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Conserved domains on  [gi|640682786|ref|WP_025107265|]
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MULTISPECIES: GNAT family N-acetyltransferase [Klebsiella]

Protein Classification

GNAT family protein( domain architecture ID 106742)

GNAT (Gcn5-related N-acetyltransferase) family protein similar to N-acetyltransferases that catalyze the transfer of an acetyl group from acetyl-CoA to a substrate

PubMed:  15581578

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NAT_SF super family cl17182
N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of ...
 2-147 1.30e-66

N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase which catalyze the transfer of an acetyl group to a substrate. The mechanism is an ordered Bi-Bi ternary complex kinetic mechanism for most GNATs: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and then CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/ph enylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


The actual alignment was detected with superfamily member PRK09831:

Pssm-ID: 473072  Cd Length: 147  Bit Score: 199.03  E-value: 1.30e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   2 LTIRMYEERDFPALCALFLRAVKETASADYSPRQIAAWAQVDEARWRQKLAASRVLVAINDASPVGFITAVDDYIDLLFV 81
Cdd:PRK09831   1 IQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQIAAWAQIDESRWKEKLAKSQVRVAVINAQPVGFITCIEHYIDMLFV 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 640682786  82 SPDYSRQGVASALLNTLLRQLPErvYTVEASITAKPFFARHGFTVMQPQEVTARGEQFLNYLMRRQ 147
Cdd:PRK09831  81 DPEYTRRGVASALLKPLIKSESE--LTVDASITAKPFFERYGFQTVKQQRVECRGEWFINFYMRYK 144
 
Name Accession Description Interval E-value
PRK09831 PRK09831
GNAT family N-acetyltransferase;
2-147 1.30e-66

GNAT family N-acetyltransferase;


Pssm-ID: 182099  Cd Length: 147  Bit Score: 199.03  E-value: 1.30e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   2 LTIRMYEERDFPALCALFLRAVKETASADYSPRQIAAWAQVDEARWRQKLAASRVLVAINDASPVGFITAVDDYIDLLFV 81
Cdd:PRK09831   1 IQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQIAAWAQIDESRWKEKLAKSQVRVAVINAQPVGFITCIEHYIDMLFV 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 640682786  82 SPDYSRQGVASALLNTLLRQLPErvYTVEASITAKPFFARHGFTVMQPQEVTARGEQFLNYLMRRQ 147
Cdd:PRK09831  81 DPEYTRRGVASALLKPLIKSESE--LTVDASITAKPFFERYGFQTVKQQRVECRGEWFINFYMRYK 144
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 29-132 1.22e-17

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 73.84  E-value: 1.22e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   29 ADYSPRQIAAWA-QVDEARWRQKLAASR--VLVAINDASPVGFITAVDD-YIDLLFVSPDYSRQGVASALLNTLLRQLPE 104
Cdd:pfam13673   3 PDYSEEGIETFYeFISPEALRERIDQGEyfFFVAFEGGQIVGVIALRDRgHISLLFVDPDYQGQGIGKALLEAVEDYAEK 82

                          90       100       110
                  ....*....|....*....|....*....|...
gi 640682786  105 RVY-----TVEASITAKPFFARHGFTVMQPQEV 132
Cdd:pfam13673  83 DGIklselTVNASPYAVPFYEKLGFRATGPEQE 115
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-148 1.75e-17

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 74.26  E-value: 1.75e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   1 MLTIRMYEERDFPALCALFLRAVKE-TASADYSPRQIAAWaqvdEARWRQKLAASR-VLVAINDASPVGFITAVDD---- 74
Cdd:COG1247    1 EMTIRPATPEDAPAIAAIYNEAIAEgTATFETEPPSEEER----EAWFAAILAPGRpVLVAEEDGEVVGFASLGPFrprp 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786  75 -----YIDLLFVSPDYSRQGVASALLNTLLRQLPER-VYTVEASIT-----AKPFFARHGFTVMQPQEVTAR--GEQFLN 141
Cdd:COG1247   77 ayrgtAEESIYVDPDARGRGIGRALLEALIERARARgYRRLVAVVLadneaSIALYEKLGFEEVGTLPEVGFkfGRWLDL 156


                 ....*..
gi 640682786 142 YLMRRQI 148
Cdd:COG1247  157 VLMQKRL 163
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 56-105 1.86e-08

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 48.43  E-value: 1.86e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 640682786  56 VLVAINDASPVGFITAVDD-------YIDLLFVSPDYSRQGVASALLNTLLRQLPER 105
Cdd:cd04301    1 FLVAEDDGEIVGFASLSPDgsggdtaYIGDLAVLPEYRGKGIGSALLEAAEEEARER 57
 
Name Accession Description Interval E-value
PRK09831 PRK09831
GNAT family N-acetyltransferase;
2-147 1.30e-66

GNAT family N-acetyltransferase;


Pssm-ID: 182099  Cd Length: 147  Bit Score: 199.03  E-value: 1.30e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   2 LTIRMYEERDFPALCALFLRAVKETASADYSPRQIAAWAQVDEARWRQKLAASRVLVAINDASPVGFITAVDDYIDLLFV 81
Cdd:PRK09831   1 IQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQIAAWAQIDESRWKEKLAKSQVRVAVINAQPVGFITCIEHYIDMLFV 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 640682786  82 SPDYSRQGVASALLNTLLRQLPErvYTVEASITAKPFFARHGFTVMQPQEVTARGEQFLNYLMRRQ 147
Cdd:PRK09831  81 DPEYTRRGVASALLKPLIKSESE--LTVDASITAKPFFERYGFQTVKQQRVECRGEWFINFYMRYK 144
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 29-132 1.22e-17

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 73.84  E-value: 1.22e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   29 ADYSPRQIAAWA-QVDEARWRQKLAASR--VLVAINDASPVGFITAVDD-YIDLLFVSPDYSRQGVASALLNTLLRQLPE 104
Cdd:pfam13673   3 PDYSEEGIETFYeFISPEALRERIDQGEyfFFVAFEGGQIVGVIALRDRgHISLLFVDPDYQGQGIGKALLEAVEDYAEK 82

                          90       100       110
                  ....*....|....*....|....*....|...
gi 640682786  105 RVY-----TVEASITAKPFFARHGFTVMQPQEV 132
Cdd:pfam13673  83 DGIklselTVNASPYAVPFYEKLGFRATGPEQE 115
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-148 1.75e-17

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 74.26  E-value: 1.75e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   1 MLTIRMYEERDFPALCALFLRAVKE-TASADYSPRQIAAWaqvdEARWRQKLAASR-VLVAINDASPVGFITAVDD---- 74
Cdd:COG1247    1 EMTIRPATPEDAPAIAAIYNEAIAEgTATFETEPPSEEER----EAWFAAILAPGRpVLVAEEDGEVVGFASLGPFrprp 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786  75 -----YIDLLFVSPDYSRQGVASALLNTLLRQLPER-VYTVEASIT-----AKPFFARHGFTVMQPQEVTAR--GEQFLN 141
Cdd:COG1247   77 ayrgtAEESIYVDPDARGRGIGRALLEALIERARARgYRRLVAVVLadneaSIALYEKLGFEEVGTLPEVGFkfGRWLDL 156


                 ....*..
gi 640682786 142 YLMRRQI 148
Cdd:COG1247  157 VLMQKRL 163
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
4-140 1.71e-14

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 66.26  E-value: 1.71e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   4 IRMYEERDFPALCALFLRAvketasadYSPRQIAAWAqvdeARWRQKLAASRVLVAINDASPVGFITAVDD--------- 74
Cdd:COG3153    1 IRPATPEDAEAIAALLRAA--------FGPGREAELV----DRLREDPAAGLSLVAEDDGEIVGHVALSPVdidgegpal 68

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 640682786  75 YIDLLFVSPDYSRQGVASALLNTLLRQLPERVYT---VEASITAKPFFARHGFTVMQPQEVTARGEQFL 140
Cdd:COG3153   69 LLGPLAVDPEYRGQGIGRALMRAALEAARERGARavvLLGDPSLLPFYERFGFRPAGELGLTLGPDEVF 137
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 54-126 9.97e-12

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 57.46  E-value: 9.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   54 SRVLVAINDASPVGFITAVDD------YIDLLFVSPDYSRQGVASALLNTL---LRQLPERVYTVEASITAKPFFARHGF 124
Cdd:pfam13508   3 GRFFVAEDDGKIVGFAALLPLddegalAELRLAVHPEYRGQGIGRALLEAAeaaAKEGGIKLLELETTNRAAAFYEKLGF 82


                  ..
gi 640682786  125 TV 126
Cdd:pfam13508  83 EE 84
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 2-149 1.51e-11

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 58.08  E-value: 1.51e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   2 LTIRMYEERDFPALCALflravketasadysprqIAAWAQVDEARwrqklaasRVLVAINDASPVGFITAVDD-----YI 76
Cdd:COG1246    1 MTIRPATPDDVPAILEL-----------------IRPYALEEEIG--------EFWVAEEDGEIVGCAALHPLdedlaEL 55

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 640682786  77 DLLFVSPDYSRQGVASALLNTLLRQL----PERVYtVEASITAKPFFARHGFTVMQPQEV-TARGEQFLNYLMRRQID 149
Cdd:COG1246   56 RSLAVHPDYRGRGIGRRLLEALLAEArelgLKRLF-LLTTSAAIHFYEKLGFEEIDKEDLpYAKVWQRDSVVMEKDLE 132
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 42-124 4.49e-10

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 54.06  E-value: 4.49e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   42 VDEARWRQKLAASRVLVAINDASPVGFITAVDD-------YIDLLFVSPDYSRQGVASALLNTLLRQLPER------VYT 108
Cdd:pfam00583  21 LDLLEDWDEDASEGFFVAEEDGELVGFASLSIIddeppvgEIEGLAVAPEYRGKGIGTALLQALLEWARERgcerifLEV 100

                          90
                  ....*....|....*.
gi 640682786  109 VEASITAKPFFARHGF 124
Cdd:pfam00583 101 AADNLAAIALYEKLGF 116
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 48-137 1.60e-09

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 52.75  E-value: 1.60e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786  48 RQKLAASRVLVAINDA-SPVGFITA--VDD---YIDLLFVSPDYSRQGVASALLNTLLRQLPER------VYTVEASITA 115
Cdd:COG0454   27 MEGSLAGAEFIAVDDKgEPIGFAGLrrLDDkvlELKRLYVLPEYRGKGIGKALLEALLEWARERgctaleLDTLDGNPAA 106

                         90       100
                 ....*....|....*....|..
gi 640682786 116 KPFFARHGFTVMQPQEVTARGE 137
Cdd:COG0454  107 IRFYERLGFKEIERYVAYVGGE 128
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 67-149 2.91e-09

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 51.19  E-value: 2.91e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786  67 GFITAVDD------YIDLLFVSPDYSRQGVASALLNTLLRQLPER------VYTVEASITAKPFFARHGFTVMqpqEVTA 134
Cdd:COG0456    1 GFALLGLVdggdeaEIEDLAVDPEYRGRGIGRALLEAALERARERgarrlrLEVREDNEAAIALYEKLGFEEV---GERP 77

                         90
                 ....*....|....*
gi 640682786 135 RGEQFLNYLMRRQID 149
Cdd:COG0456   78 NYYGDDALVMEKELA 92
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 56-105 1.86e-08

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 48.43  E-value: 1.86e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 640682786  56 VLVAINDASPVGFITAVDD-------YIDLLFVSPDYSRQGVASALLNTLLRQLPER 105
Cdd:cd04301    1 FLVAEDDGEIVGFASLSPDgsggdtaYIGDLAVLPEYRGKGIGSALLEAAEEEARER 57
PRK10562 PRK10562
putative acetyltransferase; Provisional
 4-151 3.06e-08

putative acetyltransferase; Provisional


Pssm-ID: 236715 [Multi-domain]  Cd Length: 145  Bit Score: 49.68  E-value: 3.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   4 IRMYEERDFPALCALFLravketasadysPRQIAAWAQVDEARWRQK--------LAASRVLVAINDASPVGFITAVDD- 74
Cdd:PRK10562   2 IREYQPSDLPAILQLWL------------ESTIWAHPFIKEQYWRESaplvrdvyLPAAQTWVWEEDGKLLGFVSVLEGr 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786  75 YIDLLFVSPDYSRQGVASALLNTLLRQLPE---RVYtvEASITAKPFFARHGFTVMQP--QEVTargeQFLNYLMRRQID 149
Cdd:PRK10562  70 FVGALFVAPKAVRRGIGKALMQHVQQRYPHlslEVY--QKNQRAVNFYHAQGFRIVDSawQEET----QHPTWIMSWQAD 143


                 ..
gi 640682786 150 PT 151
Cdd:PRK10562 144 QT 145
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
57-149 2.25e-06

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 44.40  E-value: 2.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786  57 LVAINDASPVG----FITAVDDY-IDLLFVSPDYSRQGVASALLNTLL---RQLPERVYTVEASITAKPFFARHGFtvmq 128
Cdd:COG2153   37 LLAYDDGELVAtarlLPPGDGEAkIGRVAVLPEYRGQGLGRALMEAAIeeaRERGARRIVLSAQAHAVGFYEKLGF---- 112

                         90       100
                 ....*....|....*....|....*.
gi 640682786 129 pqevTARGEQFL-----NYLMRRQID 149
Cdd:COG2153  113 ----VPVGEEFLeagipHIDMRKPLS 134
PRK10514 PRK10514
putative acetyltransferase; Provisional
 1-137 9.93e-06

putative acetyltransferase; Provisional


Pssm-ID: 182510 [Multi-domain]  Cd Length: 145  Bit Score: 42.68  E-value: 9.93e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   1 MLTIRMYEERDFPALCALFLRAVKET---ASADYSprqiaawAQVDEaRWRQKLAASRVLVAINDAS-PVGFITAVDDYI 76
Cdd:PRK10514   1 MISIRRSRHEEGERLVAIWRRSVDAThdfLSAEDR-------AEIEE-LVRSFLPEAPLWVAVDERDqPVGFMLLSGGHM 72

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 640682786  77 DLLFVSPDYSRQGVASALLNTLLRQLPERVYTV-EASITAKPFFARHGFtvmqpqEVTARGE 137
Cdd:PRK10514  73 EALFVDPDVRGCGVGRMLVEHALSLHPELTTDVnEQNEQAVGFYKKMGF------KVTGRSE 128
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 1-100 3.25e-05

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 41.91  E-value: 3.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   1 MLTIRMYEERDFPALCALFL--RAVKETASADYSPRQIAAWAQVDEARWRQKLAASRVLVAINDASPVGFIT-----AVD 73
Cdd:COG1670    7 RLRLRPLRPEDAEALAELLNdpEVARYLPGPPYSLEEARAWLERLLADWADGGALPFAIEDKEDGELIGVVGlydidRAN 86

                         90       100
                 ....*....|....*....|....*...
gi 640682786  74 DYIDL-LFVSPDYSRQGVASALLNTLLR 100
Cdd:COG1670   87 RSAEIgYWLAPAYWGKGYATEALRALLD 114
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
75-125 1.54e-03

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 35.65  E-value: 1.54e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 640682786  75 YIDLLFVSPDYSRQGVASALLNTLLRQLPER------VYTVEASITAKPFFARHGFT 125
Cdd:COG3393   17 EISGVYTHPEYRGRGLASALVAALAREALARgartpfLYVDADNPAARRLYERLGFR 73
Eis COG4552
Predicted acetyltransferase [General function prediction only];
2-105 2.32e-03

Predicted acetyltransferase [General function prediction only];


Pssm-ID: 443616 [Multi-domain]  Cd Length: 393  Bit Score: 37.19  E-value: 2.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786   2 LTIRMYEERDFPALCALFLRAVKETASADysprqiaawaqvDEARWRQKLAASRVLVAINDAS----------------- 64
Cdd:COG4552    1 MEIRPLTEDDLDAFARLLAYAFGPEPDDE------------ELEAYRPLLEPGRVLGVFDDGElvgtlalypftlnvgga 68

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 640682786  65 --PVGFITAVDdyidllfVSPDYSRQGVASALLNTLLRQLPER 105
Cdd:COG4552   69 rvPMAGITGVA-------VAPEHRRRGVARALLREALAELRER 104
PRK13688 PRK13688
N-acetyltransferase;
73-140 4.56e-03

N-acetyltransferase;


Pssm-ID: 237470  Cd Length: 156  Bit Score: 35.37  E-value: 4.56e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 640682786  73 DDYIDL--LFVSPDYSRQGVASALLN-TLLRQLPERvytVEASITAKPFFARHGFTvmqpqEVTA---RGEQFL 140
Cdd:PRK13688  77 QDYLELwkLEVLPKYQNRGYGEMLVDfAKSFQLPIK---TIARNKSKDFWLKLGFT-----PVEYkndEGEDPL 142
PRK07922 PRK07922
amino-acid N-acetyltransferase;
81-134 4.91e-03

amino-acid N-acetyltransferase;


Pssm-ID: 236132 [Multi-domain]  Cd Length: 169  Bit Score: 35.67  E-value: 4.91e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 640682786  81 VSPDYSRQGVASALLNTLL---RQLP-ERVY--TVEAsitakPFFARHGFTVMQPQEVTA 134
Cdd:PRK07922  78 VDPAARGRGVGHAIVERLLdvaRELGlSRVFvlTFEV-----EFFARHGFVEIDGTPVTP 132
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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