NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|640581318|ref|WP_025011517|]
View 

MULTISPECIES: hypothetical protein [Shewanella]

Protein Classification

lipase family protein( domain architecture ID 1903390)

lipase family protein such as triacylglycerol lipase, which is an alpha/beta hydrolase that catalyzes the hydrolysis of a triacylglycerol to form the corresponding diacylglycerol and a carboxylate

CATH:  3.40.50.1820
EC:  3.1.1.-
Gene Ontology:  GO:0006629|GO:0016787|GO:0016298
PubMed:  7946464|1290943
SCOP:  3000102

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
EstA super family cl43327
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
25-136 2.73e-06

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


The actual alignment was detected with superfamily member COG1075:

Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 45.21  E-value: 2.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581318  25 VAFVHGTGkQTDALNDYWTREFVDSvrqgistpsNYQVINCDFEQYMWD-EAAAGCLVDQLQSFINARNLDQLILITHSN 103
Cdd:COG1075    8 VVLVHGLG-GSAASWAPLAPRLRAA---------GYPVYALNYPSTNGSiEDSAEQLAAFVDAVLAATGAEKVDLVGHSM 77
                         90       100       110
                 ....*....|....*....|....*....|...
gi 640581318 104 GGNIVRWVLSNPTWDGRypavinsISRVIALAP 136
Cdd:COG1075   78 GGLVARYYLKRLGGAAK-------VARVVTLGT 103
 
Name Accession Description Interval E-value
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
25-136 2.73e-06

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 45.21  E-value: 2.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581318  25 VAFVHGTGkQTDALNDYWTREFVDSvrqgistpsNYQVINCDFEQYMWD-EAAAGCLVDQLQSFINARNLDQLILITHSN 103
Cdd:COG1075    8 VVLVHGLG-GSAASWAPLAPRLRAA---------GYPVYALNYPSTNGSiEDSAEQLAAFVDAVLAATGAEKVDLVGHSM 77
                         90       100       110
                 ....*....|....*....|....*....|...
gi 640581318 104 GGNIVRWVLSNPTWDGRypavinsISRVIALAP 136
Cdd:COG1075   78 GGLVARYYLKRLGGAAK-------VARVVTLGT 103
 
Name Accession Description Interval E-value
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
25-136 2.73e-06

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 45.21  E-value: 2.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581318  25 VAFVHGTGkQTDALNDYWTREFVDSvrqgistpsNYQVINCDFEQYMWD-EAAAGCLVDQLQSFINARNLDQLILITHSN 103
Cdd:COG1075    8 VVLVHGLG-GSAASWAPLAPRLRAA---------GYPVYALNYPSTNGSiEDSAEQLAAFVDAVLAATGAEKVDLVGHSM 77
                         90       100       110
                 ....*....|....*....|....*....|...
gi 640581318 104 GGNIVRWVLSNPTWDGRypavinsISRVIALAP 136
Cdd:COG1075   78 GGLVARYYLKRLGGAAK-------VARVVTLGT 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH