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Conserved domains on  [gi|654271245|ref|WP_027786399|]
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MULTISPECIES: FAD-binding oxidoreductase [Burkholderia]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11429741)

FAD/NAD(P)-binding oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.30.9.10
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0050660
SCOP:  3000055

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
18-364 2.72e-76

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


:

Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 239.81  E-value: 2.72e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  18 MALAWGIARLGQRVAVCDGDDIAFRAARGNFGLVWVQGKGGRCLPYARWSCESSSRWHafsaQLQRETGVDCAFERPGGI 97
Cdd:COG0665   15 LSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPGLAALADRALVRLAREALDLWR----ELAAELGIDCDFRRTGVL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  98 ELFEHRAELDSATDLLESLRRRDaaLSYEVLDPAALRRRIPS-ASPSLAGALWSPNDGHANPLHTLRAMLLAFQQCGGVY 176
Cdd:COG0665   91 YLARTEAELAALRAEAEALRALG--LPVELLDAAELREREPGlGSPDYAGGLYDPDDGHVDPAKLVRALARAARAAGVRI 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 177 LPRSDVTEIRPRAGRFE-IDTRHARLEAGRVVLAAGLDNARLAPMVDLRAPISPLRGQIMVTERLAPFLDYPTL-----V 250
Cdd:COG0665  169 REGTPVTGLEREGGRVTgVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVTEPLPDLPLRPVLddtgvY 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 251 VRQTREGSVLLGDSAEDVGFDDGQTRPAMVDIARRARTAFPALAHARIVRAWGALRIMTPDGLPIYEASATHPGAFIAIC 330
Cdd:COG0665  249 LRPTADGRLLVGGTAEPAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATG 328

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 654271245 331 HS--GVTLAATHADLVAPWIAGRAAPADLSAFTTAR 364
Cdd:COG0665  329 HGghGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
18-364 2.72e-76

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 239.81  E-value: 2.72e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  18 MALAWGIARLGQRVAVCDGDDIAFRAARGNFGLVWVQGKGGRCLPYARWSCESSSRWHafsaQLQRETGVDCAFERPGGI 97
Cdd:COG0665   15 LSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPGLAALADRALVRLAREALDLWR----ELAAELGIDCDFRRTGVL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  98 ELFEHRAELDSATDLLESLRRRDaaLSYEVLDPAALRRRIPS-ASPSLAGALWSPNDGHANPLHTLRAMLLAFQQCGGVY 176
Cdd:COG0665   91 YLARTEAELAALRAEAEALRALG--LPVELLDAAELREREPGlGSPDYAGGLYDPDDGHVDPAKLVRALARAARAAGVRI 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 177 LPRSDVTEIRPRAGRFE-IDTRHARLEAGRVVLAAGLDNARLAPMVDLRAPISPLRGQIMVTERLAPFLDYPTL-----V 250
Cdd:COG0665  169 REGTPVTGLEREGGRVTgVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVTEPLPDLPLRPVLddtgvY 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 251 VRQTREGSVLLGDSAEDVGFDDGQTRPAMVDIARRARTAFPALAHARIVRAWGALRIMTPDGLPIYEASATHPGAFIAIC 330
Cdd:COG0665  249 LRPTADGRLLVGGTAEPAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATG 328

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 654271245 331 HS--GVTLAATHADLVAPWIAGRAAPADLSAFTTAR 364
Cdd:COG0665  329 HGghGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 19-345 3.75e-46

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 161.03  E-value: 3.75e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245   19 ALAWGIARLGQRVAVCD-GDDIAFRAARGNFGLVWVQGKGGRCLPYARWSCESSSRWhafsAQLQRETGVDCAFERPGGI 97
Cdd:pfam01266  13 STAYELARRGLSVTLLErGDDPGSGASGRNAGLIHPGLRYLEPSELARLALEALDLW----EELEEELGIDCGFRRCGVL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245   98 ELFeHRAELDSATDLLESLRRRDAAlsYEVLDPAALRRRIPsASPSLAGALWSPNDGHANPLHTLRAMLLAFQQCGGVYL 177
Cdd:pfam01266  89 VLA-RDEEEEALEKLLAALRRLGVP--AELLDAEELRELEP-LLPGLRGGLFYPDGGHVDPARLLRALARAAEALGVRII 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  178 PRSDVTEIRPRAGRFEIDTRHarlEAGRVVLAAGLdNARLAPMVDLRAPISPLRGQIMVTERLA----------PFLDYP 247
Cdd:pfam01266 165 EGTEVTGIEEEGGVWGVVTTG---EADAVVNAAGA-WADLLALPGLRLPVRPVRGQVLVLEPLPeallilpvpiTVDPGR 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  248 TLVVRQTREGSVLLGDSAEDVGFDDGQTRPAMVD-IARRARTAFPALahARIVRAWGALRiMTPDGLPIYEAsATHPGAF 326
Cdd:pfam01266 241 GVYLRPRADGRLLLGGTDEEDGFDDPTPDPEEIEeLLEAARRLFPAL--ADIERAWAGLR-PLPDGLPIIGR-PGSPGLY 316

                         330       340
                  ....*....|....*....|.
gi 654271245  327 IAICHS--GVTLAATHADLVA 345
Cdd:pfam01266 317 LATGHGghGLTLAPGIGKLLA 337
thiamin_ThiO TIGR02352
glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine ...
 22-351 1.31e-30

glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine]


Pssm-ID: 274092 [Multi-domain]  Cd Length: 337  Bit Score: 119.39  E-value: 1.31e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245   22 WGIARLGQRVAVCDGDDIAFRAARGNFGLVWVQGKG----GRCLPYARwscESSSRWHAFSAQLQRETGVDCAFERPGGI 97
Cdd:TIGR02352   1 WELAKRGHSVTLFDRDPMGGGASWAAAGMLAPHAECeyaeDPLFDLAL---ESLRLYPEWLEALKELTGLDTGYHQCGTL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245   98 ELFEHRAELDSatdlLESLRRRDAALSYEV--LDPAALRRRIPSASPSLAGALWSPNDGHANPLHTLRAMLLAFQQCGGV 175
Cdd:TIGR02352  78 VVAFDEDDVEH----LRQLADLQSATGMEVewLSGRALRRLEPYLSGGIRGAVFYPDDAHVDPRALLKALEKALEKLGVE 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  176 YLPRSDVTEIRPRAGRFE-IDTRHARLEAGRVVLAAGLDNARLAPMvdlraPISPLRGQIM-VTERLAPFLDYP-TLVVR 252
Cdd:TIGR02352 154 IIEHTEVQHIEIRGEKVTaIVTPSGDVQADQVVLAAGAWAGELLPL-----PLRPVRGQPLrLEAPAVPLLNRPlRAVVY 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  253 QTR-------EGSVLLGDSAEDVGFDDGQTRPAMVDIARRARTAFPALAHARIVRAWGALRIMTPDGLPIYEASATHPGA 325
Cdd:TIGR02352 229 GRRvyivprrDGRLVVGATMEESGFDTTPTLGGIKELLRDAYTILPALKEARLLETWAGLRPGTPDNLPYIGEHPEDRRL 308

                         330       340
                  ....*....|....*....|....*...
gi 654271245  326 FIAICH--SGVTLAATHADLVAPWIAGR 351
Cdd:TIGR02352 309 LIATGHyrNGILLAPATAEVIADLILGK 336
PRK00711 PRK00711
D-amino acid dehydrogenase;
80-360 2.24e-15

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 76.76  E-value: 2.24e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  80 QLQRETGVDCAFERPGGIELFEHRAELDSATDLLESLRRrdAALSYEVLDPAALRRRIP---SASPSLAGALWSPND--G 154
Cdd:PRK00711 121 ALRAETGIQYEGRQGGTLQLFRTQQQLDAAAKDIAVLEE--AGVPYELLDRDELAAVEPalaGVRHKLVGGLRLPNDetG 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 155 HANpLHTLRAMLLAfQQCGGVYLPRSDVTEIRPRAGRFE-IDTRHARLEAGRVVLAAGLDNARLAPMVDLRAPISPLRGQ 233
Cdd:PRK00711 199 DCQ-LFTQRLAAMA-EQLGVKFRFNTPVDGLLVEGGRITgVQTGGGVITADAYVVALGSYSTALLKPLGVDIPVYPLKGY 276

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 234 I----MVTERLAPF---LDYpTLVVRQTREGSVL-LGDSAEDVGFDDGqtrpamVDIARRA------RTAFPALAHARIV 299
Cdd:PRK00711 277 SltvpITDEDRAPVstvLDE-TYKIAITRFDDRIrVGGMAEIVGFDLR------LDPARREtlemvvRDLFPGGGDLSQA 349

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 654271245 300 RAWGALRIMTPDGLPIYEASAtHPGAFIAICHS--GVTLAATHADLVAPWIAGRA---APADLSAF 360
Cdd:PRK00711 350 TFWTGLRPMTPDGTPIVGATR-YKNLWLNTGHGtlGWTMACGSGQLLADLISGRKpaiDADDLSVA 414
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
18-364 2.72e-76

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 239.81  E-value: 2.72e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  18 MALAWGIARLGQRVAVCDGDDIAFRAARGNFGLVWVQGKGGRCLPYARWSCESSSRWHafsaQLQRETGVDCAFERPGGI 97
Cdd:COG0665   15 LSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLRPGLAALADRALVRLAREALDLWR----ELAAELGIDCDFRRTGVL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  98 ELFEHRAELDSATDLLESLRRRDaaLSYEVLDPAALRRRIPS-ASPSLAGALWSPNDGHANPLHTLRAMLLAFQQCGGVY 176
Cdd:COG0665   91 YLARTEAELAALRAEAEALRALG--LPVELLDAAELREREPGlGSPDYAGGLYDPDDGHVDPAKLVRALARAARAAGVRI 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 177 LPRSDVTEIRPRAGRFE-IDTRHARLEAGRVVLAAGLDNARLAPMVDLRAPISPLRGQIMVTERLAPFLDYPTL-----V 250
Cdd:COG0665  169 REGTPVTGLEREGGRVTgVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVTEPLPDLPLRPVLddtgvY 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 251 VRQTREGSVLLGDSAEDVGFDDGQTRPAMVDIARRARTAFPALAHARIVRAWGALRIMTPDGLPIYEASATHPGAFIAIC 330
Cdd:COG0665  249 LRPTADGRLLVGGTAEPAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATG 328

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 654271245 331 HS--GVTLAATHADLVAPWIAGRAAPADLSAFTTAR 364
Cdd:COG0665  329 HGghGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 19-345 3.75e-46

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 161.03  E-value: 3.75e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245   19 ALAWGIARLGQRVAVCD-GDDIAFRAARGNFGLVWVQGKGGRCLPYARWSCESSSRWhafsAQLQRETGVDCAFERPGGI 97
Cdd:pfam01266  13 STAYELARRGLSVTLLErGDDPGSGASGRNAGLIHPGLRYLEPSELARLALEALDLW----EELEEELGIDCGFRRCGVL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245   98 ELFeHRAELDSATDLLESLRRRDAAlsYEVLDPAALRRRIPsASPSLAGALWSPNDGHANPLHTLRAMLLAFQQCGGVYL 177
Cdd:pfam01266  89 VLA-RDEEEEALEKLLAALRRLGVP--AELLDAEELRELEP-LLPGLRGGLFYPDGGHVDPARLLRALARAAEALGVRII 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  178 PRSDVTEIRPRAGRFEIDTRHarlEAGRVVLAAGLdNARLAPMVDLRAPISPLRGQIMVTERLA----------PFLDYP 247
Cdd:pfam01266 165 EGTEVTGIEEEGGVWGVVTTG---EADAVVNAAGA-WADLLALPGLRLPVRPVRGQVLVLEPLPeallilpvpiTVDPGR 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  248 TLVVRQTREGSVLLGDSAEDVGFDDGQTRPAMVD-IARRARTAFPALahARIVRAWGALRiMTPDGLPIYEAsATHPGAF 326
Cdd:pfam01266 241 GVYLRPRADGRLLLGGTDEEDGFDDPTPDPEEIEeLLEAARRLFPAL--ADIERAWAGLR-PLPDGLPIIGR-PGSPGLY 316

                         330       340
                  ....*....|....*....|.
gi 654271245  327 IAICHS--GVTLAATHADLVA 345
Cdd:pfam01266 317 LATGHGghGLTLAPGIGKLLA 337
thiamin_ThiO TIGR02352
glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine ...
 22-351 1.31e-30

glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine]


Pssm-ID: 274092 [Multi-domain]  Cd Length: 337  Bit Score: 119.39  E-value: 1.31e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245   22 WGIARLGQRVAVCDGDDIAFRAARGNFGLVWVQGKG----GRCLPYARwscESSSRWHAFSAQLQRETGVDCAFERPGGI 97
Cdd:TIGR02352   1 WELAKRGHSVTLFDRDPMGGGASWAAAGMLAPHAECeyaeDPLFDLAL---ESLRLYPEWLEALKELTGLDTGYHQCGTL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245   98 ELFEHRAELDSatdlLESLRRRDAALSYEV--LDPAALRRRIPSASPSLAGALWSPNDGHANPLHTLRAMLLAFQQCGGV 175
Cdd:TIGR02352  78 VVAFDEDDVEH----LRQLADLQSATGMEVewLSGRALRRLEPYLSGGIRGAVFYPDDAHVDPRALLKALEKALEKLGVE 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  176 YLPRSDVTEIRPRAGRFE-IDTRHARLEAGRVVLAAGLDNARLAPMvdlraPISPLRGQIM-VTERLAPFLDYP-TLVVR 252
Cdd:TIGR02352 154 IIEHTEVQHIEIRGEKVTaIVTPSGDVQADQVVLAAGAWAGELLPL-----PLRPVRGQPLrLEAPAVPLLNRPlRAVVY 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  253 QTR-------EGSVLLGDSAEDVGFDDGQTRPAMVDIARRARTAFPALAHARIVRAWGALRIMTPDGLPIYEASATHPGA 325
Cdd:TIGR02352 229 GRRvyivprrDGRLVVGATMEESGFDTTPTLGGIKELLRDAYTILPALKEARLLETWAGLRPGTPDNLPYIGEHPEDRRL 308

                         330       340
                  ....*....|....*....|....*...
gi 654271245  326 FIAICH--SGVTLAATHADLVAPWIAGR 351
Cdd:TIGR02352 309 LIATGHyrNGILLAPATAEVIADLILGK 336
PRK00711 PRK00711
D-amino acid dehydrogenase;
80-360 2.24e-15

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 76.76  E-value: 2.24e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  80 QLQRETGVDCAFERPGGIELFEHRAELDSATDLLESLRRrdAALSYEVLDPAALRRRIP---SASPSLAGALWSPND--G 154
Cdd:PRK00711 121 ALRAETGIQYEGRQGGTLQLFRTQQQLDAAAKDIAVLEE--AGVPYELLDRDELAAVEPalaGVRHKLVGGLRLPNDetG 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 155 HANpLHTLRAMLLAfQQCGGVYLPRSDVTEIRPRAGRFE-IDTRHARLEAGRVVLAAGLDNARLAPMVDLRAPISPLRGQ 233
Cdd:PRK00711 199 DCQ-LFTQRLAAMA-EQLGVKFRFNTPVDGLLVEGGRITgVQTGGGVITADAYVVALGSYSTALLKPLGVDIPVYPLKGY 276

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 234 I----MVTERLAPF---LDYpTLVVRQTREGSVL-LGDSAEDVGFDDGqtrpamVDIARRA------RTAFPALAHARIV 299
Cdd:PRK00711 277 SltvpITDEDRAPVstvLDE-TYKIAITRFDDRIrVGGMAEIVGFDLR------LDPARREtlemvvRDLFPGGGDLSQA 349

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 654271245 300 RAWGALRIMTPDGLPIYEASAtHPGAFIAICHS--GVTLAATHADLVAPWIAGRA---APADLSAF 360
Cdd:PRK00711 350 TFWTGLRPMTPDGTPIVGATR-YKNLWLNTGHGtlGWTMACGSGQLLADLISGRKpaiDADDLSVA 414
solA PRK11259
N-methyl-L-tryptophan oxidase;
80-367 6.42e-11

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 63.32  E-value: 6.42e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  80 QLQRETGVDcAFERPGGIELfehrAELDSATdLLESLRR-RDAALSYEVLDPAALRRRIPS-ASPSLAGALWSPNDGHAN 157
Cdd:PRK11259  74 ELERESGEP-LFVRTGVLNL----GPADSDF-LANSIRSaRQHGLPHEVLDAAEIRRRFPQfRLPDGYIALFEPDGGFLR 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 158 PLHTLRAMLLAFQQCGGVYLPRSDVTEIRPRAGRFEIDTRHARLEAGRVVLAAGLDNARLAPmvDLRAPISPLRgQIM-- 235
Cdd:PRK11259 148 PELAIKAHLRLAREAGAELLFNEPVTAIEADGDGVTVTTADGTYEAKKLVVSAGAWVKDLLP--PLELPLTPVR-QVLaw 224

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 236 --VTERLAPFLDYPTLVVrQTREGSVLLGDSAEDVG------FDDGQTRPAMVDIARRARTA------FPALAH-----A 296
Cdd:PRK11259 225 fqADGRYSEPNRFPAFIW-EVPDGDQYYGFPAENGPglkigkHNGGQEITSPDERDRFVTVAedgaelRPFLRNylpgvG 303

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 297 RIVRAWGALRIMTPDGLPIYeasATHPGafiaicHSGVTLAA-------THA----DLVAPWIAGRAAPADLSAFTTARF 365
Cdd:PRK11259 304 PCLRGAACTYTNTPDEHFII---DTLPG------HPNVLVASgcsghgfKFAsvlgEILADLAQDGTSDFDLSPFSLSRF 374


                 ..
gi 654271245 366 AA 367
Cdd:PRK11259 375 AA 376
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
13-268 5.98e-09

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 57.08  E-value: 5.98e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  13 GGLVGMALAWGIARL-GQRVAVCD-GDDIAFRAARGN-----FGLVWVQG--KGGRCLpyarwscESSSRWHAFSAQLqr 83
Cdd:COG0579   12 AGIVGLALARELSRYeDLKVLVLEkEDDVAQESSGNNsgvihAGLYYTPGslKARLCV-------EGNELFYELCREL-- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  84 etgvDCAFERPGGIELFEHRAEldsatdlLESLRRRDAALS------YEVLDPAALRRRIPSASPSLAGALWSPNDGHAN 157
Cdd:COG0579   83 ----GIPFKRCGKLVVATGEEE-------VAFLEKLYERGKangvpgLEILDREELRELEPLLSDEGVAALYSPSTGIVD 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 158 PLHTLRAMLLAFQQCGGVYLPRSDVTEIRPRAGRFEIDTRHARLEAGRVVLAAGLDNARLAPMVDLRAPIS--PLRGQIM 235
Cdd:COG0579  152 PGALTRALAENAEANGVELLLNTEVTGIEREGDGWEVTTNGGTIRARFVINAAGLYADRLAQMAGIGKDFGifPVKGEYL 231

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 654271245 236 VTERLA----------PFLDYPTLVVRQTR--EGSVLLGDSAEDV 268
Cdd:COG0579  232 VLDKPAelvnakvypvPDPGAPFLGVHLTRtiDGNLLFGPNAVFV 276
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 86-356 3.82e-07

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 51.56  E-value: 3.82e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  86 GVDCAFERPGGIELFEHRAELDSATDLLESLRRrdAALSYEVLDPAALRRRIPSASPSLAGALWSPNDGHANPLHTLRAM 165
Cdd:PRK12409 126 GIDFDLERRGILHIYHDKAGFDHAKRVNALLAE--GGLERRAVTPEEMRAIEPTLTGEYYGGYYTPSDSTGDIHKFTTGL 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 166 LLAFQQCGGVYLPRSDVTEIRPRAGRFEI------DTRHARLEAGRVVLAAGLDNARLAPMVDLRAPISPLRG-QIMV-- 236
Cdd:PRK12409 204 AAACARLGVQFRYGQEVTSIKTDGGGVVLtvqpsaEHPSRTLEFDGVVVCAGVGSRALAAMLGDRVNVYPVKGySITVnl 283

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 237 ----TERLAP---FLDYPTLVVrQTREGSVLL--GDSAEDVGFD----DGQTRPaMVDIARRArtaFPALAHARIVrAWG 303
Cdd:PRK12409 284 ddeaSRAAAPwvsLLDDSAKIV-TSRLGADRFrvAGTAEFNGYNrdirADRIRP-LVDWVRRN---FPDVSTRRVV-PWA 357

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 654271245 304 ALRIMTPDGLPIYEASAtHPGAFIAICHS--GVTLAATHADLVAPWIAgRAAPAD 356
Cdd:PRK12409 358 GLRPMMPNMMPRVGRGR-RPGVFYNTGHGhlGWTLSAATADLVAQVVA-QKLPAP 410
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
109-265 1.42e-06

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 49.82  E-value: 1.42e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 109 ATD-----LLESLRRRDAA--LSYEVLDPAALRRRIPSASPslAGALWSPNDGHANPLHTLRAMLLAFQQCGGVYLPRSD 181
Cdd:PRK11728  94 ATSeleleRMEALYERARAngIEVERLDAEELREREPNIRG--LGAIFVPSTGIVDYRAVAEAMAELIQARGGEIRLGAE 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 182 VTEIRPRAGRFEIDTRHARLEAGRVVLAAGLDNARLAPM--VDLRAPISPLRGQIMvteRLAPFL--------------D 245
Cdd:PRK11728 172 VTALDEHANGVVVRTTQGEYEARTLINCAGLMSDRLAKMagLEPDFRIVPFRGEYY---RLAPEKnqlvnhliypvpdpA 248

                        170       180
                 ....*....|....*....|..
gi 654271245 246 YPTLVVRQTR--EGSVLLGDSA 265
Cdd:PRK11728 249 FPFLGVHLTRmiDGSVTVGPNA 270
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 63-231 2.24e-06

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 49.06  E-value: 2.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245   63 YARWSCESSSRWhafsAQLQRETGVDcaFERPGGIELFeHRAELDSATDLLESLRRRdaALSYEVLDPAALRRRIPSAS- 141
Cdd:TIGR01377  57 YTPMMLECYQLW----AQLEKEAGTK--LHRQTGLLLL-GPKENQFLKTIQATLSRH--GLEHELLSSKQLKQRFPNIRv 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245  142 PSLAGALWSPNDGHANPLHTLRAMLLAFQQCGGVYLPRSDVTEIRPRAGRFEIDTRHARLEAGRVVLAAGLDNARLAPMV 221
Cdd:TIGR01377 128 PRNEVGLLDPNGGVLYAEKALRALQELAEAHGATVRDGTKVVEIEPTELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPL 207

                         170
                  ....*....|
gi 654271245  222 DLRAPISPLR 231
Cdd:TIGR01377 208 GIEIPLQPLR 217
glpA PRK11101
anaerobic glycerol-3-phosphate dehydrogenase subunit A;
119-306 6.02e-06

anaerobic glycerol-3-phosphate dehydrogenase subunit A;


Pssm-ID: 236847 [Multi-domain]  Cd Length: 546  Bit Score: 48.09  E-value: 6.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 119 RDAALSYEVLDPAALRRRIPSASPSLAGALWSPnDGHANPLHTLRAMLLAFQQCGGVYLPRSDVTEIRPRAGR------F 192
Cdd:PRK11101 110 EEAGIEAEAIDPQQALILEPAVNPALIGAVKVP-DGTVDPFRLTAANMLDAKEHGAQILTYHEVTGLIREGDTvcgvrvR 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 193 EIDTRHAR-LEAGRVVLAAGLDNARLAPMVDLRAPISPLRGQIMVterlapfLDY--PTLVVRQTREGS----------- 258
Cdd:PRK11101 189 DHLTGETQeIHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLI-------MDHriNNHVINRCRKPAdadilvpgdti 261

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 654271245 259 VLLGDSAEDVGF---DDGQTRPAMVDIARR--ARTAfPALAHARIVRAWGALR 306
Cdd:PRK11101 262 SLIGTTSTRIDYdqiDDNRVTAEEVDILLRegEKLA-PVMAKTRILRAYAGVR 313
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 128-365 2.31e-03

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 39.83  E-value: 2.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 128 LDPAALRRRIPSASPslAGALWSPNDGHANPLhTLRAMLLAFQQCGGVYLPRSDVTEIRPRAGRFEIDTRHARL-EAGRV 206
Cdd:PRK01747 379 LDAEEAEELAGLPVP--CGGIFYPQGGWLCPA-ELCRALLALAGQQLTIHFGHEVARLEREDDGWQLDFAGGTLaSAPVV 455

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 207 VLAAGLDNARLAPMVDLraPISPLRGQimVTeRLAPFLDYPTL---------VVRQTREGSVLLGDSaedvgFDDGQTRP 277
Cdd:PRK01747 456 VLANGHDAARFAQTAHL--PLYSVRGQ--VS-HLPTTPALSALkqvlcydgyLTPQPANGTHCIGAS-----YDRDDTDT 525

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654271245 278 AM---VDIARRARTA--FPALAHA-----RIVRAWGALRIMTPDGLPI------YEASAT----------------HPGA 325
Cdd:PRK01747 526 AFreaDHQENLERLAecLPQALWAkevdvSALQGRVGFRCASRDRLPMvgnvpdEAATLAeyaalanqqpardaprLPGL 605

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 654271245 326 FIAICHS--GVTLAATHADLVAPWIAGRAAPAD---LSAFTTARF 365
Cdd:PRK01747 606 YVAGALGsrGLCSAPLGAELLASQIEGEPLPLErdlLAALHPNRF 650
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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