|
Name |
Accession |
Description |
Interval |
E-value |
| FrsA |
COG1073 |
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ... |
24-286 |
7.01e-46 |
|
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];
Pssm-ID: 440691 [Multi-domain] Cd Length: 253 Bit Score: 154.69 E-value: 7.01e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 24 KHPLILLCHGFCGIR-NVLLpsFANAFTEAGFATITFDYRGFGESEGE-RGRLVPAMQteDIISVINWAEKQVCIDNQRI 101
Cdd:COG1073 36 KYPAVVVAHGNGGVKeQRAL--YAQRLAELGFNVLAFDYRGYGESEGEpREEGSPERR--DARAAVDYLRTLPGVDPERI 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 102 GLWGTSLGGGHVFSAAAQDQRVKCIVSQLAFADGEVLVTGEMNELEKA-----SFLPTLNkmaekkkntgkemfvgvtrv 176
Cdd:COG1073 112 GLLGISLGGGYALNAAATDPRVKAVILDSPFTSLEDLAAQRAKEARGAylpgvPYLPNVR-------------------- 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 177 lsdneskvffekvkgqypemdikipfLTVMETLQYKPAESAAKVQCPVLVVIAGQDSVNPPEQGRALYDAvASGTKELYE 256
Cdd:COG1073 172 --------------------------LASLLNDEFDPLAKIEKISRPLLFIHGEKDEAVPFYMSEDLYEA-AAEPKELLI 224
|
250 260 270
....*....|....*....|....*....|
gi 647242583 257 EADACHYDIYKGAfFERVAAVQTQWFKKHL 286
Cdd:COG1073 225 VPGAGHVDLYDRP-EEEYFDKLAEFFKKNL 253
|
|
| Abhydrolase_1 |
pfam00561 |
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes. |
26-269 |
1.40e-28 |
|
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
Pssm-ID: 395444 [Multi-domain] Cd Length: 245 Bit Score: 109.52 E-value: 1.40e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 26 PLILLCHGFCGIRNvLLPSFANAFTEAGFATITFDYRGFGESEGERGRlvPAMQTEDIISVINWAEKQvcIDNQRIGLWG 105
Cdd:pfam00561 1 PPVLLLHGLPGSSD-LWRKLAPALARDGFRVIALDLRGFGKSSRPKAQ--DDYRTDDLAEDLEYILEA--LGLEKVNLVG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 106 TSLGGGHVFSAAAQ-DQRVKCIVSQLAFADgeVLVTGEMNELEKASFLPTLNKMAEKKKNTGKEMFVGVTRVLSDNESKV 184
Cdd:pfam00561 76 HSMGGLIALAYAAKyPDRVKALVLLGALDP--PHELDEADRFILALFPGFFDGFVADFAPNPLGRLVAKLLALLLLRLRL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 185 FF--EKVKGQYPEMDIKIPFLTVMETLQYKPAESAAKVQC-------PVLVVIAGQDSVNPPEQGRALYDAVASgtKELY 255
Cdd:pfam00561 154 LKalPLLNKRFPSGDYALAKSLVTGALLFIETWSTELRAKflgrldePTLIIWGDQDPLVPPQALEKLAQLFPN--ARLV 231
|
250
....*....|....
gi 647242583 256 EEADACHYDIYKGA 269
Cdd:pfam00561 232 VIPDAGHFAFLEGP 245
|
|
| PLN02298 |
PLN02298 |
hydrolase, alpha/beta fold family protein |
27-254 |
4.47e-06 |
|
hydrolase, alpha/beta fold family protein
Pssm-ID: 165939 [Multi-domain] Cd Length: 330 Bit Score: 47.46 E-value: 4.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 27 LILLCHGFCGIRNVLLPSFANAFTEAGFATITFDYRGFGESEGERGrLVPAMQ--TEDIISVINWAEKQVCIDNQRIGLW 104
Cdd:PLN02298 61 LIFMVHGYGNDISWTFQSTAIFLAQMGFACFALDLEGHGRSEGLRA-YVPNVDlvVEDCLSFFNSVKQREEFQGLPRFLY 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 105 GTSLGGGhvfsaaaqdqrvKCIVSQLAFA---DGEVLVTGEMNELEK--------------ASFLPTLnKMAEKKKNTGK 167
Cdd:PLN02298 140 GESMGGA------------ICLLIHLANPegfDGAVLVAPMCKISDKirppwpipqiltfvARFLPTL-AIVPTADLLEK 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 168 EMFVGVTRVLSDNESKVFFEKvkgqyPEMDIKIPFLTVMETLQYKPAEsaakVQCPVLVVIAGQDSVNPPEQGRALYDAV 247
Cdd:PLN02298 207 SVKVPAKKIIAKRNPMRYNGK-----PRLGTVVELLRVTDYLGKKLKD----VSIPFIVLHGSADVVTDPDVSRALYEEA 277
|
....*..
gi 647242583 248 ASGTKEL 254
Cdd:PLN02298 278 KSEDKTI 284
|
|
| /NonD |
TIGR00976 |
putative hydrolase, CocE/NonD family; This model represents a protein subfamily that includes ... |
19-134 |
2.41e-05 |
|
putative hydrolase, CocE/NonD family; This model represents a protein subfamily that includes the cocaine esterase CocE, several glutaryl-7-ACA acylases, and the putative diester hydrolase NonD of Streptomyces griseus (all hydrolases). This family shows extensive, low-level similarity to a family of xaa-pro dipeptidyl-peptidases, and local similarity by PSI-BLAST to many other hydrolases. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273375 [Multi-domain] Cd Length: 550 Bit Score: 45.56 E-value: 2.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 19 PEGNIKHPLILLCHGFcgIRNVLLPSFANA-----FTEAGFATITFDYRGFGESEGERGrLVPAMQTEDIISVINWAEKQ 93
Cdd:TIGR00976 16 PAGGGPVPVILSRTPY--GKDAGLRWGLDKtepawFVAQGYAVVIQDTRGRGASEGEFD-LLGSDEAADGYDLVDWIAKQ 92
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 647242583 94 VCIDNqRIGLWGTSLGGGHVFSAAAQDQR-VKCIVSQLAFAD 134
Cdd:TIGR00976 93 PWCDG-NVGMLGVSYLAVTQLLAAVLQPPaLRAIAPQEGVWD 133
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| FrsA |
COG1073 |
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ... |
24-286 |
7.01e-46 |
|
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];
Pssm-ID: 440691 [Multi-domain] Cd Length: 253 Bit Score: 154.69 E-value: 7.01e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 24 KHPLILLCHGFCGIR-NVLLpsFANAFTEAGFATITFDYRGFGESEGE-RGRLVPAMQteDIISVINWAEKQVCIDNQRI 101
Cdd:COG1073 36 KYPAVVVAHGNGGVKeQRAL--YAQRLAELGFNVLAFDYRGYGESEGEpREEGSPERR--DARAAVDYLRTLPGVDPERI 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 102 GLWGTSLGGGHVFSAAAQDQRVKCIVSQLAFADGEVLVTGEMNELEKA-----SFLPTLNkmaekkkntgkemfvgvtrv 176
Cdd:COG1073 112 GLLGISLGGGYALNAAATDPRVKAVILDSPFTSLEDLAAQRAKEARGAylpgvPYLPNVR-------------------- 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 177 lsdneskvffekvkgqypemdikipfLTVMETLQYKPAESAAKVQCPVLVVIAGQDSVNPPEQGRALYDAvASGTKELYE 256
Cdd:COG1073 172 --------------------------LASLLNDEFDPLAKIEKISRPLLFIHGEKDEAVPFYMSEDLYEA-AAEPKELLI 224
|
250 260 270
....*....|....*....|....*....|
gi 647242583 257 EADACHYDIYKGAfFERVAAVQTQWFKKHL 286
Cdd:COG1073 225 VPGAGHVDLYDRP-EEEYFDKLAEFFKKNL 253
|
|
| DAP2 |
COG1506 |
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]; |
15-286 |
1.60e-40 |
|
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
Pssm-ID: 441115 [Multi-domain] Cd Length: 234 Bit Score: 140.54 E-value: 1.60e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 15 TFRVPEGNIKHPLILLCHGFCGIRNVLLPSFANAFTEAGFATITFDYRGFGESEGERGRLvpamQTEDIISVINWAEKQV 94
Cdd:COG1506 13 WLYLPADGKKYPVVVYVHGGPGSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGD----EVDDVLAAIDYLAARP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 95 CIDNQRIGLWGTSLGGGHVFSAAAQD-QRVKCIVSQLAFADGEVLVTGEMNELEKASFLPTLNKMAekkkntgkemfvgv 173
Cdd:COG1506 89 YVDPDRIGIYGHSYGGYMALLAAARHpDRFKAAVALAGVSDLRSYYGTTREYTERLMGGPWEDPEA-------------- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 174 trvlsdneskvffekvkgqYPEMDikipfltvmetlqykPAESAAKVQCPVLVVIAGQDSVNPPEQGRALYDAV--ASGT 251
Cdd:COG1506 155 -------------------YAARS---------------PLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALkkAGKP 200
|
250 260 270
....*....|....*....|....*....|....*..
gi 647242583 252 KEL--YEEADACHYDIYKGAFFERVaavqTQWFKKHL 286
Cdd:COG1506 201 VELlvYPGEGHGFSGAGAPDYLERI----LDFLDRHL 233
|
|
| Abhydrolase_1 |
pfam00561 |
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes. |
26-269 |
1.40e-28 |
|
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
Pssm-ID: 395444 [Multi-domain] Cd Length: 245 Bit Score: 109.52 E-value: 1.40e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 26 PLILLCHGFCGIRNvLLPSFANAFTEAGFATITFDYRGFGESEGERGRlvPAMQTEDIISVINWAEKQvcIDNQRIGLWG 105
Cdd:pfam00561 1 PPVLLLHGLPGSSD-LWRKLAPALARDGFRVIALDLRGFGKSSRPKAQ--DDYRTDDLAEDLEYILEA--LGLEKVNLVG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 106 TSLGGGHVFSAAAQ-DQRVKCIVSQLAFADgeVLVTGEMNELEKASFLPTLNKMAEKKKNTGKEMFVGVTRVLSDNESKV 184
Cdd:pfam00561 76 HSMGGLIALAYAAKyPDRVKALVLLGALDP--PHELDEADRFILALFPGFFDGFVADFAPNPLGRLVAKLLALLLLRLRL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 185 FF--EKVKGQYPEMDIKIPFLTVMETLQYKPAESAAKVQC-------PVLVVIAGQDSVNPPEQGRALYDAVASgtKELY 255
Cdd:pfam00561 154 LKalPLLNKRFPSGDYALAKSLVTGALLFIETWSTELRAKflgrldePTLIIWGDQDPLVPPQALEKLAQLFPN--ARLV 231
|
250
....*....|....
gi 647242583 256 EEADACHYDIYKGA 269
Cdd:pfam00561 232 VIPDAGHFAFLEGP 245
|
|
| PldB |
COG2267 |
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism]; |
1-284 |
1.01e-22 |
|
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
Pssm-ID: 441868 [Multi-domain] Cd Length: 221 Bit Score: 93.14 E-value: 1.01e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 1 MKITDHKLP--EGIALTFRV--PEGNIKhPLILLCHGFCGIRNVLLPsFANAFTEAGFATITFDYRGFGESEGERGRLV- 75
Cdd:COG2267 1 MTRRLVTLPtrDGLRLRGRRwrPAGSPR-GTVVLVHGLGEHSGRYAE-LAEALAAAGYAVLAFDLRGHGRSDGPRGHVDs 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 76 PAMQTEDIISVINWAEKQvciDNQRIGLWGTSLGGGHVFSAAAQ-DQRVKCIVsqlafadgevlvtgemnelekasflpt 154
Cdd:COG2267 79 FDDYVDDLRAALDALRAR---PGLPVVLLGHSMGGLIALLYAARyPDRVAGLV--------------------------- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 155 lnkmaekkkntgkemFVGvTRVLSDneskvffekvkgqyPEMDIKIPFLTVMEtlqykPAESAAKVQCPVLVVIAGQDSV 234
Cdd:COG2267 129 ---------------LLA-PAYRAD--------------PLLGPSARWLRALR-----LAEALARIDVPVLVLHGGADRV 173
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 647242583 235 NPPEQGRALYDAVASGtKELYEEADACHyDIYKGAFFERVAAVQTQWFKK 284
Cdd:COG2267 174 VPPEAARRLAARLSPD-VELVLLPGARH-ELLNEPAREEVLAAILAWLER 221
|
|
| Hydrolase_4 |
pfam12146 |
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ... |
27-258 |
5.65e-17 |
|
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.
Pssm-ID: 463473 [Multi-domain] Cd Length: 238 Bit Score: 78.02 E-value: 5.65e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 27 LILLCHGFCGIRNVLLPsFANAFTEAGFATITFDYRGFGESEGERGRlVPAMQT--EDIISVINWAEKQVCidNQRIGLW 104
Cdd:pfam12146 6 VVVLVHGLGEHSGRYAH-LADALAAQGFAVYAYDHRGHGRSDGKRGH-VPSFDDyvDDLDTFVDKIREEHP--GLPLFLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 105 GTSLGGGHVFSAAAQD-QRVKCIV-SQLAFADGEVLVTgemneLEKASFLPTLNKMAEKKKNTGKEMFVGVTRvlsDNES 182
Cdd:pfam12146 82 GHSMGGLIAALYALRYpDKVDGLIlSAPALKIKPYLAP-----PILKLLAKLLGKLFPRLRVPNNLLPDSLSR---DPEV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 183 KVFFEKVkgqyPEMDIKIP------FLTVMETLQykpaESAAKVQCPVLVVIAGQDSVNPPEQGRALYDAVASGTKEL-- 254
Cdd:pfam12146 154 VAAYAAD----PLVHGGISartlyeLLDAGERLL----RRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLkl 225
|
....
gi 647242583 255 YEEA 258
Cdd:pfam12146 226 YPGL 229
|
|
| DLH |
COG0412 |
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism]; |
9-272 |
1.03e-16 |
|
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 440181 [Multi-domain] Cd Length: 226 Bit Score: 76.93 E-value: 1.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 9 PEGIAL--TFRVPEGNIKHPLILLCHGFCGIRNVLLpSFANAFTEAGFATITFDYRGFGESEGE-------RGRLVPAMQ 79
Cdd:COG0412 11 PDGVTLpgYLARPAGGGPRPGVVVLHEIFGLNPHIR-DVARRLAAAGYVVLAPDLYGRGGPGDDpdearalMGALDPELL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 80 TEDIISVINWAEKQVCIDNQRIGLWGTSLGGGHVFSAAAQDQRVKCIVsqlafadgevlvtgemnelekaSFLPTLnkma 159
Cdd:COG0412 90 AADLRAALDWLKAQPEVDAGRVGVVGFCFGGGLALLAAARGPDLAAAV----------------------SFYGGL---- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 160 ekkkntgkemfvgvtrvlsdneskvffekvkgqypemdikipfltvmetLQYKPAESAAKVQCPVLVVIAGQDSVNPPEQ 239
Cdd:COG0412 144 -------------------------------------------------PADDLLDLAARIKAPVLLLYGEKDPLVPPEQ 174
|
250 260 270
....*....|....*....|....*....|....*
gi 647242583 240 GRALYDAV--ASGTKELYEEADACHydiykgAFFE 272
Cdd:COG0412 175 VAALEAALaaAGVDVELHVYPGAGH------GFTN 203
|
|
| YvaK |
COG1647 |
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism]; |
28-276 |
4.24e-15 |
|
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 441253 [Multi-domain] Cd Length: 246 Bit Score: 73.05 E-value: 4.24e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 28 ILLCHGFCGIRNVLLPsFANAFTEAGFATITFDYRGFGESEGERGRLVPAMQTEDIISVINWAEKQVcidnQRIGLWGTS 107
Cdd:COG1647 18 VLLLHGFTGSPAEMRP-LAEALAKAGYTVYAPRLPGHGTSPEDLLKTTWEDWLEDVEEAYEILKAGY----DKVIVIGLS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 108 LGGghVFS--AAAQDQRVKCIVSQ---LAFADgevlvtgemnelEKASFLPTLNKMAEKKKNTGKEMfvgvtrvlsdnES 182
Cdd:COG1647 93 MGG--LLAllLAARYPDVAGLVLLspaLKIDD------------PSAPLLPLLKYLARSLRGIGSDI-----------ED 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 183 KVFFEKVKGQYPemdikIPFLTVMETLQYKPAESAAKVQCPVLVVIAGQDSVNPPEQGRALYDAVASGTKELY------- 255
Cdd:COG1647 148 PEVAEYAYDRTP-----LRALAELQRLIREVRRDLPKITAPTLIIQSRKDEVVPPESARYIYERLGSPDKELVwledsgh 222
|
250 260
....*....|....*....|....*.
gi 647242583 256 -----EEADACHYDIYkgAFFERVAA 276
Cdd:COG1647 223 vitldKDREEVAEEIL--DFLERLAA 246
|
|
| MenH |
COG0596 |
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ... |
26-277 |
4.03e-10 |
|
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 440361 [Multi-domain] Cd Length: 221 Bit Score: 58.47 E-value: 4.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 26 PLILLCHGFCGIRNVLLPsFANAFtEAGFATITFDYRGFGESEGERGRLVPAMQTEDIISVINWaekqvcIDNQRIGLWG 105
Cdd:COG0596 24 PPVVLLHGLPGSSYEWRP-LIPAL-AAGYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAALLDA------LGLERVVLVG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 106 TSLGGGHVFSAAAQD-QRVKCIvsqlafadgeVLVTGEMNELEKASFLPtlnkmaekkkntgkemfvgvtrvlsdneskv 184
Cdd:COG0596 96 HSMGGMVALELAARHpERVAGL----------VLVDEVLAALAEPLRRP------------------------------- 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 185 ffekvkGQYPEmdikiPFLTVMETL-QYKPAESAAKVQCPVLVVIAGQDSVNPPEQGRALYDAVASGTKELYEEADacHY 263
Cdd:COG0596 135 ------GLAPE-----ALAALLRALaRTDLRERLARITVPTLVIWGEKDPIVPPALARRLAELLPNAELVVLPGAG--HF 201
|
250
....*....|....
gi 647242583 264 diykgAFFERVAAV 277
Cdd:COG0596 202 -----PPLEQPEAF 210
|
|
| Axe1 |
COG3458 |
Cephalosporin-C deacetylase or related acetyl esterase [Secondary metabolites biosynthesis, ... |
16-286 |
1.06e-08 |
|
Cephalosporin-C deacetylase or related acetyl esterase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442681 [Multi-domain] Cd Length: 318 Bit Score: 55.20 E-value: 1.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 16 FRVPEGNIKHPLILLCHGFCGIRNVLLPSFANAftEAGFATITFDYRGFGESEGER-------GRLVPAMQTEDIISV-- 86
Cdd:COG3458 73 LLRPKGEGPLPAVVEFHGYGGGRGLPHEDLDWA--AAGYAVLVMDTRGQGSSWGDTpdpggysGGALPGYMTRGIDDPdt 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 87 -------------INWAEKQVCIDNQRIGLWGTSLGGGHVFSAAAQDQRVKCIvsqlafadgevlvtgemnelekASFLP 153
Cdd:COG3458 151 yyyrrvyldavraVDALRSLPEVDGKRIGVTGGSQGGGLALAAAALDPRVKAA----------------------AADVP 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 154 TLNKMAEKKKNTGKEMFVGVTRVLsdnesKVFFEKVKgqypemdikipflTVMETLQYKPAESAAK-VQCPVLVVIAGQD 232
Cdd:COG3458 209 FLCDFRRALELGRAGPYPEIRRYL-----RRHREREP-------------EVFETLSYFDAVNFARrIKAPVLFSVGLMD 270
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 647242583 233 SVNPPEQGRALYDAVAsGTKEL--YEEAdacHYDIYKGAFFERvaavQTQWFKKHL 286
Cdd:COG3458 271 PVCPPSTVFAAYNALA-GPKEIlvYPFN---GHEGGGPEQQDR----QLAFLRELL 318
|
|
| Abhydrolase_6 |
pfam12697 |
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ... |
28-277 |
3.40e-08 |
|
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.
Pssm-ID: 463673 [Multi-domain] Cd Length: 211 Bit Score: 52.86 E-value: 3.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 28 ILLCHGFCGIRNVLLPSFAnafteAGFATITFDYRGFGESEGERGRLVPAMQTEDIISVInwaekqvcIDNQRIGLWGTS 107
Cdd:pfam12697 1 VVLVHGAGLSAAPLAALLA-----AGVAVLAPDLPGHGSSSPPPLDLADLADLAALLDEL--------GAARPVVLVGHS 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 108 LGGGHVFSAAAQDQRVKCIVSqlAFADGEVLVTGEMNELEKASFLPTLNKMAEKKKNtgkemfvgvtrvlsdneSKVFFE 187
Cdd:pfam12697 68 LGGAVALAAAAAALVVGVLVA--PLAAPPGLLAALLALLARLGAALAAPAWLAAESL-----------------ARGFLD 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 188 KVKGQYPEMDIKIPFLTVMETLQYKPAESAAKVQCPVLvVIAGQDSVNPPEQGRALydaVASGTKELYEEADACHYDIYK 267
Cdd:pfam12697 129 DLPADAEWAAALARLAALLAALALLPLAAWRDLPVPVL-VLAEEDRLVPELAQRLL---AALAGARLVVLPGAGHLPLDD 204
|
250
....*....|
gi 647242583 268 GaffERVAAV 277
Cdd:pfam12697 205 P---EEVAEA 211
|
|
| COG4757 |
COG4757 |
Predicted alpha/beta hydrolase [General function prediction only]; |
45-127 |
2.33e-07 |
|
Predicted alpha/beta hydrolase [General function prediction only];
Pssm-ID: 443790 [Multi-domain] Cd Length: 289 Bit Score: 51.04 E-value: 2.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 45 FANAFTEAGFATITFDYRGFGES-----EGERGRLVPAMQtEDIISVINWAEKQVciDNQRIGLWGTSLgGGHVFSAAAQ 119
Cdd:COG4757 51 FARYLAERGFAVLTYDYRGIGLSrpgslRGFDAGYRDWGE-LDLPAVLDALRARF--PGLPLLLVGHSL-GGQLLGLAPN 126
|
....*...
gi 647242583 120 DQRVKCIV 127
Cdd:COG4757 127 AERVDRLV 134
|
|
| Peptidase_S15 |
pfam02129 |
X-Pro dipeptidyl-peptidase (S15 family); |
49-135 |
1.11e-06 |
|
X-Pro dipeptidyl-peptidase (S15 family);
Pssm-ID: 396621 [Multi-domain] Cd Length: 264 Bit Score: 48.88 E-value: 1.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 49 FTEAGFATITFDYRGFGESEGERgrlVPAMQTE--DIISVINWAEKQV-CidNQRIGLWGTSLGGGHVFSAAAQDQ-RVK 124
Cdd:pfam02129 47 FAARGYAVVYQDVRGTGGSEGVF---TVGGPQEaaDGKDVIDWLAGQPwC--NGKVGMTGISYLGTTQLAAAATGPpGLK 121
|
90
....*....|.
gi 647242583 125 CIVSQLAFADG 135
Cdd:pfam02129 122 AIAPESGISDL 132
|
|
| Peptidase_S9 |
pfam00326 |
Prolyl oligopeptidase family; |
49-134 |
1.19e-06 |
|
Prolyl oligopeptidase family;
Pssm-ID: 459761 [Multi-domain] Cd Length: 213 Bit Score: 48.38 E-value: 1.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 49 FTEAGFATITFDYRG---FGESEGERGRLVPAMQT-EDIISVINWAEKQVCIDNQRIGLWGTSLGGGHVFSAAAQDQRV- 123
Cdd:pfam00326 10 LADRGYVVAIANGRGsggYGEAFHDAGKGDLGQNEfDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTGAALNQRPDLf 89
|
90
....*....|.
gi 647242583 124 KCIVSQLAFAD 134
Cdd:pfam00326 90 KAAVAHVPVVD 100
|
|
| COG2945 |
COG2945 |
Alpha/beta superfamily hydrolase [General function prediction only]; |
18-93 |
2.42e-06 |
|
Alpha/beta superfamily hydrolase [General function prediction only];
Pssm-ID: 442188 [Multi-domain] Cd Length: 201 Bit Score: 47.08 E-value: 2.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 18 VPEGNIKhPLILLCH------GFcgIRNVLLPSFANAFTEAGFATITFDYRGFGESEGE--RGRLvpamQTEDIISVINW 89
Cdd:COG2945 17 LPEGPPR-GVALILHphplfgGT--MDNKVVYTLARALVAAGFAVLRFNFRGVGRSEGEfdEGRG----ELDDAAAALDW 89
|
....
gi 647242583 90 AEKQ 93
Cdd:COG2945 90 LRAQ 93
|
|
| COG4188 |
COG4188 |
Predicted dienelactone hydrolase [General function prediction only]; |
24-286 |
2.45e-06 |
|
Predicted dienelactone hydrolase [General function prediction only];
Pssm-ID: 443342 [Multi-domain] Cd Length: 326 Bit Score: 48.18 E-value: 2.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 24 KHPLILLCHGFCGIRNVLLPsFANAFTEAGFATITFDYRG------FGESEGERGRLVPA---MQTEDIISVINWAEKQV 94
Cdd:COG4188 61 PFPLVVLSHGLGGSREGYAY-LAEHLASHGYVVAAPDHPGsnaadlSAALDGLADALDPEelwERPLDLSFVLDQLLALN 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 95 C--------IDNQRIGLWGTSLGG-------GHVFSAAAQDQRVK------CIVSQLA-----FADGEVlvtgemneleK 148
Cdd:COG4188 140 KsdpplagrLDLDRIGVIGHSLGGytalalaGARLDFAALRQYCGknpdlqCRALDLPrlaydLRDPRI----------K 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 149 ASFL--PTLnkmaekkkntgkemfvgvtrvlsdneSKVFFEkvkgqypemdikipfltvmetlqykpaESAAKVQCPVLV 226
Cdd:COG4188 210 AVVAlaPGG--------------------------SGLFGE---------------------------EGLAAITIPVLL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 227 VIAGQDSVNP-PEQGRALYDAVASGTKELYEEADACHYDI-------------YKGAFFERVAAVQ------TQWFKKHL 286
Cdd:COG4188 237 VAGSADDVTPaPDEQIRPFDLLPGADKYLLTLEGATHFSFldpctpgaailpePDPPGPDRAAIHEylnalsLAFFDAYL 316
|
|
| PLN02298 |
PLN02298 |
hydrolase, alpha/beta fold family protein |
27-254 |
4.47e-06 |
|
hydrolase, alpha/beta fold family protein
Pssm-ID: 165939 [Multi-domain] Cd Length: 330 Bit Score: 47.46 E-value: 4.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 27 LILLCHGFCGIRNVLLPSFANAFTEAGFATITFDYRGFGESEGERGrLVPAMQ--TEDIISVINWAEKQVCIDNQRIGLW 104
Cdd:PLN02298 61 LIFMVHGYGNDISWTFQSTAIFLAQMGFACFALDLEGHGRSEGLRA-YVPNVDlvVEDCLSFFNSVKQREEFQGLPRFLY 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 105 GTSLGGGhvfsaaaqdqrvKCIVSQLAFA---DGEVLVTGEMNELEK--------------ASFLPTLnKMAEKKKNTGK 167
Cdd:PLN02298 140 GESMGGA------------ICLLIHLANPegfDGAVLVAPMCKISDKirppwpipqiltfvARFLPTL-AIVPTADLLEK 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 168 EMFVGVTRVLSDNESKVFFEKvkgqyPEMDIKIPFLTVMETLQYKPAEsaakVQCPVLVVIAGQDSVNPPEQGRALYDAV 247
Cdd:PLN02298 207 SVKVPAKKIIAKRNPMRYNGK-----PRLGTVVELLRVTDYLGKKLKD----VSIPFIVLHGSADVVTDPDVSRALYEEA 277
|
....*..
gi 647242583 248 ASGTKEL 254
Cdd:PLN02298 278 KSEDKTI 284
|
|
| Aes |
COG0657 |
Acetyl esterase/lipase [Lipid transport and metabolism]; |
16-133 |
1.45e-05 |
|
Acetyl esterase/lipase [Lipid transport and metabolism];
Pssm-ID: 440422 [Multi-domain] Cd Length: 207 Bit Score: 44.86 E-value: 1.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 16 FRVPEGNIKHPLILLCHG----FCGIRNV--LLPSFANAfteAGFATITFDYRgfgesegergrLVPA----MQTEDIIS 85
Cdd:COG0657 4 YRPAGAKGPLPVVVYFHGggwvSGSKDTHdpLARRLAAR---AGAAVVSVDYR-----------LAPEhpfpAALEDAYA 69
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 647242583 86 VINWAEKQVC---IDNQRIGLWGTSLGGGHVFSAA--AQDQRVKCIVSQLAFA 133
Cdd:COG0657 70 ALRWLRANAAelgIDPDRIAVAGDSAGGHLAAALAlrARDRGGPRPAAQVLIY 122
|
|
| YheT |
COG0429 |
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; |
8-110 |
2.03e-05 |
|
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
Pssm-ID: 440198 [Multi-domain] Cd Length: 323 Bit Score: 45.13 E-value: 2.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 8 LPEG--IALTFRVPEGNIKhPLILLCHGFCG------IRnvllpSFANAFTEAGFATITFDYRGFGeseGERGRLVPAM- 78
Cdd:COG0429 43 LPDGdfVDLDWSDPPAPSK-PLVVLLHGLEGssdshyAR-----GLARALYARGWDVVRLNFRGCG---GEPNLLPRLYh 113
|
90 100 110
....*....|....*....|....*....|....
gi 647242583 79 --QTEDIISVINWAEKQVCidNQRIGLWGTSLGG 110
Cdd:COG0429 114 sgDTEDLVWVLAHLRARYP--YAPLYAVGFSLGG 145
|
|
| /NonD |
TIGR00976 |
putative hydrolase, CocE/NonD family; This model represents a protein subfamily that includes ... |
19-134 |
2.41e-05 |
|
putative hydrolase, CocE/NonD family; This model represents a protein subfamily that includes the cocaine esterase CocE, several glutaryl-7-ACA acylases, and the putative diester hydrolase NonD of Streptomyces griseus (all hydrolases). This family shows extensive, low-level similarity to a family of xaa-pro dipeptidyl-peptidases, and local similarity by PSI-BLAST to many other hydrolases. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273375 [Multi-domain] Cd Length: 550 Bit Score: 45.56 E-value: 2.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 19 PEGNIKHPLILLCHGFcgIRNVLLPSFANA-----FTEAGFATITFDYRGFGESEGERGrLVPAMQTEDIISVINWAEKQ 93
Cdd:TIGR00976 16 PAGGGPVPVILSRTPY--GKDAGLRWGLDKtepawFVAQGYAVVIQDTRGRGASEGEFD-LLGSDEAADGYDLVDWIAKQ 92
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 647242583 94 VCIDNqRIGLWGTSLGGGHVFSAAAQDQR-VKCIVSQLAFAD 134
Cdd:TIGR00976 93 PWCDG-NVGMLGVSYLAVTQLLAAVLQPPaLRAIAPQEGVWD 133
|
|
| hydr1_PEP |
TIGR03100 |
exosortase A system-associated hydrolase 1; This group of proteins are members of the alpha ... |
45-127 |
3.08e-05 |
|
exosortase A system-associated hydrolase 1; This group of proteins are members of the alpha/beta hydrolase superfamily. These proteins are generally found in genomes containing the exosortase/PEP-CTERM protein expoert system, specifically the type 1 variant of this system described by the Genome Property GenProp0652. When found in this context they are invariably present in the vicinity of a second, relatively unrelated enzyme (ortholog 2, TIGR03101) of the same superfamily.
Pssm-ID: 132144 Cd Length: 274 Bit Score: 44.42 E-value: 3.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 45 FANAFTEAGFATITFDYRGFGESEGERGRLVPAMqtEDIISVINwAEKQVCIDNQRIGLWGTSLGGGHVFSAAAQDQRVK 124
Cdd:TIGR03100 49 LARRLAEAGFPVLRFDYRGMGDSEGENLGFEGID--ADIAAAID-AFREAAPHLRRIVAWGLCDAASAALLYAPADLRVA 125
|
...
gi 647242583 125 CIV 127
Cdd:TIGR03100 126 GLV 128
|
|
| hydr2_PEP |
TIGR03101 |
exosortase A system-associated hydrolase 2; This group of proteins are members of the alpha ... |
16-118 |
1.62e-04 |
|
exosortase A system-associated hydrolase 2; This group of proteins are members of the alpha/beta hydrolase superfamily. These proteins are generally found in genomes containing the exosortase/PEP-CTERM protein expoert system, specifically the type 1 variant of this system described by the Genome Property GenProp0652. When found in this context they are invariably present in the vicinity of a second, relatively unrelated enzyme (ortholog 1, TIGR03100) of the same superfamily.
Pssm-ID: 274428 Cd Length: 266 Bit Score: 42.11 E-value: 1.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 16 FRVPEGNIKHPLILLCHGFC-----GIRNVLLPsfANAFTEAGFATITFDYRGFGESEGERGRLVPAMQTEDIISVINWA 90
Cdd:TIGR03101 16 YHPPVAVGPRGVVIYLPPFAeemnkSRRMVALQ--ARAFAAGGFGVLQIDLYGCGDSAGDFAAARWDVWKEDVAAAYRWL 93
|
90 100
....*....|....*....|....*...
gi 647242583 91 EKQVCidnQRIGLWGTSLGGGHVFSAAA 118
Cdd:TIGR03101 94 IEQGH---PPVTLWGLRLGALLALDAAN 118
|
|
| BD-FAE |
pfam20434 |
BD-FAE; This family represents a novel bifunctional feruloyl and acetyl xylan esterase (BD-FAE, ... |
47-112 |
2.36e-04 |
|
BD-FAE; This family represents a novel bifunctional feruloyl and acetyl xylan esterase (BD-FAE, previously known as bifunctional carbohydrate esterase (CE)), which is active on complex natural xylans and was identified as the basis of a monophyletic clade gathering all homologs identified in PULs (polysaccharide utilization loci) predicted to act on xylan. It adopts an alpha-beta-hydrolase fold with the catalytic triad Ser-Asp-His. This new family of proteins is a new candidate for biomass processing due to its capacity to remove ferulic acid and acetic acid from natural corn and birchwood xylan substrates.
Pssm-ID: 466583 [Multi-domain] Cd Length: 215 Bit Score: 41.40 E-value: 2.36e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 647242583 47 NAFTEAGFATITFDYRGFGESegergrLVPAmQTEDIISVINW----AEKqVCIDNQRIGLWGTSlGGGH 112
Cdd:pfam20434 41 KALLKAGYAVASINYRLSTDA------KFPA-QIQDVKAAIRFlranAAK-YGIDTNKIALMGFS-AGGH 101
|
|
| |
