NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|644362826|ref|WP_025303894|]
View 

MULTISPECIES: enoyl-CoA hydratase/isomerase family protein [Serratia]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10787157)

enoyl-CoA hydratase/isomerase family protein similar to human ethylmalonyl-CoA decarboxylase that decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA

CATH:  3.90.226.10
Gene Ontology:  GO:0016829
PubMed:  12467702|22016388

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 9-252 2.20e-35

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


:

Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 127.21  E-value: 2.20e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   9 LRLSHAHGVMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTLIDEPHAFDELAsnap 87
Cdd:COG1024    1 VLVEREGGVATITLNRPeKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAF-CAGADLKELAAAADPEEAR---- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  88 EGLNPFQAFGELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAAgLAQCEALMGITPGGGATQYLTSRMTRGRAL 167
Cdd:COG1024   76 AFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDAR-FGLPEVRLGLIPGGGGTQRLPRLVGLARAK 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 168 EVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMPAP---DLQAGFYREHDAWAGLFAR 244
Cdd:COG1024  155 ELLLTGRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAAleaPLDEALELEAEAFAELFAS 234


                 ....*...
gi 644362826 245 PAAERLIR 252
Cdd:COG1024  235 EDAREGIA 242
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 9-252 2.20e-35

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 127.21  E-value: 2.20e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   9 LRLSHAHGVMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTLIDEPHAFDELAsnap 87
Cdd:COG1024    1 VLVEREGGVATITLNRPeKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAF-CAGADLKELAAAADPEEAR---- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  88 EGLNPFQAFGELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAAgLAQCEALMGITPGGGATQYLTSRMTRGRAL 167
Cdd:COG1024   76 AFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDAR-FGLPEVRLGLIPGGGGTQRLPRLVGLARAK 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 168 EVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMPAP---DLQAGFYREHDAWAGLFAR 244
Cdd:COG1024  155 ELLLTGRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAAleaPLDEALELEAEAFAELFAS 234


                 ....*...
gi 644362826 245 PAAERLIR 252
Cdd:COG1024  235 EDAREGIA 242
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 9-207 1.09e-31

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 116.12  E-value: 1.09e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   9 LRLSHAHGVMTIAIDNPP-VNVLDVALMSEISRLLLAVRDDPDTRVLVFQSAnPAFFIAHVDmtlIDEPHAFDELASNAP 87
Cdd:cd06558    1 VLVERDGGVATITLNRPEkRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGAD---LKELAALSDAGEEAR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  88 EGLNPFQAFGELLRSQPQVTLVKLAGLARGGGAEF-------VAaadmafaaREAAGLAQCEALMGITPGGGATQYLTSR 160
Cdd:cd06558   77 AFIRELQELLRALLRLPKPVIAAVNGAALGGGLELalacdirIA--------AEDAKFGLPEVKLGLVPGGGGTQRLPRL 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 644362826 161 MTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNI 207
Cdd:cd06558  149 VGPARARELLLTGRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 9-247 1.34e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 96.48  E-value: 1.34e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   9 LRLSHAHGVMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTlidephAFDELASNAP 87
Cdd:PRK06688   7 LLVELEDGVLTITINRPdKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAF-SAGGDIK------DFPKAPPKPP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  88 EGLNPFQAFGELLRSQPQVTLVKLAGLARGGGAE------FVAAAdmafaarEAAGLAQCEALMGITPGGGATQYLTSRM 161
Cdd:PRK06688  80 DELAPVNRFLRAIAALPKPVVAAVNGPAVGVGVSlalacdLVYAS-------ESAKFSLPFAKLGLCPDAGGSALLPRLI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 162 TRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMPA---PDLQAGFYREHDAW 238
Cdd:PRK06688 153 GRARAAEMLLLGEPLSAEEALRIGLVNRVVPAAELDAEADAQAAKLAAGPASALRYTKRAINAatlTELEEALAREAAGF 232


                 ....*....
gi 644362826 239 AGLFARPAA 247
Cdd:PRK06688 233 GRLLRTPDF 241
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 16-261 5.73e-20

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 86.26  E-value: 5.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   16 GVMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSAnPAFFIAHVDMT-LIDEPHAFDELASNapeglnPF 93
Cdd:pfam00378   5 GVAVITLNRPeAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKeMYGEGPAHQALYRE------NV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   94 QAFGELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAAgLAQCEALMGITPGGGATQYLTSRMTRGRALEVILGA 173
Cdd:pfam00378  78 LDLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNAS-FGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  174 DLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMPAP---DLQAGFYREhdawAGLFARPAAERL 250
Cdd:pfam00378 157 RRISAQEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKledALPTQLEAE----ARLFYSTFSKDD 232

                         250
                  ....*....|.
gi 644362826  251 IRGGLKAGAQT 261
Cdd:pfam00378 233 IIEGLQAFLEK 243
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 16-189 5.81e-10

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 59.47  E-value: 5.81e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   16 GVMTIAIDNP--PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDMTLIDEPHAFDELASNAPEGlnpf 93
Cdd:TIGR02441  22 DVAVVKIDSPnsKVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEG---- 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   94 QAFGELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAAG-LAQCEALMGITPGGGATQYLTSRMTRGRALEVILG 172
Cdd:TIGR02441  98 QEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLT 177

                         170
                  ....*....|....*..
gi 644362826  173 ADLIDAATAERYGWINR 189
Cdd:TIGR02441 178 GKKIRADRAKKMGIVDQ 194
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 9-252 2.20e-35

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 127.21  E-value: 2.20e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   9 LRLSHAHGVMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTLIDEPHAFDELAsnap 87
Cdd:COG1024    1 VLVEREGGVATITLNRPeKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAF-CAGADLKELAAAADPEEAR---- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  88 EGLNPFQAFGELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAAgLAQCEALMGITPGGGATQYLTSRMTRGRAL 167
Cdd:COG1024   76 AFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDAR-FGLPEVRLGLIPGGGGTQRLPRLVGLARAK 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 168 EVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMPAP---DLQAGFYREHDAWAGLFAR 244
Cdd:COG1024  155 ELLLTGRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAAleaPLDEALELEAEAFAELFAS 234


                 ....*...
gi 644362826 245 PAAERLIR 252
Cdd:COG1024  235 EDAREGIA 242
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 9-207 1.09e-31

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 116.12  E-value: 1.09e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   9 LRLSHAHGVMTIAIDNPP-VNVLDVALMSEISRLLLAVRDDPDTRVLVFQSAnPAFFIAHVDmtlIDEPHAFDELASNAP 87
Cdd:cd06558    1 VLVERDGGVATITLNRPEkRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGAD---LKELAALSDAGEEAR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  88 EGLNPFQAFGELLRSQPQVTLVKLAGLARGGGAEF-------VAaadmafaaREAAGLAQCEALMGITPGGGATQYLTSR 160
Cdd:cd06558   77 AFIRELQELLRALLRLPKPVIAAVNGAALGGGLELalacdirIA--------AEDAKFGLPEVKLGLVPGGGGTQRLPRL 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 644362826 161 MTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNI 207
Cdd:cd06558  149 VGPARARELLLTGRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 9-247 1.34e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 96.48  E-value: 1.34e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   9 LRLSHAHGVMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTlidephAFDELASNAP 87
Cdd:PRK06688   7 LLVELEDGVLTITINRPdKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAF-SAGGDIK------DFPKAPPKPP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  88 EGLNPFQAFGELLRSQPQVTLVKLAGLARGGGAE------FVAAAdmafaarEAAGLAQCEALMGITPGGGATQYLTSRM 161
Cdd:PRK06688  80 DELAPVNRFLRAIAALPKPVVAAVNGPAVGVGVSlalacdLVYAS-------ESAKFSLPFAKLGLCPDAGGSALLPRLI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 162 TRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMPA---PDLQAGFYREHDAW 238
Cdd:PRK06688 153 GRARAAEMLLLGEPLSAEEALRIGLVNRVVPAAELDAEADAQAAKLAAGPASALRYTKRAINAatlTELEEALAREAAGF 232


                 ....*....
gi 644362826 239 AGLFARPAA 247
Cdd:PRK06688 233 GRLLRTPDF 241
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 16-261 5.73e-20

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 86.26  E-value: 5.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   16 GVMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSAnPAFFIAHVDMT-LIDEPHAFDELASNapeglnPF 93
Cdd:pfam00378   5 GVAVITLNRPeAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKeMYGEGPAHQALYRE------NV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   94 QAFGELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAAgLAQCEALMGITPGGGATQYLTSRMTRGRALEVILGA 173
Cdd:pfam00378  78 LDLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNAS-FGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  174 DLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMPAP---DLQAGFYREhdawAGLFARPAAERL 250
Cdd:pfam00378 157 RRISAQEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKledALPTQLEAE----ARLFYSTFSKDD 232

                         250
                  ....*....|.
gi 644362826  251 IRGGLKAGAQT 261
Cdd:pfam00378 233 IIEGLQAFLEK 243
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 9-209 8.86e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 80.45  E-value: 8.86e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   9 LRLSHAHGVMTIAIDNPPVNVLDVALMSEISRLLLAVRDDPDTRVLVFqSANPAFFIAHVDM---TLIDEPHAFDELASN 85
Cdd:PRK07658   4 LSVRVEDHVAVITLNHPPANALSSQVLHELSELLDQVEKDDNVRVVVI-HGEGRFFSAGADIkefTSVTEAEQATELAQL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  86 APEGLNPFQAFgellrsqPQVTLVKLAGLARGGGAEFVAAADMAFAArEAAGLAQCEALMGITPGGGATQYLTSRMTRGR 165
Cdd:PRK07658  83 GQVTFERVEKF-------SKPVIAAIHGAALGGGLELAMSCHIRFAT-ESAKLGLPELNLGLIPGFAGTQRLPRYVGKAK 154

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 644362826 166 ALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAA 209
Cdd:PRK07658 155 ALEMMLTSEPITGAEALKWGLVNGVFPEETLLDDAKKLAKKIAG 198
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 16-257 3.56e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 79.01  E-value: 3.56e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  16 GVMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDMTlidEPHAFDElaSNAPEGLNPFQ 94
Cdd:PRK07657  13 HVVKITLNRPrAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLK---ERAGMNE--EQVRHAVSLIR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  95 AFGELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAArEAAGLAQCEALMGITPGGGATQYLTSRMTRGRALEVILGAD 174
Cdd:PRK07657  88 TTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAA-ESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGR 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 175 LIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMPA---PDLQAGFYREHDAWAGLFarPAAERLi 251
Cdd:PRK07657 167 RISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAISNgiqVDLHTGLQIEKQAYEGTI--PTKDRL- 243


                 ....*.
gi 644362826 252 rGGLKA 257
Cdd:PRK07657 244 -EGLQA 248
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
9-220 1.71e-16

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 77.04  E-value: 1.71e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   9 LRLSHAHGVMTIAIDNPPVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDMTLIDEPHAFDelASNAPE 88
Cdd:PRK03580   5 LHTTRNGSILEITLDRPKANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAEGEAPD--ADFGPG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  89 GLNPFQAFGELlrSQPQVTLVKlaGLARGGGAEFVAAADMAFAArEAAGLAQCEALMGITPGGGATQYLTSRMTRGRALE 168
Cdd:PRK03580  83 GFAGLTEIFDL--DKPVIAAVN--GYAFGGGFELALAADFIVCA-DNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANE 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 644362826 169 VILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQ 220
Cdd:PRK03580 158 MVMTGRRMDAEEALRWGIVNRVVPQAELMDRARELAQQLVNSAPLAIAALKE 209
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 9-234 1.81e-15

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 74.21  E-value: 1.81e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   9 LRLSHAHGVMTIAIDNPP-VNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAH--VDMTLIDEPHAFDELasn 85
Cdd:PRK08139  13 LLREDRDGVATLTLNRPQaFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHdlKEMRAARGLAYFRAL--- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  86 apeglnpFQAFGEL---LRSQPQVTLVKLAGLARGGGAEFVAaadmafaareAAGLAQCE-----ALMGI-------TPG 150
Cdd:PRK08139  90 -------FARCSRVmqaIVALPQPVIARVHGIATAAGCQLVA----------SCDLAVAAdtarfAVPGVniglfcsTPM 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 151 GGatqyLTSRMTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAmpapdlqag 230
Cdd:PRK08139 153 VA----LSRNVPRKQAMEMLLTGEFIDAATAREWGLVNRVVPADALDAAVARLAAVIAAKSPAAVRIGKEA--------- 219


                 ....
gi 644362826 231 FYRE 234
Cdd:PRK08139 220 FYRQ 223
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 8-242 1.36e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 71.49  E-value: 1.36e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   8 KLRLSHAHGVMTIAIDNPPVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDMTLI---DEPHAFdELAs 84
Cdd:PRK09076   4 ELDLEIDGHVAILTLNNPPANTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLFadgDKAVAR-EMA- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  85 napeglnpfQAFG---ELLRSQPQVTLVKLAGLARGGGAEfVAAADMAFAAREAAGLAQCEALMGITPGGGATQYLTSRM 161
Cdd:PRK09076  82 ---------RRFGeafEALSAFRGVSIAAINGYAMGGGLE-CALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLV 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 162 TRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAK---QAMPAPDLQAGFYREHDAW 238
Cdd:PRK09076 152 GEGWAKRMILCGERVDAATALRIGLVEEVVEKGEAREAALALAQKVANQSPSAVAACKtliQAARNGPRAAALALERELF 231


                 ....
gi 644362826 239 AGLF 242
Cdd:PRK09076 232 VDLF 235
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
1-217 8.50e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 66.71  E-value: 8.50e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   1 MTDTDFSKLRlshaHGVMTIAIDNPP-VNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDMtlidepHAF 79
Cdd:PRK05980   1 MTDTVLIEIR----DGIALLTLNRPEkLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADI------HEF 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  80 -DELASNAPEGLNPFQAFGELLRSQ----PQVTLVKLAGLARGGGAEfVAAADMAFAAREAAGLAQCEALMGITPGGGAT 154
Cdd:PRK05980  71 sASVAAGADVALRDFVRRGQAMTARleafPKPVIAAVNGLAFGGGCE-ITEAVHLAIASERALFAKPEIRLGMPPTFGGT 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 644362826 155 QYLTSRMTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAA 217
Cdd:PRK05980 150 QRLPRLAGRKRALELLLTGDAFSAERALEIGLVNAVVPHEELLPAARALARRIIRHSPVAVAA 212
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
5-222 1.18e-12

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 66.31  E-value: 1.18e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   5 DFSKLRLSHAHGVMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDMTLIDEphafdela 83
Cdd:PRK05809   2 ELKNVILEKEGHIAVVTINRPkALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKD-------- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  84 snapegLNPFQA--FGEL---------LRSQPQVTLVKlaGLARGGGAEfVAAADMAFAAREAAGLAQCEALMGITPGGG 152
Cdd:PRK05809  74 ------LNEEEGrkFGLLgnkvfrkleNLDKPVIAAIN--GFALGGGCE-LSMACDIRIASEKAKFGQPEVGLGITPGFG 144

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 153 ATQYLTSRMTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAM 222
Cdd:PRK05809 145 GTQRLARIVGPGKAKELIYTGDMINAEEALRIGLVNKVVEPEKLMEEAKALANKIAANAPIAVKLCKDAI 214
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
12-222 2.67e-12

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 64.99  E-value: 2.67e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  12 SHAHGVMTIAIDNPPVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTLIDEPHAFDEL-ASNApegl 90
Cdd:PRK07938   7 TPEPGIAEVTVDYPPVNALPSAGWFALADAITAAGADPDTRVVVLRAEGRGF-NAGVDIKELQATPGFTALiDANR---- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  91 NPFQAFGELLRSQPQVtLVKLAGLARGGGAEFVAAADMAFAAREAA-GLAQCE--ALmgitpgGGAT-------QYLTSR 160
Cdd:PRK07938  82 GCFAAFRAVYECAVPV-IAAVHGFCLGGGIGLVGNADVIVASDDATfGLPEVDrgAL------GAAThlqrlvpQHLMRA 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 644362826 161 MtrgralevILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAM 222
Cdd:PRK07938 155 L--------FFTAATITAAELHHFGSVEEVVPRDQLDEAALEVARKIAAKDTRVIRAAKEAL 208
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 28-219 6.31e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 64.22  E-value: 6.31e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  28 NVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMtlidephafDELASNAPEGLNPFQAFGELLRSQPQVT 107
Cdd:PRK06190  26 NALSAALRRALFAALAEADADDDVDVVVLTGADPAF-CAGLDL---------KELGGDGSAYGAQDALPNPSPAWPAMRK 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 108 LVKLA--GLARGGGAEfVAAADMAFAAREAAGLAQCEALMGITPGGGATQYLTSRMTRGRALEVILGADLIDAATAERYG 185
Cdd:PRK06190  96 PVIGAinGAAVTGGLE-LALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDAADALRAG 174

                        170       180       190
                 ....*....|....*....|....*....|....
gi 644362826 186 WINRALPAAELDDFVERLARNIAALPAGVIAAAK 219
Cdd:PRK06190 175 LVTEVVPHDELLPRARRLAASIAGNNPAAVRALK 208
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 15-241 7.73e-12

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 63.63  E-value: 7.73e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  15 HGVMTIAIDNPPV-NVLDVALMSEISRLLLAVRDDPDTRVLVFqSANPAFFIAHVDMTLIDEPHAFDELASNAPEGLNPF 93
Cdd:PRK09674  10 QRVLLLTLNRPEArNALNNALLTQLVNELEAAATDTSIGVCVI-TGNARFFAAGADLNEMAEKDLAATLNDPRPQLWQRL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  94 QAFgellrSQPQVTLVKlaGLARGGGAEFVAAADMAFAArEAAGLAQCEALMGITPGGGATQYLTSRMTRGRALEVILGA 173
Cdd:PRK09674  89 QAF-----NKPLIAAVN--GYALGAGCELALLCDIVIAG-ENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTG 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 644362826 174 DLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMPAP---DLQAGFYREHDAWAGL 241
Cdd:PRK09674 161 ESITAQQAQQAGLVSEVFPPELTLERALQLASKIARHSPLALRAAKQALRQSqevDLQAGLAQERQLFTLL 231
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 14-219 4.66e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 61.59  E-value: 4.66e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  14 AHGVMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDmtlIDEPHAFDElaSNAPEGLNP 92
Cdd:PRK06143  14 DRGVATLTIRNAgSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGAD---IKEMATLDQ--ASAEAFISR 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  93 FQAFGELLRSQPQVTLVKLAGLARGGGAEFvaaaDMAFAAREAAGLAQC---EALMGItPGGGATQYLTSRMTRGRALEV 169
Cdd:PRK06143  89 LRDLCDAVRHFPVPVIARIPGWCLGGGLEL----AAACDLRIAAHDAQFgmpEVRVGI-PSVIHAALLPRLIGWARTRWL 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 644362826 170 ILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAK 219
Cdd:PRK06143 164 LLTGETIDAAQALAWGLVDRVVPLAELDAAVERLAASLAGCGPQALRQQK 213
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 28-221 8.23e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 60.83  E-value: 8.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  28 NVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVD---MTLIDEPHAFdelasnapegLNPFQAFGELLRSQP 104
Cdd:PRK05862  26 NALNDALMDELGAALAAFDADEGIGAIVITGSEKAF-AAGADikeMADLSFMDVY----------KGDYITNWEKVARIR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 105 QVTLVKLAGLARGGGAEFVAAADMAFAArEAAGLAQCEALMGITPGGGATQYLTSRMTRGRALEVILGADLIDAATAERY 184
Cdd:PRK05862  95 KPVIAAVAGYALGGGCELAMMCDIIIAA-DTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERA 173

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 644362826 185 GWINRALPAAELDDFVERLARNIAALPAGVIAAAKQA 221
Cdd:PRK05862 174 GLVSRVVPADKLLDEALAAATTIASFSLPAVMMAKEA 210
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 28-222 8.93e-11

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 60.79  E-value: 8.93e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  28 NVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAF--------FIAHVDmtliDEPHAFDELASNapeglnpfQAFG-- 97
Cdd:PRK09120  30 NAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGDAWsagmdlkeYFRETD----AQPEILQERIRR--------EAYGww 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  98 ELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAA-GLAqcEALMGITPGGGATQYLTSRMTRGRALEVILGADLI 176
Cdd:PRK09120  98 RRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQfGLS--EINWGIPPGGGVSKAMADTVGHRDALYYIMTGETF 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 644362826 177 DAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAM 222
Cdd:PRK09120 176 TGRKAAEMGLVNESVPLAQLRARTRELAAKLLEKNPVVLRAAKDGF 221
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 7-221 3.07e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 59.28  E-value: 3.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   7 SKLRLSHAHGVMTIAIDNPPV-NVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDMTlidephafdELASN 85
Cdd:PRK06494   4 PFSTVERKGHVTIVTLNRPEVmNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLK---------EQAAG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  86 APEGLNPfQAFGELLR----SQPQVTLVKlaGLARGGGAEFVAAADMAFAArEAAGLAQCEALMGITPGGGATQYLTSRM 161
Cdd:PRK06494  75 GKRGWPE-SGFGGLTSrfdlDKPIIAAVN--GVAMGGGFELALACDLIVAA-ENATFALPEPRVGLAALAGGLHRLPRQI 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 162 TRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQA 221
Cdd:PRK06494 151 GLKRAMGMILTGRRVTAREGLELGFVNEVVPAGELLAAAERWADDILACSPLSIRASKQA 210
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 7-222 5.74e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 58.56  E-value: 5.74e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   7 SKLRLSHAHGVMTIAIDNPP-VNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDMTlidephAFDELASN 85
Cdd:PRK06127  11 GKLLAEKTGGLGRITFNNPArHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADIS------QFEESRSD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  86 aPEGLNPFQAFGE----LLRSQPQVTLVKLAGLARGGGAEfVAAADMAFAAREAAGLAQCEALMGITPGGGATQYLTSRM 161
Cdd:PRK06127  85 -AEAVAAYEQAVEaaqaALADYAKPTIACIRGYCIGGGMG-IALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLV 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 644362826 162 TRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAM 222
Cdd:PRK06127 163 GPSAAKDLFYTARRFDAAEALRIGLVHRVTAADDLETALADYAATIAGNAPLTLRAAKRAI 223
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 16-189 5.81e-10

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 59.47  E-value: 5.81e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   16 GVMTIAIDNP--PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDMTLIDEPHAFDELASNAPEGlnpf 93
Cdd:TIGR02441  22 DVAVVKIDSPnsKVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEG---- 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   94 QAFGELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAAG-LAQCEALMGITPGGGATQYLTSRMTRGRALEVILG 172
Cdd:TIGR02441  98 QEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLT 177

                         170
                  ....*....|....*..
gi 644362826  173 ADLIDAATAERYGWINR 189
Cdd:TIGR02441 178 GKKIRADRAKKMGIVDQ 194
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 13-243 1.47e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 57.37  E-value: 1.47e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  13 HAHGVMTIAIDNPPV-NVLDVALMSEISRLLLAVRDDPDTRVLVFqSANPAFFIAHVDMTLIDEPHAFDELASNAPEGLN 91
Cdd:PRK08138  14 PADGVALLRLNRPEArNALNMEVRQQLAEHFTELSEDPDIRAIVL-TGGEKVFAAGADIKEFATAGAIEMYLRHTERYWE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  92 PfqafgelLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAArEAAGLAQCEALMGITPGGGATQYLTSRMTRGRALEVIL 171
Cdd:PRK08138  93 A-------IAQCPKPVIAAVNGYALGGGCELAMHADIIVAG-ESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMAL 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 644362826 172 GADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQA----MPAPdLQAGFYREHDAWAGLFA 243
Cdd:PRK08138 165 TGCMVPAPEALAIGLVSEVVEDEQTLPRALELAREIARMPPLALAQIKEVvlagADAP-LDAALALERKAFQLLFD 239
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
5-220 2.74e-09

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 56.67  E-value: 2.74e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   5 DFSKLRLSHAHGVMTIAIDNPPV-NVLDVALMSEISRLLLAVRDDPD-TRVLVFQSANPAFFIAhvdMTLIDEPHAFDEL 82
Cdd:PRK05981   2 QFKKVTLDFDGGVAILTLDHPEVmNAVSIDMLGGLAEALDAIEDGKAeVRCLVLTGAGRGFCTG---ANLQGRGSGGRES 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  83 ASNAPEG---LNPFQAFGELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAAGLaQCEALMGITPGGGATQYLTS 159
Cdd:PRK05981  79 DSGGDAGaalETAYHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFL-QAFRRIGLVPDGGSTWLLPR 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 644362826 160 RMTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQ 220
Cdd:PRK05981 158 LVGKARAMELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELANGPTVALGLIRK 218
PLN02888 PLN02888
enoyl-CoA hydratase
 16-241 6.03e-09

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 55.53  E-value: 6.03e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  16 GVMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTlidephafdelasnAPEglNPFQ 94
Cdd:PLN02888  19 GIATITINRPkALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAF-CSGVDLT--------------AAE--EVFK 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  95 AFGELLRSQPQVTLVK--------LAGLARGGGAEfVAAADMAFAAREAAGLAQCEALMGITPGGGATQYLTSRMTRGRA 166
Cdd:PLN02888  82 GDVKDVETDPVAQMERcrkpiigaINGFAITAGFE-IALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 167 LEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMP---APDLQAGFYRE----HDAWA 239
Cdd:PLN02888 161 REVSLTAMPLTAETAERWGLVNHVVEESELLKKAREVAEAIIKNNQGMVLRYKSVINdglKLDLGHALQLEkeraHDYYN 240


                 ..
gi 644362826 240 GL 241
Cdd:PLN02888 241 GM 242
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
16-205 4.85e-08

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 53.75  E-value: 4.85e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  16 GVMTIAIDNP--PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDMTLIDEPHAFDELASNAPEGLnpf 93
Cdd:PRK11154  15 NIAVITIDVPgeKMNTLKAEFAEQVRAILKQLREDKELKGVVFISGKPDNFIAGADINMLAACKTAQEAEALARQGQ--- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  94 QAFGElLRSQPQVTLVKLAGLARGGGAEFVA---AADMAFAAREAAGLAqcEALMGITPGGGATQYLTSRMTRGRALEVI 170
Cdd:PRK11154  92 QLFAE-IEALPIPVVAAIHGACLGGGLELALachYRVCTDDPKTVLGLP--EVQLGLLPGSGGTQRLPRLIGVSTALDMI 168

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 644362826 171 LGADLIDAATAERYGWINRALPAAELDDFVERLAR 205
Cdd:PRK11154 169 LTGKQLRAKQALKLGLVDDVVPHSILLEVAVELAK 203
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
4-230 7.91e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 52.35  E-value: 7.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   4 TDFSKLRLSHAHGVMTIAIDNPPV-NVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTLI--------- 73
Cdd:PRK08272   7 DNLKTMTYEVTGRIARITLNRPEKgNAITADTPLELRAAVERADLDPGVHVILVSGAGKGF-CAGYDLSAYaegsssggg 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  74 --DEPHAFDELASNAPEGLNPFQAFGELLRSQ---------PQVTLVKLAGLARGGG------AEFVaaadmafaareaa 136
Cdd:PRK08272  86 ggAYPGKRQAVNHLPDDPWDPMIDYQMMSRFVrgfmslwhaHKPTVAKVHGYCVAGGtdialhCDQV------------- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 137 gLAQCEALMGITP----GGGATQYLTSRMTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPA 212
Cdd:PRK08272 153 -IAADDAKIGYPPtrvwGVPATGMWAYRLGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVERIAAVPV 231

                        250
                 ....*....|....*...
gi 644362826 213 GVIAAAKQAMPAPDLQAG 230
Cdd:PRK08272 232 NQLAMVKLAVNSALLQQG 249
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 7-250 1.46e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 51.26  E-value: 1.46e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   7 SKLRLSHAHGVMTIAIDNPP-VNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTLIdephaFDELASN 85
Cdd:PRK05870   3 DPVLLDVDDGVALITVNDPDrRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAF-CAGADLTAL-----GAAPGRP 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  86 APEGLNPFQAFGELLRSQPQVTLVKLAGLARGGGAEfVAAADMAFAAREAAGLAQCEALMGITPGGGATQYLTSRMTRGR 165
Cdd:PRK05870  77 AEDGLRRIYDGFLAVASCPLPTIAAVNGAAVGAGLN-LALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQV 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 166 ALEVILGADLIDAATAERYGWINRAlpAAELDDFVERLARNIAALPAGVIAAAKQAMPA----PDLQAGFYREHDAWAGL 241
Cdd:PRK05870 156 ARAALLFGMRFDAEAAVRHGLALMV--ADDPVAAALELAAGPAAAPRELVLATKASMRAtaslAQHAAAVEFELGPQAAS 233

                        250
                 ....*....|
gi 644362826 242 FARPA-AERL 250
Cdd:PRK05870 234 VQSPEfAARL 243
PLN02600 PLN02600
enoyl-CoA hydratase
 16-222 1.50e-07

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 51.34  E-value: 1.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  16 GVMTIAIDNPPV-NVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDMTlidEPHAFDelASNAPEGLNPFQ 94
Cdd:PLN02600   4 GIVELRLDRPEAkNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLK---ERRKMS--PSEVQKFVNSLR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  95 AFGELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAAgLAQCEALMGITPGGGATQYLTSRMTRGRALEVILGAD 174
Cdd:PLN02600  79 STFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAV-FGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGR 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 644362826 175 LIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAM 222
Cdd:PLN02600 158 RIGAREAASMGLVNYCVPAGEAYEKALELAQEINQKGPLAIKMAKKAI 205
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
5-222 2.06e-07

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 50.85  E-value: 2.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   5 DFSKLRLSHAHGVMTIAIDNPPVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANpAFFIAHVDM----TLIDEPHAFD 80
Cdd:PRK06495   2 MMSQLKLEVSDHVAVVTLDNPPVNALSRELRDELIAVFDEISERPDVRVVVLTGAG-KVFCAGADLkgrpDVIKGPGDLR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  81 ELASNAPEglnpfqaFGELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAArEAAGLAQCEALMGITPGGGATQYLTSr 160
Cdd:PRK06495  81 AHNRRTRE-------CFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVAS-ENAVFGLPEIDVGLAGGGKHAMRLFG- 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 644362826 161 mtRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAM 222
Cdd:PRK06495 152 --HSLTRRMMLTGYRVPAAELYRRGVIEACLPPEELMPEAMEIAREIASKSPLATRLAKDAL 211
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
17-221 3.42e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 50.34  E-value: 3.42e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  17 VMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPaFFIAHVDMtlidePHAFDELASNAPE----GLN 91
Cdd:PRK06563   9 VLLIGLDRPaKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGE-HFTAGLDL-----ADVAPKLAAGGFPfpegGID 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  92 PFQAFGELlRSQPQVTLVKlaGLARGGGAEFVAAADMAFAArEAAGLAQCEALMGITPGGGATQYLTSRMTRGRALEVIL 171
Cdd:PRK06563  83 PWGTVGRR-LSKPLVVAVQ--GYCLTLGIELMLAADIVVAA-DNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLL 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 644362826 172 GADLIDAATAERYGWINRALPAAELDDFVERLARNIA-ALPAGV---IAAAKQA 221
Cdd:PRK06563 159 TGDEFDAQEALRLGLVQEVVPPGEQLERAIELAERIArAAPLGVqatLASARAA 212
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 4-222 3.56e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 50.31  E-value: 3.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   4 TDFSKLRLSHAHGVMTIAIDNPPV-NVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTLIDEPHAFDEl 82
Cdd:PRK05995   1 MMYETLEIEQRGQVATVTLNRPDVrNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAF-CAGADLNWMKKMAGYSD- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  83 asnaPEGLNPFQAFGELLR---SQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAaGLAQCEALMGITPgggAT--QYL 157
Cdd:PRK05995  79 ----DENRADARRLADMLRaiyRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHA-VFCLSEVRLGLIP---ATisPYV 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 644362826 158 TSRMTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAM 222
Cdd:PRK05995 151 IRAMGERAARRYFLTAERFDAAEALRLGLVHEVVPAEALDAKVDELLAALVANSPQAVRAGKRLV 215
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 146-224 4.28e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 49.91  E-value: 4.28e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 644362826 146 GITPGGGATQYLTSRMTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMPA 224
Cdd:PRK08140 140 GLVPDSGGTWFLPRLVGMARALGLALLGEKLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQPTRGLALIKQAMNA 218
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 165-232 8.81e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 49.19  E-value: 8.81e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 644362826 165 RALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAM-PAPDLQaGFY 232
Cdd:PRK08290 176 KAKELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAMPPFGLRLTKRAVnQTLDAQ-GFR 243
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
14-219 9.77e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 48.90  E-value: 9.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  14 AHGVMTIAIDNPPV-NVLDVALMSEISRLLLAVRDDPDTRVLVFqSANPAFFIAHVDMTLIDEPHAFD--ELASNAPEGL 90
Cdd:PRK07468  12 ARGVATLTLNRPEKhNALSARMIAELTTAARRLAADAAVRVVVL-TGAGKSFCAGGDLGWMRAQMTADraTRIEEARRLA 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  91 NPFQAFGELlrsqPQVTLVKLAGLARGGGAEFVAAADMAFAArEAAGLAQCEALMGITPgggAT--QYLTSRMTRGRALE 168
Cdd:PRK07468  91 MMLKALNDL----PKPLIGRIQGQAFGGGVGLISVCDVAIAV-SGARFGLTETRLGLIP---ATisPYVVARMGEANARR 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 644362826 169 VILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAK 219
Cdd:PRK07468 163 VFMSARLFDAEEAVRLGLLSRVVPAERLDAAVEAEVTPYLSCAPGAVAAAK 213
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 9-222 1.44e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 48.45  E-value: 1.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   9 LRLSHAHGVMTIAIDNPPV-NVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFFIAHVDMTlidephAFDELASnaP 87
Cdd:PRK06144  10 LLLEVRGGIARITFNRPAArNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIA------QFRAFST--A 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  88 EGLNPFQAFGE----LLRSQPQVTLVKLAGLARGGGaefvaaadmafaareaAGLAQC--------EALMGI----TPGG 151
Cdd:PRK06144  82 EDAVAYERRIDrvlgALEQLRVPTIAAIAGACVGGG----------------AAIAAAcdlriatpSARFGFpiarTLGN 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 644362826 152 GATQ----YLTSRMTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAM 222
Cdd:PRK06144 146 CLSMsnlaRLVALLGAARVKDMLFTARLLEAEEALAAGLVNEVVEDAALDARADALAELLAAHAPLTLRATKEAL 220
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
1-220 4.81e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 46.91  E-value: 4.81e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   1 MTDTdfskLRLSHAHGVMTIAIDNPPV-NVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTlidephAF 79
Cdd:PRK08252   1 MSDE----VLVERRGRVLIITINRPEArNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTF-CAGMDLK------AF 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  80 deLASNAPegLNPFQAFGELLRSQPQVTLVK-LAGLARGGGAEFVAAADMAFAAREAA-GLAqcEALMGITPGGGATQYL 157
Cdd:PRK08252  70 --ARGERP--SIPGRGFGGLTERPPRKPLIAaVEGYALAGGFELALACDLIVAARDAKfGLP--EVKRGLVAAGGGLLRL 143

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 644362826 158 TSRMTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQ 220
Cdd:PRK08252 144 PRRIPYHIAMELALTGDMLTAERAHELGLVNRLTEPGQALDAALELAERIAANGPLAVAASKR 206
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
145-222 1.15e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 45.73  E-value: 1.15e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 644362826 145 MGITPGGGATQYLTSRMTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAM 222
Cdd:PRK09245 143 LGLIPGDGGAWLLPRIIGMARAAEMAFTGDAIDAATALEWGLVSRVVPADQLLPAARALAERIAANPPHALRLTKRLL 220
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 145-253 2.43e-05

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 44.57  E-value: 2.43e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 145 MGITPGGGATQYLTSRMTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMPA 224
Cdd:PRK07110 134 YGFTPGMGATAILPEKLGLALGQEMLLTARYYRGAELKKRGVPFPVLPRAEVLEKALELARSLAEKPRHSLVLLKDHLVA 213

                         90       100       110
                 ....*....|....*....|....*....|..
gi 644362826 225 P---DLQAGFYREHDAWAGLFARPAAERLIRG 253
Cdd:PRK07110 214 DrrrRLPEVIEQEVAMHEKTFHQPEVKRRIES 245
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
1-212 3.25e-05

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 44.19  E-value: 3.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   1 MTDTDFSKLRLSHAHGVMTIAIDNPP-VNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTLIDEPhaf 79
Cdd:PRK08258  11 LAGYEARHFLWEVDDGVATITLNRPErKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGNF-CSGGDVHEIIGP--- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  80 dELASNAPEGLNPFQAFGEL---LRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREA--------AGLAQCEalMGIT 148
Cdd:PRK08258  87 -LTKMDMPELLAFTRMTGDLvkaMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAktaflftrVGLAGAD--MGAC 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 644362826 149 pgggatqYLTSRMT-RGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPA 212
Cdd:PRK08258 164 -------ALLPRIIgQGRASELLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLAAGPT 221
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 168-222 1.62e-04

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 42.32  E-value: 1.62e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 644362826 168 EVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAM 222
Cdd:PRK11423 159 EMFFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEQL 213
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
99-209 2.45e-04

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 41.93  E-value: 2.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  99 LLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAAGLAQCEALMGITPGGGATQYLTSRMTRGRALEVILGADLIDA 178
Cdd:PRK08321 130 LIRFMPKVVIAVVPGWAAGGGHSLHVVCDLTLASREHARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYSA 209

                         90       100       110
                 ....*....|....*....|....*....|.
gi 644362826 179 ATAERYGWINRALPAAELDDFVERLARNIAA 209
Cdd:PRK08321 210 EEAHDMGAVNAVVPHAELETEALEWAREING 240
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 13-276 3.43e-04

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 41.40  E-value: 3.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  13 HAHGVMTIAIDNPPVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSA-NPAFFIAHVDmtlIDEPHAFDELASNAPEGLN 91
Cdd:PLN03214  18 RPGGIAVVWLAKEPVNSMTLAMWRSLDDALTALENDPTVRGVVFASGlRRDVFTAGND---IAELYAPKTSAARYAEFWL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  92 PFQAFGELLRSQPQVTLVKLAGLARGGGAEfVAAADMAFAAREAAGLAQCEALMGI-TPGGGATQYLTSRMTRGRALEVI 170
Cdd:PLN03214  95 TQTTFLVRLLRSRLATVCAIRGACPAGGCA-VSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRKVAESLL 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 171 LGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGVIAAAKQAMpapdlqagfyREH--DAWAGLFARPAae 248
Cdd:PLN03214 174 LRGRLVRPAEAKQLGLIDEVVPAAALMEAAASAMERALKLPSAARAATKALL----------REEfsAAWEAYYEEEA-- 241

                        250       260
                 ....*....|....*....|....*...
gi 644362826 249 rliRGGLKAgAQTPEGERNLEGLLRHLA 276
Cdd:PLN03214 242 ---KGGWKM-LSEPSIIKALGGVMERLS 265
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
27-198 4.20e-04

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 41.39  E-value: 4.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  27 VNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMT----LIDEPHAfdELASNAPEGLNPFQAFGELlrs 102
Cdd:PRK11730  28 VNKLDRATLASLGEALDALEAQSDLKGLLLTSAKDAF-IVGADITeflsLFAAPEE--ELSQWLHFANSIFNRLEDL--- 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 103 qPQVTLVKLAGLARGGGAEFVaaadMAFAAREAAGLAQC---EALMGITPG-GGatqylTSRMTR----GRALEVILGAD 174
Cdd:PRK11730 102 -PVPTVAAINGYALGGGCECV----LATDYRVASPDARIglpETKLGIMPGfGG-----TVRLPRligaDNALEWIAAGK 171

                        170       180
                 ....*....|....*....|....
gi 644362826 175 LIDAATAERYGWINRALPAAELDD 198
Cdd:PRK11730 172 DVRAEDALKVGAVDAVVAPEKLQE 195
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 6-219 4.73e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 40.75  E-value: 4.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   6 FSKLRLSHAHGVMTIAIDNPPV-NVLDVALMSEISRLLLAVRDDPDTRVLVFQSANpAFFIAHVDMTLIDEPHAFDelAS 84
Cdd:PRK07511   2 SAELLSRREGSTLVLTLSNPGArNALHPDMYAAGIEALNTAERDPSIRAVVLTGAG-GFFCAGGNLNRLLENRAKP--PS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  85 NAPEGLNPFQAFGELLRSQPQVTLVKLAGLARGGGAEFVAAADMAFAAREAAgLAQCEALMGITPGGGATQYLTSRMTRG 164
Cdd:PRK07511  79 VQAASIDGLHDWIRAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAK-FVMAYVKVGLTPDGGGSWFLARALPRQ 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 644362826 165 RALEVILGADLIDAATAERYGWINR-ALPAAELDDFVeRLARNIAALPAGVIAAAK 219
Cdd:PRK07511 158 LATELLLEGKPISAERLHALGVVNRlAEPGQALAEAL-ALADQLAAGSPNALARIK 212
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
2-222 1.30e-03

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 39.57  E-value: 1.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   2 TDTDFSKLRLSHAHGVMTIAIDNP-PVNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFF--IAHVDMTLIDEPHA 78
Cdd:PRK06142   1 MMTTYESFTVELADHVAQVTLNRPgKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSygIDLPAMAGVFGQLG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  79 FDELASNAPEGLNpfqafgELLRSQPQVTLVK---------LAGLARGGGAEFVAAADMafaaREAAGLAQC---EALMG 146
Cdd:PRK06142  81 KDGLARPRTDLRR------EILRLQAAINAVAdcrkpviaaVQGWCIGGGVDLISACDM----RYASADAKFsvrEVDLG 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 644362826 147 ITPGGGATQYLTSRMTRGRALEVILGADLIDAATAERYGWINRALPAAE-LDDFVERLARNIAALPAGVIAAAKQAM 222
Cdd:PRK06142 151 MVADVGSLQRLPRIIGDGHLRELALTGRDIDAAEAEKIGLVNRVYDDADaLLAAAHATAREIAAKSPLAVRGTKEVL 227
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 5-222 1.44e-03

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 39.22  E-value: 1.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   5 DFSKLRLSHAHGVMTIAIDNPP-VNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTLIDEPHAFDELA 83
Cdd:PRK08260   2 TYETIRYDVADGIATITLNRPDkLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAF-CAGADLSAGGNTFDLDAPR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  84 SNAPeglnpFQAFGELLRSQPQVT----LVKLA-------------GLARGGGAEfVAAADMAFAAREAAGLAQCEALMG 146
Cdd:PRK08260  81 TPVE-----ADEEDRADPSDDGVRdgggRVTLRifdslkpviaavnGPAVGVGAT-MTLAMDIRLASTAARFGFVFGRRG 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 644362826 147 ITPGGGATQYLTSRMTRGRALEVILGADLIDAATAERYGWINRALPAAELDDFVERLARNIAALPAGV-IAAAKQAM 222
Cdd:PRK08260 155 IVPEAASSWFLPRLVGLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADNTSPVsVALTRQMM 231
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
2-244 3.46e-03

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 38.12  E-value: 3.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826   2 TDTDFSKLRLSHAHGVMTIAIDNPP-VNVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAFfIAHVDMTlidepHAFD 80
Cdd:PRK07827   1 DTPVDTLVRYAVDGGVATLTLDSPHnRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTF-CAGADLS-----EAGG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826  81 ELASNAPEGLNPFQAFGELLRS---QPQVTLVKLAGLARGGGAEFVAAADMAFAAREAAgLAQCEALMGITPgggATQYL 157
Cdd:PRK07827  75 GGGDPYDAAVARAREMTALLRAiveLPKPVIAAIDGHVRAGGFGLVGACDIVVAGPEST-FALTEARIGVAP---AIISL 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644362826 158 T--SRMTRGRALEVILGADLIDAATAERYGWINRAlpAAELDDFVERLARNIAALPAGVIAAAKQAMPAPDLqAGFYREH 235
Cdd:PRK07827 151 TllPRLSPRAAARYYLTGEKFGAAEAARIGLVTAA--ADDVDAAVAALLADLRRGSPQGLAESKALTTAAVL-AGFDRDA 227


                 ....*....
gi 644362826 236 DAWAGLFAR 244
Cdd:PRK07827 228 EELTEESAR 236
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
1-75 7.83e-03

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 36.92  E-value: 7.83e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 644362826   1 MTDTDFSKLRLS-HAHGVMTIAIDNPPV-NVLDVALMSEISRLLLAVRDDPDTRVLVFQSANPAfFIAHVDMTLIDE 75
Cdd:PRK07327   5 ARYADYPALRFDrPPPGVLEIVLNGPGAlNAADARMHRELADIWRDVDRDPDVRVVLIRGEGKA-FSAGGDLALVEE 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH