|
Name |
Accession |
Description |
Interval |
E-value |
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
222-568 |
1.51e-82 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 262.81 E-value: 1.51e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 222 RIREALTAAHERFMTVLESLDDTISVVADTPNGTELLFANRTYRRLWGSEAHGHTLLYNAATAHHENDPLANNELYIAQI 301
Cdd:COG4191 10 LLLALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 302 GAWFEVQHRTLNWTDGRKVRLQVARDISQRREYEQKLSAQQEKVQLSGRLSTLGEMASSLAHELNQPLTAIVNYNSAIAA 381
Cdd:COG4191 90 LEALLLLLLAALDAEENAELEELERDITELERAEEELRELQEQLVQSEKLAALGELAAGIAHEINNPLAAILGNAELLRR 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 382 LIKsEHLDQERLLQVLDKSVSQAERAGRIIGRIRDFVRRNEPERQAVKIDTIVENTMDLAFFESRKYSKQIEVNLPEDLP 461
Cdd:COG4191 170 RLE-DEPDPEELREALERILEGAERAAEIVRSLRAFSRRDEEEREPVDLNELIDEALELLRPRLKARGIEVELDLPPDLP 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 462 EVYADPILIEQVLLNLVKNGIEAMSQSEHETLYVNISQVGLEIQVQVIDSGHGLKDP--ERLFEPFYSTKK--EGLGIGL 537
Cdd:COG4191 249 PVLGDPGQLEQVLLNLLINAIDAMEEGEGGRITISTRREGDYVVISVRDNGPGIPPEvlERIFEPFFTTKPvgKGTGLGL 328
|
330 340 350
....*....|....*....|....*....|.
gi 648465101 538 NICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:COG4191 329 SISYGIVEKHGGRIEVESEPGGGTTFTITLP 359
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
101-576 |
2.34e-69 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 228.19 E-value: 2.34e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 101 LETTFRRAMEnSMSTGMRVLDLQGRVVYVNPAFCRMVGWNESELLGT----LFPYPYWVEDKFEQhekyldiVLSGKTPS 176
Cdd:COG3852 5 SEELLRAILD-SLPDAVIVLDADGRITYVNPAAERLLGLSAEELLGRplaeLFPEDSPLRELLER-------ALAEGQPV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 177 SGMEMEAKRRDGSIFTARLYVSPLMDPNGEQiGWMTSMTDITEPKRIrealtaaherfmtvleslddtisvvadtpngte 256
Cdd:COG3852 77 TEREVTLRRKDGEERPVDVSVSPLRDAEGEG-GVLLVLRDITERKRL--------------------------------- 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 257 llfanrtyrrlwgseahghtllynaatahhendplannelyiaqigawfevqhrtlnwtdgrkvrlqvardisqrreyeq 336
Cdd:COG3852 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 337 klsaqQEKVQLSGRLSTLGEMASSLAHELNQPLTAIVNYnsaiAALIKSEhLDQERLLQVLDKSVSQAERAGRIIGRIRD 416
Cdd:COG3852 123 -----ERELRRAEKLAAVGELAAGLAHEIRNPLTGIRGA----AQLLERE-LPDDELREYTQLIIEEADRLNNLVDRLLS 192
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 417 FVRRNEPERQAVKIDTIVENTMDLAFFESRKySKQIEVNLPEDLPEVYADPILIEQVLLNLVKNGIEAMSQ--------S 488
Cdd:COG3852 193 FSRPRPPEREPVNLHEVLERVLELLRAEAPK-NIRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPEggtitirtR 271
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 489 EHETLYVNISQVGLEIQVQVIDSGHGLkDPE---RLFEPFYSTKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTF 565
Cdd:COG3852 272 VERQVTLGGLRPRLYVRIEVIDNGPGI-PEEildRIFEPFFTTKEKGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFRI 350
|
490
....*....|.
gi 648465101 566 RIPCYRKADNS 576
Cdd:COG3852 351 YLPLEQAEEEP 361
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
92-573 |
9.58e-68 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 227.94 E-value: 9.58e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 92 RSEAEEQLF-LETTFRRAMENsMSTGMRVLDLQGRVVYVNPAFCRMVGWNESELLGTLFpYPYWVEDKFEQHEKYLDIVL 170
Cdd:COG5809 3 SSKMELQLRkSEQRFRSLFEN-APDAILILDLEGKILKVNPAAERIFGYTEDELLGTNI-LDFLHPDDEKELREILKLLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 171 SGKTPSsGMEMEAKRRDGSIFTARLYVSPLMDPNGEQIGWMTSMTDITEPKRIREALTAAHERFMTVLESLDDTISVVAD 250
Cdd:COG5809 81 EGESRD-ELEFELRHKNGKRLEFSSKLSPIFDQNGDIEGMLAISRDITERKRMEEALRESEEKFRLIFNHSPDGIIVTDL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 251 TPNgteLLFANRTYRRLWG---SEAHGHTLL--------YNAATAHHE---NDPLANNEL-YIAQIGAWFEVQHR--TLN 313
Cdd:COG5809 160 DGR---IIYANPAACKLLGisiEELIGKSILelihsddqENVAAFISQllkDGGIAQGEVrFWTKDGRWRLLEASgaPIK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 314 WTDGRKVRLQVARDISQRREYEQKLSAQQekvqlsgRLSTLGEMASSLAHELNQPLTAIVNYnsaIAALIKSEHLDQERL 393
Cdd:COG5809 237 KNGEVDGIVIIFRDITERKKLEELLRKSE-------KLSVVGELAAGIAHEIRNPLTSLKGF---IQLLKDTIDEEQKTY 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 394 LQVLDKSVsqaERAGRIIGRIRDFVRRNEPERQAVKIDTIVENTMDLafFESRKYSK--QIEVNLPEDLPEVYADPILIE 471
Cdd:COG5809 307 LDIMLSEL---DRIESIISEFLVLAKPQAIKYEPKDLNTLIEEVIPL--LQPQALLKnvQIELELEDDIPDILGDENQLK 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 472 QVLLNLVKNGIEAMSqsEHETLYVNISQVGLE-IQVQVIDSGHGL--KDPERLFEPFYSTKKEGLGIGLNICRSIIESHR 548
Cdd:COG5809 382 QVFINLLKNAIEAMP--EGGNITIETKAEDDDkVVISVTDEGCGIpeERLKKLGEPFYTTKEKGTGLGLMVSYKIIEEHG 459
|
490 500
....*....|....*....|....*
gi 648465101 549 GRLWAENNPSGGTIFTFRIPCYRKA 573
Cdd:COG5809 460 GKITVESEVGKGTTFSITLPIKLSE 484
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
221-568 |
1.35e-62 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 212.13 E-value: 1.35e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 221 KRIREALTAAHERFMTVLESLDDTISVVadTPNGTeLLFANRTYRRLWG---SEAHGHTLlynaatahHENDPLANNELY 297
Cdd:COG5000 79 KEQREELEERRRYLETILENLPAGVIVL--DADGR-ITLANPAAERLLGiplEELIGKPL--------EELLPELDLAEL 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 298 IAQIGAWFEVQHRTLNWTDGRKVRLQVARDISQR-----REYEQKLSAQqekvqlsgRLSTLGEMASSLAHELNQPLTAI 372
Cdd:COG5000 148 LREALERGWQEEIELTRDGRRTLLVRASPLRDDGyvivfDDITELLRAE--------RLAAWGELARRIAHEIKNPLTPI 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 373 vnynSAIAALIKSEHL-----DQERLLQVLDKSVSQAERAGRIIGRIRDFVRRNEPERQAVKIDTIVENTMDLAFFESRK 447
Cdd:COG5000 220 ----QLSAERLRRKLAdkleeDREDLERALDTIIRQVDRLKRIVDEFLDFARLPEPQLEPVDLNELLREVLALYEPALKE 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 448 YSKQIEVNLPEDLPEVYADPILIEQVLLNLVKNGIEAMsqSEHETLYVNISQVGLEIQVQVIDSGHGL--KDPERLFEPF 525
Cdd:COG5000 296 KDIRLELDLDPDLPEVLADRDQLEQVLINLLKNAIEAI--EEGGEIEVSTRREDGRVRIEVSDNGPGIpeEVLERIFEPF 373
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 648465101 526 YSTKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:COG5000 374 FTTKPKGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLP 416
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
111-568 |
3.34e-58 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 202.65 E-value: 3.34e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 111 NSMSTGMRVLDLQGRVVYVNPAFCRMVGWNESELLGTLFP------YPYWVEDKFEQHEKYLDivlsgktpsSGMEMEAK 184
Cdd:COG5805 41 ENLPDAIIAVNREGKVIYINPAMEKLLGYTSEEIIGKTIFdflekeYHYRVKTRIERLQKGYD---------VVMIEQIY 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 185 RRDGSIFTARLYVSPLMDPNGEQIGWMTSmtDITEPKRIREALTAAHERFMTVLESLDDTISVVADtpNGTeLLFANRTY 264
Cdd:COG5805 112 CKDGELIYVEVKLFPIYNQNGQAAILALR--DITKKKKIEEILQEQEERLQTLIENSPDLICVIDT--DGR-ILFINESI 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 265 RRLWG---SEAHGHTLLYNAATAHHENDPLANNElyIAQIGAWFEVQHRTLNW----------------TDGRKVRLQV- 324
Cdd:COG5805 187 ERLFGaprEELIGKNLLELLHPCDKEEFKERIES--ITEVWQEFIIEREIITKdgriryfeavivplidTDGSVKGILVi 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 325 ARDISQRREYEQKLsAQQEKvqlsgrLSTLGEMASSLAHELNQPLTAIVNYNSaiaaLIKSEHLDQERLLQVLdksVSQA 404
Cdd:COG5805 265 LRDITEKKEAEELM-ARSEK------LSIAGQLAAGIAHEIRNPLTSIKGFLQ----LLQPGIEDKEEYFDIM---LSEL 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 405 ERAGRIIGRIRDFVRRNEPERQAVKIDTIVENTMDLAFFESRKYSKQIEVNLPEDLPEVYADPILIEQVLLNLVKNGIEA 484
Cdd:COG5805 331 DRIESIISEFLALAKPQAVNKEKENINELIQDVVTLLETEAILHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIEA 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 485 MSQSEheTLYVNISQVGLEIQVQVIDSGHGLkDPERL---FEPFYSTKKEGLGIGLNICRSIIESHRGRLWAENNPSGGT 561
Cdd:COG5805 411 MPNGG--TITIHTEEEDNSVIIRVIDEGIGI-PEERLkklGEPFFTTKEKGTGLGLMVSYKIIENHNGTIDIDSKVGKGT 487
|
....*..
gi 648465101 562 IFTFRIP 568
Cdd:COG5805 488 TFTITLP 494
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
274-570 |
7.62e-53 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 184.22 E-value: 7.62e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 274 GHTLLYNAATAHHendplaNNELYIAQIGAWFEVQHRTLNWTDGRKVRLQVARDISQRREYEQKLSAQQekvqlsgRLST 353
Cdd:COG5807 80 KDEQLYNKEAFDR------IEISYLTKNGEFDEIIYPIYYKDGVILGLITVYRDITKRKEAEDKLLRSE-------KLSV 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 354 LGEMASSLAHELNQPLTAIvnynSAIAALIKSEHLDQERlLQVLDKSVSQAERAGRIIGRIRDFVRRNEPERQAVKIDTI 433
Cdd:COG5807 147 AGELAAGIAHEIRNPLTSI----KGFLQLLQESREDSER-EEYFNIIISEIDRINTIITELLVLSKPKKFNFKKLNLNDV 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 434 VENTMDLAFFESRKYSKQIEVNLPEDLPEVYADPILIEQVLLNLVKNGIEAMSQSehETLYVNISQVGLEIQVQVIDSGH 513
Cdd:COG5807 222 LEDVIALLSTEAILKNISIKYDLADDEPVINGDKNQLKQVFINLIKNAIEAMETG--GNITIKTYVEGDFVVISVKDEGI 299
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 648465101 514 GL--KDPERLFEPFYSTKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIPCY 570
Cdd:COG5807 300 GIpeEVLEKIGEPFFTTKEEGTGLGLSICKKIIEEHNGTIEVESKPGKGTTFTIYLPLY 358
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
337-568 |
2.85e-50 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 173.55 E-value: 2.85e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 337 KLSAQQEKVQLSGRLstLGEMASSLAHELNQPLTAIvnyNSAIAALIKSEHLDQERLLQVLDKSVSQAERAGRIIGRIRD 416
Cdd:COG2205 1 ELEEALEELEELERL--KSEFLANVSHELRTPLTSI---LGAAELLLDEEDLSPEERRELLEIIRESAERLLRLIEDLLD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 417 FVR----RNEPERQAVKIDTIVENTMDLAFFESRKYSKQIEVNLPEDLPEVYADPILIEQVLLNLVKNGIEAMSqsEHET 492
Cdd:COG2205 76 LSRlesgKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSP--PGGT 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 493 LYVNISQVGLEIQVQVIDSGHGL--KDPERLFEPFY----STKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFR 566
Cdd:COG2205 154 ITISARREGDGVRISVSDNGPGIpeEELERIFERFYrgdnSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVT 233
|
..
gi 648465101 567 IP 568
Cdd:COG2205 234 LP 235
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
296-568 |
2.44e-45 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 163.16 E-value: 2.44e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 296 LYIAQIGAWFEVQHRTLNWTDGRKVRLQVARDISQRREYEQKLSAQQEKVQLSGRLSTLGEMASSLAHELNQPLTAIVNY 375
Cdd:COG0642 52 LLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGY 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 376 nsaIAALIKSEHLDQERLLQVLDKSVsqaERAGRIIGRIRDFVR----RNEPERQAVKIDTIVENTMDLAFFESRKYSKQ 451
Cdd:COG0642 132 ---LELLLEELDEEQREYLETILRSA---DRLLRLINDLLDLSRleagKLELEPEPVDLAELLEEVVELFRPLAEEKGIE 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 452 IEVNLPEDLPEVYADPILIEQVLLNLVKNGIEAMSqsEHETLYVNISQVGLEIQVQVIDSGHGL--KDPERLFEPFYSTK 529
Cdd:COG0642 206 LELDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTP--EGGTVTVSVRREGDRVRISVEDTGPGIppEDLERIFEPFFRTD 283
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 648465101 530 K----EGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:COG0642 284 PsrrgGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTLP 326
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
222-572 |
6.39e-44 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 160.87 E-value: 6.39e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 222 RIREALTAAHERFMTVLESLDDTISVVADTPNGTELLFANRTYRRLWGSEAHGHTLLYNAATAHHENDPLANNELYIAQI 301
Cdd:COG5002 46 LLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 302 GAWFEVQHRTLNWTDGRKVRLQVA---RDISQRREYEQKLSaqqekvqlsgrlstlgEMASSLAHELNQPLTAIvnyNSA 378
Cdd:COG5002 126 LLLLLLGRLSLRLSALLLGLLLLAaveRDITELERLEQMRR----------------EFVANVSHELRTPLTSI---RGY 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 379 IAALIKSEHLDQERLLQVLDKSVSQAERAGRIIGRIRDFVR----RNEPERQAVKIDTIVENTMDLAFFESRKYSKQIEV 454
Cdd:COG5002 187 LELLLDGAADDPEERREYLEIILEEAERLSRLVNDLLDLSRlesgELKLEKEPVDLAELLEEVVEELRPLAEEKGIELEL 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 455 NLPEDLPEVYADPILIEQVLLNLVKNGIEAMSqsEHETLYVNISQVGLEIQVQVIDSGHGL--KDPERLFEPFY------ 526
Cdd:COG5002 267 DLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTP--EGGTITVSLREEDDQVRISVRDTGIGIpeEDLPRIFERFYrvdksr 344
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 648465101 527 STKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIPCYRK 572
Cdd:COG5002 345 SRETGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITLPLARE 390
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
328-551 |
2.98e-40 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 155.23 E-value: 2.98e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 328 ISQRREYEQKLSAQQEKVQLSGRLSTLGEMASSLAHELNQPLTAIVNY-NSAIAALIKSehlDQERLLQVLDKSVSQAER 406
Cdd:COG4192 407 IEERKRIEKNLRQTQDELIQAAKMAVVGQTMTSLAHELNQPLNAMSMYlFSAKKALEQE---NYAQLPTSLDKIEGLIER 483
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 407 AGRIIGRIRDFVRRNEPERQAVKIDTIVENTMDLafFESRKYSKQIEVNLPEDLPeVYADPILIEQVLLNLVKNGIEAMS 486
Cdd:COG4192 484 MDKIIKSLRQFSRKSDTPLQPVDLRQVIEQAWEL--VESRAKPQQITLHIPDDLM-VQGDQVLLEQVLVNLLVNALDAVA 560
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 648465101 487 qsEHETLYVNISQVGLEIQVQVIDSGHGLKDPERLFEPFYSTKKEGLGIGLNICRSIIESHRGRL 551
Cdd:COG4192 561 --TQPQISVDLLSNAENLRVAISDNGNGWPLVDKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDL 623
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
326-568 |
2.14e-39 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 152.43 E-value: 2.14e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 326 RDISQRREYEQKLsAQQEkvqlsgRLSTLGEMASSLAHELNQPLTAIVNYnsaiaalikSEHLDQERLLQVLDKSVS--- 402
Cdd:PRK11360 369 SDLTERKRLQRRV-ARQE------RLAALGELVAGVAHEIRNPLTAIRGY---------VQIWRQQTSDPPSQEYLSvvl 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 403 -QAERAGRIIGRIRDFVRRNEPERQAVKIDTIVENTmdLAFFESRKYSK--QIEVNLPEDLPEVYADPILIEQVLLNLVK 479
Cdd:PRK11360 433 rEVDRLNKVIDQLLEFSRPRESQWQPVSLNALVEEV--LQLFQTAGVQArvDFETELDNELPPIWADPELLKQVLLNILI 510
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 480 NGIEAMSQSEheTLYVNISQVG-LEIQVQVIDSGHGLkDPE---RLFEPFYSTKKEGLGIGLNICRSIIESHRGRLWAEN 555
Cdd:PRK11360 511 NAVQAISARG--KIRIRTWQYSdGQVAVSIEDNGCGI-DPEllkKIFDPFFTTKAKGTGLGLALSQRIINAHGGDIEVES 587
|
250
....*....|...
gi 648465101 556 NPSGGTIFTFRIP 568
Cdd:PRK11360 588 EPGVGTTFTLYLP 600
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
470-568 |
2.39e-39 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 139.45 E-value: 2.39e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 470 IEQVLLNLVKNGIEAMSQSEHET--LYVNISQVGL-EIQVQVIDSGHGLKD--PERLFEPFYSTKKEGLGIGLNICRSII 544
Cdd:cd16920 1 IQQVLINLVRNGIEAMSEGGCERreLTIRTSPADDrAVTISVKDTGPGIAEevAGQLFDPFYTTKSEGLGMGLSICRSII 80
|
90 100
....*....|....*....|....
gi 648465101 545 ESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:cd16920 81 EAHGGRLSVESPAGGGATFQFTLP 104
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
211-568 |
2.68e-34 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 136.45 E-value: 2.68e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 211 MTSMTDITEPKRIREALTAAHERFMTVLESLDDTISVVADTPNGTELLFANRTYRRLWGSEAHGHTLLYNAATAHHENDP 290
Cdd:COG4251 141 ALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLS 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 291 LANNELYIAQIGAWFEVQHRTLNWTDGRKVRLQVARDISQRREYEQKLSAQQEKVQLSGRlsTLGEMASSLAHELNQPLT 370
Cdd:COG4251 221 LGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEEELEERTAELERSNE--ELEQFAYVASHDLREPLR 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 371 AIVNYnsaiAALIKSEHLDQ--ERLLQVLDKSVSQAERAGRIIGRIRDFVR--RNEPERQAVKIDTIVENTMDLafFESR 446
Cdd:COG4251 299 KISGF----SQLLEEDYGDKldEEGREYLERIRDAAERMQALIDDLLAYSRvgRQELEFEPVDLNELLEEVLED--LEPR 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 447 KYSKQIEVNLpEDLPEVYADPILIEQVLLNLVKNGIEAMSQSEHETLYVNISQVGLEIQVQVIDSGHGLkDP---ERLFE 523
Cdd:COG4251 373 IEERGAEIEV-GPLPTVRGDPTLLRQVFQNLISNAIKYSRPGEPPRIEIGAEREGGEWVFSVRDNGIGI-DPeyaEKIFE 450
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 648465101 524 PFY----STKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:COG4251 451 IFQrlhsRDEYEGTGIGLAIVKKIVERHGGRIWVESEPGEGATFYFTLP 499
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
331-568 |
4.52e-34 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 134.91 E-value: 4.52e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 331 RREYEQKLSAQQEKVQLSGRLSTLGEMASSLAHELNQPLTAIVNYNSAIAALIKSEHLDQErLLQVLdksVSQAERAGRI 410
Cdd:PRK10364 214 YRRYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQ-LAQVM---AKEADRLNRV 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 411 IGRIRDFVRRNEPERQAVKIDTIVENTMDLAFFESRKYSKQIEVNLPEDLPEVYADPILIEQVLLNLVKNGIEAMSQseH 490
Cdd:PRK10364 290 VSELLELVKPTHLALQAVDLNDLINHSLQLVSQDANSREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQ--H 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 491 ETLYVNISQVGLEIQVQVIDSGHGL--KDPERLFEPFYSTKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:PRK10364 368 GVISVTASESGAGVKISVTDSGKGIaaDQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLP 447
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
331-568 |
1.70e-32 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 130.25 E-value: 1.70e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 331 RREYEQKLSAQQEKvqlsgRLSTLGEMASSLAHELNQPLTAIVNYnsaiAALIKSEHLD--QERLLQVLDKSVSqaerag 408
Cdd:COG5808 223 KTLLERVIQEINTQ-----KLELIGTFAASTAHEIRNPLTSIKGF----IQLLQEKYPEleDQKYFDIIQEEIQ------ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 409 RIIGRIRDFVRRNEPERQAVKID---TIVENTMDLAFFESRKYSKQIEVNLPEDLPEVYADPILIEQVLLNLVKNGIEAM 485
Cdd:COG5808 288 RINQIVSEFLVLGKPTAKKLELDdlnELIEEILSIIDSEANLKNIRVEKQSLDEPLHIKCDKDRIKQVLLNLIKNAIEAM 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 486 SQSehETLYVNISQVGLEIQVQVIDSGHGL--KDPERLFEPFYSTKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIF 563
Cdd:COG5808 368 KEG--GKLTISIENDDEKAVIEVIDNGEGIpeDIIDEIFEPFVTTKEGGTGLGLSVCKRIVEMHGGEIDIESEEGKGTTF 445
|
....*
gi 648465101 564 TFRIP 568
Cdd:COG5808 446 TIRLP 450
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
94-338 |
2.77e-29 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 116.66 E-value: 2.77e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 94 EAEEQLFLETTFRRAMENSMSTGMRVLDLQGRVVYVNPAFCRMVGWNESELLGTLFPYPYWVEDKFEQHEKYLDIVLSGK 173
Cdd:COG2202 1 TAEEALEESERRLRALVESSPDAIIITDLDGRILYVNPAFERLTGYSAEELLGKTLRDLLPPEDDDEFLELLRAALAGGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 174 TPSsgMEMEAKRRDGSIFTARLYVSPLMDPNGEQIGWMTSMTDITEPKRIREALTAAHERFMTVLESLDDTISVVadTPN 253
Cdd:COG2202 81 VWR--GELRNRRKDGSLFWVELSISPVRDEDGEITGFVGIARDITERKRAEEALRESEERLRLLVENAPDGIFVL--DLD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 254 GTeLLFANRTYRRLWGSEAHGHTLLYNAATAHHENDPLANNEL----------------YIAQIGAWFEVQHRTLNWTDG 317
Cdd:COG2202 157 GR-ILYVNPAAEELLGYSPEELLGKSLLDLLHPEDRERLLELLrrlleggresyelelrLKDGDGRWVWVEASAVPLRDG 235
|
250 260
....*....|....*....|...
gi 648465101 318 RKVR--LQVARDISQRREYEQKL 338
Cdd:COG2202 236 GEVIgvLGIVRDITERKRAEEAL 258
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
335-572 |
3.32e-29 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 119.29 E-value: 3.32e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 335 EQKLSAQQEKVQLSGRLSTLGEMASSLAHELNQPLTAivnynSAIAalIKSEHLDQ-----ERLLQVLDKSVSQAERAGR 409
Cdd:PRK09303 132 DELFVLRQENETLLEQLKFKDRVLAMLAHDLRTPLTA-----ASLA--LETLELGQidedtELKPALIEQLQDQARRQLE 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 410 IIGR-IRDFVR----RNEPER-QAVKID------TIVENTMDLafFESRkySKQIEVNLPEDLPEVYADPILIEQVLLNL 477
Cdd:PRK09303 205 EIERlITDLLEvgrtRWEALRfNPQKLDlgslcqEVILELEKR--WLAK--SLEIQTDIPSDLPSVYADQERIRQVLLNL 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 478 VKNGIEamSQSEHETLYVNI----SQvglEIQVQVIDSGHG--LKDPERLFEPFY----STKKEGLGIGLNICRSIIESH 547
Cdd:PRK09303 281 LDNAIK--YTPEGGTITLSMlhrtTQ---KVQVSICDTGPGipEEEQERIFEDRVrlprDEGTEGYGIGLSVCRRIVRVH 355
|
250 260
....*....|....*....|....*
gi 648465101 548 RGRLWAENNPSGGTIFTFRIPCYRK 572
Cdd:PRK09303 356 YGQIWVDSEPGQGSCFHFTLPVYRG 380
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
333-570 |
2.02e-28 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 117.66 E-value: 2.02e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 333 EYEQKLSAQQEKVQLSGRLSTLGEMASSLAHELNQPLTAIVNYnsaiAALIKSEHLDQERLLQVLDKSVSQAERAGRIIG 412
Cdd:COG5806 180 ENLIENILLRKELQRAEKLEVVSELAASIAHEVRNPLTVVRGF----IQLLQEPELSDEKRKQYIRIALEELDRAEAIIT 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 413 RIRDFVRRNEPERQAVKIDTIVENTMDLAFFESRKYSKQIEVNLPEDLpEVYADPILIEQVLLNLVKNGIEAMSQSEheT 492
Cdd:COG5806 256 DYLTFAKPQPEKLEKIDVSEELEHVIDVLSPYANMNNVEIQTELEPGL-YIEGDRQKLQQCLINIIKNGIEAMPNGG--T 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 493 LYVNISQVGLEIQVQVIDSGHGLkDPE---RLFEPFYSTKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIPC 569
Cdd:COG5806 333 LTIDVSIDKNKVIISIKDTGVGM-TKEqleRLGEPYFSTKEKGTGLGTMVSYRIIEAMNGTIRVESEVGKGTTFTITLPL 411
|
.
gi 648465101 570 Y 570
Cdd:COG5806 412 A 412
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
465-568 |
2.38e-27 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 106.19 E-value: 2.38e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 465 ADPILIEQVLLNLVKNGIEAMSqsEHETLYVNISQVGLEIQVQVIDSGHGL--KDPERLFEPFYSTKK-----EGLGIGL 537
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTP--EGGRITVTLERDGDHVEITVEDNGPGIppEDLEKIFEPFFRTDKrsrkiGGTGLGL 78
|
90 100 110
....*....|....*....|....*....|.
gi 648465101 538 NICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:smart00387 79 SIVKKLVELHGGEISVESEPGGGTTFTITLP 109
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
188-568 |
2.95e-24 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 104.93 E-value: 2.95e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 188 GSIFTARLYVSPLMDPNGEQIGWMTSMTDITEPKRIREALTAAHERFMTVLESLDDTISVVADTPNGTellFANRTYRRL 267
Cdd:COG3290 40 LLFLLFVIILLLLLLILLLILLLLLLLLLAALLLKLLEEIARLVEEREAVLESIREGVIAVDRDGRIT---LINDAARRL 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 268 WGSEAHGHTLLYNAATAHHENDplANNELYIAqiGAWFEVQHRTLNWTDGRKVRLQVARDISQRREYEQKLSAQQEKVql 347
Cdd:COG3290 117 LGLDAIGRPIDEVLAEVLETGE--RDEEILLN--GRVLVVNRVPIRDDGRVVGAVATFRDRTELERLEEELEGVKELA-- 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 348 sgrlstlgEMASSLAHELNqpltaivNYNSAIAALIKSEHLDQerLLQVLDKSVSQAER-AGRIIGRIRDFVrrneperq 426
Cdd:COG3290 191 --------EALRAQRHDFR-------NHLHTISGLLQLGEYDE--ALEYIDEISEELQElIDSLLSRIGNPV-------- 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 427 avkIDTIVENTMDLAffesrkYSKQIEVNL--PEDLPEVYADPILIEQVLLNLVKNGIEAMSQSEHE--TLYVNISQVGL 502
Cdd:COG3290 246 ---LAALLLGKAARA------RERGIDLTIdiDSDLPDLPLSDTDLVTILGNLLDNAIEAVEKLPEEerRVELSIRDDGD 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 648465101 503 EIQVQVIDSGHGL--KDPERLFEPFYSTKK-EGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:COG3290 317 ELVIEVEDSGPGIpeELLEKIFERGFSTKLgEGRGLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRLP 385
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
465-568 |
6.36e-24 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 96.67 E-value: 6.36e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 465 ADPILIEQVLLNLVKNGIEAMSQSEHetLYVNISQVGlEIQVQVIDSGHGL--KDPERLFEPFYS---TKKEGLGIGLNI 539
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGE--ITVTLSEGG-ELTLTVEDNGIGIppEDLPRIFEPFSTadkRGGGGTGLGLSI 77
|
90 100
....*....|....*....|....*....
gi 648465101 540 CRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:pfam02518 78 VRKLVELLGGTITVESEPGGGTTVTLTLP 106
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
326-568 |
8.17e-24 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 104.93 E-value: 8.17e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 326 RDISQRREYEQKLSAQqEKVQL----SGRLSTLG-EMAS----------------SLAHELNQPLTAIVNynsaiAALIK 384
Cdd:PRK11100 208 RSIRRLTRYADAVTEG-KPVPLpklgSSELRELAqALESmrvklegkayveqyvqTLTHELKSPLAAIRG-----AAELL 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 385 SEHLDQERLLQVLDKSVSQAERAGRIIGRIRDFVR---RNEPE-RQAVKIDTIVENTMDLAffESRKYSKQIEVNLPEDL 460
Cdd:PRK11100 282 QEDPPPEDRARFTGNILTQSARLQQLIDRLLELARleqRQELEvLEPVALAALLEELVEAR--EAQAAAKGITLRLRPDD 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 461 PEVYADPILIEQVLLNLVKNGIE-AMSQSeheTLYVNISQVGLEIQVQVIDSGHGLKDP--ERLFEPFYS-----TKKEG 532
Cdd:PRK11100 360 ARVLGDPFLLRQALGNLLDNAIDfSPEGG---TITLSAEVDGEQVALSVEDQGPGIPDYalPRIFERFYSlprpaNGRKS 436
|
250 260 270
....*....|....*....|....*....|....*.
gi 648465101 533 LGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:PRK11100 437 TGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLP 472
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
451-568 |
1.47e-22 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 102.42 E-value: 1.47e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 451 QIEVNLPEDLPEVYADPILIEQVLLNLVKNGIE-AMSQSeheTLYVNISQVGLEIQVQVIDSGHGLK--DPERLFEPFYS 527
Cdd:PRK10490 760 PINLSLPEPLTLIHVDGPLFERVLINLLENAVKyAGAQA---EIGIDAHVEGERLQLDVWDNGPGIPpgQEQLIFDKFAR 836
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 648465101 528 TKKE----GLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:PRK10490 837 GNKEsaipGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVTLP 881
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
322-568 |
5.93e-22 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 100.52 E-value: 5.93e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 322 LQVARDISQRREYEQKLsaqqekvQLSGRLSTLGEMASSLAHELNQPLTAIVNYnsAIAALIKSEhlDQERLLQVLDKSV 401
Cdd:PRK13837 425 IERRRLETERDALERRL-------EHARRLEAVGTLASGIAHNFNNILGAILGY--AEMALNKLA--RHSRAARYIDEII 493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 402 SQAERAGRIIGRIRDFVRRNEPERQAVKIDTIVENTMDLaFFESRKYSKQIEVNLPEDLPEVYADPILIEQVLLNLVKNG 481
Cdd:PRK13837 494 SAGARARLIIDQILAFGRKGERNTKPFDLSELVTEIAPL-LRVSLPPGVELDFDQDQEPAVVEGNPAELQQVLMNLCSNA 572
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 482 IEAMSQSEHETLYVNISQV-------------GLEIQVQVIDSGHGLkDP---ERLFEPFYSTKKEGLGIGLNICRSIIE 545
Cdd:PRK13837 573 AQAMDGAGRVDISLSRAKLrapkvlshgvlppGRYVLLRVSDTGAGI-DEavlPHIFEPFFTTRAGGTGLGLATVHGIVS 651
|
250 260
....*....|....*....|...
gi 648465101 546 SHRGRLWAENNPSGGTIFTFRIP 568
Cdd:PRK13837 652 AHAGYIDVQSTVGRGTRFDVYLP 674
|
|
| sensory_box |
TIGR00229 |
PAS domain S-box; The PAS domain was previously described. This sensory box, or S-box domain ... |
104-227 |
8.10e-22 |
|
PAS domain S-box; The PAS domain was previously described. This sensory box, or S-box domain occupies the central portion of the PAS domain but is more widely distributed. It is often tandemly repeated. Known prosthetic groups bound in the S-box domain include heme in the oxygen sensor FixL, FAD in the redox potential sensor NifL, and a 4-hydroxycinnamyl chromophore in photoactive yellow protein. Proteins containing the domain often contain other regulatory domains such as response regulator or sensor histidine kinase domains. Other S-box proteins include phytochromes and the aryl hydrocarbon receptor nuclear translocator. [Regulatory functions, Small molecule interactions]
Pssm-ID: 272971 [Multi-domain] Cd Length: 124 Bit Score: 91.20 E-value: 8.10e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 104 TFRRAMENSMSTGMRVLDLQGRVVYVNPAFCRMVGWNESELLGTLFPYpYWVEDKFEQHEKYLDIVLSGKTPSSGMEMEA 183
Cdd:TIGR00229 3 ERYRAIFESSPDAIIVIDLEGNILYVNPAFEEIFGYSAEELIGRNVLE-LIPEEDREEVRERIERRLEGEPEPVSEERRV 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 648465101 184 KRRDGSIFTARLYVSPlMDPNGEQIGWMTSMTDITEPKRIREAL 227
Cdd:TIGR00229 82 RRKDGSEIWVEVSVSP-IRTNGGELGVVGIVRDITERKEAEEAL 124
|
|
| PEP_his_kin |
TIGR02916 |
putative PEP-CTERM system histidine kinase; Members of this protein family have a novel ... |
311-568 |
3.14e-21 |
|
putative PEP-CTERM system histidine kinase; Members of this protein family have a novel N-terminal domain, a single predicted membrane-spanning helix, and a predicted cystosolic histidine kinase domain. We designate this protein PrsK, and its companion DNA-binding response regulator protein (TIGR02915) PrsR. These predicted signal-transducing proteins appear to enable enhancer-dependent transcriptional activation. The prsK gene is often associated with exopolysaccharide biosynthesis genes. [Protein fate, Protein and peptide secretion and trafficking, Signal transduction, Two-component systems]
Pssm-ID: 274349 [Multi-domain] Cd Length: 679 Bit Score: 97.87 E-value: 3.14e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 311 TLNWTDG---RKVRLQVARDISQRREYEQKLSAQQekvqlsgrLSTLGEMASSLAHELNQPLT--AIVNYNSAiaaliks 385
Cdd:TIGR02916 437 EFNWEVRdllKTAGRQAASYLAQMEASEALAEARQ--------FEAFNRMSAFVVHDLKNLVAqlSLLLRNAE------- 501
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 386 EHLD----QERLLQVLDKSVsqaERAGRIIGRIRdfvRRNEPERQaVKIDtiVENTMDLAFFESRKYSKQIEVNLPEDLp 461
Cdd:TIGR02916 502 RHKDnpefQDDMLETVENAV---NRMKKLLAQLR---SKGLEEEK-LCVD--LVDLLRRAIASKRAQGPRPEVSIDTDL- 571
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 462 EVYADPILIEQVLLNLVKNGIEAMSQSEHETlyVNISQVGLEIQVQVIDSGHGLKDP---ERLFEPFYSTKKEGLGIGLN 538
Cdd:TIGR02916 572 SVRADRERLERVLGHLVQNALEATPGEGRVA--IRVERECGAARIEIEDSGCGMSPAfirERLFKPFDTTKGAGMGIGVY 649
|
250 260 270
....*....|....*....|....*....|
gi 648465101 539 ICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:TIGR02916 650 ECRQYVEEIGGRIEVESTPGQGTIFTLVLP 679
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
327-537 |
3.74e-19 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 90.89 E-value: 3.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 327 DISQRREYEQKLSAQQekvqlsgRLSTLGEMASSLAHELNQPLTAIVNYNSAIAALIKSEHLDQERLLQVLDKSVSQAER 406
Cdd:PRK13557 143 DVSRRRDAEDALRQAQ-------KMEALGQLTGGIAHDFNNLLQVMSGYLDVIQAALSHPDADRGRMARSVENIRAAAER 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 407 AGRIIGRIRDFVRRNEPERQAVKIDTIVENTMDLAffeSRKY--SKQIEVNLPEDLPEVYADPILIEQVLLNLVKNGIEA 484
Cdd:PRK13557 216 AATLTQQLLAFARKQRLEGRVLNLNGLVSGMGELA---ERTLgdAVTIETDLAPDLWNCRIDPTQAEVALLNVLINARDA 292
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 648465101 485 MSQSEH---ETLYVNISQV----------GLEIQVQVIDSGHGLKdPE---RLFEPFYSTKKEGLGIGL 537
Cdd:PRK13557 293 MPEGGRvtiRTRNVEIEDEdlamyhglppGRYVSIAVTDTGSGMP-PEilaRVMDPFFTTKEEGKGTGL 360
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
467-568 |
3.77e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 80.16 E-value: 3.77e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 467 PILIEQVLLNLVKNGIEAMSqsEHETLYVNISQVGLEIQVQVIDSGHGLkDPE---RLFEPFYSTK--KEGLGIGLNICR 541
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQAME--GRGRITIRTWAHVDQVLIEVEDTGSGI-DPEilgRIFDPFFTTKpvGEGTGLGLSLSY 77
|
90 100
....*....|....*....|....*..
gi 648465101 542 SIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:cd16943 78 RIIQKHGGTIRVASVPGGGTRFTIILP 104
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
470-568 |
3.92e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 80.06 E-value: 3.92e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 470 IEQVLLNLVKNGIEAMSQSEHETLYVNISQVGLEIQVQVIDSGHGLkDP---ERLFEPFY----STKKEGLGIGLNICRS 542
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRRPPRIEVGAEDVGEEWTFYVRDNGIGI-DPeyaEKVFGIFQrlhsREEYEGTGVGLAIVRK 79
|
90 100
....*....|....*....|....*.
gi 648465101 543 IIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:cd16921 80 IIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
470-569 |
8.11e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 79.07 E-value: 8.11e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 470 IEQVLLNLVKNGIEaMSQSEHETLYVN---ISQVGLEIQVQVIDSGHGLK--DPERLFEPF------YSTKKEGLGIGLN 538
Cdd:cd16922 1 LRQILLNLLGNAIK-FTEEGEVTLRVSleeEEEDGVQLRFSVEDTGIGIPeeQQARLFEPFsqadssTTRKYGGTGLGLA 79
|
90 100 110
....*....|....*....|....*....|.
gi 648465101 539 ICRSIIESHRGRLWAENNPSGGTIFTFRIPC 569
Cdd:cd16922 80 ISKKLVELMGGDISVESEPGQGSTFTFTLPL 110
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
470-565 |
1.79e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 77.88 E-value: 1.79e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 470 IEQVLLNLVKNGIEAMSQSEHETLYVNISQVGLEIQVQVIDSGHGL--KDPERLFEPFYSTKK--EGLGIGLNICRSIIE 545
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKVENPRIRIAARRLGGRLVLVVRDNGPGIaeEHLSRVFDPFFTTKPvgKGTGLGLSISYGIVE 80
|
90 100
....*....|....*....|
gi 648465101 546 SHRGRLWAENNPSGGTIFTF 565
Cdd:cd16976 81 EHGGRLSVANEEGAGARFTF 100
|
|
| PAS |
pfam00989 |
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
104-217 |
1.05e-16 |
|
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. This domain can bind gases (O2, CO and NO), FAD, 4-hydroxycinnamic acid and NAD+ (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 395786 [Multi-domain] Cd Length: 113 Bit Score: 76.30 E-value: 1.05e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 104 TFRRAMENSMSTGMRVLDLQGRVVYVNPAFCRMVGWNESELLGTLFPYPYWVEDKFEQHEKyLDIVLSGKTPSSGMEMEA 183
Cdd:pfam00989 1 EDLRAILESLPDGIFVVDEDGRILYVNAAAEELLGLSREEVIGKSLLDLIPEEDDAEVAEL-LRQALLQGEESRGFEVSF 79
|
90 100 110
....*....|....*....|....*....|....
gi 648465101 184 KRRDGSIFTARLYVSPLMDPNGEQIGWMTSMTDI 217
Cdd:pfam00989 80 RVPDGRPRHVEVRASPVRDAGGEILGFLGVLRDI 113
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
470-568 |
1.17e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 75.83 E-value: 1.17e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 470 IEQVLLNLVKNGIeamsQSEHETLYVNISQVGLEIQVQVIDSGHGLKDP--ERLFEPFY------STKKEGLGIGLNICR 541
Cdd:cd16949 1 LARALENVLRNAL----RYSPSKILLDISQDGDQWTITITDDGPGVPEDqlEQIFLPFYrvdsarDRESGGTGLGLAIAE 76
|
90 100
....*....|....*....|....*..
gi 648465101 542 SIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:cd16949 77 RAIEQHGGKIKASNRKPGGLRVRIWLP 103
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
326-568 |
1.71e-15 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 80.16 E-value: 1.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 326 RDISQRREYEQKLSAQQEKVqLSGRLSTlGEMASSLAHELNQPLTAIVNYnsaiAALIKSEHLDQERLLQVLDKSVSQAE 405
Cdd:PRK09959 686 QDITETRDLIHALEVERNKA-INATVAK-SQFLATMSHEIRTPISSIMGF----LELLSGSGLSKEQRVEAISLAYATGQ 759
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 406 RAGRIIGRIRDFVR----RNEPERQAVKIDTIVENTMDlaFFESRKYSKQIEVNLPEDLPEVY---ADPILIEQVLLNLV 478
Cdd:PRK09959 760 SLLGLIGEILDVDKiesgNYQLQPQWVDIPTLVQNTCH--SFGAIAASKSIALSCSSTFPDHYlvkIDPQAFKQVLSNLL 837
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 479 KNGIEAMSQSEHE--TLYVNISQVGLEIQVQVIDSGHGLKDPER--LFEPFYST----KKEGLGIGLNICRSIIESHRGR 550
Cdd:PRK09959 838 SNALKFTTEGAVKitTSLGHIDDNHAVIKMTIMDSGSGLSQEEQqqLFKRYSQTsagrQQTGSGLGLMICKELIKNMQGD 917
|
250
....*....|....*...
gi 648465101 551 LWAENNPSGGTIFTFRIP 568
Cdd:PRK09959 918 LSLESHPGIGTTFTITIP 935
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
470-568 |
1.83e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 72.43 E-value: 1.83e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 470 IEQVLLNLVKNGIEAMSQSEHETL-------YVNISQVG--LEIQVQVIDSGHGLKDP--ERLFEPFYSTKKEGLGIGLN 538
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSGGEIIlrtrtqrQVTLGHPRhrLALRVSVIDNGPGIPPDlqDTIFYPMVSGRENGTGLGLA 80
|
90 100 110
....*....|....*....|....*....|
gi 648465101 539 ICRSIIESHRGRLWAENNPsGGTIFTFRIP 568
Cdd:cd16918 81 IAQNIVSQHGGVIECDSQP-GHTVFSVSLP 109
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
466-568 |
2.73e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 71.80 E-value: 2.73e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 466 DPILIEQVLLNLVKNGIEAMSQSE----HETLYVNISQVGlEIQVQVIDSGHGLKDPE--RLFEPFYSTKKEGLGIGLNI 539
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEGRPsdvgEVRIRVEADQDG-RIVLIVCDNGKGFPREMrhRATEPYVTTRPKGTGLGLAI 79
|
90 100
....*....|....*....|....*....
gi 648465101 540 CRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:cd16944 80 VKKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
326-568 |
2.30e-14 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 74.73 E-value: 2.30e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 326 RDISQRREYEQKLsaQQEKVQLSGRlstlgEMASSLAHELNQPLTAIVNynsaiAALIKSEHLDQERLLQVLDKSVSQAE 405
Cdd:PRK11073 109 APMDNQRRLSQEQ--LQHAQQVAAR-----DLVRGLAHEIKNPLGGLRG-----AAQLLSKALPDPALTEYTKVIIEQAD 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 406 RagriigrIRDFVRR----NEP-ERQAVKIDTIVENTMDLAFFESrKYSKQIEVNLPEDLPEVYADPILIEQVLLNLVKN 480
Cdd:PRK11073 177 R-------LRNLVDRllgpQRPgTHVTESIHKVAERVVQLVSLEL-PDNVRLIRDYDPSLPELAHDPDQIEQVLLNIVRN 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 481 GIEAMSQsEHETLYV---NISQVGLEIQ-------VQVIDSGHGLKD--PERLFEPFYSTKKEGLGIGLNICRSIIESHR 548
Cdd:PRK11073 249 ALQALGP-EGGTITLrtrTAFQLTLHGEryrlaarIDIEDNGPGIPPhlQDTLFYPMVSGREGGTGLGLSIARNLIDQHS 327
|
250 260
....*....|....*....|
gi 648465101 549 GRLWAENNPsGGTIFTFRIP 568
Cdd:PRK11073 328 GKIEFTSWP-GHTEFSVYLP 346
|
|
| PRK09776 |
PRK09776 |
putative diguanylate cyclase; Provisional |
102-233 |
3.86e-14 |
|
putative diguanylate cyclase; Provisional
Pssm-ID: 182070 [Multi-domain] Cd Length: 1092 Bit Score: 75.86 E-value: 3.86e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 102 ETTFRRAMENSmSTGMRVLDLQGRVVYVNPAFCRMVGWNESELLGTLFPYPYWVEDkFEQHEKYLDIVLSGKTPSSGMEM 181
Cdd:PRK09776 282 ETRFRNAMEYS-AIGMALVGTEGQWLQVNKALCQFLGYSQEELRGLTFQQLTWPED-LNKDLQQVEKLLSGEINSYSMEK 359
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 648465101 182 EAKRRDGSIFTARLYVSPLMDPNGEQIGWMTSMTDITEPKRIREALTAAHER 233
Cdd:PRK09776 360 RYYRRDGEVVWALLAVSLVRDTDGTPLYFIAQIEDINELKRTEQVNERLMER 411
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
466-568 |
1.25e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 67.10 E-value: 1.25e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 466 DPILIEQVLLNLVKNGIEamSQSEHETLYVNISQVGLEIQVQVIDSGHGLKDPE--RLFEPFYSTKKE------GLGIGL 537
Cdd:cd16946 1 DRDRLQQLFVNLLENSLR--YTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQlaRLFERFYRVESSrnrasgGSGLGL 78
|
90 100 110
....*....|....*....|....*....|.
gi 648465101 538 NICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:cd16946 79 AICHNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
476-568 |
1.32e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 66.93 E-value: 1.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 476 NLVKNGIEAM--SQSEHETLYVNISQVGLEIQVQVIDSGHGL--KDPERLFEPFYSTKKEG-LGIGLNICRSIIESHRGR 550
Cdd:cd16915 7 NLIDNALDALaaTGAPNKQVEVFLRDEGDDLVIEVRDTGPGIapELRDKVFERGVSTKGQGeRGIGLALVRQSVERLGGS 86
|
90
....*....|....*...
gi 648465101 551 LWAENNPSGGTIFTFRIP 568
Cdd:cd16915 87 ITVESEPGGGTTFSIRIP 104
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
361-568 |
1.47e-13 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 73.27 E-value: 1.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 361 LAHELNQPLTAIVNyNSAIAAlikSEHLDQERLLQVLDKSVSQAERAGRIIGRIRDFVRRNE----PERQAVKIDTIVEN 436
Cdd:PRK09835 269 IAHEIRTPITNLIT-QTEIAL---SQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNnqliPEKKMLDLADEVGK 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 437 TMDlaFFESRKYSKQIEVNLPEDLPEVYADPILIEQVLLNLVKNGIEamSQSEHETLYVNISQVglEIQVQVIDSGHGLK 516
Cdd:PRK09835 345 VFD--FFEAWAEERGVELRFVGDPCQVAGDPLMLRRAISNLLSNALR--YTPAGEAITVRCQEV--DHQVQLVVENPGTP 418
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 648465101 517 DPE----RLFEPFYST------KKEGLGIGLNICRSIIESHRGRLWAENNPSgGTIFTFRIP 568
Cdd:PRK09835 419 IAPehlpRLFDRFYRVdpsrqrKGEGSGIGLAIVKSIVVAHKGTVAVTSDAR-GTRFVISLP 479
|
|
| PAS_4 |
pfam08448 |
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
119-222 |
1.95e-13 |
|
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. This domain is associated to signalling systems and works as a signal sensor domain. It recognizes differently substituted aromatic hydrocarbons, oxygen, different dodecanoic acids, autoinducers, 3,5-dimethyl-pyrazin-2-ol and N-alanyl-aminoacetone (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 312075 [Multi-domain] Cd Length: 110 Bit Score: 66.67 E-value: 1.95e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 119 VLDLQGRVVYVNPAFCRMVGWNESELLGtLFPYPYWVEDKFEQHEKYLDIVLSGKTPSSGmeMEAKRRDGSIFTARLYVS 198
Cdd:pfam08448 10 VLDPDGRVRYANAAAAELFGLPPEELLG-KTLAELLPPEDAARLERALRRALEGEEPIDF--LEELLLNGEERHYELRLT 86
|
90 100
....*....|....*....|....
gi 648465101 199 PLMDPNGEQIGWMTSMTDITEPKR 222
Cdd:pfam08448 87 PLRDPDGEVIGVLVISRDITERRR 110
|
|
| PAS |
cd00130 |
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
113-217 |
2.36e-13 |
|
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction.
Pssm-ID: 238075 [Multi-domain] Cd Length: 103 Bit Score: 66.12 E-value: 2.36e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 113 MSTGMRVLDLQGRVVYVNPAFCRMVGWNESELLGTLFpYPYWVEDKFEQHEKYLDIVLSGKTPSSGmEMEAKRRDGSIFT 192
Cdd:cd00130 1 LPDGVIVLDLDGRILYANPAAEQLLGYSPEELIGKSL-LDLIHPEDREELRERLENLLSGGEPVTL-EVRLRRKDGSVIW 78
|
90 100
....*....|....*....|....*
gi 648465101 193 ARLYVSPLMDPNGEQIGWMTSMTDI 217
Cdd:cd00130 79 VLVSLTPIRDEGGEVIGLLGVVRDI 103
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
335-570 |
7.11e-13 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 70.73 E-value: 7.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 335 EQKLSAQQekvqlsgRLstlgemASSLAHELNQPLTAIvnynsAIA-ALIKSEHLD-QErlLQVLDksvSQAERAGRIIG 412
Cdd:PRK09470 237 ERMMTSQQ-------RL------LSDISHELRTPLTRL-----QLAtALLRRRQGEsKE--LERIE---TEAQRLDSMIN 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 413 RIRDFVR---RNEPERQAVKIDTIVENTMDLAFFESRKYSKQIEVNLPEDLPEVYADPILIEQVLLNLVKNGIeamsQSE 489
Cdd:PRK09470 294 DLLVLSRnqqKNHLERETFKANSLWSEVLEDAKFEAEQMGKSLTVSAPPGPWPINGNPNALASALENIVRNAL----RYS 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 490 HETLYVNISQVGLEIQVQVIDSGHGLKDPER--LFEPFYST------KKEGLGIGLNICRSIIESHRGRLWAENNPSGGT 561
Cdd:PRK09470 370 HTKIEVAFSVDKDGLTITVDDDGPGVPEEEReqIFRPFYRVdeardrESGGTGLGLAIVENAIQQHRGWVKAEDSPLGGL 449
|
....*....
gi 648465101 562 IFTFRIPCY 570
Cdd:PRK09470 450 RLTIWLPLY 458
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
410-568 |
1.82e-12 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 69.55 E-value: 1.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 410 IIGRIRDFVRR-NEPERQAVKIDTIVEntmDLAFFESrKYSKQIEVNLPEDLPEVYADPILIEQVLLNLVKNG------- 481
Cdd:PRK09467 275 IIEQFIDYLRTgQEMPMEMADLNALLG---EVIAAES-GYEREIETALQPGPIEVPMNPIAIKRALANLVVNAarygngw 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 482 IEAMSQSEHETLYvnisqvgleiqVQVIDSGHGLK--DPERLFEPFYSTKK----EGLGIGLNICRSIIESHRGRLWAEN 555
Cdd:PRK09467 351 IKVSSGTEGKRAW-----------FQVEDDGPGIPpeQLKHLFQPFTRGDSargsSGTGLGLAIVKRIVDQHNGKVELGN 419
|
170
....*....|...
gi 648465101 556 NPSGGTIFTFRIP 568
Cdd:PRK09467 420 SEEGGLSARAWLP 432
|
|
| PAS_9 |
pfam13426 |
PAS domain; This domain is found in many signalling proteins in which it functions as a sensor ... |
123-219 |
1.41e-11 |
|
PAS domain; This domain is found in many signalling proteins in which it functions as a sensor domain. It recognizes FMN, Zn(II), FAD and riboflavin (MAtilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 463873 [Multi-domain] Cd Length: 93 Bit Score: 60.94 E-value: 1.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 123 QGRVVYVNPAFCRMVGWNESELLGTlfpYPYWVEDKFEQHEKYLDIVLSGKTPSSGmEMEAKRRDGSIFTARLYVSPLMD 202
Cdd:pfam13426 1 DGRIIYVNDAALRLLGYTREELLGK---SITDLFAEPEDSERLREALREGKAVREF-EVVLYRKDGEPFPVLVSLAPIRD 76
|
90
....*....|....*..
gi 648465101 203 PNGEQIGWMTSMTDITE 219
Cdd:pfam13426 77 DGGELVGIIAILRDITE 93
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
441-574 |
1.45e-11 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 66.97 E-value: 1.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 441 AFFESRKYSKQIEVNLpeDLPE---VYADPILIEQVLLNLVKN---------GIEAMSQSEHETLYVNISqvgleiqvqv 508
Cdd:PRK10549 323 GAFRERFASRGLTLQL--SLPDsatVFGDPDRLMQLFNNLLENslrytdsggSLHISAEQRDKTLRLTFA---------- 390
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 648465101 509 iDSGHGLKDP--ERLFEPFYSTKKE------GLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIPCYRKAD 574
Cdd:PRK10549 391 -DSAPGVSDEqlQKLFERFYRTEGSrnrasgGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQ 463
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
466-560 |
4.36e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 59.78 E-value: 4.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 466 DPILIEQVLLNLVKNGIEAMSQSEHETLYVNISQVGleIQVQVIDSGHGLKD--PERLFEPFYS-----TKKEGLGIGLN 538
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEG--IELLVFDEGSGIPDyaLNRVFERFYSlprphSGQKSTGLGLA 78
|
90 100
....*....|....*....|..
gi 648465101 539 ICRSIIESHRGRLWAENNPSGG 560
Cdd:cd16945 79 FVQEVAQLHGGRITLRNRPDGV 100
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
450-568 |
5.40e-10 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 61.54 E-value: 5.40e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 450 KQIEVNLPEDLPEVYADPILIEQVLLNLVKNGIEAMSQSEHETLYVNISQVGLeiqvQVIDSGHG--LKDPERLFEPFY- 526
Cdd:PRK10604 300 KTVRLDTPHQGDYGALDMRLMERVLDNLLNNALRYAHSRVRVSLLLDGNQACL----IVEDDGPGipPEERERVFEPFVr 375
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 648465101 527 -----STKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:PRK10604 376 ldpsrDRATGGCGLGLAIVHSIALAMGGSVNCDESELGGARFSFSWP 422
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
327-571 |
7.49e-10 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 61.91 E-value: 7.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 327 DISQRREYEQKLsaqQEKVQLSGRLSTLGEM-ASSLAHELNQPLTAIV-NYNsaiaaLIKSEHLDQE--RLLQVLDKSVS 402
Cdd:PRK10841 422 DVSARVKMEESL---QEMAQAAEQASQSKSMfLATVSHELRTPLYGIIgNLD-----LLQTKELPKGvdRLVTAMNNSSS 493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 403 QAERagrIIGRIRDFVR------RNEPERQAVK--IDTIVENTMDLAFfesrkySKQ------IEVNLPEDLpevYADPI 468
Cdd:PRK10841 494 LLLK---IISDILDFSKieseqlKIEPREFSPRevINHITANYLPLVV------KKRlglycfIEPDVPVAL---NGDPM 561
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 469 LIEQVLLNLVKNGIEaMSQSEHETLYVNISQVGLEIQVQviDSGHGLKDPE--RLFEPFY--STKKE----GLGIGLNIC 540
Cdd:PRK10841 562 RLQQVISNLLSNAIK-FTDTGCIVLHVRVDGDYLSFRVR--DTGVGIPAKEvvRLFDPFFqvGTGVQrnfqGTGLGLAIC 638
|
250 260 270
....*....|....*....|....*....|.
gi 648465101 541 RSIIESHRGRLWAENNPSGGTIFTFRIPCYR 571
Cdd:PRK10841 639 EKLINMMDGDISVDSEPGMGSQFTIRIPLYG 669
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
466-568 |
1.39e-09 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 55.58 E-value: 1.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 466 DPILIEQVLLNLVKNGIEAMSQSEHETLYVNISQVGlEIQVQVIDSGHGLKDP--ERLFEPFY------STKKEGLGIGL 537
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRIRCILEKFRLN-RFLLTVSDSGPGIPPNlrEEIFERFRqgdgssTRAHGGTGLGL 79
|
90 100 110
....*....|....*....|....*....|.
gi 648465101 538 NICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:cd16925 80 SIVKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| PRK13560 |
PRK13560 |
hypothetical protein; Provisional |
92-231 |
1.41e-09 |
|
hypothetical protein; Provisional
Pssm-ID: 106506 [Multi-domain] Cd Length: 807 Bit Score: 60.84 E-value: 1.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 92 RSEAEEQLFLETTFRRAMENSMSTGMRVLDLQGRVVYV-NPAFCRMVGWNESELLGTLFP--------------YPYWVE 156
Cdd:PRK13560 320 RRAAERELLEKEDMLRAIIEAAPIAAIGLDADGNICFVnNNAAERMLGWSAAEVMGKPLPgmdpelneefwcgdFQEWYP 399
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 648465101 157 D--KFEQHEKYLDIVLSGKTPSSGMEMEAKRRDGSIFTARLYVSPLMDPNGEQIGWMTSMTDITEPKRIREALTAAH 231
Cdd:PRK13560 400 DgrPMAFDACPMAKTIKGGKIFDGQEVLIEREDDGPADCSAYAEPLHDADGNIIGAIALLVDITERKQVEEQLLLAN 476
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
473-575 |
3.30e-09 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 59.54 E-value: 3.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 473 VLLNLVKNGIEAMSQSEHETLYVNISQVGLEIQVQVIDSGHGLkDPERL---FEPFYSTKKEGLGIGLNICRSIIESHRG 549
Cdd:PRK11086 437 ILGNLIENALEAVGGEEGGEISVSLHYRNGWLHCEVSDDGPGI-APDEIdaiFDKGYSTKGSNRGVGLYLVKQSVENLGG 515
|
90 100
....*....|....*....|....*.
gi 648465101 550 RLWAENNPSGGTIFTFRIPCYRKADN 575
Cdd:PRK11086 516 SIAVESEPGVGTQFFVQIPWDGERSN 541
|
|
| RocR |
COG3829 |
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis ... |
90-245 |
3.50e-09 |
|
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];
Pssm-ID: 443041 [Multi-domain] Cd Length: 448 Bit Score: 59.01 E-value: 3.50e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 90 RIRSEAEEQLFLETTFrrameNSMSTGMRVLDLQGRVVYVNPAFCRMVGWNESELLGTLfpypywVEDKFeqHEKYLDIV 169
Cdd:COG3829 2 EELELKELEEELEAIL-----DSLDDGIIVVDADGRITYVNRAAERILGLPREEVIGKN------VTELI--PNSPLLEV 68
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 648465101 170 LSGKTPSSGMEMEAKRRDGSIFTARlyvSPLMDpNGEQIGWMTSMTDITEPKRIREALTAAH-ERFMTVLESLDDTI 245
Cdd:COG3829 69 LKTGKPVTGVIQKTGGKGKTVIVTA---IPIFE-DGEVIGAVETFRDITELKRLERKLREEElERGLSAKYTFDDII 141
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
351-419 |
6.16e-09 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 52.60 E-value: 6.16e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 648465101 351 LSTLGEMASSLAHELNQPLTAIVNYnsaiAALIKSEHLDQERLLQVLDKSVSQAERAGRIIGRIRDFVR 419
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGA----LELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
354-423 |
9.36e-09 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 51.83 E-value: 9.36e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 354 LGEMASSLAHELNQPLTAIVNYnsaiAALIKSEHLDqERLLQVLDKSVSQAERAGRIIGRIRDFVRRNEP 423
Cdd:pfam00512 2 KSEFLANLSHELRTPLTAIRGY----LELLRDEKLD-EEQREYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
303-568 |
1.06e-08 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 58.03 E-value: 1.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 303 AWFEVqhRTLNWTDGRKVRLQV---ARDISQRREYEQKL-SAQQEKvqlsgrlstlGEMASSLAHELNQPLTAIVnynsA 378
Cdd:PRK11091 240 ACFEL--RKVPFYDRVGKRHGLmgfGRDITERKRYQDALeKASRDK----------TTFISTISHELRTPLNGIV----G 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 379 IAALIKSEHLDQERLLQVLDKSVSqAERAGRIIGRIRDFvrrNEPERQAVKIDTiveNTMDLAFFESRKYS--------K 450
Cdd:PRK11091 304 LSRILLDTELTAEQRKYLKTIHVS-AITLGNIFNDIIDM---DKMERRKLQLDN---QPIDFTDFLADLENlsglqaeqK 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 451 QIEVNLP--EDLPE-VYADPILIEQVLLNLVKNGIEaMSQSEHETLYVnISQVGLEIQVQVIDSGHGLKDPE--RLFEPF 525
Cdd:PRK11091 377 GLRFDLEplLPLPHkVITDGTRLRQILWNLISNAVK-FTQQGGVTVRV-RYEEGDMLTFEVEDSGIGIPEDEldKIFAMY 454
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 648465101 526 YSTKKE-------GLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:PRK11091 455 YQVKDShggkpatGTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIH 504
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
470-568 |
1.55e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 52.43 E-value: 1.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 470 IEQVLLNLVKNGIeamsQSEHETLYVNISQVGLEIQVQVIDSGHGL--KDPERLFEPF------YSTKKEGLGIGLNICR 541
Cdd:cd16939 1 MARALDNLLRNAL----RYAHRTVRIALLVSGGRLTLIVEDDGPGIpaAARERVFEPFvrldpsRDRATGGFGLGLAIVH 76
|
90 100
....*....|....*....|....*..
gi 648465101 542 SIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:cd16939 77 RVALWHGGHVECDDSELGGACFRLTWP 103
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
445-568 |
5.11e-08 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 52.97 E-value: 5.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 445 SRKYSKQIEVNLPEDLPEVyaDPILIEQV---LLNLVKN----GIE------AMSQSEHETLYVNISQVGLEIQVQVIDS 511
Cdd:cd16916 13 ARELGKQVELVVEGEDTEL--DKSVLEKLadpLTHLLRNavdhGIEapeerlAAGKPPEGTITLRAEHQGNQVVIEVSDD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 512 GHGLkDPER---------------------------LFEPFYSTKKE-----GLGIGLNICRSIIESHRGRLWAENNPSG 559
Cdd:cd16916 91 GRGI-DREKirekaierglitadeaatlsddevlnlIFAPGFSTAEQvtdvsGRGVGMDVVKRSIESLGGTIEVESEPGQ 169
|
....*....
gi 648465101 560 GTIFTFRIP 568
Cdd:cd16916 170 GTTFTIRLP 178
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
476-568 |
7.21e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 50.66 E-value: 7.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 476 NLVKNGIEAMSQSEHETLYVNISQVGLEIQVQviDSGHGLkDPE---RLFEPFYSTKKE------GLGIGLNICRSIIES 546
Cdd:cd16952 7 NLVSNAVKYTPPSDTITVRWSQEESGARLSVE--DTGPGI-PPEhipRLTERFYRVDIErcrntgGTGLGLAIVKHVMSR 83
|
90 100
....*....|....*....|..
gi 648465101 547 HRGRLWAENNPSGGTIFTFRIP 568
Cdd:cd16952 84 HDARLLIASELGKGSRFTCLFP 105
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
451-569 |
8.84e-08 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 54.64 E-value: 8.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 451 QIEVNLPEDLPEVYaDPILIEQVLL-NLVKNGIEAMSqsEHETLYVNISQVGLEIQVQVIDSGHGLkDPERLFEPF--YS 527
Cdd:COG2972 322 EVEIEIDEELLDLL-IPKLILQPLVeNAIEHGIEPKE--GGGTIRISIRKEGDRLVITVEDNGVGM-PEEKLEKLLeeLS 397
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 648465101 528 TKKEGLGIGLNICRSIIESHRG---RLWAENNPSGGTIFTFRIPC 569
Cdd:COG2972 398 SKGEGRGIGLRNVRERLKLYYGeeyGLEIESEPGEGTTVTIRIPL 442
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
473-568 |
1.03e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 50.08 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 473 VLLNLVKNgieAMSQSEHET-LYVNISQVGLEIQVQVIDSGHGLKD--PERLFEPFY----STKKEGLGIGLNICRSIIE 545
Cdd:cd16923 4 VFSNLLSN---AIKYSPENTrIYITSFLTDDVVNIMFKNPSSHPLDfkLEKLFERFYrgdnSRNTEGAGLGLSIAKAIIE 80
|
90 100
....*....|....*....|...
gi 648465101 546 SHRGRLWAENNpSGGTIFTFRIP 568
Cdd:cd16923 81 LHGGSASAEYD-DNHDLFKVRLP 102
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
472-568 |
1.10e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 50.26 E-value: 1.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 472 QVLLNLVKNgieAMSQSEHETLYVNIS--QVGLEIQVQVIDSGHGL--KDPERLFEPFYSTKKEGL------GIGLNICR 541
Cdd:cd16953 3 QVLRNLIGN---AISFSPPDTGRITVSamPTGKMVTISVEDEGPGIpqEKLESIFDRFYTERPANEafgqhsGLGLSISR 79
|
90 100 110
....*....|....*....|....*....|.
gi 648465101 542 SIIESHRGRLWAEN-NPSG---GTIFTFRIP 568
Cdd:cd16953 80 QIIEAHGGISVAENhNQPGqviGARFTVQLP 110
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
354-423 |
1.21e-07 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 48.72 E-value: 1.21e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 354 LGEMASSLAHELNQPLTAIVNYnsaiAALIKSEHLDQERlLQVLDKSVSQAERAGRIIGRIRDFVRRNEP 423
Cdd:smart00388 2 KREFLANLSHELRTPLTAIRGY----LELLLDTELSEEQ-REYLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
433-573 |
2.07e-07 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 54.14 E-value: 2.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 433 IVENTMDLAFFESRKYSKQIEVNLPEDLPE-VYADPILIEQVLLNLVKNgieAMSQSEHETLYVNISQVGLEIQVQVIDS 511
Cdd:PRK11466 524 LLESTLQLMSGRVKGRPIRLATDIADDLPTaLMGDPRRIRQVITNLLSN---ALRFTDEGSIVLRSRTDGEQWLVEVEDS 600
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 648465101 512 GHGLkDPERL---FEPFY--STKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIPCYRKA 573
Cdd:PRK11466 601 GCGI-DPAKLaeiFQPFVqvSGKRGGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRVAT 666
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
340-568 |
4.42e-07 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 53.11 E-value: 4.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 340 AQQEKVQLSGRLStlgEMASSLAHELNQPLtaivnyNSAIAA--LIKSEHLDQERLlQVLDKSVSQAERAGRIIGRIRDF 417
Cdd:PRK15347 387 AKQRAEQANKRKS---EHLTTISHEIRTPL------NGVLGAleLLQNTPLTAEQM-DLADTARQCTLSLLAIINNLLDF 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 418 VR----RNEPERQAVKIDTIVENTMdlAFFESRKYSKQI--EVNLPEDLPEV-YADPILIEQVLLNLVKNGIEaMSQSEH 490
Cdd:PRK15347 457 SRiesgQMTLSLEETALLPLLDQAM--LTIQGPAQSKSLtlRTFVGAHVPLYlHLDSLRLRQILVNLLGNAVK-FTETGG 533
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 491 ETLYVNISQVGLEIQVQviDSGHGL--KDPERLFEPFY--STKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFR 566
Cdd:PRK15347 534 IRLRVKRHEQQLCFTVE--DTGCGIdiQQQQQIFTPFYqaDTHSQGTGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLV 611
|
..
gi 648465101 567 IP 568
Cdd:PRK15347 612 LP 613
|
|
| PAS |
smart00091 |
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
105-171 |
5.63e-07 |
|
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels.
Pssm-ID: 214512 Cd Length: 67 Bit Score: 47.01 E-value: 5.63e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 648465101 105 FRRAMENSMSTGMRVLDLQGRVVYVNPAFCRMVGWNESELLGTLFpYPYWVEDKFEQHEKYLDIVLS 171
Cdd:smart00091 2 RLRAILESLPDGIFVLDLDGRILYANPAAEELLGYSPEELIGKSL-LELIHPEDRERVQEALQRLLS 67
|
|
| PRK13558 |
PRK13558 |
bacterio-opsin activator; Provisional |
126-251 |
8.56e-07 |
|
bacterio-opsin activator; Provisional
Pssm-ID: 237426 [Multi-domain] Cd Length: 665 Bit Score: 51.76 E-value: 8.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 126 VVYVNPAFCRMVGWNESELLGTlfpypywvEDKFEQHEKY-------LDIVLSGKTPSSgMEMEAKRRDGSIFTARLYVS 198
Cdd:PRK13558 173 LIYINDAFERITGYSPDEVLGR--------NCRFLQGEDTneervaeLREAIDEERPTS-VELRNYRKDGSTFWNQVDIA 243
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 648465101 199 PLMDPNGEQIGWMTSMTDITEPKRIREALTAAHERFMTVLESLDDTISVVADT 251
Cdd:PRK13558 244 PIRDEDGTVTHYVGFQTDVTERKEAELALQRERRKLQRLLERVEGLVNDVTSA 296
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
324-569 |
8.65e-07 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 50.39 E-value: 8.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 324 VARDISQRREYEQKLSAQQEKVQLSGRLSTLGEMASSLaH-ELNQPLTAIVNYnsaIAALIKSEHLDQERLLQVLDKSVS 402
Cdd:COG4585 24 LVLLRARRAERAAELERELAARAEEAREEERRRIAREL-HdGVGQSLSAIKLQ---LEAARRLLDADPEAAREELEEIRE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 403 QAERAgriIGRIRDFVRR-NEPERQAVKIDTIVENTMDLAffeSRKYSKQIEVNLPEDLPEVyadPILIEQVLLNLVKng 481
Cdd:COG4585 100 LAREA---LAELRRLVRGlRPPALDDLGLAAALEELAERL---LRAAGIRVELDVDGDPDRL---PPEVELALYRIVQ-- 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 482 iEAMS----QSEHETLYVNISQVGLEIQVQVIDSGHGLkDPERlfepfysTKKEGLGIgLNIcRSIIESHRGRLWAENNP 557
Cdd:COG4585 169 -EALTnalkHAGATRVTVTLEVDDGELTLTVRDDGVGF-DPEA-------APGGGLGL-RGM-RERAEALGGTLTIGSAP 237
|
250
....*....|..
gi 648465101 558 SGGTIFTFRIPC 569
Cdd:COG4585 238 GGGTRVRATLPL 249
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
346-568 |
1.05e-06 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 51.12 E-value: 1.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 346 QLSGRLSTLGE----MASSLAHELNQPLTAIvnyNSAIAALIKSEHLDQERLLQVLD---KSVSQ---AERAGRiigrir 415
Cdd:PRK10755 125 QLVSRLTSTLDqerlFTADVAHELRTPLAGI---RLHLELLEKQHHIDVAPLIARLDqmmHTVEQllqLARAGQ------ 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 416 DFVRRNEperQAVKI--DTIVENTMDLA-FFESRKysKQIEVNLPEDLPEVYADPILIEQVLLNLVKNgieAMSQS-EHE 491
Cdd:PRK10755 196 SFSSGHY---QTVKLleDVILPSQDELSeMLEQRQ--QTLLLPESAADITVQGDATLLRLLLRNLVEN---AHRYSpEGS 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 492 TLYVNISQVGLEIQVQVIDSGHGLKDPER--LFEPF--YSTKKEGLGIGLNICRSIIESHRGRLWAENNP-SGGTIFTFR 566
Cdd:PRK10755 268 TITIKLSQEDGGAVLAVEDEGPGIDESKCgeLSKAFvrMDSRYGGIGLGLSIVSRITQLHHGQFFLQNRQeRSGTRAWVW 347
|
..
gi 648465101 567 IP 568
Cdd:PRK10755 348 LP 349
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
466-567 |
1.81e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 46.69 E-value: 1.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 466 DPILIEQVLLNLVKNGIeamsQSEHETLYVNISqVGLE---IQVQVIDSGHGL--KDPERLFEPFYS-----TKKEGLGI 535
Cdd:cd16975 1 DTLLLSRALINIISNAC----QYAPEGGTVSIS-IYDEeeyLYFEIWDNGHGFseQDLKKALELFYRddtsrRSGGHYGM 75
|
90 100 110
....*....|....*....|....*....|..
gi 648465101 536 GLNICRSIIESHRGRLWAENNPSGGTIFTFRI 567
Cdd:cd16975 76 GLYIAKNLVEKHGGSLIIENSQKGGAEVTVKI 107
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
450-569 |
1.87e-06 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 51.00 E-value: 1.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 450 KQIE--VNLPEDLPE-VYADPILIEQVLLNLVKNGIEAMSQ------SEHETlyvnISQVGLEIQVQVIDSGHGL--KDP 518
Cdd:PRK11107 386 KGLEltLNIDPDVPDnVIGDPLRLQQIITNLVGNAIKFTESgnidilVELRA----LSNTKVQLEVQIRDTGIGIseRQQ 461
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 648465101 519 ERLFEPF------YSTKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIPC 569
Cdd:PRK11107 462 SQLFQAFrqadasISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHLPL 518
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
470-560 |
3.78e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 45.52 E-value: 3.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 470 IEQVLLNLVKNGIEamsqseHETLYVNISQ--VGLEIQVQVIDSGHGLkDPE---RLFEPFYSTKK----EGLGIGLNIC 540
Cdd:cd16950 1 LKRVLSNLVDNALR------YGGGWVEVSSdgEGNRTRIQVLDNGPGI-APEevdELFQPFYRGDNargtSGTGLGLAIV 73
|
90 100
....*....|....*....|
gi 648465101 541 RSIIESHRGRLWAENNPSGG 560
Cdd:cd16950 74 QRISDAHGGSLTLANRAGGG 93
|
|
| PAS_8 |
pfam13188 |
PAS domain; PAS domains are involved in many signalling proteins where they are used as a ... |
105-150 |
6.30e-06 |
|
PAS domain; PAS domains are involved in many signalling proteins where they are used as a signal sensor domain. PAS domains appear in archaea, bacteria and eukaryotes. Several PAS-domain proteins are known to detect their signal by way of an associated cofactor. Heme, flavin, and a 4-hydroxycinnamyl chromophore are used in different proteins. This domain recognizes oxygen and CO (Matilla et al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 463802 [Multi-domain] Cd Length: 65 Bit Score: 44.08 E-value: 6.30e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 648465101 105 FRRAMENsMSTGMRVLDLQGRVVYVNPAFCRMVGWN-ESELLGTLFP 150
Cdd:pfam13188 3 LRALFES-SPDGILVLDEGGRIIYVNPAALELLGYElLGELLGELLD 48
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
451-564 |
6.82e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 45.58 E-value: 6.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 451 QIEVNLPEDLPEVYADPILIEQVLLNLVKNGIE--------AMSQSEHETlyvnisqvglEIQVQVIDSGHGLK--DPER 520
Cdd:cd16947 2 QVEINIPDRPIYANANTEALQRILKNLISNAIKygsdgkflGMTLREDEK----------HVYIDIWDKGKGISetEKDH 71
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 648465101 521 LFEPFYS------TKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFT 564
Cdd:cd16947 72 VFERLYTledsrnSAKQGNGLGLTITKRLAESMGGSIYVNSKPYEKTVFT 121
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
471-568 |
9.48e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 45.06 E-value: 9.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 471 EQVLLNLVKNGIEAMSQSEHETLYVNISQV-------------GLEIQVQVIDSGHGLkDPE---RLFEPFYSTKKE--G 532
Cdd:cd16919 2 ELAILNLAVNARDAMPEGGRLTIETSNQRVdadyalnyrdlipGNYVCLEVSDTGSGM-PAEvlrRAFEPFFTTKEVgkG 80
|
90 100 110
....*....|....*....|....*....|....*.
gi 648465101 533 LGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:cd16919 81 TGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
385-568 |
1.36e-05 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 47.87 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 385 SEHLDQERLLQvLDKSVSQAERagrIIGRIRDFVRRnepeRQAVKIDTIVE--NTM--DLAffesRKYSKQIEVNLP-ED 459
Cdd:COG0643 200 AEELEDESLRE-LEEALEQLSR---LTRELQDGVMR----LRMVPISTVFNrfPRMvrDLA----RELGKEVELVIEgEE 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 460 LpEVyaDPILIEQV---LLNLVKN----GIE------AMSQSEHETLYVNISQVGLEIQVQVIDSGHGLkDPERL----- 521
Cdd:COG0643 268 T-EL--DRTVLERLgdpLVHLVRNavdhGIEtpeerlAAGKPETGTITLSAYHEGGRVVIEVSDDGRGL-DLEKIrakai 343
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 648465101 522 ----------------------FEPFYSTKKE-----GLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:COG0643 344 ekglitaeeaaalsdeelleliFAPGFSTAEEvtdlsGRGVGMDVVKTNIEALGGTIEIESEPGKGTTFTLRLP 417
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
468-568 |
2.95e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 43.43 E-value: 2.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 468 ILIEQVLLNLVK-----NGIEamsqsehetlyVNISQVGLEIQVQVIDSGHGL--KDPERLFEPFYSTK-----KEGLGI 535
Cdd:cd16948 8 FIIGQIVSNALKyskqgGKIE-----------IYSETNEQGVVLSIKDFGIGIpeEDLPRVFDKGFTGEngrnfQESTGM 76
|
90 100 110
....*....|....*....|....*....|...
gi 648465101 536 GLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:cd16948 77 GLYLVKKLCDKLGHKIDVESEVGEGTTFTITFP 109
|
|
| PRK11359 |
PRK11359 |
cyclic-di-GMP phosphodiesterase; Provisional |
119-225 |
4.74e-05 |
|
cyclic-di-GMP phosphodiesterase; Provisional
Pssm-ID: 183097 [Multi-domain] Cd Length: 799 Bit Score: 46.30 E-value: 4.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 119 VLDLQGRVVYVNPAFCRMVGWNESELLG----TLFPYPYWVEDKFEQHEKYLdivlsGKTPSSGMEMEAKRRDGSIFTAR 194
Cdd:PRK11359 151 VLDPERRIVQCNRAFTEMFGYCISEASGmqpdTLLNIPEFPADNRIRLQQLL-----WKTARDQDEFLLLTRTGEKIWIK 225
|
90 100 110
....*....|....*....|....*....|.
gi 648465101 195 LYVSPLMDPNGEQIGWMTSMTDITEPKRIRE 225
Cdd:PRK11359 226 ASISPVYDVLAHLQNLVMTFSDITEERQIRQ 256
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
359-566 |
7.49e-05 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 45.41 E-value: 7.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 359 SSLAHELNQPLTAIvNYNSAIAALIKSEHLDQERLLQVLDKSVsqaERAGRIIGRIRDFVR----RNEPERQAVKIDTIV 434
Cdd:PRK10337 242 SDAAHELRSPLAAL-KVQTEVAQLSDDDPQARKKALLQLHAGI---DRATRLVDQLLTLSRldslDNLQDVAEIPLEDLL 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 435 ENTMDLAFFESRKYSKQIEVNLPEDLPEVYADPILIEQVLLNLVKNGIEAMSQSEHETLYVNisqvglEIQVQVIDSGHG 514
Cdd:PRK10337 318 QSAVMDIYHTAQQAGIDVRLTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLN------ARNFTVRDNGPG 391
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 648465101 515 LKDP--ERLFEPFY---STKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFR 566
Cdd:PRK10337 392 VTPEalARIGERFYrppGQEATGSGLGLSIVRRIAKLHGMNVSFGNAPEGGFEAKVS 448
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
363-575 |
3.01e-04 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 43.67 E-value: 3.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 363 HELNQPLTAIVNYNSAIAALiKSEHLDQ----ERLLQVLD--------KSVSQAERAgrIIGRIRD-FVRRNEPERQAVK 429
Cdd:PRK15053 326 STLNAQLTQIKQYVESLRTL-RHEHLNWmstlNGLLQMKEydrvlemvQGESQAQQQ--LIDSLREaFADRQVAGLLFGK 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 430 IDTIVENTMDLAFFESRKYSKqievnLPEDLpevyaDPILIEQVLLNLVKNGIEA--MSQSEHETLYVNISQVGLEIQVQ 507
Cdd:PRK15053 403 VQRARELGLKMVIVPGSQLSQ-----LPPGL-----DSTEFAAIVGNLLDNAFEAslRSDEGNKIVELFLSDEGDDVVIE 472
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 648465101 508 VIDSGHGLKDP--ERLFEPFYSTKKEGL---GIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIPCYRKADN 575
Cdd:PRK15053 473 VADQGCGVPESlrDKIFEQGVSTRADEPgehGIGLYLIASYVTRCGGVITLEDNDPCGTLFSIFIPKVKPNDS 545
|
|
| PAS_7 |
pfam12860 |
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
111-222 |
7.47e-04 |
|
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya.
Pssm-ID: 432837 [Multi-domain] Cd Length: 115 Bit Score: 39.44 E-value: 7.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 111 NSMSTGMRVLDLQGRVVYVNPAFCRMVGWNESEL-----LGTLFPY-----PYWVEDKFEQHEKYLDIVLSGKTPSsgme 180
Cdd:pfam12860 2 ENMSQGLSVFDADLRLVAWNRRYRELLDLPEDLVqvgvpFEEIIRYnaergEYGPGDVEAHVRRRLAAARAGSPHY---- 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 648465101 181 MEAKRRDG---SIFTARLyvsplmdPNGeqiGWMTSMTDITEPKR 222
Cdd:pfam12860 78 FERERPDGrviEIRGNPL-------PDG---GFVTTFTDITERRR 112
|
|
| PAC |
smart00086 |
Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); PAC motif ... |
179-219 |
7.63e-04 |
|
Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); PAC motif occurs C-terminal to a subset of all known PAS motifs. It is proposed to contribute to the PAS domain fold.
Pssm-ID: 197509 Cd Length: 43 Bit Score: 37.55 E-value: 7.63e-04
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 648465101 179 MEMEAKRRDGSIFTARLYVSPLMDPNGEQIGWMTSMTDITE 219
Cdd:smart00086 2 VEYRLRRKDGSYIWVLVSASPIRDEDGEVEGILGVVRDITE 42
|
|
| PAS_3 |
pfam08447 |
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
126-210 |
9.49e-04 |
|
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya.
Pssm-ID: 430001 [Multi-domain] Cd Length: 89 Bit Score: 38.47 E-value: 9.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 126 VVYVNPAFCRMVGWNESELLGTL-----FPYPywvEDKfEQHEKYLDIVLSGKTPSSGmEMEAKRRDGSIFTARLYVSPL 200
Cdd:pfam08447 1 IIYWSPRFEEILGYTPEELLGKGeswldLVHP---DDR-ERVREALWEALKGGEPYSG-EYRIRRKDGEYRWVEARARPI 75
|
90
....*....|
gi 648465101 201 MDPNGEQIGW 210
Cdd:pfam08447 76 RDENGKPVRV 85
|
|
| PRK13560 |
PRK13560 |
hypothetical protein; Provisional |
92-241 |
2.06e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 106506 [Multi-domain] Cd Length: 807 Bit Score: 41.20 E-value: 2.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 92 RSEAEEQLFLETTFRRAMENSMSTGMRVLDLQGRVVYVNPAFCRMVGWNESELLGTL---FPYPYWVEDKFEqhekyLDI 168
Cdd:PRK13560 192 RKRAEERIDEALHFLQQLLDNIADPAFWKDEDAKVFGCNDAACLACGFRREEIIGMSihdFAPAQPADDYQE-----ADA 266
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 648465101 169 VLSGKTPSSGMEMEAKRRDGSIFTA--RLYVSPLMDPNGEQIGWMTSMTDITEPKRIREALTAAHERFMTVLESL 241
Cdd:PRK13560 267 AKFDADGSQIIEAEFQNKDGRTRPVdvIFNHAEFDDKENHCAGLVGAITDISGRRAAERELLEKEDMLRAIIEAA 341
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
307-568 |
2.16e-03 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 40.76 E-value: 2.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 307 VQHRTLNWTDGRkvRLQVARDISQRReyeqklsaqqekvQLSG--RlstlgEMASSLAHELNQPLTAIVNYnsaiaalik 384
Cdd:PRK11006 175 LEIRVMPYTEGQ--LLMVARDVTQMH-------------QLEGarR-----NFFANVSHELRTPLTVLQGY--------- 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 385 sehldqerlLQVLDKSVSQAERAGRIIGRIRDfvrrneperQAVKIDTIVENTMDLAFFESrkySKQIEVNLPEDLPevy 464
Cdd:PRK11006 226 ---------LEMMQDQPLEGALREKALHTMRE---------QTQRMEGLVKQLLTLSKIEA---APTIDLNEKVDVP--- 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 465 adpilieqVLLNLVKNGIEAMSQSEHETLY--------------------------VNISQVGLEIQV-----------Q 507
Cdd:PRK11006 282 --------MMLRVLEREAQTLSQGKHTITFevdnslkvfgnedqlrsaisnlvynaVNHTPEGTHITVrwqrvpqgaefS 353
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465101 508 VIDSGHGLKdPE---RLFEPFYSTKKE------GLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRIP 568
Cdd:PRK11006 354 VEDNGPGIA-PEhipRLTERFYRVDKArsrqtgGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLP 422
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
528-567 |
2.39e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 38.38 E-value: 2.39e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 648465101 528 TKKEGLGIGLNICRSIIESHRGRLWAENNPSGGTIFTFRI 567
Cdd:cd16954 96 EQRPGQGLGLAIAKEIVEQYGGELSLSDSPLGGARFEVVF 135
|
|
| |
