoenolpyruvate-protein phosphotransferase PtsI;
Pssm-ID: 183017 [Multi-domain] Cd Length: 575 Bit Score: 127.05 E-value: 2.16e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 409 VTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDG-----------------QGVTVSCAEGDTGYIFEGELGFDIKtn 471
Cdd:PRK11177 180 ITDIGGRTSHTSIMARSLELPAIVGTGNITKQVKNGdylildavnnqiyvnptNEVIEELKAVQEQYASEKAELAKLK-- 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 472 svdampDLP--------FKIMMNVGNPdRAFDFAQLPNA-GVGLARLEFIinrmigvhpkaLLNYSVLPPEikdsvdkri 542
Cdd:PRK11177 258 ------DLPaitldghqVEVCANIGTV-RDVEGAERNGAeGVGLYRTEFL-----------FMDRDALPTE--------- 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 543 agyddpvgfyvEKLVEGISTLAAAFTPKKVIVRLSDF---KSNEYANLiggklyePEEENPMLGFRgASRyISENFRDCF 619
Cdd:PRK11177 311 -----------EEQFQAYKAVAEAMGSQAVIVRTMDIggdKELPYMNL-------PKEENPFLGWR-AIR-IAMDRKEIL 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 620 ELECRALKRVReemGLTNVEIMVPF------VRTL-GEASQVIDLLAANGLKRGENgLRIIMMCELPSNAILADEFLEYF 692
Cdd:PRK11177 371 HDQLRAILRAS---AFGKLRIMFPMiisveeVRELkAEIEILKQELRDEGKAFDES-IEIGVMVETPAAAVIARHLAKEV 446
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 639484815 693 DGFSIGSNDLTQLTLGLDRDSGVIAHLFDERNPAVKKLLSNAIQACNKAGKYIGICGQ 750
Cdd:PRK11177 447 DFFSIGTNDLTQYTLAVDRGNELISHLYNPMSPSVLNLIKQVIDASHAEGKWTGMCGE 504
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
5-479 |
1.85e-25 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 111.38 E-value: 1.85e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 5 VVSLDKLGVHDVEHVGGKNSSLGEMISNlagaGVSVPGGFATTAQAYRDFLE-----LSGLNDQIHAALDTLDvddvnal 79
Cdd:PRK05878 9 VVLLDGGANQPRELLGGKGHGIDMMRRL----GLPVPPAFCITTEVCVRYLAdpgstIDAIWDDVLDRMRWLE------- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 80 ARTGaqirqwimeaefpeklnaeiRTafaeLSAGNPNLAVAVRSSAT-----------------------AEDLPDASFA 136
Cdd:PRK05878 78 AETG--------------------RT----FGRGPRPLLVSVRSGAAqsmpgmmdtilnlgindaveqalAAEGGDPDFA 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 137 GQ-----QETFLNIRGVENVI--------RAAKE-VFASLFNDRAISYRVHQGFDHKLvALSAGVQRMV---RSETGTAG 199
Cdd:PRK05878 134 ADtrrrfTEMYRRIVGSGSPPpddpyeqlRAAIEaVFASWNSPRAVAYRRHHGLDDDG-GTAVVVQAMVfgnLDANSGTG 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 200 VMFTLDTESGfRDVVFitGAY---GLGETVVQGAVNPDefyvHKDTLAAGRPAILRrnlgskaikmiygeeasagksvkv 276
Cdd:PRK05878 213 VLFSRNPITG-ANEPF--GEWlpgGQGEDVVSGLVDVA----PITALRDEQPAVYD------------------------ 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 277 idvepadrarfcltdaevsELAKQAMIIEKHYKCPMDIEWAKDgdDGKLYIVQAR-----------------------PE 333
Cdd:PRK05878 262 -------------------ELMAAARTLERLGRDVQDIEFTVE--SGKLWLLQTRsakrsaqaavrlalqlhdeglidDA 320
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 334 TVKSRASANVMERYLLKE-------TGKVLVEGRAIGQRIGAGKVriIKDVSE-MDKVQPGD--VLVSDMTDPDWEPVMK 403
Cdd:PRK05878 321 EALRRVTPTHVETLLRPSlqpearlAAPLLAKGLPACPGVVSGTA--YTDVDEaLDAADRGEpvILVRDHTRPDDVHGML 398
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 639484815 404 RASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTVscaEGDTGYIFEGELgfDIKTNSVDAMPDL 479
Cdd:PRK05878 399 AAQGIVTEVGGATSHAAVVSRELGRVAVVGCGAGVAAALAGKEITV---DGYEGEVRQGVL--ALSAWSESDTPEL 469
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
353-455 |
1.66e-24 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 108.86 E-value: 1.66e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 353 GKVLVEGRAIGQRIGAGKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVV 432
Cdd:PRK06354 479 GAVVAKGQGIGRKSVSGKARVAKTAAEVAKVNEGDILVTPSTDADMIPAIEKAAAIITEEGGLTSHAAVVGLRLGIPVIV 558
|
90 100
....*....|....*....|...
gi 639484815 433 GCGNATHTLQDGQGVTVSCAEGD 455
Cdd:PRK06354 559 GVKNATSLIKDGQIITVDAARGV 581
|
|
| PRK08296 |
PRK08296 |
hypothetical protein; Provisional |
369-459 |
3.02e-24 |
|
hypothetical protein; Provisional
Pssm-ID: 181362 Cd Length: 603 Bit Score: 108.20 E-value: 3.02e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 369 GKVRIIKDVSEMDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVT 448
Cdd:PRK08296 512 GPARVIRSADELSEVQEGEILVCPVTSPSWAPIFAKIKATVTDIGGVMSHAAIVCREYGLPAVVGTGNATKRIKTGQRLR 591
|
90
....*....|.
gi 639484815 449 VscaEGDTGYI 459
Cdd:PRK08296 592 V---DGTKGVV 599
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
357-459 |
2.13e-21 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 99.96 E-value: 2.13e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 357 VEGRAigqrigagkvRIIKDVsEMDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGN 436
Cdd:PRK06241 778 VEGRA----------RVILNP-EDADLEKGDILVTAFTDPGWTPLFVSIKGLVTEVGGLMTHGAVIAREYGIPAVVGVEN 846
|
90 100
....*....|....*....|...
gi 639484815 437 ATHTLQDGQGVTVscaEGDTGYI 459
Cdd:PRK06241 847 ATKLIKDGQRIRV---DGTEGYV 866
|
|
| PRK11061 |
PRK11061 |
phosphoenolpyruvate--protein phosphotransferase; |
403-777 |
2.49e-20 |
|
phosphoenolpyruvate--protein phosphotransferase;
Pssm-ID: 182937 [Multi-domain] Cd Length: 748 Bit Score: 96.22 E-value: 2.49e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 403 KRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVTvscaEGDTGYIF---------------------- 460
Cdd:PRK11061 341 DRLAGVVVRDGAANSHAAILVRALGIPTVMGADIQPSLLHQRLLIV----DGYRGELLvdpepvllqeyqrliseeiels 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 461 ---EGELGFDIKTNSVDAMpdlpfKIMMNVGnpdRAFDFAQLPNA---GVGLARLEFiinrmigvhpkALLNYSVLPPEi 534
Cdd:PRK11061 417 rlaEDDVNLPAQLKSGERI-----KVMLNAG---LSAEHEEKLGSrvdGVGLYRTEI-----------PFMLQSGFPSE- 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 535 kdsvDKRIAGYddpvgfyveklvEGISTLaaaFTPKKVIVRLSDfksneyanlIGG--KL-YEP-EEENPMLGFRGASry 610
Cdd:PRK11061 477 ----EEQVAQY------------QGMLQM---FPDKPVTLRTLD---------IGAdkQLpYMPiSEENPCLGWRGIR-- 526
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 611 ISENFRDCFELECRALKRVREEMGltNVEIMVPFVRTLGEASQVIDLLA-ANGLKRGENGLRIIM-----MCELPSNAIL 684
Cdd:PRK11061 527 ITLDQPEIFLIQVRAMLRANAATG--NLSILLPMVTSIDEVDEARRLIDrAGREVEEMLGYEIPKprigiMIEVPSMVFM 604
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 685 ADEFLEYFDGFSIGSNDLTQLTLGLDRDSGVIAHLFDERNPAVKKLLSNAIQACNKAGKYIGICGQGPSDhPDLARWLMD 764
Cdd:PRK11061 605 LPHLASRVDFISVGTNDLTQYLLAVDRNNTRVASLYDSLHPAMLRALKMIADEAEQHGLPVSLCGEMAGD-PMGALLLIG 683
|
410
....*....|...
gi 639484815 765 QGIESVSLNPDSV 777
Cdd:PRK11061 684 LGYRHLSMNGRSV 696
|
|
| PRK05865 |
PRK05865 |
sugar epimerase family protein; |
369-459 |
3.51e-12 |
|
sugar epimerase family protein;
Pssm-ID: 235630 [Multi-domain] Cd Length: 854 Bit Score: 70.07 E-value: 3.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 369 GKVRIIKDvSEMDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATHTLQDGQGVT 448
Cdd:PRK05865 748 GRVRIVRP-ETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVE 826
|
90
....*....|.
gi 639484815 449 VscaEGDTGYI 459
Cdd:PRK05865 827 V---DGATGEI 834
|
|
| PRK05849 |
PRK05849 |
hypothetical protein; Provisional |
107-341 |
8.49e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 235623 [Multi-domain] Cd Length: 783 Bit Score: 46.13 E-value: 8.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 107 FAELSAGNPNLAVAVRSSATAEDLPDASFAGQQETFLNIRG--VENVIRAAKEVFASLfndraisyrvHQGFDHKLVals 184
Cdd:PRK05849 46 LEEIQNSFPADKLIVRSSSRSEDSSSSSNAGAFLSILNVNAdsKDQLLKAIEKVIASY----------GTSKDDEIL--- 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639484815 185 agVQRMVRsETGTAGVMFTLDTESGFRDVVfitgayglgetvvqgaVNPDEfYVHKDTLAAGRpailrrnlGSKAIKMIY 264
Cdd:PRK05849 113 --VQPMLE-DIVLSGVAMSRDPESGAPYYV----------------INYDE-SGSTDSVTSGS--------GGSATTVYH 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639484815 265 GEEASAGKSVKVidvepadrarfcltdAEVSELAKQamiIEKHYKC-PMDIEWAKDgDDGKLYIVQARPETVKSRASA 341
Cdd:PRK05849 165 YRDALVFKPPRL---------------KKLIELIRE---LEALFGCdFLDIEFAID-EKEELYILQVRPITVPEKWNA 223
|
|
| PRK05849 |
PRK05849 |
hypothetical protein; Provisional |
395-435 |
1.04e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 235623 [Multi-domain] Cd Length: 783 Bit Score: 42.66 E-value: 1.04e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 639484815 395 DP--DWePVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCG 435
Cdd:PRK05849 717 DPgyDW-LFTKGIAGLITCYGGANSHMAIRAAELGLPAVIGVG 758
|
|
| PRK11377 |
PRK11377 |
dihydroxyacetone kinase subunit M; Provisional |
412-454 |
1.05e-03 |
|
dihydroxyacetone kinase subunit M; Provisional
Pssm-ID: 183108 [Multi-domain] Cd Length: 473 Bit Score: 42.43 E-value: 1.05e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 639484815 412 RGGRTC-HAAIIARELGIPAVVGCGNATHTLQDGQGVTVSCAEG 454
Cdd:PRK11377 424 SAGSPLsHSAIIARELGIGWICQQGEKLYAIQPEETLTLDVKTQ 467
|
|
| |
