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Conserved domains on  [gi|640581526|ref|WP_025011718|]
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MULTISPECIES: chromosomal replication initiator protein DnaA [Shewanella]

Protein Classification

chromosomal replication initiator protein DnaA( domain architecture ID 11489097)

chromosomal replication initiator protein DnaA plays a key role in the initiation and regulation of chromosomal replication

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
6-460 0e+00

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 717.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526    6 WQQCIGRLQDELSAQQFSMWIRPLQA-EMDGDTLVIYAPNRFVLDWVRDKYLNIINQFFTEHLGNDaPKLRFDIGSRPSA 84
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLlSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAE-IEIEFTVGEDEEE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526   85 -KPQVQTPTATKASVSAPKSAagkgatfntaaepavnhsyRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPL 163
Cdd:TIGR00362  80 lEPNSKKPEPAPPEAPAPPSS-------------------ASGLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPL 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  164 FLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEDFKRYYRSVDALFIDDIQFFANKDRSQE 243
Cdd:TIGR00362 141 FIYGGVGLGKTHLLHAIGNEILENNPNAKVLYVSSEKFTNDFVNALRNNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQE 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  244 EFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKR 323
Cdd:TIGR00362 221 EFFHTFNALHENNKQIVLTSDRPPKELPGLEDRLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKN 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  324 LRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQ 403
Cdd:TIGR00362 301 ITSNVRELEGALNRLLAYASLTGKPITLELAKEALKDLLRAQKKEITIENIQKVVAKYYNIKVSDLKSKKRTRNIVRPRQ 380
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 640581526  404 MAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTL 460
Cdd:TIGR00362 381 IAMYLAKELTDLSLPEIGKAFGGRDHTTVLHAVRKIEKLIETDAELKEDIEELKRKL 437
 
Name Accession Description Interval E-value
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
6-460 0e+00

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 717.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526    6 WQQCIGRLQDELSAQQFSMWIRPLQA-EMDGDTLVIYAPNRFVLDWVRDKYLNIINQFFTEHLGNDaPKLRFDIGSRPSA 84
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLlSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAE-IEIEFTVGEDEEE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526   85 -KPQVQTPTATKASVSAPKSAagkgatfntaaepavnhsyRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPL 163
Cdd:TIGR00362  80 lEPNSKKPEPAPPEAPAPPSS-------------------ASGLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPL 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  164 FLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEDFKRYYRSVDALFIDDIQFFANKDRSQE 243
Cdd:TIGR00362 141 FIYGGVGLGKTHLLHAIGNEILENNPNAKVLYVSSEKFTNDFVNALRNNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQE 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  244 EFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKR 323
Cdd:TIGR00362 221 EFFHTFNALHENNKQIVLTSDRPPKELPGLEDRLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKN 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  324 LRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQ 403
Cdd:TIGR00362 301 ITSNVRELEGALNRLLAYASLTGKPITLELAKEALKDLLRAQKKEITIENIQKVVAKYYNIKVSDLKSKKRTRNIVRPRQ 380
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 640581526  404 MAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTL 460
Cdd:TIGR00362 381 IAMYLAKELTDLSLPEIGKAFGGRDHTTVLHAVRKIEKLIETDAELKEDIEELKRKL 437
dnaA PRK00149
chromosomal replication initiator protein DnaA;
1-462 0e+00

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 709.98  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526   1 MAVSLWQQCIGRLQDELSAQQFSMWIRPLQ-AEMDGDTLVIYAPNRFVLDWVRDKYLNIINQFFTehlgndapklrfdig 79
Cdd:PRK00149   1 NLQSLWEKVLERLKDELSEQEYETWIKPLKaLSLEDNTLTLYVPNRFVKDWIEKNYLDLIEEALQ--------------- 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  80 srpsakpqvqtptatkasvsapksaagkgatfntaaepavnhsyrsnINPTYQFDNFVEGKSNQLGKAAALQVAENPGGA 159
Cdd:PRK00149  66 -----------------------------------------------LNPKYTFDNFVVGKSNRLAHAAALAVAENPGKA 98
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 160 YNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEDFKRYYRSVDALFIDDIQFFANKD 239
Cdd:PRK00149  99 YNPLFIYGGVGLGKTHLLHAIGNYILEKNPNAKVVYVTSEKFTNDFVNALRNNTMEEFKEKYRSVDVLLIDDIQFLAGKE 178
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 240 RSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFF 319
Cdd:PRK00149 179 RTQEEFFHTFNALHEAGKQIVLTSDRPPKELPGLEERLRSRFEWGLTVDIEPPDLETRIAILKKKAEEEGIDLPDEVLEF 258
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 320 IAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVA 399
Cdd:PRK00149 259 IAKNITSNVRELEGALNRLIAYASLTGKPITLELAKEALKDLLAAQKKKITIENIQKVVAEYYNIKVSDLKSKSRTRNIA 338
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 640581526 400 RPRQMAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS 462
Cdd:PRK00149 339 RPRQIAMYLAKELTDLSLPEIGRAFGGRDHTTVLHAVRKIEKLLEEDPELKEDVEELKRKLKS 401
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
127-429 0e+00

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 548.64  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 127 INPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMV 206
Cdd:COG0593    1 LNPRYTFDNFVVGPSNRLAHAAALAVAEWPGKAYNPLFLYGGVGLGKTHLLHAIGNEALENNPGARVVYLTAEEFTNDFI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 207 KALQNNAIEDFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLT 286
Cdd:COG0593   81 NAIRNNTIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWGLV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 287 VAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQE 366
Cdd:COG0593  161 VDIQPPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLKDLLRAQK 240
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 640581526 367 KLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQMAMALSKELTNQSLPEIGDAFGGRDH 429
Cdd:COG0593  241 KEITIEDIQKAVAEYFGVSVADLLSKSRTREIARPRQIAMYLARELTDLSLPEIGRAFGGRDH 303
Bac_DnaA pfam00308
Bacterial dnaA protein;
127-345 7.26e-127

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 367.04  E-value: 7.26e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  127 INPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMV 206
Cdd:pfam00308   1 LNPRYTFENFVIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEFLNDFV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  207 KALQNNAIEDFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLT 286
Cdd:pfam00308  81 DAIRDNKTNQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGKQIVFSSDRPPKELEELEDRLRSRFQWGLV 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 640581526  287 VAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFT 345
Cdd:pfam00308 161 TDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVRELEGALNRLLAYSSLN 219
Bac_DnaA_C cd06571
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA ...
371-460 1.43e-41

C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple copies of DnaA, which is an ATPase, bind to 9-mers at the origin and form an initial complex in which the DNA strands are being separated in an ATP-dependent step.


Pssm-ID: 119330 [Multi-domain]  Cd Length: 90  Bit Score: 142.65  E-value: 1.43e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 371 IDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQMAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIK 450
Cdd:cd06571    1 IELIIEAVAEYFGISVEDLRSKSRKKEIALARQIAMYLARELTGLSLPEIGRAFGGRDHSTVLHAVRKIEELLEEDPELK 80
                         90
                 ....*....|
gi 640581526 451 EDYANLIRTL 460
Cdd:cd06571   81 EDVEELEKKL 90
Bac_DnaA_C smart00760
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.
370-438 2.13e-36

Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.


Pssm-ID: 197863 [Multi-domain]  Cd Length: 69  Bit Score: 128.39  E-value: 2.13e-36
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 640581526   370 TIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQMAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRK 438
Cdd:smart00760   1 TIEEIIEAVAEYFGVKPEDLKSKSRKREIVLARQIAMYLARELTDLSLPEIGKIFGGRDHSTVLHACRK 69
 
Name Accession Description Interval E-value
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
6-460 0e+00

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 717.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526    6 WQQCIGRLQDELSAQQFSMWIRPLQA-EMDGDTLVIYAPNRFVLDWVRDKYLNIINQFFTEHLGNDaPKLRFDIGSRPSA 84
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLlSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAE-IEIEFTVGEDEEE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526   85 -KPQVQTPTATKASVSAPKSAagkgatfntaaepavnhsyRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPL 163
Cdd:TIGR00362  80 lEPNSKKPEPAPPEAPAPPSS-------------------ASGLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPL 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  164 FLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEDFKRYYRSVDALFIDDIQFFANKDRSQE 243
Cdd:TIGR00362 141 FIYGGVGLGKTHLLHAIGNEILENNPNAKVLYVSSEKFTNDFVNALRNNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQE 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  244 EFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKR 323
Cdd:TIGR00362 221 EFFHTFNALHENNKQIVLTSDRPPKELPGLEDRLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKN 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  324 LRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQ 403
Cdd:TIGR00362 301 ITSNVRELEGALNRLLAYASLTGKPITLELAKEALKDLLRAQKKEITIENIQKVVAKYYNIKVSDLKSKKRTRNIVRPRQ 380
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 640581526  404 MAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTL 460
Cdd:TIGR00362 381 IAMYLAKELTDLSLPEIGKAFGGRDHTTVLHAVRKIEKLIETDAELKEDIEELKRKL 437
dnaA PRK00149
chromosomal replication initiator protein DnaA;
1-462 0e+00

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 709.98  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526   1 MAVSLWQQCIGRLQDELSAQQFSMWIRPLQ-AEMDGDTLVIYAPNRFVLDWVRDKYLNIINQFFTehlgndapklrfdig 79
Cdd:PRK00149   1 NLQSLWEKVLERLKDELSEQEYETWIKPLKaLSLEDNTLTLYVPNRFVKDWIEKNYLDLIEEALQ--------------- 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  80 srpsakpqvqtptatkasvsapksaagkgatfntaaepavnhsyrsnINPTYQFDNFVEGKSNQLGKAAALQVAENPGGA 159
Cdd:PRK00149  66 -----------------------------------------------LNPKYTFDNFVVGKSNRLAHAAALAVAENPGKA 98
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 160 YNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEDFKRYYRSVDALFIDDIQFFANKD 239
Cdd:PRK00149  99 YNPLFIYGGVGLGKTHLLHAIGNYILEKNPNAKVVYVTSEKFTNDFVNALRNNTMEEFKEKYRSVDVLLIDDIQFLAGKE 178
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 240 RSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFF 319
Cdd:PRK00149 179 RTQEEFFHTFNALHEAGKQIVLTSDRPPKELPGLEERLRSRFEWGLTVDIEPPDLETRIAILKKKAEEEGIDLPDEVLEF 258
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 320 IAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVA 399
Cdd:PRK00149 259 IAKNITSNVRELEGALNRLIAYASLTGKPITLELAKEALKDLLAAQKKKITIENIQKVVAEYYNIKVSDLKSKSRTRNIA 338
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 640581526 400 RPRQMAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS 462
Cdd:PRK00149 339 RPRQIAMYLAKELTDLSLPEIGRAFGGRDHTTVLHAVRKIEKLLEEDPELKEDVEELKRKLKS 401
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
127-429 0e+00

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 548.64  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 127 INPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMV 206
Cdd:COG0593    1 LNPRYTFDNFVVGPSNRLAHAAALAVAEWPGKAYNPLFLYGGVGLGKTHLLHAIGNEALENNPGARVVYLTAEEFTNDFI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 207 KALQNNAIEDFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLT 286
Cdd:COG0593   81 NAIRNNTIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWGLV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 287 VAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQE 366
Cdd:COG0593  161 VDIQPPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLKDLLRAQK 240
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 640581526 367 KLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQMAMALSKELTNQSLPEIGDAFGGRDH 429
Cdd:COG0593  241 KEITIEDIQKAVAEYFGVSVADLLSKSRTREIARPRQIAMYLARELTDLSLPEIGRAFGGRDH 303
Bac_DnaA pfam00308
Bacterial dnaA protein;
127-345 7.26e-127

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 367.04  E-value: 7.26e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  127 INPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMV 206
Cdd:pfam00308   1 LNPRYTFENFVIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEFLNDFV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  207 KALQNNAIEDFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLT 286
Cdd:pfam00308  81 DAIRDNKTNQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGKQIVFSSDRPPKELEELEDRLRSRFQWGLV 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 640581526  287 VAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFT 345
Cdd:pfam00308 161 TDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVRELEGALNRLLAYSSLN 219
dnaA PRK14086
chromosomal replication initiator protein DnaA;
86-449 1.68e-121

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 367.61  E-value: 1.68e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  86 PQVQTPTATKASVSAPKSAAGKGATFNTAAEPAvnhsyrSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPLFL 165
Cdd:PRK14086 246 PERDDAPVVPIRPSAPGPLAAQPAPAPGPGEPT------ARLNPKYTFDTFVIGASNRFAHAAAVAVAEAPAKAYNPLFI 319
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 166 YGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEDFKRYYRSVDALFIDDIQFFANKDRSQEEF 245
Cdd:PRK14086 320 YGESGLGKTHLLHAIGHYARRLYPGTRVRYVSSEEFTNEFINSIRDGKGDSFRRRYREMDILLVDDIQFLEDKESTQEEF 399
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 246 FHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLR 325
Cdd:PRK14086 400 FHTFNTLHNANKQIVLSSDRPPKQLVTLEDRLRNRFEWGLITDVQPPELETRIAILRKKAVQEQLNAPPEVLEFIASRIS 479
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 326 SNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKL-VTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQM 404
Cdd:PRK14086 480 RNIRELEGALIRVTAFASLNRQPVDLGLTEIVLRDLIPEDSAPeITAAAIMAATADYFGLTVEDLCGTSRSRVLVTARQI 559
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 640581526 405 AMALSKELTNQSLPEIGDAFgGRDHTTVLHACRKIAQLREESHDI 449
Cdd:PRK14086 560 AMYLCRELTDLSLPKIGQQF-GRDHTTVMHADRKIRALMAERRSI 603
PRK12422 PRK12422
chromosomal replication initiator protein DnaA;
6-462 1.34e-76

chromosomal replication initiator protein DnaA;


Pssm-ID: 183521 [Multi-domain]  Cd Length: 445  Bit Score: 246.29  E-value: 1.34e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526   6 WQQCIGRLQDELSAQQFSMWIRPLQ-AEMDGDTLVIYAPNRFVLDWVRDKYLNIINQFFtehLGNDAPKLRFDIGSRPSA 84
Cdd:PRK12422   4 WEEFLLLQEKEIGTETVDKWLRSLKvLCFDACNLYLEAKDSFQVTWFEEHIRHKVKASL---VNNNGKPIRVHVTSLDKS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  85 KPQVQTPTATKAsvsapksaagKGATFNTAAEpavnhsyrsNINPTYQFDNFVEGKSNQLGKAAALQVA----ENPGGAY 160
Cdd:PRK12422  81 TPFKKEKQIQQE----------KTAYFTMKYG---------ELDPLMTFANFLVTPENDLPHRILQEFTkvseQGKGFPF 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 161 NPLFLYGGTGLGKTHLLHAVGNGIikNNPNAKVVYMHSERFVQDMVKALQNNAIEDFKRYYRSVDALFIDDIQFFANKDR 240
Cdd:PRK12422 142 NPIYLFGPEGSGKTHLMQAAVHAL--RESGGKILYVRSELFTEHLVSAIRSGEMQRFRQFYRNVDALFIEDIEVFSGKGA 219
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 241 SQEEFFHTFNAL-LEGNhQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFF 319
Cdd:PRK12422 220 TQEEFFHTFNSLhTEGK-LIVISSTCAPQDLKAMEERLISRFEWGIAIPLHPLTKEGLRSFLERKAEALSIRIEETALDF 298
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 320 IAKRLRSNVRELEGALNRV---IANANFTGRPITIDFVREALRDLLALQEKL-VTIDNIQKTVAEYYKIKMADMLSKRRS 395
Cdd:PRK12422 299 LIEALSSNVKSLLHALTLLakrVAYKKLSHQLLYVDDIKALLHDVLEAAESVrLTPSKIIRAVAQYYGVSPESILGRSQS 378
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 640581526 396 RSVARPRQMAMALSKELTNQSLPEIGDAFgGRDHTTVLHACRKIAQ-LREESHDIKEDYANLIRTLSS 462
Cdd:PRK12422 379 REYVLPRQVAMYLCRQKLSLSYVKIGDVF-SRDHSTVISSIRAISQkLEEDDRDISMAIQEITKRLSS 445
Bac_DnaA_C cd06571
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA ...
371-460 1.43e-41

C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple copies of DnaA, which is an ATPase, bind to 9-mers at the origin and form an initial complex in which the DNA strands are being separated in an ATP-dependent step.


Pssm-ID: 119330 [Multi-domain]  Cd Length: 90  Bit Score: 142.65  E-value: 1.43e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 371 IDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQMAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIK 450
Cdd:cd06571    1 IELIIEAVAEYFGISVEDLRSKSRKKEIALARQIAMYLARELTGLSLPEIGRAFGGRDHSTVLHAVRKIEELLEEDPELK 80
                         90
                 ....*....|
gi 640581526 451 EDYANLIRTL 460
Cdd:cd06571   81 EDVEELEKKL 90
Bac_DnaA_C pfam08299
Bacterial dnaA protein helix-turn-helix;
371-439 8.14e-39

Bacterial dnaA protein helix-turn-helix;


Pssm-ID: 462419 [Multi-domain]  Cd Length: 69  Bit Score: 134.84  E-value: 8.14e-39
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 640581526  371 IDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQMAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKI 439
Cdd:pfam08299   1 IEKIIEAVAEYFGISPEDLKSKSRKREIALARQIAMYLARELTDLSLPEIGRAFGGRDHSTVIHACKKI 69
Bac_DnaA_C smart00760
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.
370-438 2.13e-36

Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.


Pssm-ID: 197863 [Multi-domain]  Cd Length: 69  Bit Score: 128.39  E-value: 2.13e-36
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 640581526   370 TIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQMAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRK 438
Cdd:smart00760   1 TIEEIIEAVAEYFGVKPEDLKSKSRKREIVLARQIAMYLARELTDLSLPEIGKIFGGRDHSTVLHACRK 69
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
133-359 2.39e-35

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 130.77  E-value: 2.39e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  133 FDNFVEGkSNQLGKAAALQVAENPGGayNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAkvVYMHSERFVQDMVKALqnN 212
Cdd:TIGR03420  14 FDNFYAG-GNAELLAALRQLAAGKGD--RFLYLWGESGSGKSHLLQAACAAAEERGKSA--IYLPLAELAQADPEVL--E 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526  213 AIEDFkryyrsvDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPP 292
Cdd:TIGR03420  87 GLEQA-------DLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGRLLIAGRAAPAQLPLRLPDLRTRLAWGLVFQLPPL 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 640581526  293 ELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALR 359
Cdd:TIGR03420 160 SDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
DnaA_N pfam11638
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a ...
4-65 2.30e-20

DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a protein involved in the initiation of bacterial chromosomal replication. The structure of this domain is known. It is also found in three copies in some proteins. The exact function of this domain is uncertain but it has been suggested to play a role in oligomerization.


Pssm-ID: 463316 [Multi-domain]  Cd Length: 65  Bit Score: 84.64  E-value: 2.30e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 640581526    4 SLWQQCIGRLQDELSAQQFSMWIRPLQAEM--DGDTLVIYAPNRFVLDWVRDKYLNIINQFFTE 65
Cdd:pfam11638   2 ELWERVLERLRKEVGEQTFNTWIKPLTLVDldDGGSLTLSVPNRFVRDWVEEHYLDRILELWQE 65
PRK08084 PRK08084
DnaA inactivator Hda;
133-359 4.02e-20

DnaA inactivator Hda;


Pssm-ID: 181224 [Multi-domain]  Cd Length: 235  Bit Score: 88.97  E-value: 4.02e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 133 FDNFVEGKSNQLgkAAALQ-VAENPGGAYnpLFLYGGTGLGKTHLLHAVGNGIikNNPNAKVVYMHSER---FVQDMVKA 208
Cdd:PRK08084  21 FASFYPGDNDSL--LAALQnALRQEHSGY--IYLWSREGAGRSHLLHAACAEL--SQRGRAVGYVPLDKrawFVPEVLEG 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 209 LQnnaiedfkryyrSVDALFIDDIQFFANKDRSQEEFFHTFNALLE-GNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTV 287
Cdd:PRK08084  95 ME------------QLSLVCIDNIECIAGDELWEMAIFDLYNRILEsGRTRLLITGDRPPRQLNLGLPDLASRLDWGQIY 162
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 640581526 288 AIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALR 359
Cdd:PRK08084 163 KLQPLSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILK 234
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
142-285 6.54e-19

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 83.35  E-value: 6.54e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 142 NQLGKAAALQVAENPggAYNPLFLYGGTGLGKTHLLHAVGNGIIKnnPNAKVVYMHSERFVQDMVKALQ----NNAIEDF 217
Cdd:cd00009    3 QEEAIEALREALELP--PPKNLLLYGPPGTGKTTLARAIANELFR--PGAPFLYLNASDLLEGLVVAELfghfLVRLLFE 78
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 640581526 218 KRYYRSVDALFIDDIQFFANKDRSQ-EEFFHTFNALLE--GNHQIILTSDR--YPKEIDGVEDRLKSRFGWGL 285
Cdd:cd00009   79 LAEKAKPGVLFIDEIDSLSRGAQNAlLRVLETLNDLRIdrENVRVIGATNRplLGDLDRALYDRLDIRIVIPL 151
PRK08903 PRK08903
DnaA regulatory inactivator Hda; Validated
129-358 6.36e-18

DnaA regulatory inactivator Hda; Validated


Pssm-ID: 236347 [Multi-domain]  Cd Length: 227  Bit Score: 82.33  E-value: 6.36e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 129 PTyqFDNFVEGKSNQLGKAAALQVAENPGGAYnpLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSerfvqdmvka 208
Cdd:PRK08903  15 PT--FDNFVAGENAELVARLRELAAGPVADRF--FYLWGEAGSGRSHLLQALVADASYGGRNARYLDAAS---------- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 209 lqnnAIEDFKrYYRSVDALFIDDIQFFANKDrsQEEFFHTFNALLEGNHQIILTS-DRYPKEIDGVEDrLKSRFGWGLTV 287
Cdd:PRK08903  81 ----PLLAFD-FDPEAELYAVDDVERLDDAQ--QIALFNLFNRVRAHGQGALLVAgPAAPLALPLRED-LRTRLGWGLVY 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 640581526 288 AIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREAL 358
Cdd:PRK08903 153 ELKPLSDADKIAALKAAAAERGLQLADEVPDYLLTHFRRDMPSLMALLDALDRYSLEQKRPVTLPLLREML 223
PRK06030 PRK06030
hypothetical protein; Provisional
378-445 2.39e-10

hypothetical protein; Provisional


Pssm-ID: 180356  Cd Length: 124  Bit Score: 57.86  E-value: 2.39e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 640581526 378 VAEYYKIKMADMLS-KRRSRSVARPRQMAMALSKELTNQSLPEIGDAFGgRDHTTVLHACRKIAQLREE 445
Cdd:PRK06030  32 LALAFGVSGAEIASpLRGRREVSRIRQIAMYVAHVSLGWPMNEVALAFG-RDRTTVGHACHTVEDLRDD 99
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
163-263 4.76e-10

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 59.79  E-value: 4.76e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 163 LFLYGGTGLGKTHLLHAVGNGIIKNNPnaKVVYMHSERFVQDMVKALQNNAIEDFKRYYRSVDALFIDDIqFFANKDRSQ 242
Cdd:COG1484  102 LILLGPPGTGKTHLAIALGHEACRAGY--RVRFTTAPDLVNELKEARADGRLERLLKRLAKVDLLILDEL-GYLPLDAEG 178
                         90       100
                 ....*....|....*....|..
gi 640581526 243 -EEFFHTFNALLEgNHQIILTS 263
Cdd:COG1484  179 aELLFELISDRYE-RRSTIITS 199
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
161-280 1.90e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 50.45  E-value: 1.90e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526   161 NPLFLYGGTGLGKTHLLHAVGNGIIKnnPNAKVVYMHSERFVQDMVKALQNNAIEDFKRY---------------YRSVD 225
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGP--PGGGVIYIDGEDILEEVLDQLLLIIVGGKKASgsgelrlrlalalarKLKPD 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526   226 ALFIDDIQFFANKDRSQEEFFHTFNALL-----EGNHQIILTSDRYPKEIDGVEDRLKSR 280
Cdd:smart00382  81 VLILDEITSLLDAEQEALLLLLEELRLLlllksEKNLTVILTTNDEKDLGPALLRRRFDR 140
PRK06672 PRK06672
hypothetical protein; Validated
4-84 3.17e-07

hypothetical protein; Validated


Pssm-ID: 180654 [Multi-domain]  Cd Length: 341  Bit Score: 52.07  E-value: 3.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526   4 SLWQQCIGRLQDELSAQQFSMWIRPLQAEMDGDTLVIYAPNRFVLDWVRDKYLNIINQFFTEHLGNDApKLRFDIGSRPS 83
Cdd:PRK06672 193 TIWNKIKDKMQLKISRPSYETWVKETTARINEDSLIIYFENEFQQEWVKKSYKDLISQIAKELTGNTY-EIQFELKSNTT 271

                 .
gi 640581526  84 A 84
Cdd:PRK06672 272 S 272
PRK06835 PRK06835
DNA replication protein DnaC; Validated
163-281 1.20e-06

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 50.28  E-value: 1.20e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 163 LFLYGGTGLGKTHLLHAVGNGIIKnnpNAK-VVYMHSERFVQDMVKALQNNAIEDFKRY--YRSVDALFIDDIQFFANKD 239
Cdd:PRK06835 186 LLFYGNTGTGKTFLSNCIAKELLD---RGKsVIYRTADELIEILREIRFNNDKELEEVYdlLINCDLLIIDDLGTEKITE 262
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 640581526 240 RSQEEFFHTFNA-LLEGNHQIILT-------SDRYPKEIdgvEDRLKSRF 281
Cdd:PRK06835 263 FSKSELFNLINKrLLRQKKMIISTnlsleelLKTYSERI---SSRLLGNF 309
PRK08939 PRK08939
primosomal protein DnaI; Reviewed
163-232 2.07e-05

primosomal protein DnaI; Reviewed


Pssm-ID: 236353 [Multi-domain]  Cd Length: 306  Bit Score: 46.40  E-value: 2.07e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 163 LFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSerFVQDMVKALQNNAIEDFKRYYRSVDALFIDDI 232
Cdd:PRK08939 159 LYLYGDFGVGKSYLLAAIANELAKKGVSSTLLHFPE--FIRELKNSISDGSVKEKIDAVKEAPVLMLDDI 226
PRK06672 PRK06672
hypothetical protein; Validated
3-89 1.23e-04

hypothetical protein; Validated


Pssm-ID: 180654 [Multi-domain]  Cd Length: 341  Bit Score: 43.98  E-value: 1.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526   3 VSLWQQCIGRLQDELSAQQFSMWIRPLQAEMDGDTLVIYAPNRFVLDWVRDKYLNIINQfFTEHLGNDAPKLRFDIGSRP 82
Cdd:PRK06672  92 LSSWDEVKKALRPKIAEKTFMTWIRNTNATIKDNKVIIFCEDAFHRDLLEGEYKNIISS-TVQKITDEEYQIWFEIGSSA 170

                 ....*..
gi 640581526  83 SAKPQVQ 89
Cdd:PRK06672 171 TSKAQVH 177
PRK06921 PRK06921
hypothetical protein; Provisional
125-289 1.60e-04

hypothetical protein; Provisional


Pssm-ID: 180750 [Multi-domain]  Cd Length: 266  Bit Score: 43.23  E-value: 1.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 125 SNINPTYQ---FDNFV-EGKSnQLGKAA---ALQVAEN----PGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKV 193
Cdd:PRK06921  72 SEITEAFRkltFKNFKtEGKP-QAIKDAyecAVEYVKDfekiQESRKNSIALLGQPGSGKTHLLTAAANELMRKKGVPVL 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 194 VYMHSERFvqDMVKALQNNAIEDFKRyYRSVDALFIDDIQFFANKDRSQEEF-FHTFNALLEG---NHQ-IILTSDRYPK 268
Cdd:PRK06921 151 YFPFVEGF--GDLKDDFDLLEAKLNR-MKKVEVLFIDDLFKPVNGKPRATEWqIEQMYSVLNYrylNHKpILISSELTID 227
                        170       180
                 ....*....|....*....|....
gi 640581526 269 EIDGVEDRLKSRF---GWGLTVAI 289
Cdd:PRK06921 228 ELLDIDEALGSRIvemCKDYLVII 251
PRK07952 PRK07952
DNA replication protein DnaC; Validated
124-232 3.49e-04

DNA replication protein DnaC; Validated


Pssm-ID: 181180 [Multi-domain]  Cd Length: 244  Bit Score: 42.06  E-value: 3.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 124 RSNINPTYQ---FDNF-VEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYmhse 199
Cdd:PRK07952  59 RSGIRPLHQncsFENYrVECEGQMNALSKARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIIT---- 134
                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 640581526 200 rfVQDMVKALQ------NNAIEDFKRYYRSVDALFIDDI 232
Cdd:PRK07952 135 --VADIMSAMKdtfsnsETSEEQLLNDLSNVDLLVIDEI 171
PRK06620 PRK06620
hypothetical protein; Validated
121-358 3.77e-04

hypothetical protein; Validated


Pssm-ID: 168630  Cd Length: 214  Bit Score: 41.75  E-value: 3.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 121 HSYRSNINPTYQFDNFVEGKSNqlgkAAALQVAENPGGAY--NP----LFLYGGTGLGKTHLLHavgngIIKNNPNAkvv 194
Cdd:PRK06620   3 YIFRFTTSSKYHPDEFIVSSSN----DQAYNIIKNWQCGFgvNPykftLLIKGPSSSGKTYLTK-----IWQNLSNA--- 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 195 YMHSERFVQDmvkalqnnaiedfkRYYRSVDALFIDDIQFFANKdrsqeEFFHTFNALLEGNHQIILTSDRYPKEIdgVE 274
Cdd:PRK06620  71 YIIKDIFFNE--------------EILEKYNAFIIEDIENWQEP-----ALLHIFNIINEKQKYLLLTSSDKSRNF--TL 129
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 275 DRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFV 354
Cdd:PRK06620 130 PDLSSRIKSVLSILLNSPDDELIKILIFKHFSISSVTISRQIIDFLLVNLPREYSKIIEILENINYFALISKRKITISLV 209

                 ....
gi 640581526 355 REAL 358
Cdd:PRK06620 210 KEVL 213
CDC6 COG1474
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
128-369 6.76e-04

Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];


Pssm-ID: 441083 [Multi-domain]  Cd Length: 389  Bit Score: 41.76  E-value: 6.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 128 NPTYQFDNFV--EGKSNQLgkAAALQVAENpGGAYNPLFLYGGTGLGKTHLLHAVGNGI----IKNNPNAKVVY-----M 196
Cdd:COG1474   20 SPDYVPDRLPhrEEEIEEL--ASALRPALR-GERPSNVLIYGPTGTGKTAVAKYVLEELeeeaEERGVDVRVVYvncrqA 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 197 HSE-RFVQDMVKALQNN---------AIEDFKRYYRSVDALF------IDDIQFFANKDRSQE-EFFHTFNALLEGNH-Q 258
Cdd:COG1474   97 STRyRVLSRILEELGSGedipstglsTDELFDRLYEALDERDgvlvvvLDEIDYLVDDEGDDLlYQLLRANEELEGARvG 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 259 IILTSdRYPKEIDGVEDRLKSRFGwGLTVAIEP---PELetrVAILMRKAQEsGIN---LPDEVAFFIAK---RLRSNVR 329
Cdd:COG1474  177 VIGIS-NDLEFLENLDPRVKSSLG-EEEIVFPPydaDEL---RDILEDRAEL-AFYdgvLSDEVIPLIAAlaaQEHGDAR 250
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 640581526 330 ElegALN--RV---IANANftGRP-ITIDFVREALRDL-----------LALQEKLV 369
Cdd:COG1474  251 K---AIDllRVageIAERE--GSDrVTEEHVREAREKIerdrllevlrgLPTHEKLV 302
PRK06672 PRK06672
hypothetical protein; Validated
6-89 8.47e-04

hypothetical protein; Validated


Pssm-ID: 180654 [Multi-domain]  Cd Length: 341  Bit Score: 41.29  E-value: 8.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526   6 WQQCIGRLQDELSAQQFSMWIRPLQAEMDGDTLVIYAPNRFVLDWVRDKYLNIINQFFTEhLGNDAPKLRFDI-GSRPSA 84
Cdd:PRK06672   5 WTEVKEKIRPQISKPSYETWFTNTTVYLEDDILTIYCPNEFARDWLESHYKELVFNTLRE-MFNTTFEIQFDLcNGEPSN 83

                 ....*
gi 640581526  85 KPQVQ 89
Cdd:PRK06672  84 LKDVQ 88
PRK08116 PRK08116
hypothetical protein; Validated
131-232 2.06e-03

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 40.00  E-value: 2.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 131 YQFDNF-VEGKSNQLGKAAALQV-------AENPGgaynpLFLYGGTGLGKTHLLHAVGNGIIKNnpNAKVVYMHSERFV 202
Cdd:PRK08116  82 STFENFlFDKGSEKAYKIARKYVkkfeemkKENVG-----LLLWGSVGTGKTYLAACIANELIEK--GVPVIFVNFPQLL 154
                         90       100       110
                 ....*....|....*....|....*....|...
gi 640581526 203 QDMVKALQNNAIEDFKRYYRSV---DALFIDDI 232
Cdd:PRK08116 155 NRIKSTYKSSGKEDENEIIRSLvnaDLLILDDL 187
PRK12377 PRK12377
putative replication protein; Provisional
124-232 9.31e-03

putative replication protein; Provisional


Pssm-ID: 183482 [Multi-domain]  Cd Length: 248  Bit Score: 37.89  E-value: 9.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640581526 124 RSNINPTYQ---FDNF-VEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYmhse 199
Cdd:PRK12377  61 RSGIQPLHRkcsFANYqVQNDGQRYALSQAKSIADELMTGCTNFVFSGKPGTGKNHLAAAIGNRLLAKGRSVIVVT---- 136
                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 640581526 200 rfVQDMVKALQN-----NAIEDFKRYYRSVDALFIDDI 232
Cdd:PRK12377 137 --VPDVMSRLHEsydngQSGEKFLQELCKVDLLVLDEI 172
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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