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Conserved domains on  [gi|654544409|ref|WP_028012117|]
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MULTISPECIES: peptide antibiotic transporter SbmA [Enterobacter]

Protein Classification

peptide transporter( domain architecture ID 10013728)

peptide transporter similar to peptide antibiotic transporter SbmA, which is involved in the uptake of antimicrobial peptides such as microcin B17, microcin 25, and bleomycin

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK11098 PRK11098
peptide antibiotic transporter SbmA;
1-406 0e+00

peptide antibiotic transporter SbmA;


:

Pssm-ID: 182960  Cd Length: 409  Bit Score: 741.82  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409   1 MFKSFFPKPGPFFLSAFIWALIAVVFWLAGGGAWLTRIVG---ATGEVPISAARFWSFSYLLFYAYYALCVGLFALFWFN 77
Cdd:PRK11098   1 MFKSFFPKPKLFFLSAFVWALIAVIFWYAGGGDWLARLTGlaaASGQLPIGAARFWSPDFLWFYAYYLVCVGLFAGFWFI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409  78 YSPHRWQTWSILGTSLIIFVTWFLVEVSVAINAWYAPFYDLIQKALSAPNRVPIGELYNQLKIFMGIAMIAVTVAVLNNF 157
Cdd:PRK11098  81 YSPHPWQRWSILGSALIIFVTWFLVQVSVAVNAWYAPFYDLIQTALSSPGKVTIGQFYSEVGVFLGIALIAVVISVLNNF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 158 FVSHYVFRWRTAMNEFYMTHWERLRHIEGAAQRVQEDTMRFASTLEDMGVSLLNAILKLFAFLPILVALSPHISALPIVG 237
Cdd:PRK11098 161 FVSHYVFRWRTAMNEYYMAHWQKLRHIEGAAQRVQEDTMRFASTLENLGVSFINAIMTLIAFLPVLVTLSAHVPELPIVG 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 238 HLPYGLLIPALIWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDPTRAAPPTIKELFRNVRFNYFRLYFHYM 317
Cdd:PRK11098 241 HIPYGLVIAAIVWSLFGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDADRATPPTVRELFSNVRKNYFRLYFHYM 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 318 YFNIARIFYLQVDTVFGLFLLFPSIVAGTITLGLLTQITNVFDQVRNSFQYLINSWTTLVELMSIYKRLRSFEHELDDRD 397
Cdd:PRK11098 321 YFNIARILYLQVDNVFGLFLLFPSIVAGTITLGLMTQITNVFGQVRGSFQYLINSWTTIVELLSIYKRLRSFEAALDGEP 400

                 ....*....
gi 654544409 398 LQEVTNTFS 406
Cdd:PRK11098 401 LQEVDHTLL 409
 
Name Accession Description Interval E-value
PRK11098 PRK11098
peptide antibiotic transporter SbmA;
1-406 0e+00

peptide antibiotic transporter SbmA;


Pssm-ID: 182960  Cd Length: 409  Bit Score: 741.82  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409   1 MFKSFFPKPGPFFLSAFIWALIAVVFWLAGGGAWLTRIVG---ATGEVPISAARFWSFSYLLFYAYYALCVGLFALFWFN 77
Cdd:PRK11098   1 MFKSFFPKPKLFFLSAFVWALIAVIFWYAGGGDWLARLTGlaaASGQLPIGAARFWSPDFLWFYAYYLVCVGLFAGFWFI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409  78 YSPHRWQTWSILGTSLIIFVTWFLVEVSVAINAWYAPFYDLIQKALSAPNRVPIGELYNQLKIFMGIAMIAVTVAVLNNF 157
Cdd:PRK11098  81 YSPHPWQRWSILGSALIIFVTWFLVQVSVAVNAWYAPFYDLIQTALSSPGKVTIGQFYSEVGVFLGIALIAVVISVLNNF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 158 FVSHYVFRWRTAMNEFYMTHWERLRHIEGAAQRVQEDTMRFASTLEDMGVSLLNAILKLFAFLPILVALSPHISALPIVG 237
Cdd:PRK11098 161 FVSHYVFRWRTAMNEYYMAHWQKLRHIEGAAQRVQEDTMRFASTLENLGVSFINAIMTLIAFLPVLVTLSAHVPELPIVG 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 238 HLPYGLLIPALIWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDPTRAAPPTIKELFRNVRFNYFRLYFHYM 317
Cdd:PRK11098 241 HIPYGLVIAAIVWSLFGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDADRATPPTVRELFSNVRKNYFRLYFHYM 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 318 YFNIARIFYLQVDTVFGLFLLFPSIVAGTITLGLLTQITNVFDQVRNSFQYLINSWTTLVELMSIYKRLRSFEHELDDRD 397
Cdd:PRK11098 321 YFNIARILYLQVDNVFGLFLLFPSIVAGTITLGLMTQITNVFGQVRGSFQYLINSWTTIVELLSIYKRLRSFEAALDGEP 400

                 ....*....
gi 654544409 398 LQEVTNTFS 406
Cdd:PRK11098 401 LQEVDHTLL 409
SbmA COG1133
Peptide antibiotic transporter SbmA/BacA, ABC-type permease family [Defense mechanisms];
1-401 0e+00

Peptide antibiotic transporter SbmA/BacA, ABC-type permease family [Defense mechanisms];


Pssm-ID: 440748  Cd Length: 408  Bit Score: 725.95  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409   1 MFKSFFPKPGPFFLSAFIWALIAVVFWLAGGGAWLTRIV----GATGEVPISAARFWSFSYLLFYAYYALCVGLFALFWF 76
Cdd:COG1133    1 MFKSFFPRPKLFFLSAAIWSLLAVLFWYAGGEGLGASLGlppaAAGAPPPIGAARFWTPDFLWFYAYYALCVGLFAGFWF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409  77 NYSPHRWQTWSILGTSLIIFVTWFLVEVSVAINAWYAPFYDLIQKALSAPNRVPIGELYNQLKIFMGIAMIAVTVAVLNN 156
Cdd:COG1133   81 FYSPHRWQRWSILGSALIIFVTYFSVQVSVAINAWYGPFYDLIQKALSKPGSVTIADFYGQMLTFLGIALIAVTVGVLNA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 157 FFVSHYVFRWRTAMNEFYMTHWERLRHIEGAAQRVQEDTMRFASTLEDMGVSLLNAILKLFAFLPILVALSPHISALPIV 236
Cdd:COG1133  161 FFVSHYVFRWRTAMNDYYMAHWPRLRHIEGASQRVQEDTMRFASIVEGLGVSFIDAVMTLIAFLPVLWALSQHVTELPII 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 237 GHLPYGLLIPALIWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDPTRAAPPTIKELFRNVRFNYFRLYFHY 316
Cdd:COG1133  241 GEVPYSLVWAAIFWSLFGTVLLALVGIKLPGLEFRNQRVEAAYRKELVYGEDDAERAQPPTVRELFSNVRRNYFRLYFHY 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 317 MYFNIARIFYLQVDTVFGLFLLFPSIVAGTITLGLLTQITNVFDQVRNSFQYLINSWTTLVELMSIYKRLRSFEHELDDR 396
Cdd:COG1133  321 LYFNVARYLYLQADNIFPLFILVPSIVAGKITLGLMQQISNAFGQVRSSFQYLVNSWTTIVELLSIYKRLRAFEAAIDDE 400

                 ....*
gi 654544409 397 DLQEV 401
Cdd:COG1133  401 PLPEI 405
SbmA_BacA pfam05992
SbmA/BacA-like family; The Rhizobium meliloti bacA gene encodes a function that is essential ...
80-393 0e+00

SbmA/BacA-like family; The Rhizobium meliloti bacA gene encodes a function that is essential for bacterial differentiation into bacteroids within plant cells in the symbiosis between R. meliloti and alfalfa. An Escherichia coli homolog of BacA, SbmA, is implicated in the uptake of microcins and bleomycin. This family is likely to be a subfamily of the ABC transporter family.


Pssm-ID: 461797 [Multi-domain]  Cd Length: 314  Bit Score: 532.38  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409   80 PHRWQTWSILGTSLIIFVTWFLVEVSVAINAWYAPFYDLIQKALSAPNRVPIGELYNQLKIFMGIAMIAVTVAVLNNFFV 159
Cdd:pfam05992   1 PHKWQLWSILGTALILFVTWFQVQVDVAINAWYGPFYDLIQKALASPNAVTIGEFYASLLVFLGIAFIYVTIAVLNLFFV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409  160 SHYVFRWRTAMNEFYMTHWERLRHIEGAAQRVQEDTMRFASTLEDMGVSLLNAILKLFAFLPILVALSPHISALPIVGHL 239
Cdd:pfam05992  81 SHYVFRWRTAMNDYYTSHWQQLRHIEGASQRVQEDTMRFASIVEDLGVSLVRAIMTLIAFLPVLFGLSKHVPVLPIIGDI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409  240 PYGLLIPALIWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDPTRAAPPTIKELFRNVRFNYFRLYFHYMYF 319
Cdd:pfam05992 161 PHSLVWAAVVWSLGGTVFLAVVGIKLPGLEFNNQKVEAAYRKELVYGEDDATRATPKTLKELFSDVRKNYFRLYFHYMYF 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 654544409  320 NIARIFYLQVDTVFGLFLLFPSIVAGTITLGLLTQITNVFDQVRNSFQYLINSWTTLVELMSIYKRLRSFEHEL 393
Cdd:pfam05992 241 NIARIFYLQLDNLFGYIFLAPSIVAGKITLGVMQQITNVFGKVRGSFQYLINSWTTIVELMSIYKRLRAFESVI 314
 
Name Accession Description Interval E-value
PRK11098 PRK11098
peptide antibiotic transporter SbmA;
1-406 0e+00

peptide antibiotic transporter SbmA;


Pssm-ID: 182960  Cd Length: 409  Bit Score: 741.82  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409   1 MFKSFFPKPGPFFLSAFIWALIAVVFWLAGGGAWLTRIVG---ATGEVPISAARFWSFSYLLFYAYYALCVGLFALFWFN 77
Cdd:PRK11098   1 MFKSFFPKPKLFFLSAFVWALIAVIFWYAGGGDWLARLTGlaaASGQLPIGAARFWSPDFLWFYAYYLVCVGLFAGFWFI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409  78 YSPHRWQTWSILGTSLIIFVTWFLVEVSVAINAWYAPFYDLIQKALSAPNRVPIGELYNQLKIFMGIAMIAVTVAVLNNF 157
Cdd:PRK11098  81 YSPHPWQRWSILGSALIIFVTWFLVQVSVAVNAWYAPFYDLIQTALSSPGKVTIGQFYSEVGVFLGIALIAVVISVLNNF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 158 FVSHYVFRWRTAMNEFYMTHWERLRHIEGAAQRVQEDTMRFASTLEDMGVSLLNAILKLFAFLPILVALSPHISALPIVG 237
Cdd:PRK11098 161 FVSHYVFRWRTAMNEYYMAHWQKLRHIEGAAQRVQEDTMRFASTLENLGVSFINAIMTLIAFLPVLVTLSAHVPELPIVG 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 238 HLPYGLLIPALIWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDPTRAAPPTIKELFRNVRFNYFRLYFHYM 317
Cdd:PRK11098 241 HIPYGLVIAAIVWSLFGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDADRATPPTVRELFSNVRKNYFRLYFHYM 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 318 YFNIARIFYLQVDTVFGLFLLFPSIVAGTITLGLLTQITNVFDQVRNSFQYLINSWTTLVELMSIYKRLRSFEHELDDRD 397
Cdd:PRK11098 321 YFNIARILYLQVDNVFGLFLLFPSIVAGTITLGLMTQITNVFGQVRGSFQYLINSWTTIVELLSIYKRLRSFEAALDGEP 400

                 ....*....
gi 654544409 398 LQEVTNTFS 406
Cdd:PRK11098 401 LQEVDHTLL 409
SbmA COG1133
Peptide antibiotic transporter SbmA/BacA, ABC-type permease family [Defense mechanisms];
1-401 0e+00

Peptide antibiotic transporter SbmA/BacA, ABC-type permease family [Defense mechanisms];


Pssm-ID: 440748  Cd Length: 408  Bit Score: 725.95  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409   1 MFKSFFPKPGPFFLSAFIWALIAVVFWLAGGGAWLTRIV----GATGEVPISAARFWSFSYLLFYAYYALCVGLFALFWF 76
Cdd:COG1133    1 MFKSFFPRPKLFFLSAAIWSLLAVLFWYAGGEGLGASLGlppaAAGAPPPIGAARFWTPDFLWFYAYYALCVGLFAGFWF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409  77 NYSPHRWQTWSILGTSLIIFVTWFLVEVSVAINAWYAPFYDLIQKALSAPNRVPIGELYNQLKIFMGIAMIAVTVAVLNN 156
Cdd:COG1133   81 FYSPHRWQRWSILGSALIIFVTYFSVQVSVAINAWYGPFYDLIQKALSKPGSVTIADFYGQMLTFLGIALIAVTVGVLNA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 157 FFVSHYVFRWRTAMNEFYMTHWERLRHIEGAAQRVQEDTMRFASTLEDMGVSLLNAILKLFAFLPILVALSPHISALPIV 236
Cdd:COG1133  161 FFVSHYVFRWRTAMNDYYMAHWPRLRHIEGASQRVQEDTMRFASIVEGLGVSFIDAVMTLIAFLPVLWALSQHVTELPII 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 237 GHLPYGLLIPALIWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDPTRAAPPTIKELFRNVRFNYFRLYFHY 316
Cdd:COG1133  241 GEVPYSLVWAAIFWSLFGTVLLALVGIKLPGLEFRNQRVEAAYRKELVYGEDDAERAQPPTVRELFSNVRRNYFRLYFHY 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 317 MYFNIARIFYLQVDTVFGLFLLFPSIVAGTITLGLLTQITNVFDQVRNSFQYLINSWTTLVELMSIYKRLRSFEHELDDR 396
Cdd:COG1133  321 LYFNVARYLYLQADNIFPLFILVPSIVAGKITLGLMQQISNAFGQVRSSFQYLVNSWTTIVELLSIYKRLRAFEAAIDDE 400

                 ....*
gi 654544409 397 DLQEV 401
Cdd:COG1133  401 PLPEI 405
SbmA_BacA pfam05992
SbmA/BacA-like family; The Rhizobium meliloti bacA gene encodes a function that is essential ...
80-393 0e+00

SbmA/BacA-like family; The Rhizobium meliloti bacA gene encodes a function that is essential for bacterial differentiation into bacteroids within plant cells in the symbiosis between R. meliloti and alfalfa. An Escherichia coli homolog of BacA, SbmA, is implicated in the uptake of microcins and bleomycin. This family is likely to be a subfamily of the ABC transporter family.


Pssm-ID: 461797 [Multi-domain]  Cd Length: 314  Bit Score: 532.38  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409   80 PHRWQTWSILGTSLIIFVTWFLVEVSVAINAWYAPFYDLIQKALSAPNRVPIGELYNQLKIFMGIAMIAVTVAVLNNFFV 159
Cdd:pfam05992   1 PHKWQLWSILGTALILFVTWFQVQVDVAINAWYGPFYDLIQKALASPNAVTIGEFYASLLVFLGIAFIYVTIAVLNLFFV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409  160 SHYVFRWRTAMNEFYMTHWERLRHIEGAAQRVQEDTMRFASTLEDMGVSLLNAILKLFAFLPILVALSPHISALPIVGHL 239
Cdd:pfam05992  81 SHYVFRWRTAMNDYYTSHWQQLRHIEGASQRVQEDTMRFASIVEDLGVSLVRAIMTLIAFLPVLFGLSKHVPVLPIIGDI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409  240 PYGLLIPALIWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDPTRAAPPTIKELFRNVRFNYFRLYFHYMYF 319
Cdd:pfam05992 161 PHSLVWAAVVWSLGGTVFLAVVGIKLPGLEFNNQKVEAAYRKELVYGEDDATRATPKTLKELFSDVRKNYFRLYFHYMYF 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 654544409  320 NIARIFYLQVDTVFGLFLLFPSIVAGTITLGLLTQITNVFDQVRNSFQYLINSWTTLVELMSIYKRLRSFEHEL 393
Cdd:pfam05992 241 NIARIFYLQLDNLFGYIFLAPSIVAGKITLGVMQQITNVFGKVRGSFQYLINSWTTIVELMSIYKRLRAFESVI 314
PRK12369 PRK12369
putative transporter; Reviewed
82-394 4.31e-133

putative transporter; Reviewed


Pssm-ID: 171443 [Multi-domain]  Cd Length: 326  Bit Score: 384.81  E-value: 4.31e-133
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409  82 RWQTWSILGTSLIIFVTWFLVEVSVAINAWYAPFYDLIQKALSAPNRVPIGELYNQLKIFMGIAMIAVTVAVLNNFFVSH 161
Cdd:PRK12369  10 KWALWAYGGLFFILLSLWYQVSLNVAINEWYGDFYDLLQKAKIEPNNHTAGDFWASILSFLAIAMPYVLIATVVDYFASH 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 162 YVFRWRTAMNEFYMTHWERLRH-IEGAAQRVQEDTMRFASTLEDMGVSLLNAILKLFAFLPILVALSPHISaLPIVGHLP 240
Cdd:PRK12369  90 YAFRWREAMTFSYLKFWRNKRDnIEGSSQRIQEDTYRFAKIMESLGLSFLRAIMTLIAFIPILWGLSDGVS-LPFLKDIP 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 241 YGLLIPALIWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDPTR-AAPPTIKELFRNVRFNYFRLYFHYMYF 319
Cdd:PRK12369 169 GSLVWIALLISLGGLVISWFVGIKLPGLEYNNQKVEAAFRKELVYAEDDKKNyAKPETLIELFTGLRFNYFRLFLHYGYF 248
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 654544409 320 NIARIFYLQVDTVFGLFLLFPSIVAGTITLGLLTQITNVFDQVRNSFQYLINSWTTLVELMSIYKRLRSFEHELD 394
Cdd:PRK12369 249 NIWLISFSQMMVIVPYLIMAPGLFAGVITLGVLMQISNAFSQVRSSFSVFIRNWTTITELRSIYKRLKEFEKNIE 323
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
69-402 2.12e-50

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 178.46  E-value: 2.12e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409  69 GLFALFWfnYSPHRWQTWSILGtsLIIFVTWFLVEVSVAINAWYAPFYDliqkALSAPNrvpIGELYNQLKIFMGIAMIA 148
Cdd:COG4178    9 RLARPYW--RSEEKWKAWGLLA--LLLLLTLASVGLNVLLNFWNRDFYD----ALQARD---AAAFWQQLGVFALLAAIS 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 149 VTVAVLNNFFVSHYVFRWRTAMNEFYMTHW------ERLRHIEGAA----QRVQEDTMRFASTLEDMGVSLLNAILKLFA 218
Cdd:COG4178   78 ILLAVYQTYLRQRLQIRWREWLTERLLDRWlsnrayYRLQLSGGEIdnpdQRIAEDIRLFTETTLSLSLGLLSSVVTLIS 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 219 FLPILVALSPHISaLPIVGH---LPYGLLIPALIWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVY---------- 285
Cdd:COG4178  158 FIGILWSLSGSLT-FTLGGYsitIPGYMVWAALIYAIIGTLLTHLIGRPLIRLNFEQQRREADFRFALVRvrenaesial 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409 286 --GEDDPTRaappTIKELFRNVRFNYFRLYFHYMYFNIARIFYLQVDTVFGLFLLFPSIVAGTITLGLLTQITNVFDQVR 363
Cdd:COG4178  237 yrGEAAERR----RLRRRFDAVIANWRRLIRRQRNLTFFTTGYGQLAVIFPILVAAPRYFAGEITLGGLMQAASAFGQVQ 312
                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 654544409 364 NSFQYLINSWTTLVELMSIYKRLRSFEHELDDRDLQEVT 402
Cdd:COG4178  313 GALSWFVDNYQSLAEWRATVDRLAGFEEALEAADALPEA 351
ABC_membrane_2 pfam06472
ABC transporter transmembrane region 2; This domain covers the transmembrane of a small family ...
137-280 5.86e-05

ABC transporter transmembrane region 2; This domain covers the transmembrane of a small family of ABC transporters and shares sequence similarity with pfam00664. Mutations in this domain in Swiss:P28288 are believed responsible for Zellweger Syndrome-2; mutations in Swiss:P33897 are responsible for recessive X-linked adrenoleukodystrophy. A Saccharomyces cerevisiae homolog is involved in the import of long-chain fatty acids.


Pssm-ID: 399466  Cd Length: 269  Bit Score: 44.52  E-value: 5.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654544409  137 QLKIFMGIAMIAVTVAVLNNFFVSHYVFRWRTAMNEFYMTHW------ERLRHIEG----AAQRVQEDTMRFASTLEDMG 206
Cdd:pfam06472  56 LLLKWALLAVPASFVNSALKYLTQRLALRFRTRLTRHLHDEYlkgrtyYKMSNLDGridnPDQRITQDVEKFCSSLSDLY 135
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 654544409  207 VSLLNAILKLFAFLPILVALSphisalpivghlpyGLLIPALIWS--LMGTGLLAVVGIKLPGLEFKNQRVEAAYR 280
Cdd:pfam06472 136 SNLLKPILDIILFTFRLWRLS--------------GWRGPAILFLyvLLSAVILRRLSPPFGKLVAEEQKLEGEFR 197
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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