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Conserved domains on  [gi|654546248|ref|WP_028013954|]
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MULTISPECIES: histidine ABC transporter permease HisQ [Enterobacter]

Protein Classification

histidine ABC transporter permease HisQ( domain architecture ID 10794139)

histidine ABC transporter permease HisQ is required to relay the ATPase-inducing signal from the solute-binding protein to HisP

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK15135 PRK15135
histidine ABC transporter permease HisQ;
1-228 2.62e-143

histidine ABC transporter permease HisQ;


:

Pssm-ID: 185089 [Multi-domain]  Cd Length: 228  Bit Score: 399.55  E-value: 2.62e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   1 MLYGFSGVILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIALNSVT 80
Cdd:PRK15135   1 MLYGFSGVILQGALVTLELALSSVVLAVIIGLIGAGGKLSQNRLLGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNSVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  81 DAMGMGQIDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQV 160
Cdd:PRK15135  81 EALGVGQIDIDPMVAGIITLGFIYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 654546248 161 ILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTVSNGVLLLLERRYSVGVKRADL 228
Cdd:PRK15135 161 ILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLWLERRYSVGVKRADL 228
 
Name Accession Description Interval E-value
PRK15135 PRK15135
histidine ABC transporter permease HisQ;
1-228 2.62e-143

histidine ABC transporter permease HisQ;


Pssm-ID: 185089 [Multi-domain]  Cd Length: 228  Bit Score: 399.55  E-value: 2.62e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   1 MLYGFSGVILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIALNSVT 80
Cdd:PRK15135   1 MLYGFSGVILQGALVTLELALSSVVLAVIIGLIGAGGKLSQNRLLGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNSVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  81 DAMGMGQIDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQV 160
Cdd:PRK15135  81 EALGVGQIDIDPMVAGIITLGFIYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 654546248 161 ILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTVSNGVLLLLERRYSVGVKRADL 228
Cdd:PRK15135 161 ILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLWLERRYSVGVKRADL 228
ArtQ COG4215
ABC-type arginine transport system, permease component [Amino acid transport and metabolism];
1-228 8.64e-115

ABC-type arginine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443361 [Multi-domain]  Cd Length: 238  Bit Score: 327.47  E-value: 8.64e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   1 MLYGFSGVILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIALNSVT 80
Cdd:COG4215   10 GLQGWGPALLAGALVTLELALLSLLLGLVLGLLGALAKLSGNRPLRWLATGYTTVVRGVPDLLLILLLYFGGQILLNALA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  81 DAMGMGQ-IDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQ 159
Cdd:COG4215   90 DLFGYDGfIEINPFVAGVLALGFVFGAYATEVFRGAFLAVPKGQIEAARAYGMSRWQVFRRILLPQMWRYALPGLGNNWL 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 654546248 160 VILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTVSNGVLLLLERRYSVGVKRADL 228
Cdd:COG4215  170 VLLKDTALVSVIGLVDLVRQAQEAAGSTREPFTFYLAAALIYLALTTVSELVLARLERRASRGVRRAAG 238
ectoine_ehuC TIGR03004
ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are ...
 4-222 2.62e-23

ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons. Permease subunits EhuC and EhuD are homologous.


Pssm-ID: 132049 [Multi-domain]  Cd Length: 214  Bit Score: 93.37  E-value: 2.62e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248    4 GFSGVILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIAlnsvtdam 83
Cdd:TIGR03004   2 AYLPLLLQGAWVTMQITLAGSVLATVLAFFAGLGRVSGGPILRTVALCYIEVFRGTSLLVQLFWFYFVLPLI-------- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   84 gmgQIDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQVILK 163
Cdd:TIGR03004  74 ---GLSLDPVTTGVMVLGLHAGAYGAEIVRGALSSVSVQQLEACRALNFTRFQTLRRISLPQALVEMMPAFGNLAIELLK 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 654546248  164 ATALVSLLGLEDVVKATQLAGKSTWE---PFYFAVVCgaiYLVFTTVSNGVLLLLERRYSVG 222
Cdd:TIGR03004 151 LTSLVSLISLADLTFAAQSIRNLTLDtlsIFAITLLC---YFVMALIIMLIMRVLERVVRRG 209
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 13-207 3.82e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 76.16  E-value: 3.82e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  13 ALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIALNsvtdamgmGQIDIDP 92
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG--------WGILPGL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  93 MVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQVILKATALVSLLG 172
Cdd:cd06261   73 GLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLG 152

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 654546248 173 LEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTV 207
Cdd:cd06261  153 GGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLL 187
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 32-221 1.98e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 63.47  E-value: 1.98e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   32 LAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIalnsvtdamgmgQIDIDPMVAGIITLGFIYGAYFTET 111
Cdd:pfam00528   3 PLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAIL------------SILGHGILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  112 FRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQVILKATALVSLL----GLEDVVKATQLAGKST 187
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|....
gi 654546248  188 WEPFYFaVVCGAIYLVFTTVSNGVLLLLERRYSV 221
Cdd:pfam00528 151 EIQGPV-LAAALILLLLNLLVDILQRLLDPRVRK 183
 
Name Accession Description Interval E-value
PRK15135 PRK15135
histidine ABC transporter permease HisQ;
1-228 2.62e-143

histidine ABC transporter permease HisQ;


Pssm-ID: 185089 [Multi-domain]  Cd Length: 228  Bit Score: 399.55  E-value: 2.62e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   1 MLYGFSGVILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIALNSVT 80
Cdd:PRK15135   1 MLYGFSGVILQGALVTLELALSSVVLAVIIGLIGAGGKLSQNRLLGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNSVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  81 DAMGMGQIDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQV 160
Cdd:PRK15135  81 EALGVGQIDIDPMVAGIITLGFIYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 654546248 161 ILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTVSNGVLLLLERRYSVGVKRADL 228
Cdd:PRK15135 161 ILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLWLERRYSVGVKRADL 228
ArtQ COG4215
ABC-type arginine transport system, permease component [Amino acid transport and metabolism];
1-228 8.64e-115

ABC-type arginine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443361 [Multi-domain]  Cd Length: 238  Bit Score: 327.47  E-value: 8.64e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   1 MLYGFSGVILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIALNSVT 80
Cdd:COG4215   10 GLQGWGPALLAGALVTLELALLSLLLGLVLGLLGALAKLSGNRPLRWLATGYTTVVRGVPDLLLILLLYFGGQILLNALA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  81 DAMGMGQ-IDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQ 159
Cdd:COG4215   90 DLFGYDGfIEINPFVAGVLALGFVFGAYATEVFRGAFLAVPKGQIEAARAYGMSRWQVFRRILLPQMWRYALPGLGNNWL 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 654546248 160 VILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTVSNGVLLLLERRYSVGVKRADL 228
Cdd:COG4215  170 VLLKDTALVSVIGLVDLVRQAQEAAGSTREPFTFYLAAALIYLALTTVSELVLARLERRASRGVRRAAG 238
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 9-222 3.63e-53

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 170.26  E-value: 3.63e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   9 ILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIAlnsvtdamgmgQI 88
Cdd:COG0765   15 LLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPLL-----------GI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  89 DIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQVILKATALV 168
Cdd:COG0765   84 DLSPFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFISLLKDTSLV 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 654546248 169 SLLGLEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTVSNGVLLLLERRYSVG 222
Cdd:COG0765  164 SVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRLARG 217
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
9-220 6.05e-48

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 157.53  E-value: 6.05e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   9 ILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYG-------------LQIA 75
Cdd:PRK11123   7 LASAAGMTVGLAVCALIVGLALAMLFAVWESAKWRPVAWPGTALVTLLRGLPEILVVLFIYFGssqllltlsdgftLNLG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  76 LNSVTDAMGMGQIDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIG 155
Cdd:PRK11123  87 FVQIPVQMDIENFEVSPFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLG 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 654546248 156 NNWQVILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTVSNGVLLLLERRYS 220
Cdd:PRK11123 167 NQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIIAAAIYLVITLISQYILKRIELRAT 231
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 9-226 1.80e-42

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 143.31  E-value: 1.80e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   9 ILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLqialnsvtdamgmGQI 88
Cdd:COG4160   13 LLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYGL-------------GQF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  89 DI-----------DPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNn 157
Cdd:COG4160   80 EWvreswlwpllrDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRALPAYSN- 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 654546248 158 wQVIL--KATALVSLLGLEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTVSNGVLLLLERRYSVGVKRA 226
Cdd:COG4160  159 -EVILmlKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLLRHLRPR 228
PRK15100 PRK15100
cystine ABC transporter permease;
9-218 2.40e-27

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 104.06  E-value: 2.40e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   9 ILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGL-QIAlnsvtdamgmgq 87
Cdd:PRK15100  15 LLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYVSIFRGTPLIAQLFMIYYGLpQFG------------ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  88 IDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQVILKATAL 167
Cdd:PRK15100  83 IELDPIPAAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDTSL 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 654546248 168 VSLLGLEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTVSNGVLLLLERR 218
Cdd:PRK15100 163 AATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSALQNRFENQ 213
PRK15069 PRK15069
histidine ABC transporter permease HisM;
3-219 7.10e-24

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 95.12  E-value: 7.10e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   3 YGFSGVIlqgalVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPdLVLMLLIFYGLQIALNSVTDA 82
Cdd:PRK15069  18 YRFTGLA-----ITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTP-LYVQLLVFYTGMYSLEIVRGT 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  83 MGMGQIDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQVIL 162
Cdd:PRK15069  92 DLLDAFFRSGLNCTILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEVILML 171

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 654546248 163 KATALVSLLGLEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTVSNGVLLLLERRY 219
Cdd:PRK15069 172 HATTLAFTATVPDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERRW 228
ectoine_ehuC TIGR03004
ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are ...
 4-222 2.62e-23

ectoine/hydroxyectoine ABC transporter, permease protein EhuC; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons. Permease subunits EhuC and EhuD are homologous.


Pssm-ID: 132049 [Multi-domain]  Cd Length: 214  Bit Score: 93.37  E-value: 2.62e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248    4 GFSGVILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIAlnsvtdam 83
Cdd:TIGR03004   2 AYLPLLLQGAWVTMQITLAGSVLATVLAFFAGLGRVSGGPILRTVALCYIEVFRGTSLLVQLFWFYFVLPLI-------- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   84 gmgQIDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQVILK 163
Cdd:TIGR03004  74 ---GLSLDPVTTGVMVLGLHAGAYGAEIVRGALSSVSVQQLEACRALNFTRFQTLRRISLPQALVEMMPAFGNLAIELLK 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 654546248  164 ATALVSLLGLEDVVKATQLAGKSTWE---PFYFAVVCgaiYLVFTTVSNGVLLLLERRYSVG 222
Cdd:TIGR03004 151 LTSLVSLISLADLTFAAQSIRNLTLDtlsIFAITLLC---YFVMALIIMLIMRVLERVVRRG 209
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 9-218 7.66e-23

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 92.04  E-value: 7.66e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   9 ILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIALNSVTdamgmgqi 88
Cdd:PRK09494  15 LLEGAKMTLWISVLGLAGGLVIGLLAGFARAYGGWIANHIALVFIELIRGTPIVVQVMFIYFALPMAFNDLR-------- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  89 dIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQVILKATALV 168
Cdd:PRK09494  87 -IDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRYVIGPLALRRMLPPLGNQWIISIKDTSLF 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 654546248 169 SLLGLEDVVKATQ--LAGKSTWEPFYFAVvcGAIYLVFTTVSNGVLLLLERR 218
Cdd:PRK09494 166 IVIGVAELTRQGQeiIAGNFRALEIWSAV--AVIYLIITLVLSFILRRLERR 215
artM PRK11122
arginine ABC transporter permease ArtM;
8-218 6.05e-18

arginine ABC transporter permease ArtM;


Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 79.23  E-value: 6.05e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   8 VILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQiALNSVTDAMGMGQ 87
Cdd:PRK11122   7 ELLKGLHTSLTLTVASLLVALVLALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPG-QFPWLQEYPWLWH 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  88 IDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFrRIMFPAMMRYALPGIGNNWQVILKATAL 167
Cdd:PRK11122  86 LLSQPWLCAMLALALNSAAYSTQLFYGAVRAIPEGQWQSCAALGMSKKQTL-RILLPYAFKRALSSYSNEVVLVFKSTSL 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 654546248 168 VSLLGLEDVVKATQLAGKSTWEPFYFAVVcGAIYLVFTTVSNGVLLLLERR 218
Cdd:PRK11122 165 AYTITLMDVMGYSQLLYGRTYDVMVFGAA-GIIYLVVNGLLTLLMRLIERK 214
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 13-207 3.82e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 76.16  E-value: 3.82e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  13 ALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIALNsvtdamgmGQIDIDP 92
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG--------WGILPGL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  93 MVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQVILKATALVSLLG 172
Cdd:cd06261   73 GLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLG 152

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 654546248 173 LEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTV 207
Cdd:cd06261  153 GGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLL 187
HEQRo_perm_3TM TIGR01726
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ...
 5-114 9.07e-17

amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130787 [Multi-domain]  Cd Length: 99  Bit Score: 72.95  E-value: 9.07e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248    5 FSGVILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIAlnsvtdamg 84
Cdd:TIGR01726   1 NLPFLLKGLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIYFGLPLI--------- 71

                          90       100       110
                  ....*....|....*....|....*....|
gi 654546248   85 mgQIDIDPMVAGIITLGFIYGAYFTETFRG 114
Cdd:TIGR01726  72 --GIRLSPLTAAVIALTLFYGAYLAEIFRG 99
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
9-218 2.19e-15

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 72.17  E-value: 2.19e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   9 ILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPdLVLMLLIFYglQIALNSVTDAMGMGQI 88
Cdd:PRK15107  16 LLDGLVITLKITVTAVVIGILWGTILAVMRLSSFKPVAWFAKAYVNVFRSIP-LVMVLLWFY--LIVPGFLQNVLGLSPK 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  89 DIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQVILKATALV 168
Cdd:PRK15107  93 TDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQGIVLFQDTSLV 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 654546248 169 SLLGLEDVVKATQLAGKSTWEPFYFAVVCGAIYLVFTTVSNGVLLLLERR 218
Cdd:PRK15107 173 YVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSYLKKR 222
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 32-221 1.98e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 63.47  E-value: 1.98e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   32 LAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIalnsvtdamgmgQIDIDPMVAGIITLGFIYGAYFTET 111
Cdd:pfam00528   3 PLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAIL------------SILGHGILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  112 FRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQVILKATALVSLL----GLEDVVKATQLAGKST 187
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|....
gi 654546248  188 WEPFYFaVVCGAIYLVFTTVSNGVLLLLERRYSV 221
Cdd:pfam00528 151 EIQGPV-LAAALILLLLNLLVDILQRLLDPRVRK 183
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 3-147 5.98e-07

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 48.54  E-value: 5.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   3 YGFSGVILQGALVTLELAISSVVLAVLIG--LAGAGAK-LSANKPLALIFEGYTTLIRGVPDLVL-MLLIFyglqialns 78
Cdd:COG3639   43 WSYLPDLLSALLETLAIALLGTLLGAVLAlpLAFLAARnLAPNPWVRLLARRLLNVLRAIPELVWaLIFVA--------- 113

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 654546248  79 vtdAMGMGqididpMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMM 147
Cdd:COG3639  114 ---AVGLG------PFAGVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQVIRYGVLPQVL 173
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 6-154 1.10e-05

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 45.14  E-value: 1.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   6 SGVILQGALVTLELAISSVVLAVLIGLAgAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYglqialnsvtdAMGM 85
Cdd:COG0600   56 SGELWEHLLASLLRVLLGFALAALLGVP-LGLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLIL-----------WFGI 123

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 654546248  86 GqidiDPMVAGIITLGFIYGAYFTeTFRGAyMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGI 154
Cdd:COG0600  124 G----EASKIFVIFLGAFFPILLN-TAAGV-RSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGL 186
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 9-184 4.62e-04

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 40.09  E-value: 4.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   9 ILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVL---MLLIFYGLQIALNSVTdamgm 85
Cdd:COG1177   59 LLDALLNSLLIALLSTLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLgvaLLLLFSALGLSGGLWG----- 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  86 gqididpMVAGIITLGFiygAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMryalPGignnwqvILKAT 165
Cdd:COG1177  134 -------LILAHVVFTL---PFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIA----PG-------ILAGA 192

                        170
                 ....*....|....*....
gi 654546248 166 ALVSLLGLEDVVKATQLAG 184
Cdd:COG1177  193 LLAFTLSFDEFVITLFLAG 211
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 8-152 6.44e-04

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 40.05  E-value: 6.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   8 VILQGALVTLELAISSVVLAVLIGL-AGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLLIFYGLQIALNsVTDAMGMG 86
Cdd:COG0601   90 LIAERLPVTLELALLALLLALLIGIpLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG-WLPVSGRV 168

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 654546248  87 QIDIDP------MVAGIITLGFIYGAYFTETFRGAYMAVPR-GHIEAATAFGFTSsqtfRRIMFpammRYALP 152
Cdd:COG0601  169 SPWEDFldalrhLILPALTLALGSLAGIARLTRSSMLEVLGqDYVRTARAKGLSE----RRVLL----RHALR 233
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
5-175 1.18e-03

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 39.37  E-value: 1.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   5 FSGVILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLV--LMLLIFYGLQIALNSV-TD 81
Cdd:COG1178   48 SDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVvaLAWIALFGPNGLLNTLlRA 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  82 AMGMGQIDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPaMMRYALPGignnwqvi 161
Cdd:COG1178  128 LFGLEPPDIYGLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLP-LLRPAIAA-------- 198

                        170
                 ....*....|....
gi 654546248 162 lkATALVSLLGLED 175
Cdd:COG1178  199 --GALLVFLLCLAD 210
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
5-218 2.17e-03

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 38.60  E-value: 2.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248   5 FSGVILQGALVTLELAISSVVLAVLIGLAGAGAKLSANKPLALIFEGYTTLIRGVPDLVLMLlifyGLQIALNSVtdamg 84
Cdd:COG1178  332 LDPSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVLGL----GLLLLFNRP----- 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654546248  85 MGQIDIDPMVAGIITLGFIYGAYFTETFRGAYMAVPRGHIEAATAFGFTSSQTFRRIMFPAMMRYALPGIGNNWQVILKA 164
Cdd:COG1178  403 LPLLLYGTLAILVLAYVVRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKE 482

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 654546248 165 TALVSLLGLEDV----VKATQLAGKSTWEPfyfAVVCGAIYLVFTTVSNGVLLLLERR 218
Cdd:COG1178  483 LSATLLLRPPGFetlaVLIYQLASSGRYGE---AAALALLLVLVSLLPVLLLERLLGR 537
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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