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Conserved domains on  [gi|639685071|ref|WP_024718741|]
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MULTISPECIES: MauE/DoxX family redox-associated membrane protein [Bacillus]

Protein Classification

DoxX family protein( domain architecture ID 229470)

DoxX family protein similar to Saccharomyces cerevisiae ER-derived vesicles protein ERV29, a constituent of COPII-coated endoplasmic reticulum-derived transport vesicles

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DoxX super family cl21527
DoxX; These proteins appear to have some sequence similarity with pfam04173 but their function ...
 11-157 8.15e-12

DoxX; These proteins appear to have some sequence similarity with pfam04173 but their function is unknown.


The actual alignment was detected with superfamily member pfam07291:

Pssm-ID: 451291  Cd Length: 184  Bit Score: 60.76  E-value: 8.15e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639685071   11 LLGIIFAGAWLDKARKQKAHVQQINAYRLLPPSFAAPMFYLFLLIELVCTVHLFIWNMSVLPAIGLTALLCIYTGAVTFN 90
Cdd:pfam07291  15 FIAILFAAAAIPKFRHPDEFQGVVANFKLLPDFASAPVAKLLPLVEAACAVALMIPPAAEIAACAAAALFIVFAAALAIN 94

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639685071   91 LIRGHRDISCGC-GGLLENDRLHWGIVIRNLLMLTLVAGLFYVHPSVEMISLRLKMICFLIAAAVCLI 157
Cdd:pfam07291  95 VGRGRTHIDCGCfRNGLKMQPIGMFHVLRAIALAALALAIAAGLPAASPASIEEGAMGLAAAAMAALI 162
 
Name Accession Description Interval E-value
MauE pfam07291
Methylamine utilization protein MauE; This family consists of several bacterial methylamine ...
 11-157 8.15e-12

Methylamine utilization protein MauE; This family consists of several bacterial methylamine utilization MauE proteins. Synthesis of enzymes involved in methylamine oxidation via methylamine dehydrogenase (MADH) is encoded by genes present in the mau cluster. MauE and MauD are specifically involved in the processing, transport, and/or maturation of the beta-subunit and that the absence of each of these proteins leads to production of a non-functional beta-subunit which becomes rapidly degraded.


Pssm-ID: 399932  Cd Length: 184  Bit Score: 60.76  E-value: 8.15e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639685071   11 LLGIIFAGAWLDKARKQKAHVQQINAYRLLPPSFAAPMFYLFLLIELVCTVHLFIWNMSVLPAIGLTALLCIYTGAVTFN 90
Cdd:pfam07291  15 FIAILFAAAAIPKFRHPDEFQGVVANFKLLPDFASAPVAKLLPLVEAACAVALMIPPAAEIAACAAAALFIVFAAALAIN 94

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639685071   91 LIRGHRDISCGC-GGLLENDRLHWGIVIRNLLMLTLVAGLFYVHPSVEMISLRLKMICFLIAAAVCLI 157
Cdd:pfam07291  95 VGRGRTHIDCGCfRNGLKMQPIGMFHVLRAIALAALALAIAAGLPAASPASIEEGAMGLAAAAMAALI 162
 
Name Accession Description Interval E-value
MauE pfam07291
Methylamine utilization protein MauE; This family consists of several bacterial methylamine ...
 11-157 8.15e-12

Methylamine utilization protein MauE; This family consists of several bacterial methylamine utilization MauE proteins. Synthesis of enzymes involved in methylamine oxidation via methylamine dehydrogenase (MADH) is encoded by genes present in the mau cluster. MauE and MauD are specifically involved in the processing, transport, and/or maturation of the beta-subunit and that the absence of each of these proteins leads to production of a non-functional beta-subunit which becomes rapidly degraded.


Pssm-ID: 399932  Cd Length: 184  Bit Score: 60.76  E-value: 8.15e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639685071   11 LLGIIFAGAWLDKARKQKAHVQQINAYRLLPPSFAAPMFYLFLLIELVCTVHLFIWNMSVLPAIGLTALLCIYTGAVTFN 90
Cdd:pfam07291  15 FIAILFAAAAIPKFRHPDEFQGVVANFKLLPDFASAPVAKLLPLVEAACAVALMIPPAAEIAACAAAALFIVFAAALAIN 94

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 639685071   91 LIRGHRDISCGC-GGLLENDRLHWGIVIRNLLMLTLVAGLFYVHPSVEMISLRLKMICFLIAAAVCLI 157
Cdd:pfam07291  95 VGRGRTHIDCGCfRNGLKMQPIGMFHVLRAIALAALALAIAAGLPAASPASIEEGAMGLAAAAMAALI 162
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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